WO2005048933A3 - Oxime substituted imidazo ring compounds - Google Patents

Oxime substituted imidazo ring compounds Download PDF

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Publication number
WO2005048933A3
WO2005048933A3 PCT/US2004/037854 US2004037854W WO2005048933A3 WO 2005048933 A3 WO2005048933 A3 WO 2005048933A3 US 2004037854 W US2004037854 W US 2004037854W WO 2005048933 A3 WO2005048933 A3 WO 2005048933A3
Authority
WO
WIPO (PCT)
Prior art keywords
ring compounds
imidazo ring
compounds
substituted imidazo
oxime substituted
Prior art date
Application number
PCT/US2004/037854
Other languages
French (fr)
Other versions
WO2005048933A2 (en
Inventor
Tushar A Kshirsagar
Gregory D Lundquist Jr
David T Amos
Joseph F Dellaria Jr
Bernhard M Zimmermann
Philip D Heppner
Original Assignee
3M Innovative Properties Co
Tushar A Kshirsagar
Gregory D Lundquist Jr
David T Amos
Joseph F Dellaria Jr
Bernhard M Zimmermann
Philip D Heppner
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 3M Innovative Properties Co, Tushar A Kshirsagar, Gregory D Lundquist Jr, David T Amos, Joseph F Dellaria Jr, Bernhard M Zimmermann, Philip D Heppner filed Critical 3M Innovative Properties Co
Priority to CA002545774A priority Critical patent/CA2545774A1/en
Priority to JP2006539911A priority patent/JP2007511527A/en
Priority to EP04810872A priority patent/EP1685129A4/en
Priority to US10/595,792 priority patent/US7897767B2/en
Priority to AU2004291101A priority patent/AU2004291101A1/en
Publication of WO2005048933A2 publication Critical patent/WO2005048933A2/en
Publication of WO2005048933A3 publication Critical patent/WO2005048933A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00

Abstract

Imidazo ring compounds (e.g., imidazoquinolines, 6,7,8,9-tetrahydroimidazoquinolines, imidazonaphthyridines, and imidazopyridines) with an oxime substituent at the 2-position, pharmaceutical compositions containing the compounds, intermediates, and methods of use of these compounds as immunomodulators, for inducing cytokine biosynthesis in animals and in the treatment of diseases including viral and neoplastic diseases are disclosed.
PCT/US2004/037854 2003-11-14 2004-11-12 Oxime substituted imidazo ring compounds WO2005048933A2 (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
CA002545774A CA2545774A1 (en) 2003-11-14 2004-11-12 Oxime substituted imidazo ring compounds
JP2006539911A JP2007511527A (en) 2003-11-14 2004-11-12 Oxime-substituted imidazo ring compounds
EP04810872A EP1685129A4 (en) 2003-11-14 2004-11-12 Oxime substituted imidazo ring compounds
US10/595,792 US7897767B2 (en) 2003-11-14 2004-11-12 Oxime substituted imidazoquinolines
AU2004291101A AU2004291101A1 (en) 2003-11-14 2004-11-12 Oxime substituted imidazo ring compounds

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US52041803P 2003-11-14 2003-11-14
US60/520,418 2003-11-14

Publications (2)

Publication Number Publication Date
WO2005048933A2 WO2005048933A2 (en) 2005-06-02
WO2005048933A3 true WO2005048933A3 (en) 2005-12-01

Family

ID=34619463

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2004/037854 WO2005048933A2 (en) 2003-11-14 2004-11-12 Oxime substituted imidazo ring compounds

Country Status (7)

Country Link
US (1) US7897767B2 (en)
EP (1) EP1685129A4 (en)
JP (1) JP2007511527A (en)
CN (1) CN1906193A (en)
AU (1) AU2004291101A1 (en)
CA (1) CA2545774A1 (en)
WO (1) WO2005048933A2 (en)

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