WO2006104410A1

WO2006104410A1 - Autogemotransfuser

Info

Publication number: WO2006104410A1
Application number: PCT/RU2005/000468
Authority: WO
Inventors: Renat Suleymanovich Akchurin; Guenrikh Iosifovich Roizenblit; Vladislav Viktorovich Fadeev
Original assignee: Renat Suleymanovich Akchurin; Guenrikh Iosifovich Roizenblit; Vladislav Viktorovich Fadeev
Priority date: 2005-03-29
Filing date: 2005-09-16
Publication date: 2006-10-05
Also published as: RU2284194C1

Abstract

The invention relates to medical engineering, in particular to devices for extracting, purifying and returning a blood and a blood-substituting liquid to a patient under intervention or to a donor. The inventive autogemotransfuser comprises a system for extracting a primary blood, containers with physiological and irrigation solutions, a unit for dividing blood into the components thereof consisting of a pump and a centrifuge, a system for returning erythrocytes to the patient and a waste recovery system. Said primary blood extracting system is provided with a primary blood collecting buffer capacity and a device for reducing pressure in said buffer capacity, wherein said pressure reducing device comprises a vacuum unit provided with at least one vacuum pump having a vacuum manifold which is connected to the buffer capacity with the aid of a pipeline provided with a moisture separator arranged therein. Said invention makes it possible to reduce donor blood consumption for a surgery intervention since the inventive autogemotransfuser enabled erythrocytes to be returned to the patient.

Description

AUTOGEMOTRANSFUZER

FIELD OF TECHNOLOGY

The invention relates to medical equipment, in particular to

5 devices for the selection and purification of blood and blood replacement fluid with their return to the body of the patient or donor being operated on.

BACKGROUND OF THE INVENTION

A device is known for extracorporeal blood processing, comprising means for connecting to a patient for blood sampling, a suction pump, a blood filtration unit in which blood is purified using various blood purification methods

(ultrafiltration + hemosorption, plasmophoresis + plasmosorption, plasmophoresis + hemoxygenation) and a purified blood return pump (see, patent of the Russian Federation N ° 2006230, A61M 1/38, 01/30/1994).

15 The known device allows for single-needle and two-needle perfusion and transfusion of blood, plasma, blood-replacing fluids and is successfully used in the selection of blood directly from the patient (donor). This device cannot be used for the treatment of wound blood, as there is a rapid contamination of the membranes

20 in the filtering unit.

Also known is an autohemotransfuser containing one or two centrifuges for dividing blood into components, in particular for isolating red blood cells from the blood, which are then returned to the patient.

The autohemotransfuser also has a blood pump, which

25 can be installed either at the outlet or at the entrance to the centrifuge (see US patent JV ° 6051147, NKI 210/782, MKI A61M 1/38, 04/18/2000).

The possibility of dividing blood into separate components increases the efficiency of using an autohemotransfuser, however, this device is also not intended for the treatment of wound blood. This device is the closest to the claimed. The objective of the present invention is the development of an autohemotransfuser that provides for the purification of wound blood directly during surgery, with its separation into separate components, in particular, the allocation of red blood cells from wound blood with 5 return to their patient (donor). An additional objective of the invention is the development of autohemotransfuser capable of working in standalone mode.

SUMMARY OF THE INVENTION

The stated technical problems are achieved by the fact that in the autohemotransfuser containing a primary blood sampling system, containers with physiological and flushing solutions, a blood separation unit comprising a pump and a centrifuge, a red blood cell return system to a patient, and a waste disposal system, according to the invention, a system primary blood sampling is equipped with a 15 buffer tank for collecting primary blood and a device for creating a reduced pressure in the buffer tank, which includes a vacuum unit, are equipped with at least one vacuum pump, with a vacuum manifold connected to the buffer tank by a line in which a dehumidifier is installed.

20 Preferably, the red blood cell return system of the patient is equipped with a cumulative red blood cell storage capacity.

Preferably, the pump is reversible and, on the one hand, is connected to a centrifuge, and, on the other hand, tanks with flushing are connected to the pump through overlapping devices

25 solution, a buffer capacity for the collection of primary blood and storage capacity for the storage of red blood cells.

Preferably, the autohemotransfuser is equipped with an additional red blood cell return pump to the patient.

In addition, the autohemotransfuser is equipped with a system for regulating the pressure in the vacuum manifold, which includes a pressure sensor, an electrically controlled normally closed vacuum relief valve in the vacuum manifold; and at least one electrically controlled normally closed vacuum valve for regulating the vacuum level in the vacuum manifold. Preferably, the vacuum unit is equipped with two vacuum pumps, each of which is connected to the vacuum manifold through its electrically operated normally closed vacuum valve for controlling the level of vacuum in the vacuum manifold.

At the same time, the autohemotransfuser is equipped with an autonomous power supply.

Equipping the primary blood sampling system with a buffer tank for collecting primary blood and a device for creating a reduced pressure in the buffer tank, which includes a vacuum unit equipped with at least one vacuum pump, with a vacuum manifold connected to the buffer tank by a line in which a dehumidifier is installed , ensures the non-pressure collection of wound blood of the patient, it does not matter whether only blood is sucked in, or blood mixed with air and foreign particles, since in the buffer tank It is always possible to organize blood purification from foreign particles and air, and the required vacuum level is easily regulated by a vacuum unit, the uninterrupted operation of which is guaranteed by the presence of a moisture separator.

Equipping the erythrocyte return system with a cumulative erythrocyte storage capacity allows the autohemotransfuser to work either in the mode of erythrocyte gradual return during the entire operation, or in the portioned red blood cell return, including with a one-time red blood cell return at the end of the operation.

The implementation of the pump reversible with the claimed connection scheme allows you to do with one pump, which reduces the weight of the autohemotransfuser, its energy consumption and makes it possible to perform it in the form of a stand-alone device, for example, on a mobile trolley.

The presence of an additional red blood cell return pump allows the patient to speed up the red blood cell return procedure, especially if 5 is performed at the end of the operation.

Equipping the auto-hemotransfuser with a vacuum manifold pressure control system, including a pressure sensor, an electrically controlled normally closed vacuum relief valve in the vacuum manifold, and at least one electrically controlled normally closed vacuum regulating valve of the vacuum level in the vacuum manifold, ensures the operation of the auto hemotransfuser.

Equipping a vacuum unit with two vacuum pumps, each of which is connected to a vacuum manifold through its own

15 an electrically controlled normally closed vacuum valve for regulating the vacuum level in the vacuum manifold, increases the reliability of the autohemotransfuser, especially when it is working in stand-alone mode.

Equipping the autohemotransfuser with an autonomous power supply allows it to be used in mobile operating rooms. 20 The technical result from the use of this invention is to reduce the need for donated blood during surgery, since the autohemotransfuser allows you to return to the patient the most valuable part of the blood - red blood cells.

BRIEF DESCRIPTION OF THE DRAWINGS

25 Fig. 1 and 2 show a block diagram of two examples of the implementation of the proposed autohemotransfuser.

BEST MODE FOR CARRYING OUT THE INVENTION The basis of an autohemotransfuser is a blood separation unit comprising a centrifuge 1 and a reversible peristaltic pump 2. connected to the centrifuge, In a pipeline, connecting the pump 2 to the centrifuge, an ultrasonic sensor 3 for controlling blood flow is installed.

The primary blood sampling system includes a buffer tank 4, to which are attached a suction pipe 5 for collecting primary (wound) blood, a pipe 6 for supplying primary blood to the reversing pump 2 and a vacuum pipe 7 for creating a reduced pressure in the buffer tank. The device includes a vacuum unit having a main 8 and backup 9 vacuum pumps, a vacuum manifold 10, a moisture separator 11, and a filter 12. Each of the vacuum pumps is connected to a vacuum manifold through one of two electrically controlled normally closed rarefaction level control valves 13 and 14 in vacuum manifold 10. The vacuum unit is equipped with a pressure sensor 15, which measures the level of vacuum in the vacuum manifold, and is electrically controlled by a normally closed valve to reset the vacuum in the vacuum collector Ore. The pressure sensor 15 and the electrically controlled normally closed valves 13, 14 and 15 form a pressure control system in the vacuum manifold. A container 17 with an anticoagulating saline solution (e.g., heparin) is connected to the suction pipe 5. The pipeline 6 is connected to the reversing pump 2 through a blocking device 18 and a branch 19.

The erythrocyte return system is equipped with a red blood cell storage tank 20, which has at least two pipelines 21 and 22. Pipeline 21 is connected to the reversing pump 2 through a blocking device 23 and junction 19. The red blood cells are returned to the patient through pipeline 22.

Tanks 24 with flushing solution using a pipe 25, a blocking device 26 and a branch 19 are connected to the reversing pump 2. The autohemotransfuser has a waste disposal system including a bag 27 for waste.

In the embodiment of the utility model shown in FIG. 2, the autohemotransfuser is equipped with an additional pump 28 for returning 5 red blood cells to the patient included in the pipeline 22.

The autohemotransfuser has its own autonomous power supply 29, as shown in Fig.2. This power supply circuit is preferred, but not the only one, and it is possible to connect an autohemotransfuser to a conventional power network. ιо The autohemotransfuser has reusable equipment, which includes all power units, in particular, a centrifuge 1, a reversible pump 2, an additional pump 28, devices that are part of a vacuum unit and an autonomous power supply 29. All elements of the primary blood sampling system (buffer

15 capacity 4, pipelines 5, 6 and 7), red blood cell return systems to the patient (storage tank 20, pipelines 21 and 22), capacity 24 with flushing solution, capacity 17 with physiological saline, pipelines 25 and junction 19 are disposable and must be completely replaced after operation.

20 To bring the auto-hemotransfuser into operation, start the vacuum pumps 8 and 9 and bring the vacuum unit to stationary operation with a steady vacuum level in the vacuum manifold 10. Connect to the pump 2 a primary blood sampling system, a red blood cell return system to the patient, capacities of 17 and 24 s

25 physiological and flushing solutions and a bag 27 for collecting waste. The buffer tank 4 is additionally attached to the vacuum unit. The open end of the pipeline 5 is placed in spilled wound blood. Under the action of reduced pressure, wound blood through pipeline 5 enters the buffer tank 4 and from there through the pipeline zo 6 is pumped by pump 2 to the centrifuge 1. In the centrifuge, red blood cells separated from the blood and accumulate in it. The remaining mass of blood is dumped into the bag 27 for waste. According to the accumulation of a portion of red blood cells, the flow of wound blood stops (device 18 is blocked) and a washing solution from tanks 24 is fed to pump 2 and centrifuge 1. After washing, washed (clean) red blood cells by pump 2 are piped through pipeline 21 to the red blood cell storage tank 20, whence Needs are returned via pipeline 22 to the patient either by gravity, as shown in FIG. 1, or by means of a pump 28, as shown in FIG. 2. INDUSTRIAL APPLICABILITY

The claimed autohemotransfuser can be manufactured industrially using known blood compatible materials. When implementing the invention, various peristaltic pumps and centrifuges can be used, as well as various vacuum pumps, the number of which may differ from the number of pumps shown in the figures, without departing from the spirit and scope of the present invention, determined by the scope of the claims set forth in the claims.

Claims

CLAIM

1. An autohemotransfuser containing a primary blood sampling system, containers with physiological and flushing solutions, a blood separation unit comprising a pump and a centrifuge, a red blood cell return system to a patient, and a waste disposal system, characterized in that the primary blood sampling system is equipped with a buffer tank collection of primary blood and a device for creating a reduced pressure in the buffer tank, including a vacuum unit equipped with at least one vacuum pump with a vacuum a lecturer connected to the buffer tank by a line in which a moisture separator is installed.

2. Autohemotransfuser according to claim 1, characterized in that the red blood cell return system to the patient is equipped with an accumulative capacity for storing red blood cells.

3. The autohemotransfuser according to claim 2, characterized in that the pump is reversible and is connected to a centrifuge on the one hand, and tanks with flushing solution, a buffer tank for collecting primary blood and an accumulative capacity for storing red blood cells are connected to the pump through overlapping devices.

4. Autohemotransfuser according to claim 3, characterized in that it is equipped with an additional red blood cell return pump to the patient.

5. The autohemotransfuser according to claim 1, characterized in that it is equipped with a pressure control system in the vacuum manifold, including a pressure sensor, an electrically controlled normally closed vacuum relief valve in the vacuum manifold, and at least one electrically controlled normally closed regulation valve vacuum level in the vacuum manifold.

6. Autohemotransfuser according to claim 5, characterized in that the vacuum unit is equipped with two vacuum pumps, each of which is connected to the vacuum manifold through its own electrically controlled normally closed valve for regulating the vacuum level in the vacuum manifold.

7. Autohemotransfuser according to claim 1, characterized in that it is equipped with an autonomous power supply.