WO2006123329B1 - Disposable dispenser for patient infusion - Google Patents

Disposable dispenser for patient infusion

Info

Publication number
WO2006123329B1
WO2006123329B1 PCT/IL2006/000569 IL2006000569W WO2006123329B1 WO 2006123329 B1 WO2006123329 B1 WO 2006123329B1 IL 2006000569 W IL2006000569 W IL 2006000569W WO 2006123329 B1 WO2006123329 B1 WO 2006123329B1
Authority
WO
WIPO (PCT)
Prior art keywords
pump
housing
delivery tool
fluid delivery
dispenser
Prior art date
Application number
PCT/IL2006/000569
Other languages
French (fr)
Other versions
WO2006123329A3 (en
WO2006123329A2 (en
Inventor
Gavriel J Iddan
Ofer Yodfat
Original Assignee
Medingo Ltd
Gavriel J Iddan
Ofer Yodfat
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medingo Ltd, Gavriel J Iddan, Ofer Yodfat filed Critical Medingo Ltd
Priority to US11/920,469 priority Critical patent/US8105280B2/en
Priority to DK06728351.5T priority patent/DK1881820T3/en
Priority to EP06728351.5A priority patent/EP1881820B1/en
Publication of WO2006123329A2 publication Critical patent/WO2006123329A2/en
Publication of WO2006123329A3 publication Critical patent/WO2006123329A3/en
Publication of WO2006123329B1 publication Critical patent/WO2006123329B1/en
Priority to US13/361,621 priority patent/US8663165B2/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/14244—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/168—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
    • A61M5/16804—Flow controllers
    • A61M5/16809—Flow controllers by repeated filling and emptying of an intermediate volume
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/168—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
    • A61M5/172—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body electrical or electronic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/02—General characteristics of the apparatus characterised by a particular materials
    • A61M2205/0244—Micromachined materials, e.g. made from silicon wafers, microelectromechanical systems [MEMS] or comprising nanotechnology
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/35—Communication
    • A61M2205/3546—Range
    • A61M2205/3569—Range sublocal, e.g. between console and disposable
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/35—Communication
    • A61M2205/3576—Communication with non implanted data transmission devices, e.g. using external transmitter or receiver
    • A61M2205/3592—Communication with non implanted data transmission devices, e.g. using external transmitter or receiver using telemetric means, e.g. radio or optical transmission
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/36—General characteristics of the apparatus related to heating or cooling
    • A61M2205/3606—General characteristics of the apparatus related to heating or cooling cooled
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/002—Packages specially adapted therefor, e.g. for syringes or needles, kits for diabetics
    • A61M5/003—Kits for diabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/14212—Pumping with an aspiration and an expulsion action
    • A61M5/14224—Diaphragm type
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/14212—Pumping with an aspiration and an expulsion action
    • A61M5/14232—Roller pumps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/14212—Pumping with an aspiration and an expulsion action
    • A61M5/14236—Screw, impeller or centrifugal type pumps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/14244—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
    • A61M5/14248—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body of the skin patch type
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/42—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for desensitising skin, for protruding skin to facilitate piercing, or for locating point where body is to be pierced
    • A61M5/422—Desensitising skin

Abstract

Embodiments of the invention are directed to methods and systems associated with a disposable dispenser (100, 200) of therapeutic fluid. Preferred embodiments having a small size of less than about 75mm in length, less than 50 mm in width and less than about 10 mm in thickness and may be releasably attached to the body (B). In one embodiments, the dispenser draws fluid from a flexible volume-conformable reservoir (4) and operates a dosing and metering pump (6, 61, 62, 63) incorporating a motor to deliver fluid through a fluid delivery tool (8, 81, 82). Disposed on the housing bottom (2B) is a peel-of-tape (22) that when removed, electrically connects a power supply (18) to power the operative components (3) of the dispenser into operation, exposes an adhesive (28) and a window (21) opened in the housing (2), and allows the fluid delivery tool (8) to extend for insertion into the skin (S).

Claims

29
AMENDED CLAIMS [Received by the International Bureau on 28 May 2007 (28.05.2007)]
1. A disposable dispenser (100, 200) having a thin flat planar construction, for infusing a therapeutic fluid through the skin (S) into the body (B) of a user (U), the dispenser (100) comprising: a housing (2) with a top face (2U), a bottom face (2B), a front side (2F), an exterior (2E), and an interior (2T) accommodating therein operative components (3); a power supply source (18) provided within the housing interior (21) for powering the dispenser (100); an electronic circuit (16, 161, 162) within the housing interior (21), the circuit including a programmable controller (12) for control, management and operation of the dispenser (100, 200), and a transceiver (14T) operating a wireless bi-directional communication channel (14) coupled to the programmable controller (12), the transceiver receiving and transmitting data, commands and instructions, and a fluid delivery tool (8,) arranged at the housing front side (2F) and within the housing interior (21), the fluid delivery tool being coupled to a pump (6, 61 , 62) and being inserted via an opening which forms a window (21) that is established in the housing bottom face (2B), the fluid delivery tool being inserted through the skin (S) into the body (B) of the user (U) to deliver controlled doses of therapeutic fluid, characterized by: the housing (2) having a planar surface and containing the fluid delivery tool (8) which extends for use and is capable of folding for stowage into a box (58) for sale disposal, a flexible volume-conformable reservoir (4) filled with therapeutic fluid within the housing interior (21), a flat planar dosing and metering pump (6, 61, 62) arranged within the housing interior incorporating a motor, the pump being coupled in fluid communication with and downstream of the reservoir (4), to deliver sequential unit doses of therapeutic fluid at a controlled flow rate via the downstream disposed fluid delivery tool (8), a length of removable tape (22) arranged on the housing bottom (2B) that upon removal, allows electrical connection with the power supply (18) to power the operative components (3) of the dispenser (100, 200) into operation, the removal of the tape exposes an adhesive (28) and the window (21) whereout the fluid delivery tool (8) deploys and extends for insertion through the skin (S). 30
the method being characterized by the steps of : configuring the housing (2) to contain the fluid delivery tool (8) which extends for use, and which folds for safe disposal alongside the housing bottom face (2B), for safe stowage into a box (58), disposing within the housing interior (21) a thin flat planar dosing and metering pump (6) incorporating a motor, the pump being coupled in fluid communication with and downstream of the reservoir (4), to deliver sequential unit doses of therapeutic fluid at a controlled flow rate via the downstream disposed fluid delivery tool (8), and disposing on the housing bottom (2B) a peel-of-tape (22) that upon removal allows electrical connection to the power supply (18) to power the operative components (3) of the dispenser (100) into operation, the removal of the peel-off tape (22) exposing an adhesive (28) and the window (21), and allows the fluid delivery tool (8) to deploy and extend for insertion through the skin (S).
23. The method according to Claim 21, wherein: the dosing and metering pump (6) is implemented as a single-gear peristaltic pump (63) having a counter plate (51) and is embodied in flat planar configuration.
24. The method according to Claim 22, wherein: the dosing and metering pump (6) is implemented as an electromagnetic membrane pump (61) and is embodied in flat planar configuration
25. The method according to Claim 22, wherein: the dosing and metering pump (6) is implemented as a gear-on-gear pump (62) and is embodied in flat planar configuration.
26. The method according to Claim 22, wherein: the. dosing and metering pump (6) is implemented as a pump selected out of the group consisting of an electromagnetic membrane pump (61), a gear-on-gear pump (62) and a sing5e-gear peristaltic pump (63), and is controllable to deliver predetermined single quantum unit doses and sequential successive single quantum unit doses.
PCT/IL2006/000569 2005-05-17 2006-05-14 Disposable dispenser for patient infusion WO2006123329A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
US11/920,469 US8105280B2 (en) 2005-05-17 2006-05-14 Disposable dispenser for patient infusion
DK06728351.5T DK1881820T3 (en) 2005-05-17 2006-05-14 Disposable dispenser for patient infusion
EP06728351.5A EP1881820B1 (en) 2005-05-17 2006-05-14 Disposable dispenser for patient infusion
US13/361,621 US8663165B2 (en) 2005-05-17 2012-01-30 Disposable dispenser for patient infusion

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IL16864205 2005-05-17
IL168642 2005-05-17

Related Child Applications (2)

Application Number Title Priority Date Filing Date
US11/920,469 A-371-Of-International US8105280B2 (en) 2005-05-17 2006-05-14 Disposable dispenser for patient infusion
US13/361,621 Continuation US8663165B2 (en) 2005-05-17 2012-01-30 Disposable dispenser for patient infusion

Publications (3)

Publication Number Publication Date
WO2006123329A2 WO2006123329A2 (en) 2006-11-23
WO2006123329A3 WO2006123329A3 (en) 2007-06-07
WO2006123329B1 true WO2006123329B1 (en) 2007-08-09

Family

ID=37431659

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IL2006/000569 WO2006123329A2 (en) 2005-05-17 2006-05-14 Disposable dispenser for patient infusion

Country Status (4)

Country Link
US (2) US8105280B2 (en)
EP (1) EP1881820B1 (en)
DK (1) DK1881820T3 (en)
WO (1) WO2006123329A2 (en)

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WO2006123329A3 (en) 2007-06-07
EP1881820A4 (en) 2014-11-12
US20080234630A1 (en) 2008-09-25
WO2006123329A2 (en) 2006-11-23
EP1881820B1 (en) 2020-06-17
US20120197197A1 (en) 2012-08-02
EP1881820A2 (en) 2008-01-30
US8663165B2 (en) 2014-03-04
US8105280B2 (en) 2012-01-31
DK1881820T3 (en) 2020-08-24

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