WO2005028636A3 - Novel cbh1 homologs and variant cbh1 cellulases - Google Patents

Novel cbh1 homologs and variant cbh1 cellulases Download PDF

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Publication number
WO2005028636A3
WO2005028636A3 PCT/US2004/008520 US2004008520W WO2005028636A3 WO 2005028636 A3 WO2005028636 A3 WO 2005028636A3 US 2004008520 W US2004008520 W US 2004008520W WO 2005028636 A3 WO2005028636 A3 WO 2005028636A3
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WO
WIPO (PCT)
Prior art keywords
cbh1
homologs
cellulases
variant
novel
Prior art date
Application number
PCT/US2004/008520
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French (fr)
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WO2005028636A2 (en
WO2005028636A8 (en
Inventor
Frits Goedegebuur
Peter Gualfetti
Colin Mitchinson
Paulien Neefe
Original Assignee
Genencor Int
Frits Goedegebuur
Peter Gualfetti
Colin Mitchinson
Paulien Neefe
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genencor Int, Frits Goedegebuur, Peter Gualfetti, Colin Mitchinson, Paulien Neefe filed Critical Genencor Int
Priority to CN2004800075623A priority Critical patent/CN1898381B/en
Priority to CA2519760A priority patent/CA2519760C/en
Priority to EP04809323A priority patent/EP1606392A4/en
Priority to JP2006509249A priority patent/JP2007534294A/en
Publication of WO2005028636A2 publication Critical patent/WO2005028636A2/en
Publication of WO2005028636A8 publication Critical patent/WO2005028636A8/en
Publication of WO2005028636A3 publication Critical patent/WO2005028636A3/en

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2405—Glucanases
    • C12N9/2434—Glucanases acting on beta-1,4-glucosidic bonds
    • C12N9/2437—Cellulases (3.2.1.4; 3.2.1.74; 3.2.1.91; 3.2.1.150)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01091—Cellulose 1,4-beta-cellobiosidase (3.2.1.91)

Abstract

Disclosed are a number of homologs and variants of Hypocrea jecorina Cel7A (formerly Trichoderma reesei cellobiohydrolase I or CBH1), nucleic acids encoding the same and methods for producing the same. The homologs and variant cellulases have the amino acid sequence of a glycosyl hydrolase of family 7A wherein one or more amino acid residues are substituted and/or deleted.
PCT/US2004/008520 2003-03-21 2004-03-19 Novel cbh1 homologs and variant cbh1 cellulases WO2005028636A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
CN2004800075623A CN1898381B (en) 2003-03-21 2004-03-19 Novel cbh1 homologs and variant cbh1 cellulases
CA2519760A CA2519760C (en) 2003-03-21 2004-03-19 Cbh1 homologs and variant cbh1 cellulases
EP04809323A EP1606392A4 (en) 2003-03-21 2004-03-19 Novel cbh1 homologs and variant cbh1 cellulases
JP2006509249A JP2007534294A (en) 2003-03-21 2004-03-19 CBH1 homologues and mutant CBH1 cellulases

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US45636803P 2003-03-21 2003-03-21
US60/456,368 2003-03-21
US45869603P 2003-03-27 2003-03-27
US60/458,696 2003-03-27

Publications (3)

Publication Number Publication Date
WO2005028636A2 WO2005028636A2 (en) 2005-03-31
WO2005028636A8 WO2005028636A8 (en) 2005-05-06
WO2005028636A3 true WO2005028636A3 (en) 2006-08-17

Family

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Family Applications (1)

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PCT/US2004/008520 WO2005028636A2 (en) 2003-03-21 2004-03-19 Novel cbh1 homologs and variant cbh1 cellulases

Country Status (6)

Country Link
US (3) US7452707B2 (en)
EP (3) EP2298876A1 (en)
JP (2) JP2007534294A (en)
CN (1) CN1898381B (en)
CA (2) CA2770976C (en)
WO (1) WO2005028636A2 (en)

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