WO2006029183A3 - Compositions and methods for the diagnosis and treatment of tumor - Google Patents
Compositions and methods for the diagnosis and treatment of tumor Download PDFInfo
- Publication number
- WO2006029183A3 WO2006029183A3 PCT/US2005/031798 US2005031798W WO2006029183A3 WO 2006029183 A3 WO2006029183 A3 WO 2006029183A3 US 2005031798 W US2005031798 W US 2005031798W WO 2006029183 A3 WO2006029183 A3 WO 2006029183A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- compositions
- tumor
- diagnosis
- treatment
- methods
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 3
- 206010028980 Neoplasm Diseases 0.000 title abstract 2
- 238000003745 diagnosis Methods 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 241000124008 Mammalia Species 0.000 abstract 1
Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
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- A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
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- A61K51/10—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
- C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
- C07K16/1036—Retroviridae, e.g. leukemia viruses
- C07K16/1045—Lentiviridae, e.g. HIV, FIV, SIV
- C07K16/1072—Regulatory proteins, e.g. tat, rev, vpt
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- C07—ORGANIC CHEMISTRY
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
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- C07K—PEPTIDES
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- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
- C07K16/303—Liver or Pancreas
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- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
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- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/77—Internalization into the cell
Abstract
Priority Applications (11)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CA002579102A CA2579102A1 (en) | 2004-09-08 | 2005-09-07 | Compositions and methods for the diagnosis and treatment of tumor |
JP2007531286A JP2008512121A (en) | 2004-09-08 | 2005-09-07 | Compositions and methods for diagnosis and treatment of tumors |
MX2007002857A MX2007002857A (en) | 2004-09-08 | 2005-09-07 | Compositions and methods for the diagnosis and treatment of tumor. |
NZ553565A NZ553565A (en) | 2004-09-08 | 2005-09-07 | Compositions and methods for the diagnosis and treatment of tumor using TAT188 antibodies |
AU2005282496A AU2005282496A1 (en) | 2004-09-08 | 2005-09-07 | Compositions and methods for the diagnosis and treatment of tumor |
AT05795139T ATE464323T1 (en) | 2004-09-08 | 2005-09-07 | COMPOSITIONS AND METHODS FOR TUMOR DIAGNOSIS AND TREATMENT |
DE602005020645T DE602005020645D1 (en) | 2004-09-08 | 2005-09-07 | COMPOSITIONS AND METHODS FOR TUMOR DIAGNOSIS AND TREATMENT |
BRPI0515616-5A BRPI0515616A (en) | 2004-09-08 | 2005-09-07 | isolated antibodies that bind to polypeptide, isolated antibodies, methods of inhibiting cell growth, methods of detecting tat188 polypeptide level, interference rna, expression vector, host cell, matter composition, industrialized article, method of inhibiting cancer cell growth and method of treating or preventing cell proliferative dysfunction |
EP05795139A EP1786838B1 (en) | 2004-09-08 | 2005-09-07 | Compositions and methods for the diagnosis and treatment of tumor |
IL181629A IL181629A0 (en) | 2004-09-08 | 2007-02-28 | Compositions and methods for the diagnosis and tretment of tumor |
NO20071791A NO20071791L (en) | 2004-09-08 | 2007-04-04 | Preparations and methods for the diagnosis and treatment of tumor |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10/936,626 | 2004-09-08 | ||
US10/936,626 US7803915B2 (en) | 2001-06-20 | 2004-09-08 | Antibody compositions for the diagnosis and treatment of tumor |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2006029183A2 WO2006029183A2 (en) | 2006-03-16 |
WO2006029183A3 true WO2006029183A3 (en) | 2006-11-16 |
Family
ID=36036964
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2005/031798 WO2006029183A2 (en) | 2004-09-08 | 2005-09-07 | Compositions and methods for the diagnosis and treatment of tumor |
Country Status (19)
Country | Link |
---|---|
US (3) | US7803915B2 (en) |
EP (1) | EP1786838B1 (en) |
JP (1) | JP2008512121A (en) |
KR (1) | KR20070100235A (en) |
CN (1) | CN101263159A (en) |
AT (1) | ATE464323T1 (en) |
AU (1) | AU2005282496A1 (en) |
BR (1) | BRPI0515616A (en) |
CA (1) | CA2579102A1 (en) |
CO (1) | CO6160304A2 (en) |
DE (1) | DE602005020645D1 (en) |
ES (1) | ES2342477T3 (en) |
IL (1) | IL181629A0 (en) |
MX (1) | MX2007002857A (en) |
NO (1) | NO20071791L (en) |
NZ (1) | NZ553565A (en) |
RU (1) | RU2007112932A (en) |
WO (1) | WO2006029183A2 (en) |
ZA (1) | ZA200702322B (en) |
Families Citing this family (55)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PT1392359E (en) | 2001-05-11 | 2010-01-27 | Ludwig Inst For Cancer Res Ltd | Specific binding proteins and uses thereof |
US20100056762A1 (en) | 2001-05-11 | 2010-03-04 | Old Lloyd J | Specific binding proteins and uses thereof |
SI2357006T1 (en) * | 2002-07-31 | 2016-01-29 | Seattle Genetics, Inc. | Drug conjugates and their use for treating cancer, an autoimmune disease or an infectious disease |
EP1618384A2 (en) * | 2003-04-28 | 2006-01-25 | Wyeth | Methods utilising g-protein coupled receptor 54 |
CA2543888C (en) | 2003-11-06 | 2016-01-19 | Seattle Genetics, Inc. | Monomethylvaline compounds capable of conjugation to ligands |
US7399469B2 (en) * | 2004-03-26 | 2008-07-15 | Pdl Biopharma, Inc. | Anti-LFL2 antibodies for the diagnosis, prognosis and treatment of cancer |
NZ551180A (en) | 2004-06-01 | 2009-10-30 | Genentech Inc | Antibody drug conjugates and methods |
ES2715776T3 (en) * | 2004-11-12 | 2019-06-06 | Seattle Genetics Inc | Auristatins that have an aminobenzoic acid unit at the N-terminus |
EP1871418B1 (en) * | 2005-04-19 | 2014-03-19 | Seattle Genetics, Inc. | Humanized anti-cd70 binding agents and uses thereof |
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BRPI0515616A (en) | 2008-07-15 |
ATE464323T1 (en) | 2010-04-15 |
US7749504B2 (en) | 2010-07-06 |
EP1786838A2 (en) | 2007-05-23 |
KR20070100235A (en) | 2007-10-10 |
JP2008512121A (en) | 2008-04-24 |
CA2579102A1 (en) | 2006-03-16 |
IL181629A0 (en) | 2007-07-04 |
MX2007002857A (en) | 2007-09-07 |
ZA200702322B (en) | 2009-11-25 |
CO6160304A2 (en) | 2010-05-20 |
RU2007112932A (en) | 2008-10-20 |
AU2005282496A1 (en) | 2006-03-16 |
DE602005020645D1 (en) | 2010-05-27 |
US20080124331A1 (en) | 2008-05-29 |
WO2006029183A2 (en) | 2006-03-16 |
US20050106644A1 (en) | 2005-05-19 |
US20100303834A1 (en) | 2010-12-02 |
ES2342477T3 (en) | 2010-07-07 |
US7803915B2 (en) | 2010-09-28 |
NO20071791L (en) | 2007-06-08 |
CN101263159A (en) | 2008-09-10 |
EP1786838B1 (en) | 2010-04-14 |
NZ553565A (en) | 2010-05-28 |
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