WO2007011955A3 - Drug-containing implants and methods of use thereof - Google Patents
Drug-containing implants and methods of use thereof Download PDFInfo
- Publication number
- WO2007011955A3 WO2007011955A3 PCT/US2006/027894 US2006027894W WO2007011955A3 WO 2007011955 A3 WO2007011955 A3 WO 2007011955A3 US 2006027894 W US2006027894 W US 2006027894W WO 2007011955 A3 WO2007011955 A3 WO 2007011955A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- drug
- present
- methods
- implants
- containing implants
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/549—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame having two or more nitrogen atoms in the same ring, e.g. hydrochlorothiazide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/60—Salicylic acid; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/18—Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/54—Biologically active materials, e.g. therapeutic substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/18—Feminine contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
- A61L2300/22—Lipids, fatty acids, e.g. prostaglandins, oils, fats, waxes
- A61L2300/222—Steroids, e.g. corticosteroids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/402—Anaestetics, analgesics, e.g. lidocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/41—Anti-inflammatory agents, e.g. NSAIDs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
- A61L2300/602—Type of release, e.g. controlled, sustained, slow
- A61L2300/604—Biodegradation
Abstract
Priority Applications (15)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU2006269927A AU2006269927B2 (en) | 2004-01-12 | 2006-07-18 | Drug-containing implants and methods of use thereof |
KR1020087003822A KR101283946B1 (en) | 2005-07-18 | 2006-07-18 | Drug-containing implants and methods of use thereof |
JP2008522903A JP5405825B2 (en) | 2005-07-18 | 2006-07-18 | Drug-containing implant and method of using the same |
EP06787745A EP1909689A4 (en) | 2005-07-18 | 2006-07-18 | Drug-containing implants and methods of use thereof |
MX2014012310A MX362908B (en) | 2005-07-18 | 2006-07-18 | Drug-containing implants and methods of use thereof. |
MX2008000573A MX2008000573A (en) | 2005-07-18 | 2006-07-18 | Drug-containing implants and methods of use thereof. |
US11/988,137 US8741327B2 (en) | 2004-01-12 | 2006-07-18 | Method of maintaining therapeutic risperidone levels in a PLA:PLGA implant |
CA2614601A CA2614601C (en) | 2005-07-18 | 2006-07-18 | Drug-containing implants and methods of use thereof |
US13/490,787 US8802127B2 (en) | 2004-01-12 | 2012-06-07 | Risperidone-containing PLA:PGA implants and methods of use thereof |
US14/286,168 US9439905B2 (en) | 2004-01-12 | 2014-05-23 | Risperidone-containing implants and methods of use thereof |
US14/540,828 US9717799B2 (en) | 2004-01-12 | 2014-11-13 | Drug-containing implants and methods of use thereof |
US15/627,389 US9895447B2 (en) | 2004-01-12 | 2017-06-19 | Drug-containing PLA implants and methods of use thereof |
US15/627,349 US9925268B2 (en) | 2004-01-12 | 2017-06-19 | Drug-containing implants and methods of use thereof |
US15/863,483 US10111960B2 (en) | 2004-01-12 | 2018-01-05 | 9-OH-risperidone controlled release composition |
US16/174,083 US10736965B2 (en) | 2004-01-12 | 2018-10-29 | Risperidone biodegradable implant |
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US11/183,232 US8221778B2 (en) | 2005-01-12 | 2005-07-18 | Drug-containing implants and methods of use thereof |
US11/183,232 | 2005-07-18 | ||
US11/195,845 US8329203B2 (en) | 2004-01-12 | 2005-08-03 | Drug-containing implants and methods of use thereof |
US11/195,845 | 2005-08-03 |
Related Parent Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US11/183,232 Continuation-In-Part US8221778B2 (en) | 2004-01-12 | 2005-07-18 | Drug-containing implants and methods of use thereof |
US11/195,845 Continuation US8329203B2 (en) | 2004-01-12 | 2005-08-03 | Drug-containing implants and methods of use thereof |
US11/195,845 Continuation-In-Part US8329203B2 (en) | 2004-01-12 | 2005-08-03 | Drug-containing implants and methods of use thereof |
Related Child Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US11/988,137 A-371-Of-International US8741327B2 (en) | 2004-01-12 | 2006-07-18 | Method of maintaining therapeutic risperidone levels in a PLA:PLGA implant |
US12/988,137 Continuation-In-Part US20110037616A1 (en) | 2008-04-16 | 2009-03-12 | Method for monitoring a traffic route for a means of transport of a predetermined kind |
US13/490,787 Continuation US8802127B2 (en) | 2004-01-12 | 2012-06-07 | Risperidone-containing PLA:PGA implants and methods of use thereof |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2007011955A2 WO2007011955A2 (en) | 2007-01-25 |
WO2007011955A3 true WO2007011955A3 (en) | 2007-12-13 |
Family
ID=37669513
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2006/027894 WO2007011955A2 (en) | 2004-01-12 | 2006-07-18 | Drug-containing implants and methods of use thereof |
Country Status (8)
Country | Link |
---|---|
EP (1) | EP1909689A4 (en) |
JP (3) | JP5405825B2 (en) |
KR (1) | KR101283946B1 (en) |
CN (1) | CN103637977A (en) |
AU (1) | AU2006269927B2 (en) |
CA (1) | CA2614601C (en) |
MX (2) | MX2008000573A (en) |
WO (1) | WO2007011955A2 (en) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8221778B2 (en) | 2005-01-12 | 2012-07-17 | The Trustees Of The University Of Pennsylvania | Drug-containing implants and methods of use thereof |
MX2008000573A (en) * | 2005-07-18 | 2008-03-14 | Univ Pennsylvania | Drug-containing implants and methods of use thereof. |
US8852638B2 (en) | 2005-09-30 | 2014-10-07 | Durect Corporation | Sustained release small molecule drug formulation |
MX337286B (en) | 2007-05-25 | 2016-02-22 | Indivior Uk Ltd | Sustained delivery formulations of risperidone compounds. |
US8889173B2 (en) * | 2008-04-18 | 2014-11-18 | Warsaw Orthopedic, Inc. | Alpha adrenergic receptor agonists for treatment of pain and/or inflammation |
US9078900B2 (en) * | 2008-09-30 | 2015-07-14 | Braeburn Pharmaceuticals Bvba Sprl | Implantable device for the delivery of risperidone and methods of use thereof |
WO2010105093A2 (en) * | 2009-03-12 | 2010-09-16 | Delpor, Inc. | Implantable device for long-term delivery of drugs |
JP2011001273A (en) * | 2009-06-16 | 2011-01-06 | Eci Inc | WATER-SOLUBLE PREPARATION COMPRISING eMIP AS ACTIVE INGREDIENT |
US20110159066A1 (en) * | 2009-11-02 | 2011-06-30 | Sebree Terri B | Methods For Treating Parkinson's Disease |
EP2366378A1 (en) | 2010-03-01 | 2011-09-21 | Dexcel Pharma Technologies Ltd. | Sustained-release donepezil formulations |
WO2012070034A1 (en) * | 2010-11-26 | 2012-05-31 | University Of The Witwatersrand, Johannesburg | A drug delivery device |
TWI552751B (en) | 2011-06-20 | 2016-10-11 | H 朗德貝克公司 | Method of administration of 4-((1r,3s)-6-chloro-3-phenyl-indan-1-yl)-1,2,2-trimethyl-piperazine and the salts thereof in the treatment of schizophrenia |
MX368099B (en) | 2013-05-14 | 2019-09-19 | Eisai R&D Man Co Ltd | Biomarkers for predicting and assessing responsiveness of endometrial cancer subjects to lenvatinib compounds. |
CA2978226A1 (en) | 2015-03-04 | 2016-09-09 | Merck Sharpe & Dohme Corp. | Combination of a pd-1 antagonist and a vegfr/fgfr/ret tyrosine kinase inhibitor for treating cancer |
CN104922085B (en) * | 2015-06-01 | 2016-10-26 | 湖南赛沃药业有限公司 | A kind of risperidone implant and preparation method thereof |
EP3377041B1 (en) | 2015-11-16 | 2023-10-25 | MedinCell S.A. | A method for morselizing and/or targeting pharmaceutically active principles to synovial tissue |
EP3600258A1 (en) | 2017-03-20 | 2020-02-05 | Teva Pharmaceuticals International GmbH | Sustained release olanzapine formulaitons |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4351337A (en) * | 1973-05-17 | 1982-09-28 | Arthur D. Little, Inc. | Biodegradable, implantable drug delivery device, and process for preparing and using the same |
US20020179096A1 (en) * | 2000-10-20 | 2002-12-05 | Siegel Steven J. | Polymer-based surgically implantable haloperidol delivery systems and methods for their production and use |
Family Cites Families (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS58216117A (en) * | 1982-06-09 | 1983-12-15 | Mitsui Toatsu Chem Inc | Preparation of rod-shaped slow-releasing formed drug |
JPS63203610A (en) * | 1987-02-12 | 1988-08-23 | ヘキスト・アクチエンゲゼルシヤフト | Long life medicine comprising plural components for implant |
JPS6471823A (en) * | 1987-09-12 | 1989-03-16 | Rohto Pharma | Sustained remedy for vaginal candidiasis |
JP2702729B2 (en) * | 1988-02-24 | 1998-01-26 | エーザイ株式会社 | Sustained release implant |
JPH04217914A (en) * | 1990-05-10 | 1992-08-07 | Nkk Corp | Production of sustained release pharmaceutical |
US5629008A (en) * | 1992-06-02 | 1997-05-13 | C.R. Bard, Inc. | Method and device for long-term delivery of drugs |
KR100333115B1 (en) * | 1992-11-17 | 2002-12-02 | 미츠비시 파마 코포레이션 | Sustained-release microsphere containing antipsychotic and process for producing the same |
ES2236700T3 (en) * | 1993-11-19 | 2005-07-16 | Janssen Pharmaceutica N.V. | 1,2-MICROENCAPSULATED BENZAZOLS. |
US5792477A (en) * | 1996-05-07 | 1998-08-11 | Alkermes Controlled Therapeutics, Inc. Ii | Preparation of extended shelf-life biodegradable, biocompatible microparticles containing a biologically active agent |
JP2002511075A (en) * | 1997-06-04 | 2002-04-09 | デビオ ルシェルシュ ファルマスティク ソシエテ アノニム | Implant for controlled release of pharmaceutically active ingredient and method for producing the same |
US6264987B1 (en) * | 2000-05-19 | 2001-07-24 | Alkermes Controlled Therapeutics Inc. Ii | Method for preparing microparticles having a selected polymer molecular weight |
WO2003020200A2 (en) * | 2000-11-16 | 2003-03-13 | New River Pharmaceuticals Inc. | A novel pharmaceutical compound and methods of making and using same |
US6824822B2 (en) * | 2001-08-31 | 2004-11-30 | Alkermes Controlled Therapeutics Inc. Ii | Residual solvent extraction method and microparticles produced thereby |
JP2006516947A (en) * | 2000-11-16 | 2006-07-13 | ニュー リバー ファーマシューティカルズ インコーポレイテッド | Novel pharmaceutical compound and method for producing and using the same |
GB0304726D0 (en) * | 2003-03-01 | 2003-04-02 | Ardana Bioscience Ltd | New Process |
ITMI20031302A1 (en) * | 2003-06-26 | 2004-12-27 | Mediolanum Pharmaceuticals Ltd | USE OF ETHANOL AS A PLASTICIZER TO PREPARE SUBCUTANEOUS IMPLANTS CONTAINING THERMALABLE ACTIVE PRINCIPLES DISPERSED IN A PLGA MATRIX. |
JP5306599B2 (en) * | 2004-01-12 | 2013-10-02 | ザ トラスティーズ オブ ザ ユニバーシティ オブ ペンシルバニア | Long-term delivery formulation |
AU2005325213B2 (en) * | 2004-08-04 | 2010-10-07 | Evonik Corporation | Methods for manufacturing delivery devices and devices thereof |
MX2008000573A (en) * | 2005-07-18 | 2008-03-14 | Univ Pennsylvania | Drug-containing implants and methods of use thereof. |
US8852638B2 (en) * | 2005-09-30 | 2014-10-07 | Durect Corporation | Sustained release small molecule drug formulation |
-
2006
- 2006-07-18 MX MX2008000573A patent/MX2008000573A/en not_active Application Discontinuation
- 2006-07-18 JP JP2008522903A patent/JP5405825B2/en active Active
- 2006-07-18 AU AU2006269927A patent/AU2006269927B2/en active Active
- 2006-07-18 CN CN201310587181.8A patent/CN103637977A/en active Pending
- 2006-07-18 EP EP06787745A patent/EP1909689A4/en not_active Ceased
- 2006-07-18 KR KR1020087003822A patent/KR101283946B1/en active IP Right Grant
- 2006-07-18 MX MX2014012310A patent/MX362908B/en unknown
- 2006-07-18 WO PCT/US2006/027894 patent/WO2007011955A2/en active Application Filing
- 2006-07-18 CA CA2614601A patent/CA2614601C/en active Active
-
2013
- 2013-10-07 JP JP2013210074A patent/JP2014001246A/en active Pending
-
2015
- 2015-01-23 JP JP2015010783A patent/JP6153952B2/en active Active
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4351337A (en) * | 1973-05-17 | 1982-09-28 | Arthur D. Little, Inc. | Biodegradable, implantable drug delivery device, and process for preparing and using the same |
US20020179096A1 (en) * | 2000-10-20 | 2002-12-05 | Siegel Steven J. | Polymer-based surgically implantable haloperidol delivery systems and methods for their production and use |
Non-Patent Citations (1)
Title |
---|
See also references of EP1909689A4 * |
Also Published As
Publication number | Publication date |
---|---|
CA2614601A1 (en) | 2007-01-25 |
CA2614601C (en) | 2015-04-07 |
MX362908B (en) | 2019-02-21 |
CN103637977A (en) | 2014-03-19 |
JP2014001246A (en) | 2014-01-09 |
EP1909689A4 (en) | 2011-11-16 |
JP2009501798A (en) | 2009-01-22 |
AU2006269927B2 (en) | 2013-05-16 |
JP2015078233A (en) | 2015-04-23 |
KR101283946B1 (en) | 2013-07-15 |
MX2008000573A (en) | 2008-03-14 |
AU2006269927A1 (en) | 2007-01-25 |
EP1909689A2 (en) | 2008-04-16 |
JP6153952B2 (en) | 2017-06-28 |
JP5405825B2 (en) | 2014-02-05 |
KR20080033991A (en) | 2008-04-17 |
WO2007011955A2 (en) | 2007-01-25 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
WO2007011955A3 (en) | Drug-containing implants and methods of use thereof | |
WO2007146426A3 (en) | Nanoshells for drug delivery | |
WO2004010975A3 (en) | Controlled drug delivery | |
WO2006049907A3 (en) | Implantable devices comprising biologically absorbable star polymers | |
EP2322219A3 (en) | Use of IL-23 and IL-17 antagonists to treat autoimmune ocular inflammatory disease | |
WO2008021113A3 (en) | Transdermal methods and systems for treating alzheimer's disease | |
WO2007023408A3 (en) | 4d image-based planning methods and apparatus for targeted therapy | |
WO2007015739A3 (en) | Pea-tempo/pea-bz coatings for controlled delivery of drugs from implantable medical devices | |
EP2407203A3 (en) | Solid therapeutic agent for use in an implantable drug delivery device | |
WO2008036144A3 (en) | Nanoshells on polymers | |
EP1781354A4 (en) | An occludable intravascular catheter for drug delivery and method of using the same | |
WO2007126768A3 (en) | Medical devices comprising a porous metal oxide or metal material and a polymer coating for delivering therapeutic agents | |
EP1809369A4 (en) | Medical devices for the detection, prevention and/or treatment of neurological disorders, and methods related thereto | |
AU2003245282A1 (en) | Stent coatings with sustained drug release rate | |
WO2006060507A3 (en) | Compositions comprising immunomodulatory compounds and the use thereof for the treatment of immunodeficiency disorders | |
WO2010068281A3 (en) | Contact lens drug delivery device | |
WO2007002390A3 (en) | Compositions and methods for modulation of smn2 splicing | |
MX2007002189A (en) | Diketopiperazine salts, diketomorpholine salts or diketodioxane salts for drug delivery. | |
ATE554725T1 (en) | SURGICAL ARTICLES FOR THE TREATMENT OF PELVIC DISEASES | |
ATE530142T1 (en) | SURGICAL ARTICLES FOR THE TREATMENT OF PELVIC DISEASES | |
TWI372056B (en) | Novel medicament combinations for the treatment of respiratory diseases | |
ATE413162T1 (en) | PHARMACEUTICAL COMPOSITIONS FOR THE SAFE ADMINISTRATION OF DRUGS USED IN THE TREATMENT OF DRUG DEPENDENCE | |
CY1120433T1 (en) | MELATONIN AGRICULTURAL TREATMENT | |
WO2008027912A3 (en) | Prediction of an agent's or agents' activity across different cells and tissue types | |
WO2006085115A3 (en) | Therapeutic uses of tomato extracts |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
WWE | Wipo information: entry into national phase |
Ref document number: 200680034307.7 Country of ref document: CN |
|
121 | Ep: the epo has been informed by wipo that ep was designated in this application | ||
WWE | Wipo information: entry into national phase |
Ref document number: 2006269927 Country of ref document: AU |
|
ENP | Entry into the national phase |
Ref document number: 2614601 Country of ref document: CA |
|
WWE | Wipo information: entry into national phase |
Ref document number: MX/a/2008/000573 Country of ref document: MX |
|
WWE | Wipo information: entry into national phase |
Ref document number: 2008522903 Country of ref document: JP |
|
WWE | Wipo information: entry into national phase |
Ref document number: 2006787745 Country of ref document: EP |
|
NENP | Non-entry into the national phase |
Ref country code: DE |
|
ENP | Entry into the national phase |
Ref document number: 2006269927 Country of ref document: AU Date of ref document: 20060718 Kind code of ref document: A |
|
WWE | Wipo information: entry into national phase |
Ref document number: 1020087003822 Country of ref document: KR |
|
WWE | Wipo information: entry into national phase |
Ref document number: 11988137 Country of ref document: US |