WO2006010025A3 - Treatment of the autonomic nervous system - Google Patents

Treatment of the autonomic nervous system Download PDF

Info

Publication number
WO2006010025A3
WO2006010025A3 PCT/US2005/024326 US2005024326W WO2006010025A3 WO 2006010025 A3 WO2006010025 A3 WO 2006010025A3 US 2005024326 W US2005024326 W US 2005024326W WO 2006010025 A3 WO2006010025 A3 WO 2006010025A3
Authority
WO
WIPO (PCT)
Prior art keywords
autonomic nervous
nervous system
stimulation
early
patient
Prior art date
Application number
PCT/US2005/024326
Other languages
French (fr)
Other versions
WO2006010025A2 (en
Inventor
Valerio Cigaina
Jiande Chen
Original Assignee
Transneuronix Inc
Valerio Cigaina
Jiande Chen
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Transneuronix Inc, Valerio Cigaina, Jiande Chen filed Critical Transneuronix Inc
Priority to EP05769559.5A priority Critical patent/EP1786515A4/en
Publication of WO2006010025A2 publication Critical patent/WO2006010025A2/en
Publication of WO2006010025A3 publication Critical patent/WO2006010025A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/36128—Control systems
    • A61N1/36135—Control systems using physiological parameters
    • A61N1/36139—Control systems using physiological parameters with automatic adjustment
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
    • A61B5/024—Detecting, measuring or recording pulse rate or heart rate
    • A61B5/02405—Determining heart rate variability
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/316—Modalities, i.e. specific diagnostic methods
    • A61B5/318—Heart-related electrical modalities, e.g. electrocardiography [ECG]
    • A61B5/346—Analysis of electrocardiograms
    • A61B5/349—Detecting specific parameters of the electrocardiograph cycle
    • A61B5/352—Detecting R peaks, e.g. for synchronising diagnostic apparatus; Estimating R-R interval
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/3606—Implantable neurostimulators for stimulating central or peripheral nerve system adapted for a particular treatment
    • A61N1/36082—Cognitive or psychiatric applications, e.g. dementia or Alzheimer's disease
    • A61N1/36085—Eating disorders or obesity
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/40—Detecting, measuring or recording for evaluating the nervous system
    • A61B5/4029—Detecting, measuring or recording for evaluating the nervous system for evaluating the peripheral nervous systems
    • A61B5/4035—Evaluating the autonomic nervous system

Abstract

Systems and methods are provided for modulating the autonomic nervous system by the electrical stimulation of the neuro-muscular system of a patient, and include an implantable electrical system for gastrointestinal stimulation which incorporates a heart rate sensor to indicate the neurovegetative patient condition, to initiate and terminate stimulation at specific locations, and an algorithm to automatically control electrical stimulation frequency, interval, amplitude, or a combination of such parameters for adaptive treatment of obesity, anorexia, other eating disorders, diseases related with the so called 'metabolic syndrome' (e.g., impaired glucose tolerance and diabetes type 2, GERD, systemic hypertension, early arterovascular degeneration, early senility, and the like), and disorders related to a pathologic inbalance of the autonomic nervous system.
PCT/US2005/024326 2004-07-07 2005-07-07 Treatment of the autonomic nervous system WO2006010025A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP05769559.5A EP1786515A4 (en) 2004-07-07 2005-07-07 Treatment of the autonomic nervous system

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US58588504P 2004-07-07 2004-07-07
US60/585,885 2004-07-07
US11/175,626 US7664551B2 (en) 2004-07-07 2005-07-06 Treatment of the autonomic nervous system
US11/175,626 2005-07-06

Publications (2)

Publication Number Publication Date
WO2006010025A2 WO2006010025A2 (en) 2006-01-26
WO2006010025A3 true WO2006010025A3 (en) 2007-02-22

Family

ID=35785754

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2005/024326 WO2006010025A2 (en) 2004-07-07 2005-07-07 Treatment of the autonomic nervous system

Country Status (3)

Country Link
US (2) US7664551B2 (en)
EP (1) EP1786515A4 (en)
WO (1) WO2006010025A2 (en)

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US20100211130A1 (en) 2010-08-19
EP1786515A4 (en) 2013-07-24
US7664551B2 (en) 2010-02-16

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