WO2005034624A3 - Microfabricated compositions and processes for engineering tissues containing multiple cell types - Google Patents
Microfabricated compositions and processes for engineering tissues containing multiple cell types Download PDFInfo
- Publication number
- WO2005034624A3 WO2005034624A3 PCT/US2004/016059 US2004016059W WO2005034624A3 WO 2005034624 A3 WO2005034624 A3 WO 2005034624A3 US 2004016059 W US2004016059 W US 2004016059W WO 2005034624 A3 WO2005034624 A3 WO 2005034624A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- processes
- cell types
- containing multiple
- multiple cell
- tissues containing
- Prior art date
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Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/0068—General culture methods using substrates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/0062—General methods for three-dimensional culture
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0697—Artificial constructs associating cells of different lineages, e.g. tissue equivalents
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B33—ADDITIVE MANUFACTURING TECHNOLOGY
- B33Y—ADDITIVE MANUFACTURING, i.e. MANUFACTURING OF THREE-DIMENSIONAL [3-D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVE AGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3-D PRINTING, STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING
- B33Y80/00—Products made by additive manufacturing
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/30—Synthetic polymers
- C12N2533/40—Polyhydroxyacids, e.g. polymers of glycolic or lactic acid (PGA, PLA, PLGA); Bioresorbable polymers
Abstract
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP04809403A EP1636351A4 (en) | 2003-05-21 | 2004-05-21 | Microfabricated compositions and processes for engineering tissues containing multiple cell types |
US10/557,081 US7960166B2 (en) | 2003-05-21 | 2004-05-21 | Microfabricated compositions and processes for engineering tissues containing multiple cell types |
US13/156,675 US8357528B2 (en) | 2003-05-21 | 2011-06-09 | Microfabricated compositions and processes for engineering tissues containing multiple cell types |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US47223003P | 2003-05-21 | 2003-05-21 | |
US60/472,230 | 2003-05-21 |
Related Child Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US10/557,081 A-371-Of-International US7960166B2 (en) | 2003-05-21 | 2004-05-21 | Microfabricated compositions and processes for engineering tissues containing multiple cell types |
US13/156,675 Continuation US8357528B2 (en) | 2003-05-21 | 2011-06-09 | Microfabricated compositions and processes for engineering tissues containing multiple cell types |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2005034624A2 WO2005034624A2 (en) | 2005-04-21 |
WO2005034624A3 true WO2005034624A3 (en) | 2005-08-25 |
Family
ID=34434805
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2004/016059 WO2005034624A2 (en) | 2003-05-21 | 2004-05-21 | Microfabricated compositions and processes for engineering tissues containing multiple cell types |
Country Status (3)
Country | Link |
---|---|
US (2) | US7960166B2 (en) |
EP (1) | EP1636351A4 (en) |
WO (1) | WO2005034624A2 (en) |
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US20090234332A1 (en) * | 2008-03-17 | 2009-09-17 | The Charles Stark Draper Laboratory, Inc | Artificial microvascular device and methods for manufacturing and using the same |
US8685432B2 (en) * | 2008-03-25 | 2014-04-01 | University Of Utah Research Foundation | Controlled release tissue graft combination biomaterials |
US8647861B2 (en) * | 2008-07-16 | 2014-02-11 | Children's Medical Center Corporation | Organ mimic device with microchannels and methods of use and manufacturing thereof |
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US20110082563A1 (en) * | 2009-10-05 | 2011-04-07 | The Charles Stark Draper Laboratory, Inc. | Microscale multiple-fluid-stream bioreactor for cell culture |
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US8414654B1 (en) * | 2011-11-23 | 2013-04-09 | Amendia, Inc. | Bone implants and method of manufacture |
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US10107726B2 (en) | 2016-03-16 | 2018-10-23 | Cellmax, Ltd. | Collection of suspended cells using a transferable membrane |
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Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5518680A (en) * | 1993-10-18 | 1996-05-21 | Massachusetts Institute Of Technology | Tissue regeneration matrices by solid free form fabrication techniques |
US5665596A (en) * | 1995-07-31 | 1997-09-09 | Becton, Dickinson And Company | Device for cell co-culture and method for its use in culturing cells |
US6139574A (en) * | 1993-10-18 | 2000-10-31 | Children's Medical Center Corporation | Vascularized tissue regeneration matrices formed by solid free form fabrication techniques |
US6143293A (en) * | 1998-03-26 | 2000-11-07 | Carnegie Mellon | Assembled scaffolds for three dimensional cell culturing and tissue generation |
US20020182241A1 (en) * | 2001-01-02 | 2002-12-05 | Borenstein Jeffrey T. | Tissue engineering of three-dimensional vascularized using microfabricated polymer assembly technology |
Family Cites Families (92)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3907687A (en) | 1968-12-07 | 1975-09-23 | Baxter Laboratories Inc | Plate dialyzer |
US3684097A (en) | 1970-07-02 | 1972-08-15 | Gen Electric | Blood component exchange device |
US3839204A (en) | 1972-04-27 | 1974-10-01 | Gen Electric | Integral blood heat and component exchange device and two flow path membrane blood gas exchanger |
FR2197565B1 (en) | 1972-08-30 | 1975-03-07 | Rhone Poulenc Ind | |
US3864097A (en) * | 1973-01-15 | 1975-02-04 | Universal Oil Prod Co | Process for converting cellulose |
US3892533A (en) | 1973-03-02 | 1975-07-01 | Sci Med | Oxygenator gas distribution header |
NL7310808A (en) | 1973-08-06 | 1975-02-10 | Josef Augustinus Elizabeth Spa | DEVICE FOR EXCHANGE OF SUBSTANCES BETWEEN TWO ON EACH SIDE OF A MEMBRANE |
US4008047A (en) | 1974-12-26 | 1977-02-15 | North Star Research Institute | Blood compatible polymers for blood oxygenation devices |
DE2622684B2 (en) | 1976-05-21 | 1979-03-15 | Licentia Patent-Verwaltungs-Gmbh, 6000 Frankfurt | Membrane exchanger |
US4191182A (en) | 1977-09-23 | 1980-03-04 | Hemotherapy Inc. | Method and apparatus for continuous plasmaphersis |
US4229290A (en) | 1978-03-14 | 1980-10-21 | Raj Ghen M G | Compact low surface area dialyzer method and apparatus |
GB2072047B (en) | 1979-08-21 | 1984-03-14 | Lidorenko N S | Gas-permeable membrane method of making it and blood oxygenator based on the use thereof |
ATE28797T1 (en) | 1982-12-07 | 1987-08-15 | Brian John Bellhouse | DEVICE FOR TRANSFER WITH A MEMBRANE. |
US4980068A (en) | 1983-08-15 | 1990-12-25 | Lavender Ardis R | System, apparatus and method for continuously fractionating blood in situ |
US5266480A (en) | 1986-04-18 | 1993-11-30 | Advanced Tissue Sciences, Inc. | Three-dimensional skin culture system |
US5863531A (en) | 1986-04-18 | 1999-01-26 | Advanced Tissue Sciences, Inc. | In vitro preparation of tubular tissue structures by stromal cell culture on a three-dimensional framework |
JPH0342927Y2 (en) | 1987-02-09 | 1991-09-09 | ||
IT1202689B (en) | 1987-03-25 | 1989-02-09 | Franco Maria Montevecchi | PROCEDURE AND DEVICE FOR THE EXTRACORPOREAL BLOOD CIRCULATION AND FOR CARDIOVASCULAR ASSISTANCE |
US5225161A (en) | 1988-10-20 | 1993-07-06 | Baxter International Inc. | Integrated membrane blood oxygenator/heat exchanger |
US5316724A (en) | 1989-03-31 | 1994-05-31 | Baxter International Inc. | Multiple blood path membrane oxygenator |
US5204055A (en) | 1989-12-08 | 1993-04-20 | Massachusetts Institute Of Technology | Three-dimensional printing techniques |
US5061620A (en) | 1990-03-30 | 1991-10-29 | Systemix, Inc. | Human hematopoietic stem cell |
US5486359A (en) | 1990-11-16 | 1996-01-23 | Osiris Therapeutics, Inc. | Human mesenchymal stem cells |
US5222982A (en) | 1991-02-11 | 1993-06-29 | Ommaya Ayub K | Spinal fluid driven artificial organ |
US5263924A (en) | 1991-09-25 | 1993-11-23 | Baxter International Inc. | Integrated low priming volume centrifugal pump and membrane oxygenator |
CA2074671A1 (en) | 1991-11-04 | 1993-05-05 | Thomas Bormann | Device and method for separating plasma from a biological fluid |
US5549674A (en) | 1992-03-02 | 1996-08-27 | The Regents Of The University Of Michigan | Methods and compositions of a bioartificial kidney suitable for use in vivo or ex vivo |
US5849553A (en) | 1992-07-27 | 1998-12-15 | California Institute Of Technology | Mammalian multipotent neural stem cells |
JPH06237992A (en) | 1993-02-15 | 1994-08-30 | Terumo Corp | Heat and gas exchanger |
US5308356A (en) | 1993-02-25 | 1994-05-03 | Blackshear Jr Perry L | Passive perfusion angioplasty catheter |
CA2119064A1 (en) | 1993-03-17 | 1994-09-18 | Richard A. Berg | Dermal-epidermal in vitro test system |
DE4320198C1 (en) | 1993-06-18 | 1994-07-14 | Fresenius Ag | Blood gas exchange appts. |
US6200802B1 (en) | 1993-10-08 | 2001-03-13 | Arch Development Corporation | Human peroxisome proliferator activated receptor gamma: compositions and methods |
US5626759A (en) | 1994-08-01 | 1997-05-06 | Regents Of The University Of Colorado | Blood treatment device with moving membrane |
US5843780A (en) | 1995-01-20 | 1998-12-01 | Wisconsin Alumni Research Foundation | Primate embryonic stem cells |
US7008634B2 (en) | 1995-03-03 | 2006-03-07 | Massachusetts Institute Of Technology | Cell growth substrates with tethered cell growth effector molecules |
BE1009306A5 (en) | 1995-04-28 | 1997-02-04 | Baxter Int | Bioreactor. |
US6573063B2 (en) | 1995-10-04 | 2003-06-03 | Cytoscan Sciences, Llc | Methods and systems for assessing biological materials using optical and spectroscopic detection techniques |
US5869243A (en) | 1996-03-05 | 1999-02-09 | Rhode Island Hospital | Immortalized hepatocytes |
US5817343A (en) | 1996-05-14 | 1998-10-06 | Alkermes, Inc. | Method for fabricating polymer-based controlled-release devices |
EP0915967A1 (en) | 1996-05-28 | 1999-05-19 | The Board Of Regents Of The University Of Michigan | Engineering oral tissues |
US6136212A (en) | 1996-08-12 | 2000-10-24 | The Regents Of The University Of Michigan | Polymer-based micromachining for microfluidic devices |
JP2002514128A (en) | 1997-01-16 | 2002-05-14 | イッスム リサーチ デベロップメント カンパニー オブ ザ ヒーブルー ユニバーシティ オブ エルサレム | Apparatus and method for performing biological modification of a body fluid |
US6287558B1 (en) | 1997-08-01 | 2001-09-11 | Biohybrio Technologies Llc | Devices containing cells or tissue and an agent that inhibits damage by a host cell molecule |
CA2227827A1 (en) | 1998-01-23 | 1999-07-23 | Unknown | In vitro artificial cornea and sclera |
US7191110B1 (en) | 1998-02-03 | 2007-03-13 | University Of Illinois, Board Of Trustees | Patient specific circulation model |
US6246466B1 (en) | 1998-02-25 | 2001-06-12 | Canon Kabushiki Kaisha | Sheet pack and recording apparatus |
DE69903800T2 (en) | 1998-03-18 | 2003-10-02 | Massachusetts Inst Technology | VASCULARIZED PERFUNDED ARRANGEMENTS FOR MICRO TISSUE AND MICROORGANES |
US6376169B1 (en) | 1998-05-01 | 2002-04-23 | Queens University At Kingston | Method for diagnosing a vascular condition |
US6542858B1 (en) | 1998-09-14 | 2003-04-01 | Lion Bioscience Ag | Pharmacokinetic-based drug design tool and method |
US6547994B1 (en) | 1998-11-13 | 2003-04-15 | Therics, Inc. | Rapid prototyping and manufacturing process |
US6165486A (en) | 1998-11-19 | 2000-12-26 | Carnegie Mellon University | Biocompatible compositions and methods of using same |
IT1304503B1 (en) | 1998-12-24 | 2001-03-19 | In Te C S R L | USE OF A SELECTIVE MEMBRANE IN A BIOMEDICAL DEVICE FOR THE EXTRA-BODY TREATMENT OF BLOOD AND OTHER ORGANIC LIQUIDS. |
WO2000047129A2 (en) | 1999-02-11 | 2000-08-17 | The General Hospital Corporation | Microfabricated membranes and matrices |
US20020090725A1 (en) | 2000-11-17 | 2002-07-11 | Simpson David G. | Electroprocessed collagen |
DE60017900T2 (en) | 1999-04-30 | 2006-04-06 | Massachusetts General Hospital, Boston | PREPARATION OF THREE-DIMENSIONAL VASCULARIZED TISSUE BY USING TWO-DIMENSIONAL MICRO-MADE SHAPES |
US7759113B2 (en) | 1999-04-30 | 2010-07-20 | The General Hospital Corporation | Fabrication of tissue lamina using microfabricated two-dimensional molds |
US20030129736A1 (en) | 1999-07-15 | 2003-07-10 | Eduardo Mitrani | Device and method for performing a biological modification of a fluid |
US6525242B1 (en) | 1999-11-02 | 2003-02-25 | The University Of Connecticut | Propagation of human hepatocytes in non-human mammals |
US6479064B1 (en) | 1999-12-29 | 2002-11-12 | Children's Medical Center Corporation | Culturing different cell populations on a decellularized natural biostructure for organ reconstruction |
DE10000823A1 (en) | 2000-01-12 | 2001-07-19 | Hartwin Hobler | Apparatus for introduction of a gas into a body fluid, a tissue fluid or a culture fluid comprises a channel with a gas outlet opening which is closed by means of gas-permeable barrier element |
US7241423B2 (en) | 2000-02-03 | 2007-07-10 | Cellular Process Chemistry, Inc. | Enhancing fluid flow in a stacked plate microreactor |
AU784377B2 (en) | 2000-03-14 | 2006-03-23 | Arthur V. Sampaio | Compositions and methods for affecting osteogenesis |
US7776021B2 (en) | 2000-04-28 | 2010-08-17 | The Charles Stark Draper Laboratory | Micromachined bilayer unit for filtration of small molecules |
US6458275B1 (en) | 2000-06-05 | 2002-10-01 | Harvard Apparatus, Inc. | Multi-well equilibrium dialysis system |
WO2002026939A2 (en) | 2000-09-25 | 2002-04-04 | The Board Of Trustees Of The University Of Illinois | Microfabrication of membranes for the growth of cells |
US6607910B1 (en) | 2000-11-13 | 2003-08-19 | Synthecon, Inc. | Two chamber cell culture vessel |
WO2002043792A1 (en) | 2000-11-28 | 2002-06-06 | Art Of Xen Limited | Gas exchange |
US7449180B2 (en) | 2001-02-06 | 2008-11-11 | John Kisiday | Macroscopic scaffold containing amphiphilic peptides encapsulating cells |
NL1017570C2 (en) | 2001-03-12 | 2002-09-13 | Stichting Hogeschool Van Utrec | Blood treatment device. |
US20030075498A1 (en) | 2001-06-01 | 2003-04-24 | Watkins Randolph H. | Hemodialyzer headers |
WO2003050297A1 (en) | 2001-10-31 | 2003-06-19 | Bristol-Myers Squibb Company | Methods of screening for toxicity of test compounds |
US7597677B2 (en) | 2001-11-16 | 2009-10-06 | National Quality Care, Inc. | Wearable ultrafiltration device |
BR0214217A (en) | 2001-11-16 | 2004-09-21 | Childrens Medical Center | Increased Organ Function |
US20030121594A1 (en) | 2001-12-28 | 2003-07-03 | Brill Russell P. | Method for manufacture of tubular multilayer structure from fiber-resin material |
DE10203237B4 (en) | 2002-01-28 | 2006-08-17 | Siemens Ag | Method for magnetic resonance imaging with automatic adjustment of the measuring field |
AU2003214155A1 (en) | 2002-03-12 | 2003-09-29 | The Regents Of The University Of California | Vascularized tissue for transplantation |
WO2003104439A2 (en) | 2002-03-12 | 2003-12-18 | Surface Logix, Inc. | Assay device that analyzes the absorption, metabolism, permeability and/or toxicity of a candidate compound |
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US8147562B2 (en) | 2002-09-23 | 2012-04-03 | The General Hospital Corporation | Three dimensional construct for the design and fabrication of physiological fluidic networks |
US20040147016A1 (en) | 2002-09-30 | 2004-07-29 | Rowley Jonathan A. | Programmable scaffold and methods for making and using the same |
US7264723B2 (en) | 2002-11-01 | 2007-09-04 | Sandia Corporation | Dialysis on microchips using thin porous polymer membranes |
EP1636351A4 (en) | 2003-05-21 | 2007-04-04 | Gen Hospital Corp | Microfabricated compositions and processes for engineering tissues containing multiple cell types |
WO2005003317A2 (en) | 2003-07-01 | 2005-01-13 | Regents Of The University Of Minnesota | Engineered blood vessels |
CA2583360C (en) | 2004-10-06 | 2016-01-26 | State Of Oregon Acting By And Through The State Board Of Higher Education On Behalf Of Oregon State University | Microtechnology-based dialyzer |
US7955504B1 (en) | 2004-10-06 | 2011-06-07 | State Of Oregon Acting By And Through The State Board Of Higher Education On Behalf Of Oregon State University | Microfluidic devices, particularly filtration devices comprising polymeric membranes, and method for their manufacture and use |
US20070125489A1 (en) | 2005-09-08 | 2007-06-07 | Oregon State University | Microfluidic welded devices or components thereof and method for their manufacture |
US8647861B2 (en) | 2008-07-16 | 2014-02-11 | Children's Medical Center Corporation | Organ mimic device with microchannels and methods of use and manufacturing thereof |
JP2012531256A (en) | 2009-06-24 | 2012-12-10 | ステイト オブ オレゴン アクティング バイ アンド スルー ザ ステイト ボード オブ ハイヤー エデュケーション オン ビハーフ オブ オレゴン ステイト ユニバーシティー | Microfluidic device for dialysis |
US8801922B2 (en) | 2009-06-24 | 2014-08-12 | State Of Oregon Acting By And Through The State Board Of Higher Education On Behalf Of Oregon State University | Dialysis system |
-
2004
- 2004-05-21 EP EP04809403A patent/EP1636351A4/en not_active Withdrawn
- 2004-05-21 WO PCT/US2004/016059 patent/WO2005034624A2/en active Application Filing
- 2004-05-21 US US10/557,081 patent/US7960166B2/en active Active
-
2011
- 2011-06-09 US US13/156,675 patent/US8357528B2/en active Active
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5518680A (en) * | 1993-10-18 | 1996-05-21 | Massachusetts Institute Of Technology | Tissue regeneration matrices by solid free form fabrication techniques |
US6139574A (en) * | 1993-10-18 | 2000-10-31 | Children's Medical Center Corporation | Vascularized tissue regeneration matrices formed by solid free form fabrication techniques |
US5665596A (en) * | 1995-07-31 | 1997-09-09 | Becton, Dickinson And Company | Device for cell co-culture and method for its use in culturing cells |
US6143293A (en) * | 1998-03-26 | 2000-11-07 | Carnegie Mellon | Assembled scaffolds for three dimensional cell culturing and tissue generation |
US20020182241A1 (en) * | 2001-01-02 | 2002-12-05 | Borenstein Jeffrey T. | Tissue engineering of three-dimensional vascularized using microfabricated polymer assembly technology |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9498501B2 (en) | 2003-06-27 | 2016-11-22 | DePuy Synthes Products, Inc. | Postpartum cells derived from umbilical cord tissue, and methods of making and using the same |
US9579351B2 (en) | 2003-06-27 | 2017-02-28 | DePuy Synthes Products, Inc. | Postpartum cells derived from placental tissue, and methods of making and using the same |
US9314420B2 (en) | 2005-10-26 | 2016-04-19 | Jan-Eric Ahlfors | Acellular bioabsorbable tissue regeneration matrices |
Also Published As
Publication number | Publication date |
---|---|
EP1636351A4 (en) | 2007-04-04 |
US20110256619A1 (en) | 2011-10-20 |
US7960166B2 (en) | 2011-06-14 |
WO2005034624A2 (en) | 2005-04-21 |
EP1636351A2 (en) | 2006-03-22 |
US8357528B2 (en) | 2013-01-22 |
US20070281353A1 (en) | 2007-12-06 |
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