WO2006002399A3 - Biodegradable implantable medical devices, methods and systems - Google Patents

Biodegradable implantable medical devices, methods and systems Download PDF

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Publication number
WO2006002399A3
WO2006002399A3 PCT/US2005/022582 US2005022582W WO2006002399A3 WO 2006002399 A3 WO2006002399 A3 WO 2006002399A3 US 2005022582 W US2005022582 W US 2005022582W WO 2006002399 A3 WO2006002399 A3 WO 2006002399A3
Authority
WO
WIPO (PCT)
Prior art keywords
medical devices
methods
systems
implantable medical
biodegradable implantable
Prior art date
Application number
PCT/US2005/022582
Other languages
French (fr)
Other versions
WO2006002399A2 (en
Inventor
Patrick E Guire
Kristin S Taton
Jie Wen
Witt David M De
Bob Hergenrother
Aron B Anderson
Original Assignee
Surmodics Inc
Patrick E Guire
Kristin S Taton
Jie Wen
Witt David M De
Bob Hergenrother
Aron B Anderson
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Surmodics Inc, Patrick E Guire, Kristin S Taton, Jie Wen, Witt David M De, Bob Hergenrother, Aron B Anderson filed Critical Surmodics Inc
Publication of WO2006002399A2 publication Critical patent/WO2006002399A2/en
Publication of WO2006002399A3 publication Critical patent/WO2006002399A3/en

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/04Macromolecular materials
    • A61L31/06Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/148Materials at least partially resorbable by the body

Abstract

The invention provides implantable intraluminal medical devices that are fabricated of biodegradable materials. The invention further provides methods of treatment utilizing the devices.
PCT/US2005/022582 2004-06-24 2005-06-24 Biodegradable implantable medical devices, methods and systems WO2006002399A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US58317104P 2004-06-24 2004-06-24
US60/583,171 2004-06-24

Publications (2)

Publication Number Publication Date
WO2006002399A2 WO2006002399A2 (en) 2006-01-05
WO2006002399A3 true WO2006002399A3 (en) 2006-03-16

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2005/022582 WO2006002399A2 (en) 2004-06-24 2005-06-24 Biodegradable implantable medical devices, methods and systems

Country Status (2)

Country Link
US (1) US20060018948A1 (en)
WO (1) WO2006002399A2 (en)

Families Citing this family (107)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7611533B2 (en) * 1995-06-07 2009-11-03 Cook Incorporated Coated implantable medical device
US6607751B1 (en) * 1997-10-10 2003-08-19 Intellipharamaceutics Corp. Controlled release delivery device for pharmaceutical agents incorporating microbial polysaccharide gum
CA2529984C (en) 2003-06-26 2012-09-25 Isa Odidi Oral multi-functional pharmaceutical capsule preparations of proton pump inhibitors
US20060246109A1 (en) * 2005-04-29 2006-11-02 Hossainy Syed F Concentration gradient profiles for control of agent release rates from polymer matrices
US20060024361A1 (en) * 2004-07-28 2006-02-02 Isa Odidi Disintegrant assisted controlled release technology
EP2594259A1 (en) 2004-08-04 2013-05-22 Brookwood Pharmaceuticals, Inc. Methods for manufacturing delivery devices and devices thereof
US20060034891A1 (en) * 2004-08-12 2006-02-16 Laurie Lawin Biodegradable controlled release bioactive agent delivery device
US10624858B2 (en) * 2004-08-23 2020-04-21 Intellipharmaceutics Corp Controlled release composition using transition coating, and method of preparing same
US8083805B2 (en) * 2005-08-16 2011-12-27 Poly-Med, Inc. Absorbable endo-urological devices and applications therefor
EP1853259A1 (en) 2005-02-09 2007-11-14 Macusight, Inc. Formulations for ocular treatment
US8663639B2 (en) 2005-02-09 2014-03-04 Santen Pharmaceutical Co., Ltd. Formulations for treating ocular diseases and conditions
US7785291B2 (en) * 2005-03-01 2010-08-31 Tulip Medical Ltd. Bioerodible self-deployable intragastric implants
US7699863B2 (en) * 2005-03-01 2010-04-20 Tulip Medical Ltd. Bioerodible self-deployable intragastric implants
US20070269486A1 (en) * 2005-03-14 2007-11-22 Conor Medsystems, Llc. Methods and Devices for Reducing Tissue Damage After Ischemic Injury
US20070038290A1 (en) * 2005-08-15 2007-02-15 Bin Huang Fiber reinforced composite stents
US9248034B2 (en) 2005-08-23 2016-02-02 Advanced Cardiovascular Systems, Inc. Controlled disintegrating implantable medical devices
US20090053391A1 (en) * 2005-12-06 2009-02-26 Ludwig Florian N Method Of Coating A Drug-Releasing Layer Onto A Substrate
US20070128246A1 (en) * 2005-12-06 2007-06-07 Hossainy Syed F A Solventless method for forming a coating
US20070148251A1 (en) * 2005-12-22 2007-06-28 Hossainy Syed F A Nanoparticle releasing medical devices
US10064828B1 (en) 2005-12-23 2018-09-04 Intellipharmaceutics Corp. Pulsed extended-pulsed and extended-pulsed pulsed drug delivery systems
AU2007212025A1 (en) * 2006-02-06 2007-08-16 Conor Medsystems, Inc. Drug delivery stent with extended in vivo drug release
US9592325B2 (en) * 2006-02-07 2017-03-14 Tepha, Inc. Polymeric, degradable drug-eluting stents and coatings
US8979921B2 (en) * 2006-02-07 2015-03-17 Tepha, Inc. Polymeric, degradable drug-eluting stents and coatings
ES2395076T3 (en) * 2006-02-07 2013-02-08 Tepha, Inc. Drug-releasing polymer degradable stents and coatings
WO2007092620A2 (en) 2006-02-09 2007-08-16 Macusight, Inc. Stable formulations, and methods of their preparation and use
US20070225544A1 (en) * 2006-02-17 2007-09-27 Vance Waseet Apparatuses and techniques for bioactive drug delivery in the prostate gland
AU2007230964B2 (en) 2006-03-23 2012-07-19 Santen Pharmaceutical Co., Ltd. Formulations and methods for vascular permeability-related diseases or conditions
US20080051335A1 (en) * 2006-05-02 2008-02-28 Kleiner Lothar W Methods, compositions and devices for treating lesioned sites using bioabsorbable carriers
US8221468B2 (en) 2006-05-11 2012-07-17 Gaines Jr Robert W Use of bioabsorbable materials for anterior extradiscal correction of thoracolumbar pathologies
US10960077B2 (en) 2006-05-12 2021-03-30 Intellipharmaceutics Corp. Abuse and alcohol resistant drug composition
US7818084B2 (en) * 2006-06-16 2010-10-19 The Invention Science Fund, I, LLC Methods and systems for making a blood vessel sleeve
US8246973B2 (en) 2006-06-21 2012-08-21 Advanced Cardiovascular Systems, Inc. Freeze-thaw method for modifying stent coating
US9173733B1 (en) * 2006-08-21 2015-11-03 Abbott Cardiovascular Systems Inc. Tracheobronchial implantable medical device and methods of use
US20090169628A1 (en) * 2006-10-17 2009-07-02 Armark Authentication Technologies, Llc Article and method for focused delivery of therapeutic and/or diagnostic materials
US20100166854A1 (en) * 2006-10-30 2010-07-01 Rutgers, The State University Of New Jersey Electrospun matrices for delivery of hydrophilic and lipophilic compounds
US20090263346A1 (en) * 2006-12-05 2009-10-22 David Taft Systems and methods for delivery of drugs
US20090246155A1 (en) * 2006-12-05 2009-10-01 Landec Corporation Compositions and methods for personal care
EP2500015A1 (en) * 2006-12-05 2012-09-19 Landec Corporation Delivery of drugs
US8399007B2 (en) * 2006-12-05 2013-03-19 Landec Corporation Method for formulating a controlled-release pharmaceutical formulation
US20100004124A1 (en) * 2006-12-05 2010-01-07 David Taft Systems and methods for delivery of materials for agriculture and aquaculture
US8133553B2 (en) 2007-06-18 2012-03-13 Zimmer, Inc. Process for forming a ceramic layer
US8309521B2 (en) 2007-06-19 2012-11-13 Zimmer, Inc. Spacer with a coating thereon for use with an implant device
US20110230973A1 (en) * 2007-10-10 2011-09-22 Zimmer, Inc. Method for bonding a tantalum structure to a cobalt-alloy substrate
US8608049B2 (en) * 2007-10-10 2013-12-17 Zimmer, Inc. Method for bonding a tantalum structure to a cobalt-alloy substrate
US8124601B2 (en) * 2007-11-21 2012-02-28 Bristol-Myers Squibb Company Compounds for the treatment of Hepatitis C
WO2009070794A1 (en) * 2007-11-29 2009-06-04 Jackson Gregg A Progesterone-containing compositions and devices
US8114883B2 (en) * 2007-12-04 2012-02-14 Landec Corporation Polymer formulations for delivery of bioactive materials
CA2709712C (en) 2007-12-20 2016-05-10 Surmodics Pharmaceuticals, Inc. Process for preparing microparticles having a low residual solvent volume
US20090188521A1 (en) * 2008-01-17 2009-07-30 Evazynajad Ali M Dental Floss Formed from Botanic and Botanically Derived Fiber
US20090187256A1 (en) * 2008-01-21 2009-07-23 Zimmer, Inc. Method for forming an integral porous region in a cast implant
CA2719222C (en) 2008-03-28 2018-07-24 Surmodics, Inc. Insertable medical devices having microparticulate-associated elastic substrates and methods for drug delivery
US8034396B2 (en) * 2008-04-01 2011-10-11 Tyco Healthcare Group Lp Bioadhesive composition formed using click chemistry
EP2293838B1 (en) 2008-07-01 2012-08-08 Endologix, Inc. Catheter system
US8557288B2 (en) * 2008-08-15 2013-10-15 Washington University Hydrogel microparticle formation in aqueous solvent for biomedical applications
CA2734410A1 (en) * 2008-09-05 2010-03-11 Innovative Surface Technologies, Inc. Photoactivatable crosslinker compositions for surface modification
WO2010045674A1 (en) * 2008-10-22 2010-04-29 Novogen Research Pty Ltd Methods for inducing programmed cell death
EP2398523B1 (en) 2009-02-21 2018-04-04 Covidien LP Medical devices having activated surfaces
US8535477B2 (en) 2009-02-21 2013-09-17 Sofradim Production Medical devices incorporating functional adhesives
US8663689B2 (en) * 2009-02-21 2014-03-04 Sofradim Production Functionalized adhesive medical gel
US9039979B2 (en) 2009-02-21 2015-05-26 Sofradim Production Apparatus and method of reacting polymers passing through metal ion chelated resin matrix to produce injectable medical devices
AU2010215203B2 (en) 2009-02-21 2015-07-16 Covidien Lp Medical devices with an activated coating
WO2010095049A1 (en) 2009-02-21 2010-08-26 Sofradim Production Crosslinked fibers and method of making same by extrusion
US8969473B2 (en) 2009-02-21 2015-03-03 Sofradim Production Compounds and medical devices activated with solvophobic linkers
ES2415161T3 (en) * 2009-02-21 2013-07-24 Sofradim Production Medical device and manufacturing procedure
CA2753162A1 (en) 2009-02-21 2010-08-26 Sofradim Production Amphiphilic compounds and self-assembling compositions made therefrom
US8512728B2 (en) 2009-02-21 2013-08-20 Sofradim Production Method of forming a medical device on biological tissue
US8968818B2 (en) 2009-02-21 2015-03-03 Covidien Lp Medical devices having activated surfaces
US8877170B2 (en) * 2009-02-21 2014-11-04 Sofradim Production Medical device with inflammatory response-reducing coating
US8968733B2 (en) * 2009-02-21 2015-03-03 Sofradim Production Functionalized surgical adhesives
AU2010215200A1 (en) 2009-02-21 2011-10-13 Sofradim Production Apparatus and method of reaching polymers by exposure to UV radiation to produce injectable medical devices
WO2010095055A1 (en) 2009-02-21 2010-08-26 Sofradim Production Crosslinked fibers and method of making same using uv radiation
US9492587B2 (en) * 2009-04-13 2016-11-15 Abbott Cardiovascular Systems Inc. Stent made from an ultra high molecular weight bioabsorbable polymer with high fatigue and fracture resistance
US8246576B2 (en) 2009-05-18 2012-08-21 Surmodics, Inc. Method and apparatus for delivery of a therapeutic agent with an expandable medical device
WO2011119885A1 (en) * 2010-03-25 2011-09-29 Tyco Healthcare Group Lp Enhanced suture braid strength through click chemistry
WO2011117744A2 (en) 2010-03-25 2011-09-29 Sofradim Production Medical devices incorporating functional adhesives
EP2550034B1 (en) 2010-03-25 2015-01-07 Sofradim Production Surgical fasteners and methods for sealing wounds
US11033624B2 (en) 2010-06-02 2021-06-15 Novaflux Inc. Medical item for prevention and treatment of ear infection
CA2804263A1 (en) 2010-06-29 2012-01-12 Tyco Healthcare Group Lp Microwave-powered reactor and method for in situ forming implants
WO2012002944A1 (en) * 2010-06-29 2012-01-05 Artventive Medical Group, Inc. Reducing flow through a tubular structure
JP5984806B2 (en) 2010-06-30 2016-09-06 サーモディクス,インコーポレイティド Lipid coatings for medical devices that deliver bioactive agents
WO2012001532A2 (en) 2010-07-01 2012-01-05 Sofradim Production Medical device with predefined activated cellular integration
AU2011284449B2 (en) 2010-07-27 2015-07-23 Sofradim Production Polymeric fibers having tissue reactive members
US20220175370A1 (en) * 2010-09-30 2022-06-09 Cilag Gmbh International Tissue thickness compensator comprising at least one medicament
US8808350B2 (en) 2011-03-01 2014-08-19 Endologix, Inc. Catheter system and methods of using same
US9861727B2 (en) 2011-05-20 2018-01-09 Surmodics, Inc. Delivery of hydrophobic active agent particles
US10213529B2 (en) 2011-05-20 2019-02-26 Surmodics, Inc. Delivery of coated hydrophobic active agent particles
US8859098B2 (en) * 2012-05-18 2014-10-14 Lord Corporation Acrylic adhesion promoters
CN104334123B (en) 2012-06-07 2019-02-12 意比图密医疗有限公司 Expansion device
US9205175B2 (en) 2012-07-27 2015-12-08 Drexel University Thermosensitive and crosslinkable polymer composite for three-dimensional soft tissue scaffold printing
SG11201502488QA (en) * 2012-09-30 2015-05-28 Univ Singapore Bio-absorbable medicament-eluting ventilation tube
US10538864B2 (en) * 2012-10-24 2020-01-21 Dsm Ip Assets, B.V. Fibers comprising polyesteramide copolymers for drug delivery
JP6438406B2 (en) 2012-11-05 2018-12-12 サーモディクス,インコーポレイテッド Compositions and methods for delivering hydrophobic bioactive agents
US11246963B2 (en) 2012-11-05 2022-02-15 Surmodics, Inc. Compositions and methods for delivery of hydrophobic active agents
US20140336557A1 (en) * 2013-05-10 2014-11-13 Biovation Ii, Llc Biopolymer multi-layer multi-functional medical dressing and method of making same
US9775928B2 (en) 2013-06-18 2017-10-03 Covidien Lp Adhesive barbed filament
US11129793B2 (en) 2013-12-05 2021-09-28 Epitomee Medical Ltd Retentive devices and systems for in-situ release of pharmaceutical active agents
US20150297706A1 (en) 2014-04-18 2015-10-22 Auburn University Particulate Vaccine Formulations for Inducing Innate and Adaptive Immunity
US10293044B2 (en) 2014-04-18 2019-05-21 Auburn University Particulate formulations for improving feed conversion rate in a subject
US10285865B2 (en) 2014-05-02 2019-05-14 Novaflux Inc. Drug-releasing device usable in mucosal body cavities
US20160220498A1 (en) * 2015-01-29 2016-08-04 Aneesh SONI Fully or partially biodegradable device for controlled drug delivery
CN107708736A (en) 2015-06-15 2018-02-16 波士顿科学国际有限公司 Apparatus and method for therapeutic heat processing
JP2018524025A (en) 2015-06-30 2018-08-30 エンドロジックス、インク Lock assembly for coupling guidewire to delivery system
US10661092B2 (en) 2015-10-07 2020-05-26 Boston Scientific Scimed, Inc. Mixture of lafesih magnetic nanoparticles with different curie temperatures for improved inductive heating efficiency for hyperthermia therapy
US20170128632A1 (en) 2015-11-10 2017-05-11 II William Charles McJames Device and method for controlling the release of bioactive and therapeutic agents from an implantable medical device
US10583199B2 (en) 2016-04-26 2020-03-10 Northwestern University Nanocarriers having surface conjugated peptides and uses thereof for sustained local release of drugs
US10898446B2 (en) 2016-12-20 2021-01-26 Surmodics, Inc. Delivery of hydrophobic active agents from hydrophilic polyether block amide copolymer surfaces
US10993807B2 (en) 2017-11-16 2021-05-04 Medtronic Vascular, Inc. Systems and methods for percutaneously supporting and manipulating a septal wall

Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998006439A1 (en) * 1996-08-16 1998-02-19 Osteotech, Inc. Polyetherester copolymers as drug delivery matrices
WO2000057852A2 (en) * 1999-03-26 2000-10-05 Guilford Pharmaceuticals, Inc. Methods and compositions for treating solid tumors
WO2002060508A1 (en) * 2001-01-30 2002-08-08 Isotis N.V. Biodegradable porous scaffold material
WO2002080993A2 (en) * 2001-04-04 2002-10-17 Chienna B.V. Coating for medical devices
US6685957B1 (en) * 1999-09-30 2004-02-03 Chienna B.V. Preparation of fibrous polymer implant containing bioactive agents using wet spinning technique
WO2005011770A2 (en) * 2003-07-30 2005-02-10 Advanced Cardiovascular Systems, Inc. Biologically absorbable coatings for implantable devices
WO2005051449A1 (en) * 2003-11-20 2005-06-09 Advanced Cardiovascular Systems, Inc. Coatings for implantable devices comprising polymers of lactic acid and methods for fabricating the same
WO2005097227A1 (en) * 2004-03-31 2005-10-20 Advanced Cardiovascular Systems, Inc. Biocompatible polyacrylate compositions for medical applications
WO2005097220A1 (en) * 2004-03-29 2005-10-20 Advanced Cardiovascular Systems, Inc. Biologically degradable compositions for coating medical applications

Family Cites Families (59)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US508036A (en) * 1893-11-07 Apparatus for welding
GB1273733A (en) * 1968-07-24 1972-05-10 Scragg & Sons Process for the production of artificial filaments
GB1425577A (en) * 1972-06-30 1976-02-18 Ici Ltd Prosthetics comprising plastics materials
US3959185A (en) * 1974-03-18 1976-05-25 Lever Brothers Company Perfume blend including 2-keto-6-substituted-dioxanes-(1,4)
US3952016A (en) * 1974-03-18 1976-04-20 Lever Brothers Company 2-Keto-6-substituted dioxane-(1,4) compounds
US4052988A (en) * 1976-01-12 1977-10-11 Ethicon, Inc. Synthetic absorbable surgical devices of poly-dioxanone
US4070375A (en) * 1976-08-05 1978-01-24 Chevron Research Company Process for preparing 1,4-dioxan-2-ones
US5002582A (en) * 1982-09-29 1991-03-26 Bio-Metric Systems, Inc. Preparation of polymeric surfaces via covalently attaching polymers
US4979959A (en) * 1986-10-17 1990-12-25 Bio-Metric Systems, Inc. Biocompatible coating for solid surfaces
US4916193A (en) * 1987-12-17 1990-04-10 Allied-Signal Inc. Medical devices fabricated totally or in part from copolymers of recurring units derived from cyclic carbonates and lactides
US4891263A (en) * 1987-12-17 1990-01-02 Allied-Signal Inc. Polycarbonate random copolymer-based fiber compositions and method of melt-spinning same and device
US5120802A (en) * 1987-12-17 1992-06-09 Allied-Signal Inc. Polycarbonate-based block copolymers and devices
US5252701A (en) * 1990-07-06 1993-10-12 American Cyanamid Company Segmented absorbable copolymer
MX9205298A (en) * 1991-09-17 1993-05-01 Steven Carl Quay GASEOUS ULTRASOUND CONTRASTING MEDIA AND METHOD FOR SELECTING GASES TO BE USED AS ULTRASOUND CONTRASTING MEDIA
US5342621A (en) * 1992-09-15 1994-08-30 Advanced Cardiovascular Systems, Inc. Antithrombogenic surface
US5443458A (en) * 1992-12-22 1995-08-22 Advanced Cardiovascular Systems, Inc. Multilayered biodegradable stent and method of manufacture
US5629077A (en) * 1994-06-27 1997-05-13 Advanced Cardiovascular Systems, Inc. Biodegradable mesh and film stent
US5605696A (en) * 1995-03-30 1997-02-25 Advanced Cardiovascular Systems, Inc. Drug loaded polymeric material and method of manufacture
US6261537B1 (en) * 1996-10-28 2001-07-17 Nycomed Imaging As Diagnostic/therapeutic agents having microbubbles coupled to one or more vectors
US5980551A (en) * 1997-02-07 1999-11-09 Endovasc Ltd., Inc. Composition and method for making a biodegradable drug delivery stent
EP0916362B1 (en) * 1997-03-31 2009-07-08 Kabushikikaisha Igaki Iryo Sekkei Stent for vessels
HUP0001256A3 (en) * 1997-04-03 2002-12-28 Univ Johns Hopkins Med Biodegradable terephthalate polyester-poly(phosphate) polymers, compositions, method for making the same and using them
US5843172A (en) * 1997-04-15 1998-12-01 Advanced Cardiovascular Systems, Inc. Porous medicated stent
US5897911A (en) * 1997-08-11 1999-04-27 Advanced Cardiovascular Systems, Inc. Polymer-coated stent structure
US6121027A (en) * 1997-08-15 2000-09-19 Surmodics, Inc. Polybifunctional reagent having a polymeric backbone and photoreactive moieties and bioactive groups
US7208011B2 (en) * 2001-08-20 2007-04-24 Conor Medsystems, Inc. Implantable medical device with drug filled holes
US6419709B1 (en) * 1998-10-02 2002-07-16 Guilford Pharmaceuticals, Inc. Biodegradable terephthalate polyester-poly(Phosphite) compositions, articles, and methods of using the same
US6153212A (en) * 1998-10-02 2000-11-28 Guilford Pharmaceuticals Inc. Biodegradable terephthalate polyester-poly (phosphonate) compositions, articles, and methods of using the same
US6503556B2 (en) * 2000-12-28 2003-01-07 Advanced Cardiovascular Systems, Inc. Methods of forming a coating for a prosthesis
US6503954B1 (en) * 2000-03-31 2003-01-07 Advanced Cardiovascular Systems, Inc. Biocompatible carrier containing actinomycin D and a method of forming the same
US6790228B2 (en) * 1999-12-23 2004-09-14 Advanced Cardiovascular Systems, Inc. Coating for implantable devices and a method of forming the same
US6379381B1 (en) * 1999-09-03 2002-04-30 Advanced Cardiovascular Systems, Inc. Porous prosthesis and a method of depositing substances into the pores
US6287628B1 (en) * 1999-09-03 2001-09-11 Advanced Cardiovascular Systems, Inc. Porous prosthesis and a method of depositing substances into the pores
AU7971000A (en) * 1999-09-30 2001-04-30 Chienna B.V. Poly (ether ester amide) and poly (ether ester urethane) copolymers
US6203551B1 (en) * 1999-10-04 2001-03-20 Advanced Cardiovascular Systems, Inc. Chamber for applying therapeutic substances to an implant device
US20010007083A1 (en) * 1999-12-29 2001-07-05 Roorda Wouter E. Device and active component for inhibiting formation of thrombus-inflammatory cell matrix
US6410643B1 (en) * 2000-03-09 2002-06-25 Surmodics, Inc. Solid phase synthesis method and reagent
US6527801B1 (en) * 2000-04-13 2003-03-04 Advanced Cardiovascular Systems, Inc. Biodegradable drug delivery material for stent
US6395326B1 (en) * 2000-05-31 2002-05-28 Advanced Cardiovascular Systems, Inc. Apparatus and method for depositing a coating onto a surface of a prosthesis
US6555157B1 (en) * 2000-07-25 2003-04-29 Advanced Cardiovascular Systems, Inc. Method for coating an implantable device and system for performing the method
US6451373B1 (en) * 2000-08-04 2002-09-17 Advanced Cardiovascular Systems, Inc. Method of forming a therapeutic coating onto a surface of an implantable prosthesis
US6506437B1 (en) * 2000-10-17 2003-01-14 Advanced Cardiovascular Systems, Inc. Methods of coating an implantable device having depots formed in a surface thereof
US20020087123A1 (en) * 2001-01-02 2002-07-04 Hossainy Syed F.A. Adhesion of heparin-containing coatings to blood-contacting surfaces of medical devices
US6544582B1 (en) * 2001-01-05 2003-04-08 Advanced Cardiovascular Systems, Inc. Method and apparatus for coating an implantable device
US6780424B2 (en) * 2001-03-30 2004-08-24 Charles David Claude Controlled morphologies in polymer drug for release of drugs from polymer films
US6712845B2 (en) * 2001-04-24 2004-03-30 Advanced Cardiovascular Systems, Inc. Coating for a stent and a method of forming the same
US6656506B1 (en) * 2001-05-09 2003-12-02 Advanced Cardiovascular Systems, Inc. Microparticle coated medical device
US6605154B1 (en) * 2001-05-31 2003-08-12 Advanced Cardiovascular Systems, Inc. Stent mounting device
US6572644B1 (en) * 2001-06-27 2003-06-03 Advanced Cardiovascular Systems, Inc. Stent mounting device and a method of using the same to coat a stent
US6565659B1 (en) * 2001-06-28 2003-05-20 Advanced Cardiovascular Systems, Inc. Stent mounting assembly and a method of using the same to coat a stent
US6527863B1 (en) * 2001-06-29 2003-03-04 Advanced Cardiovascular Systems, Inc. Support device for a stent and a method of using the same to coat a stent
US6444318B1 (en) * 2001-07-17 2002-09-03 Surmodics, Inc. Self assembling monolayer compositions
US6818845B2 (en) * 2001-09-27 2004-11-16 Phonak Ag Electromechanical switch
US20030104028A1 (en) * 2001-11-29 2003-06-05 Hossainy Syed F.A. Rate limiting barriers for implantable devices and methods for fabrication thereof
US6663880B1 (en) * 2001-11-30 2003-12-16 Advanced Cardiovascular Systems, Inc. Permeabilizing reagents to increase drug delivery and a method of local delivery
US6866805B2 (en) * 2001-12-27 2005-03-15 Advanced Cardiovascular Systems, Inc. Hybrid intravascular stent
JP2005518469A (en) * 2002-02-26 2005-06-23 シエンナ ビー.ブイ. Biodegradable polymeric materials for bioclinical applications
WO2004108072A2 (en) * 2003-04-10 2004-12-16 3M Innovative Properties Company Delivery of immune response modifier compounds using metal-containing particulate support materials
US7435788B2 (en) * 2003-12-19 2008-10-14 Advanced Cardiovascular Systems, Inc. Biobeneficial polyamide/polyethylene glycol polymers for use with drug eluting stents

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998006439A1 (en) * 1996-08-16 1998-02-19 Osteotech, Inc. Polyetherester copolymers as drug delivery matrices
WO2000057852A2 (en) * 1999-03-26 2000-10-05 Guilford Pharmaceuticals, Inc. Methods and compositions for treating solid tumors
US6685957B1 (en) * 1999-09-30 2004-02-03 Chienna B.V. Preparation of fibrous polymer implant containing bioactive agents using wet spinning technique
WO2002060508A1 (en) * 2001-01-30 2002-08-08 Isotis N.V. Biodegradable porous scaffold material
WO2002080993A2 (en) * 2001-04-04 2002-10-17 Chienna B.V. Coating for medical devices
WO2005011770A2 (en) * 2003-07-30 2005-02-10 Advanced Cardiovascular Systems, Inc. Biologically absorbable coatings for implantable devices
WO2005051449A1 (en) * 2003-11-20 2005-06-09 Advanced Cardiovascular Systems, Inc. Coatings for implantable devices comprising polymers of lactic acid and methods for fabricating the same
WO2005097220A1 (en) * 2004-03-29 2005-10-20 Advanced Cardiovascular Systems, Inc. Biologically degradable compositions for coating medical applications
WO2005097227A1 (en) * 2004-03-31 2005-10-20 Advanced Cardiovascular Systems, Inc. Biocompatible polyacrylate compositions for medical applications

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
BOS, GERT W; VERRIJK, RUUD; FRANSSEN OKKE, BEZEMER, JEROEN, M; HENNINK WIM E; CROMMELIN DAAN J A: "Hydrogels for the controlled release of pharmaceutical proteins", PHARMACEUTICAL TECHNOLOGY, October 2001 (2001-10-01), pages 110 - 120, XP002362432 *
VAN DE WEERT M ET AL: "Reversible aggregation of lysozyme in a biodegradable amphiphilic multiblock copolymer", EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS, ELSEVIER SCIENCE PUBLISHERS B.V., AMSTERDAM, NL, vol. 54, no. 1, July 2002 (2002-07-01), pages 89 - 93, XP004367696, ISSN: 0939-6411 *

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