WO2006042075A3 - System and methods for assessing the neuromuscular pathway prior to nerve testing - Google Patents

System and methods for assessing the neuromuscular pathway prior to nerve testing Download PDF

Info

Publication number
WO2006042075A3
WO2006042075A3 PCT/US2005/036089 US2005036089W WO2006042075A3 WO 2006042075 A3 WO2006042075 A3 WO 2006042075A3 US 2005036089 W US2005036089 W US 2005036089W WO 2006042075 A3 WO2006042075 A3 WO 2006042075A3
Authority
WO
WIPO (PCT)
Prior art keywords
nerve
assessing
methods
neuromuscular pathway
neuromuscular
Prior art date
Application number
PCT/US2005/036089
Other languages
French (fr)
Other versions
WO2006042075A2 (en
Inventor
James Gharib
Allen Farquhar
Kelli Howell
Doug Layman
Albert Pothier
Original Assignee
Nuvasive Inc
James Gharib
Allen Farquhar
Kelli Howell
Doug Layman
Albert Pothier
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nuvasive Inc, James Gharib, Allen Farquhar, Kelli Howell, Doug Layman, Albert Pothier filed Critical Nuvasive Inc
Priority to US11/665,038 priority Critical patent/US8538539B2/en
Priority to EP05804448A priority patent/EP1804660A4/en
Publication of WO2006042075A2 publication Critical patent/WO2006042075A2/en
Publication of WO2006042075A3 publication Critical patent/WO2006042075A3/en
Priority to US14/029,606 priority patent/US8989866B2/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/02Surgical instruments, devices or methods, e.g. tourniquets for holding wounds open; Tractors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/16Bone cutting, breaking or removal means other than saws, e.g. Osteoclasts; Drills or chisels for bones; Trepans
    • A61B17/17Guides or aligning means for drills, mills, pins or wires
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/56Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws, setting implements or the like
    • A61B17/88Osteosynthesis instruments; Methods or means for implanting or extracting internal or external fixation devices
    • A61B17/8875Screwdrivers, spanners or wrenches
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/103Detecting, measuring or recording devices for testing the shape, pattern, colour, size or movement of the body or parts thereof, for diagnostic purposes
    • A61B5/11Measuring movement of the entire body or parts thereof, e.g. head or hand tremor, mobility of a limb
    • A61B5/1104Measuring movement of the entire body or parts thereof, e.g. head or hand tremor, mobility of a limb induced by stimuli or drugs
    • A61B5/1106Measuring movement of the entire body or parts thereof, e.g. head or hand tremor, mobility of a limb induced by stimuli or drugs to assess neuromuscular blockade, e.g. to estimate depth of anaesthesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/24Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/24Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/316Modalities, i.e. specific diagnostic methods
    • A61B5/389Electromyography [EMG]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B90/00Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
    • A61B90/06Measuring instruments not otherwise provided for
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/02Details
    • A61N1/04Electrodes
    • A61N1/0404Electrodes for external use
    • A61N1/0408Use-related aspects
    • A61N1/0456Specially adapted for transcutaneous electrical nerve stimulation [TENS]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2505/00Evaluating, monitoring or diagnosing in the context of a particular type of medical care
    • A61B2505/05Surgical care
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2562/00Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
    • A61B2562/04Arrangements of multiple sensors of the same type
    • A61B2562/046Arrangements of multiple sensors of the same type in a matrix array
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/68Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6801Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
    • A61B5/6813Specially adapted to be attached to a specific body part
    • A61B5/6823Trunk, e.g., chest, back, abdomen, hip

Abstract

The present invention involves a system and methods for assessing the state of the neuromuscular pathway to ensure further nerve tests aimed at detecting at least one of a breach in a pedicle wall, nerve proximity, nerve direction, and nerve pathology, are not conducted when neuromuscular blockade levels may decrease the reliability of the results.
PCT/US2005/036089 2004-10-07 2005-10-07 System and methods for assessing the neuromuscular pathway prior to nerve testing WO2006042075A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
US11/665,038 US8538539B2 (en) 2004-10-07 2005-10-07 System and methods for assessing the neuromuscular pathway prior to nerve testing
EP05804448A EP1804660A4 (en) 2004-10-07 2005-10-07 System and methods for assessing the neuromuscular pathway prior to nerve testing
US14/029,606 US8989866B2 (en) 2004-10-07 2013-09-17 System and methods for assessing the neuromuscular pathway prior to nerve testing

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US61714204P 2004-10-07 2004-10-07
US60/617,142 2004-10-07
US62249404P 2004-10-26 2004-10-26
US60/622,494 2004-10-26
US72142405P 2005-09-27 2005-09-27
US60/721,424 2005-09-27

Related Child Applications (2)

Application Number Title Priority Date Filing Date
US11/665,038 A-371-Of-International US8538539B2 (en) 2004-10-07 2005-10-07 System and methods for assessing the neuromuscular pathway prior to nerve testing
US14/029,606 Continuation US8989866B2 (en) 2004-10-07 2013-09-17 System and methods for assessing the neuromuscular pathway prior to nerve testing

Publications (2)

Publication Number Publication Date
WO2006042075A2 WO2006042075A2 (en) 2006-04-20
WO2006042075A3 true WO2006042075A3 (en) 2006-07-27

Family

ID=36148935

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2005/036089 WO2006042075A2 (en) 2004-10-07 2005-10-07 System and methods for assessing the neuromuscular pathway prior to nerve testing

Country Status (3)

Country Link
US (2) US8538539B2 (en)
EP (1) EP1804660A4 (en)
WO (1) WO2006042075A2 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8313430B1 (en) 2006-01-11 2012-11-20 Nuvasive, Inc. Surgical access system and related methods

Families Citing this family (90)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1804660A4 (en) 2004-10-07 2009-11-11 Nuvasive Inc System and methods for assessing the neuromuscular pathway prior to nerve testing
US9101386B2 (en) 2004-10-15 2015-08-11 Amendia, Inc. Devices and methods for treating tissue
US7887538B2 (en) * 2005-10-15 2011-02-15 Baxano, Inc. Methods and apparatus for tissue modification
US20080161809A1 (en) * 2006-10-03 2008-07-03 Baxano, Inc. Articulating Tissue Cutting Device
US8048080B2 (en) 2004-10-15 2011-11-01 Baxano, Inc. Flexible tissue rasp
US7959577B2 (en) * 2007-09-06 2011-06-14 Baxano, Inc. Method, system, and apparatus for neural localization
US20070213734A1 (en) * 2006-03-13 2007-09-13 Bleich Jeffery L Tissue modification barrier devices and methods
US8062300B2 (en) * 2006-05-04 2011-11-22 Baxano, Inc. Tissue removal with at least partially flexible devices
US20100004654A1 (en) * 2008-07-01 2010-01-07 Schmitz Gregory P Access and tissue modification systems and methods
US7738968B2 (en) * 2004-10-15 2010-06-15 Baxano, Inc. Devices and methods for selective surgical removal of tissue
US8221397B2 (en) 2004-10-15 2012-07-17 Baxano, Inc. Devices and methods for tissue modification
US9247952B2 (en) * 2004-10-15 2016-02-02 Amendia, Inc. Devices and methods for tissue access
US7578819B2 (en) * 2005-05-16 2009-08-25 Baxano, Inc. Spinal access and neural localization
US20080103504A1 (en) * 2006-10-30 2008-05-01 Schmitz Gregory P Percutaneous spinal stenosis treatment
US20060122458A1 (en) * 2004-10-15 2006-06-08 Baxano, Inc. Devices and methods for tissue access
US20110190772A1 (en) 2004-10-15 2011-08-04 Vahid Saadat Powered tissue modification devices and methods
US8257356B2 (en) * 2004-10-15 2012-09-04 Baxano, Inc. Guidewire exchange systems to treat spinal stenosis
US20100331883A1 (en) * 2004-10-15 2010-12-30 Schmitz Gregory P Access and tissue modification systems and methods
US7738969B2 (en) * 2004-10-15 2010-06-15 Baxano, Inc. Devices and methods for selective surgical removal of tissue
WO2006044727A2 (en) * 2004-10-15 2006-04-27 Baxano, Inc. Devices and methods for tissue removal
US8617163B2 (en) 2004-10-15 2013-12-31 Baxano Surgical, Inc. Methods, systems and devices for carpal tunnel release
US20090171381A1 (en) * 2007-12-28 2009-07-02 Schmitz Gregory P Devices, methods and systems for neural localization
US7938830B2 (en) * 2004-10-15 2011-05-10 Baxano, Inc. Powered tissue modification devices and methods
US8430881B2 (en) * 2004-10-15 2013-04-30 Baxano, Inc. Mechanical tissue modification devices and methods
US7857813B2 (en) 2006-08-29 2010-12-28 Baxano, Inc. Tissue access guidewire system and method
EP2409641B1 (en) * 2005-02-02 2017-07-05 NuVasive, Inc. System for performing neurophysiologic assessments during spine surgery
WO2007035925A2 (en) * 2005-09-22 2007-03-29 Nuvasive, Inc. System and methods for performing pedicle integrity assessments of the thoracic spine
US8568317B1 (en) 2005-09-27 2013-10-29 Nuvasive, Inc. System and methods for nerve monitoring
US8366712B2 (en) 2005-10-15 2013-02-05 Baxano, Inc. Multiple pathways for spinal nerve root decompression from a single access point
US20080091227A1 (en) * 2006-08-25 2008-04-17 Baxano, Inc. Surgical probe and method of making
US8062298B2 (en) 2005-10-15 2011-11-22 Baxano, Inc. Flexible tissue removal devices and methods
US8092456B2 (en) * 2005-10-15 2012-01-10 Baxano, Inc. Multiple pathways for spinal nerve root decompression from a single access point
US7906239B2 (en) * 2006-03-06 2011-03-15 Sony Corporation Cathode active material, method for producing the same, and nonaqueous electrolyte secondary battery
US7869885B2 (en) * 2006-04-28 2011-01-11 Cyberonics, Inc Threshold optimization for tissue stimulation therapy
US8255045B2 (en) * 2007-04-03 2012-08-28 Nuvasive, Inc. Neurophysiologic monitoring system
US10002545B2 (en) * 2007-10-10 2018-06-19 Jennifer Robin Hanners System and method for controlling gaming technology, musical instruments and environmental settings via detection of neuromuscular activity
US8343079B2 (en) * 2007-10-18 2013-01-01 Innovative Surgical Solutions, Llc Neural monitoring sensor
WO2009055034A1 (en) 2007-10-24 2009-04-30 Nuvasive, Inc. Surgical trajectory monitoring system and related methods
JP5004771B2 (en) * 2007-11-22 2012-08-22 株式会社リコー Image forming apparatus
US8192436B2 (en) 2007-12-07 2012-06-05 Baxano, Inc. Tissue modification devices
US8572876B2 (en) * 2008-05-02 2013-11-05 Taser International, Inc. Systems and methods for detecting use of an electronic control device
US9314253B2 (en) 2008-07-01 2016-04-19 Amendia, Inc. Tissue modification devices and methods
US8409206B2 (en) 2008-07-01 2013-04-02 Baxano, Inc. Tissue modification devices and methods
US8398641B2 (en) 2008-07-01 2013-03-19 Baxano, Inc. Tissue modification devices and methods
MX348805B (en) * 2008-07-14 2017-06-28 Baxano Inc Tissue modification devices.
US8137285B1 (en) 2008-08-26 2012-03-20 Rhythmlink International, Llc Monopolar stimulation probe system
MX2011009165A (en) 2009-03-13 2011-09-26 Baxano Inc Flexible neural localization devices and methods.
US8394102B2 (en) * 2009-06-25 2013-03-12 Baxano, Inc. Surgical tools for treatment of spinal stenosis
US20110230785A1 (en) * 2010-03-16 2011-09-22 ProNerve, LLC Somatosensory Evoked Potential (SSEP) Automated Alert System
US9392953B1 (en) * 2010-09-17 2016-07-19 Nuvasive, Inc. Neurophysiologic monitoring
WO2012040206A1 (en) 2010-09-20 2012-03-29 Synthes Usa, Llc Spinal access retractor
JP5657988B2 (en) * 2010-10-08 2015-01-21 日本光電工業株式会社 Biological signal display device
US9949651B2 (en) 2011-11-01 2018-04-24 DePuy Synthes Products, Inc. Intraoperative neurophysiological monitoring system
JP2015506245A (en) * 2012-01-27 2015-03-02 ティー4・アナリティクス・リミテッド・ライアビリティ・カンパニー Anesthesia monitoring system and method for monitoring anesthesia
US20130204156A1 (en) * 2012-01-27 2013-08-08 T4 Analytics Llc Methods and Systems For Assessing Muscle Electrical Activity in Response to Stimulation of a Motor Nerve
JP5748868B2 (en) * 2012-01-30 2015-07-15 三菱電機株式会社 Equipment management device, equipment management system, equipment management method, and program
US9655505B1 (en) 2012-02-06 2017-05-23 Nuvasive, Inc. Systems and methods for performing neurophysiologic monitoring during spine surgery
US9066701B1 (en) 2012-02-06 2015-06-30 Nuvasive, Inc. Systems and methods for performing neurophysiologic monitoring during spine surgery
US20140107524A1 (en) * 2012-10-12 2014-04-17 Mayo Foundation For Medical Education And Research Neuromuscular monitoring display system
US11259737B2 (en) 2012-11-06 2022-03-01 Nuvasive, Inc. Systems and methods for performing neurophysiologic monitoring during spine surgery
US11877860B2 (en) 2012-11-06 2024-01-23 Nuvasive, Inc. Systems and methods for performing neurophysiologic monitoring during spine surgery
US9757067B1 (en) 2012-11-09 2017-09-12 Nuvasive, Inc. Systems and methods for performing neurophysiologic monitoring during spine surgery
US9757072B1 (en) 2013-02-11 2017-09-12 Nuvasive, Inc. Waveform marker placement algorithm for use in neurophysiologic monitoring
JP2016508400A (en) 2013-02-15 2016-03-22 アカシア・デザインズ・ベスローテン・フェンノートシャップ Electrode system for use in medical monitoring systems
EP3019234A4 (en) * 2013-07-11 2017-04-26 Analytica Limited Stimulation and electromyography detection
US10478096B2 (en) 2013-08-13 2019-11-19 Innovative Surgical Solutions. Neural event detection
US10478097B2 (en) 2013-08-13 2019-11-19 Innovative Surgical Solutions Neural event detection
US10449002B2 (en) 2013-09-20 2019-10-22 Innovative Surgical Solutions, Llc Method of mapping a nerve
US10376209B2 (en) 2013-09-20 2019-08-13 Innovative Surgical Solutions, Llc Neural locating method
US10376208B2 (en) 2013-09-20 2019-08-13 Innovative Surgical Solutions, Llc Nerve mapping system
US10022090B2 (en) 2013-10-18 2018-07-17 Atlantic Health System, Inc. Nerve protecting dissection device
US11166672B2 (en) 2013-10-18 2021-11-09 Atlantic Health System, Inc. Nerve protecting dissection device
US10512413B2 (en) 2014-08-26 2019-12-24 Avent, Inc. Method and system for identification of source of chronic pain and treatment
US10420480B1 (en) 2014-09-16 2019-09-24 Nuvasive, Inc. Systems and methods for performing neurophysiologic monitoring
EP3223692B1 (en) * 2014-11-26 2022-02-02 SafeOp Surgical, Inc. A device and means of assessing neuromuscular junction status with higher fidelity
JP6577858B2 (en) * 2015-12-21 2019-09-18 日本光電工業株式会社 Muscle relaxation monitoring device, muscle relaxation monitoring method, and muscle relaxation monitoring program
US10321833B2 (en) 2016-10-05 2019-06-18 Innovative Surgical Solutions. Neural locating method
JP7170631B2 (en) 2016-10-05 2022-11-14 ニューヴェイジヴ,インコーポレイテッド Surgical navigation system and related methods
US10132607B2 (en) 2016-11-03 2018-11-20 Edge Surgical, Inc. Surgical depth instrument having neuromonitoring capabilities
US10939867B2 (en) 2017-03-10 2021-03-09 Robert S. Bray Paralysis monitoring system
US10792080B2 (en) 2017-06-14 2020-10-06 Edge Surgical, Inc. Devices for minimally invasive procedures
EP3760280A1 (en) 2017-06-16 2021-01-06 Alphatec Spine, Inc. Systems, methods, and devices for detecting the threshold of nerve-muscle response using variable frequency stimulation
CN111818847A (en) 2018-03-05 2020-10-23 爱知外科股份有限公司 Hand-held device for use in medical procedures
US10869616B2 (en) 2018-06-01 2020-12-22 DePuy Synthes Products, Inc. Neural event detection
CA3110146C (en) * 2018-08-31 2023-05-23 Avation Medical, Inc. System, method, and apparatus for applying transcutaneous electrical stimulation
US10870002B2 (en) 2018-10-12 2020-12-22 DePuy Synthes Products, Inc. Neuromuscular sensing device with multi-sensor array
US11612440B2 (en) 2019-09-05 2023-03-28 Nuvasive, Inc. Surgical instrument tracking devices and related methods
US20210076982A1 (en) * 2019-09-12 2021-03-18 GE Precision Healthcare LLC Method and System for Monitoring Depth of Muscle Relaxation of a Patient
US11399777B2 (en) 2019-09-27 2022-08-02 DePuy Synthes Products, Inc. Intraoperative neural monitoring system and method
US20220296326A1 (en) 2021-03-22 2022-09-22 Nuvasive, Inc. Multi-user surgical cart

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6224549B1 (en) * 1999-04-20 2001-05-01 Nicolet Biomedical, Inc. Medical signal monitoring and display
WO2001037728A1 (en) * 1999-11-24 2001-05-31 Nuvasive, Inc. Electromyography system
US6259945B1 (en) * 1999-04-30 2001-07-10 Uromed Corporation Method and device for locating a nerve
US20020198572A1 (en) * 1999-05-29 2002-12-26 Medtronic, Inc. Peripheral nerve stimulation apparatus
US6500128B2 (en) * 2000-06-08 2002-12-31 Nuvasive, Inc. Nerve movement and status detection system and method
US6671547B2 (en) * 2001-06-13 2003-12-30 Koninklijke Philips Electronics N.V. Adaptive analysis method for an electrotherapy device and apparatus

Family Cites Families (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2736002A (en) 1956-02-21 oriel
US3785368A (en) 1971-08-23 1974-01-15 Carthy T Mc Abnormal nerve pressure locus detector and method
US4291705A (en) 1979-09-10 1981-09-29 The Regents Of The University Of California Neuromuscular block monitor
US4545374A (en) 1982-09-03 1985-10-08 Jacobson Robert E Method and instruments for performing a percutaneous lumbar diskectomy
US5277197A (en) * 1986-12-08 1994-01-11 Physical Health Device, Inc. Microprocessor controlled system for unsupervised EMG feedback and exercise training
US4962766A (en) 1989-07-19 1990-10-16 Herzon Garrett D Nerve locator and stimulator
US5269785A (en) 1990-06-28 1993-12-14 Bonutti Peter M Apparatus and method for tissue removal
US5284153A (en) 1992-04-14 1994-02-08 Brigham And Women's Hospital Method for locating a nerve and for protecting nerves from injury during surgery
US5474558A (en) 1992-04-30 1995-12-12 Neubardt; Seth L. Procedure and system for spinal pedicle screw insertion
US5575284A (en) 1994-04-01 1996-11-19 University Of South Florida Portable pulse oximeter
US6038469A (en) 1994-10-07 2000-03-14 Ortivus Ab Myocardial ischemia and infarction analysis and monitoring method and apparatus
US5601608A (en) 1995-02-02 1997-02-11 Pacesetter, Inc. Methods and apparatus for applying charge-balanced antiarrhythmia shocks
AU5448496A (en) 1995-04-10 1996-10-30 St. Luke's-Roosevelt Hospital Peripheral nerve stimulation device for unassisted nerve blo ckade
US5775331A (en) 1995-06-07 1998-07-07 Uromed Corporation Apparatus and method for locating a nerve
US5806522A (en) 1995-08-15 1998-09-15 Katims; Jefferson Jacob Digital automated current perception threshold (CPT) determination device and method
US5779642A (en) 1996-01-16 1998-07-14 Nightengale; Christopher Interrogation device and method
US5792044A (en) 1996-03-22 1998-08-11 Danek Medical, Inc. Devices and methods for percutaneous surgery
US5810747A (en) 1996-08-21 1998-09-22 Interactive Remote Site Technology, Inc. Remote site medical intervention system
US5928158A (en) 1997-03-25 1999-07-27 Aristides; Arellano Medical instrument with nerve sensor
US6306100B1 (en) 1997-12-16 2001-10-23 Richard L. Prass Intraoperative neurophysiological monitoring system
US6027456A (en) 1998-07-10 2000-02-22 Advanced Neuromodulation Systems, Inc. Apparatus and method for positioning spinal cord stimulation leads
US6366813B1 (en) 1998-08-05 2002-04-02 Dilorenzo Daniel J. Apparatus and method for closed-loop intracranical stimulation for optimal control of neurological disease
US6292701B1 (en) 1998-08-12 2001-09-18 Medtronic Xomed, Inc. Bipolar electrical stimulus probe with planar electrodes
US6104957A (en) 1998-08-21 2000-08-15 Alo; Kenneth M. Epidural nerve root stimulation with lead placement method
US6451015B1 (en) 1998-11-18 2002-09-17 Sherwood Services Ag Method and system for menu-driven two-dimensional display lesion generator
US6266558B1 (en) 1998-12-01 2001-07-24 Neurometrix, Inc. Apparatus and method for nerve conduction measurements with automatic setting of stimulus intensity
US6564078B1 (en) 1998-12-23 2003-05-13 Nuvasive, Inc. Nerve surveillance cannula systems
US6393325B1 (en) 1999-01-07 2002-05-21 Advanced Bionics Corporation Directional programming for implantable electrode arrays
US6901928B2 (en) 1999-05-04 2005-06-07 Paul G. Loubser Superglottic and peri-laryngeal apparatus for supraglottic airway insertion
US6334068B1 (en) 1999-09-14 2001-12-25 Medtronic Xomed, Inc. Intraoperative neuroelectrophysiological monitor
US6466817B1 (en) 1999-11-24 2002-10-15 Nuvasive, Inc. Nerve proximity and status detection system and method
US6389312B1 (en) 2000-07-21 2002-05-14 General Electric Company Method and system having simplified neuromuscular transmission scoring
US7089059B1 (en) 2000-11-03 2006-08-08 Pless Benjamin D Predicting susceptibility to neurological dysfunction based on measured neural electrophysiology
US20030105503A1 (en) * 2001-06-08 2003-06-05 Nuvasive, Inc. Relative nerve movement and status detection system and method
EP1417000B1 (en) 2001-07-11 2018-07-11 Nuvasive, Inc. System for determining nerve proximity during surgery
US6926728B2 (en) 2001-07-18 2005-08-09 St. Francis Medical Technologies, Inc. Curved dilator and method
EP2481338A3 (en) 2001-09-25 2012-09-05 Nuvasive, Inc. System for performing surgical procedures and assessments
DE60238861D1 (en) * 2001-10-30 2011-02-17 Nuvasive Inc SYSTEM FOR PERCUTANT INVESTIGATIONS OF PEDICLE INTEGRITY
US7664544B2 (en) 2002-10-30 2010-02-16 Nuvasive, Inc. System and methods for performing percutaneous pedicle integrity assessments
AU2004263152B2 (en) 2003-08-05 2009-08-27 Nuvasive, Inc. Systems and methods for performing dynamic pedicle integrity assessments
JP4463819B2 (en) 2003-09-25 2010-05-19 ヌヴァシヴ インコーポレイテッド Surgical access system
US7905840B2 (en) 2003-10-17 2011-03-15 Nuvasive, Inc. Surgical access system and related methods
EP1804660A4 (en) 2004-10-07 2009-11-11 Nuvasive Inc System and methods for assessing the neuromuscular pathway prior to nerve testing
EP2409641B1 (en) 2005-02-02 2017-07-05 NuVasive, Inc. System for performing neurophysiologic assessments during spine surgery
WO2007038290A2 (en) 2005-09-22 2007-04-05 Nuvasive, Inc. Multi-channel stimulation threshold detection algorithm for use in neurophysiology monitoring

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6224549B1 (en) * 1999-04-20 2001-05-01 Nicolet Biomedical, Inc. Medical signal monitoring and display
US6259945B1 (en) * 1999-04-30 2001-07-10 Uromed Corporation Method and device for locating a nerve
US20020198572A1 (en) * 1999-05-29 2002-12-26 Medtronic, Inc. Peripheral nerve stimulation apparatus
WO2001037728A1 (en) * 1999-11-24 2001-05-31 Nuvasive, Inc. Electromyography system
US6500128B2 (en) * 2000-06-08 2002-12-31 Nuvasive, Inc. Nerve movement and status detection system and method
US6671547B2 (en) * 2001-06-13 2003-12-30 Koninklijke Philips Electronics N.V. Adaptive analysis method for an electrotherapy device and apparatus

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of EP1804660A4 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8313430B1 (en) 2006-01-11 2012-11-20 Nuvasive, Inc. Surgical access system and related methods
US8827900B1 (en) 2006-01-11 2014-09-09 Nuvasive, Inc. Surgical access system and related methods

Also Published As

Publication number Publication date
US20090018610A1 (en) 2009-01-15
EP1804660A2 (en) 2007-07-11
US8989866B2 (en) 2015-03-24
US20140148796A1 (en) 2014-05-29
EP1804660A4 (en) 2009-11-11
US8538539B2 (en) 2013-09-17
WO2006042075A2 (en) 2006-04-20

Similar Documents

Publication Publication Date Title
WO2006042075A3 (en) System and methods for assessing the neuromuscular pathway prior to nerve testing
WO2012044699A3 (en) Systems and methods for detecting intrathecal penetration
WO2007081804A3 (en) Regulators of nfat
EP3070474A3 (en) Methods and compositions for diagnosis and prognosis of renal injury and renal failure
WO2009088816A8 (en) Systems and methods for well data analysis
WO2009085356A3 (en) Methods of using and constructing nanosensor platforms
ZA200807948B (en) DNA Conformation (loop structures) in normal and abnormal gene expression
WO2008153705A3 (en) Methods of treating, diagnosing and detecting fgf21-associated disorders
WO2008154086A9 (en) Identification of a defect or operating characteristic
WO2006089091A3 (en) Methods for detecting minimum residual disease
EP2767833A3 (en) Methods and compositions for diagnosis and prognosis of renal injury and renal failure
PT1949285T (en) Systems and methods for treating, diagnosing and predicting the occurrence of a medical condition
ZA200806064B (en) System and method for detecting rail break or vehicle
WO2011011426A8 (en) Methods for assessing disease risk
WO2008055112A3 (en) Methods of treating autism and autism spectrum disorders
BRPI0608079A2 (en) sympathetic tone evaluation
WO2006102498A3 (en) Methods of diagnosing fetal trisomy 13 or a risk of fetal trisomy 13 during pregnancy
WO2006124526A3 (en) Method for assessing the effectiveness of a treatment regimen by determining zonulin
WO2009007844A3 (en) Breathalyzer test device
WO2007048067A3 (en) C-kit oncogene mutations in melanoma
WO2005108988A3 (en) Real time method of detecting acute inflammatory conditions
WO2007134028A3 (en) Biomarkers for depression and methods using the same
WO2010099211A3 (en) Compositions and methods for diagnosing and preventing spontaneous preterm birth
WO2006031986A3 (en) Methods and compositions for diagnosing neoplastic disease
WO2013090857A8 (en) Identification of two novel biomarkers for niemann-pick disease type c

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BW BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE EG ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KM KP KR KZ LC LK LR LS LT LU LV LY MA MD MG MK MN MW MX MZ NA NG NI NO NZ OM PG PH PL PT RO RU SC SD SE SG SK SL SM SY TJ TM TN TR TT TZ UA UG US UZ VC VN YU ZA ZM ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): GM KE LS MW MZ NA SD SL SZ TZ UG ZM ZW AM AZ BY KG KZ MD RU TJ TM AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LT LU LV MC NL PL PT RO SE SI SK TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG

WWE Wipo information: entry into national phase

Ref document number: 11665038

Country of ref document: US

NENP Non-entry into the national phase

Ref country code: DE

WWE Wipo information: entry into national phase

Ref document number: 2005804448

Country of ref document: EP

WWP Wipo information: published in national office

Ref document number: 2005804448

Country of ref document: EP