WO2005016275A3 - Formulations containing an immune response modifier - Google Patents

Formulations containing an immune response modifier Download PDF

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Publication number
WO2005016275A3
WO2005016275A3 PCT/US2004/025277 US2004025277W WO2005016275A3 WO 2005016275 A3 WO2005016275 A3 WO 2005016275A3 US 2004025277 W US2004025277 W US 2004025277W WO 2005016275 A3 WO2005016275 A3 WO 2005016275A3
Authority
WO
WIPO (PCT)
Prior art keywords
amines
immune response
response modifier
aqueous
formulations containing
Prior art date
Application number
PCT/US2004/025277
Other languages
French (fr)
Other versions
WO2005016275A2 (en
Inventor
David M Hammerbeck
Cynthia A Guy
Suzanne S Leung
Original Assignee
3M Innovative Properties Co
David M Hammerbeck
Cynthia A Guy
Suzanne S Leung
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 3M Innovative Properties Co, David M Hammerbeck, Cynthia A Guy, Suzanne S Leung filed Critical 3M Innovative Properties Co
Priority to AU2004264336A priority Critical patent/AU2004264336B2/en
Priority to US10/595,049 priority patent/US8221771B2/en
Priority to EP04780166A priority patent/EP1651190B1/en
Priority to JP2006522714A priority patent/JP2007501252A/en
Priority to CA2534313A priority patent/CA2534313C/en
Publication of WO2005016275A2 publication Critical patent/WO2005016275A2/en
Publication of WO2005016275A3 publication Critical patent/WO2005016275A3/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents

Abstract

Pharmaceutical formulations in an aqueous (preferably, sprayable) formulaiton including an immune response modifier (IRM), such as those chosen from imidazoquinoline amines, tetrahydroimidazoquinoline amines, imidazopyridine amines, 6,7-fused cycloalkylimidazopyridine amines, 1,2-bridged imidazoquinoline amines, imidazonaphthyridine amines, imidazotetrahydronaphthyridine amines, oxazoloquinoline amines, thiazoloquinoline amines, oxazolopyridine amines, thiazolopyridine amines, oxazolonaphthyridine amines, thiazolonaphthyridine amines, and 1H-imidazo dimers fused to pyridine amines, quinoline amines, tetrahydroquinoline amines, naphthyridine amines, or tetrahydronaphthyridine amines, are provided. In one embodiment, the aqueous formulations are advantageous for treatment and/or prevention of allergic rhinitis, viral infections, sinusitis, and asthma.
PCT/US2004/025277 2003-08-05 2004-08-05 Formulations containing an immune response modifier WO2005016275A2 (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
AU2004264336A AU2004264336B2 (en) 2003-08-05 2004-08-05 Formulations containing an immune response modifier
US10/595,049 US8221771B2 (en) 2003-08-05 2004-08-05 Formulations containing an immune response modifier
EP04780166A EP1651190B1 (en) 2003-08-05 2004-08-05 Formulations containing an immune response modifier
JP2006522714A JP2007501252A (en) 2003-08-05 2004-08-05 Formulation containing immune response modifier
CA2534313A CA2534313C (en) 2003-08-05 2004-08-05 Formulations containing an immune response modifier

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US49310903P 2003-08-05 2003-08-05
US60/493,109 2003-08-05

Publications (2)

Publication Number Publication Date
WO2005016275A2 WO2005016275A2 (en) 2005-02-24
WO2005016275A3 true WO2005016275A3 (en) 2005-04-14

Family

ID=34193164

Family Applications (2)

Application Number Title Priority Date Filing Date
PCT/US2004/025241 WO2005016273A2 (en) 2003-08-05 2004-08-05 Infection prophylaxis using immune response modifier compounds
PCT/US2004/025277 WO2005016275A2 (en) 2003-08-05 2004-08-05 Formulations containing an immune response modifier

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PCT/US2004/025241 WO2005016273A2 (en) 2003-08-05 2004-08-05 Infection prophylaxis using immune response modifier compounds

Country Status (7)

Country Link
US (2) US8221771B2 (en)
EP (2) EP1651216A2 (en)
JP (2) JP2007501251A (en)
CN (1) CN1852711A (en)
AU (2) AU2004264336B2 (en)
CA (2) CA2534313C (en)
WO (2) WO2005016273A2 (en)

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