WO2006113631A3 - Bioenhanced compositions - Google Patents
Bioenhanced compositions Download PDFInfo
- Publication number
- WO2006113631A3 WO2006113631A3 PCT/US2006/014422 US2006014422W WO2006113631A3 WO 2006113631 A3 WO2006113631 A3 WO 2006113631A3 US 2006014422 W US2006014422 W US 2006014422W WO 2006113631 A3 WO2006113631 A3 WO 2006113631A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- arb
- composition
- solubility
- solubility enhancing
- present
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4866—Organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Cardiology (AREA)
- Neurosurgery (AREA)
- Heart & Thoracic Surgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Hospice & Palliative Care (AREA)
- Biophysics (AREA)
- Psychiatry (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Pain & Pain Management (AREA)
- Dermatology (AREA)
- Inorganic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Priority Applications (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2008507777A JP2008536929A (en) | 2005-04-18 | 2006-04-18 | Bio-enhancing composition |
CA002605183A CA2605183A1 (en) | 2005-04-18 | 2006-04-18 | Bioenhanced compositions |
AU2006236497A AU2006236497A1 (en) | 2005-04-18 | 2006-04-18 | Bioenhanced compositions |
MX2007012947A MX2007012947A (en) | 2005-04-18 | 2006-04-18 | Bioenhanced compositions. |
EP06750455A EP1877042A4 (en) | 2005-04-18 | 2006-04-18 | Bioenhanced compositions |
IL186721A IL186721A0 (en) | 2005-04-18 | 2007-10-17 | Bioenhanced compositions |
US12/557,181 US20100119607A1 (en) | 2005-04-18 | 2009-09-10 | Bioenhanced compositions |
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IN477MU2005 | 2005-04-18 | ||
IN477/MUM/2005 | 2005-04-18 | ||
IN315MU2006 | 2006-03-06 | ||
IN0315/MUM/2006 | 2006-03-06 |
Related Child Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US11918728 A-371-Of-International | 2006-04-18 | ||
US12/557,181 Continuation US20100119607A1 (en) | 2005-04-18 | 2009-09-10 | Bioenhanced compositions |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2006113631A2 WO2006113631A2 (en) | 2006-10-26 |
WO2006113631A3 true WO2006113631A3 (en) | 2006-12-14 |
Family
ID=37115820
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2006/014422 WO2006113631A2 (en) | 2005-04-18 | 2006-04-18 | Bioenhanced compositions |
Country Status (8)
Country | Link |
---|---|
EP (1) | EP1877042A4 (en) |
JP (1) | JP2008536929A (en) |
KR (1) | KR20080042039A (en) |
AU (1) | AU2006236497A1 (en) |
CA (1) | CA2605183A1 (en) |
IL (1) | IL186721A0 (en) |
MX (1) | MX2007012947A (en) |
WO (1) | WO2006113631A2 (en) |
Families Citing this family (32)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20090123543A1 (en) * | 2006-01-02 | 2009-05-14 | Rubicon Research Private Limited | Pharmaceutical compositions |
JP2010502698A (en) * | 2006-09-05 | 2010-01-28 | アストラゼネカ アクチボラグ | Pharmaceutical composition comprising candesartan cilexetil |
JP5439182B2 (en) * | 2006-10-20 | 2014-03-12 | アボツト・ヘルスケア・プロダクツ・ベー・ブイ | Chemical micelle nanoparticles |
US7923026B2 (en) | 2006-10-20 | 2011-04-12 | Solvay Pharmaceuticals B.V. | Embedded micellar nanoparticles |
WO2008064338A2 (en) * | 2006-11-22 | 2008-05-29 | Rubicon Research Pvt. Ltd. | Valsartan formulation for pulsatile delivery |
WO2008065097A2 (en) * | 2006-11-28 | 2008-06-05 | Laboratorios Liconsa, S.A. | Stabilized solid pharmaceutical composition of candesartan cilexetil |
MX2009005947A (en) * | 2006-12-05 | 2009-06-17 | Novartis Ag | Microemulsion dosage forms of valsartan and methods of making the same. |
US20080152717A1 (en) * | 2006-12-14 | 2008-06-26 | Isp Investments, Inc. | Amorphous valsartan and the production thereof |
WO2008084504A2 (en) * | 2007-01-12 | 2008-07-17 | Rubicon Research Private Limited | Pharmaceutical compositions of angiotensin ii receptor blockers |
RU2009141539A (en) * | 2007-04-25 | 2011-05-27 | Тева Фармасьютикал Индастриес Лтд. (Il) | COMPLEX OF PHARMACEUTICAL FILLER |
WO2008149338A2 (en) * | 2007-06-06 | 2008-12-11 | Dexcel Ltd. | Process for forming solid oral dosage forms of angiotensin ii receptor antagonists |
WO2009017812A2 (en) * | 2007-08-01 | 2009-02-05 | Teva Pharmaceutical Industries Ltd. | Pharmaceutical composition of candesartan |
JP2011500577A (en) * | 2007-10-09 | 2011-01-06 | ノバルティス アーゲー | Pharmaceutical formulation of valsartan |
UA100866C2 (en) * | 2007-10-19 | 2013-02-11 | Эбботт Гмбх Унд Ко. Кг | Solid dispersion product comprising n-aryl urea-based compounds |
JP5222550B2 (en) * | 2007-12-27 | 2013-06-26 | 財團法人工業技術研究院 | Sustained release composition and method for producing the same |
WO2009084040A1 (en) * | 2007-12-28 | 2009-07-09 | Rubicon Research Private Limited | Once a day formulation of angiotensin receptor blockers |
CN101951902A (en) * | 2008-02-28 | 2011-01-19 | 诺瓦提斯公司 | Valsartan solid oral dosage forms and methods of making such formulations |
BRPI0913337A2 (en) * | 2008-06-03 | 2017-05-23 | Novartis Ag | pulsatile release of valsartan |
SI2165702T1 (en) | 2008-09-17 | 2012-05-31 | Helm Ag | Stable and readily dissolved compositions of candesartan cilexetil prepared with wet granulation |
DE102008047910A1 (en) | 2008-09-19 | 2010-03-25 | Molkerei Meggle Wasserburg Gmbh & Co. Kg | Tabletting excipient based on lactose and cellulose |
KR101817986B1 (en) * | 2009-06-25 | 2018-01-16 | 진양제약주식회사 | Pharmaceutical composition containing carboxylosartan and a production method therefor |
WO2011028016A2 (en) * | 2009-09-04 | 2011-03-10 | 한올바이오파마주식회사 | Pharmaceutical preparation comprising beta-adrenergic blockers and angiotensin ii receptor blockers |
CA2864088C (en) * | 2012-02-08 | 2020-04-28 | Supernus Pharmaceuticals, Inc. | Modified release formulations of viloxazine |
JP6272328B2 (en) * | 2012-12-05 | 2018-01-31 | 沢井製薬株式会社 | Candesartan cilexetil-containing preparation |
WO2014119667A1 (en) | 2013-01-30 | 2014-08-07 | 沢井製薬株式会社 | Pharmaceutical composition containing candesartan cilexetil |
WO2016005994A2 (en) * | 2014-07-06 | 2016-01-14 | Gattefosse India Pvt. Ltd. | Pharmaceutical composition comprising solid dispersion of bcs class ii drugs with gelucires |
US9675585B1 (en) | 2016-03-24 | 2017-06-13 | Ezra Pharma | Extended release pharmaceutical formulations |
US9687475B1 (en) | 2016-03-24 | 2017-06-27 | Ezra Pharma Llc | Extended release pharmaceutical formulations with controlled impurity levels |
WO2019070845A1 (en) | 2017-10-04 | 2019-04-11 | Celgene Corporation | Compositions and methods of use of cis-4-[2-{[(3s,4r)-3-fluorooxan-4-yl] amino}-8-(2,4,6-trichloroanilino)-9h-purin-9-yl]-1-methylcyclohexane-1-carboxamide |
CN109350609A (en) * | 2018-11-14 | 2019-02-19 | 常州大学 | A kind of preparation of chitosan package zeins nanoparticle and the application for loading acacetin sodium salt |
CN113933472A (en) * | 2020-06-29 | 2022-01-14 | 武汉武药科技有限公司 | Dissolution medium for determining dissolution rate of telmisartan solid preparation and application thereof |
CN112516105A (en) * | 2020-12-10 | 2021-03-19 | 成都恒瑞制药有限公司 | Losartan potassium oral preparation and preparation method thereof |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6248363B1 (en) * | 1999-11-23 | 2001-06-19 | Lipocine, Inc. | Solid carriers for improved delivery of active ingredients in pharmaceutical compositions |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20030236236A1 (en) * | 1999-06-30 | 2003-12-25 | Feng-Jing Chen | Pharmaceutical compositions and dosage forms for administration of hydrophobic drugs |
US20030180352A1 (en) * | 1999-11-23 | 2003-09-25 | Patel Mahesh V. | Solid carriers for improved delivery of active ingredients in pharmaceutical compositions |
US20030152622A1 (en) * | 2001-10-25 | 2003-08-14 | Jenny Louie-Helm | Formulation of an erodible, gastric retentive oral diuretic |
JP3751287B2 (en) * | 2002-03-27 | 2006-03-01 | バイエル薬品株式会社 | Miniaturized nifedipine nucleated tablets |
AU2003294883A1 (en) * | 2002-12-18 | 2004-07-09 | Novartis Ag | Combinations of valsartan with cox-2 inhibitors |
US20050096365A1 (en) * | 2003-11-03 | 2005-05-05 | David Fikstad | Pharmaceutical compositions with synchronized solubilizer release |
HRP20031029A2 (en) * | 2003-12-12 | 2005-08-31 | Belupo - Lijekovi I Kozmetika D.D. | Process for production of inclusion complexes of valsartan with?-cylodextrin |
-
2006
- 2006-04-18 EP EP06750455A patent/EP1877042A4/en not_active Withdrawn
- 2006-04-18 MX MX2007012947A patent/MX2007012947A/en unknown
- 2006-04-18 JP JP2008507777A patent/JP2008536929A/en active Pending
- 2006-04-18 AU AU2006236497A patent/AU2006236497A1/en not_active Abandoned
- 2006-04-18 CA CA002605183A patent/CA2605183A1/en not_active Abandoned
- 2006-04-18 KR KR1020077026647A patent/KR20080042039A/en not_active Application Discontinuation
- 2006-04-18 WO PCT/US2006/014422 patent/WO2006113631A2/en active Application Filing
-
2007
- 2007-10-17 IL IL186721A patent/IL186721A0/en unknown
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6248363B1 (en) * | 1999-11-23 | 2001-06-19 | Lipocine, Inc. | Solid carriers for improved delivery of active ingredients in pharmaceutical compositions |
Also Published As
Publication number | Publication date |
---|---|
AU2006236497A1 (en) | 2006-10-26 |
JP2008536929A (en) | 2008-09-11 |
EP1877042A4 (en) | 2011-03-02 |
KR20080042039A (en) | 2008-05-14 |
CA2605183A1 (en) | 2006-10-26 |
EP1877042A2 (en) | 2008-01-16 |
WO2006113631A2 (en) | 2006-10-26 |
MX2007012947A (en) | 2008-04-09 |
IL186721A0 (en) | 2008-02-09 |
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