WO2006110843A3 - Engineered deremal tissue particles and transplantation methods - Google Patents
Engineered deremal tissue particles and transplantation methods Download PDFInfo
- Publication number
- WO2006110843A3 WO2006110843A3 PCT/US2006/013712 US2006013712W WO2006110843A3 WO 2006110843 A3 WO2006110843 A3 WO 2006110843A3 US 2006013712 W US2006013712 W US 2006013712W WO 2006110843 A3 WO2006110843 A3 WO 2006110843A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- engineered
- deremal
- particles
- tissue particles
- transplantation methods
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
- A61L27/362—Skin, e.g. dermal papillae
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3839—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by the site of application in the body
- A61L27/3869—Epithelial tissues other than skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/60—Materials for use in artificial skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
Abstract
The invention relates to a novel method for introducing a biological substance into a human or non-human subject. The method generally involves harvesting dermal tissue; processing the tissue into dermal particles; genetically engineering a plurality of dermal cells of the particles; and transplanting the engineered particles to a receiving site on the subject to facilitate therapeutic treatment.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US67059205P | 2005-04-12 | 2005-04-12 | |
US60/670,592 | 2005-04-12 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2006110843A2 WO2006110843A2 (en) | 2006-10-19 |
WO2006110843A3 true WO2006110843A3 (en) | 2007-02-22 |
Family
ID=37087684
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2006/013712 WO2006110843A2 (en) | 2005-04-12 | 2006-04-12 | Engineered deremal tissue particles and transplantation methods |
Country Status (1)
Country | Link |
---|---|
WO (1) | WO2006110843A2 (en) |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9107896B2 (en) | 2001-11-05 | 2015-08-18 | Medgenics Medical Israel Ltd. | Dermal micro-organs, methods and apparatuses for producing and using the same |
US9127084B2 (en) | 2006-09-14 | 2015-09-08 | Medgenics Medical Israel Ltd. | Long lasting drug formulations |
US9155749B2 (en) | 2006-09-14 | 2015-10-13 | Medgenics Medical Israel Ltd. | Long lasting drug formulations |
US9468667B2 (en) | 2001-11-05 | 2016-10-18 | Medgenics Medical Israel Ltd. | Dermal micro-organs, methods and apparatuses for producing and using the same |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8088568B2 (en) | 2001-11-05 | 2012-01-03 | Medgentics, Inc. | Dermal micro-organs, methods and apparatuses for producing and using the same |
AU2004236678B2 (en) | 2003-05-01 | 2010-05-20 | Medgenics Inc. | Dermal micro organs, methods and apparatuses for producing and using the same |
US8454948B2 (en) | 2006-09-14 | 2013-06-04 | Medgenics Medical Israel Ltd. | Long lasting drug formulations |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2018517A (en) * | 1933-04-01 | 1935-10-22 | Fetter Edward | Elastic adhesive bandage |
US5152757A (en) * | 1989-12-14 | 1992-10-06 | Brigham And Women's Hospital | System for diagnosis and treatment of wounds |
US20030124565A1 (en) * | 2001-07-09 | 2003-07-03 | Garfinkel Leonard I. | Efficient methods for assessing and validating ecandidate protein-based therapeutic molecules encoded by nucleic acid sequences of interest |
-
2006
- 2006-04-12 WO PCT/US2006/013712 patent/WO2006110843A2/en active Application Filing
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2018517A (en) * | 1933-04-01 | 1935-10-22 | Fetter Edward | Elastic adhesive bandage |
US5152757A (en) * | 1989-12-14 | 1992-10-06 | Brigham And Women's Hospital | System for diagnosis and treatment of wounds |
US20030124565A1 (en) * | 2001-07-09 | 2003-07-03 | Garfinkel Leonard I. | Efficient methods for assessing and validating ecandidate protein-based therapeutic molecules encoded by nucleic acid sequences of interest |
Non-Patent Citations (1)
Title |
---|
CHANG P.L. ET AL.: "Development of engineered cells for implantation in gene therapy", ADVANCED DRUG DELIVERY REVIEWS, vol. 33, 1998, pages 31 - 43, XP003008537 * |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9107896B2 (en) | 2001-11-05 | 2015-08-18 | Medgenics Medical Israel Ltd. | Dermal micro-organs, methods and apparatuses for producing and using the same |
US9468667B2 (en) | 2001-11-05 | 2016-10-18 | Medgenics Medical Israel Ltd. | Dermal micro-organs, methods and apparatuses for producing and using the same |
US9127084B2 (en) | 2006-09-14 | 2015-09-08 | Medgenics Medical Israel Ltd. | Long lasting drug formulations |
US9155749B2 (en) | 2006-09-14 | 2015-10-13 | Medgenics Medical Israel Ltd. | Long lasting drug formulations |
Also Published As
Publication number | Publication date |
---|---|
WO2006110843A2 (en) | 2006-10-19 |
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