WO2006015276A3 - Non-curling polyhydroxyalkanoate sutures - Google Patents

Non-curling polyhydroxyalkanoate sutures Download PDF

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Publication number
WO2006015276A3
WO2006015276A3 PCT/US2005/027120 US2005027120W WO2006015276A3 WO 2006015276 A3 WO2006015276 A3 WO 2006015276A3 US 2005027120 W US2005027120 W US 2005027120W WO 2006015276 A3 WO2006015276 A3 WO 2006015276A3
Authority
WO
WIPO (PCT)
Prior art keywords
break
knot
strength
properties
polyhydroxyalkanoate
Prior art date
Application number
PCT/US2005/027120
Other languages
French (fr)
Other versions
WO2006015276A2 (en
Inventor
Said Rizk
Original Assignee
Tepha Inc
Said Rizk
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tepha Inc, Said Rizk filed Critical Tepha Inc
Priority to AT05807559T priority Critical patent/ATE473021T1/en
Priority to DK05807559T priority patent/DK1778305T3/en
Priority to DE200560022197 priority patent/DE602005022197D1/en
Priority to PL05807559T priority patent/PL1778305T3/en
Priority to EP20050807559 priority patent/EP1778305B1/en
Priority to SI200531106T priority patent/SI1778305T1/en
Publication of WO2006015276A2 publication Critical patent/WO2006015276A2/en
Publication of WO2006015276A3 publication Critical patent/WO2006015276A3/en

Links

Classifications

    • D—TEXTILES; PAPER
    • D01—NATURAL OR MAN-MADE THREADS OR FIBRES; SPINNING
    • D01F—CHEMICAL FEATURES IN THE MANUFACTURE OF ARTIFICIAL FILAMENTS, THREADS, FIBRES, BRISTLES OR RIBBONS; APPARATUS SPECIALLY ADAPTED FOR THE MANUFACTURE OF CARBON FILAMENTS
    • D01F6/00—Monocomponent artificial filaments or the like of synthetic polymers; Manufacture thereof
    • D01F6/58—Monocomponent artificial filaments or the like of synthetic polymers; Manufacture thereof from homopolycondensation products
    • D01F6/62—Monocomponent artificial filaments or the like of synthetic polymers; Manufacture thereof from homopolycondensation products from polyesters
    • D01F6/625—Monocomponent artificial filaments or the like of synthetic polymers; Manufacture thereof from homopolycondensation products from polyesters derived from hydroxy-carboxylic acids, e.g. lactones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L17/00—Materials for surgical sutures or for ligaturing blood vessels ; Materials for prostheses or catheters
    • A61L17/06—At least partially resorbable materials
    • A61L17/10—At least partially resorbable materials containing macromolecular materials
    • A61L17/105—Polyesters not covered by A61L17/12
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
    • C08G63/02—Polyesters derived from hydroxycarboxylic acids or from polycarboxylic acids and polyhydroxy compounds
    • C08G63/06—Polyesters derived from hydroxycarboxylic acids or from polycarboxylic acids and polyhydroxy compounds derived from hydroxycarboxylic acids
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2913—Rod, strand, filament or fiber
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T442/00—Fabric [woven, knitted, or nonwoven textile or cloth, etc.]
    • Y10T442/10—Scrim [e.g., open net or mesh, gauze, loose or open weave or knit, etc.]

Abstract

Absorbable polyester fibers, braids, and surgical meshes with improved handling properties have been developed. These devices are preferably derived from biocompatible copolymers or homopolymers of 4-hydroxybutyrate. These devices provide a wider range of in vivo strength retention properties than are currently available and have a decreased tendency to curl, in the preferred embodiement, due to the inclusion of relaxation and annealing steps following extrusion and orientation of the fiber. Filaments prepared according to these methods are characterized by the following physical properties: (i) elongation to break from about 17% to about 85% (ii) Young’s modulus of less than 350,000 psi, (iii) knot to straight ratio (knot strength/tensile strength) of 55-80% or (iv) load at break from 1100 to 4200 grams.
PCT/US2005/027120 2004-08-03 2005-07-29 Non-curling polyhydroxyalkanoate sutures WO2006015276A2 (en)

Priority Applications (6)

Application Number Priority Date Filing Date Title
AT05807559T ATE473021T1 (en) 2004-08-03 2005-07-29 NON-PURLICING POLYHYDROXYALKANOTA SEAMS
DK05807559T DK1778305T3 (en) 2004-08-03 2005-07-29 Non-curly polyhydroxyalkanoate sutures
DE200560022197 DE602005022197D1 (en) 2004-08-03 2005-07-29 NON-CRUSHING POLYHYDROXYALKANOATE SEAMS
PL05807559T PL1778305T3 (en) 2004-08-03 2005-07-29 Non-curling polyhydroxyalkanoate sutures
EP20050807559 EP1778305B1 (en) 2004-08-03 2005-07-29 Non-curling polyhydroxyalkanoate sutures
SI200531106T SI1778305T1 (en) 2004-08-03 2005-07-29 Non-curling polyhydroxyalkanoate sutures

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US59829604P 2004-08-03 2004-08-03
US60/598,296 2004-08-03

Publications (2)

Publication Number Publication Date
WO2006015276A2 WO2006015276A2 (en) 2006-02-09
WO2006015276A3 true WO2006015276A3 (en) 2006-03-23

Family

ID=35636645

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2005/027120 WO2006015276A2 (en) 2004-08-03 2005-07-29 Non-curling polyhydroxyalkanoate sutures

Country Status (10)

Country Link
US (2) US7641825B2 (en)
EP (2) EP1778305B1 (en)
AT (2) ATE473021T1 (en)
CY (1) CY1110815T1 (en)
DE (1) DE602005022197D1 (en)
DK (1) DK1778305T3 (en)
ES (2) ES2362217T3 (en)
PL (1) PL1778305T3 (en)
PT (1) PT1778305E (en)
WO (1) WO2006015276A2 (en)

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