WO2005077042A3 - Albumin fusion proteins - Google Patents
Albumin fusion proteins Download PDFInfo
- Publication number
- WO2005077042A3 WO2005077042A3 PCT/US2005/004041 US2005004041W WO2005077042A3 WO 2005077042 A3 WO2005077042 A3 WO 2005077042A3 US 2005004041 W US2005004041 W US 2005004041W WO 2005077042 A3 WO2005077042 A3 WO 2005077042A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- fusion proteins
- albumin fusion
- nucleic acids
- vectors
- host cells
- Prior art date
Links
- 102000009027 Albumins Human genes 0.000 title abstract 6
- 108010088751 Albumins Proteins 0.000 title abstract 6
- 102000037865 fusion proteins Human genes 0.000 title abstract 6
- 108020001507 fusion proteins Proteins 0.000 title abstract 6
- 102000039446 nucleic acids Human genes 0.000 abstract 4
- 108020004707 nucleic acids Proteins 0.000 abstract 4
- 150000007523 nucleic acids Chemical class 0.000 abstract 4
- 239000013598 vector Substances 0.000 abstract 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- 201000010099 disease Diseases 0.000 abstract 1
- 208000035475 disorder Diseases 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/76—Albumins
- C07K14/765—Serum albumin, e.g. HSA
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K19/00—Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/76—Albumins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/62—DNA sequences coding for fusion proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/31—Fusion polypeptide fusions, other than Fc, for prolonged plasma life, e.g. albumin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/35—Fusion polypeptide containing a fusion for enhanced stability/folding during expression, e.g. fusions with chaperones or thioredoxin
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Zoology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- Biophysics (AREA)
- Immunology (AREA)
- Wood Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Diabetes (AREA)
- Oncology (AREA)
- Physics & Mathematics (AREA)
- Communicable Diseases (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Transplantation (AREA)
- Virology (AREA)
- Pulmonology (AREA)
- Endocrinology (AREA)
Abstract
Priority Applications (25)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DK05722848.8T DK1729795T3 (en) | 2004-02-09 | 2005-02-09 | Albumin fusion proteins |
PL05722848T PL1729795T3 (en) | 2004-02-09 | 2005-02-09 | Albumin fusion proteins |
JP2006553197A JP5010923B2 (en) | 2004-02-09 | 2005-02-09 | Albumin fusion protein |
AU2005211725A AU2005211725B2 (en) | 2004-02-09 | 2005-02-09 | Albumin fusion proteins |
MXPA06009072A MXPA06009072A (en) | 2004-02-09 | 2005-02-09 | Albumin fusion proteins. |
EP05722848.8A EP1729795B1 (en) | 2004-02-09 | 2005-02-09 | Albumin fusion proteins |
KR1020067018484A KR101184391B1 (en) | 2004-02-09 | 2005-02-09 | Albumin fusion proteins |
CA2554089A CA2554089C (en) | 2004-02-09 | 2005-02-09 | Albumin fusion proteins |
ES05722848.8T ES2567634T3 (en) | 2004-02-09 | 2005-02-09 | Albumin Fusion Proteins |
KR1020127015659A KR101271635B1 (en) | 2001-12-21 | 2005-02-09 | Albumin fusion proteins |
SI200532048T SI1729795T1 (en) | 2004-02-09 | 2005-02-09 | Albumin fusion proteins |
BRPI0507026-0A BRPI0507026A (en) | 2004-02-09 | 2005-02-09 | albumin fusion proteins |
CN200580012252.5A CN1980687B (en) | 2004-02-09 | 2005-02-09 | Albumin fusion proteins |
NZ548612A NZ548612A (en) | 2004-02-09 | 2005-02-09 | Albumin fusion proteins comprising tandem GLP-1 |
IL176894A IL176894A (en) | 2004-02-09 | 2006-07-17 | Albumin fusion proteins comprising two or more tandemly oriented glp-1 polypeptides |
US11/495,624 US20080004206A1 (en) | 2001-12-21 | 2006-07-31 | Albumin fusion proteins |
US11/500,314 US20070048282A1 (en) | 2004-02-09 | 2006-08-08 | Albumin fusion proteins |
US11/500,508 US7569384B2 (en) | 2004-02-09 | 2006-08-08 | Albumin fusion proteins |
NO20064059A NO20064059L (en) | 2004-02-09 | 2006-09-08 | Albumin fusion proteins |
HK07101008.1A HK1095087A1 (en) | 2004-02-09 | 2007-01-29 | Albumin fusion proteins |
US11/932,823 US20080194481A1 (en) | 2001-12-21 | 2007-10-31 | Albumin Fusion Proteins |
US12/534,585 US8143026B2 (en) | 2004-02-09 | 2009-08-03 | Albumin fusion proteins |
US12/793,652 US20100291033A1 (en) | 2001-12-21 | 2010-06-03 | Albumin Fusion Proteins |
US12/793,658 US8287859B2 (en) | 2001-12-21 | 2010-06-03 | Methods of reducing toxicity and effects of cocaine by administering a butyrylcholinesterase (BChE)-albumin fusion protein |
AU2010227035A AU2010227035A1 (en) | 2004-02-09 | 2010-10-07 | Albumin fusion proteins |
Applications Claiming Priority (8)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US54227404P | 2004-02-09 | 2004-02-09 | |
US60/542,274 | 2004-02-09 | ||
US54990104P | 2004-03-05 | 2004-03-05 | |
US60/549,901 | 2004-03-05 | ||
US55690604P | 2004-03-29 | 2004-03-29 | |
US60/556,906 | 2004-03-29 | ||
US63660304P | 2004-12-17 | 2004-12-17 | |
US60/636,603 | 2004-12-17 |
Related Parent Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US12/426,882 Continuation-In-Part US20100048472A1 (en) | 2001-12-21 | 2009-04-20 | Albumin Fusion Proteins |
Related Child Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US11/495,624 Continuation-In-Part US20080004206A1 (en) | 2001-12-21 | 2006-07-31 | Albumin fusion proteins |
US11/500,508 Continuation-In-Part US7569384B2 (en) | 2001-12-21 | 2006-08-08 | Albumin fusion proteins |
US11/500,314 Continuation-In-Part US20070048282A1 (en) | 2004-02-09 | 2006-08-08 | Albumin fusion proteins |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2005077042A2 WO2005077042A2 (en) | 2005-08-25 |
WO2005077042A3 true WO2005077042A3 (en) | 2006-11-30 |
Family
ID=34865403
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2005/004041 WO2005077042A2 (en) | 2001-12-21 | 2005-02-09 | Albumin fusion proteins |
Country Status (21)
Country | Link |
---|---|
US (3) | US20070048282A1 (en) |
EP (1) | EP1729795B1 (en) |
JP (2) | JP5010923B2 (en) |
KR (1) | KR101184391B1 (en) |
CN (1) | CN102816241B (en) |
AU (2) | AU2005211725B2 (en) |
BR (1) | BRPI0507026A (en) |
CA (1) | CA2554089C (en) |
CY (1) | CY1117401T1 (en) |
DK (1) | DK1729795T3 (en) |
ES (1) | ES2567634T3 (en) |
HK (1) | HK1095087A1 (en) |
HU (1) | HUE027902T2 (en) |
IL (1) | IL176894A (en) |
MA (1) | MA28565B1 (en) |
MX (1) | MXPA06009072A (en) |
NO (1) | NO20064059L (en) |
NZ (1) | NZ548612A (en) |
PL (1) | PL1729795T3 (en) |
SI (1) | SI1729795T1 (en) |
WO (1) | WO2005077042A2 (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8993517B2 (en) | 2001-12-21 | 2015-03-31 | Human Genome Sciences, Inc. | Albumin fusion proteins |
Families Citing this family (179)
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GB9526733D0 (en) | 1995-12-30 | 1996-02-28 | Delta Biotechnology Ltd | Fusion proteins |
CA2747325A1 (en) | 2000-04-12 | 2001-10-25 | Human Genome Sciences, Inc. | Albumin fusion proteins |
US20050100991A1 (en) * | 2001-04-12 | 2005-05-12 | Human Genome Sciences, Inc. | Albumin fusion proteins |
EP1463752A4 (en) | 2001-12-21 | 2005-07-13 | Human Genome Sciences Inc | Albumin fusion proteins |
US20080194481A1 (en) | 2001-12-21 | 2008-08-14 | Human Genome Sciences, Inc. | Albumin Fusion Proteins |
US20060002935A1 (en) | 2002-06-28 | 2006-01-05 | Domantis Limited | Tumor Necrosis Factor Receptor 1 antagonists and methods of use therefor |
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