WO2006122966A3 - Use of calcium phosphate as a food supplement for lowering cholesterol, preventing coronary heart diseases and cancer and for binding bile acids - Google Patents

Use of calcium phosphate as a food supplement for lowering cholesterol, preventing coronary heart diseases and cancer and for binding bile acids Download PDF

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Publication number
WO2006122966A3
WO2006122966A3 PCT/EP2006/062418 EP2006062418W WO2006122966A3 WO 2006122966 A3 WO2006122966 A3 WO 2006122966A3 EP 2006062418 W EP2006062418 W EP 2006062418W WO 2006122966 A3 WO2006122966 A3 WO 2006122966A3
Authority
WO
WIPO (PCT)
Prior art keywords
food supplement
calcium phosphate
cancer
coronary heart
bile acids
Prior art date
Application number
PCT/EP2006/062418
Other languages
German (de)
French (fr)
Other versions
WO2006122966A2 (en
Inventor
Gerhard Jahreis
Bianka Ditscheid
Original Assignee
Chem Fab Budenheim Kg
Bk Giulini Gmbh
Gerhard Jahreis
Bianka Ditscheid
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chem Fab Budenheim Kg, Bk Giulini Gmbh, Gerhard Jahreis, Bianka Ditscheid filed Critical Chem Fab Budenheim Kg
Publication of WO2006122966A2 publication Critical patent/WO2006122966A2/en
Publication of WO2006122966A3 publication Critical patent/WO2006122966A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/42—Phosphorus; Compounds thereof
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/16—Inorganic salts, minerals or trace elements
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs

Abstract

The invention relates to a use of calcium phosphate or a combination of calcium phosphates for producing a food supplement. The aim of the invention is to create an alternative food supplement that can be produced at a low cost and does away with the drawbacks known in prior art. Said aim is achieved by a food supplement for lowering cholesterol and/or for preventing coronary heart diseases and/or cancer, especially colon cancer, and/or binding bile acids and the secretion thereof. The inventive food supplement is characterized in that the same contains calcium phosphate, in a particularly advantageous manner in the form of pentacalcium hydroxyphosphate Ca5(PO4)3OH.
PCT/EP2006/062418 2005-05-19 2006-05-18 Use of calcium phosphate as a food supplement for lowering cholesterol, preventing coronary heart diseases and cancer and for binding bile acids WO2006122966A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102005022953.0 2005-05-19
DE102005022953A DE102005022953A1 (en) 2005-05-19 2005-05-19 Dietary supplements

Publications (2)

Publication Number Publication Date
WO2006122966A2 WO2006122966A2 (en) 2006-11-23
WO2006122966A3 true WO2006122966A3 (en) 2007-08-23

Family

ID=36649438

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2006/062418 WO2006122966A2 (en) 2005-05-19 2006-05-18 Use of calcium phosphate as a food supplement for lowering cholesterol, preventing coronary heart diseases and cancer and for binding bile acids

Country Status (2)

Country Link
DE (1) DE102005022953A1 (en)
WO (1) WO2006122966A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2022045903A1 (en) * 2020-08-25 2022-03-03 Cytorex International, Inc. Method for producing mixtures to achieve ionic compositions for therapeutic use, which can be administered to humans or animals orally, parenterally, intraperitoneally, topically, otically, nasally or by means of washes, which result in improvement in diseases

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WO1992004974A1 (en) * 1990-09-17 1992-04-02 Kabushiki Kaisya Advance A lipid absorbent
JPH04158744A (en) * 1990-10-22 1992-06-01 Fuji Oil Co Ltd Production of chocolates
US6251439B1 (en) * 1998-12-16 2001-06-26 Trustee Of The Dartmouth College Composition and method for reducing the risk of carcinogenesis
WO2002066065A1 (en) * 2001-02-16 2002-08-29 Trustees Of Dartmouth College Calcium supplementation to reduce prostate cancer risk
CN1374132A (en) * 2002-03-22 2002-10-16 上海交通大学 Prepn of core-shell type nano compound hydroxyapatiti-liposome particle
WO2003090547A1 (en) * 2002-04-23 2003-11-06 Degussa Bioactives Gmbh A composition comprising waxy acids for effecting serum cholesterol levels

Family Cites Families (4)

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Publication number Priority date Publication date Assignee Title
JPS63107937A (en) * 1986-10-25 1988-05-12 Sangi:Kk Calcium agent containing synthetic hydroxyapatite
WO1999065337A1 (en) * 1998-06-19 1999-12-23 Beth Israel Deaconess Medical Center Dietary supplement for post-menopausal women
US6376481B2 (en) * 1998-09-02 2002-04-23 Mcneil-Ppc, Inc. Sterol esters in tableted solid dosage forms
US6790462B2 (en) * 2001-08-09 2004-09-14 Rhodia Inc. Calcium dietary supplement

Patent Citations (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2074603A1 (en) * 1970-01-09 1971-10-08 Monsanto Co Carboxylic acid polymers with anti-hyper - cholesteraemic activity
JPS63198630A (en) * 1987-02-13 1988-08-17 Kao Corp Lipid metabolism improver
JPH01236940A (en) * 1988-03-15 1989-09-21 Advance Co Ltd Lipid adsorbent
JPH01315337A (en) * 1988-06-14 1989-12-20 Advance Co Ltd Lipid adsorbent
WO1992004974A1 (en) * 1990-09-17 1992-04-02 Kabushiki Kaisya Advance A lipid absorbent
CA2038929A1 (en) * 1990-09-18 1992-03-19 Shigeru Tsukagoshi Lipid absorbent
WO1992004975A1 (en) * 1990-09-18 1992-04-02 Kabushiki Kaisya Advance Lipid adsorbent
JPH04158744A (en) * 1990-10-22 1992-06-01 Fuji Oil Co Ltd Production of chocolates
US6251439B1 (en) * 1998-12-16 2001-06-26 Trustee Of The Dartmouth College Composition and method for reducing the risk of carcinogenesis
WO2002066065A1 (en) * 2001-02-16 2002-08-29 Trustees Of Dartmouth College Calcium supplementation to reduce prostate cancer risk
CN1374132A (en) * 2002-03-22 2002-10-16 上海交通大学 Prepn of core-shell type nano compound hydroxyapatiti-liposome particle
WO2003090547A1 (en) * 2002-04-23 2003-11-06 Degussa Bioactives Gmbh A composition comprising waxy acids for effecting serum cholesterol levels

Non-Patent Citations (23)

* Cited by examiner, † Cited by third party
Title
DATABASE EMBASE [online] ELSEVIER SCIENCE PUBLISHERS, AMSTERDAM, NL; 1990, VAN DER MEER R ET AL: "Effects of supplemental dietary calcium on the intestinal association of calcium, phosphate, and bile acids", XP002415791, Database accession no. EMB-1991013645 *
DATABASE FSTA [online] INTERNATIONAL FOOD INFORMATION SERVICE (IFIS), FRANkFURT-MAIN, DE; 2004, WADE M A: "Calcium: the chosen form.", XP002415786, retrieved from FSTA Database accession no. 2004-00-g0715 *
DATABASE MEDLINE [online] US NATIONAL LIBRARY OF MEDICINE (NLM), BETHESDA, MD, US; 1 July 1985 (1985-07-01), VAN DER MEER R ET AL: "Differential binding of glycine- and taurine-conjugated bile acids to insoluble calcium phosphate.", XP002415789, Database accession no. NLM4038261 *
DATABASE MEDLINE [online] US NATIONAL LIBRARY OF MEDICINE (NLM), BETHESDA, MD, US; January 1991 (1991-01-01), VAN DER MEER R ET AL: "Differential effects of calcium ions and calcium phosphate on cytotoxicity of bile acids.", XP002415790, Database accession no. NLM1987802 *
DATABASE MEDLINE [online] US NATIONAL LIBRARY OF MEDICINE (NLM), BETHESDA, MD, US; October 1991 (1991-10-01), VAN DER MEER R ET AL: "Calcium phosphate, bile acids and colorectal cancer.", XP002415787, Database accession no. NLM1842734 *
DATABASE MEDLINE [online] US NATIONAL LIBRARY OF MEDICINE (NLM), BETHESDA, MD, US; September 1998 (1998-09-01), VAN DEN BERG A A ET AL: "Mucins and calcium phosphate precipitates additively stimulate cholesterol crystallization.", XP002415788, Database accession no. NLM9741686 *
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GASTROENTEROLOGY 1990 UNITED STATES, vol. 99, no. 6, 1990, pages 1653 - 1659, ISSN: 0016-5085 *
GOVERS M J A P ET AL: "Characterization of the adsorption of conjugated and unconjugated bile acids to insoluble, amorphous calcium phosphate", JOURNAL OF LIPID RESEARCH, BETHESDA, MD, US, vol. 35, no. 5, May 1994 (1994-05-01), pages 741 - 748, XP002256201, ISSN: 0022-2275 *
JOURNAL OF LIPID RESEARCH SEP 1998, vol. 39, no. 9, September 1998 (1998-09-01), pages 1744 - 1751, ISSN: 0022-2275 *
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PATENT ABSTRACTS OF JAPAN vol. 016, no. 449 (C - 0986) 18 September 1992 (1992-09-18) *
SESINK A L A ET AL: "RED MEAT AND COLON CANCER: DIETARY HAEM-INDUCED COLONIC CYTOTOXICITY AND EPITHELIAL HYPERPROLIFERATION ARE INHIBITED BY CALCIUM", CARCINOGENESIS, IRL PRESS, LONDON, GB, vol. 22, no. 10, October 2001 (2001-10-01), pages 1653 - 1659, XP009009599, ISSN: 0143-3334 *
THE AMERICAN JOURNAL OF PHYSIOLOGY JAN 1991, vol. 260, no. 1 Pt 1, January 1991 (1991-01-01), pages G142 - G147, ISSN: 0002-9513 *
THE BIOCHEMICAL JOURNAL 1 JUL 1985, vol. 229, no. 1, 1 July 1985 (1985-07-01), pages 265 - 268, ISSN: 0264-6021 *
VAN DER MEER R ET AL: "Differential binding of glycine- and taurine-conjugated bile acids to insoluble calcium phosphate", BIOCHEMICAL JOURNAL 1985 UNITED KINGDOM, vol. 229, no. 1, 1985, pages 265 - 268, XP002415785 *
WADE M A, PREPARED FOODS, vol. 173, no. 5, 2004, pages 61-62, 64, 66-67 *

Also Published As

Publication number Publication date
DE102005022953A1 (en) 2006-11-23
WO2006122966A2 (en) 2006-11-23

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