WO2005025448A2 - Wound healing apparatus with bioabsorbable material and suction tubes - Google Patents

Wound healing apparatus with bioabsorbable material and suction tubes Download PDF

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Publication number
WO2005025448A2
WO2005025448A2 PCT/US2004/029309 US2004029309W WO2005025448A2 WO 2005025448 A2 WO2005025448 A2 WO 2005025448A2 US 2004029309 W US2004029309 W US 2004029309W WO 2005025448 A2 WO2005025448 A2 WO 2005025448A2
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WO
WIPO (PCT)
Prior art keywords
wound
wound healing
sensor
healing apparatus
flexible tubes
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Application number
PCT/US2004/029309
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French (fr)
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WO2005025448A3 (en
Inventor
Richard L. Watson, Jr.
Original Assignee
Spheric Partners, Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Spheric Partners, Ltd. filed Critical Spheric Partners, Ltd.
Priority to AT04783527T priority Critical patent/ATE474535T1/en
Priority to DE602004028255T priority patent/DE602004028255D1/en
Priority to EP04783527A priority patent/EP1663063B1/en
Publication of WO2005025448A2 publication Critical patent/WO2005025448A2/en
Publication of WO2005025448A3 publication Critical patent/WO2005025448A3/en

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M27/00Drainage appliance for wounds or the like, i.e. wound drains, implanted drains

Abstract

An apparatus for placement in a wound to promote healing, and a method of treating wounds using such apparatus. The apparatus comprises a bioabsorbable fabric supported by a skeleton of impervious flexible members, such as TeflonTM tubes. When placed inside the wound, the bioabsorbable fabric absorbs into the body within about 5 to 10 days. As the fabric is being absorbed, it serves as a framework for fibroblasts to bridge the gap in the wounded tissue and thereby promote healing. The tubes serve as conduits to remove excess fluids from the wound, preferably under the power of a suction device to which the tubes are connected outside the body. After the fabric is absorbed by the body, the flexible tubes are removed. An expandable embodiment may be deployed into a wound cavity via an introducer tube and plunger. The apparatus may incorporate various sensors.

Description

I
WOUND HEALING APPARATUS WITH BIOABSORBABLE MATERIAL AND SUCTION TUBES INVENTOR: RICHARD L. WATSON, JR. CROSS-REFERENCE TO RELATED APPLICATION This application claims the benefit of U.S. Provisional Patent Application No. 60/501,799 filed on September 10, 2003, and U.S. Utility Patent Application No. 10/818,454, filed on April 5, 2004, which are incorporated herein by reference. BACKGROUND OF THE INVENTION This invention relates generally to the wound healing arts, and more particularly to a novel wound healing apparatus containing bioabsorbable material for promoting new tissue growth and suction tubes for removing excess fluid from the wound. SUMMARY OF THE INVENTION The present invention is directed to an apparatus for placement in a wound to promote healing of the wound, and a method of treating a wound using such an apparatus.
The apparatus preferably comprises a bioabsorbable mesh fabric made of threads that are absorbable into the human body. Examples of suitable threads for foπriing the mesh fabric include synthetic absorbable sutures, such as coated VICRYL RAPIDE™ (polyglactin
910) sutures available from Ethicon (Somerville, NJ). When placed inside the body, such suture material typically absorbs into the body within about 5 to 10 days. As the mesh fabric is being absorbed, it serves as a framework for fϊbroblasts to bridge the gap in the wounded tissue and thereby promote healing. The mesh fabric is preferably supported by a skeleton of impervious flexible tubes (such as Teflon™ tubes), which are removed from the body after the mesh fabric is absorbed. The flexible tubes also serve as conduits to remove excess fluids from the wound, preferably under the power of a suction device to which the tubes are connected outside the body. The tubes may have fenestrations or openings along their lengths to help remove the excess fluid from the wound. Preferably, an oxygen saturation sensor is incorporated into the apparatus for monitoring the oxygen saturation level of blood in the vicinity of the wound. The present apparatus and method may be used with animals as well as humans. BRIEF DESCRIPTION OF THE DRAWINGS Fig. 1 is a side view of an expandable embodiment of a wound healing apparatus in accordance with the present invention in an undeployed condition. Fig. 2 is a side view of the expandable embodiment of Fig. 1 in a deployed condition. Fig. 3 is a side view of the expandable embodiment of Fig. 1 partially deployed into a wound cavity. Fig. 4 is a side view of the expandable embodiment of Fig. 1 fully deployed into a wound cavity. Fig. 5 is a side view of the expandable embodiment of Fig. 1 fully deployed into a wound cavity with the bioabsorbable material having been absorbed. Fig. 6 is a plan view of an alternative embodiment of a wound healing apparatus in accordance with the present invention. Fig. 7 is an end view of the alternative embodiment of Fig. 6 taken in the direction of arrows 7-7. Fig. 8 is an enlarged view of a suction tube in accordance with the present invention. Fig. 9 is another alternative embodiment of the present invention. Fig. 10 is yet another alternative embodiment of the present invention. Fig. 11 is still another alternative embodiment of the present invention. Fig. 12 is a plan view of yet another alternative embodiment of the present invention. Fig. 13 is a plan view of still another alternative embodiment of the present invention. DETAILED DESCRIPTION OF A PREFERRED EMBODIMENT Referring to Figs. 1-5, a wound healing device 10 comprises a bioabsorbable mesh fabric material 22 and flexible tubes 20 arranged to form an expandable bag that is designed to be deployed into a wound cavity 28, such as a seroma., created in human flesh after the removal of a bulk of tissue during surgery or other invasive trauma to the body. Such interior cavities commonly develop after the surgery is completed and the skin 26 is closed. Examples of suitable threads for forming the mesh fabric material 22 include synthetic absorbable sutures, such as coated VICRYL RAPIDE™ (polyglactin 910) sutures available from Ethicon (Somerville, NJ). Tubes 20 are preferably made of a material that is impervious to the body, such as Teflon™ material. The bag is deployable from an introducer tube 12 that preferably has an expandable tip 14 and a plunger 16. The tip 14 of the introducer tube 12 is inserted through the skin 26 and into the cavity 28 as shown in Fig. 3, and then the plunger 16 is used to deploy and expand the mesh bag within the cavity 28 as shown in Fig. 4. Plunger 16 preferably has a stop 18 to limit the travel of plunger 16 into introducer tube 12. In a preferred embodiment, the deployed bag is shaped similar to a kitchen whisk. After deployment, introducer tube 12 and plunger 16 are removed from the cavity 28. As shown in Fig. 5, approximately 5 to 10 days after deployment, the bioabsorbable mesh fabric 22 will be fully absorbed into the body, leaving only the tubes 20 which may then be removed from the cavity 28. During the healing process, tubes 20 serve as conduits to remove excess fluid from the wound through evacuation tube 24. Preferably, evacuation tube 24 is connected to a suction device such as a vacuum pump (not shown) outside the body to facilitate removal of excess fluid from the cavity 28. A preferred suction device for use with wound healing device 10 is a personally portable vacuum desiccator as described in U.S. Patent No. 6,648,862 issued to the present inventor, which is incorporated herein by reference. Tubes 20 may have fenestrations or openings along their lengths as described for tubes 32 below to help in removal of excess fluid. Referring to Figs. 6-8, an alternative wound healing apparatus 30 comprises a bioabsorbable mesh fabric 34 supported by a framework of flexible tubes 32 to form a substantially planar sheet that is designed to be implanted in a surgical wound at the time of surgery. Examples of suitable threads for forming the mesh fabric 34 include synthetic absorbable sutures, such as coated VICRYL RAPIDE™ (polyglactin 910) sutures available from Ethicon (Somerville, NJ). Tubes 32 are connected to an evacuation tube 38. Tubes 32 and 38 are preferably made of a material that is impervious to the body, such as Teflon™ material. Like the deployable bag embodiment 10 described above, the sheet- like embodiment 30 serves to promote healing through growth of fibroblasts in the wound, and the tubes 32 serve to remove excess fluid from the wound, preferably Toy connection of evacuation tube 38 to a suction device (not shown), such as a personally portable vacuum desiccator as described in U.S. Patent No. 6,648,862, which is incorporated herein by reference. Tubes 32 preferably have fenestrations or openings 36 to help evacuate excess fluid from the wound. Wound healing apparatus 30 may be placed in trie wound toward the end of surgery, and the skin may be closed over apparatus 30 with tube 38 extending out of the wound. Tubes 32 and 38 are removed from the wound after the mesh fabric material 34 is absorbed into the body. The sheet-like embodiment may be made in any of a number of suitable shapes, such as rectangular (see Fig. 6), oval (see Fig. 9), diamond (see Fig. 10), triangular (see Fig. 11), or the like. For the sake of simplicity and clarity, no bioabsorbable fabric material is shown in Figs. 9-11. Such substantially planar embodiments are especially useful in "flap and graft" plastic surgery procedures to help minimize or avoid disfigurement as the wound heals following surgery. Of course, persons of ordinary skill in the art will appreciate that wound healing devices in accordance with the present invention may also be curved, if desired, rather than being substantially flat, depending on the particular wound to be treated. As an additional benefit, wound healing apparatus 30 may be provided with an oxygen saturation (Sa02) sensor (not shown) for sensing the oxygen saturation level of the blood in the vicinity of the wound. Referring again to Figs. 6 and 7, an oxygen saturation sensor may be placed in the end of one of the tubes 32, and associated power and signal wires (not shown) may be routed from the sensor through tube 32 and tube 38 to the associated signal analyzer (not shown). Similarly, referring to Figs. 1-5, an oxygen saturation sensor may be included in the end of one of the tubes 20 of wound healing device 10, and the power and signal wires may be routed from the sensor through tubes 20 and 24 to the associated signal analyzer. Suitable oxygen saturation sensors and their operation are well known in the art, one example of which is an OxiMax™ sensor available from NellCor Puritan Bennett, Inc. (St. Louis, Missouri). By incorporating an oxygen saturation sensor into a wound healing apparatus in accordance with the present invention, medical personnel are better able to monitor the oxygen saturation level of the blood in the vicinity of the wound as the wound heals in order to evaluate the progress of the healing process. As persons of ordinary skill in the art will appreciate, other biodegradable materials may be used in lieu of or in addition to the above described bioabsorbable mesh fabric in accordance with the present invention. For example, other suitable biodegradable materials include biodegradable plastics such as beta glucan available from Biopolymer Engineering, Inc. (Eagan, Minnesota), which is an extract from brewer's yeast and also serves as an anti-infectant; polyhydroxyalkanoates (PHAs) available from Degradable Solutions AG (Zurich, Switzerland); and hard gelatins such as those used for ingestible capsules available from Capsugel™, a subsidiary of Pfizer, Inc. (Morris Plains, New
Jersey). Fig. 12 illustrates an alternative wound healing apparatus 70 which is similar to apparatus 30 discussed above except that apparatus 70 also includes an electrocardiogram (ECG) sensor, a carbon dioxide (C02) sensor, and an oxygen saturation (Sa02) sensor, as further described below. Like apparatus 30 described above, apparatus 70 preferably has a bioabsorbable mesh fabric (not shown for the sake of clarity) supported "by a framework of flexible tubes 32, which are connected to an evacuation tube 38. Apparatus 70 is used much like apparatus 30 to help heal wounds, but apparatus 70 also provides the capability to monitor ECG activity, C02 levels, and Sa02 levels of blood in the vicinity of the wound during the healing process. To facilitate those monitoring functions, apparatus 70 preferably includes three ECG electrodes 72, 74, 76, a C02 sensor 78, and an Sa02 sensor comprising a light source 80 and a light detector 82 as is known in the art, each of which is preferably disposed on or in one of the tubes 32. Persons of skill in the art will appreciate that the placement of electrodes 72, 74, 76, C02 sensor 78, light source 80, and light detector 82 may vary. The associated electrical power and signal lines (not shown) for the
ECG sensor, C02 sensor, and Sa02 sensor are preferably routed through tubes 32 and 38 to their respective power sources and signal processors (not shown), the configuration and operation of which are well known in the art. Because apparatus 70 is positionable directly in a wound, the ECG sensor, C02 sensor, and Sa02 sensor of apparatus 70 are capable of providing convenient and accurate information as to the ECG activity, C02 levels, and Sa02 levels of blood in the vicinity of the wound, which greatly assists caregivers in monitoring the progress of the healing process. A C02 sensor 78 as described for apparatus 70 above is particularly useful in monitoring a wound for infection when the bioabsorbable material of apparatus 70 contains a PHA material. As is known in the art, PHA. material degrades into C02 and water, and the rate of degradation is markedly increased by elevated levels of bacteria. Thus, if a wound containing PHA material is infected, the bacteria will break down the PHA material at a faster rate, which will increase the rate of production of C02. Accordingly, C02 sensor 78 serves as a convenient means of monitoring the wound for infection. In cooperation with its signal processor, C02 sensor 78 preferably provides a visual or audible indication if the C02 level in the wound reaches or exceeds a certain predetermined level so that a caregiver may check the wound for infection. Alternatively, if a wound being treated with apparatus 70 is known to be infected, C02 sensor 78 and its signal processor may cooperate to provide a visual or audible indication if the C02 level in the wound drops below a certain predetermined level so that a caregiver may know that the infection has sufficiently decreased. The C02 sensor 78 may be provided either as part of the framework of tubes 32 as shown in Fig. 12, or downstream in the evacuation tube 38, or as part of the vacuum source that is connected to evacuation tube 38. The YSI 8500 C02 sensor available from YSI Incorporated (Yellow Springs, Ohio) is an example of a suitable C02 sensor that is adaptable for use in accordance with the present invention. Fig. 13 illustrates another alternative wound healing apparatus 90 which is similar to apparatus 30 discussed above except that apparatus 90 also includes a pair of electrodes 92 and 94 for electric stimulation of the wound and a pressure transducer 96 for measuring blood pressure in the vicinity of the wound. Pressure transducer 96 is preferably a micro pressure transducer such as a Mikro-Tip™ SPR series pressure transducer available from Millar Instruments, Inc. (Houston, Texas) or an Accutorr Plus™ sensor available from Datascope Corporation (Montvale, New Jersey). Like apparatus 30 described above, apparatus 90 preferably has a bioabsorbable nesh fabric (not shown for the sake of clarity) supported by a framework of flexible tubes 32, which are connected to an evacuation tube 38. Apparatus 90 is used much like apparatus 30 to help heal wounds, but apparatus 90 also provides the capability to stimulate the flesh in the wound with electricity, which further promotes healing as is known in the art, and the capability to monitor the blood pressure in the vicinity of the wound, which serves as an indication of whether the wound is healing properly and the general health condition of the patient. Electrodes 92 and 94 and pressure transducer 96 are preferably disposed on or in one of die tubes 32. Persons of skill in the art will appreciate that the placement of electrodes 92 and 94 and pressure transducer 96 may vary. The associated electrical power lines (not shown) for electrodes 92 and 94 and the associated electrical power lines and signal lines (not shown) for pressure transducer 96 are preferably routed through tubes 32 and 38 to their respective power sources and signal processors (not shown), the configuration and operation of which are well known in the art. Referring again to Figs. 12 and 13, the aforementioned ECG sensor 72, 74, 76, C02 sensor 78, Sa02 sensor 80, 82, pressure transducer 96, and electric stimulation electrodes 92, 94 may all be provided in the same wound healing apparatus. If an ECG sensor and electric stimulation electrodes are provided in the same apparatus, the ECG sensor and the electric stimulation electrodes are preferably not operated at the same time to avoid electrical interference. Additionally, because the blood being monitored by the Sa02 sensor 80, 82 is generally pulsing through blood vessels in the flesh at a certain frequency, the signal received by the detector 82 will be periodic, and the period of that signal is indicative of the patient's heart rate. Thus, the heart rate may be calculated from the Sa02 signal, preferably by a computerized signal processor (not shown). Similarly, the ECG electrodes 72, 74, 76 may be used to measure the difference in bioimpedance of adjacent bodily tissue, such as the chest wall, when the patient is inhaling versus when the patient is exhaling and thereby calculate the patient's respiratory rate. The results of the ECG, C02, Sa02, blood pressure, heart rate, and respiratory rate measurements and calculations may be displayed on a monitor (not shown) according to methods well known in the art. Persons of ordinary skill in the art will appreciate ti at tubes 20 and 24 of device 10 shown in Figs. 2-5 and tubes 32 and 38 of devices 30, 70, and 90 shown in Figs. 6, 12, and 13, respectively, may also be used to inject medicine into the wound. For example, liquid antibiotics, angiogenic factors, keratin-based medicine, or other suitable medicines may be injected into t ie wound to help promote healing. Additionally, medicine may be embedded in the bioabsorbable mesh fabric 22 (see Fig. 2) and 34 (see Fig. 6) or other biodegradable material to help promote healing. For example, a conventional antibiotic such as ciprofloxacin or a lyophilized (freezedried) antibiotic that becomes activated upon contact with moisture may be embedded in the bioabsorbable material to help promote healing. Similarly, a keratin-based substance or an angiogenic substance may be embedded in the bioabsorbable material to help promote healing and stimulate the creation of new blood vessels. Although tubes 20 (see Figs. 2-5) and 32 (see Fig. 6) described above are preferably made of an impervious material such as Teflon™, tubes 20 and 32 may be made of a biodegradable material that gets absorbed into the body over a period of time as the wound heals. In such an embodiment, eventually nothing would remain to be pulled out of the wound, and tube 24 or 38 would simply break away from the wound site after a period of time. Examples of suitable biodegradable materials for tubes 20 and 32 may include biodegradable plastics, such as beta glucans, PHAs, and hard gelatins such as those used for ingestible capsules, as described above. Although the foregoing specific details describe a preferred embodiment of this invention, persons reasonably skilled in the art will recognize that various changes may be made in the details of this invention without departing from the spirit and scope of the invention as defined in the appended claims. For example, although die bioabsorbable fabric is generally described herein as a mesh fabric, which is preferably made in a uniform woven fashion, persons of ordinary skill in the art will appreciate that the bioabsorbable fabric may be made in any suitable form, including a nonwoven form, and the openings between the threads forming the fabric and the arrangement of the threads themselves may be nonuniform rather than uniform. Also, although the framework for supporting the bioabsorbable material is preferably comprised of a plurality of flexible tubes in order to provide the capability to remove excess fluid from the wound and to inject medicine into the wound through the tubes, the framework may be comprised of one or more solid, elongated rods, if desired, and such rods may be used in conjunction with or in lieu of tubes. Accordingly, as used herein, the term "skeletal member" means any flexible member suitable for carrying a bioabsorbable fabric or other biodegradable material in accordance with this invention, which may or may not have a conduit, such as a tube, for removing fluid from the wound. Although the skeletal members support the bioabsorbable fabric or other biodegradable material, the bioabsorbable fabric or other biodegradable material may or may not be attached to the skeletal members, such as by adhesive or heat sealing. For example, the fibers of the bioabsorbable fabric may be looped around the skeletal members. As another example, although the flexible framewor and bioabsorbable material of one preferred embodiment are deployable as an expandable bag, the flexible framework and bioabsorbable material need not necessarily form an expandable bag; some other suitable deployed form may be desirable. Persons of ordinary skill in the art will also appreciate that any of the sensors or electrical stimulation electrodes described herein may be used with any wound healing apparatus described herein. Additionally, many other variations of the present invention are possible. Therefore, it should be understood that this invention is not to be limited to the specific details shown and described herein.

Claims

CLAIMS I claim: 1. A wound healing apparatus for treating a wound, comprising: a plurality of skeletal members; and a biodegradable material supported by said plurality of skeletal members.
2. The wound healing apparatus of claim 1 wherein: said biodegradable material comprises a bioabsorbable fabric; and wherein said plurality of skeletal members and said bioabsorbable fabric form an expandable bag that is deployable from an insertion tube with a plunger.
3. The wound healing apparatus of claim 1 wherein: said biodegradable material comprises a bioabsorbable fabric; and wherein said plurality of skeletal members and said bioabsorbable fabric form a substantially planar structure.
4. The wound healing apparatus of claim 1 wherein at least one of said plurality of skeletal members comprises a conduit for removing fluid from the wound.
5. The wound healing apparatus of claim 4 wherein said conduit is placeable in fluid communication with a suction device to assist in removing fluid from the wound.
6. The wound healing apparatus of claim 4 wherein said conduit is adaptable for injecting medicine into the wound.
7. The wound healing apparatus of claim 1 further comprising at least one sensor connected to at least one of said plurality of skeletal members; wherein said at least one sensor is selected from the group consisting of an oxygen saturation sensor, a carbon dioxide sensor, an electrocardiogram sensor, and a blood pressure sensor.
8. The wound healing apparatus of claim 7 wherein: said at least one sensor comprises a carbon dioxide sensor; and said biodegradable material comprises a PHA material.
9. The wound healing apparatus of claim 1 further comprising a plurality of electrodes connected to at least one of said plurality of skeletal members; said plurality of electrodes being adaptable for providing electrical stimulation to the wound.
10. The wound healing apparatus of claim 1 wherein said plurality of skeletal members comprises a biodegradable material.
11. A wound healing apparatus comprising: an evacuation tube; a plurality of flexible tubes connected to said evacuation tube; a bioabsorbable fabric supported by said plurality of flexible tubes; an insertion tube in which said plurality of flexible tubes and said bioabsorbable fabric are initially disposed; and a plunger operably connected to said plurality of flexible tubes; wherein said insertion tube is insertable into a wound; wherein said plunger is operable for deploying said plurality of flexible tubes and said bioabsorbable fabric from said insertion tube into the wound; wherein said plurality of flexible tubes is adaptable for removing fluid from the wound through said evacuation tube; and wherein said plurality of flexible tubes is removable from the wound after said bioabsorbable fabric is absorbed by the wound.
12. The wound healing apparatus of claim 11 wherein said plurality of flexible tubes and said bioabsorbable fabric form an expandable bag.
13. The wound healing apparatus of claim 11 wherein said evacuation tube is adaptable for connection to a suction device to assist in removing fluid from the wound.
14. The wound healing apparatus of claim 11 further comprising at least one sensor connected to at least one of said plurality of flexible tubes; wherein said at least one sensor is selected from the group consisting of an oxygen saturation sensor, a carbon dioxide sensor, an electrocardiogram sensor, and a blood pressure sensor.
15. The wound healing apparatus of claim 14 wherein: said at least one sensor comprises a carbon dioxide sensor; and said bioabsorbable fabric comprises a PHA material.
16. The wound healing apparatus of claim 11 wherein said evacuation tube and at least one of said plurality of flexible tubes are adaptable for injecting medicine into the wound.
17. The wound healing apparatus of claim 11 wherein said bioabsorbable fabric comprises medicine embedded therein.
18. The wound healing apparatus of claim 11 wherein said plurality of flexible tubes comprises a biodegradable material.
19. The wound healing apparatus of claim 11 further comprising a plurality of electrodes connected to at least one of said plurality of flexible tubes; said plurality of electrodes being adaptable for providing electrical stimulation to the wound.
20. A wound healing apparatus comprising: an evacuation tube; a plurality of flexible tubes connected to said evacuation tube; and a bioabsorbable fabric supported by said plurality of flexible tubes; said apparatus being adaptable for placement in a wound; wherein said plurality of flexible tubes is adaptable for removing fluid from the wound through said evacuation tube; and wherein said plurality of flexible tubes is removable from the wound after said bioabsorbable fabric is absorbed by the wound.
21. The wound healing apparatus of claim 20 wherein said plurality of flexible tubes and said bioabsorbable fabric form a substantially flat structure.
22. The wound healing apparatus of claim 20 wherein said plurality of flexible tubes and said bioabsorbable fabric form a curved structure.
23. The wound healing apparatus of claim 20 wherein said evacuation tube is adaptable for connection to a suction device to assist in removing fluid from the wound.
24. The wound healing apparatus of claim 20 further comprising at least one sensor connected to at least one of said plurality of flexible tubes; wherein said at least one sensor is selected from the group consisting of an oxygen saturation sensor, a carbon dioxide sensor, an electrocardiogram sensor, and a blood pressure sensor.
25. The wound healing apparatus of claim 24 wherein: said at least one sensor comprises a carbon dioxide sensor; and said bioabsorbable fabric comprises a PHA material.
26. The wound healing apparatus of claim 20 wherein said bioabsorbable fabric comprises medicine embedded therein.
27. The wound healing apparatus of claim 20 wherein said evacuation tube and at least one of said plurality of flexible tubes are adaptable for injecting medicine into the wound.
28. The wound healing apparatus of claim 20 wherein said plurality of flexible tubes comprises a biodegradable material.
29. The wound healing apparatus of claim 20 further comprising a plurality of electrodes connected to at least one of said plurality of flexible tubes; said plurality of electrodes being adaptable for providing electrical stimulation to the wound.
30. A method of treating a wound of a patient, comprising the following steps: placing a wound healing apparatus in the wound, said apparatus comprising: a plurality of skeletal members; and a biodegradable material supported by said plurality of skeletal members; and allowing said biodegradable material to be absorbed in the wound.
31. The method of claim 30 wherein at least one of said plurality of skeletal members comprises a conduit, and wherein said method further comprises the step of: removing fluid from the wound through said conduit.
32. The method of claim 31 further comprising the step of: placing said conduit in fluid communication with a suction device.
33. The method of claim 30 wherein at least one of said plurality of skeletal members comprises a conduit, and wherein said method further comprises the step of: injecting medicine into the wound through said conduit.
34. The method of claim 30 wherein said biodegradable material comprises a bioabsorbable fabric, and wherein said plurality of skeletal members and said bioabsorbable fabric form an expandable bag initially disposed within an insertion tube, and wherein said method further comprises the steps of: inserting said insertion tube into the wound; and deploying said expandable bag into the wound.
35. The method of claim 30 wherein said plurality of skeletal members and said biodegradable material form a substantially flat structure.
36. The method of claim 30 wherein said plurality of skeletal members and said biodegradable material form a curved structure.
37. The method of claim 30 wherein said wound healing apparatus further comprises an oxygen saturation sensor connected to at least one of said plurality of skeletal members, and wherein said method further comprises the step of: measuring an oxygen saturation level of blood in the vicinity of the wound with said oxygen saturation sensor.
38. The method of claim 37 further comprising the step of: calculating a heart rate of the patient based on a signal from said oxygen saturation sensor.
39. The method of claim 30 wherein said placing step is performed as part of a surgical procedure.
40. The method of claim 39 wherein said surgical procedure is a "flap and graft" plastic surgery procedure.
41. The method of claim 39 further comprising the step of: closing skin over said apparatus.
42. The method of claim 30 wherein said biodegradable material comprises a PHA material, and wherein said method further comprises the step of: placing a carbon dioxide sensor in the wound to monitor the wound for infection.
43. The method of claim 30 wherein said wound healing apparatus further comprises a plurality of electrodes connected to at least one of said plurality of skeletal members, and wherein said method further comprises the step of: stimulating the wound with electricity through said plurality of electrodes.
44. The method of claim 30 wherein said biodegradable material comprises medicine embedded therein.
45. The method of claim 30 wherein said wound healing apparatus further comprises an ECG sensor connected to said plurality of skeletal members, and wherein said method further comprises the step of: monitoring ECG activity in the vicinity of the wound with said ECG sensor.
46. The method of claim 30 wherein said wound healing apparatus further comprises a pressure transducer connected to said plurality of skeletal members, and wherein said method further comprises the step of: monitoring blood pressure in the vicinity of the wound with said pressure transducer.
47. The method of claim 30 further comprising the step of: removing said plurality of skeletal members from the wound.
48. The method of claim 30 wherein said plurality of skeletal members is made of a biodegradable material, and wherein said metiiod further comprises the step of: allowing said plurality of skeletal members to be absorbed in the wound.
PCT/US2004/029309 2003-09-10 2004-09-09 Wound healing apparatus with bioabsorbable material and suction tubes WO2005025448A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
AT04783527T ATE474535T1 (en) 2003-09-10 2004-09-09 WOUND HEALING DEVICE WITH BIOABSORBABLE MATERIAL AND SUCTION TUBES
DE602004028255T DE602004028255D1 (en) 2003-09-10 2004-09-09 WOUND HEALING EQUIPMENT WITH BIOABSORBABLE MATERIAL AND SUCTION TUBES
EP04783527A EP1663063B1 (en) 2003-09-10 2004-09-09 Wound healing apparatus with bioabsorbable material and suction tubes

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US50179903P 2003-09-10 2003-09-10
US60/501,799 2003-09-10
US10/818,454 US20050065484A1 (en) 2003-09-10 2004-04-05 Wound healing apparatus with bioabsorbable material and suction tubes
US10/818,454 2004-04-05

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WO2005025448A2 true WO2005025448A2 (en) 2005-03-24
WO2005025448A3 WO2005025448A3 (en) 2007-04-12

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009151645A2 (en) * 2008-06-13 2009-12-17 Premco Medical Systems, Inc. Wound treatment apparatus and method
EP2023999B2 (en) 2006-06-02 2016-05-11 KCI Licensing Inc. A wound suction peg apparatus
CN111248943A (en) * 2020-02-11 2020-06-09 刘敏 Intervention device for detecting hydrops in abdominal cavity

Families Citing this family (81)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6458109B1 (en) 1998-08-07 2002-10-01 Hill-Rom Services, Inc. Wound treatment apparatus
US6764462B2 (en) 2000-11-29 2004-07-20 Hill-Rom Services Inc. Wound treatment apparatus
US6824533B2 (en) 2000-11-29 2004-11-30 Hill-Rom Services, Inc. Wound treatment apparatus
JP2004509658A (en) 2000-05-22 2004-04-02 コフィー,アーサー,シー. Combination of small intestinal submucosa and vacuum bandage and its use
US6855135B2 (en) 2000-11-29 2005-02-15 Hill-Rom Services, Inc. Vacuum therapy and cleansing dressing for wounds
US6685681B2 (en) 2000-11-29 2004-02-03 Hill-Rom Services, Inc. Vacuum therapy and cleansing dressing for wounds
EP1450878A1 (en) 2001-10-11 2004-09-01 Hill-Rom Services, Inc. Waste container for negative pressure therapy
US6648862B2 (en) * 2001-11-20 2003-11-18 Spheric Products, Ltd. Personally portable vacuum desiccator
WO2003057307A1 (en) 2001-12-26 2003-07-17 Hill-Rom Services, Inc. Wound vacuum therapy dressing kit
US7534927B2 (en) 2001-12-26 2009-05-19 Hill-Rom Services, Inc. Vacuum bandage packing
EP1478313B2 (en) 2001-12-26 2018-03-07 KCI Medical Resources Vented vacuum bandage
US8168848B2 (en) * 2002-04-10 2012-05-01 KCI Medical Resources, Inc. Access openings in vacuum bandage
US7896856B2 (en) * 2002-08-21 2011-03-01 Robert Petrosenko Wound packing for preventing wound closure
GB0224986D0 (en) 2002-10-28 2002-12-04 Smith & Nephew Apparatus
GB0325130D0 (en) * 2003-10-28 2003-12-03 Smith & Nephew Apparatus with scaffold
US7790945B1 (en) 2004-04-05 2010-09-07 Kci Licensing, Inc. Wound dressing with absorption and suction capabilities
GB0424046D0 (en) * 2004-10-29 2004-12-01 Smith & Nephew Apparatus
US8529548B2 (en) 2004-04-27 2013-09-10 Smith & Nephew Plc Wound treatment apparatus and method
GB0409446D0 (en) 2004-04-28 2004-06-02 Smith & Nephew Apparatus
US7824384B2 (en) 2004-08-10 2010-11-02 Kci Licensing, Inc. Chest tube drainage system
GB0524027D0 (en) * 2005-11-25 2006-01-04 Smith & Nephew Fibrous dressing
KR101045751B1 (en) * 2006-02-06 2011-06-30 케이씨아이 라이센싱 인코포레이티드 Systems and methods for improved connection to wound dressings in conjunction with reduced pressure wound treatment systems
US8235939B2 (en) * 2006-02-06 2012-08-07 Kci Licensing, Inc. System and method for purging a reduced pressure apparatus during the administration of reduced pressure treatment
US9456860B2 (en) * 2006-03-14 2016-10-04 Kci Licensing, Inc. Bioresorbable foaming tissue dressing
US20070219585A1 (en) 2006-03-14 2007-09-20 Cornet Douglas A System for administering reduced pressure treatment having a manifold with a primary flow passage and a blockage prevention member
US20080033324A1 (en) * 2006-03-14 2008-02-07 Cornet Douglas A System for administering reduced pressure treatment having a manifold with a primary flow passage and a blockage prevention member
US8338402B2 (en) * 2006-05-12 2012-12-25 Smith & Nephew Plc Scaffold
CA2872297C (en) 2006-09-28 2016-10-11 Smith & Nephew, Inc. Portable wound therapy system
US7931651B2 (en) 2006-11-17 2011-04-26 Wake Lake University Health Sciences External fixation assembly and method of use
US8377016B2 (en) 2007-01-10 2013-02-19 Wake Forest University Health Sciences Apparatus and method for wound treatment employing periodic sub-atmospheric pressure
US8267908B2 (en) * 2007-02-09 2012-09-18 Kci Licensing, Inc. Delivery tube, system, and method for storing liquid from a tissue site
RU2459636C2 (en) * 2007-02-09 2012-08-27 КейСиАй Лайсензинг Инк. Apparatus and method for treating tissue region by applying low pressure
BRPI0817544A2 (en) 2007-10-10 2017-05-02 Univ Wake Forest Health Sciences apparatus for treating damaged spinal cord tissue
US20130096518A1 (en) * 2007-12-06 2013-04-18 Smith & Nephew Plc Wound filling apparatuses and methods
US11253399B2 (en) * 2007-12-06 2022-02-22 Smith & Nephew Plc Wound filling apparatuses and methods
GB2455962A (en) 2007-12-24 2009-07-01 Ethicon Inc Reinforced adhesive backing sheet, for plaster
DK2242522T3 (en) 2008-01-08 2012-06-18 Bluesky Medical Group Inc Wound treatment with uninterrupted variable pressure and methods for controlling it
US8267960B2 (en) 2008-01-09 2012-09-18 Wake Forest University Health Sciences Device and method for treating central nervous system pathology
US8372049B2 (en) 2008-03-05 2013-02-12 Kci Licensing, Inc. Dressing and method for applying reduced pressure to and collecting and storing fluid from a tissue site
US9033942B2 (en) 2008-03-07 2015-05-19 Smith & Nephew, Inc. Wound dressing port and associated wound dressing
US8945030B2 (en) 2008-03-12 2015-02-03 Bluesky Medical Group, Inc. Negative pressure dressing and method of using same
WO2010009294A1 (en) 2008-07-18 2010-01-21 Wake Forest University Heath Sciences Apparatus and method for cardiac tissue modulation by topical application of vacuum to minimize cell death and damage
US8406865B2 (en) * 2008-09-30 2013-03-26 Covidien Lp Bioimpedance system and sensor and technique for using the same
CA2746525C (en) * 2008-12-31 2017-12-12 Kci Licensing, Inc. Manifolds, systems, and methods for administering reduced pressure to a subcutaneous tissue site
DE102009017960B4 (en) * 2009-04-20 2014-04-30 Iskia Gmbh & Co.Kg Surface drainage for the removal of wound secretions from large wounds and body cavities
US20100324516A1 (en) 2009-06-18 2010-12-23 Tyco Healthcare Group Lp Apparatus for Vacuum Bridging and/or Exudate Collection
EP2461863B1 (en) 2009-08-05 2016-07-27 Covidien LP Surgical wound dressing incorporating connected hydrogel beads having an embedded electrode therein
US8529526B2 (en) * 2009-10-20 2013-09-10 Kci Licensing, Inc. Dressing reduced-pressure indicators, systems, and methods
WO2011087871A2 (en) 2009-12-22 2011-07-21 Smith & Nephew, Inc. Apparatuses and methods for negative pressure wound therapy
US8377018B2 (en) 2009-12-23 2013-02-19 Kci Licensing, Inc. Reduced-pressure, multi-orientation, liquid-collection canister
US8814842B2 (en) * 2010-03-16 2014-08-26 Kci Licensing, Inc. Delivery-and-fluid-storage bridges for use with reduced-pressure systems
USRE48117E1 (en) 2010-05-07 2020-07-28 Smith & Nephew, Inc. Apparatuses and methods for negative pressure wound therapy
US8480710B2 (en) 2010-11-04 2013-07-09 Covidien Lp Wound closure device including suction step sleeve
WO2012087376A1 (en) 2010-12-22 2012-06-28 Smith & Nephew, Inc. Apparatuses and methods for negative pressure wound therapy
USD714433S1 (en) 2010-12-22 2014-09-30 Smith & Nephew, Inc. Suction adapter
GB2488749A (en) 2011-01-31 2012-09-12 Systagenix Wound Man Ip Co Bv Laminated silicone coated wound dressing
MX364446B (en) 2011-04-15 2019-04-26 Univ Massachusetts Surgical cavity drainage and closure system.
GB201106491D0 (en) 2011-04-15 2011-06-01 Systagenix Wound Man Ip Co Bv Patterened silicone coating
JP6320930B2 (en) 2011-12-16 2018-05-09 ケーシーアイ ライセンシング インコーポレイテッド Peelable medical drape
US10940047B2 (en) 2011-12-16 2021-03-09 Kci Licensing, Inc. Sealing systems and methods employing a hybrid switchable drape
EP4279094A3 (en) 2012-11-16 2024-02-28 3M Innovative Properties Company Medical drape with pattern adhesive layers
GB201222770D0 (en) 2012-12-18 2013-01-30 Systagenix Wound Man Ip Co Bv Wound dressing with adhesive margin
EP3038667B1 (en) 2013-08-26 2019-10-09 KCI Licensing, Inc. Dressing interface with moisture controlling feature and sealing function
US10946124B2 (en) 2013-10-28 2021-03-16 Kci Licensing, Inc. Hybrid sealing tape
EP3513773A1 (en) 2013-10-30 2019-07-24 KCI Licensing, Inc. Condensate absorbing and dissipating system
US10016544B2 (en) 2013-10-30 2018-07-10 Kci Licensing, Inc. Dressing with differentially sized perforations
WO2015065616A1 (en) 2013-10-30 2015-05-07 Kci Licensing, Inc. Dressing with sealing and retention intereface
EP3062833B1 (en) 2013-10-30 2019-04-17 KCI Licensing, Inc. Absorbent conduit and system
US10398441B2 (en) 2013-12-20 2019-09-03 Terumo Corporation Vascular occlusion
WO2015130471A1 (en) 2014-02-28 2015-09-03 Kci Licensing, Inc. Hybrid drape having a gel-coated perforated mesh
US11026844B2 (en) 2014-03-03 2021-06-08 Kci Licensing, Inc. Low profile flexible pressure transmission conduit
WO2015168681A1 (en) 2014-05-02 2015-11-05 Kci Licensing, Inc. Fluid storage devices, systems, and methods
EP3854361B8 (en) 2014-06-05 2024-03-27 Solventum Intellectual Properties Company Dressing with fluid acquisition and distribution characteristics
EP3233001B1 (en) 2014-12-17 2020-06-17 KCI Licensing, Inc. Dressing with offloading capability
EP3294245B1 (en) 2015-05-08 2019-09-04 KCI Licensing, Inc. Low acuity dressing with integral pump
US11096830B2 (en) 2015-09-01 2021-08-24 Kci Licensing, Inc. Dressing with increased apposition force
WO2017048866A1 (en) 2015-09-17 2017-03-23 Kci Licensing, Inc. Hybrid silicone and acrylic adhesive cover for use with wound treatment
WO2019059893A1 (en) * 2017-09-19 2019-03-28 Steel Trap Enterprises, Llc Negative pressure therapy unit and method
US20200261276A1 (en) * 2017-11-08 2020-08-20 University Of Massachusetts Post-Operative Hybrid Dressing To Optimize Skin-Grafting Procedures In Reconstructive Surgery
GB201811449D0 (en) 2018-07-12 2018-08-29 Smith & Nephew Apparatuses and methods for negative pressure wound therapy
US11564692B2 (en) 2018-11-01 2023-01-31 Terumo Corporation Occlusion systems

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003028786A2 (en) 2001-09-28 2003-04-10 Jan Otto Solem A method, a device, and a system for organ reconditioning and a device for preserving an internal bodyorgan

Family Cites Families (100)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2547758A (en) * 1949-01-05 1951-04-03 Wilmer B Keeling Instrument for treating the male urethra
US2632443A (en) * 1949-04-18 1953-03-24 Eleanor P Lesher Surgical dressing
US2969057A (en) * 1957-11-04 1961-01-24 Brady Co W H Nematodic swab
US3026874A (en) * 1959-11-06 1962-03-27 Robert C Stevens Wound shield
US3089492A (en) * 1961-05-11 1963-05-14 Owens Neal Wet surgical dressing
US3367332A (en) * 1965-08-27 1968-02-06 Gen Electric Product and process for establishing a sterile area of skin
US3568675A (en) * 1968-08-30 1971-03-09 Clyde B Harvey Fistula and penetrating wound dressing
BE789293Q (en) * 1970-12-07 1973-01-15 Parke Davis & Co MEDICO-SURGICAL DRESSING FOR BURNS AND SIMILAR LESIONS
DE2527706A1 (en) * 1975-06-21 1976-12-30 Hanfried Dr Med Weigand DEVICE FOR THE INTRODUCTION OF CONTRAST AGENTS INTO AN ARTIFICIAL INTESTINAL OUTLET
NL7710909A (en) * 1976-10-08 1978-04-11 Smith & Nephew COMPOSITE STRAPS.
US4080970A (en) * 1976-11-17 1978-03-28 Miller Thomas J Post-operative combination dressing and internal drain tube with external shield and tube connector
US4139004A (en) * 1977-02-17 1979-02-13 Gonzalez Jr Harry Bandage apparatus for treating burns
US4184510A (en) * 1977-03-15 1980-01-22 Fibra-Sonics, Inc. Valued device for controlling vacuum in surgery
US4256109A (en) * 1978-07-10 1981-03-17 Nichols Robert L Shut off valve for medical suction apparatus
SE414994B (en) * 1978-11-28 1980-09-01 Landstingens Inkopscentral VENKATETERFORBAND
BR7908937A (en) * 1978-12-06 1981-06-30 Svedman Paul DEVICE FOR TREATING FABRICS, FOR EXAMPLE, SKIN
US4261360A (en) * 1979-11-05 1981-04-14 Urethral Devices Research, Inc. Transurethral irrigation pressure controller
US4261363A (en) * 1979-11-09 1981-04-14 C. R. Bard, Inc. Retention clips for body fluid drains
US4569348A (en) * 1980-02-22 1986-02-11 Velcro Usa Inc. Catheter tube holder strap
US4333468A (en) * 1980-08-18 1982-06-08 Geist Robert W Mesentery tube holder apparatus
US4373519A (en) * 1981-06-26 1983-02-15 Minnesota Mining And Manufacturing Company Composite wound dressing
DE3146266A1 (en) * 1981-11-21 1983-06-01 B. Braun Melsungen Ag, 3508 Melsungen COMBINED DEVICE FOR A MEDICAL SUCTION DRAINAGE
US4444545A (en) * 1982-04-08 1984-04-24 Sanders David F Pump control system
US4525374A (en) * 1984-02-27 1985-06-25 Manresa, Inc. Treating hydrophobic filters to render them hydrophilic
US4897081A (en) * 1984-05-25 1990-01-30 Thermedics Inc. Percutaneous access device
US5002541A (en) * 1984-06-19 1991-03-26 Martin And Associates, Inc. Method and device for removing and collecting urine
US5215522A (en) * 1984-07-23 1993-06-01 Ballard Medical Products Single use medical aspirating device and method
GB8419745D0 (en) * 1984-08-02 1984-09-05 Smith & Nephew Ass Wound dressing
US4826494A (en) * 1984-11-09 1989-05-02 Stryker Corporation Vacuum wound drainage system
US4655754A (en) * 1984-11-09 1987-04-07 Stryker Corporation Vacuum wound drainage system and lipids baffle therefor
GB2176401A (en) * 1985-06-12 1986-12-31 Vernon Carus Ltd Wound dressing
US4640688A (en) * 1985-08-23 1987-02-03 Mentor Corporation Urine collection catheter
US4733659A (en) * 1986-01-17 1988-03-29 Seton Company Foam bandage
US4820291A (en) * 1986-02-27 1989-04-11 Nippon Medical Supply Corporation Urinary applicance
US4838883A (en) * 1986-03-07 1989-06-13 Nissho Corporation Urine-collecting device
JPS62281965A (en) * 1986-05-29 1987-12-07 テルモ株式会社 Catheter and catheter fixing member
GB8621884D0 (en) * 1986-09-11 1986-10-15 Bard Ltd Catheter applicator
US4743232A (en) * 1986-10-06 1988-05-10 The Clinipad Corporation Package assembly for plastic film bandage
US4930997A (en) * 1987-08-19 1990-06-05 Bennett Alan N Portable medical suction device
US5176663A (en) * 1987-12-02 1993-01-05 Pal Svedman Dressing having pad with compressibility limiting elements
US4906240A (en) * 1988-02-01 1990-03-06 Matrix Medica, Inc. Adhesive-faced porous absorbent sheet and method of making same
US4985019A (en) * 1988-03-11 1991-01-15 Michelson Gary K X-ray marker
US5374261A (en) * 1990-07-24 1994-12-20 Yoon; Inbae Multifunctional devices for use in endoscopic surgical procedures and methods-therefor
US4919654A (en) * 1988-08-03 1990-04-24 Kalt Medical Corporation IV clamp with membrane
DE69017479T2 (en) * 1989-01-16 1995-07-13 Roussel Uclaf Azabicyclohepten derivatives and their salts, processes for their preparation, their use as medicaments and preparations containing them.
IE901130A1 (en) * 1989-03-30 1991-02-13 Abbott Lab Suction drainage infection control system
US5527293A (en) * 1989-04-03 1996-06-18 Kinetic Concepts, Inc. Fastening system and method
US5100396A (en) * 1989-04-03 1992-03-31 Zamierowski David S Fluidic connection system and method
JP2719671B2 (en) * 1989-07-11 1998-02-25 日本ゼオン株式会社 Wound dressing
IL91918A0 (en) * 1989-10-06 1990-06-10 Rosenberg Lior Fluid drain system for wounds
US4996128A (en) * 1990-03-12 1991-02-26 Nova Manufacturing, Inc. Rechargeable battery
US5092858A (en) * 1990-03-20 1992-03-03 Becton, Dickinson And Company Liquid gelling agent distributor device
US5211639A (en) * 1990-05-30 1993-05-18 Wilk Peter J Evacuator assembly
DE4037931A1 (en) * 1990-11-23 1992-05-27 Detlef Dr Ing Behrend Swab for resorbable protection of wound cavity - with soft foam body in soft foam casing with embedded resorbable hollow fibres connected to tube
US5180375A (en) * 1991-05-02 1993-01-19 Feibus Miriam H Woven surgical drain and woven surgical sponge
US5278100A (en) * 1991-11-08 1994-01-11 Micron Technology, Inc. Chemical vapor deposition technique for depositing titanium silicide on semiconductor wafers
US5279550A (en) * 1991-12-19 1994-01-18 Gish Biomedical, Inc. Orthopedic autotransfusion system
AU4102493A (en) * 1992-03-16 1994-11-08 Envirosurgical, Inc. Surgery plume filter device and method of filtering
US5419769A (en) * 1992-10-23 1995-05-30 Smiths Industries Medical Systems, Inc. Suction systems
CA2132657C (en) * 1993-10-05 2005-12-06 Marjory A. Kadash Trimmable wound dressing
US5607388A (en) * 1994-06-16 1997-03-04 Hercules Incorporated Multi-purpose wound dressing
US5733337A (en) * 1995-04-07 1998-03-31 Organogenesis, Inc. Tissue repair fabric
US5741237A (en) * 1995-04-10 1998-04-21 Walker; Kenneth Gordon System for disposal of fluids
GB9521397D0 (en) * 1995-10-18 1995-12-20 Summit Medical Ltd Wound drainage system
US6090063A (en) * 1995-12-01 2000-07-18 C. R. Bard, Inc. Device, system and method for implantation of filaments and particles in the body
US5628735A (en) * 1996-01-11 1997-05-13 Skow; Joseph I. Surgical device for wicking and removing fluid
US6949116B2 (en) * 1996-05-08 2005-09-27 Carag Ag Device for plugging an opening such as in a wall of a hollow or tubular organ including biodegradable elements
FR2761891B1 (en) * 1997-04-14 1999-09-24 Synthelabo FLEXIBLE SURGICAL DRAIN WITH A PLURALITY OF INDIVIDUAL DUCTS
CN1116904C (en) * 1997-06-18 2003-08-06 独立行政法人农业生物资源研究所 Wound covering material containing silk fibroin and silk sericin as main components and process for producing the same
GB9719520D0 (en) * 1997-09-12 1997-11-19 Kci Medical Ltd Surgical drape and suction heads for wound treatment
US6165193A (en) * 1998-07-06 2000-12-26 Microvention, Inc. Vascular embolization with an expansible implant
US6356782B1 (en) * 1998-12-24 2002-03-12 Vivant Medical, Inc. Subcutaneous cavity marking device and method
US6428747B1 (en) * 1998-12-30 2002-08-06 Cardiovention, Inc. Integrated extracorporeal blood oxygenator, pump and heat exchanger system
US6126675A (en) * 1999-01-11 2000-10-03 Ethicon, Inc. Bioabsorbable device and method for sealing vascular punctures
EP1159015A1 (en) * 1999-03-04 2001-12-05 Tepha, Inc. Bioabsorbable, biocompatible polymers for tissue engineering
US6368563B1 (en) * 1999-03-12 2002-04-09 Integ, Inc. Collection well for body fluid tester
US20030040809A1 (en) * 1999-03-20 2003-02-27 Helmut Goldmann Flat implant for use in surgery
US6548569B1 (en) * 1999-03-25 2003-04-15 Metabolix, Inc. Medical devices and applications of polyhydroxyalkanoate polymers
US6994702B1 (en) * 1999-04-06 2006-02-07 Kci Licensing, Inc. Vacuum assisted closure pad with adaptation for phototherapy
US6856821B2 (en) * 2000-05-26 2005-02-15 Kci Licensing, Inc. System for combined transcutaneous blood gas monitoring and vacuum assisted wound closure
US6695823B1 (en) * 1999-04-09 2004-02-24 Kci Licensing, Inc. Wound therapy device
US6210360B1 (en) * 1999-05-26 2001-04-03 Carl Cheung Tung Kong Fluid displacement pumps
US6333029B1 (en) * 1999-06-30 2001-12-25 Ethicon, Inc. Porous tissue scaffoldings for the repair of regeneration of tissue
US6536291B1 (en) * 1999-07-02 2003-03-25 Weatherford/Lamb, Inc. Optical flow rate measurement using unsteady pressures
US6179804B1 (en) * 1999-08-18 2001-01-30 Oxypatch, Llc Treatment apparatus for wounds
US6557704B1 (en) * 1999-09-08 2003-05-06 Kci Licensing, Inc. Arrangement for portable pumping unit
US6352525B1 (en) * 1999-09-22 2002-03-05 Akio Wakabayashi Portable modular chest drainage system
US6566575B1 (en) * 2000-02-15 2003-05-20 3M Innovative Properties Company Patterned absorbent article for wound dressing
US6523681B1 (en) * 2000-02-25 2003-02-25 Technicor, Inc. Absorbent/adsorbent pads
GB0011202D0 (en) * 2000-05-09 2000-06-28 Kci Licensing Inc Abdominal wound dressing
US6685681B2 (en) * 2000-11-29 2004-02-03 Hill-Rom Services, Inc. Vacuum therapy and cleansing dressing for wounds
US6656488B2 (en) * 2001-04-11 2003-12-02 Ethicon Endo-Surgery, Inc. Bioabsorbable bag containing bioabsorbable materials of different bioabsorption rates for tissue engineering
US6855153B2 (en) * 2001-05-01 2005-02-15 Vahid Saadat Embolic balloon
AU2002315027A1 (en) * 2001-05-15 2002-11-25 Children's Medical Center Corporation Methods and apparatus for application of micro-mechanical forces to tissues
US6860872B2 (en) * 2001-08-20 2005-03-01 Joseph Von Teichert Safety syringe/catheter
US6693180B2 (en) * 2002-04-04 2004-02-17 China Textile Institute Composite sponge wound dressing made of β-Chitin and Chitosan and method for producing the same
US7846141B2 (en) * 2002-09-03 2010-12-07 Bluesky Medical Group Incorporated Reduced pressure treatment system
US6840960B2 (en) * 2002-09-27 2005-01-11 Stephen K. Bubb Porous implant system and treatment method
US7361184B2 (en) * 2003-09-08 2008-04-22 Joshi Ashok V Device and method for wound therapy
US7182758B2 (en) * 2003-11-17 2007-02-27 Mccraw John B Apparatus and method for drainage

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003028786A2 (en) 2001-09-28 2003-04-10 Jan Otto Solem A method, a device, and a system for organ reconditioning and a device for preserving an internal bodyorgan

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2023999B2 (en) 2006-06-02 2016-05-11 KCI Licensing Inc. A wound suction peg apparatus
WO2009151645A2 (en) * 2008-06-13 2009-12-17 Premco Medical Systems, Inc. Wound treatment apparatus and method
WO2009151645A3 (en) * 2008-06-13 2010-04-22 Premco Medical Systems, Inc. Wound treatment apparatus and method
US8480641B2 (en) 2008-06-13 2013-07-09 Premco Medical Systems, Inc. Negative pressure wound treatment apparatus and method
CN111248943A (en) * 2020-02-11 2020-06-09 刘敏 Intervention device for detecting hydrops in abdominal cavity
CN111248943B (en) * 2020-02-11 2022-09-02 荆州市中心医院(长江大学附属荆州医院) Intervention device for detecting hydrops in abdominal cavity

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