WO2005051428A3 - Method for obtaining a thermoreversible gel with a controlled three-dimensional structure, and gel obtained - Google Patents

Method for obtaining a thermoreversible gel with a controlled three-dimensional structure, and gel obtained Download PDF

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Publication number
WO2005051428A3
WO2005051428A3 PCT/FR2004/050611 FR2004050611W WO2005051428A3 WO 2005051428 A3 WO2005051428 A3 WO 2005051428A3 FR 2004050611 W FR2004050611 W FR 2004050611W WO 2005051428 A3 WO2005051428 A3 WO 2005051428A3
Authority
WO
WIPO (PCT)
Prior art keywords
gel
obtaining
controlled
dimensional structure
thermoreversible
Prior art date
Application number
PCT/FR2004/050611
Other languages
French (fr)
Other versions
WO2005051428A2 (en
Inventor
Benedicte Lancon
Isabelle Coco
Eric Papon
Original Assignee
Rescoll
Benedicte Lancon
Isabelle Coco
Eric Papon
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34531387&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=WO2005051428(A3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Rescoll, Benedicte Lancon, Isabelle Coco, Eric Papon filed Critical Rescoll
Publication of WO2005051428A2 publication Critical patent/WO2005051428A2/en
Publication of WO2005051428A3 publication Critical patent/WO2005051428A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J3/00—Processes of treating or compounding macromolecular substances
    • C08J3/24—Crosslinking, e.g. vulcanising, of macromolecules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00—Polymeric products of isocyanates or isothiocyanates
    • C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/28—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the compounds used containing active hydrogen
    • C08G18/40—High-molecular-weight compounds
    • C08G18/48—Polyethers
    • C08G18/4833—Polyethers containing oxyethylene units
    • C08G18/4837—Polyethers containing oxyethylene units and other oxyalkylene units
    • C08G18/4841—Polyethers containing oxyethylene units and other oxyalkylene units containing oxyethylene end groups
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G2220/00—Compositions for preparing gels other than hydrogels, aerogels and xerogels
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J2371/00—Characterised by the use of polyethers obtained by reactions forming an ether link in the main chain; Derivatives of such polymers
    • C08J2371/02—Polyalkylene oxides

Abstract

The invention relates to a method for obtaining a thermoreversible gel, said method being characterised by the following steps: a selected quantity of poloxamer is mixed with a water-miscible solvent and a reagent selected from the isocyanate family in order to obtain an intermediate product, the intermediate product is mixed with water, and the evaporation of the solvent is triggered.
PCT/FR2004/050611 2003-11-24 2004-11-23 Method for obtaining a thermoreversible gel with a controlled three-dimensional structure, and gel obtained WO2005051428A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0350890 2003-11-24
FR0350890A FR2862652B1 (en) 2003-11-24 2003-11-24 PROCESS FOR OBTAINING THERMOREVERSIBLE GEL WITH THREE-DIMENSIONAL STRUCTURE CONTROLLED AND GEL OBTAINED

Publications (2)

Publication Number Publication Date
WO2005051428A2 WO2005051428A2 (en) 2005-06-09
WO2005051428A3 true WO2005051428A3 (en) 2005-07-28

Family

ID=34531387

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/FR2004/050611 WO2005051428A2 (en) 2003-11-24 2004-11-23 Method for obtaining a thermoreversible gel with a controlled three-dimensional structure, and gel obtained

Country Status (2)

Country Link
FR (1) FR2862652B1 (en)
WO (1) WO2005051428A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102012223416A1 (en) 2012-12-17 2014-07-03 Polymaterials Ag Chain extended poloxamers, thermoreversible hydrogels formed therefrom with biological materials, and medical applications thereof
WO2016090361A1 (en) * 2014-12-05 2016-06-09 Akina, Inc. (An Indiana (Us) Corp) Polymers for inducing 3d spheroid formation of biological cells
FR3078965B1 (en) 2018-03-13 2021-07-30 Safran Ceram COMPOSITE WITH CERAMIC OXIDE / OXIDE MATRIX

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6201065B1 (en) * 1995-07-28 2001-03-13 Focal, Inc. Multiblock biodegradable hydrogels for drug delivery and tissue treatment

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6201065B1 (en) * 1995-07-28 2001-03-13 Focal, Inc. Multiblock biodegradable hydrogels for drug delivery and tissue treatment

Also Published As

Publication number Publication date
FR2862652A1 (en) 2005-05-27
WO2005051428A2 (en) 2005-06-09
FR2862652B1 (en) 2006-04-28

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