WO2006119126A3 - Shaped osteochondral grafts and methods of using same - Google Patents

Shaped osteochondral grafts and methods of using same Download PDF

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Publication number
WO2006119126A3
WO2006119126A3 PCT/US2006/016491 US2006016491W WO2006119126A3 WO 2006119126 A3 WO2006119126 A3 WO 2006119126A3 US 2006016491 W US2006016491 W US 2006016491W WO 2006119126 A3 WO2006119126 A3 WO 2006119126A3
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WO
WIPO (PCT)
Prior art keywords
grafts
plug
methods
same
improve stability
Prior art date
Application number
PCT/US2006/016491
Other languages
French (fr)
Other versions
WO2006119126A2 (en
Inventor
William F Mckay
Original Assignee
Warsaw Orthopedic Inc
William F Mckay
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warsaw Orthopedic Inc, William F Mckay filed Critical Warsaw Orthopedic Inc
Priority to JP2008509218A priority Critical patent/JP2008539814A/en
Priority to CA002605719A priority patent/CA2605719A1/en
Priority to AU2006242360A priority patent/AU2006242360A1/en
Priority to EP06758801A priority patent/EP1885292A2/en
Priority to CN2006800146897A priority patent/CN101166485B/en
Publication of WO2006119126A2 publication Critical patent/WO2006119126A2/en
Publication of WO2006119126A3 publication Critical patent/WO2006119126A3/en

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    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2230/00Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2230/0002Two-dimensional shapes, e.g. cross-sections
    • A61F2230/0017Angular shapes
    • A61F2230/0021Angular shapes square
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2230/00Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2230/0002Two-dimensional shapes, e.g. cross-sections
    • A61F2230/0028Shapes in the form of latin or greek characters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2230/00Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2230/0002Two-dimensional shapes, e.g. cross-sections
    • A61F2230/0028Shapes in the form of latin or greek characters
    • A61F2230/005Rosette-shaped, e.g. star-shaped
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2230/00Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2230/0063Three-dimensional shapes
    • A61F2230/0069Three-dimensional shapes cylindrical
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2230/00Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2230/0063Three-dimensional shapes
    • A61F2230/0082Three-dimensional shapes parallelepipedal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2250/00Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2250/0014Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof having different values of a given property or geometrical feature, e.g. mechanical property or material property, at different locations within the same prosthesis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2310/00Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
    • A61F2310/00005The prosthesis being constructed from a particular material
    • A61F2310/00179Ceramics or ceramic-like structures

Abstract

Described are plug grafts and in particular embodiments osteochondral plug grafts and grafting methods which utilize unique plug geometries and cooperative graft/host tissue interfaces to improve stability of grafted plugs within host tissue. Embodiments of the invention include harvested osteochondral or synthetic plug grafts having bore geometries other than circular cylinders and which are implantable in correspondingly prepared host sites to resist rotation and improve stability.
PCT/US2006/016491 2005-04-30 2006-05-01 Shaped osteochondral grafts and methods of using same WO2006119126A2 (en)

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JP2008509218A JP2008539814A (en) 2005-04-30 2006-05-01 Molded osteochondral graft
CA002605719A CA2605719A1 (en) 2005-04-30 2006-05-01 Shaped osteochondral grafts and methods of using same
AU2006242360A AU2006242360A1 (en) 2005-04-30 2006-05-01 Shaped osteochondral grafts and methods of using same
EP06758801A EP1885292A2 (en) 2005-04-30 2006-05-01 Shaped osteochondral grafts and methods of using same
CN2006800146897A CN101166485B (en) 2005-04-30 2006-05-01 Shaped osteochondral grafts and methods of using same

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US11/120,136 US20060247790A1 (en) 2005-04-30 2005-04-30 Shaped osteochondral grafts and methods of using same
US11/120,136 2005-04-30

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WO2006119126A2 WO2006119126A2 (en) 2006-11-09
WO2006119126A3 true WO2006119126A3 (en) 2007-04-12

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AU (1) AU2006242360A1 (en)
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Families Citing this family (60)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8563232B2 (en) 2000-09-12 2013-10-22 Lifenet Health Process for devitalizing soft-tissue engineered medical implants, and devitalized soft-tissue medical implants produced
EP1498089A1 (en) 1999-12-15 2005-01-19 Zimmer GmbH Preparation for repairing cartilage defects or cartilage/bone defects in human or animal joints
US7067123B2 (en) 2003-04-29 2006-06-27 Musculoskeletal Transplant Foundation Glue for cartilage repair
US7901457B2 (en) 2003-05-16 2011-03-08 Musculoskeletal Transplant Foundation Cartilage allograft plug
US7837740B2 (en) 2007-01-24 2010-11-23 Musculoskeletal Transplant Foundation Two piece cancellous construct for cartilage repair
US7815926B2 (en) 2005-07-11 2010-10-19 Musculoskeletal Transplant Foundation Implant for articular cartilage repair
WO2007035778A2 (en) 2005-09-19 2007-03-29 Histogenics Corporation Cell-support matrix and a method for preparation thereof
US8394100B2 (en) * 2005-12-23 2013-03-12 Warsaw Orthopedic, Inc. Surgical apparatus and method for manipulating one or more osteochondral plugs
US7776043B2 (en) * 2006-01-26 2010-08-17 Warsaw Orthopedic, Inc. Osteochondral implant fixation procedure and bone dilator used in same
US7722614B2 (en) * 2006-01-27 2010-05-25 Warsaw Orthopedic, Inc, Osteochondral implant fixation method
US8323642B2 (en) * 2006-12-13 2012-12-04 Depuy Mitek, Inc. Tissue fusion method using collagenase for repair of soft tissue
US8435551B2 (en) 2007-03-06 2013-05-07 Musculoskeletal Transplant Foundation Cancellous construct with support ring for repair of osteochondral defects
US20080262616A1 (en) * 2007-04-18 2008-10-23 Warsaw Orthopedic, Inc. Osteochondral graft and method of use for repairing an articular cartilage defect site
US20080294270A1 (en) * 2007-05-24 2008-11-27 Zimmer Orthobiologics, Inc. Differentially processed tissue and processing methods thereof
US20090024224A1 (en) * 2007-07-16 2009-01-22 Chen Silvia S Implantation of cartilage
DE102007037180A1 (en) 2007-08-07 2009-02-19 Peiker Acustic Gmbh & Co. Kg Wireless tracking and monitoring system
US20090054906A1 (en) * 2007-08-24 2009-02-26 Zimmer Orthobiologics, Inc. Medical device and method for delivering an implant to an anatomical site
US8961571B2 (en) * 2007-11-19 2015-02-24 David Lee Method and apparatus for spinal facet joint fusion using irregularly shaped cortical bone implants
US20090157192A1 (en) * 2007-12-14 2009-06-18 Microdexterity Systems, Inc. Replacement joint
CA2717725A1 (en) 2008-03-05 2009-09-11 Musculoskeletal Transplant Foundation Cancellous constructs, cartilage particles and combinations of cancellous constructs and cartilage particles
US8152846B2 (en) * 2008-03-06 2012-04-10 Musculoskeletal Transplant Foundation Instrumentation and method for repair of meniscus tissue
US8801725B2 (en) 2008-03-10 2014-08-12 Zimmer Orthobiologics, Inc. Instruments and methods used when repairing a defect on a tissue surface
ITMI20080967A1 (en) * 2008-05-23 2009-11-24 Salvatore Longoni METHOD OF DESIGN AND / OR SELECTION OF A PLANT AND / OR IMPLANTABLE MATERIAL IN FABRICS OF THE HUMAN OR ANIMAL BODY AND DEVICE AND / OR MATERIAL SO IT IS OBTAINED
US9289302B2 (en) * 2008-07-28 2016-03-22 Zimmer, Inc. Mosaicplasty constructs
US10610364B2 (en) 2008-12-04 2020-04-07 Subchondral Solutions, Inc. Method for ameliorating joint conditions and diseases and preventing bone hypertrophy
US20100145451A1 (en) 2008-12-04 2010-06-10 Derek Dee Joint support and subchondral support system
US8241298B2 (en) 2009-03-27 2012-08-14 Depuy Mitek, Inc. Methods and devices for delivering and affixing tissue scaffolds
US8308814B2 (en) * 2009-03-27 2012-11-13 Depuy Mitek, Inc. Methods and devices for preparing and implanting tissue scaffolds
JP5457544B2 (en) 2009-03-31 2014-04-02 アイエムディーエス コーポレイション Double bundle ACL repair
KR101754173B1 (en) 2009-07-10 2017-07-05 미룩스 홀딩 에스.에이. Hip joint device and method
JP5678055B2 (en) * 2009-07-10 2015-02-25 ミルックス・ホールディング・エスエイ Hip apparatus and method
KR101903698B1 (en) 2009-07-10 2018-10-02 임플란티카 페이턴트 엘티디. Hip joint device and method
WO2011010463A1 (en) * 2009-07-22 2011-01-27 株式会社ネクスト21 Artificial bone constructing unit and artificial bone constructing system
US9113916B2 (en) 2010-08-31 2015-08-25 Zimmer, Inc. Drill bit for osteochondral drilling with guiding element and uses thereof
US8435305B2 (en) 2010-08-31 2013-05-07 Zimmer, Inc. Osteochondral graft delivery device and uses thereof
US10603049B2 (en) 2011-09-02 2020-03-31 Episurf Ip-Management Ab Implant specific drill bit in surgical kit for cartilage repair
US11000387B2 (en) 2011-09-02 2021-05-11 Episurf Ip-Management Ab Implant for cartilage repair
US8968402B2 (en) 2011-10-18 2015-03-03 Arthrocare Corporation ACL implants, instruments, and methods
WO2013137889A1 (en) * 2012-03-15 2013-09-19 Derek Dee Method and device for ameliorating joint conditions and diseases
US9498334B2 (en) * 2012-03-27 2016-11-22 DePuy Synthes Products, Inc. Glenoid defect-filling component
JP2015517879A (en) * 2012-05-30 2015-06-25 ニューヨーク ユニバーシティ Tissue repair device or scaffold
US9216022B2 (en) 2013-02-15 2015-12-22 Arthrex, Inc. Methods and instruments for forming non-circular cartilage grafts
US9289306B2 (en) * 2013-03-15 2016-03-22 Catalyst Orthopaedics Llc Humeral arthroplasty
EP3620120B1 (en) * 2013-04-15 2021-09-22 Episurf IP Management AB Implant comprising a positioning mark
US9345589B2 (en) * 2013-12-19 2016-05-24 Ilion Medical, Inc. Bone implants for orthopedic procedures and corresponding methods
WO2016004991A1 (en) * 2014-07-09 2016-01-14 Episurf Ip-Management Ab Customized implant for cartilage repair and corresponding method of design
US20170172744A1 (en) 2014-07-09 2017-06-22 Episurf Ip-Management Ab Surgical joint implant and a bone-mountable rig
US10077420B2 (en) 2014-12-02 2018-09-18 Histogenics Corporation Cell and tissue culture container
US10779960B2 (en) * 2015-02-27 2020-09-22 In2Bones Usa, Llc Engineered sterile cartilage allograft implant plug with sterile, specific instrument kit(s)
US9763800B2 (en) * 2015-03-18 2017-09-19 Biomet C. V. Implant configured for hammertoe and small bone fixation
US9579204B2 (en) * 2015-07-10 2017-02-28 Oxford Mestar Limited Surgical implants
BR112018010562B1 (en) 2015-11-25 2023-05-02 Subchondral Solutions, Inc IMPLANTABLE ORTHOPEDIC DEVICE AND KIT TO REPAIR AN ANATOMIC JOINT
US9943414B2 (en) * 2015-12-30 2018-04-17 Wasas, Llc. System and method for non-binding allograft subtalar joint implant
CN105534619A (en) * 2016-01-28 2016-05-04 江苏奥康尼医疗科技发展有限公司 Cartilage repair and compensation prosthesis
WO2018115469A1 (en) 2016-12-22 2018-06-28 Episurf Ip-Management Ab System and method for optimizing an implant position in an anatomical joint
CN109966029A (en) * 2017-12-28 2019-07-05 财团法人工业技术研究院 Repair of cartilage carrier, the operational tool group arranged in pairs or groups and cartilage repair systems
US10786370B2 (en) 2017-12-28 2020-09-29 Industrial Technology Research Institute Cartilage repair implant, auxiliary surgical tool kit and cartilage repair system
WO2019165395A1 (en) * 2018-02-26 2019-08-29 The Board Of Trustees Of The Leland Stanford Junior University Graft for segmental bone defect repair
CA3167757A1 (en) * 2020-01-14 2021-07-22 Musculoskeletal Transplant Foundation Multiple component grafts for treating tissue defects and methods for making and using same
CN111904667A (en) * 2020-09-08 2020-11-10 四川大学 Self-locking segmentation design method for maxillary defect prosthesis

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001039694A2 (en) * 1999-12-03 2001-06-07 University Of Leeds Repair of damaged tissue
US20010039455A1 (en) * 2000-03-14 2001-11-08 Timothy Simon Cartilage repair plug
US20040230303A1 (en) * 2003-05-16 2004-11-18 Gomes Katherine A. Cartilage allograft plug
US20050222687A1 (en) * 2004-04-02 2005-10-06 Gordana Vunjak-Novakovic Cartilage implant assembly and method for implantation

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5013649A (en) * 1986-07-01 1991-05-07 Genetics Institute, Inc. DNA sequences encoding osteoinductive products
US5106748A (en) * 1986-07-01 1992-04-21 Genetics Institute, Inc. Dna sequences encoding 5 proteins
US5108922A (en) * 1986-07-01 1992-04-28 Genetics Institute, Inc. DNA sequences encoding BMP-1 products
US5187076A (en) * 1986-07-01 1993-02-16 Genetics Institute, Inc. DNA sequences encoding BMP-6 proteins
ZA874681B (en) * 1986-07-01 1988-04-27 Genetics Inst Novel osteoinductive factors
US5637480A (en) * 1993-05-12 1997-06-10 Genetics Institute, Inc. DNA molecules encoding bone morphogenetic protein-10
DK0698094T3 (en) * 1993-05-12 2004-05-03 Inst Genetics Llc BMP-11 compositions
ATE319823T1 (en) * 1993-12-07 2006-03-15 Inst Genetics Llc BMP-12, BMP-13 AND TENDON-INDUCING COMPOSITIONS CONTAINING SAME
US20030032963A1 (en) * 2001-10-24 2003-02-13 Kyphon Inc. Devices and methods using an expandable body with internal restraint for compressing cancellous bone
US6080194A (en) * 1995-02-10 2000-06-27 The Hospital For Joint Disease Orthopaedic Institute Multi-stage collagen-based template or implant for use in the repair of cartilage lesions
US5635372A (en) * 1995-05-18 1997-06-03 Genetics Institute, Inc. BMP-15 compositions
US5965403A (en) * 1996-09-18 1999-10-12 Genetics Institute, Inc. Nucleic acids encoding bone morphogenic protein-16 (BMP-16)
US20010016646A1 (en) * 1998-03-20 2001-08-23 David C. Rueger Osteogenic devices and methods of use thereof for repair of endochondral bone, osteochondral and chondral defects
US7087082B2 (en) * 1998-08-03 2006-08-08 Synthes (Usa) Bone implants with central chambers
JPH11274367A (en) * 1998-02-17 1999-10-08 Texas Instr Inc <Ti> Forming of ball grid array package
US6200347B1 (en) * 1999-01-05 2001-03-13 Lifenet Composite bone graft, method of making and using same
US6727224B1 (en) * 1999-02-01 2004-04-27 Genetics Institute, Llc. Methods and compositions for healing and repair of articular cartilage
US6652872B2 (en) * 1999-07-06 2003-11-25 Ramat At Tel Aviv University Ltd. Scaffold formed of tissue treated to eliminate cellular and cytosolic elements
AU2001275746B2 (en) * 2000-07-29 2007-04-26 Smith & Nephew Plc Tissue implant for cartilage repair
CA2422710A1 (en) * 2000-09-19 2002-03-28 Sdgi Holdings, Inc. Osteogenic fusion devices
US6855167B2 (en) * 2001-12-05 2005-02-15 Osteotech, Inc. Spinal intervertebral implant, interconnections for such implant and processes for making
US7488348B2 (en) * 2003-05-16 2009-02-10 Musculoskeletal Transplant Foundation Cartilage allograft plug
US20050065042A1 (en) * 2003-09-22 2005-03-24 Alltrista Zinc Products, L.P., An Indiana Limited Partnership Anti-corrosive engine oil system components
CN1972644B (en) * 2003-11-21 2010-08-25 骨棚国际私人有限公司 Bioabsorbable plug implants and method for bone tissue regeneration
US7776089B2 (en) * 2005-03-04 2010-08-17 Rti Biologics, Inc. Assembled bone-tendon-bone grafts

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001039694A2 (en) * 1999-12-03 2001-06-07 University Of Leeds Repair of damaged tissue
US20010039455A1 (en) * 2000-03-14 2001-11-08 Timothy Simon Cartilage repair plug
US20040230303A1 (en) * 2003-05-16 2004-11-18 Gomes Katherine A. Cartilage allograft plug
US20050222687A1 (en) * 2004-04-02 2005-10-06 Gordana Vunjak-Novakovic Cartilage implant assembly and method for implantation

Also Published As

Publication number Publication date
CN101166485A (en) 2008-04-23
JP2008539814A (en) 2008-11-20
US20060247790A1 (en) 2006-11-02
WO2006119126A2 (en) 2006-11-09
AU2006242360A1 (en) 2006-11-09
CA2605719A1 (en) 2006-11-09
EP1885292A2 (en) 2008-02-13
CN101166485B (en) 2010-12-08

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