WO2005037173A3 - System and method for mapping diaphragm electrode sites - Google Patents

System and method for mapping diaphragm electrode sites Download PDF

Info

Publication number
WO2005037173A3
WO2005037173A3 PCT/US2004/034212 US2004034212W WO2005037173A3 WO 2005037173 A3 WO2005037173 A3 WO 2005037173A3 US 2004034212 W US2004034212 W US 2004034212W WO 2005037173 A3 WO2005037173 A3 WO 2005037173A3
Authority
WO
WIPO (PCT)
Prior art keywords
diaphragm
electrodes
electrode sites
stimulus
mapping
Prior art date
Application number
PCT/US2004/034212
Other languages
French (fr)
Other versions
WO2005037173A2 (en
Inventor
Amir J Tehrani
Chang Lee
David Ligon
Anthony Mo
Mark Meltzer
Original Assignee
Inspiration Medical Inc
Amir J Tehrani
Chang Lee
David Ligon
Anthony Mo
Mark Meltzer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Inspiration Medical Inc, Amir J Tehrani, Chang Lee, David Ligon, Anthony Mo, Mark Meltzer filed Critical Inspiration Medical Inc
Publication of WO2005037173A2 publication Critical patent/WO2005037173A2/en
Publication of WO2005037173A3 publication Critical patent/WO2005037173A3/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/36128Control systems
    • A61N1/36132Control systems using patient feedback
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3601Applying electric currents by contact electrodes alternating or intermittent currents for stimulation of respiratory organs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/24Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/316Modalities, i.e. specific diagnostic methods
    • A61B5/389Electromyography [EMG]
    • A61B5/395Details of stimulation, e.g. nerve stimulation to elicit EMG response
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/08Detecting, measuring or recording devices for evaluating the respiratory organs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/24Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/316Modalities, i.e. specific diagnostic methods
    • A61B5/389Electromyography [EMG]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/48Other medical applications
    • A61B5/4806Sleep evaluation
    • A61B5/4818Sleep apnoea
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/72Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7235Details of waveform analysis
    • A61B5/7264Classification of physiological signals or data, e.g. using neural networks, statistical classifiers, expert systems or fuzzy systems

Abstract

A signal source coupled to one or more electrodes in the vicinity of the diaphragm for mapping therapeutic electrode sites. A stimulus signal from the signal source may be applied to the one or more electrodes to produce activation of the diaphragm. Activation of the diaphragm is sensed to provide information that may be correlated with the stimulus signal. The correlated information may be used to identify a therapeutic locus for a therapeutic electrode. An electrical stimulus comprising a series of pulses may be applied to the one or more electrodes to elicit a desired breathing response. The electrical stimulus may be applied between intrinsic breathing cycles, or between regulated breathing cycles. More than one electrode may be supported on a single substrate. The substrate may configured to be positioned on the diaphragm. A hierarchy of stimuli may be applied to a set of electrodes.
PCT/US2004/034212 2003-10-15 2004-10-15 System and method for mapping diaphragm electrode sites WO2005037173A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/686,891 2003-10-15
US10/686,891 US8467876B2 (en) 2003-10-15 2003-10-15 Breathing disorder detection and therapy delivery device and method

Publications (2)

Publication Number Publication Date
WO2005037173A2 WO2005037173A2 (en) 2005-04-28
WO2005037173A3 true WO2005037173A3 (en) 2005-06-30

Family

ID=34465515

Family Applications (6)

Application Number Title Priority Date Filing Date
PCT/US2004/034212 WO2005037173A2 (en) 2003-10-15 2004-10-15 System and method for mapping diaphragm electrode sites
PCT/US2004/034170 WO2005037220A2 (en) 2003-10-15 2004-10-15 Breathing disorder detection and therapy delivery device and method
PCT/US2004/034213 WO2005037174A2 (en) 2003-10-15 2004-10-15 System and method for diaphragm stimulation
PCT/US2004/034211 WO2005037077A2 (en) 2003-10-15 2004-10-15 Heart failure patient treatment and management device
PCT/US2004/033850 WO2005037172A2 (en) 2003-10-15 2004-10-15 Breathing therapy device and method
PCT/US2004/034103 WO2005037366A1 (en) 2003-10-15 2004-10-15 Device and method with a precursor predictor for treating a breathing disorder

Family Applications After (5)

Application Number Title Priority Date Filing Date
PCT/US2004/034170 WO2005037220A2 (en) 2003-10-15 2004-10-15 Breathing disorder detection and therapy delivery device and method
PCT/US2004/034213 WO2005037174A2 (en) 2003-10-15 2004-10-15 System and method for diaphragm stimulation
PCT/US2004/034211 WO2005037077A2 (en) 2003-10-15 2004-10-15 Heart failure patient treatment and management device
PCT/US2004/033850 WO2005037172A2 (en) 2003-10-15 2004-10-15 Breathing therapy device and method
PCT/US2004/034103 WO2005037366A1 (en) 2003-10-15 2004-10-15 Device and method with a precursor predictor for treating a breathing disorder

Country Status (3)

Country Link
US (15) US8467876B2 (en)
DE (3) DE112004001957T5 (en)
WO (6) WO2005037173A2 (en)

Families Citing this family (306)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8932227B2 (en) 2000-07-28 2015-01-13 Lawrence A. Lynn System and method for CO2 and oximetry integration
US9468378B2 (en) 1997-01-27 2016-10-18 Lawrence A. Lynn Airway instability detection system and method
US9042952B2 (en) 1997-01-27 2015-05-26 Lawrence A. Lynn System and method for automatic detection of a plurality of SPO2 time series pattern types
US6024089A (en) 1997-03-14 2000-02-15 Nelcor Puritan Bennett Incorporated System and method for setting and displaying ventilator alarms
US9521971B2 (en) 1997-07-14 2016-12-20 Lawrence A. Lynn System and method for automatic detection of a plurality of SPO2 time series pattern types
US20060195041A1 (en) 2002-05-17 2006-08-31 Lynn Lawrence A Centralized hospital monitoring system for automatically detecting upper airway instability and for preventing and aborting adverse drug reactions
US9053222B2 (en) 2002-05-17 2015-06-09 Lawrence A. Lynn Patient safety processor
US7206635B2 (en) * 2001-06-07 2007-04-17 Medtronic, Inc. Method and apparatus for modifying delivery of a therapy in response to onset of sleep
US20080077192A1 (en) * 2002-05-03 2008-03-27 Afferent Corporation System and method for neuro-stimulation
DE10248590B4 (en) 2002-10-17 2016-10-27 Resmed R&D Germany Gmbh Method and device for carrying out a signal-processing observation of a measurement signal associated with the respiratory activity of a person
US7477932B2 (en) * 2003-05-28 2009-01-13 Cardiac Pacemakers, Inc. Cardiac waveform template creation, maintenance and use
WO2005009291A2 (en) * 2003-07-23 2005-02-03 Synapse Biomedical, Inc. System and method for conditioning a diaphragm of a patient
US7575553B2 (en) * 2003-09-18 2009-08-18 Cardiac Pacemakers, Inc. Methods and systems for assessing pulmonary disease
US7887493B2 (en) 2003-09-18 2011-02-15 Cardiac Pacemakers, Inc. Implantable device employing movement sensing for detecting sleep-related disorders
US7510531B2 (en) * 2003-09-18 2009-03-31 Cardiac Pacemakers, Inc. System and method for discrimination of central and obstructive disordered breathing events
US7662101B2 (en) * 2003-09-18 2010-02-16 Cardiac Pacemakers, Inc. Therapy control based on cardiopulmonary status
US20050107838A1 (en) * 2003-09-18 2005-05-19 Lovett Eric G. Subcutaneous cardiac rhythm management with disordered breathing detection and treatment
US7396333B2 (en) 2003-08-18 2008-07-08 Cardiac Pacemakers, Inc. Prediction of disordered breathing
EP1670547B1 (en) 2003-08-18 2008-11-12 Cardiac Pacemakers, Inc. Patient monitoring system
US8002553B2 (en) 2003-08-18 2011-08-23 Cardiac Pacemakers, Inc. Sleep quality data collection and evaluation
US8265759B2 (en) * 2003-10-15 2012-09-11 Rmx, Llc Device and method for treating disorders of the cardiovascular system or heart
US8140164B2 (en) * 2003-10-15 2012-03-20 Rmx, Llc Therapeutic diaphragm stimulation device and method
US8244358B2 (en) 2003-10-15 2012-08-14 Rmx, Llc Device and method for treating obstructive sleep apnea
US7970475B2 (en) 2003-10-15 2011-06-28 Rmx, Llc Device and method for biasing lung volume
US8160711B2 (en) 2003-10-15 2012-04-17 Rmx, Llc Multimode device and method for controlling breathing
US7979128B2 (en) * 2003-10-15 2011-07-12 Rmx, Llc Device and method for gradually controlling breathing
US20080161878A1 (en) * 2003-10-15 2008-07-03 Tehrani Amir J Device and method to for independently stimulating hemidiaphragms
US20060167523A1 (en) * 2003-10-15 2006-07-27 Tehrani Amir J Device and method for improving upper airway functionality
US9259573B2 (en) * 2003-10-15 2016-02-16 Rmx, Llc Device and method for manipulating exhalation
US8467876B2 (en) * 2003-10-15 2013-06-18 Rmx, Llc Breathing disorder detection and therapy delivery device and method
US20050085874A1 (en) * 2003-10-17 2005-04-21 Ross Davis Method and system for treating sleep apnea
US7319900B2 (en) * 2003-12-11 2008-01-15 Cardiac Pacemakers, Inc. Cardiac response classification using multiple classification windows
US20060247693A1 (en) 2005-04-28 2006-11-02 Yanting Dong Non-captured intrinsic discrimination in cardiac pacing response classification
US7774064B2 (en) 2003-12-12 2010-08-10 Cardiac Pacemakers, Inc. Cardiac response classification using retriggerable classification windows
US8521284B2 (en) 2003-12-12 2013-08-27 Cardiac Pacemakers, Inc. Cardiac response classification using multisite sensing and pacing
US7363085B1 (en) * 2004-01-26 2008-04-22 Pacesetters, Inc. Augmenting hypoventilation
US7421296B1 (en) * 2004-01-26 2008-09-02 Pacesetter, Inc. Termination of respiratory oscillations characteristic of Cheyne-Stokes respiration
US7314451B2 (en) 2005-04-25 2008-01-01 Earlysense Ltd. Techniques for prediction and monitoring of clinical episodes
US8942779B2 (en) 2004-02-05 2015-01-27 Early Sense Ltd. Monitoring a condition of a subject
US8403865B2 (en) 2004-02-05 2013-03-26 Earlysense Ltd. Prediction and monitoring of clinical episodes
US20070118054A1 (en) * 2005-11-01 2007-05-24 Earlysense Ltd. Methods and systems for monitoring patients for clinical episodes
US8491492B2 (en) 2004-02-05 2013-07-23 Earlysense Ltd. Monitoring a condition of a subject
JP4809779B2 (en) 2004-02-05 2011-11-09 アーリーセンス・リミテッド Prediction and monitoring technology for clinical onset in respiration
US20050197588A1 (en) * 2004-03-04 2005-09-08 Scott Freeberg Sleep disordered breathing alert system
US7751894B1 (en) * 2004-03-04 2010-07-06 Cardiac Pacemakers, Inc. Systems and methods for indicating aberrant behavior detected by an implanted medical device
US7371220B1 (en) * 2004-06-30 2008-05-13 Pacesetter, Inc. System and method for real-time apnea/hypopnea detection using an implantable medical system
US7269458B2 (en) * 2004-08-09 2007-09-11 Cardiac Pacemakers, Inc. Cardiopulmonary functional status assessment via heart rate response detection by implantable cardiac device
US7389143B2 (en) 2004-08-12 2008-06-17 Cardiac Pacemakers, Inc. Cardiopulmonary functional status assessment via metabolic response detection by implantable cardiac device
JP2006136511A (en) * 2004-11-12 2006-06-01 Matsushita Electric Ind Co Ltd Drum type washing/drying machine
ES2476395T3 (en) * 2004-11-22 2014-07-14 Techno Link Co., Ltd. Stimulation apparatus, for the prevention of apnea
US8473058B2 (en) * 2004-11-22 2013-06-25 Mitsuru Sasaki Apnea preventing stimulation apparatus
US20060122661A1 (en) * 2004-12-03 2006-06-08 Mandell Lee J Diaphragmatic pacing with activity monitor adjustment
US7966072B2 (en) * 2005-02-18 2011-06-21 Palo Alto Investors Methods and compositions for treating obesity-hypoventilation syndrome
US7680534B2 (en) 2005-02-28 2010-03-16 Cardiac Pacemakers, Inc. Implantable cardiac device with dyspnea measurement
US7704211B1 (en) * 2005-03-21 2010-04-27 Pacesetter, Inc. Method and apparatus for assessing fluid level in lungs
US7404799B1 (en) * 2005-04-05 2008-07-29 Pacesetter, Inc. System and method for detection of respiration patterns via integration of intracardiac electrogram signals
US7630763B2 (en) 2005-04-20 2009-12-08 Cardiac Pacemakers, Inc. Thoracic or intracardiac impedance detection with automatic vector selection
US7392086B2 (en) 2005-04-26 2008-06-24 Cardiac Pacemakers, Inc. Implantable cardiac device and method for reduced phrenic nerve stimulation
US7499751B2 (en) * 2005-04-28 2009-03-03 Cardiac Pacemakers, Inc. Cardiac signal template generation using waveform clustering
US8900154B2 (en) * 2005-05-24 2014-12-02 Cardiac Pacemakers, Inc. Prediction of thoracic fluid accumulation
US20060271121A1 (en) 2005-05-25 2006-11-30 Cardiac Pacemakers, Inc. Closed loop impedance-based cardiac resynchronization therapy systems, devices, and methods
US7644714B2 (en) 2005-05-27 2010-01-12 Apnex Medical, Inc. Devices and methods for treating sleep disorders
US8364455B2 (en) * 2005-06-09 2013-01-29 Maquet Critical Care Ab Simulator for use with a breathing-assist device
US8036750B2 (en) * 2005-06-13 2011-10-11 Cardiac Pacemakers, Inc. System for neural control of respiration
US20070021678A1 (en) * 2005-07-19 2007-01-25 Cardiac Pacemakers, Inc. Methods and apparatus for monitoring physiological responses to steady state activity
US9839781B2 (en) 2005-08-22 2017-12-12 Cardiac Pacemakers, Inc. Intracardiac impedance and its applications
US8494618B2 (en) * 2005-08-22 2013-07-23 Cardiac Pacemakers, Inc. Intracardiac impedance and its applications
US20070044669A1 (en) * 2005-08-24 2007-03-01 Geise Gregory D Aluminum can compacting mechanism with improved actuation handle assembly
US9050005B2 (en) * 2005-08-25 2015-06-09 Synapse Biomedical, Inc. Method and apparatus for transgastric neurostimulation
US7731663B2 (en) 2005-09-16 2010-06-08 Cardiac Pacemakers, Inc. System and method for generating a trend parameter based on respiration rate distribution
US7974691B2 (en) * 2005-09-21 2011-07-05 Cardiac Pacemakers, Inc. Method and apparatus for controlling cardiac resynchronization therapy using cardiac impedance
EP2124061A3 (en) * 2005-11-04 2010-03-24 ResMed Limited Methods and apparatuses to aid the diagnosis and management of sleep disordered breathing
CA2865410C (en) 2005-11-18 2022-04-26 Mark Gelfand System and method to modulate phrenic nerve to prevent sleep apnea
US10406366B2 (en) 2006-11-17 2019-09-10 Respicardia, Inc. Transvenous phrenic nerve stimulation system
EP2335775B1 (en) * 2005-12-01 2018-02-07 Second Sight Medical Products, Inc. Fitting a neural prosthesis using impedance and electrode height
US7766840B2 (en) * 2005-12-01 2010-08-03 Cardiac Pacemakers, Inc. Method and system for heart failure status evaluation based on a disordered breathing index
CN101495177A (en) * 2005-12-02 2009-07-29 突触生物医学有限公司 Transvisceral neurostimulation mapping device and method
US8281792B2 (en) * 2005-12-31 2012-10-09 John W Royalty Electromagnetic diaphragm assist device and method for assisting a diaphragm function
US8676323B2 (en) * 2006-03-09 2014-03-18 Synapse Biomedical, Inc. Ventilatory assist system and methods to improve respiratory function
US8615309B2 (en) * 2006-03-29 2013-12-24 Catholic Healthcare West Microburst electrical stimulation of cranial nerves for the treatment of medical conditions
US8021310B2 (en) 2006-04-21 2011-09-20 Nellcor Puritan Bennett Llc Work of breathing display for a ventilation system
JP2009538176A (en) * 2006-05-23 2009-11-05 パブリークレヒテリケ レヒトスペルスーン アカデミッシュ ジーケンハウス ライデン エイチ.オウ.ディー.エヌ. レイズ ユニベルシテール メディシュ シーイー Medical probe
KR100845464B1 (en) * 2006-06-14 2008-07-10 (주)머티리얼솔루션테크놀로지 Implantable diaphragm stimulator and breathing pacemaker using the same
US8226570B2 (en) * 2006-08-08 2012-07-24 Cardiac Pacemakers, Inc. Respiration monitoring for heart failure using implantable device
US20080071185A1 (en) * 2006-08-08 2008-03-20 Cardiac Pacemakers, Inc. Periodic breathing during activity
US8103341B2 (en) * 2006-08-25 2012-01-24 Cardiac Pacemakers, Inc. System for abating neural stimulation side effects
US8121692B2 (en) * 2006-08-30 2012-02-21 Cardiac Pacemakers, Inc. Method and apparatus for neural stimulation with respiratory feedback
US8050765B2 (en) * 2006-08-30 2011-11-01 Cardiac Pacemakers, Inc. Method and apparatus for controlling neural stimulation during disordered breathing
JP5236647B2 (en) * 2006-09-11 2013-07-17 コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ System and method for electrode placement on patient body
US8209013B2 (en) 2006-09-14 2012-06-26 Cardiac Pacemakers, Inc. Therapeutic electrical stimulation that avoids undesirable activation
US7784461B2 (en) 2006-09-26 2010-08-31 Nellcor Puritan Bennett Llc Three-dimensional waveform display for a breathing assistance system
US20080072902A1 (en) * 2006-09-27 2008-03-27 Nellcor Puritan Bennett Incorporated Preset breath delivery therapies for a breathing assistance system
US9186511B2 (en) 2006-10-13 2015-11-17 Cyberonics, Inc. Obstructive sleep apnea treatment devices, systems and methods
US9913982B2 (en) 2011-01-28 2018-03-13 Cyberonics, Inc. Obstructive sleep apnea treatment devices, systems and methods
US9205262B2 (en) 2011-05-12 2015-12-08 Cyberonics, Inc. Devices and methods for sleep apnea treatment
US8417343B2 (en) 2006-10-13 2013-04-09 Apnex Medical, Inc. Obstructive sleep apnea treatment devices, systems and methods
US9744354B2 (en) 2008-12-31 2017-08-29 Cyberonics, Inc. Obstructive sleep apnea treatment devices, systems and methods
US8855771B2 (en) 2011-01-28 2014-10-07 Cyberonics, Inc. Screening devices and methods for obstructive sleep apnea therapy
US20080109047A1 (en) * 2006-10-26 2008-05-08 Pless Benjamin D Apnea treatment device
US7917194B1 (en) * 2006-11-15 2011-03-29 Pacesetter, Inc. Method and apparatus for detecting pulmonary edema
US8280513B2 (en) * 2006-12-22 2012-10-02 Rmx, Llc Device and method to treat flow limitations
US9968266B2 (en) 2006-12-27 2018-05-15 Cardiac Pacemakers, Inc. Risk stratification based heart failure detection algorithm
US8909341B2 (en) * 2007-01-22 2014-12-09 Respicardia, Inc. Device and method for the treatment of breathing disorders and cardiac disorders
WO2008092246A1 (en) 2007-01-29 2008-08-07 Simon Fraser University Transvascular nerve stimulation apparatus and methods
WO2008095108A1 (en) * 2007-02-01 2008-08-07 Ls Biopath, Inc. Electrical systems for detection and characterization of abnormal tissue and cells
US9566030B2 (en) * 2007-02-01 2017-02-14 Ls Biopath, Inc. Optical system for detection and characterization of abnormal tissue and cells
WO2008098001A2 (en) * 2007-02-05 2008-08-14 Synapse Biomedical, Inc. Removable intramuscular electrode
US8417351B2 (en) * 2007-02-09 2013-04-09 Mayo Foundation For Medical Education And Research Peripheral oxistimulator apparatus and methods
US20080228093A1 (en) * 2007-03-13 2008-09-18 Yanting Dong Systems and methods for enhancing cardiac signal features used in morphology discrimination
US20080234556A1 (en) * 2007-03-20 2008-09-25 Cardiac Pacemakers, Inc. Method and apparatus for sensing respiratory activities using sensor in lymphatic system
US20080243016A1 (en) * 2007-03-28 2008-10-02 Cardiac Pacemakers, Inc. Pulmonary Artery Pressure Signals And Methods of Using
US7950560B2 (en) * 2007-04-13 2011-05-31 Tyco Healthcare Group Lp Powered surgical instrument
US11259801B2 (en) * 2007-04-13 2022-03-01 Covidien Lp Powered surgical instrument
WO2009138976A2 (en) 2008-05-12 2009-11-19 Earlysense Ltd Monitoring, predicting and treating clinical episodes
US8585607B2 (en) 2007-05-02 2013-11-19 Earlysense Ltd. Monitoring, predicting and treating clinical episodes
WO2008144578A1 (en) * 2007-05-17 2008-11-27 Synapse Biomedical, Inc. Devices and methods for assessing motor point electromyogram as a biomarker
EP2152362B1 (en) * 2007-05-28 2015-07-08 St. Jude Medical AB Implantable medical device for monitoring lung deficiency
US8983609B2 (en) 2007-05-30 2015-03-17 The Cleveland Clinic Foundation Apparatus and method for treating pulmonary conditions
US9987488B1 (en) 2007-06-27 2018-06-05 Respicardia, Inc. Detecting and treating disordered breathing
US20090024176A1 (en) * 2007-07-17 2009-01-22 Joonkyoo Anthony Yun Methods and devices for producing respiratory sinus arrhythmia
US20090024047A1 (en) * 2007-07-20 2009-01-22 Cardiac Pacemakers, Inc. Devices and methods for respiration therapy
US8265736B2 (en) 2007-08-07 2012-09-11 Cardiac Pacemakers, Inc. Method and apparatus to perform electrode combination selection
US9037239B2 (en) 2007-08-07 2015-05-19 Cardiac Pacemakers, Inc. Method and apparatus to perform electrode combination selection
CN102727975B (en) * 2007-08-22 2016-03-30 纽约州立大学研究基金会 Breathing gas supply and shared system and method thereof
US8135471B2 (en) 2007-08-28 2012-03-13 Cardiac Pacemakers, Inc. Method and apparatus for inspiratory muscle stimulation using implantable device
US8460189B2 (en) 2007-09-14 2013-06-11 Corventis, Inc. Adherent cardiac monitor with advanced sensing capabilities
US8591430B2 (en) 2007-09-14 2013-11-26 Corventis, Inc. Adherent device for respiratory monitoring
US20090076345A1 (en) 2007-09-14 2009-03-19 Corventis, Inc. Adherent Device with Multiple Physiological Sensors
US9186089B2 (en) 2007-09-14 2015-11-17 Medtronic Monitoring, Inc. Injectable physiological monitoring system
WO2009036348A1 (en) 2007-09-14 2009-03-19 Corventis, Inc. Medical device automatic start-up upon contact to patient tissue
US8790257B2 (en) * 2007-09-14 2014-07-29 Corventis, Inc. Multi-sensor patient monitor to detect impending cardiac decompensation
US20090076343A1 (en) 2007-09-14 2009-03-19 Corventis, Inc. Energy Management for Adherent Patient Monitor
WO2009048610A1 (en) 2007-10-10 2009-04-16 Cardiac Pacemakers, Inc. Respiratory stimulation for treating periodic breathing
JP5425793B2 (en) 2007-10-12 2014-02-26 ペイシェンツライクミー, インコーポレイテッド Personal management and comparison of medical conditions and outcomes based on patient community profiles
WO2009059033A1 (en) * 2007-10-30 2009-05-07 Synapse Biomedical, Inc. Method of improving sleep disordered breathing
US8428726B2 (en) 2007-10-30 2013-04-23 Synapse Biomedical, Inc. Device and method of neuromodulation to effect a functionally restorative adaption of the neuromuscular system
US20170188940A9 (en) 2007-11-26 2017-07-06 Whispersom Corporation Device to detect and treat Apneas and Hypopnea
US8155744B2 (en) 2007-12-13 2012-04-10 The Cleveland Clinic Foundation Neuromodulatory methods for treating pulmonary disorders
WO2009091583A1 (en) * 2008-01-16 2009-07-23 Massachusetts Institute Of Technology Method and apparatus for predicting patient outcomes form a physiological segmentable patient signal
US9199075B1 (en) 2008-02-07 2015-12-01 Respicardia, Inc. Transvascular medical lead
CN101939051B (en) 2008-02-14 2013-07-10 心脏起搏器公司 Method and apparatus for phrenic stimulation detection
EP2257216B1 (en) 2008-03-12 2021-04-28 Medtronic Monitoring, Inc. Heart failure decompensation prediction based on cardiac rhythm
US20110054279A1 (en) * 2008-03-27 2011-03-03 Widemed Ltd. Diagnosis of periodic breathing
US8412317B2 (en) 2008-04-18 2013-04-02 Corventis, Inc. Method and apparatus to measure bioelectric impedance of patient tissue
US8882684B2 (en) 2008-05-12 2014-11-11 Earlysense Ltd. Monitoring, predicting and treating clinical episodes
US9883809B2 (en) 2008-05-01 2018-02-06 Earlysense Ltd. Monitoring, predicting and treating clinical episodes
WO2009137682A1 (en) 2008-05-07 2009-11-12 Lynn Lawrence A Medical failure pattern search engine
EP3181191B1 (en) * 2008-05-15 2020-03-11 Inspire Medical Systems, Inc. Apparatus for sensing respiratory pressure in an implantable stimulation system
US8229566B2 (en) * 2008-06-25 2012-07-24 Sheng Li Method and apparatus of breathing-controlled electrical stimulation for skeletal muscles
US20100016743A1 (en) * 2008-07-17 2010-01-21 Syed Zeeshan H Identifying Groups of Patients with Similar Physiological Characteristics and Risk Profiles
US8372013B2 (en) 2008-09-19 2013-02-12 Medtronic, Inc. Method and apparatus for determining a respiration parameter in a medical device
US8302602B2 (en) 2008-09-30 2012-11-06 Nellcor Puritan Bennett Llc Breathing assistance system with multiple pressure sensors
EP3714771A1 (en) 2008-10-01 2020-09-30 Inspire Medical Systems, Inc. System for treating sleep apnea transvenously
US20100087893A1 (en) * 2008-10-03 2010-04-08 Solange Pasquet Operant Conditioning-Based Device for Snoring and Obstructive Sleep Apnea and Method of Use
US8644939B2 (en) * 2008-11-18 2014-02-04 Neurostream Technologies General Partnership Method and device for the detection, identification and treatment of sleep apnea/hypopnea
EP3184045B1 (en) 2008-11-19 2023-12-06 Inspire Medical Systems, Inc. System treating sleep disordered breathing
EP2375968B1 (en) 2008-12-15 2018-11-14 Medtronic Monitoring, Inc. Patient monitoring systems and methods
EP2198779B1 (en) * 2008-12-22 2018-09-19 Sendsor GmbH Device and method for early detection of exacerbations
US8870773B2 (en) * 2009-02-09 2014-10-28 The Cleveland Clinic Foundation Ultrasound-guided delivery of a therapy delivery device to a nerve target
US20100204567A1 (en) * 2009-02-09 2010-08-12 The Cleveland Clinic Foundation Ultrasound-guided delivery of a therapy delivery device to a phrenic nerve
WO2010117810A1 (en) 2009-03-31 2010-10-14 Inspire Medical Systems, Inc. Percutaneous access for systems of treating sleep-related disordered breathing
JP5501445B2 (en) 2009-04-30 2014-05-21 ペイシェンツライクミー, インコーポレイテッド System and method for facilitating data submission within an online community
US8378832B2 (en) * 2009-07-09 2013-02-19 Harry J. Cassidy Breathing disorder treatment system and method
US8285373B2 (en) 2009-07-15 2012-10-09 Cardiac Pacemakers, Inc. Remote sensing in an implantable medical device
US8301241B2 (en) 2009-07-15 2012-10-30 Cardiac Pacemakers, Inc. Remote pace detection in an implantable medical device
EP2453977B1 (en) 2009-07-15 2017-11-08 Cardiac Pacemakers, Inc. Physiological vibration detection in an implanted medical device
US20120165623A1 (en) * 2009-08-28 2012-06-28 Lawrence Allan Lynn Relational Thermorespirometer Spot Vitals Monitor
US9072899B1 (en) * 2009-09-04 2015-07-07 Todd Nickloes Diaphragm pacemaker
US8233987B2 (en) 2009-09-10 2012-07-31 Respicardia, Inc. Respiratory rectification
BR112012005719A2 (en) * 2009-09-14 2020-07-21 Sleep Methods system and method for training and promoting a conditioned stimulus intervention during sleep.
WO2011050283A2 (en) 2009-10-22 2011-04-28 Corventis, Inc. Remote detection and monitoring of functional chronotropic incompetence
US8409108B2 (en) * 2009-11-05 2013-04-02 Inovise Medical, Inc. Multi-axial heart sounds and murmur detection for hemodynamic-condition assessment
US8335992B2 (en) 2009-12-04 2012-12-18 Nellcor Puritan Bennett Llc Visual indication of settings changes on a ventilator graphical user interface
USD638852S1 (en) 2009-12-04 2011-05-31 Nellcor Puritan Bennett Llc Ventilator display screen with an alarm icon
USD649157S1 (en) 2009-12-04 2011-11-22 Nellcor Puritan Bennett Llc Ventilator display screen with a user interface
US8924878B2 (en) 2009-12-04 2014-12-30 Covidien Lp Display and access to settings on a ventilator graphical user interface
US9119925B2 (en) 2009-12-04 2015-09-01 Covidien Lp Quick initiation of respiratory support via a ventilator user interface
US9451897B2 (en) 2009-12-14 2016-09-27 Medtronic Monitoring, Inc. Body adherent patch with electronics for physiologic monitoring
US9262588B2 (en) 2009-12-18 2016-02-16 Covidien Lp Display of respiratory data graphs on a ventilator graphical user interface
US8499252B2 (en) 2009-12-18 2013-07-30 Covidien Lp Display of respiratory data graphs on a ventilator graphical user interface
JP2011213096A (en) * 2010-03-19 2011-10-27 Makita Corp Power tool
US8965498B2 (en) 2010-04-05 2015-02-24 Corventis, Inc. Method and apparatus for personalized physiologic parameters
US11723542B2 (en) * 2010-08-13 2023-08-15 Respiratory Motion, Inc. Advanced respiratory monitor and system
US8983572B2 (en) 2010-10-29 2015-03-17 Inspire Medical Systems, Inc. System and method for patient selection in treating sleep disordered breathing
US8585604B2 (en) 2010-10-29 2013-11-19 Medtronic, Inc. Integrated patient care
KR20120046554A (en) * 2010-11-02 2012-05-10 연세대학교 산학협력단 Sensor for detecting cancer tissue and manufacturing method of the same
US9457186B2 (en) 2010-11-15 2016-10-04 Bluewind Medical Ltd. Bilateral feedback
US9186504B2 (en) 2010-11-15 2015-11-17 Rainbow Medical Ltd Sleep apnea treatment
WO2012069957A1 (en) * 2010-11-23 2012-05-31 Koninklijke Philips Electronics N.V. Obesity hypoventilation syndrome treatment system and method
US10292625B2 (en) 2010-12-07 2019-05-21 Earlysense Ltd. Monitoring a sleeping subject
US20120157799A1 (en) * 2010-12-20 2012-06-21 Abhilash Patangay Using device based sensors to classify events and generate alerts
US8827930B2 (en) * 2011-01-10 2014-09-09 Bioguidance Llc System and method for patient monitoring
US9744349B2 (en) 2011-02-10 2017-08-29 Respicardia, Inc. Medical lead and implantation
AU2012231762B2 (en) * 2011-03-23 2015-06-18 Resmed Limited Detection of ventilation sufficiency
EP2713870A4 (en) * 2011-06-03 2014-10-22 Los Angeles Childrens Hospital Electrophysiological diagnosis and treatment for asthma
US8478413B2 (en) 2011-07-27 2013-07-02 Medtronic, Inc. Bilateral phrenic nerve stimulation with reduced dyssynchrony
US8706235B2 (en) 2011-07-27 2014-04-22 Medtronic, Inc. Transvenous method to induce respiration
US9861817B2 (en) 2011-07-28 2018-01-09 Medtronic, Inc. Medical device to provide breathing therapy
US8509902B2 (en) 2011-07-28 2013-08-13 Medtronic, Inc. Medical device to provide breathing therapy
US20150039045A1 (en) 2011-08-11 2015-02-05 Inspire Medical Systems, Inc. Method and system for applying stimulation in treating sleep disordered breathing
US20130053717A1 (en) * 2011-08-30 2013-02-28 Nellcor Puritan Bennett Llc Automatic ventilator challenge to induce spontaneous breathing efforts
US8934992B2 (en) 2011-09-01 2015-01-13 Inspire Medical Systems, Inc. Nerve cuff
US8855783B2 (en) 2011-09-09 2014-10-07 Enopace Biomedical Ltd. Detector-based arterial stimulation
GB201116860D0 (en) * 2011-09-30 2011-11-09 Guy S And St Thomas Nhs Foundation Trust Patent monitoring method and monitoring device
US9364624B2 (en) 2011-12-07 2016-06-14 Covidien Lp Methods and systems for adaptive base flow
US9498589B2 (en) 2011-12-31 2016-11-22 Covidien Lp Methods and systems for adaptive base flow and leak compensation
CA2863049C (en) 2012-01-26 2017-08-29 Willard Wilson Neural monitoring methods and systems for treating pharyngeal disorders
US20130204155A1 (en) * 2012-01-27 2013-08-08 Mayo Foundation For Medical Education And Research Anesthesia Monitoring Systems and Methods of Monitoring Anesthesia
US20130197386A1 (en) * 2012-01-31 2013-08-01 Medtronic, Inc. Respiratory function detection
EP3228351B1 (en) 2012-03-05 2019-06-05 Lungpacer Medical Inc. Transvascular nerve stimulation apparatus
US8844526B2 (en) 2012-03-30 2014-09-30 Covidien Lp Methods and systems for triggering with unknown base flow
EP2846787B1 (en) * 2012-05-08 2018-08-29 Aeromics, Inc. Compounds for use in the treatment of aquaporin-mediated diseases
EP4233953A3 (en) 2012-06-21 2023-11-01 Lungpacer Medical Inc. Transvascular diaphragm pacing systems
WO2014008171A1 (en) * 2012-07-02 2014-01-09 Medisci L.L.C. Method and device for respiratory and cardiorespiratory support
US10362967B2 (en) 2012-07-09 2019-07-30 Covidien Lp Systems and methods for missed breath detection and indication
CN104661588B (en) * 2012-07-27 2017-03-08 心脏起搏器股份公司 Heart failure patient is layered
CN102949770B (en) * 2012-11-09 2015-04-22 张红璇 External diaphragm pacing and breathing machine synergistic air supply method and device thereof
US10335592B2 (en) 2012-12-19 2019-07-02 Viscardia, Inc. Systems, devices, and methods for improving hemodynamic performance through asymptomatic diaphragm stimulation
WO2014099820A1 (en) * 2012-12-19 2014-06-26 Inovise Medical, Inc. Hemodynamic performance enhancement through asymptomatic diaphragm stimulation
CN103055417B (en) * 2012-12-31 2015-09-09 中国人民解放军第三军医大学第一附属医院 A kind of noinvasive transcutaneous electrostimulation instrument
US20170112409A1 (en) * 2013-02-06 2017-04-27 BTS S.p.A. Wireless probe for dental electromyography
US9981096B2 (en) 2013-03-13 2018-05-29 Covidien Lp Methods and systems for triggering with unknown inspiratory flow
TWI505812B (en) * 2013-04-15 2015-11-01 Chi Mei Comm Systems Inc System and method for displaying analysis of breath
US9295397B2 (en) 2013-06-14 2016-03-29 Massachusetts Institute Of Technology Method and apparatus for beat-space frequency domain prediction of cardiovascular death after acute coronary event
US9743889B2 (en) 2013-08-05 2017-08-29 Cardiac Pacemakers, Inc. System and method for detecting worsening of heart failure based on rapid shallow breathing index
WO2015021348A2 (en) 2013-08-09 2015-02-12 Inspire Medical Systems, Inc. Patient control for implantable medical device
EP2839859B1 (en) * 2013-08-20 2016-04-27 Sorin CRM SAS Active medical device, in particular a CRT resynchroniser, including predictive warning means for cardiac decompensation in the presence of central sleep apnoea
EP3052017B1 (en) * 2013-10-02 2019-12-11 The Board of Trustees of the University of Illionis Organ mounted electronics
SG11201604153UA (en) 2013-11-06 2016-07-28 Aeromics Inc Novel formulations
EP3071288B1 (en) 2013-11-19 2018-11-14 The Cleveland Clinic Foundation System for treating obstructive sleep apnea using a neuromuscular stimulator
EP3071285B1 (en) 2013-11-22 2020-06-03 Lungpacer Medical Inc. Apparatus for assisted breathing by transvascular nerve stimulation
WO2015095969A1 (en) * 2013-12-27 2015-07-02 St. Michael's Hospital Device, method and system for providing ventilatory assist to a patient
CA2935454A1 (en) * 2014-01-21 2015-07-30 Simon Fraser University Systems and related methods for optimization of multi-electrode nerve pacing
US11383083B2 (en) 2014-02-11 2022-07-12 Livanova Usa, Inc. Systems and methods of detecting and treating obstructive sleep apnea
TWI645835B (en) * 2014-02-25 2019-01-01 萊鎂醫療器材股份有限公司 Breathing airflow detecting device, method and application thereof
CN103800999A (en) * 2014-02-25 2014-05-21 郑州雅晨生物科技有限公司 Obstructive sleep apnea hypopnea syndrome therapeutic apparatus
MX366801B (en) * 2014-02-28 2019-07-24 Powell Mansfield Inc Systems, methods and devices for sensing emg activity.
US20150283382A1 (en) * 2014-04-04 2015-10-08 Med-El Elektromedizinische Geraete Gmbh Respiration Sensors For Recording Of Triggered Respiratory Signals In Neurostimulators
CN106659481A (en) 2014-07-22 2017-05-10 帝人制药株式会社 Heart failure evaluation method and diagnosis device
US9659159B2 (en) 2014-08-14 2017-05-23 Sleep Data Services, Llc Sleep data chain of custody
US9808591B2 (en) 2014-08-15 2017-11-07 Covidien Lp Methods and systems for breath delivery synchronization
WO2016033245A1 (en) 2014-08-26 2016-03-03 Rmx, Llc Devices and methods for reducing intrathoracic pressure
US10172593B2 (en) 2014-09-03 2019-01-08 Earlysense Ltd. Pregnancy state monitoring
US10802780B2 (en) * 2014-10-08 2020-10-13 Lg Electronics Inc. Digital device and method for controlling same
EP3206567A1 (en) 2014-10-13 2017-08-23 Glusense, Ltd. Analyte-sensing device
US9950129B2 (en) 2014-10-27 2018-04-24 Covidien Lp Ventilation triggering using change-point detection
EP3212277B1 (en) 2014-10-31 2020-12-16 Avent, Inc. Non-invasive nerve stimulation system
US9925346B2 (en) 2015-01-20 2018-03-27 Covidien Lp Systems and methods for ventilation with unknown exhalation flow
EP3064131A1 (en) 2015-03-03 2016-09-07 BIOTRONIK SE & Co. KG Combined vagus-phrenic nerve stimulation apparatus
CN113908438A (en) 2015-03-19 2022-01-11 启迪医疗仪器公司 Stimulation for treating sleep disordered breathing
US9839786B2 (en) 2015-04-17 2017-12-12 Inspire Medical Systems, Inc. System and method of monitoring for and reporting on patient-made stimulation therapy programming changes
CN108135535B (en) * 2015-08-11 2021-01-05 皇家飞利浦有限公司 Device and method for processing electromyographic signals relating to respiratory activity
US10932714B2 (en) 2016-01-20 2021-03-02 Soniphi Llc Frequency analysis feedback systems and methods
EP3445872A1 (en) 2016-04-20 2019-02-27 Glusense Ltd. Fret-based glucose-detection molecules
CN105748069B (en) * 2016-04-21 2018-10-23 罗远明 A kind of centric sleep apnea carbon dioxide inhalation therapy device
CN105879223B (en) * 2016-04-22 2017-02-08 广州雪利昂生物科技有限公司 Method and apparatus for triggering external diaphragm pacemaker by using surface electromyogram signal as synchronization signal
US10369361B2 (en) 2016-04-29 2019-08-06 Viscardia, Inc. Leads for implantable medical device that affects pressures within the intrathoracic cavity through diaphragmatic stimulation
US11247039B2 (en) 2016-05-03 2022-02-15 Btl Healthcare Technologies A.S. Device including RF source of energy and vacuum system
US10583287B2 (en) 2016-05-23 2020-03-10 Btl Medical Technologies S.R.O. Systems and methods for tissue treatment
US10556122B1 (en) 2016-07-01 2020-02-11 Btl Medical Technologies S.R.O. Aesthetic method of biological structure treatment by magnetic field
EP3487457B1 (en) * 2016-07-25 2023-09-06 Facebook Technologies, LLC. Adaptive system for deriving control signals from measurements of neuromuscular activity
CN109562263B (en) * 2016-08-01 2022-05-31 Med-El电气医疗器械有限公司 Respiration triggered parasternal myoelectric recording in a neurostimulator
US11052241B2 (en) * 2016-11-03 2021-07-06 West Affum Holdings Corp. Wearable cardioverter defibrillator (WCD) system measuring patient's respiration
WO2018089789A1 (en) 2016-11-10 2018-05-17 The Research Foundation For The State University Of New York System, method and biomarkers for airway obstruction
US11426513B2 (en) * 2016-11-29 2022-08-30 Geoffrey Louis Tyson Implantable devices for drug delivery in response to detected biometric parameters associated with an opioid drug overdose and associated systems and methods
CN107019495B (en) * 2017-03-13 2019-11-29 北京航空航天大学 Apnea detection and prior-warning device and method based on smart phone and the mounted respiration transducer of nose
WO2018200470A1 (en) 2017-04-29 2018-11-01 Cardiac Pacemakers, Inc. Heart failure event rate assessment
US10293164B2 (en) 2017-05-26 2019-05-21 Lungpacer Medical Inc. Apparatus and methods for assisted breathing by transvascular nerve stimulation
EP3760280A1 (en) * 2017-06-16 2021-01-06 Alphatec Spine, Inc. Systems, methods, and devices for detecting the threshold of nerve-muscle response using variable frequency stimulation
CN111163834A (en) 2017-06-30 2020-05-15 隆佩瑟尔医疗公司 Device for preventing, reducing and/or treating cognitive impairment
US10195429B1 (en) 2017-08-02 2019-02-05 Lungpacer Medical Inc. Systems and methods for intravascular catheter positioning and/or nerve stimulation
US10940308B2 (en) 2017-08-04 2021-03-09 Lungpacer Medical Inc. Systems and methods for trans-esophageal sympathetic ganglion recruitment
AU2018316277B2 (en) 2017-08-11 2023-12-07 Inspire Medical Systems, Inc. Cuff electrode
WO2019046547A1 (en) 2017-08-31 2019-03-07 Mayo Foundation For Medical Education And Research Systems and methods for controlling breathing
CN108174034A (en) * 2017-12-27 2018-06-15 苏鹏霄 Using the system and method for APP real time monitoring sacral nerve neuromodulation devices
US11031134B2 (en) * 2018-02-05 2021-06-08 International Business Machines Corporation Monitoring individuals for water retention management
US11058349B2 (en) 2018-03-24 2021-07-13 Ovadia Sagiv Non-invasive handling of sleep apnea, snoring and emergency situations
US10722710B2 (en) 2018-03-24 2020-07-28 Moshe Hayik Secretion clearance and cough assist
WO2019189153A1 (en) * 2018-03-26 2019-10-03 テルモ株式会社 Support system, support method, support program, and recording medium on which support program is recorded
US11109787B2 (en) * 2018-05-21 2021-09-07 Vine Medical LLC Multi-tip probe for obtaining bioelectrical measurements
US11771899B2 (en) 2018-07-10 2023-10-03 The Cleveland Clinic Foundation System and method for treating obstructive sleep apnea
EP3877043A4 (en) 2018-11-08 2022-08-24 Lungpacer Medical Inc. Stimulation systems and related user interfaces
EP3877024A4 (en) 2018-11-10 2022-08-10 Novaresp Technologies Inc. Method and apparatus for continuous management of airway pressure for detection and/or prediction of respiratory failure
US11894139B1 (en) 2018-12-03 2024-02-06 Patientslikeme Llc Disease spectrum classification
US11471683B2 (en) 2019-01-29 2022-10-18 Synapse Biomedical, Inc. Systems and methods for treating sleep apnea using neuromodulation
US11382563B2 (en) 2019-03-01 2022-07-12 Respiration AI, LLC System and method for detecting ventilatory depression and for prompting a patient to breathe
US11547307B2 (en) * 2019-04-29 2023-01-10 Technion Research And Development Foundation Ltd. Quantification of the respiratory effort from hemodynamic measurements
ES2956271T3 (en) 2019-05-02 2023-12-18 Xii Medical Inc Implantable stimulation power receiver and systems
JP2022532375A (en) 2019-05-16 2022-07-14 ラングペーサー メディカル インコーポレイテッド Systems and methods for detection and stimulation
US20200375665A1 (en) * 2019-05-31 2020-12-03 Canon U.S.A., Inc. Medical continuum robot and methods thereof
JP2022536478A (en) 2019-06-12 2022-08-17 ラングペーサー メディカル インコーポレイテッド Circuits for medical stimulation systems
US11266838B1 (en) 2019-06-21 2022-03-08 Rmx, Llc Airway diagnostics utilizing phrenic nerve stimulation device and method
US11324954B2 (en) 2019-06-28 2022-05-10 Covidien Lp Achieving smooth breathing by modified bilateral phrenic nerve pacing
KR20210024874A (en) 2019-08-26 2021-03-08 삼성전자주식회사 Monitoring device inserted into human body and operating method thereof
US11925803B2 (en) 2019-09-26 2024-03-12 Viscardia, Inc. Implantable medical systems, devices, and methods for affecting cardiac function through diaphragm stimulation, and for monitoring diaphragmatic health
WO2021076188A1 (en) 2019-10-15 2021-04-22 Enhale Medical, Inc. Biased neuromodulation lead and method of using same
WO2021141950A1 (en) * 2020-01-06 2021-07-15 W. L. Gore & Associates, Inc. Conditioning algorithms for biomarker sensor measurements
WO2021168588A1 (en) * 2020-02-26 2021-09-02 Novaresp Technologies Inc. Method and apparatus for determining and/or predicting sleep and respiratory behaviours for management of airway pressure
US11878167B2 (en) 2020-05-04 2024-01-23 Btl Healthcare Technologies A.S. Device and method for unattended treatment of a patient
BR112022022112A2 (en) 2020-05-04 2022-12-13 Btl Healthcare Tech A S DEVICE FOR UNASSISTED PATIENT TREATMENT
US11672934B2 (en) 2020-05-12 2023-06-13 Covidien Lp Remote ventilator adjustment
US11691010B2 (en) 2021-01-13 2023-07-04 Xii Medical, Inc. Systems and methods for improving sleep disordered breathing
AU2022227086A1 (en) * 2021-02-24 2023-09-28 Medtronic, Inc. Electrode selection based on impedance for sensing or stimulation
US11896816B2 (en) 2021-11-03 2024-02-13 Btl Healthcare Technologies A.S. Device and method for unattended treatment of a patient
CN114376559B (en) * 2022-01-18 2023-09-19 高昌生医股份有限公司 Respiratory datum line tracking acceleration method
WO2024035578A2 (en) * 2022-08-11 2024-02-15 Stimdia Medical, Inc. Apparatus and method for diaphragm stimulation

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5540733A (en) * 1994-09-21 1996-07-30 Medtronic, Inc. Method and apparatus for detecting and treating obstructive sleep apnea
US6224562B1 (en) * 1998-06-11 2001-05-01 Cprx Llc Methods and devices for performing cardiopulmonary resuscitation

Family Cites Families (197)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US56519A (en) * 1866-07-24 Improvement in clamps for holding saws
US65567A (en) * 1867-06-11 Improved soeew machine
US142815A (en) * 1873-09-16 Improvement in car-couplings
US176809A (en) * 1876-05-02 Improvement in machinery for cutting waved edges on leather
US146918A (en) * 1874-01-27 Improvement in car-couplings
US540732A (en) * 1895-06-11 Martin freund
US59240A (en) * 1866-10-30 Maeshall t
US61315A (en) * 1867-01-22 Improved apparatus for decomposing animal and vegetable substances
US540731A (en) * 1895-06-11 Wire-reel
US85869A (en) * 1869-01-12 Improvement in horse-rakes
US85867A (en) * 1869-01-12 Improvement in blind-fastener
US85868A (en) * 1869-01-12 Improvement in steam water-elevators
US74741A (en) * 1868-02-18 George w
US138719A (en) * 1873-05-06 Improvement in fly-switches
US21795A (en) * 1858-10-12 Improvement in cotton-gins
US204213A (en) * 1878-05-28 Improvement in loom-pickers
US115561A (en) * 1871-06-06 Improvement in electro-sviagnetic separators
US61319A (en) * 1867-01-22 Improvement in pumps
US193697A (en) * 1877-07-31 Improvement in mowers
US240240A (en) * 1881-04-19 Beer-faucet
US215082A (en) * 1879-05-06 Improvement in type-writing machines
US155341A (en) * 1874-09-22 Improvement in fertilizers
US36294A (en) * 1862-08-26 Improved portable sugar-evaporatx
US119711A (en) * 1871-10-10 Improvement in staple-machines
US149334A (en) * 1874-04-07 Improvement in railroad-frogs
US211173A (en) * 1879-01-07 Improvement in wagon-tracks for roads
US540733A (en) * 1895-06-11 Ernst gerstenberg and herman barghausen
US247729A (en) * 1881-09-27 Corset-stay
US101833A (en) * 1870-04-12 Improved coal-box
US122622A (en) * 1872-01-09 Improvement in compartment-cars for railways
US522862A (en) * 1894-07-10 Sawhorse
US77953A (en) * 1868-05-19 b i c k e
US300094A (en) * 1884-06-10 Machine
US127091A (en) * 1872-05-21 Improvement in spark-arresters
US39745A (en) * 1863-09-01 Improvement in hoisting apparatus
US85734A (en) * 1869-01-12 Improvement in gr
US345202A (en) * 1886-07-06 Treating lac
US281219A (en) * 1883-07-10 Half to alonzo e
US167523A (en) * 1875-09-07 Improvement in sole-channeling machines
US174287A (en) * 1876-02-29 Improvement in tool-holders
US111040A (en) * 1871-01-17 Improvement in fluid-meters
US225226A (en) * 1880-03-09 Rotary engine
US237963A (en) * 1881-02-22 Manufacture of sheet-iron
US65563A (en) * 1867-06-11 Julius hackert
US85865A (en) * 1869-01-12 Improvement in threshing-knives
US85866A (en) * 1869-01-12 Improved bed-bottom
US61320A (en) * 1867-01-22 of lewiston
US574507A (en) * 1897-01-05 Account-keeping book
US148897A (en) * 1874-03-24 Improvement in machines for pressing pantaloons
US88015A (en) * 1869-03-23 Improvement in lifting-jacks
US99479A (en) * 1870-02-01 Edwin r
US55060A (en) * 1866-05-29 Improvement in harvester-rakes
US681192A (en) * 1900-11-19 1901-08-27 Natural Food Company Marking-machine.
US678535A (en) * 1901-02-02 1901-07-16 Austen Bigg Hoe.
US911218A (en) * 1908-02-17 1909-02-02 Elias B Wrenn Trace-holder.
US1496918A (en) * 1922-08-23 1924-06-10 Frederick M Baldwin Signaling device for vehicles
US3773051A (en) 1972-03-01 1973-11-20 Research Corp Method and apparatus for stimulation of body tissue
US4146918A (en) * 1978-01-18 1979-03-27 Albert Tureck Photographic flash reflector and diffuser system
US4827935A (en) * 1986-04-24 1989-05-09 Purdue Research Foundation Demand electroventilator
US4830008A (en) * 1987-04-24 1989-05-16 Meer Jeffrey A Method and system for treatment of sleep apnea
US5329931A (en) * 1989-02-21 1994-07-19 William L. Clauson Apparatus and method for automatic stimulation of mammals in response to blood gas analysis
US5265604A (en) 1990-05-14 1993-11-30 Vince Dennis J Demand - diaphragmatic pacing (skeletal muscle pressure modified)
US5056519A (en) 1990-05-14 1991-10-15 Vince Dennis J Unilateral diaphragmatic pacer
US5281219A (en) 1990-11-23 1994-01-25 Medtronic, Inc. Multiple stimulation electrodes
DE69209324T2 (en) 1991-01-09 1996-11-21 Medtronic Inc Servo control for muscles
US5211173A (en) 1991-01-09 1993-05-18 Medtronic, Inc. Servo muscle control
US5190036A (en) * 1991-02-28 1993-03-02 Linder Steven H Abdominal binder for effectuating cough stimulation
US5146918A (en) * 1991-03-19 1992-09-15 Medtronic, Inc. Demand apnea control of central and obstructive sleep apnea
US5215082A (en) 1991-04-02 1993-06-01 Medtronic, Inc. Implantable apnea generator with ramp on generator
US5174287A (en) 1991-05-28 1992-12-29 Medtronic, Inc. Airway feedback measurement system responsive to detected inspiration and obstructive apnea event
US5233983A (en) 1991-09-03 1993-08-10 Medtronic, Inc. Method and apparatus for apnea patient screening
US5572543A (en) 1992-04-09 1996-11-05 Deutsch Aerospace Ag Laser system with a micro-mechanically moved mirror
US5423372A (en) * 1993-12-27 1995-06-13 Ford Motor Company Joining sand cores for making castings
US5800470A (en) 1994-01-07 1998-09-01 Medtronic, Inc. Respiratory muscle electromyographic rate responsive pacemaker
US5524632A (en) 1994-01-07 1996-06-11 Medtronic, Inc. Method for implanting electromyographic sensing electrodes
US5546952A (en) 1994-09-21 1996-08-20 Medtronic, Inc. Method and apparatus for detection of a respiratory waveform
US5485851A (en) 1994-09-21 1996-01-23 Medtronic, Inc. Method and apparatus for arousal detection
US5483969A (en) * 1994-09-21 1996-01-16 Medtronic, Inc. Method and apparatus for providing a respiratory effort waveform for the treatment of obstructive sleep apnea
US5522862A (en) * 1994-09-21 1996-06-04 Medtronic, Inc. Method and apparatus for treating obstructive sleep apnea
US5540732A (en) 1994-09-21 1996-07-30 Medtronic, Inc. Method and apparatus for impedance detecting and treating obstructive airway disorders
US5540731A (en) 1994-09-21 1996-07-30 Medtronic, Inc. Method and apparatus for pressure detecting and treating obstructive airway disorders
US5549655A (en) 1994-09-21 1996-08-27 Medtronic, Inc. Method and apparatus for synchronized treatment of obstructive sleep apnea
US5678535A (en) 1995-04-21 1997-10-21 Dimarco; Anthony Fortunato Method and apparatus for electrical stimulation of the respiratory muscles to achieve artificial ventilation in a patient
FR2739760B1 (en) * 1995-10-11 1997-12-12 Salomon Sa METHOD AND DEVICE FOR HEATING AN INTERIOR SHOE LINING
FR2739782B1 (en) * 1995-10-13 1997-12-19 Ela Medical Sa ACTIVE IMPLANTABLE MEDICAL DEVICE, IN PARTICULAR HEART STIMULATOR, WITH CONTROLLED OPERATION AND REDUCED CONSUMPTION
US6006134A (en) * 1998-04-30 1999-12-21 Medtronic, Inc. Method and device for electronically controlling the beating of a heart using venous electrical stimulation of nerve fibers
US5944680A (en) 1996-06-26 1999-08-31 Medtronic, Inc. Respiratory effort detection method and apparatus
US6021352A (en) 1996-06-26 2000-02-01 Medtronic, Inc, Diagnostic testing methods and apparatus for implantable therapy devices
US6099479A (en) 1996-06-26 2000-08-08 Medtronic, Inc. Method and apparatus for operating therapy system
US6132384A (en) 1996-06-26 2000-10-17 Medtronic, Inc. Sensor, method of sensor implant and system for treatment of respiratory disorders
US5895360A (en) * 1996-06-26 1999-04-20 Medtronic, Inc. Gain control for a periodic signal and method regarding same
SE9603841D0 (en) 1996-10-18 1996-10-18 Pacesetter Ab A tissue stimulating apparatus
US5830008A (en) 1996-12-17 1998-11-03 The Whitaker Corporation Panel mountable connector
US5876353A (en) * 1997-01-31 1999-03-02 Medtronic, Inc. Impedance monitor for discerning edema through evaluation of respiratory rate
US5797923A (en) 1997-05-12 1998-08-25 Aiyar; Harish Electrode delivery instrument
CA2306918C (en) 1997-10-17 2008-04-15 Respironics, Inc. Muscle stimulating device and method for diagnosing and treating a breathing disorder
US6021362A (en) * 1998-02-17 2000-02-01 Maggard; Karl J. Method and apparatus for dispensing samples and premiums
US6269269B1 (en) 1998-04-23 2001-07-31 Medtronic Inc. Method and apparatus for synchronized treatment of obstructive sleep apnea
US6251126B1 (en) * 1998-04-23 2001-06-26 Medtronic Inc Method and apparatus for synchronized treatment of obstructive sleep apnea
AU760048B2 (en) 1998-05-06 2003-05-08 Genentech Inc. Protein purification by ion exchange chromatography
AUPP366398A0 (en) 1998-05-22 1998-06-18 Resmed Limited Ventilatory assistance for treatment of cardiac failure and cheyne-stokes breathing
US6463327B1 (en) * 1998-06-11 2002-10-08 Cprx Llc Stimulatory device and methods to electrically stimulate the phrenic nerve
US6312399B1 (en) 1998-06-11 2001-11-06 Cprx, Llc Stimulatory device and methods to enhance venous blood return during cardiopulmonary resuscitation
SE9802335D0 (en) 1998-06-30 1998-06-30 Siemens Elema Ab Breathing Help System
FR2780654B1 (en) 1998-07-06 2000-12-01 Ela Medical Sa ACTIVE IMPLANTABLE MEDICAL DEVICE FOR ELECTROSTIMULATION TREATMENT OF SLEEP APNEA SYNDROME
US6587725B1 (en) * 1998-07-27 2003-07-01 Dominique Durand Method and apparatus for closed-loop stimulation of the hypoglossal nerve in human patients to treat obstructive sleep apnea
US6240316B1 (en) 1998-08-14 2001-05-29 Advanced Bionics Corporation Implantable microstimulation system for treatment of sleep apnea
US6212435B1 (en) * 1998-11-13 2001-04-03 Respironics, Inc. Intraoral electromuscular stimulation device and method
US7117032B2 (en) 1999-03-01 2006-10-03 Quantum Intech, Inc. Systems and methods for facilitating physiological coherence using respiration training
US7577475B2 (en) * 1999-04-16 2009-08-18 Cardiocom System, method, and apparatus for combining information from an implanted device with information from a patient monitoring apparatus
US6314324B1 (en) 1999-05-05 2001-11-06 Respironics, Inc. Vestibular stimulation system and method
US6512949B1 (en) * 1999-07-12 2003-01-28 Medtronic, Inc. Implantable medical device for measuring time varying physiologic conditions especially edema and for responding thereto
US6600949B1 (en) * 1999-11-10 2003-07-29 Pacesetter, Inc. Method for monitoring heart failure via respiratory patterns
US6480733B1 (en) 1999-11-10 2002-11-12 Pacesetter, Inc. Method for monitoring heart failure
US6527729B1 (en) * 1999-11-10 2003-03-04 Pacesetter, Inc. Method for monitoring patient using acoustic sensor
US6336903B1 (en) 1999-11-16 2002-01-08 Cardiac Intelligence Corp. Automated collection and analysis patient care system and method for diagnosing and monitoring congestive heart failure and outcomes thereof
US6752765B1 (en) * 1999-12-01 2004-06-22 Medtronic, Inc. Method and apparatus for monitoring heart rate and abnormal respiration
US6415183B1 (en) * 1999-12-09 2002-07-02 Cardiac Pacemakers, Inc. Method and apparatus for diaphragmatic pacing
US6418346B1 (en) * 1999-12-14 2002-07-09 Medtronic, Inc. Apparatus and method for remote therapy and diagnosis in medical devices via interface systems
US20030127091A1 (en) * 1999-12-15 2003-07-10 Chang Yung Chi Scientific respiration for self-health-care
US6710094B2 (en) * 1999-12-29 2004-03-23 Styrochem Delaware, Inc. Processes for preparing patterns for use in metal castings
US6589188B1 (en) * 2000-05-05 2003-07-08 Pacesetter, Inc. Method for monitoring heart failure via respiratory patterns
US6735479B2 (en) 2000-06-14 2004-05-11 Medtronic, Inc. Lifestyle management system
US6666830B1 (en) 2000-08-17 2003-12-23 East River Ventures, Lp System and method for detecting the onset of an obstructive sleep apnea event
US6357438B1 (en) * 2000-10-19 2002-03-19 Mallinckrodt Inc. Implantable sensor for proportional assist ventilation
US6633779B1 (en) 2000-11-27 2003-10-14 Science Medicus, Inc. Treatment of asthma and respiratory disease by means of electrical neuro-receptive waveforms
US6641542B2 (en) * 2001-04-30 2003-11-04 Medtronic, Inc. Method and apparatus to detect and treat sleep respiratory events
US7206635B2 (en) 2001-06-07 2007-04-17 Medtronic, Inc. Method and apparatus for modifying delivery of a therapy in response to onset of sleep
US6731984B2 (en) * 2001-06-07 2004-05-04 Medtronic, Inc. Method for providing a therapy to a patient involving modifying the therapy after detecting an onset of sleep in the patient, and implantable medical device embodying same
US6572949B1 (en) * 2001-08-30 2003-06-03 Carlton Paul Lewis Paint mask and method of using
FR2829917B1 (en) 2001-09-24 2004-06-11 Ela Medical Sa ACTIVE MEDICAL DEVICE INCLUDING MEANS FOR DIAGNOSING THE RESPIRATORY PROFILE
US6904320B2 (en) * 2002-02-14 2005-06-07 Pacesetter, Inc. Sleep apnea therapy device using dynamic overdrive pacing
US6999817B2 (en) 2002-02-14 2006-02-14 Packsetter, Inc. Cardiac stimulation device including sleep apnea prevention and treatment
US6928324B2 (en) 2002-02-14 2005-08-09 Pacesetter, Inc. Stimulation device for sleep apnea prevention, detection and treatment
US8391989B2 (en) * 2002-12-18 2013-03-05 Cardiac Pacemakers, Inc. Advanced patient management for defining, identifying and using predetermined health-related events
US20030195571A1 (en) 2002-04-12 2003-10-16 Burnes John E. Method and apparatus for the treatment of central sleep apnea using biventricular pacing
US20030204213A1 (en) 2002-04-30 2003-10-30 Jensen Donald N. Method and apparatus to detect and monitor the frequency of obstructive sleep apnea
US20030225339A1 (en) 2002-05-06 2003-12-04 Respironics Novametrix Methods for inducing temporary changes in ventilation for estimation of hemodynamic performance
US6881192B1 (en) * 2002-06-12 2005-04-19 Pacesetter, Inc. Measurement of sleep apnea duration and evaluation of response therapies using duration metrics
SE0202537D0 (en) * 2002-08-28 2002-08-28 Siemens Elema Ab Nerve stimulation apparatus
JP4095391B2 (en) * 2002-09-24 2008-06-04 キヤノン株式会社 Position detection method
JP4309111B2 (en) * 2002-10-02 2009-08-05 株式会社スズケン Health management system, activity state measuring device and data processing device
US6945939B2 (en) * 2002-10-18 2005-09-20 Pacesetter, Inc. Hemodynamic analysis
US7277757B2 (en) * 2002-10-31 2007-10-02 Medtronic, Inc. Respiratory nerve stimulation
US7252640B2 (en) * 2002-12-04 2007-08-07 Cardiac Pacemakers, Inc. Detection of disordered breathing
US8672852B2 (en) * 2002-12-13 2014-03-18 Intercure Ltd. Apparatus and method for beneficial modification of biorhythmic activity
US7025730B2 (en) * 2003-01-10 2006-04-11 Medtronic, Inc. System and method for automatically monitoring and delivering therapy for sleep-related disordered breathing
US7160252B2 (en) * 2003-01-10 2007-01-09 Medtronic, Inc. Method and apparatus for detecting respiratory disturbances
US7438686B2 (en) * 2003-01-10 2008-10-21 Medtronic, Inc. Apparatus and method for monitoring for disordered breathing
US20050020240A1 (en) * 2003-02-07 2005-01-27 Darin Minter Private wireless network
US20050261747A1 (en) 2003-05-16 2005-11-24 Schuler Eleanor L Method and system to control respiration by means of neuro-electrical coded signals
EP1660177A4 (en) * 2003-07-23 2010-03-03 Univ Cleveland Hospitals Mapping probe system for neuromuscular electrical stimulation apparatus
WO2005009291A2 (en) * 2003-07-23 2005-02-03 Synapse Biomedical, Inc. System and method for conditioning a diaphragm of a patient
US7662101B2 (en) * 2003-09-18 2010-02-16 Cardiac Pacemakers, Inc. Therapy control based on cardiopulmonary status
EP1670547B1 (en) * 2003-08-18 2008-11-12 Cardiac Pacemakers, Inc. Patient monitoring system
US7532934B2 (en) * 2003-09-18 2009-05-12 Cardiac Pacemakers, Inc. Snoring detection system and method
US7757690B2 (en) * 2003-09-18 2010-07-20 Cardiac Pacemakers, Inc. System and method for moderating a therapy delivered during sleep using physiologic data acquired during non-sleep
US7610094B2 (en) * 2003-09-18 2009-10-27 Cardiac Pacemakers, Inc. Synergistic use of medical devices for detecting medical disorders
US7591265B2 (en) * 2003-09-18 2009-09-22 Cardiac Pacemakers, Inc. Coordinated use of respiratory and cardiac therapies for sleep disordered breathing
US7720541B2 (en) * 2003-08-18 2010-05-18 Cardiac Pacemakers, Inc. Adaptive therapy for disordered breathing
US7469697B2 (en) * 2003-09-18 2008-12-30 Cardiac Pacemakers, Inc. Feedback system and method for sleep disordered breathing therapy
US7510531B2 (en) * 2003-09-18 2009-03-31 Cardiac Pacemakers, Inc. System and method for discrimination of central and obstructive disordered breathing events
US7396333B2 (en) * 2003-08-18 2008-07-08 Cardiac Pacemakers, Inc. Prediction of disordered breathing
US7468040B2 (en) * 2003-09-18 2008-12-23 Cardiac Pacemakers, Inc. Methods and systems for implantably monitoring external breathing therapy
US7680537B2 (en) * 2003-08-18 2010-03-16 Cardiac Pacemakers, Inc. Therapy triggered by prediction of disordered breathing
US7664546B2 (en) * 2003-09-18 2010-02-16 Cardiac Pacemakers, Inc. Posture detection system and method
EP1512430B1 (en) * 2003-09-02 2008-02-13 Biotronik GmbH & Co. KG Device for sleep-apnea treatment
US20050055060A1 (en) * 2003-09-05 2005-03-10 Steve Koh Determination of respiratory characteristics from AV conduction intervals
US6905788B2 (en) * 2003-09-12 2005-06-14 Eastman Kodak Company Stabilized OLED device
US20050065563A1 (en) * 2003-09-23 2005-03-24 Avram Scheiner Paced ventilation therapy by an implantable cardiac device
US8160711B2 (en) 2003-10-15 2012-04-17 Rmx, Llc Multimode device and method for controlling breathing
US7970475B2 (en) * 2003-10-15 2011-06-28 Rmx, Llc Device and method for biasing lung volume
US8467876B2 (en) * 2003-10-15 2013-06-18 Rmx, Llc Breathing disorder detection and therapy delivery device and method
US9259573B2 (en) * 2003-10-15 2016-02-16 Rmx, Llc Device and method for manipulating exhalation
US20080161878A1 (en) 2003-10-15 2008-07-03 Tehrani Amir J Device and method to for independently stimulating hemidiaphragms
US8140164B2 (en) * 2003-10-15 2012-03-20 Rmx, Llc Therapeutic diaphragm stimulation device and method
US20060167523A1 (en) * 2003-10-15 2006-07-27 Tehrani Amir J Device and method for improving upper airway functionality
US20120158091A1 (en) * 2003-10-15 2012-06-21 Rmx, Llc Therapeutic diaphragm stimulation device and method
US8244358B2 (en) * 2003-10-15 2012-08-14 Rmx, Llc Device and method for treating obstructive sleep apnea
US7979128B2 (en) * 2003-10-15 2011-07-12 Rmx, Llc Device and method for gradually controlling breathing
US8265759B2 (en) 2003-10-15 2012-09-11 Rmx, Llc Device and method for treating disorders of the cardiovascular system or heart
US6964641B2 (en) * 2003-12-24 2005-11-15 Medtronic, Inc. Implantable medical device with sleep disordered breathing monitoring
US7519425B2 (en) * 2004-01-26 2009-04-14 Pacesetter, Inc. Tiered therapy for respiratory oscillations characteristic of Cheyne-Stokes respiration
JP4809779B2 (en) 2004-02-05 2011-11-09 アーリーセンス・リミテッド Prediction and monitoring technology for clinical onset in respiration
US7070568B1 (en) * 2004-03-02 2006-07-04 Pacesetter, Inc. System and method for diagnosing and tracking congestive heart failure based on the periodicity of Cheyne-Stokes Respiration using an implantable medical device
DE102004016985B4 (en) 2004-04-07 2010-07-22 Pari Pharma Gmbh Aerosol generating device and inhalation device
US7082331B1 (en) * 2004-04-21 2006-07-25 Pacesetter, Inc. System and method for applying therapy during hyperpnea phase of periodic breathing using an implantable medical device
US7245971B2 (en) 2004-04-21 2007-07-17 Pacesetter, Inc. System and method for applying therapy during hyperpnea phase of periodic breathing using an implantable medical device
JP4396380B2 (en) 2004-04-26 2010-01-13 アイシン・エィ・ダブリュ株式会社 Traffic information transmission device and transmission method
US7153271B2 (en) 2004-05-20 2006-12-26 Airmatrix Technologies, Inc. Method and system for diagnosing central versus obstructive apnea
US20060058852A1 (en) * 2004-09-10 2006-03-16 Steve Koh Multi-variable feedback control of stimulation for inspiratory facilitation
US7678116B2 (en) * 2004-12-06 2010-03-16 Dfine, Inc. Bone treatment systems and methods
US20060122661A1 (en) * 2004-12-03 2006-06-08 Mandell Lee J Diaphragmatic pacing with activity monitor adjustment
US7680538B2 (en) 2005-03-31 2010-03-16 Case Western Reserve University Method of treating obstructive sleep apnea using electrical nerve stimulation
US8036750B2 (en) 2005-06-13 2011-10-11 Cardiac Pacemakers, Inc. System for neural control of respiration
US20080021506A1 (en) * 2006-05-09 2008-01-24 Massachusetts General Hospital Method and device for the electrical treatment of sleep apnea and snoring
US8280513B2 (en) 2006-12-22 2012-10-02 Rmx, Llc Device and method to treat flow limitations

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5540733A (en) * 1994-09-21 1996-07-30 Medtronic, Inc. Method and apparatus for detecting and treating obstructive sleep apnea
US6224562B1 (en) * 1998-06-11 2001-05-01 Cprx Llc Methods and devices for performing cardiopulmonary resuscitation

Also Published As

Publication number Publication date
US8467876B2 (en) 2013-06-18
US20050085867A1 (en) 2005-04-21
US8509901B2 (en) 2013-08-13
WO2005037172A2 (en) 2005-04-28
US20070021795A1 (en) 2007-01-25
US8116872B2 (en) 2012-02-14
DE112004001954T5 (en) 2006-10-26
WO2005037174A3 (en) 2005-06-09
WO2005037174A2 (en) 2005-04-28
WO2005037220A3 (en) 2005-07-07
US20080208281A1 (en) 2008-08-28
WO2005037173A2 (en) 2005-04-28
US20050085869A1 (en) 2005-04-21
US20130296973A1 (en) 2013-11-07
WO2005037172A3 (en) 2005-08-04
WO2005037077A3 (en) 2005-09-09
DE112004001957T5 (en) 2006-08-31
US20080188903A1 (en) 2008-08-07
DE112004001953T5 (en) 2006-10-26
US20050085734A1 (en) 2005-04-21
WO2005037220A2 (en) 2005-04-28
US8200336B2 (en) 2012-06-12
US20080183240A1 (en) 2008-07-31
US20130296964A1 (en) 2013-11-07
US20050085868A1 (en) 2005-04-21
US8348941B2 (en) 2013-01-08
US20050085866A1 (en) 2005-04-21
WO2005037077A2 (en) 2005-04-28
US20080183239A1 (en) 2008-07-31
US20060036294A1 (en) 2006-02-16
US20050085865A1 (en) 2005-04-21
US8255056B2 (en) 2012-08-28
WO2005037366A1 (en) 2005-04-28
DE112004001954B4 (en) 2015-10-22
US8412331B2 (en) 2013-04-02
US20060030894A1 (en) 2006-02-09

Similar Documents

Publication Publication Date Title
WO2005037173A3 (en) System and method for mapping diaphragm electrode sites
US6415185B1 (en) Objective programming and operation of a Cochlear implant based on measured evoked potentials that precede the stapedius reflex
CA2229656A1 (en) Digital automated current perception threshold (cpt) determination device
ATE533532T1 (en) ELECTRICAL NERVE STIMULATION BASED ON CHANNEL-SPECIFIC SAMPLING SEQUENCES
SE9901056D0 (en) Sensor system
WO2007117728A3 (en) Non-linear electrode array
WO2001082771A3 (en) Signal delivery through the right ventricular septum
DE50210133D1 (en) RETINA IMPLANT WITH ELECTRODE ARRANGEMENT FOR THE ELECTRICAL STIMULATION OF BIOLOGICAL MATERIAL
WO2005002665A3 (en) Apparatuses and systems for applying electrical stimulation to a patient
ATE295161T1 (en) ACTIVE MIXTURE IN VAGAL-INDUCED ASYSTOLY
ATE377440T1 (en) GASTRO STIMULATION DEVICE
WO2007057899A3 (en) Gait modulation system and method
ATE464027T1 (en) IMPLANTABLE MEDICAL DEVICE COMPRISING A CURVED FILM
EP2213331A3 (en) Cardiac rhythm management device with neural sensor
ATE310459T1 (en) DEVICE FOR DENERVATION OF THE INTRAOSSAL NERVE
DE69612020D1 (en) DEVICE AND METHOD FOR THE AUTOMATIC DETERMINATION OF STIMULATION PARAMETERS
AU2003293068A1 (en) Determining relative depolarization at multiple cardiac sites
SE0202537D0 (en) Nerve stimulation apparatus
AU2004310690A1 (en) Methods and systems for fitting a cochlear implant to a patient
ATE499919T1 (en) DEVICE FOR MEASURING AUDITIVE EVOKE POTENTIAL
EP0337642A3 (en) Transdermal drug delivery device
WO2007079015A3 (en) Method of and system for stabilization of sensors
AU5663101A (en) Apparatus and method for controlling the delivery of non-excitatory cardiac contractility modulating signals to heart
WO2002074385A3 (en) Device for surface stimulation of acupuncture points
SE9602846D0 (en) A stimulation device

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BW BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE EG ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NA NI NO NZ OM PG PH PL PT RO RU SC SD SE SG SK SL SY TJ TM TN TR TT TZ UA UG US UZ VC VN YU ZA ZM ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): BW GH GM KE LS MW MZ NA SD SL SZ TZ UG ZM ZW AM AZ BY KG KZ MD RU TJ TM AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LU MC NL PL PT RO SE SI SK TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
122 Ep: pct application non-entry in european phase