WO2005118033A3 - Needle-free injection system - Google Patents

Needle-free injection system Download PDF

Info

Publication number
WO2005118033A3
WO2005118033A3 PCT/US2005/017927 US2005017927W WO2005118033A3 WO 2005118033 A3 WO2005118033 A3 WO 2005118033A3 US 2005017927 W US2005017927 W US 2005017927W WO 2005118033 A3 WO2005118033 A3 WO 2005118033A3
Authority
WO
WIPO (PCT)
Prior art keywords
gas cartridge
gas
needle
injection
free injection
Prior art date
Application number
PCT/US2005/017927
Other languages
French (fr)
Other versions
WO2005118033A2 (en
Inventor
Sergio Landau
Ryan R Beylund
James M Bonicatto
Keith K Daellenbach
Robert A Miller
Theodore Walaka Sedler
John L Staylor
Original Assignee
Bioject Inc
Sergio Landau
Ryan R Beylund
James M Bonicatto
Keith K Daellenbach
Robert A Miller
Theodore Walaka Sedler
John L Staylor
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bioject Inc, Sergio Landau, Ryan R Beylund, James M Bonicatto, Keith K Daellenbach, Robert A Miller, Theodore Walaka Sedler, John L Staylor filed Critical Bioject Inc
Priority to EP05753221A priority Critical patent/EP1748811B1/en
Priority to CA002562250A priority patent/CA2562250A1/en
Priority to JP2007515218A priority patent/JP4633792B2/en
Priority to ES05753221T priority patent/ES2401589T3/en
Publication of WO2005118033A2 publication Critical patent/WO2005118033A2/en
Publication of WO2005118033A3 publication Critical patent/WO2005118033A3/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/30Syringes for injection by jet action, without needle, e.g. for use with replaceable ampoules or carpules
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/24Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • A61M2005/2403Ampoule inserted into the ampoule holder
    • A61M2005/2407Ampoule inserted into the ampoule holder from the rear
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/24Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • A61M2005/2485Ampoule holder connected to rest of syringe
    • A61M2005/2488Ampoule holder connected to rest of syringe via rotation, e.g. threads or bayonet
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/28Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle
    • A61M5/285Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle with sealing means to be broken or opened
    • A61M5/286Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle with sealing means to be broken or opened upon internal pressure increase, e.g. pierced or burst
    • A61M2005/287Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle with sealing means to be broken or opened upon internal pressure increase, e.g. pierced or burst by displacing occluding plugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M2005/3103Leak prevention means for distal end of syringes, i.e. syringe end for mounting a needle
    • A61M2005/3104Caps for syringes without needle
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/20Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M5/2053Media being expelled from injector by pressurised fluid or vacuum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/24Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic

Abstract

A needle-free injection device in which a gas cartridge or other source of pressurized gas is used to advance a piston and forcibly expel injectable fluid out through an injection orifice. When a gas cartridge is used, the gas cartridge may be moveable from an initial position to an actuating position in which gas is released to drive the injection, and a recoil inhibiter may be employed to prevent the gas cartridge from moving back to the initial position. A gas cartridge seal may be disposed on the gas cartridge and moveable with the gas cartridge to seal the gas cartridge against an interior wall of a gas cartridge housing. The needle-free injection device may also be configured so that sealing is compromised upon full advancement of the piston, so as to depressurize the device after delivery of an injection.
PCT/US2005/017927 2004-05-28 2005-05-20 Needle-free injection system WO2005118033A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
EP05753221A EP1748811B1 (en) 2004-05-28 2005-05-20 Needle-free injection system
CA002562250A CA2562250A1 (en) 2004-05-28 2005-05-20 Needle-free injection system
JP2007515218A JP4633792B2 (en) 2004-05-28 2005-05-20 Needleless injection system
ES05753221T ES2401589T3 (en) 2004-05-28 2005-05-20 Needleless injection system

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/857,591 2004-05-28
US10/857,591 US7717874B2 (en) 2004-05-28 2004-05-28 Needle-free injection system

Publications (2)

Publication Number Publication Date
WO2005118033A2 WO2005118033A2 (en) 2005-12-15
WO2005118033A3 true WO2005118033A3 (en) 2006-05-18

Family

ID=35426328

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2005/017927 WO2005118033A2 (en) 2004-05-28 2005-05-20 Needle-free injection system

Country Status (6)

Country Link
US (2) US7717874B2 (en)
EP (2) EP1748811B1 (en)
JP (2) JP4633792B2 (en)
CA (1) CA2562250A1 (en)
ES (1) ES2401589T3 (en)
WO (1) WO2005118033A2 (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USRE43824E1 (en) 2001-01-11 2012-11-20 Powder Pharmaceuticals Inc. Needleless syringe
US9044546B2 (en) 2007-05-04 2015-06-02 Powder Pharmaceuticals Incorporated Particle cassettes and processes therefor

Families Citing this family (84)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2414400B (en) 2004-05-28 2009-01-14 Cilag Ag Int Injection device
GB2414402B (en) 2004-05-28 2009-04-22 Cilag Ag Int Injection device
GB2414775B (en) 2004-05-28 2008-05-21 Cilag Ag Int Releasable coupling and injection device
US10737028B2 (en) 2004-11-22 2020-08-11 Kaleo, Inc. Devices, systems and methods for medicament delivery
US7648482B2 (en) 2004-11-22 2010-01-19 Intelliject, Inc. Devices, systems, and methods for medicament delivery
US7947017B2 (en) 2004-11-22 2011-05-24 Intelliject, Inc. Devices, systems and methods for medicament delivery
US11590286B2 (en) 2004-11-22 2023-02-28 Kaleo, Inc. Devices, systems and methods for medicament delivery
JP4960252B2 (en) 2004-11-22 2012-06-27 インテリジェクト,インコーポレイテッド Device, system and method for drug delivery
US7648483B2 (en) 2004-11-22 2010-01-19 Intelliject, Inc. Devices, systems and methods for medicament delivery
US8206360B2 (en) 2005-02-01 2012-06-26 Intelliject, Inc. Devices, systems and methods for medicament delivery
US7731686B2 (en) 2005-02-01 2010-06-08 Intelliject, Inc. Devices, systems and methods for medicament delivery
US9022980B2 (en) 2005-02-01 2015-05-05 Kaleo, Inc. Medical injector simulation device
ES2396745T3 (en) 2005-02-01 2013-02-25 Intelliject, Inc. Devices for medication administration
US8231573B2 (en) 2005-02-01 2012-07-31 Intelliject, Inc. Medicament delivery device having an electronic circuit system
US8361026B2 (en) 2005-02-01 2013-01-29 Intelliject, Inc. Apparatus and methods for self-administration of vaccines and other medicaments
GB2427826B (en) * 2005-04-06 2010-08-25 Cilag Ag Int Injection device comprising a locking mechanism associated with integrally formed biasing means
GB2425062B (en) 2005-04-06 2010-07-21 Cilag Ag Int Injection device
GB2424836B (en) 2005-04-06 2010-09-22 Cilag Ag Int Injection device (bayonet cap removal)
US7998134B2 (en) 2007-05-16 2011-08-16 Icu Medical, Inc. Medical connector
US20070088294A1 (en) 2005-07-06 2007-04-19 Fangrow Thomas F Jr Medical connector with closeable male luer
DE602005018480D1 (en) 2005-08-30 2010-02-04 Cilag Gmbh Int Needle device for a prefilled syringe
US20110098656A1 (en) 2005-09-27 2011-04-28 Burnell Rosie L Auto-injection device with needle protecting cap having outer and inner sleeves
GB2438593B (en) 2006-06-01 2011-03-30 Cilag Gmbh Int Injection device (cap removal feature)
GB2438591B (en) 2006-06-01 2011-07-13 Cilag Gmbh Int Injection device
GB2438590B (en) 2006-06-01 2011-02-09 Cilag Gmbh Int Injection device
US7547293B2 (en) * 2006-10-06 2009-06-16 Bioject, Inc. Triggering mechanism for needle-free injector
US20090124996A1 (en) * 2006-11-03 2009-05-14 Scott Heneveld Apparatus and methods for injecting high viscosity dermal fillers
WO2008064092A2 (en) * 2006-11-21 2008-05-29 Intelliject, Inc. Devices, systems and methods for medicament delivery
WO2008091838A2 (en) 2007-01-22 2008-07-31 Intelliject, Inc. Medical injector with compliance tracking and monitoring
WO2008103997A2 (en) 2007-02-23 2008-08-28 Bioject Inc. Needle-free injection devices and drug delivery systems therefor
WO2009086250A1 (en) * 2007-12-21 2009-07-09 Aesthetic Sciences Corporation Self-contained pressurized injection device
US8021344B2 (en) 2008-07-28 2011-09-20 Intelliject, Inc. Medicament delivery device configured to produce an audible output
USD994111S1 (en) 2008-05-12 2023-08-01 Kaleo, Inc. Medicament delivery device cover
GB2461086B (en) 2008-06-19 2012-12-05 Cilag Gmbh Int Injection device
GB2461087B (en) 2008-06-19 2012-09-26 Cilag Gmbh Int Injection device
GB2461085B (en) 2008-06-19 2012-08-29 Cilag Gmbh Int Injection device
GB2461089B (en) 2008-06-19 2012-09-19 Cilag Gmbh Int Injection device
GB2461084B (en) 2008-06-19 2012-09-26 Cilag Gmbh Int Fluid transfer assembly
US9168366B2 (en) 2008-12-19 2015-10-27 Icu Medical, Inc. Medical connector with closeable luer connector
DE102009002826A1 (en) 2009-05-05 2010-11-11 Beiersdorf Ag Needle-free injection system for delivering cosmetic active ingredients in dermis or epidermis for restructuring connective tissue, improving skin aging, reducing scar tissue and modulating sweating, comprises injector and drug formulations
DE102009033524A1 (en) * 2009-07-17 2011-01-20 Aesculap Ag Gas operated instrument
DE102010007063B4 (en) * 2010-02-06 2012-11-22 Meddrop Technology Ag Application device for atomizing a liquid
US8627816B2 (en) 2011-02-28 2014-01-14 Intelliject, Inc. Medicament delivery device for administration of opioid antagonists including formulations for naloxone
US8939943B2 (en) 2011-01-26 2015-01-27 Kaleo, Inc. Medicament delivery device for administration of opioid antagonists including formulations for naloxone
US9084849B2 (en) 2011-01-26 2015-07-21 Kaleo, Inc. Medicament delivery devices for administration of a medicament within a prefilled syringe
EP2753396B1 (en) 2011-09-09 2017-12-27 ICU Medical, Inc. Medical connectors with fluid-resistant mating interfaces
CA3029492C (en) 2011-12-15 2019-09-10 Socpra Sciences Et Genie S.E.C. Mechanism for puncturing a gas cartridge
US9522235B2 (en) 2012-05-22 2016-12-20 Kaleo, Inc. Devices and methods for delivering medicaments from a multi-chamber container
RU2649460C2 (en) * 2012-06-04 2018-04-03 Алькон Фармасьютикалз, Лтд. Intraocular lens insertion device
CN104619285B (en) 2012-06-12 2018-05-01 奥特威资有限责任公司 Intraocular gas syringe
PL2732770T3 (en) * 2012-11-16 2016-12-30 Needle-free injection device
WO2014106096A1 (en) 2012-12-27 2014-07-03 Kaleo, Inc. Devices, systems and methods for locating and interacting with medicament delivery systems
GB2515039B (en) 2013-06-11 2015-05-27 Cilag Gmbh Int Injection Device
GB2515038A (en) 2013-06-11 2014-12-17 Cilag Gmbh Int Injection device
GB2517896B (en) 2013-06-11 2015-07-08 Cilag Gmbh Int Injection device
GB2515032A (en) 2013-06-11 2014-12-17 Cilag Gmbh Int Guide for an injection device
CN103550848B (en) * 2013-11-18 2015-06-03 江西三鑫医疗科技股份有限公司 Needle-free syringe
CA2943721C (en) 2014-03-26 2021-06-08 L.O.M. Laboratories Inc. Gas release cell
WO2015154049A1 (en) * 2014-04-04 2015-10-08 Altaviz, Llc Intraocular lens inserter
RU2695562C2 (en) 2014-07-15 2019-07-24 Алькон Фармасьютикалз, Лтд. Device for insertion of intraocular lens with temperature compensation
US9517307B2 (en) 2014-07-18 2016-12-13 Kaleo, Inc. Devices and methods for delivering opioid antagonists including formulations for naloxone
US10588780B2 (en) 2015-03-04 2020-03-17 Alcon Inc. Intraocular lens injector
BR112017020163B1 (en) * 2015-03-23 2022-09-06 Sanofi-Aventis Deutschland Gmbh ACCOMMODATION FOR AN INJECTION DEVICE AND INJECTION DEVICE
US10695495B2 (en) 2015-03-24 2020-06-30 Kaleo, Inc. Devices and methods for delivering a lyophilized medicament
WO2017004345A1 (en) 2015-06-30 2017-01-05 Kaleo, Inc. Auto-injectors for administration of a medicament within a prefilled syringe
US10172706B2 (en) 2015-10-31 2019-01-08 Novartis Ag Intraocular lens inserter
WO2017151197A1 (en) * 2015-11-24 2017-09-08 Aktivax, Inc. Pressure cartridge and activation mechanism
WO2017089280A1 (en) * 2015-11-27 2017-06-01 Sanofi-Aventis Deutschland Gmbh Injection apparatus
EP3184074A1 (en) 2015-12-23 2017-06-28 Sulzer Mixpac AG Discharger
JP7014797B2 (en) 2016-12-23 2022-02-01 カレオ,インコーポレイテッド Drug delivery devices and methods for delivering drugs to babies and children
US11000367B2 (en) 2017-01-13 2021-05-11 Alcon Inc. Intraocular lens injector
US10568735B2 (en) 2017-01-13 2020-02-25 Alcon Inc. Intraocular lens injector
WO2018136413A2 (en) 2017-01-17 2018-07-26 Kaleo, Inc. Medicament delivery devices with wireless connectivity and event detection
KR20200085284A (en) * 2017-11-04 2020-07-14 알타비즈 엘엘씨 Gas driven fluid injection system
CN111417423B (en) * 2017-11-04 2022-10-11 奥特威资有限责任公司 Injection device and methods of making and using the same
US11890453B2 (en) * 2017-11-04 2024-02-06 Altaviz, Llc Injection devices and methods for making and using them
EP3706831A4 (en) 2017-11-09 2021-08-11 Aijex Pharma International Inc. Needleless injector assemblies and related methods
WO2020018433A1 (en) 2018-07-16 2020-01-23 Kaleo, Inc. Medicament delivery devices with wireless connectivity and compliance detection
KR102507797B1 (en) * 2018-09-22 2023-03-09 에스에이치엘 메디컬 아게 pneumatic power pack
US11224537B2 (en) 2018-10-19 2022-01-18 Alcon Inc. Intraocular gas injector
EP4009936A4 (en) 2019-08-09 2023-08-09 Kaleo, Inc. Devices and methods for delivery of substances within a prefilled syringe
KR102611990B1 (en) * 2021-02-19 2023-12-11 (주)바이오시드 One touch type of semi-automatic needle-less injector using gas pressure
WO2023173142A2 (en) * 2022-03-11 2023-09-14 Aktivax, Inc. Dispensing device incorporating a diaphragm
CN115429974B (en) * 2022-09-07 2023-09-15 北京快舒尔医疗技术有限公司 Needleless injector

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3688765A (en) * 1969-10-03 1972-09-05 Jack S Gasaway Hypodermic injection device
US3802430A (en) * 1972-06-30 1974-04-09 L Arnold Disposable pyrotechnically powered injector
US5064413A (en) * 1989-11-09 1991-11-12 Bioject, Inc. Needleless hypodermic injection device

Family Cites Families (95)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2545017A (en) 1947-06-02 1951-03-13 Gordon D Billingsley Hypodermic syringe
US2680439A (en) 1948-09-08 1954-06-08 Arnold K Sutermeister High-pressure injection device
US2653602A (en) 1950-06-17 1953-09-29 Becton Dickinson Co Injection device
US2667874A (en) 1951-07-09 1954-02-02 Becton Dickinson Co Medicament cartridge assembly
US3110309A (en) 1960-08-15 1963-11-12 Brunswick Corp Plastic cartridge needle assembly
US3115133A (en) 1962-05-15 1963-12-24 Morando Emilio Donald Needleless prefilled disposable hypodermic injector
US3202151A (en) 1963-04-08 1965-08-24 Scherer Corp R P Multidose jet injector
US3292621A (en) 1963-07-19 1966-12-20 Oscar H Banker Jet type protable inoculator
US3507276A (en) 1968-08-28 1970-04-21 Murray B Burgess Jet injector
US3561443A (en) 1968-09-06 1971-02-09 Oscar H Banker Inoculator gun with delayed action
US3695266A (en) 1970-06-18 1972-10-03 Maurice G Lussier Needleless sequential dosing syringe
US3941128A (en) 1970-11-10 1976-03-02 Affiliated Hospital Products, Inc. Fluid dispensing arrangement
US3714943A (en) 1970-12-01 1973-02-06 H Yanof Medicament injectors
US3853125A (en) 1971-10-05 1974-12-10 W Clark Disposable needleless injector
US3729031A (en) 1971-12-06 1973-04-24 Mpl Inc Liquid dispenser and plunger and method and apparatus for filling same
US3859996A (en) 1973-07-18 1975-01-14 Mizzy Inc Multi-dose injector
US3940003A (en) 1974-05-07 1976-02-24 Pharmaco, Inc. Safety cap for medicament vial having puncturable seal
US3945379A (en) 1974-08-08 1976-03-23 Smithkline Corporation Injection device
JPS51130094A (en) 1975-05-08 1976-11-12 Asahi Chemical Ind Twoostage pressure injector
US4124024A (en) 1977-03-03 1978-11-07 Schwebel Paul R Disposable hypodermic injection ampule
BR7806153A (en) 1978-09-19 1980-04-01 Halen Elliot Brasil Ind Com Eq HYPODERMIC PRESSURE INJECTOR FOR INTERMITTENT VACCINATION
US4479801A (en) 1982-06-25 1984-10-30 Cohen Milton J Fluid dispensing device
US4592745A (en) 1984-02-29 1986-06-03 Novo Industri A/S Dispenser
US4652261A (en) 1984-06-22 1987-03-24 Regents Of The University Of Minnesota Drug-injection animal capture collar
US4596556A (en) 1985-03-25 1986-06-24 Bioject, Inc. Hypodermic injection apparatus
US4662878A (en) 1985-11-13 1987-05-05 Patents Unlimited Ltd. Medicine vial adaptor for needleless injector
US4680027A (en) 1985-12-12 1987-07-14 Injet Medical Products, Inc. Needleless hypodermic injection device
EP0250022A3 (en) 1986-06-17 1988-06-22 SICIM SpA Portable endermic injector
US4713061A (en) 1986-07-14 1987-12-15 Survival Technology, Inc. Cartridge with universal plastic hub
US4747839A (en) 1986-12-17 1988-05-31 Survival Technology, Inc. Disposable hypodermic syringe with plastic snap-on needle hub and heat shrink seal therefor
US4717384A (en) 1987-01-15 1988-01-05 Pneu Dart Inc. Pneumatic hypodermic syringe pole
US4886495A (en) 1987-07-08 1989-12-12 Duoject Medical Systems Inc. Vial-based prefilled syringe system for one or two component medicaments
US5569190A (en) 1987-06-08 1996-10-29 D'antonio; Nicholas F. Hypodermic fluid dispenser
US6056716A (en) 1987-06-08 2000-05-02 D'antonio Consultants International Inc. Hypodermic fluid dispenser
US5080648A (en) 1987-06-08 1992-01-14 Antonio Nicholas F D Hypodermic fluid dispenser
US4790824A (en) 1987-06-19 1988-12-13 Bioject, Inc. Non-invasive hypodermic injection device
US4941880A (en) 1987-06-19 1990-07-17 Bioject, Inc. Pre-filled ampule and non-invasive hypodermic injection device assembly
US4940460A (en) 1987-06-19 1990-07-10 Bioject, Inc. Patient-fillable and non-invasive hypodermic injection device assembly
AU628029B2 (en) 1987-11-16 1992-09-10 Sy-Quest International Limited Improved apparatus for hypodermic injection of liquids
AU595096B2 (en) 1988-02-10 1990-03-22 Astra Pharmaceuticals Pty Ltd Plastic cartridge and syringe
US4913699A (en) 1988-03-14 1990-04-03 Parsons James S Disposable needleless injection system
US4909794A (en) 1988-06-24 1990-03-20 Habley Medical Technology Corporation Combination retractable needle cannula and cannula lock for a medication carpule
US5024656A (en) 1988-08-30 1991-06-18 Injet Medical Products, Inc. Gas-pressure-regulated needleless injection system
US5312335A (en) 1989-11-09 1994-05-17 Bioject Inc. Needleless hypodermic injection device
AU6550990A (en) 1989-11-09 1991-05-16 Bioject, Inc. Needleless hypodermic injection device
US5049128A (en) 1990-02-06 1991-09-17 Duquette Irene A Valved infusion port
EP0518416A1 (en) 1991-06-13 1992-12-16 Duphar International Research B.V Injection device
DK134691D0 (en) 1991-07-12 1991-07-12 Novo Nordisk As APPARATUS
US6902555B2 (en) 1991-07-15 2005-06-07 Larry D. Paskar Shapeable catheter
GB9212742D0 (en) 1992-06-16 1992-07-29 Sterimatic Holdings Ltd Syringe or blood collection system
US5383851A (en) 1992-07-24 1995-01-24 Bioject Inc. Needleless hypodermic injection device
WO1994007554A1 (en) 1992-09-28 1994-04-14 Equidyne Systems, Incorporated Hypodermic jet injector
US5569189A (en) 1992-09-28 1996-10-29 Equidyne Systems, Inc. hypodermic jet injector
US5334144A (en) 1992-10-30 1994-08-02 Becton, Dickinson And Company Single use disposable needleless injector
US5380295A (en) * 1992-12-14 1995-01-10 Mallinckrodt Medical, Inc. Delivery apparatus with mechanism preventing rearward movement of a piston disposed therein
US5405333A (en) 1992-12-28 1995-04-11 Richmond; Frank M. Liquid medicament bag with needleless connector fitting using boat assembly
TW404844B (en) 1993-04-08 2000-09-11 Oxford Biosciences Ltd Needleless syringe
US5364386A (en) 1993-05-05 1994-11-15 Hikari Seiyaku Kabushiki Kaisha Infusion unit
US5453096A (en) 1993-07-26 1995-09-26 Merck & Co., Inc. Device for the distribution of successive doses of a fluid product-in particular medicinal or cosmetic-contained in a vial
US5472022A (en) 1993-11-02 1995-12-05 Genentech, Inc. Injection pen solution transfer apparatus and method
US5599302A (en) 1995-01-09 1997-02-04 Medi-Ject Corporation Medical injection system and method, gas spring thereof and launching device using gas spring
US5730723A (en) 1995-10-10 1998-03-24 Visionary Medical Products Corporation, Inc. Gas pressured needle-less injection device and method
FR2739562B1 (en) 1995-10-09 1998-04-24 Moreau Defarges Alain JET INJECTION DEVICE WITHOUT NEEDLE, INCLUDING AN OVER-MOLDED CARTRIDGE
US6080130A (en) 1998-11-14 2000-06-27 Castellano; Thomas P. Gas power source for a needle-less injector
US5716348A (en) 1995-10-19 1998-02-10 Meridian Medical Technologies, Inc. Anti-coring needle
US5921967A (en) 1996-02-29 1999-07-13 Medi-Ject Corporation Plunger for nozzle assembly
US5865795A (en) 1996-02-29 1999-02-02 Medi-Ject Corporation Safety mechanism for injection devices
US5769138A (en) 1996-04-01 1998-06-23 Medi-Ject Corporation Nozzle and adapter for loading medicament into an injector
GB9607549D0 (en) 1996-04-11 1996-06-12 Weston Medical Ltd Spring-powered dispensing device
SE9604162D0 (en) 1996-11-13 1996-11-13 Astra Ab membrane
EP0957980A4 (en) 1996-11-27 2000-03-29 Gen Hospital Corp Compound delivery using impulse transients
US5938637A (en) 1997-03-14 1999-08-17 Path Single-use medicine delivery unit for needleless hypodermic injector
US5993412A (en) 1997-05-19 1999-11-30 Bioject, Inc. Injection apparatus
US5911703A (en) 1997-05-22 1999-06-15 Avant Drug Delivery Systems, Inc. Two-stage fluid medicament jet injector
EP0888790A1 (en) 1997-07-04 1999-01-07 PowderJect Research Limited Drug particle delivery device
US6156008A (en) 1998-05-04 2000-12-05 Castellano; Thomas P. Device for avoiding subdermal hematomas from an injection
US6264629B1 (en) * 1998-11-18 2001-07-24 Bioject, Inc. Single-use needle-less hypodermic jet injection apparatus and method
US6689093B2 (en) 1998-11-18 2004-02-10 Bioject, Inc. Single-use needle-less hypodermic jet injection apparatus and method
US6096002A (en) 1998-11-18 2000-08-01 Bioject, Inc. NGAS powered self-resetting needle-less hypodermic jet injection apparatus and method
US6383168B1 (en) 1998-12-08 2002-05-07 Bioject Medical Technologies Inc. Needleless syringe with prefilled cartridge
US6132395A (en) 1998-12-08 2000-10-17 Bioject, Inc. Needleless syringe with prefilled cartridge
US6406455B1 (en) 1998-12-18 2002-06-18 Biovalve Technologies, Inc. Injection devices
WO2001013975A2 (en) 1999-08-20 2001-03-01 Bioject, Inc. Dna-based intramuscular injection system for humans
US6224567B1 (en) 1999-09-08 2001-05-01 Cambridge Biostability Limited Modified disposable injector device
US7887506B1 (en) 1999-11-23 2011-02-15 Pulse Needlefree Systems, Inc. Safety mechanism to prevent accidental patient injection and methods of same
US6210359B1 (en) 2000-01-21 2001-04-03 Jet Medica, L.L.C. Needleless syringe
CA2331030A1 (en) * 2000-02-16 2001-08-16 Roche Diagnostics Gmbh Hypodermic needleless injection system
US6558348B2 (en) 2000-04-07 2003-05-06 Equidyne Systems, Inc. Low cost disposable needleless injector system for variable and fixed dose applications
US6716190B1 (en) 2000-04-19 2004-04-06 Scimed Life Systems, Inc. Device and methods for the delivery and injection of therapeutic and diagnostic agents to a target site within a body
EP1170828B1 (en) * 2000-07-06 2012-01-11 Yazaki Corporation Protective cover
US6471669B2 (en) 2001-03-05 2002-10-29 Bioject Medical Technologies Inc. Disposable needle-free injection apparatus and method
WO2003030756A2 (en) 2001-10-12 2003-04-17 Ams Research Corporation Surgical instrument and method
US6607510B2 (en) * 2001-11-09 2003-08-19 Bioject Medical Technologies Inc. Disposable needle-free injection apparatus and method
US6676630B2 (en) 2002-06-04 2004-01-13 Bioject Medical Technologies, Inc. Needle-free injection system
US7156823B2 (en) 2002-06-04 2007-01-02 Bioject Inc. High workload needle-free injection system

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3688765A (en) * 1969-10-03 1972-09-05 Jack S Gasaway Hypodermic injection device
US3802430A (en) * 1972-06-30 1974-04-09 L Arnold Disposable pyrotechnically powered injector
US5064413A (en) * 1989-11-09 1991-11-12 Bioject, Inc. Needleless hypodermic injection device

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USRE43824E1 (en) 2001-01-11 2012-11-20 Powder Pharmaceuticals Inc. Needleless syringe
US9044546B2 (en) 2007-05-04 2015-06-02 Powder Pharmaceuticals Incorporated Particle cassettes and processes therefor
US9358338B2 (en) 2007-05-04 2016-06-07 Powder Pharmaceuticals Incorporated Particle cassettes and processes therefor

Also Published As

Publication number Publication date
EP2386325A3 (en) 2012-08-08
CA2562250A1 (en) 2005-12-15
EP1748811A2 (en) 2007-02-07
JP2010279706A (en) 2010-12-16
ES2401589T3 (en) 2013-04-22
US20100069831A1 (en) 2010-03-18
US7717874B2 (en) 2010-05-18
EP2386325A2 (en) 2011-11-16
US7854720B2 (en) 2010-12-21
JP5171893B2 (en) 2013-03-27
EP1748811A4 (en) 2009-04-08
JP2008500876A (en) 2008-01-17
JP4633792B2 (en) 2011-02-16
WO2005118033A2 (en) 2005-12-15
EP1748811B1 (en) 2012-12-19
US20050267403A1 (en) 2005-12-01

Similar Documents

Publication Publication Date Title
WO2005118033A3 (en) Needle-free injection system
AU2003202340A1 (en) Needleless injector
UA94121C2 (en) Injection device and method of operating an injection device
ATE516855T1 (en) FIRE EXTINGUISHING DEVICE WITH EXTINGUISHING AGENT CONTAINER
WO2005122722A3 (en) Hypodermic injection system
DE50111473D1 (en) Needle-free injection device with pyrotechnic drive
GB2414405B (en) Injection device
WO2008042701A3 (en) Syringe with selectable indicia of contents
TW200702008A (en) Needle-less injector
WO2010054085A3 (en) Multiple component mixing and delivery system
DE60219505D1 (en) NEEDLESS ONE-WAY INJECTION DEVICE
GB2455667A (en) Gas activated actuator device for downhole tools
WO2008005315A8 (en) Automatic injection device
AR057478A1 (en) Ophthalmic Injector System
MX2018015896A (en) Prepackaged bug gun magazine.
WO2006047087A3 (en) Spring powered needle-free injection system
NO20072905L (en) Throttle valve for fluid injection in geological formations.
DE50212880D1 (en)
WO2006073394A8 (en) Needle-free injection system
KR101509314B1 (en) self-protection gun
SG140491A1 (en) An injection device
MY152499A (en) Syringe

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BW BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE EG ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KM KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NA NG NI NO NZ OM PG PH PL PT RO RU SC SD SE SG SK SL SM SY TJ TM TN TR TT TZ UA UG US UZ VC VN YU ZA ZM ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): BW GH GM KE LS MW MZ NA SD SL SZ TZ UG ZM ZW AM AZ BY KG KZ MD RU TJ TM AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LT LU MC NL PL PT RO SE SI SK TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
WWE Wipo information: entry into national phase

Ref document number: 2005753221

Country of ref document: EP

WWE Wipo information: entry into national phase

Ref document number: 2562250

Country of ref document: CA

WWE Wipo information: entry into national phase

Ref document number: 2007515218

Country of ref document: JP

NENP Non-entry into the national phase

Ref country code: DE

WWW Wipo information: withdrawn in national office

Country of ref document: DE

WWP Wipo information: published in national office

Ref document number: 2005753221

Country of ref document: EP