WO2006115938A3 - Method and apparatus for separation of particles suspended in a fluid - Google Patents
Method and apparatus for separation of particles suspended in a fluid Download PDFInfo
- Publication number
- WO2006115938A3 WO2006115938A3 PCT/US2006/014756 US2006014756W WO2006115938A3 WO 2006115938 A3 WO2006115938 A3 WO 2006115938A3 US 2006014756 W US2006014756 W US 2006014756W WO 2006115938 A3 WO2006115938 A3 WO 2006115938A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- particles
- separation
- particle
- fluid
- separation stages
- Prior art date
Links
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
- B04B—CENTRIFUGES
- B04B5/00—Other centrifuges
- B04B5/04—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers
- B04B5/0442—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3693—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits using separation based on different densities of components, e.g. centrifuging
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3693—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits using separation based on different densities of components, e.g. centrifuging
- A61M1/3696—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits using separation based on different densities of components, e.g. centrifuging with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D21/00—Separation of suspended solid particles from liquids by sedimentation
- B01D21/24—Feed or discharge mechanisms for settling tanks
- B01D21/245—Discharge mechanisms for the sediments
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D21/00—Separation of suspended solid particles from liquids by sedimentation
- B01D21/26—Separation of sediment aided by centrifugal force or centripetal force
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D21/00—Separation of suspended solid particles from liquids by sedimentation
- B01D21/26—Separation of sediment aided by centrifugal force or centripetal force
- B01D21/262—Separation of sediment aided by centrifugal force or centripetal force by using a centrifuge
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D21/00—Separation of suspended solid particles from liquids by sedimentation
- B01D21/30—Control equipment
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D21/00—Separation of suspended solid particles from liquids by sedimentation
- B01D21/30—Control equipment
- B01D21/32—Density control of clear liquid or sediment, e.g. optical control ; Control of physical properties
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F25/00—Flow mixers; Mixers for falling materials, e.g. solid particles
- B01F25/40—Static mixers
- B01F25/42—Static mixers in which the mixing is affected by moving the components jointly in changing directions, e.g. in tubes provided with baffles or obstructions
- B01F25/43—Mixing tubes, e.g. wherein the material is moved in a radial or partly reversed direction
- B01F25/431—Straight mixing tubes with baffles or obstructions that do not cause substantial pressure drop; Baffles therefor
- B01F25/4317—Profiled elements, e.g. profiled blades, bars, pillars, columns or chevrons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/02—Blood transfusion apparatus
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D2221/00—Applications of separation devices
- B01D2221/10—Separation devices for use in medical, pharmaceutical or laboratory applications, e.g. separating amalgam from dental treatment residues
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F25/00—Flow mixers; Mixers for falling materials, e.g. solid particles
- B01F25/40—Static mixers
- B01F25/42—Static mixers in which the mixing is affected by moving the components jointly in changing directions, e.g. in tubes provided with baffles or obstructions
- B01F25/43—Mixing tubes, e.g. wherein the material is moved in a radial or partly reversed direction
- B01F25/431—Straight mixing tubes with baffles or obstructions that do not cause substantial pressure drop; Baffles therefor
- B01F25/43197—Straight mixing tubes with baffles or obstructions that do not cause substantial pressure drop; Baffles therefor characterised by the mounting of the baffles or obstructions
- B01F25/431971—Mounted on the wall
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
- B04B—CENTRIFUGES
- B04B5/00—Other centrifuges
- B04B5/04—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers
- B04B5/0442—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation
- B04B2005/045—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation having annular separation channels
Abstract
For an effective separation of more than one kind of particle from a mixture, a plurality of separation stages (14, 60, 66, 77, 76) are provided, arranged in series. Mixer elements (28) may be disposed along the flow path to disturb the sedimenting particles, to release entrained lighter particles. Further, the separation channel may widen near the particle recovery port(s) (38) , to well suspend lighter particles in the fluid as denser particles are extracted and/or to allow gravitational forces to more effectively influence particle movement. In an example embodiment one stage utilizes Coriolis force in a narrow, radial passage (60) for concentrating and agglomerating particles. The serial separation stages may be communicated with a radially inward extending passage (56) to limit undesirable particle spill-over.
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP06750729A EP1871507B1 (en) | 2005-04-21 | 2006-04-18 | Method and apparatus for separation of particles suspended in a fluid |
AT06750729T ATE550082T1 (en) | 2005-04-21 | 2006-04-18 | METHOD AND DEVICE FOR SEPARATING PARTICLES SUSPENDED IN A LIQUID |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US11/110,689 | 2005-04-21 | ||
US11/110,689 US7473216B2 (en) | 2005-04-21 | 2005-04-21 | Apparatus for separation of a fluid with a separation channel having a mixer component |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2006115938A2 WO2006115938A2 (en) | 2006-11-02 |
WO2006115938A3 true WO2006115938A3 (en) | 2007-06-14 |
Family
ID=36636902
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2006/014756 WO2006115938A2 (en) | 2005-04-21 | 2006-04-18 | Method and apparatus for separation of particles suspended in a fluid |
Country Status (4)
Country | Link |
---|---|
US (1) | US7473216B2 (en) |
EP (1) | EP1871507B1 (en) |
AT (1) | ATE550082T1 (en) |
WO (1) | WO2006115938A2 (en) |
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US7473216B2 (en) * | 2005-04-21 | 2009-01-06 | Fresenius Hemocare Deutschland Gmbh | Apparatus for separation of a fluid with a separation channel having a mixer component |
EP1795894A1 (en) * | 2005-12-06 | 2007-06-13 | Roche Diagnostics GmbH | Plasma separation on a disk like device |
US9433880B2 (en) * | 2006-11-30 | 2016-09-06 | Palo Alto Research Center Incorporated | Particle separation and concentration system |
US8931644B2 (en) * | 2006-11-30 | 2015-01-13 | Palo Alto Research Center Incorporated | Method and apparatus for splitting fluid flow in a membraneless particle separation system |
US8276760B2 (en) | 2006-11-30 | 2012-10-02 | Palo Alto Research Center Incorporated | Serpentine structures for continuous flow particle separations |
US9862624B2 (en) * | 2007-11-07 | 2018-01-09 | Palo Alto Research Center Incorporated | Device and method for dynamic processing in water purification |
US10052571B2 (en) * | 2007-11-07 | 2018-08-21 | Palo Alto Research Center Incorporated | Fluidic device and method for separation of neutrally buoyant particles |
US9486812B2 (en) * | 2006-11-30 | 2016-11-08 | Palo Alto Research Center Incorporated | Fluidic structures for membraneless particle separation |
US8875903B2 (en) * | 2007-03-19 | 2014-11-04 | Palo Alto Research Center Incorporated | Vortex structure for high throughput continuous flow separation |
US8191715B2 (en) * | 2007-04-02 | 2012-06-05 | Samsung Electronics Co., Ltd. | Centrifugal force-based microfluidic device and microfluidic system including the same |
FR2931079B1 (en) * | 2008-05-13 | 2010-07-30 | Commissariat Energie Atomique | DEVICE AND METHOD FOR SEPARATING A SUSPENSION |
US8647479B2 (en) * | 2009-06-12 | 2014-02-11 | Palo Alto Research Center Incorporated | Stand-alone integrated water treatment system for distributed water supply to small communities |
US20100314323A1 (en) * | 2009-06-12 | 2010-12-16 | Palo Alto Research Center Incorporated | Method and apparatus for continuous flow membrane-less algae dewatering |
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WO2011025756A1 (en) | 2009-08-25 | 2011-03-03 | Agnes Ostafin | Method and apparatus for continuous removal of submicron sized particles in a closed loop liquid flow system |
US10751464B2 (en) | 2009-08-25 | 2020-08-25 | Nanoshell Company, Llc | Therapeutic retrieval of targets in biological fluids |
US10099227B2 (en) | 2009-08-25 | 2018-10-16 | Nanoshell Company, Llc | Method and apparatus for continuous removal of sub-micron sized particles in a closed loop liquid flow system |
US11285494B2 (en) | 2009-08-25 | 2022-03-29 | Nanoshell Company, Llc | Method and apparatus for continuous removal of sub-micron sized particles in a closed loop liquid flow system |
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WO2012055048A1 (en) * | 2010-10-29 | 2012-05-03 | The University Of British Columbia | Methods and apparatus for detecting particles entrained in fluids |
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US10983040B2 (en) | 2013-03-15 | 2021-04-20 | Particles Plus, Inc. | Particle counter with integrated bootloader |
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-
2005
- 2005-04-21 US US11/110,689 patent/US7473216B2/en not_active Expired - Fee Related
-
2006
- 2006-04-18 AT AT06750729T patent/ATE550082T1/en active
- 2006-04-18 WO PCT/US2006/014756 patent/WO2006115938A2/en active Application Filing
- 2006-04-18 EP EP06750729A patent/EP1871507B1/en not_active Not-in-force
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US5954626A (en) * | 1996-05-15 | 1999-09-21 | Cobe Laboratories, Inc. | Method of minimizing coriolis effects in a centrifugal separation channel |
EP1375006A1 (en) * | 1997-05-08 | 2004-01-02 | Gambro, Inc. | Apparatus and method for separation of fluid components |
US20030166445A1 (en) * | 2000-09-05 | 2003-09-04 | Jean-Denis Rochat | Rotatable chamber for separating blood or plasma components |
US20040164032A1 (en) * | 2000-11-02 | 2004-08-26 | Gambro, Inc. | Fluid Separation Methods Using a Fluid Pressure Driven and/or Balanced Approach |
US20040245189A1 (en) * | 2001-06-25 | 2004-12-09 | Mission Medical, Inc. | Integrated automatic blood collection and processing unit |
Non-Patent Citations (1)
Title |
---|
SUGAI M: "FRESENIUS AS.TEC204 BLOOD BELL SEPARATOR", THERAPEUTIC APHERESIS AND DIALYSIS, XX, XX, vol. 7, no. 1, February 2003 (2003-02-01), pages 37 - 43, XP009069496 * |
Also Published As
Publication number | Publication date |
---|---|
EP1871507B1 (en) | 2012-03-21 |
WO2006115938A2 (en) | 2006-11-02 |
ATE550082T1 (en) | 2012-04-15 |
EP1871507A2 (en) | 2008-01-02 |
US7473216B2 (en) | 2009-01-06 |
US20060240964A1 (en) | 2006-10-26 |
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