WO2005055992A1 - Dispositif de dosage d'un produit destine a etre applique sur la peau - Google Patents
Dispositif de dosage d'un produit destine a etre applique sur la peau Download PDFInfo
- Publication number
- WO2005055992A1 WO2005055992A1 PCT/FR2004/003100 FR2004003100W WO2005055992A1 WO 2005055992 A1 WO2005055992 A1 WO 2005055992A1 FR 2004003100 W FR2004003100 W FR 2004003100W WO 2005055992 A1 WO2005055992 A1 WO 2005055992A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- compartments
- silkis
- amount
- approximately
- skin
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M35/00—Devices for applying media, e.g. remedies, on the human body
- A61M35/003—Portable hand-held applicators having means for dispensing or spreading integral media
-
- A—HUMAN NECESSITIES
- A45—HAND OR TRAVELLING ARTICLES
- A45D—HAIRDRESSING OR SHAVING EQUIPMENT; EQUIPMENT FOR COSMETICS OR COSMETIC TREATMENTS, e.g. FOR MANICURING OR PEDICURING
- A45D34/00—Containers or accessories specially adapted for handling liquid toiletry or cosmetic substances, e.g. perfumes
-
- A—HUMAN NECESSITIES
- A45—HAND OR TRAVELLING ARTICLES
- A45D—HAIRDRESSING OR SHAVING EQUIPMENT; EQUIPMENT FOR COSMETICS OR COSMETIC TREATMENTS, e.g. FOR MANICURING OR PEDICURING
- A45D40/00—Casings or accessories specially adapted for storing or handling solid or pasty toiletry or cosmetic substances, e.g. shaving soaps or lipsticks
- A45D40/26—Appliances specially adapted for applying pasty paint, e.g. using roller, using a ball
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
Definitions
- the present invention relates to the field of dosing of product for topical application such as a medicament.
- the invention aims to provide a new device for dosing products intended to be applied to the skin, in particular pharmaceutical or cosmetic compositions.
- the invention relates more particularly to a device in the form of a strip, the graduations of which allow users to precisely determine the quantity of medicament to be applied to the skin as a function of the surface to be treated.
- the exact dose to be delivered of said medicament cannot be calibrated by the user.
- dispensing dispensers Some are fitted with a siphon-type device which requires pumping-type manipulations by the user; they are often made up of a large number of parts, which makes them expensive to manufacture.
- Other metering distributors are equipped with a piston type device, but the quantity of product delivered being a function of the pressure exerted by the manipulator, they are unreliable.
- these dispensing dispensers are equipped with a system allowing the delivery of only a single dose of product.
- the Applicant has now developed an optimum device for dosing a medicament intended to be applied to the skin, where the quantity of medicament applied is precise and adjustable according to the surface of the skin to be treated, which allows a better effectiveness of the treatment.
- a device for dosing a product intended to be applied to the skin in particular a pharmaceutical or cosmetic composition, which is consisting of a strip comprising a longitudinal groove at which a series of compartments is defined, said groove being capable of receiving a quantity of the drug corresponding to a determined surface of the skin to be treated, this quantity being defined by one or more of the compartments .
- the slide is provided with a graduation defining from one end of the furrow corresponding to the start of the first compartment, and for the following compartments, the quantity of medicament in the compartments of the furrow.
- the device of the present invention comprises at least two, preferably at least three and most preferably four compartments.
- Said compartments may have the same dimension or be of different dimension and in the latter case, compartments of increasing size are preferred.
- dimension is preferably understood to mean the length of the compartment, but a variant of the invention consists in varying the depth or the width of the groove continuously or from one compartment to another.
- the graduation of the strip is chosen from: a graduated scale, protuberances, notches, a set of colors or a combination of these.
- the graduation of the strip can be arranged inside and / or outside the groove.
- the device comprises, preferably at at least one of the ends of the strip, a surface arranged for its manipulation. It may for example be a flared portion at one end of the strip.
- the first compartment is capable of containing an amount of the drug corresponding to approximately an area of 0.8 to 1.2% of the total surface of the body, preferably approximately 1% of the total surface of the body;
- the first and second compartments are capable of containing an amount of the drug corresponding to about an area of 2.4 to 3.6% of the total area of the body, preferably about 3% of the total area of the body; - the first, second and third compartments are capable of containing an amount of the drug corresponding to approximately an area of 4.8 to 7.1% of the total surface of the body, preferably approximately 6% of the total surface of the body ;
- the first, second, third and fourth compartments are able to contain an amount of the drug corresponding to approximately an area of 7.2 to
- the device according to the invention is remarkable in that it can be reused by the patient, that it is suitable for any form of presentation of drugs for topical application, for example liquid, semi-liquid, gels, ointments, creams, powdery.
- the device according to the invention can be made of any waterproof material meeting health requirements, such as glass, metal, flexible or rigid plastic.
- a specific application of the device according to the invention relates to the dosage of a medicament intended for treating psoriasis, said medicament preferably being Silkis.
- a medicament intended for treating psoriasis said medicament preferably being Silkis.
- the first compartment is able to contain an amount of Silkis of about 0.36 to 0.54 gram (g), preferably 0.45 gram.
- the first and second compartments are capable of containing an amount of Silkis of approximately 1.08 to 1.62 grams, preferably 1.30 grams.
- the first, second and third compartments are able to contain an amount of Silkis of approximately 2.16 to 3.20 grams, preferably 2.60 grams.
- the first, the second, the third and the fourth compartments are capable of containing an amount of Silkis of approximately 3.24 to 4.86 grams, preferably 3.90 grams.
- FIG. 1 shows an inclined top view of the metering device.
- FIG. 2 shows a top view of the metering device.
- FIG. 3 shows a side view of the metering device.
- FIG 4 shows a vertical section of the metering device.
- Figures 1, 2 and 3 show a metering device according to the invention, consisting of a strip (1) of oblong shape, provided with a graduation formed by protrusions (4).
- the strip comprises a longitudinal groove (2) provided with a series of compartments (3) and has at one end a flared circular portion (5) which facilitates the gripping of said strip.
- the strip (1) is oblong in shape 158 mm long, 32 mm wide at the end provided with the circular portion (5) and 17 mm wide at the other end .
- the groove (2) 7 mm wide and 2 mm deep extends along a longitudinal axis over 126 mm.
- This groove is divided into four compartments (3a, 3b, 3c and 3d) by protuberances (4).
- the first compartment (3a) defines a volume of 7 mm in width, 2 mm in depth and 14 mm in length.
- the second compartment (3b) defines a volume of 7 mm in width, 2 mm in depth and 28 mm in length.
- the third (3c) and the fourth (3d) compartments each define a volume of 7 mm in width, 2 mm in depth and 42 mm in length.
- Figures 3 and 4 show a metering device according to the invention, provided with a longitudinal bulge (6) on the underside of the strip (1) which constitutes the bottom of the groove (2) or a means for tilting of the device flat.
- the Applicant uses a proposition derived from the 9% rule of Wallace. The Applicant has thus determined the following percentages of body surface area (expressed relative to the total surface area of the body):
- - face 9%: 1% by ear, 1% by eyebrow, 1% chin, 1% by nasal fold, 2% forehead.
Abstract
Description
Claims
Priority Applications (8)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
BRPI0416431-8A BRPI0416431A (pt) | 2003-12-08 | 2004-12-02 | dispositivos de dosagem de um produto e de um medicamento |
CA2547673A CA2547673C (fr) | 2003-12-08 | 2004-12-02 | Dispositif de dosage d'un produit destine a etre applique sur la peau |
MXPA06006359A MXPA06006359A (es) | 2003-12-08 | 2004-12-02 | Dispositivo de dosificacion de un producto destinado a ser aplicado sobre la piel. |
AU2004296576A AU2004296576B2 (en) | 2003-12-08 | 2004-12-02 | Device for dosing a product that is intended to be applied to the skin |
KR1020067011290A KR101187232B1 (ko) | 2003-12-08 | 2004-12-02 | 피부에 사용되는 제품용 계량 장치 |
US10/582,214 US7727204B2 (en) | 2003-12-08 | 2004-12-02 | Device for dosing a product that is intended to be applied to the skin |
JP2006541978A JP2007517546A (ja) | 2003-12-08 | 2004-12-02 | 皮膚に対して適用することを意図した製品を計量するためのデバイス |
EP04805619A EP1696892A1 (fr) | 2003-12-08 | 2004-12-02 | Dispositif de dosage d'un produit destine a etre applique sur la peau |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0314335A FR2863174B1 (fr) | 2003-12-08 | 2003-12-08 | Dispositif de dosage d'un produit destine a etre applique sur la peau |
FR0314335 | 2003-12-08 |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2005055992A1 true WO2005055992A1 (fr) | 2005-06-23 |
Family
ID=34586356
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/FR2004/003100 WO2005055992A1 (fr) | 2003-12-08 | 2004-12-02 | Dispositif de dosage d'un produit destine a etre applique sur la peau |
Country Status (13)
Country | Link |
---|---|
US (1) | US7727204B2 (fr) |
EP (1) | EP1696892A1 (fr) |
JP (1) | JP2007517546A (fr) |
KR (1) | KR101187232B1 (fr) |
CN (1) | CN1889936A (fr) |
AU (1) | AU2004296576B2 (fr) |
BR (1) | BRPI0416431A (fr) |
CA (1) | CA2547673C (fr) |
FR (1) | FR2863174B1 (fr) |
MX (1) | MXPA06006359A (fr) |
RU (1) | RU2349307C2 (fr) |
WO (1) | WO2005055992A1 (fr) |
ZA (1) | ZA200605610B (fr) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20100100060A1 (en) * | 2008-10-17 | 2010-04-22 | Novartis Ag | Applicator for pharmaceutical product and method of using same |
Citations (6)
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US4486194A (en) | 1983-06-08 | 1984-12-04 | James Ferrara | Therapeutic device for administering medicaments through the skin |
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FR2593401A1 (fr) | 1985-12-17 | 1987-07-31 | Ciba Geigy Ag | Emplatres transdermiques et dermiques comportant plusieurs subdivisions |
US6315482B1 (en) | 1998-11-04 | 2001-11-13 | The Procter & Gamble Company | Applicator for applying and distributing substances to target surfaces |
EP1354591A1 (fr) * | 2002-04-17 | 2003-10-22 | MVB GmbH | Composition topique contenant des particules agglomerees de la fumee |
WO2003092784A1 (fr) | 2002-05-06 | 2003-11-13 | Vectura Limited | Dispositif d'application destine a l'administration topique d'agents pharmaceutiques |
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-
2003
- 2003-12-08 FR FR0314335A patent/FR2863174B1/fr not_active Expired - Fee Related
-
2004
- 2004-12-02 KR KR1020067011290A patent/KR101187232B1/ko not_active IP Right Cessation
- 2004-12-02 MX MXPA06006359A patent/MXPA06006359A/es active IP Right Grant
- 2004-12-02 CN CNA2004800364515A patent/CN1889936A/zh active Pending
- 2004-12-02 EP EP04805619A patent/EP1696892A1/fr not_active Withdrawn
- 2004-12-02 AU AU2004296576A patent/AU2004296576B2/en not_active Ceased
- 2004-12-02 US US10/582,214 patent/US7727204B2/en not_active Expired - Fee Related
- 2004-12-02 RU RU2006124565/15A patent/RU2349307C2/ru not_active IP Right Cessation
- 2004-12-02 WO PCT/FR2004/003100 patent/WO2005055992A1/fr active Application Filing
- 2004-12-02 BR BRPI0416431-8A patent/BRPI0416431A/pt not_active IP Right Cessation
- 2004-12-02 CA CA2547673A patent/CA2547673C/fr not_active Expired - Fee Related
- 2004-12-02 JP JP2006541978A patent/JP2007517546A/ja active Pending
-
2006
- 2006-07-07 ZA ZA200605610A patent/ZA200605610B/en unknown
Patent Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4522622A (en) * | 1982-12-23 | 1985-06-11 | Alza Corporation | Multiple fluid pulse dispenser |
US4486194A (en) | 1983-06-08 | 1984-12-04 | James Ferrara | Therapeutic device for administering medicaments through the skin |
FR2593401A1 (fr) | 1985-12-17 | 1987-07-31 | Ciba Geigy Ag | Emplatres transdermiques et dermiques comportant plusieurs subdivisions |
US6315482B1 (en) | 1998-11-04 | 2001-11-13 | The Procter & Gamble Company | Applicator for applying and distributing substances to target surfaces |
EP1354591A1 (fr) * | 2002-04-17 | 2003-10-22 | MVB GmbH | Composition topique contenant des particules agglomerees de la fumee |
WO2003092784A1 (fr) | 2002-05-06 | 2003-11-13 | Vectura Limited | Dispositif d'application destine a l'administration topique d'agents pharmaceutiques |
Non-Patent Citations (2)
Title |
---|
COMMISSION DE LA TRANSPARENCE: "SILKIS Laboratoires Galderma", 19 February 2003, XP002307502 * |
See also references of EP1696892A1 * |
Also Published As
Publication number | Publication date |
---|---|
JP2007517546A (ja) | 2007-07-05 |
KR101187232B1 (ko) | 2012-10-02 |
US7727204B2 (en) | 2010-06-01 |
AU2004296576B2 (en) | 2010-08-05 |
CA2547673C (fr) | 2013-07-02 |
ZA200605610B (en) | 2007-11-28 |
KR20060123276A (ko) | 2006-12-01 |
CN1889936A (zh) | 2007-01-03 |
FR2863174B1 (fr) | 2006-11-24 |
RU2006124565A (ru) | 2008-01-20 |
US20070191792A1 (en) | 2007-08-16 |
FR2863174A1 (fr) | 2005-06-10 |
BRPI0416431A (pt) | 2007-02-21 |
MXPA06006359A (es) | 2006-08-23 |
EP1696892A1 (fr) | 2006-09-06 |
RU2349307C2 (ru) | 2009-03-20 |
AU2004296576A1 (en) | 2005-06-23 |
CA2547673A1 (fr) | 2005-06-23 |
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