WO2005056576A3 - Branched peptide amphiphiles, related epitope compounds and self assembled structures thereof - Google Patents

Branched peptide amphiphiles, related epitope compounds and self assembled structures thereof Download PDF

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Publication number
WO2005056576A3
WO2005056576A3 PCT/US2004/040546 US2004040546W WO2005056576A3 WO 2005056576 A3 WO2005056576 A3 WO 2005056576A3 US 2004040546 W US2004040546 W US 2004040546W WO 2005056576 A3 WO2005056576 A3 WO 2005056576A3
Authority
WO
WIPO (PCT)
Prior art keywords
branched peptide
self assembled
assembled structures
related epitope
peptide amphiphiles
Prior art date
Application number
PCT/US2004/040546
Other languages
French (fr)
Other versions
WO2005056576A2 (en
Inventor
Samuel I Stupp
Mustafa O Guler
Original Assignee
Univ Northwestern
Samuel I Stupp
Mustafa O Guler
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Northwestern, Samuel I Stupp, Mustafa O Guler filed Critical Univ Northwestern
Priority to AU2004297211A priority Critical patent/AU2004297211A1/en
Priority to EP04817012A priority patent/EP1696944A4/en
Priority to MXPA06006387A priority patent/MXPA06006387A/en
Priority to JP2006542793A priority patent/JP4741510B2/en
Priority to CA002549391A priority patent/CA2549391A1/en
Publication of WO2005056576A2 publication Critical patent/WO2005056576A2/en
Publication of WO2005056576A3 publication Critical patent/WO2005056576A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0092—Hollow drug-filled fibres, tubes of the core-shell type, coated fibres, coated rods, microtubules or nanotubes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
    • A61K47/641—Branched, dendritic or hypercomb peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1019—Tetrapeptides with the first amino acid being basic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/02—Linear peptides containing at least one abnormal peptide link
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/06—Preparation of peptides or proteins produced by the hydrolysis of a peptide bond, e.g. hydrolysate products

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Epidemiology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Wood Science & Technology (AREA)
  • Nanotechnology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • General Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Branched peptide amphiphilic compounds incorporating one or residues providing a pendant amino group for coupling one or more epitope sequences thereto, such compounds and related compositions for enhanced epitope presentation.
PCT/US2004/040546 2003-12-05 2004-12-06 Branched peptide amphiphiles, related epitope compounds and self assembled structures thereof WO2005056576A2 (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
AU2004297211A AU2004297211A1 (en) 2003-12-05 2004-12-06 Branched peptide amphiphiles, related epitope compounds and self assembled structures thereof
EP04817012A EP1696944A4 (en) 2003-12-05 2004-12-06 Branched peptide amphiphiles, related epitope compounds and self assembled structures thereof
MXPA06006387A MXPA06006387A (en) 2003-12-05 2004-12-06 Branched peptide amphiphiles, related epitope compounds and self assembled structures thereof.
JP2006542793A JP4741510B2 (en) 2003-12-05 2004-12-06 Branched peptide amphiphiles, related epitope compounds and their self-assembled structures
CA002549391A CA2549391A1 (en) 2003-12-05 2004-12-06 Branched peptide amphiphiles, related epitope compounds and self assembled structures thereof

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US52744203P 2003-12-05 2003-12-05
US60/527,442 2003-12-05

Publications (2)

Publication Number Publication Date
WO2005056576A2 WO2005056576A2 (en) 2005-06-23
WO2005056576A3 true WO2005056576A3 (en) 2006-01-19

Family

ID=34676744

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2004/040546 WO2005056576A2 (en) 2003-12-05 2004-12-06 Branched peptide amphiphiles, related epitope compounds and self assembled structures thereof

Country Status (9)

Country Link
US (1) US7452679B2 (en)
EP (1) EP1696944A4 (en)
JP (1) JP4741510B2 (en)
KR (1) KR20070004561A (en)
CN (1) CN1905893A (en)
AU (1) AU2004297211A1 (en)
CA (1) CA2549391A1 (en)
MX (1) MXPA06006387A (en)
WO (1) WO2005056576A2 (en)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11087873B2 (en) 2000-05-18 2021-08-10 Carefusion 303, Inc. Context-aware healthcare notification system
US10353856B2 (en) 2011-03-17 2019-07-16 Carefusion 303, Inc. Scalable communication system
WO2003054146A2 (en) * 2001-11-14 2003-07-03 Northwestern University Self-assembly and mineralization of peptide-amphiphile nanofibers
WO2003070749A2 (en) * 2002-02-15 2003-08-28 Northwestern University Self-assembly of peptide-amphiphile nanofibers under physiological conditions
US7534761B1 (en) * 2002-08-21 2009-05-19 North Western University Charged peptide-amphiphile solutions and self-assembled peptide nanofiber networks formed therefrom
US7554021B2 (en) 2002-11-12 2009-06-30 Northwestern University Composition and method for self-assembly and mineralization of peptide amphiphiles
AU2003298647A1 (en) 2002-11-14 2004-06-15 Claussen, Randal, C. Synthesis and self-assembly of abc triblock bola peptide
WO2004072104A2 (en) * 2003-02-11 2004-08-26 Northwestern University Methods and materials for nanocrystalline surface coatings and attachment of peptide amphiphile nanofibers thereon
CN102225964A (en) * 2003-12-05 2011-10-26 西北大学 Self-assembling peptide amphiphiles and related methods for growth factor delivery
WO2005056576A2 (en) 2003-12-05 2005-06-23 Northwestern University Branched peptide amphiphiles, related epitope compounds and self assembled structures thereof
US7923109B2 (en) 2004-01-05 2011-04-12 Board Of Regents, The University Of Texas System Inorganic nanowires
MX2007008826A (en) 2005-01-21 2007-11-15 Univ Northwestern Methods and compositions for encapsulation of cells.
KR20070108555A (en) * 2005-03-04 2007-11-12 노오쓰웨스턴 유니버시티 Angiogenic heparin binding peptide amphiphiles
US20070154946A1 (en) * 2005-12-29 2007-07-05 Rajasekaran John J Massively parallel synthesis of biopolymeric arrays
US8834840B1 (en) 2006-10-04 2014-09-16 Northwestern University Magnetic resonance imaging of self-assembled biomaterial scaffolds
US7622295B2 (en) * 2006-12-19 2009-11-24 Edelmira Cabezas Molecular microarrays and helical peptides
US8772228B2 (en) * 2007-02-14 2014-07-08 Northwestern University Aligned nanofibers and related methods of use
US8076295B2 (en) * 2007-04-17 2011-12-13 Nanotope, Inc. Peptide amphiphiles having improved solubility and methods of using same
WO2009026233A2 (en) * 2007-08-17 2009-02-26 Northwestern University Self assembling peptide systems and methods
EP2217260B1 (en) * 2007-12-04 2016-11-09 Ben-Gurion University Of The Negev Research And Development Authority Amphiphilic peptide matrices for treatment of osteoporosis
US8883967B2 (en) 2009-03-27 2014-11-11 Kansas State University Research Foundation Branched amphipathic oligo-peptides that self-assemble into vesicles
KR20120012811A (en) 2009-04-13 2012-02-10 노오쓰웨스턴 유니버시티 Novel peptide-based scaffolds for cartilage regeneration and methods for their use
US20100322979A1 (en) * 2009-06-22 2010-12-23 University Of South Carolina Peptidomimetic Resorbable Peptide-Polymer Hybrid Polyester Nanoparticles
ES2659409T3 (en) 2010-03-12 2018-03-15 The Regents Of The University Of California Lipid-peptide-polymer conjugates and nanoparticles thereof
US8546338B2 (en) 2010-12-08 2013-10-01 Johnson & Johnson Consumer Companies, Inc. Self-assembling hydrogels based on dicephalic peptide amphiphiles
US9949927B2 (en) 2012-04-10 2018-04-24 The Regents Of The University Of California Bis-polymer lipid-peptide conjugates and nanoparticles thereof
US9169294B2 (en) * 2013-03-11 2015-10-27 Northwestern University Anti-angiogenic molecules, nanostructures and uses thereof
AU2014241019A1 (en) 2013-03-13 2015-09-03 Carefusion 303, Inc. Patient-specific medication management system
EP2973370A4 (en) 2013-03-13 2016-08-17 Carefusion 303 Inc Predictive medication safety
US9821278B2 (en) 2014-08-25 2017-11-21 The Governors Of The University Of Alberta Functionalized beta-sheet peptide stabilized membrane proteins, constructs comprising same, and methods of forming and using same
US20160159869A1 (en) 2014-12-09 2016-06-09 Northwestern University Bmp-2-binding peptide amphiphile nanofibers
DE102015000363A1 (en) 2015-01-20 2016-07-21 Emc Microcollections Gmbh New modular functionalizable peptide hydrogels
US11867696B2 (en) 2015-02-06 2024-01-09 Cell Idx, Inc. Antigen-coupled immunoreagents
US20170051016A1 (en) 2015-08-17 2017-02-23 Northwestern University Anti-inflammatory nanofibers
WO2017040335A2 (en) * 2015-08-28 2017-03-09 Molecular Transfer, Inc. Transfection complexes and methods of using the same
EP3362079B1 (en) 2015-10-14 2022-04-06 Northwestern University Nanofiber paste for growth factor delivery and bone regeneration
WO2018017604A1 (en) * 2016-07-18 2018-01-25 Cell Idx, Inc. Reagent compounds, compositions, kits, and methods for amplified assays
US10738294B2 (en) 2016-09-26 2020-08-11 Northwestern University Tissue factor (TF)—targeted nanotherapy
US10738338B2 (en) 2016-10-18 2020-08-11 The Research Foundation for the State University Method and composition for biocatalytic protein-oligonucleotide conjugation and protein-oligonucleotide conjugate
WO2018075885A1 (en) 2016-10-21 2018-04-26 Northwestern University Anti-microbial supramolecular structures
US11174288B2 (en) 2016-12-06 2021-11-16 Northeastern University Heparin-binding cationic peptide self-assembling peptide amphiphiles useful against drug-resistant bacteria
WO2019200326A1 (en) 2018-04-13 2019-10-17 Rarecyte, Inc. Kits for labeling of biomarkers and methods of using the same
CN110917136B (en) * 2019-11-25 2021-08-24 中国人民解放军陆军军医大学 Anti-tumor nano-emulsion adjuvant nasal mucosa vaccine and preparation method thereof
US11964000B2 (en) 2020-04-10 2024-04-23 Northwestern University Cancer treatment methods using nanofiber stabilized growth factors

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020160471A1 (en) * 2001-02-06 2002-10-31 John Kisiday Peptide scaffold encapsulation of tissue cells and uses thereof

Family Cites Families (63)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4554101A (en) * 1981-01-09 1985-11-19 New York Blood Center, Inc. Identification and preparation of epitopes on antigens and allergens on the basis of hydrophilicity
US5130123A (en) * 1981-03-04 1992-07-14 The University Of Melbourne Dentifrice
US4930077A (en) * 1987-04-06 1990-05-29 Fan David P Information processing expert system for text analysis and predicting public opinion based information available to the public
US5128319A (en) 1987-08-28 1992-07-07 Board Of Regents, The University Of Texas System Prophylaxis and therapy of acquired immunodeficiency syndrome
JPH0399096A (en) 1989-09-11 1991-04-24 Agency Of Ind Science & Technol Length control of short fiber-type helical molecule associated form
DE4026978A1 (en) * 1990-08-25 1992-02-27 Bayer Ag Coated substrates for electro=optical applications, etc.
EP0585368B1 (en) 1991-04-25 1997-08-06 Brown University Research Foundation Implantable biocompatible immunoisolatory vehicle for delivery of selected therapeutic products
WO1993022343A1 (en) 1992-05-01 1993-11-11 The Rockfeller University Multiple antigen peptide system having adjuvant properties and vaccines prepared therefrom
GB9215780D0 (en) 1992-07-24 1992-09-09 Univ London Pharmacy Peptide compounds
US5670483A (en) * 1992-12-28 1997-09-23 Massachusetts Insititute Of Technology Stable macroscopic membranes formed by self-assembly of amphiphilic peptides and uses therefor
US5955343A (en) * 1992-12-28 1999-09-21 Massachusetts Institute Of Technology Stable macroscopic membranes formed by self-assembly of amphiphilic peptides and uses therefor
US5843780A (en) * 1995-01-20 1998-12-01 Wisconsin Alumni Research Foundation Primate embryonic stem cells
US6410690B1 (en) 1995-06-07 2002-06-25 Medarex, Inc. Therapeutic compounds comprised of anti-Fc receptor antibodies
ATE342295T1 (en) * 1995-07-28 2006-11-15 Genzyme Corp BIODEGRADABLE MULTIBLOKHYDROGENS AND THEIR USE AS CARRIERS FOR CONTROLLED RELEASE PHARMACOLOGICALLY ACTIVE MATERIALS AND TISSUE CONTACT MATERIALS
FR2739860B1 (en) 1995-10-17 1998-01-02 Coletica AMPHIPHILIC COMPLEXES, PROCESS FOR THEIR PREPARATION AND COMPOSITIONS CONTAINING THE SAME
SE9504347D0 (en) 1995-12-01 1995-12-01 Boerje Sellergren Surface modification technique
US6051272A (en) * 1996-03-15 2000-04-18 The Board Of Trustees Of The University Of Illinois Method for synthesizing organoapatites on to surgical metal alloys
US5733868A (en) * 1996-04-16 1998-03-31 Depuy Orthopaedics, Inc. Poly(amino acid) adhesive tissue grafts
US6085206A (en) * 1996-06-20 2000-07-04 Microsoft Corporation Method and system for verifying accuracy of spelling and grammatical composition of a document
US5993541A (en) * 1996-07-31 1999-11-30 Geo Centers Inc Process for nucleation of ceramics and product thereof
US6096863A (en) * 1996-08-23 2000-08-01 Regents Of The University Of Minnesota Self-assembling amphiphiles for construction of peptide secondary structures
US6458924B2 (en) 1996-08-30 2002-10-01 Novo Nordisk A/S Derivatives of GLP-1 analogs
CA2278106C (en) 1997-01-22 2005-04-12 Board Of Regents, The University Of Texas System Tissue factor methods and compositions for coagulation and tumor treatment
US6331406B1 (en) * 1997-03-31 2001-12-18 The John Hopkins University School Of Medicine Human enbryonic germ cell and methods of use
US6181909B1 (en) * 1997-07-22 2001-01-30 Educational Testing Service System and method for computer-based automatic essay scoring
US6269368B1 (en) * 1997-10-17 2001-07-31 Textwise Llc Information retrieval using dynamic evidence combination
AU1615599A (en) * 1997-12-02 1999-06-16 Zen Bio, Inc. Differentiation of adipose stromal cells into osteoblasts and uses thereof
GB9801061D0 (en) 1998-01-20 1998-03-18 Univ Nottingham Patterning technique
US6548048B1 (en) 1998-04-28 2003-04-15 Amersham Health As Lipopeptide stabilized microbubbles as diagnostic/therapeutic agents
AU758178B2 (en) 1998-09-04 2003-03-20 Scios Inc. Hydrogel compositions for the controlled release administration of growth factors
CA2359318C (en) 1999-02-01 2009-06-30 Donald Elbert Biomaterials formed by nucleophilic addition reaction to conjugated unsaturated groups
WO2000045831A1 (en) 1999-02-02 2000-08-10 Thomas Jefferson University Peptides modulating activities of heparin, other glycosaminoglycans or proteoglycans
EP1159404A2 (en) 1999-03-02 2001-12-05 University of Massachusetts, a Public Institution of Higher Education of The Commonwealth of Massachusetts, Embryonic or stem-like cell lines produced by cross species nuclear transplantation
US6473730B1 (en) * 1999-04-12 2002-10-29 The Trustees Of Columbia University In The City Of New York Method and system for topical segmentation, segment significance and segment function
ES2255257T3 (en) 1999-04-22 2006-06-16 Eidgenossische Technische Hochschule (Eth) CONTROLLED RELEASE OF GROWTH FACTORS FROM MATRICES CONTAINING HEPARINE.
JP2003503071A (en) 1999-06-30 2003-01-28 アドバンスド セル テクノロジー、インコーポレイテッド Cytoplasmic transfer to dedifferentiated recipient cells
US6444723B1 (en) * 1999-11-10 2002-09-03 The United States Of America As Represented By The Secretary Of Commerce Crosslinked micellar gel composition
US6689165B2 (en) 2000-03-31 2004-02-10 Board Of Supervisors Of Louisana State University And Agricultural And Mechanical College Surface modifications for enhanced epithelialization
BR0110679A (en) 2000-04-28 2004-04-20 Univ Dublin Amphophilic macrocyclic derivatives and their analogs
AU2001261505A1 (en) * 2000-05-11 2001-11-20 University Of Southern California Machine translation techniques
JP4070605B2 (en) * 2000-10-19 2008-04-02 アイトゲノッシスシェ・テヒニッシュ・ホーホシューレ・ツューリヒ Block copolymers for multifunctional self-assembled systems
MXPA03006566A (en) * 2001-01-23 2004-10-15 Educational Testing Service Methods for automated essay analysis.
ATE419333T1 (en) 2001-02-06 2009-01-15 Massachusetts Inst Technology PEPTIDE STRUCTURE ENCAPSULATION OF TISSUE CELLS AND USES THEREOF
WO2003006043A1 (en) * 2001-07-10 2003-01-23 Massachusetts Institute Of Technology Surfactant peptide nanostructures, and uses thereof
DE20111889U1 (en) 2001-07-18 2001-10-18 Jack Wolfskin Ausruestung Fuer Belt and container equipped with such a belt
AU2002361601A1 (en) 2001-11-06 2003-05-19 Mark C. Fishman Stem and progenitor cell capture for tissue regeneration
WO2003054146A2 (en) 2001-11-14 2003-07-03 Northwestern University Self-assembly and mineralization of peptide-amphiphile nanofibers
WO2003070749A2 (en) * 2002-02-15 2003-08-28 Northwestern University Self-assembly of peptide-amphiphile nanofibers under physiological conditions
WO2003084980A2 (en) * 2002-04-02 2003-10-16 Northwestern University Peptide amphiphile solutions and self assembled peptide nanofiber networks
WO2003090255A2 (en) 2002-04-18 2003-10-30 Northwestern University Encapsulation of nanotubes via self-assembled nanostructures
WO2004003561A1 (en) 2002-06-27 2004-01-08 Northwestern University Peptide rod amphiphiles and self-assembly of same
WO2004024778A2 (en) 2002-07-23 2004-03-25 Northwestern University Self-assembled hybrid compositions and method of making, using and ordering same
US7534761B1 (en) 2002-08-21 2009-05-19 North Western University Charged peptide-amphiphile solutions and self-assembled peptide nanofiber networks formed therefrom
AU2003304152A1 (en) * 2002-09-23 2005-01-21 Northwestern University Self-assembled peptide-amphiphiles and self-assembled peptide nanofiber networks presenting multiple signals
WO2005003292A2 (en) * 2002-11-12 2005-01-13 Northwestern University Composition and method for self-assembly and mineralization of peptide amphiphiles
US7554021B2 (en) * 2002-11-12 2009-06-30 Northwestern University Composition and method for self-assembly and mineralization of peptide amphiphiles
AU2003298647A1 (en) 2002-11-14 2004-06-15 Claussen, Randal, C. Synthesis and self-assembly of abc triblock bola peptide
WO2004072104A2 (en) 2003-02-11 2004-08-26 Northwestern University Methods and materials for nanocrystalline surface coatings and attachment of peptide amphiphile nanofibers thereon
CN102225964A (en) * 2003-12-05 2011-10-26 西北大学 Self-assembling peptide amphiphiles and related methods for growth factor delivery
WO2005056576A2 (en) 2003-12-05 2005-06-23 Northwestern University Branched peptide amphiphiles, related epitope compounds and self assembled structures thereof
US20050214257A1 (en) 2003-12-23 2005-09-29 Northwestern University Compositions and methods for controlling stem cell and tumor cell differentiation, growth, and formation
MX2007008826A (en) * 2005-01-21 2007-11-15 Univ Northwestern Methods and compositions for encapsulation of cells.
KR20070108555A (en) 2005-03-04 2007-11-12 노오쓰웨스턴 유니버시티 Angiogenic heparin binding peptide amphiphiles

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020160471A1 (en) * 2001-02-06 2002-10-31 John Kisiday Peptide scaffold encapsulation of tissue cells and uses thereof

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
ANTHONY ET AL.: "Injectable Biomaterials for Bone Tissue Engineering", 2003, pages 1 - 12, XP002986075, Retrieved from the Internet <URL:http://www.nuance.northwestern.edu/downloads/Anthony%20Murphy%20Report%20Spring%202003.pdf> *
DAVID ET AL.: "The role of polar and facial amphipathic character in determining lipopolysacharide-binding properties in synthetic cationic peptides", J. ENDOTOXIN RES., vol. 6, no. 3, 2000, pages 249 - 256, XP009078240 *
DONNERS ET AL.: "Growth factor binding self-assembling nanofiber networks for tissue regeneration.", ABSTRACTS OF PAPERS, 27TH ACS NATIONAL MEETING, ANAHEIM, CA, AMERICAN CHEMICAL SOCIETY., 28 April 2004 (2004-04-28), pages BIOT-023, XP002986073 *
SHAWN ET AL.: "Self-assembling nanofiber matrix for bone regeneration.", ABSTRACTS OF PAPERS, 22TH ACS NATIONAL MEETING, ANAHEIM, CA, AMERICAN CHEMICAL SOCIETY, 28 March 2004 (2004-03-28) - 1 April 2004 (2004-04-01), pages BIOT-340, XP002986074 *
WANG ET AL.: "Epitope Identification and Discovery Using Phage Display", CURRENT DRUG TARGETS, vol. 5, no. 1, 2004, pages 1 - 15, XP009047802 *

Also Published As

Publication number Publication date
AU2004297211A1 (en) 2005-06-23
JP4741510B2 (en) 2011-08-03
US20050208589A1 (en) 2005-09-22
CN1905893A (en) 2007-01-31
EP1696944A4 (en) 2008-11-05
CA2549391A1 (en) 2005-06-23
MXPA06006387A (en) 2006-09-04
JP2007535493A (en) 2007-12-06
WO2005056576A2 (en) 2005-06-23
EP1696944A2 (en) 2006-09-06
KR20070004561A (en) 2007-01-09
US7452679B2 (en) 2008-11-18

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