WO2006016913A3 - Method and apparatus for conducting raman spectroscopy - Google Patents

Method and apparatus for conducting raman spectroscopy Download PDF

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Publication number
WO2006016913A3
WO2006016913A3 PCT/US2005/014816 US2005014816W WO2006016913A3 WO 2006016913 A3 WO2006016913 A3 WO 2006016913A3 US 2005014816 W US2005014816 W US 2005014816W WO 2006016913 A3 WO2006016913 A3 WO 2006016913A3
Authority
WO
WIPO (PCT)
Prior art keywords
light
filter
raman signal
receiving
optical fiber
Prior art date
Application number
PCT/US2005/014816
Other languages
French (fr)
Other versions
WO2006016913A2 (en
Inventor
Wang Peidong
Daryoosh Vakhshoori
Yu Shen
Kevin J Knopp
Masud Azimi
Original Assignee
Ahura Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ahura Corp filed Critical Ahura Corp
Priority to JP2007511017A priority Critical patent/JP2007535680A/en
Priority to EP05741216A priority patent/EP1740914A2/en
Publication of WO2006016913A2 publication Critical patent/WO2006016913A2/en
Publication of WO2006016913A3 publication Critical patent/WO2006016913A3/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/65—Raman scattering
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/02—Details
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/02—Details
    • G01J3/0205—Optical elements not provided otherwise, e.g. optical manifolds, diffusers, windows
    • G01J3/0218—Optical elements not provided otherwise, e.g. optical manifolds, diffusers, windows using optical fibers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/02—Details
    • G01J3/0272—Handheld
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/02—Details
    • G01J3/0291—Housings; Spectrometer accessories; Spatial arrangement of elements, e.g. folded path arrangements
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/28—Investigating the spectrum
    • G01J3/44—Raman spectrometry; Scattering spectrometry ; Fluorescence spectrometry
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/12—Generating the spectrum; Monochromators
    • G01J2003/1213—Filters in general, e.g. dichroic, band
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/65—Raman scattering
    • G01N2021/653—Coherent methods [CARS]
    • G01N2021/656—Raman microprobe

Landscapes

  • Physics & Mathematics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • General Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Spectrometry And Color Measurement (AREA)

Abstract

The invention comprises a Raman probe comprising: a first optical fiber receiving laser excitation light from a light source and transmitting the same; a first filter receiving light from the first optical fiber and passing the laser excitation light and blocking spurious signals associated with the light; a second filter receiving light from the first filter and directing the light toward the specimen; a focusing apparatus receiving the light from the second filter, focusing the light on a specimen to generate the Raman signal, and returning the Raman signal to the second filter; wherein the second filter is further configured so that when it receives.the Raman signal from the focusing apparatus, the second filter filters out unwanted laser excitation light before directing the Raman signal to a second optical fiber; that receives the Raman signal from the second filter and transmits the Raman signal to a light analyzer.
PCT/US2005/014816 2004-04-30 2005-04-29 Method and apparatus for conducting raman spectroscopy WO2006016913A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2007511017A JP2007535680A (en) 2004-04-30 2005-04-29 Method and apparatus for performing Raman spectroscopy
EP05741216A EP1740914A2 (en) 2004-04-30 2005-04-29 Method and apparatus for conducting raman spectroscopy

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US56671304P 2004-04-30 2004-04-30
US60/566,713 2004-04-30
US60773504P 2004-09-07 2004-09-07
US60/607,735 2004-09-07

Publications (2)

Publication Number Publication Date
WO2006016913A2 WO2006016913A2 (en) 2006-02-16
WO2006016913A3 true WO2006016913A3 (en) 2007-11-15

Family

ID=35839687

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2005/014816 WO2006016913A2 (en) 2004-04-30 2005-04-29 Method and apparatus for conducting raman spectroscopy

Country Status (4)

Country Link
US (3) US7636157B2 (en)
EP (1) EP1740914A2 (en)
JP (1) JP2007535680A (en)
WO (1) WO2006016913A2 (en)

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JP2007535680A (en) 2007-12-06
EP1740914A2 (en) 2007-01-10
US7636157B2 (en) 2009-12-22
US20050248759A1 (en) 2005-11-10
WO2006016913A2 (en) 2006-02-16
US7420672B2 (en) 2008-09-02
US8107069B2 (en) 2012-01-31
US20080024777A1 (en) 2008-01-31
US20100002228A1 (en) 2010-01-07

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