WO2006110843A3 - Engineered deremal tissue particles and transplantation methods - Google Patents

Engineered deremal tissue particles and transplantation methods Download PDF

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Publication number
WO2006110843A3
WO2006110843A3 PCT/US2006/013712 US2006013712W WO2006110843A3 WO 2006110843 A3 WO2006110843 A3 WO 2006110843A3 US 2006013712 W US2006013712 W US 2006013712W WO 2006110843 A3 WO2006110843 A3 WO 2006110843A3
Authority
WO
WIPO (PCT)
Prior art keywords
engineered
deremal
particles
tissue particles
transplantation methods
Prior art date
Application number
PCT/US2006/013712
Other languages
French (fr)
Other versions
WO2006110843A2 (en
Inventor
Elof Eriksson
W Robert Allison
Christian Baker
Original Assignee
Applied Tissue Technologies Ll
Elof Eriksson
W Robert Allison
Christian Baker
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Applied Tissue Technologies Ll, Elof Eriksson, W Robert Allison, Christian Baker filed Critical Applied Tissue Technologies Ll
Publication of WO2006110843A2 publication Critical patent/WO2006110843A2/en
Publication of WO2006110843A3 publication Critical patent/WO2006110843A3/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3604Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
    • A61L27/362Skin, e.g. dermal papillae
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3804Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3839Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by the site of application in the body
    • A61L27/3869Epithelial tissues other than skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/60Materials for use in artificial skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Abstract

The invention relates to a novel method for introducing a biological substance into a human or non-human subject. The method generally involves harvesting dermal tissue; processing the tissue into dermal particles; genetically engineering a plurality of dermal cells of the particles; and transplanting the engineered particles to a receiving site on the subject to facilitate therapeutic treatment.
PCT/US2006/013712 2005-04-12 2006-04-12 Engineered deremal tissue particles and transplantation methods WO2006110843A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US67059205P 2005-04-12 2005-04-12
US60/670,592 2005-04-12

Publications (2)

Publication Number Publication Date
WO2006110843A2 WO2006110843A2 (en) 2006-10-19
WO2006110843A3 true WO2006110843A3 (en) 2007-02-22

Family

ID=37087684

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2006/013712 WO2006110843A2 (en) 2005-04-12 2006-04-12 Engineered deremal tissue particles and transplantation methods

Country Status (1)

Country Link
WO (1) WO2006110843A2 (en)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9107896B2 (en) 2001-11-05 2015-08-18 Medgenics Medical Israel Ltd. Dermal micro-organs, methods and apparatuses for producing and using the same
US9127084B2 (en) 2006-09-14 2015-09-08 Medgenics Medical Israel Ltd. Long lasting drug formulations
US9155749B2 (en) 2006-09-14 2015-10-13 Medgenics Medical Israel Ltd. Long lasting drug formulations
US9468667B2 (en) 2001-11-05 2016-10-18 Medgenics Medical Israel Ltd. Dermal micro-organs, methods and apparatuses for producing and using the same

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8088568B2 (en) 2001-11-05 2012-01-03 Medgentics, Inc. Dermal micro-organs, methods and apparatuses for producing and using the same
AU2004236678B2 (en) 2003-05-01 2010-05-20 Medgenics Inc. Dermal micro organs, methods and apparatuses for producing and using the same
US8454948B2 (en) 2006-09-14 2013-06-04 Medgenics Medical Israel Ltd. Long lasting drug formulations

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2018517A (en) * 1933-04-01 1935-10-22 Fetter Edward Elastic adhesive bandage
US5152757A (en) * 1989-12-14 1992-10-06 Brigham And Women's Hospital System for diagnosis and treatment of wounds
US20030124565A1 (en) * 2001-07-09 2003-07-03 Garfinkel Leonard I. Efficient methods for assessing and validating ecandidate protein-based therapeutic molecules encoded by nucleic acid sequences of interest

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2018517A (en) * 1933-04-01 1935-10-22 Fetter Edward Elastic adhesive bandage
US5152757A (en) * 1989-12-14 1992-10-06 Brigham And Women's Hospital System for diagnosis and treatment of wounds
US20030124565A1 (en) * 2001-07-09 2003-07-03 Garfinkel Leonard I. Efficient methods for assessing and validating ecandidate protein-based therapeutic molecules encoded by nucleic acid sequences of interest

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
CHANG P.L. ET AL.: "Development of engineered cells for implantation in gene therapy", ADVANCED DRUG DELIVERY REVIEWS, vol. 33, 1998, pages 31 - 43, XP003008537 *

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9107896B2 (en) 2001-11-05 2015-08-18 Medgenics Medical Israel Ltd. Dermal micro-organs, methods and apparatuses for producing and using the same
US9468667B2 (en) 2001-11-05 2016-10-18 Medgenics Medical Israel Ltd. Dermal micro-organs, methods and apparatuses for producing and using the same
US9127084B2 (en) 2006-09-14 2015-09-08 Medgenics Medical Israel Ltd. Long lasting drug formulations
US9155749B2 (en) 2006-09-14 2015-10-13 Medgenics Medical Israel Ltd. Long lasting drug formulations

Also Published As

Publication number Publication date
WO2006110843A2 (en) 2006-10-19

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