WO2006065762A3 - Surface enhanced raman spectroscopy using shaped gold nanoparticles - Google Patents

Surface enhanced raman spectroscopy using shaped gold nanoparticles Download PDF

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Publication number
WO2006065762A3
WO2006065762A3 PCT/US2005/044963 US2005044963W WO2006065762A3 WO 2006065762 A3 WO2006065762 A3 WO 2006065762A3 US 2005044963 W US2005044963 W US 2005044963W WO 2006065762 A3 WO2006065762 A3 WO 2006065762A3
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WO
WIPO (PCT)
Prior art keywords
analyte
relates
nanoparticle
raman spectroscopy
gold nanoparticles
Prior art date
Application number
PCT/US2005/044963
Other languages
French (fr)
Other versions
WO2006065762A2 (en
Inventor
Catherine J Murphy
Tapan K Sau
Christopher J Orendorff
Anand M Gole
Original Assignee
Univ South Carolina
Catherine J Murphy
Tapan K Sau
Christopher J Orendorff
Anand M Gole
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ South Carolina, Catherine J Murphy, Tapan K Sau, Christopher J Orendorff, Anand M Gole filed Critical Univ South Carolina
Priority to US11/721,554 priority Critical patent/US8129199B2/en
Priority to EP05853792A priority patent/EP1825269A4/en
Publication of WO2006065762A2 publication Critical patent/WO2006065762A2/en
Publication of WO2006065762A3 publication Critical patent/WO2006065762A3/en
Priority to US13/026,929 priority patent/US8241922B2/en
Priority to US13/026,946 priority patent/US20110184202A1/en

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Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/551Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being inorganic
    • G01N33/553Metal or metal coated
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y30/00Nanotechnology for materials or surface science, e.g. nanocomposites
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/65Raman scattering
    • G01N21/658Raman scattering enhancement Raman, e.g. surface plasmons
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366Apparatus specially adapted for solid-phase testing
    • G01N33/54373Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2610/00Assays involving self-assembled monolayers [SAMs]
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00Chemistry: analytical and immunological testing
    • Y10S436/805Optical property
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00Stock material or miscellaneous articles
    • Y10T428/25Web or sheet containing structurally defined element or component and including a second component containing structurally defined particles
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00Stock material or miscellaneous articles
    • Y10T428/29Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982Particulate matter [e.g., sphere, flake, etc.]
    • Y10T428/2991Coated

Abstract

In one aspect, the invention relates to methods for enhancing a Raman signal comprising the steps of providing a sample comprising a metal surface, an analyte adhered to the surface, and a metallic nanoparticle coupled to the surface, wherein the nanoparticle has a plasmon resonance band; exposing the sample to incident energy of an excitation wavelength; and detecting the Raman signal of the analyte. In a further aspect, the invention relates to a composition comprising a metal surface, a functionalized self-assembled monolayer adhered to the surface, wherein the self-assembled monolayer comprises an analyte, and a cetyltrialkylammonium halide-capped metallic nanoparticle coupled to the surface. In a further aspect, the invention relates to a cetyltrimethylammonium bromide-capped gold nanoparticle and a method for preparing same. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
PCT/US2005/044963 2004-12-13 2005-12-13 Surface enhanced raman spectroscopy using shaped gold nanoparticles WO2006065762A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
US11/721,554 US8129199B2 (en) 2004-12-13 2005-12-13 Surface enhanced Raman spectroscopy using shaped gold nanoparticles
EP05853792A EP1825269A4 (en) 2004-12-13 2005-12-13 Surface enhanced raman spectroscopy using shaped gold nanoparticles
US13/026,929 US8241922B2 (en) 2004-12-13 2011-02-14 Surface enhanced Raman spectroscopy using shaped gold nanoparticles
US13/026,946 US20110184202A1 (en) 2004-12-13 2011-02-14 Surface enhanced raman spectroscopy using shaped gold nanoparticles

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US63570404P 2004-12-13 2004-12-13
US60/635,704 2004-12-13
US64892005P 2005-02-01 2005-02-01
US60/648,920 2005-02-01

Related Child Applications (3)

Application Number Title Priority Date Filing Date
US11/721,554 A-371-Of-International US8129199B2 (en) 2004-12-13 2005-12-13 Surface enhanced Raman spectroscopy using shaped gold nanoparticles
US13/026,946 Division US20110184202A1 (en) 2004-12-13 2011-02-14 Surface enhanced raman spectroscopy using shaped gold nanoparticles
US13/026,929 Division US8241922B2 (en) 2004-12-13 2011-02-14 Surface enhanced Raman spectroscopy using shaped gold nanoparticles

Publications (2)

Publication Number Publication Date
WO2006065762A2 WO2006065762A2 (en) 2006-06-22
WO2006065762A3 true WO2006065762A3 (en) 2007-02-08

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Family Applications (1)

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PCT/US2005/044963 WO2006065762A2 (en) 2004-12-13 2005-12-13 Surface enhanced raman spectroscopy using shaped gold nanoparticles

Country Status (3)

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US (3) US8129199B2 (en)
EP (1) EP1825269A4 (en)
WO (1) WO2006065762A2 (en)

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CN103364392A (en) * 2013-05-08 2013-10-23 集美大学 Analysis and detection method of surface enhanced Raman of benzo (a) pyrene
CN104880452A (en) * 2010-09-06 2015-09-02 米特奇有限公司 Method for producing metal complex quantum crystals
CN107159882A (en) * 2017-04-24 2017-09-15 中国科学院合肥物质科学研究院 Gold and silver core-shell nano thorn and its production and use

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Also Published As

Publication number Publication date
US20110184202A1 (en) 2011-07-28
US20080266555A1 (en) 2008-10-30
US8129199B2 (en) 2012-03-06
EP1825269A4 (en) 2012-06-06
WO2006065762A2 (en) 2006-06-22
EP1825269A2 (en) 2007-08-29
US8241922B2 (en) 2012-08-14
US20110137062A1 (en) 2011-06-09

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