WO2007012861A1 - Dispositif indicateur de compte de type jauge supporte sur cartouche pour inhalateur-doseur - Google Patents

Dispositif indicateur de compte de type jauge supporte sur cartouche pour inhalateur-doseur Download PDF

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Publication number
WO2007012861A1
WO2007012861A1 PCT/GB2006/002808 GB2006002808W WO2007012861A1 WO 2007012861 A1 WO2007012861 A1 WO 2007012861A1 GB 2006002808 W GB2006002808 W GB 2006002808W WO 2007012861 A1 WO2007012861 A1 WO 2007012861A1
Authority
WO
WIPO (PCT)
Prior art keywords
canister
count
inhaler
counter
counter body
Prior art date
Application number
PCT/GB2006/002808
Other languages
English (en)
Inventor
Robert Owen Kivlin
Francis Dominic Lloyd-Lucas
Original Assignee
Cambridge Consultants Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cambridge Consultants Limited filed Critical Cambridge Consultants Limited
Publication of WO2007012861A1 publication Critical patent/WO2007012861A1/fr

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0065—Inhalators with dosage or measuring devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0065—Inhalators with dosage or measuring devices
    • A61M15/0068—Indicating or counting the number of dispensed doses or of remaining doses
    • A61M15/007—Mechanical counters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0065—Inhalators with dosage or measuring devices
    • A61M15/0068—Indicating or counting the number of dispensed doses or of remaining doses
    • A61M15/007—Mechanical counters
    • A61M15/0071—Mechanical counters having a display or indicator
    • A61M15/0075—Mechanical counters having a display or indicator on a disc
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/009—Inhalators using medicine packages with incorporated spraying means, e.g. aerosol cans
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06M—COUNTING MECHANISMS; COUNTING OF OBJECTS NOT OTHERWISE PROVIDED FOR
    • G06M1/00—Design features of general application
    • G06M1/04—Design features of general application for driving the stage of lowest order
    • G06M1/06—Design features of general application for driving the stage of lowest order producing continuous revolution of the stage, e.g. with gear train
    • G06M1/064—Design features of general application for driving the stage of lowest order producing continuous revolution of the stage, e.g. with gear train for dial, pointer, or similar type indicating means

Definitions

  • This application relates to a dose counter assembly, and in particular, to a dose counter assembly having an improved dosage indicator for indicating the number of metered dosages that have been dispensed from, or remain in, a canister.
  • Patients having certain conditions can be treated with medicaments dispersed in an aerosol form and administered to that patient by inhalation.
  • the aerosol and medicaments are contained in a canister or container, and dispensed in metered or measured dosages from an inhalation device.
  • the inhalation device it is important for the inhalation device to provide an accurate indication of either the number of doses remaining in the canister, or the number of doses already dispensed therefrom.
  • a conventional aerosol canister typically includes a body and a valve stem extending from one end of the body to emit a metered dose of aerosol and medicament.
  • the canister is usually supplied with a predetermined number of metered doses, generally between 100 and 200 doses of medicament although products outside of this range exist.
  • the aerosol canister is removable from the inhaler housing to permit effective cleaning of the structure defining the airflow path.
  • the housing is designed to accept a succession of user-introduced aerosol medicament canisters, as well as to provide for canister removal for cleaning.
  • U.S. Pat. No. 6,142,339 describes an inhalation device having a dose counter including a worm gear screw and a ratchet drive in a housing and an indicator having a circular gear thereon for engaging the worm gear screw.
  • a canister is received within the housing and is reciprocally movable along a longitudinal axis of the housing. The reciprocal movement of the canister drives the ratchet and the worm gear to rotate, which in turn drives the indicator to advance and to count a dosage.
  • the dose counter disclosed in the U.S. Pat. No. 6,142,339 is not linked to a specific canister or removable from the housing . If a user swaps a new canister with the canister associated with the housing, the dosage on the dose indicator which is attached to the housing does not show the correct remaining dosage of the new canister.
  • U.S. Pat. No. 6,435,372 describes a dose counter also attached to the housing, but not to the canister. Again, the device presents a danger that the dose indicator may show incorrect remaining dosage of the canister if the canister has been swapped with another canister by the user
  • WO 2006/062450 describes a dose counter attached to the top of a canister, but does not mention whether the canister can be removed for cleaning, an essential requirement for long term use. Assuming arguendo, that the canister could be removed, the dose counter would be exposed to unintentional misuse or could be tampered with so that the dose indicator may show incorrect remaining dosage of the canister.
  • a dose counter assembly for use with a medicament dispensing device, preferably a metered dose inhaler.
  • the dose counter assembly is canister-supported and has a gauge-type count readout.
  • the inhaler includes a housing disposed about a longitudinal axis with a mouthpiece section at one end and an end cap at the other end, a canister extending along a central axis, and a dose counter assembly mounted on the canister.
  • the gauge can show a complete range of fullness of the canister and the user can view an indication of the usage of, or remaining doses in the canister.
  • the canister can be a known type of aerosol dispensing canister in the art, which generally has a cylindrical shape.
  • a patient either presses downward so as to put downward pressure on the canister, or inhales at the mouthpiece causing the canister to move downward to an activated position, allowing the release of a measured dose of medicament through a dispensing nozzle of the canister and into the mouthpiece at the same time as the patient breathes in.
  • the patient inhales air with a metered dose of medicament.
  • the canister then returns to a rest position.
  • the canister is received within the housing, where the central axis of the canister is substantially coaxial with the longitudinal axis of the housing.
  • the canister is reciprocally moveable along the longitudinal axis of the housing.
  • the dose counter assembly is attached to the canister and received within the housing of the inhaler.
  • the canister includes a sleeve, which has an annular shape and is mounted on an outer surface of the canister, and the dose counter assembly is attached to an outer surface of the sleeve and received within the housing of the inhaler.
  • the dose counter assembly includes a counter body adapted to be attached to an outer surface of the sleeve, a ratchet wheel rotatably mounted on the counter body, a worm gear fixedly mounted on the ratchet wheel and being rotatable with the ratchet wheel, an indicator rotatably mounted on the counter body, and activating means mounted on the outer surface of the sleeve.
  • the ratchet wheel has ratchet teeth on an outer circumference of the ratchet wheel and is rotatable about a central rotation axis.
  • the worm gear has threads thereon and is rotatable with the ratchet wheel about the central rotation axis.
  • the indicator includes a gear having teeth on an outer circumference of the gear for engaging the thread of the worm gear.
  • the indicator further includes a pointer attached to the gear for indicating a dose number on a scale on a front surface of the counter body.
  • the counter body is attached to the sleeve by the following mechanism.
  • the sleeve includes a tab and the counter body defines a first recess for receiving the tab of the sleeve.
  • the first recess defines a slot for slideably receiving the tab of the sleeve.
  • the counter body further includes a clip and the sleeve further defines a second recess for receiving the clip of the counter body.
  • the clip is constructed such that the clip can be disabled or detached from the second recess by an unlocking means, which is a key feature, preferably on an inner surface of the housing.
  • the key feature can be configured in other ways, such as forming the key feature as a part of the internal and external surface of the housing, e.g., a protrusion of the housing wall.
  • the key feature engages and disables the clip, such that the counter body is slideably movable along the central axis relatively to the canister.
  • the housing defines a recess for receiving and securing the counter body, such that the counter body cannot move relative to the housing, thereby allowing the canister to be movable along the longitudinal axis relatively to the housing and the counter body.
  • the activating means is a pawl mounted on the outer surface of the sleeve.
  • the pawl is adapted to operatively engage the ratchet teeth of the ratchet wheel so as to rotate the ratchet wheel in response to the reciprocal movement of the canister relative to the counter body when the second clip is detached from the sleeve.
  • the scale which is on an outer surface of the counter body, has dosage indicia thereon for use with the counter assembly.
  • the housing includes a window to show the scale.
  • the scale may be printed directly on the window.
  • the pointer registers against the scale to indicate a dosage on the scale.
  • the pawl engages and rotates the ratchet wheel.
  • the worm gear rotates with the ratchet wheel.
  • the worm gear teeth engage the teeth of the gear of the indicator and drives the gear to rotate.
  • the pointer which is attached to a gear, rotates with the gear, and advances one unit on the scale for each reciprocal motion of the canister. Thereby, the dose counter assembly counts one dose used by the user.
  • the gear includes dosage indicia thereon, which can be digits or other indication means, and a pointer is marked on the counter body.
  • the pointer points to the next digits on the indicia, and thereby, one unit is counted by the dose counter assembly.
  • the dose counter assembly further includes reverse rotation prevention means mounted on the counter body to allow the ratchet wheel to rotate in a predetermined direction and prevent the ratchet wheel from rotating in a direction opposite the predetermined direction.
  • the reverse rotation prevention means preferably is a clip adapted to engage the ratchet teeth of the ratchet wheel.
  • a dose counter assembly in which the resolution of the displayed count is variable or changes so that as the count progresses from a beginning count (when the canister is full) to its final count (when the canister is empty) the resolution improves.
  • the resolution may be continuous, or it may be changed in two or more discrete steps.
  • the resolution of a single counter disk of a dose counter can be improved by using a dual disk arrangement.
  • FIG.l shows a perspective view of an inhaler according to one preferred embodiment of the present invention
  • FIG.2A shows a perspective view of a canister with a sleeve mounted on an outer surface of the canister according to one preferred embodiment of the present invention
  • FIG.2B shows a perspective view of a dose counter assembly mounted on the canister
  • FIG.2C shows a perspective view of the canister with the dose counter assembly received in a housing of the inhaler
  • FIGS.3A shows a front schematic view of the dose counter assembly according to a preferred embodiment of the present invention
  • FIG.3B shows aback schematic view of the dose counter assembly according to a preferred embodiment of the present invention
  • FIG.3 C shows a side schematic view of the dose counter assembly according to a preferred embodiment of the present invention
  • FIG.4A shows a perspective view of the dose counter assembly according to another preferred embodiment of the present invention
  • FIG.4B shows a cross-sectional view of the counter body together with the sleeve according to one preferred embodiment of the present invention
  • FIG.5 shows a key feature on an inner surface of the housing of the inhaler according to one preferred embodiment of the present invention
  • FIG.6 shows a side view of the counter assembly together with the canister according to a preferred embodiment of the present invention
  • FIG.7 shows a scale for use with the dose counter assembly according to one preferred embodiment of the present invention
  • FIG.7 A shows a rotating wheel with numbers thereon for use with the dose counter assembly according to another preferred embodiment of the present invention
  • FIG.7B shows a static pointer readout for use with the dose counter assembly according to yet another preferred embodiment of the present invention.
  • FIGS.8A and 8B illustrate reverse rotation prevention means mounted on the dose counter assembly according to a preferred embodiment of the present invention.
  • FIGS. 9A-9E show side schematic views sequentially illustrating the relative movement of parts of a multi-resolution gauge dose counter assembly providing a resolution that varies continuously or in one or more discrete steps as the counter progresses from its start and final positions;
  • FIG. 10 shows a front perspective, schematic view of a preferred embodiment of a dual disk counter assembly providing greater resolution;
  • FIG. 11 shows the front surface of the front disk of the FIG. 10 embodiment
  • FIG. 12 shows a detail of the front disk of the FIG. 10 embodiment
  • FIG. 13 illustrates a partial perspective view of the dual disk counter assembly of FIG. 10 showing details of the gear and the interrelationship of the front and back disks of the FIG. 10 embodiment
  • FIG. 14 shows a perspective, schematic view of the back surface on the inside of the counter body of the embodiment shown in FIG. 10;
  • FIGS. 15A-15F show frontal schematic views illustrating sequentially the relative movement of the two disks
  • the inhaler 110 includes a housing 112 disposed about a longitudinal axis A with a mouthpiece section 114 at one end and an end cap 116 at the other end, a canister 120 extending along a central axis B, and a dose counter assembly 130 mounted on the canister 120.
  • the canister 120 is received within the housing 112, where the central axis B of the canister 120 is substantially coaxial with the longitudinal axis A of the housing 112 as shown in FIG.2C.
  • the canister 120 is reciprocally moveable along the longitudinal axis A of the housing 112.
  • the canister 120 can be a known type of aerosol dispensing canister in the art, which generally has a cylindrical shape.
  • the aerosol dispensing canister 120 has a stem 121 which contains an aerosol dispensing valve (not shown).
  • the inhaler 110 embodying the present invention can be a breath actuation inhaler or pressure actuation inhaler (pressing the canister to deliver the medicament).
  • a patient's pressing downward at the cap 116 or inhalation at the mouthpiece 114 causes the canister 120 to move downward to an activated position, resulting in the release of a measured dose of medicament through the dispensing nozzle and into the mouthpiece at the same time as the patient breathes in.
  • the canister 120 then returns to a rest position.
  • Both actuation mechanisms can be used in the inhaler 110 embodying the present invention and both are known in the art, and are not described in detail in the present disclosure.
  • the canister 120 includes a sleeve 122, which has an annular shape and is mounted on an outer surface of the canister 120.
  • the dose counter assembly 130 is attached to an outer surface of the sleeve 122.
  • FIG.2C shows the canister 120 with the dose counter assembly 130 is received within the housing 112.
  • FIG.3 A shows a front view
  • FIG.3B shows a back view
  • FIG.3C shows a side view of the dose counter assembly 130.
  • the dose counter assembly 130 includes a counter body 132 adapted to be attached to the outer surface of the sleeve 122, a ratchet wheel 140 rotatably mounted on the counter body 132, a worm gear 146 fixedly mounted on the ratchet wheel 140 and being rotatable with the ratchet wheel 140, an indicator 150 rotatably mounted on the counter body 132, and activating means 126 mounted on the outer surface of the sleeve 122.
  • the ratchet wheel 140 is rotatable about a central rotation axis C and has ratchet teeth 142 on an outer circumference of the ratchet wheel 140.
  • the worm gear 146 has threads 148 on an outer surface of the worm gear 146.
  • the worm gear 146 is rotatable with the ratchet wheel 140 about the central rotation axis C.
  • the indicator 150 includes a gear 152 having teeth on an outer circumference for engaging the threads 148 of the worm gear 146.
  • the indicator 150 further includes a pointer 156 attached to the gear 152 for indicating a dose number on a scale 154 on front surface of the counter body 132.
  • the counter body 132 is attached to the sleeve 122 by the mechanism described below.
  • the sleeve 122 includes at least one tab 133 and the counter body 132 defines at least one recess (hereinafter referred to as a first recess 134) for receiving the tab 133.
  • the sleeve 122 further defines at least one recess
  • FIG.4B shows a cross-sectional view of the sleeve 122 together with the counter body 132 taken along a plane perpendicular to the central axis B.
  • the sleeve 122 includes alignment means, which preferably are two protrusions 144 extending along side walls of the sleeve 122 and the counter body 132 defines two elongated channels 146 for receiving the elongated protrusions 144, such that the sleeve 122 is slideably movable relatively to the counter body 132, but cannot rotate with respect to the counter body 132.
  • the protrusions 144 and the elongated channels 146 maintain the correct alignment of the counter body 132 with the sleeve 122 when the counter body 132 is attached to the sleeve 122.
  • the counter body and canister are constructed so that the counter body can progressively move through its count when positioned in and used with the housing, but will be unable to advance in its counts when the canister and counter body are removed from the housing. This will prevent unintentional misuse and miscounting when in fact no drag is being released.
  • the first recess 134 on the counter body 132 defines a slot for slideably receiving the tab 133 of the sleeve 122.
  • the clip 136 on the sleeve 122 is constructed such that the clip 136 can be disabled or detached from the second recess 135 on the counter body 132 by an unlocking means, which preferably is a key feature 138 on an inner surface of housing 112 as shown in FIG.5. While the key feature is shown on an inner surface of housing 112, the key feature can be configured in other ways, such as forming the key feature as a part of the internal and external surface of the housing, e.g., a protrusion of the housing wall.
  • the key feature 138 engages and disables the clip 136, such that the counter body 132 is slideably movable along the central axis B relative to the canister 120.
  • the housing defines a recess 139 for receiving and securing the counter body 132, such that the counter body 132 cannot move relatively to the housing 112, thereby allowing the canister 120 to be slideably movable along the longitudinal axis A relatively to the housing 112 and the counter body 132.
  • FIG.6 shows a side view of the counter assembly 130 (without the counter body 132) together with the canister 120.
  • the activating means is a pawl 126 mounted on the outer surface of the sleeve 122.
  • the pawl 126 is adapted to operatively engage the ratchet teeth 142 of the ratchet wheel 140 so as to rotate the ratchet wheel 140 in response to the reciprocal movement of the canister 120 relative to the counter body 132 when the second clip 136 is detached from the sleeve 122.
  • FIG.7 illustrates the scale 154 having dosage indicia thereon for use with the counter assembly 130.
  • the scale is on the outer surface of the counter body 132.
  • the housing 112 includes a window to show the scale 154.
  • the scale 154 can be printed on the window.
  • the pointer 156 registers against the scale 154 to indicate a dosage on the scale 154.
  • the pawl 126 engages and rotates the ratchet wheel 140.
  • the worm gear 146 rotates with the ratchet wheel 140.
  • the threads 148 on the worm gear 146 engages the teeth of the gear 152 of the indicator and drives the gear 152 to rotate.
  • the pointer 156 which is attached to gear 152, rotates with the gear 152, and advances one unit on the scale 154. Thereby, the dose counter assembly 130 counts one dose used by the user.
  • the gear 152 may include dosage indicia thereon, which can be digits or other indication means as shown in FIGS.7A and 7B, and a pointer is marked on the counter body 132.
  • dosage indicia thereon
  • FIGS.7A and 7B digits or other indication means as shown in FIGS.7A and 7B
  • a pointer is marked on the counter body 132.
  • the gear 152 is driven to rotate by one step, the pointer points to the next digit on the indicia, and thereby one unit is counted by the dose counter assembly 130 with each dose.
  • Other indication mechanisms are described herein..
  • the dose counter assembly 130 further includes reverse rotation prevention means 145 mounted on the counter body 132 to allow the ratchet wheel 140 to rotate in a predetermined direction and prevent the ratchet wheel from rotating in a direction opposite the predetermined direction.
  • the reverse rotation prevention means 145 preferably is a clip adapted to engage the ratchet teeth 142 of the ratchet wheel 140.
  • the counter can be designed to provide a variable or changing resolution as the counter progresses from a beginning count (when the canister is full) to its final count (when the canister is empty).
  • a coarser resolution at the beginning of the count is not as important as providing a greater resolution as the counter nears it final count. This enables the patient to clearly determine that the canister in use is nearly empty, and will enable to patient to obtain a new canister to replace the old once the use of the current canister is done.
  • FIGS. 9A-9E An example of a multi-resolution gauge dose counter assembly is shown in FIGS. 9A-9E at 160.
  • the assembly 160 is similar to the assembly 130 of FIGS.
  • the ratchet wheel 162 is provided with two intersecting cam slots 166 and 168 which interact with the stationary pins 170 and 172, the latter being attached to the counter body (not shown in FIGS. 9A and 9E).
  • the sequence of rotation of the ratchet wheel 162 is seen to provide a greater radial displacement as the counter approaches its final count.
  • the scale (not shown) which is used with the indicator 164 to indicate the dose can provide indicia markings that are greater apart for counts near the final count.
  • the two slots can be shaped in any workable manner so as to define the resolution with each count.
  • the resolution can vary continuously or in one or more discrete steps.
  • the resolution of the counter of the type shown in FIGS. 7A- 7C can be improved by utilizing more than one disk.
  • indicia markings which would be placed on one disk in the embodiment of FIGS. 7A-7C, are provided on two disks 180 and 182 so that the radial displacement from the beginning count to the end count can actually occur with a radial displacement of more that 360°, thus allowing for a greater radial displacement between each indicia marking.
  • the front disk 180 includes an arcuate slot 184 so that indicia on the rear disk 182 can be viewed.
  • the disks are mounted to interact so that the rear disk is view from the beginning count to a predetermined intermediate count.
  • the rear disk 182 will rotate while the front disk 180 will remain stationary until the count progresses to some intermediate count (the last count for the rear disk).
  • the rear disk 182 will engage the front disk 180 so that the two will rotate together, so that the indicia on the front disk will now come into view.
  • the two disks will continue to rotate with each count until the counter comes to its final count.
  • An illustration of the sequence of movement of the two disks 180 and 182 is shown in FIGS. 15A-15F.
  • FIGS. 11-14 illustrate an example of how the rear disk can freely rotate relative to the front disk from the beginning count to the intermediate count, and engage the front disk at the intermediate count so that the two will rotate together until the final count.
  • the front disk 180 is provided with a circular slot 186
  • the rear disk 182 is provided with driving teeth 188 that is slidable in the slot 186.
  • the slot 186 and driving tooth 188 are position on the disks so that the driving tooth 188 freely slides in the slot 186 between the beginning count and the intermediate count.
  • the driving tooth 188 reaches the end of the slot 186 so that the front disk will begin to rotate with the rear disk until the end position.
  • the rear disk 182 is preferably provided with gear teeth 190 on its periphery, which is driven by the worm gear (not shown).
  • the front disk is not provided with teeth so that it will not rotate until the rear disk reaches a position corresponding to the intermediate count.
  • a bump stop or clip 192 (best seen in FIG. 12), for example, can be provided so as to interact with each individual bump arranged in a circular configuration 194 on the inside of the counter body, indicated at 196 in FIG. 14).
  • the bump stop 192 will engage a bump stop of circular configuration 194 as the rear disk rotates from a position corresponding to the beginning count to a position corresponding to the intermediate count.
  • Driving tooth 188 will then reach the end of the slot 186.
  • sufficient radial force will be transferred from the worm gear to the rear disk, and from the rear disk to the front disk so that the front and rear disks will rotate together and advance one count wherein the bump stop 192 will advance one bump stop of the circular configuration 194.

Abstract

La présente invention concerne un dispositif compteur de doses destiné à être utilisé avec un inhalateur et comprenant un compartiment entourant un axe longitudinal et une cartouche s'étendant le long d'un axe central. Le dispositif compteur de doses comprend un corps de compteur fixé à une surface extérieure de la cartouche, le corps de compteur pouvant se déplacer de manière coulissante le long de l'axe central par rapport à la cartouche, une roue à rochet montée sur le corps de compteur, un engrenage à vis sans fin monté sur la roue à rochet, un indicateur monté rotatif sur le corps de compteur, cet indicateur comprenant un engrenage destiné à entrer en prise avec l'engrenage vis sans fin, et un organe d'actionnement monté sur une surface extérieure de la cartouche en vue d'un engrènement fonctionnel avec les dents triangulaires, ce qui permet de faire tourner la roue à rochet en réponse au mouvement de la cartouche par rapport au corps de compteur. La roue à rochet entraîne l'engrenage à vis sans fin en rotation, ledit engrenage à vis sans fin entraînant à son tour l'indicateur en rotation, d'où le comptage d'une dose distribuée à partir de la cartouche.
PCT/GB2006/002808 2005-07-27 2006-07-27 Dispositif indicateur de compte de type jauge supporte sur cartouche pour inhalateur-doseur WO2007012861A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0515478A GB2429167A (en) 2005-07-27 2005-07-27 Counting mechanism for inhaler
GB0515478.6 2005-07-27

Publications (1)

Publication Number Publication Date
WO2007012861A1 true WO2007012861A1 (fr) 2007-02-01

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Cited By (6)

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EP2436414A3 (fr) * 2010-05-18 2012-08-08 Ivax Pharmaceuticals Ireland Compteurs de doses pour inhalateurs, inhalateurs et gaines associées
US9202164B2 (en) 2011-09-26 2015-12-01 Trudell Medical International Dose counter and medication delivery device
WO2016059645A1 (fr) * 2014-10-14 2016-04-21 Cadila Healthcare Limited Compteur de doses
CN108495680A (zh) * 2016-08-24 2018-09-04 宁波海灵康医药科技有限公司 由上锁功能和计数器组成的吸入喷雾器
CN109621110A (zh) * 2019-01-28 2019-04-16 宁波睿爱产品设计有限公司 一种吸入器用的剂量计数组件
CN111902180A (zh) * 2018-01-31 2020-11-06 新达专业制造私人有限公司 吸入器剂量计量器

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