WO2006037105A3 - Nitric oxide-releasing diazeniumdiolated acrylonitrile-based polymers, and compositions, medical devices, and uses thereof - Google Patents
Nitric oxide-releasing diazeniumdiolated acrylonitrile-based polymers, and compositions, medical devices, and uses thereof Download PDFInfo
- Publication number
- WO2006037105A3 WO2006037105A3 PCT/US2005/035065 US2005035065W WO2006037105A3 WO 2006037105 A3 WO2006037105 A3 WO 2006037105A3 US 2005035065 W US2005035065 W US 2005035065W WO 2006037105 A3 WO2006037105 A3 WO 2006037105A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- nitric oxide
- releasing
- acrylonitrile
- medical devices
- compositions
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/74—Synthetic polymeric materials
- A61K31/765—Polymers containing oxygen
- A61K31/78—Polymers containing oxygen of acrylic acid or derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F8/00—Chemical modification by after-treatment
- C08F8/30—Introducing nitrogen atoms or nitrogen-containing groups
Abstract
Priority Applications (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US11/576,012 US7968664B2 (en) | 2004-09-27 | 2005-09-27 | Nitric oxide-releasing diazeniumdiolated acrylonitrile-based polymers, and compositions, medical devices, and uses thereof |
EP05802080.1A EP1794195B1 (en) | 2004-09-27 | 2005-09-27 | Nitric oxide-releasing diazeniumdiolated acrylonitrile-based polymers, and compositions, medical devices, and uses thereof |
CA2581939A CA2581939C (en) | 2004-09-27 | 2005-09-27 | Nitric oxide-releasing diazeniumdiolated acrylonitrile-based polymers, and compositions, medical devices, and uses thereof |
AU2005289414A AU2005289414B2 (en) | 2004-09-27 | 2005-09-27 | Nitric oxide-releasing diazeniumdiolated acrylonitrile-based polymers, and compositions, medical devices, and uses thereof |
AU2011200972A AU2011200972C1 (en) | 2004-09-27 | 2011-03-04 | Nitric oxide-releasing compounds and uses thereof |
US13/111,613 US8093343B2 (en) | 2004-09-27 | 2011-05-19 | Nitric oxide-releasing diazeniumdiolated compounds |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US61325704P | 2004-09-27 | 2004-09-27 | |
US60/613,257 | 2004-09-27 |
Related Child Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US11/576,012 A-371-Of-International US7968664B2 (en) | 2004-09-27 | 2005-09-27 | Nitric oxide-releasing diazeniumdiolated acrylonitrile-based polymers, and compositions, medical devices, and uses thereof |
US13/111,613 Division US8093343B2 (en) | 2004-09-27 | 2011-05-19 | Nitric oxide-releasing diazeniumdiolated compounds |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2006037105A2 WO2006037105A2 (en) | 2006-04-06 |
WO2006037105A3 true WO2006037105A3 (en) | 2007-10-04 |
Family
ID=35954003
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2005/035065 WO2006037105A2 (en) | 2004-09-27 | 2005-09-27 | Nitric oxide-releasing diazeniumdiolated acrylonitrile-based polymers, and compositions, medical devices, and uses thereof |
Country Status (5)
Country | Link |
---|---|
US (2) | US7968664B2 (en) |
EP (1) | EP1794195B1 (en) |
AU (2) | AU2005289414B2 (en) |
CA (1) | CA2581939C (en) |
WO (1) | WO2006037105A2 (en) |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8282967B2 (en) | 2005-05-27 | 2012-10-09 | The University Of North Carolina At Chapel Hill | Nitric oxide-releasing particles for nitric oxide therapeutics and biomedical applications |
US8591876B2 (en) | 2010-12-15 | 2013-11-26 | Novan, Inc. | Methods of decreasing sebum production in the skin |
US8981139B2 (en) | 2011-02-28 | 2015-03-17 | The University Of North Carolina At Chapel Hill | Tertiary S-nitrosothiol-modified nitric—oxide-releasing xerogels and methods of using the same |
US9526738B2 (en) | 2009-08-21 | 2016-12-27 | Novan, Inc. | Topical gels and methods of using the same |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2005215970A1 (en) | 2004-02-09 | 2005-09-09 | Noxilizer, Inc. | Nitric oxide-releasing molecules |
US7569559B2 (en) * | 2004-02-09 | 2009-08-04 | Noxilizer, Inc. | Nitric oxide-releasing molecules |
US20080241208A1 (en) * | 2005-06-30 | 2008-10-02 | Charles Shanley | Methods, Compositions and Devices For Promoting Anglogenesis |
JP2008544820A (en) | 2005-06-30 | 2008-12-11 | エムシー3, インコーポレイテッド | Nitric oxide coating for medical devices |
JP2009505727A (en) | 2005-08-25 | 2009-02-12 | メドトロニック ヴァスキュラー インコーポレイテッド | Nitric oxide releasing biodegradable polymers useful as medical devices and their coatings |
US20070053952A1 (en) * | 2005-09-07 | 2007-03-08 | Medtronic Vascular, Inc. | Nitric oxide-releasing polymers derived from modified polymers |
EP2015841A4 (en) * | 2006-04-27 | 2010-06-23 | St Jude Medical | Implantable medical device with releasing compound |
US8241619B2 (en) | 2006-05-15 | 2012-08-14 | Medtronic Vascular, Inc. | Hindered amine nitric oxide donating polymers for coating medical devices |
US7811600B2 (en) | 2007-03-08 | 2010-10-12 | Medtronic Vascular, Inc. | Nitric oxide donating medical devices and methods of making same |
US8273828B2 (en) | 2007-07-24 | 2012-09-25 | Medtronic Vascular, Inc. | Methods for introducing reactive secondary amines pendant to polymers backbones that are useful for diazeniumdiolation |
US8852640B2 (en) * | 2008-07-03 | 2014-10-07 | Ecole Polytechnique Federale De Lausanne (Epfl) | Micelles for delivery of nitric oxide |
US8158187B2 (en) | 2008-12-19 | 2012-04-17 | Medtronic Vascular, Inc. | Dry diazeniumdiolation methods for producing nitric oxide releasing medical devices |
US8709465B2 (en) | 2009-04-13 | 2014-04-29 | Medtronic Vascular, Inc. | Diazeniumdiolated phosphorylcholine polymers for nitric oxide release |
WO2011022680A2 (en) | 2009-08-21 | 2011-02-24 | Novan, Inc. | Wound dressings, methods of using the same and methods of forming the same |
US20150132345A1 (en) | 2011-05-09 | 2015-05-14 | Yossef Av-Gay | Nitric oxide-sequestering topical formulations |
US9017653B2 (en) | 2012-06-14 | 2015-04-28 | The Board Of Regents Of The University Of Texas System | Nitric oxide-releasing compositions and methods |
EP2875056B1 (en) * | 2012-07-17 | 2020-05-13 | The U.S.A. As Represented By The Secretary, Department Of Health And Human Services | Nitric oxide-releasing diazeniumdiolated polyvinylpyrrolidone-based polymers, and compositions, medical devices, and uses thereof |
RU2714313C2 (en) * | 2014-08-14 | 2020-02-14 | Ром Энд Хаас Компани | Polymer with released gas |
CA2997896A1 (en) | 2015-09-09 | 2017-03-16 | Advanced Inhalation Therapies (Ait) Ltd. | Nitric oxide inhalation therapy for infants with bronchiolitis |
CN107446096B (en) * | 2017-09-01 | 2020-08-04 | 中车唐山机车车辆有限公司 | Heavy metal ion porous adsorbent and preparation method and application thereof |
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WO1991005551A1 (en) * | 1989-10-18 | 1991-05-02 | The United States Of America, As Represented By The Secretary, U.S. Department Of Commerce | Antihypertensive compositions and use thereof |
US5721365A (en) * | 1989-09-15 | 1998-02-24 | Us Health | N-substituted piperazine NONOates |
EP1300424A1 (en) * | 2001-10-04 | 2003-04-09 | Medtronic AVE Inc. | Highly cross-linked, extremely hydrophobic nitric oxide-releasing polymers and methods for their manufacture and use |
EP1308179A1 (en) * | 2001-10-30 | 2003-05-07 | Boehringer Ingelheim Pharma GmbH & Co.KG | Improved endoprosthetic device |
WO2004012874A1 (en) * | 2002-08-02 | 2004-02-12 | The Government Of The United States Of America, Represented By The Secretary, Dept. Of Health And Human Services | Cross-linked nitric oxide-releasing polyamine coated substrates, compositions comprising same and method of making same |
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US5039705A (en) | 1989-09-15 | 1991-08-13 | The United States Of America As Represented By The Department Of Health And Human Services | Anti-hypertensive compositions of secondary amine-nitric oxide adducts and use thereof |
US5208233A (en) | 1989-09-15 | 1993-05-04 | The United States Of America As Represented By The Department Of Health And Human Services | Anti-hypertensive compositions of secondary amine-nitric oxide adducts and use thereof |
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US5910316A (en) | 1992-08-24 | 1999-06-08 | The United States Of America, As Represented By The Department Of Health And Human Services | Use of nitric oxide-releasing agents to treat impotency |
US5700830A (en) | 1994-11-22 | 1997-12-23 | The United States Of America As Represented By The Department Of Health And Human Services | Use of nitric oxide-releasing agents for reducing metastasis risk |
US5814565A (en) | 1995-02-23 | 1998-09-29 | University Of Utah Research Foundation | Integrated optic waveguide immunosensor |
US5674894A (en) | 1995-05-15 | 1997-10-07 | G.D. Searle & Co. | Amidine derivatives useful as platelet aggregation inhibitors and vasodilators |
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-
2005
- 2005-09-27 US US11/576,012 patent/US7968664B2/en not_active Expired - Fee Related
- 2005-09-27 EP EP05802080.1A patent/EP1794195B1/en active Active
- 2005-09-27 AU AU2005289414A patent/AU2005289414B2/en not_active Ceased
- 2005-09-27 CA CA2581939A patent/CA2581939C/en not_active Expired - Fee Related
- 2005-09-27 WO PCT/US2005/035065 patent/WO2006037105A2/en active Application Filing
-
2011
- 2011-03-04 AU AU2011200972A patent/AU2011200972C1/en not_active Ceased
- 2011-05-19 US US13/111,613 patent/US8093343B2/en not_active Expired - Fee Related
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US5721365A (en) * | 1989-09-15 | 1998-02-24 | Us Health | N-substituted piperazine NONOates |
WO1991005551A1 (en) * | 1989-10-18 | 1991-05-02 | The United States Of America, As Represented By The Secretary, U.S. Department Of Commerce | Antihypertensive compositions and use thereof |
EP1300424A1 (en) * | 2001-10-04 | 2003-04-09 | Medtronic AVE Inc. | Highly cross-linked, extremely hydrophobic nitric oxide-releasing polymers and methods for their manufacture and use |
EP1308179A1 (en) * | 2001-10-30 | 2003-05-07 | Boehringer Ingelheim Pharma GmbH & Co.KG | Improved endoprosthetic device |
WO2004012874A1 (en) * | 2002-08-02 | 2004-02-12 | The Government Of The United States Of America, Represented By The Secretary, Dept. Of Health And Human Services | Cross-linked nitric oxide-releasing polyamine coated substrates, compositions comprising same and method of making same |
Cited By (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8282967B2 (en) | 2005-05-27 | 2012-10-09 | The University Of North Carolina At Chapel Hill | Nitric oxide-releasing particles for nitric oxide therapeutics and biomedical applications |
US8956658B2 (en) | 2005-05-27 | 2015-02-17 | The University Of North Carolina At Chapel Hill | Nitric oxide-releasing particles for nitric oxide therapeutics and biomedical applications |
US8962029B2 (en) | 2005-05-27 | 2015-02-24 | The University Of North Carolina At Chapel Hill | Nitric oxide-releasing particles for nitric oxide therapeutics and biomedical applications |
US9403851B2 (en) | 2005-05-27 | 2016-08-02 | The University Of North Carolina At Chapel Hill | Nitric oxide-releasing particles for nitric oxide therapeutics and biomedical applications |
US9403852B2 (en) | 2005-05-27 | 2016-08-02 | The University Of North Carolina At Chapel Hill | Nitric oxide-releasing particles for nitric oxide therapeutics and biomedical applications |
US9526738B2 (en) | 2009-08-21 | 2016-12-27 | Novan, Inc. | Topical gels and methods of using the same |
US8591876B2 (en) | 2010-12-15 | 2013-11-26 | Novan, Inc. | Methods of decreasing sebum production in the skin |
US8981139B2 (en) | 2011-02-28 | 2015-03-17 | The University Of North Carolina At Chapel Hill | Tertiary S-nitrosothiol-modified nitric—oxide-releasing xerogels and methods of using the same |
Also Published As
Publication number | Publication date |
---|---|
AU2011200972B2 (en) | 2012-01-12 |
EP1794195A2 (en) | 2007-06-13 |
AU2011200972A1 (en) | 2011-03-24 |
US20070292471A1 (en) | 2007-12-20 |
EP1794195B1 (en) | 2014-12-17 |
AU2011200972C1 (en) | 2012-05-24 |
AU2005289414A1 (en) | 2006-04-06 |
US8093343B2 (en) | 2012-01-10 |
AU2005289414B2 (en) | 2010-12-09 |
CA2581939C (en) | 2013-01-08 |
US20110282060A1 (en) | 2011-11-17 |
WO2006037105A2 (en) | 2006-04-06 |
US7968664B2 (en) | 2011-06-28 |
CA2581939A1 (en) | 2006-04-06 |
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