WO2007019519B1 - Dual-channel pump cartridge and pump for dialysis use - Google Patents

Dual-channel pump cartridge and pump for dialysis use

Info

Publication number
WO2007019519B1
WO2007019519B1 PCT/US2006/030923 US2006030923W WO2007019519B1 WO 2007019519 B1 WO2007019519 B1 WO 2007019519B1 US 2006030923 W US2006030923 W US 2006030923W WO 2007019519 B1 WO2007019519 B1 WO 2007019519B1
Authority
WO
WIPO (PCT)
Prior art keywords
input
output
channel
ring
pump
Prior art date
Application number
PCT/US2006/030923
Other languages
French (fr)
Other versions
WO2007019519A3 (en
WO2007019519A2 (en
Inventor
Victor Gura
Edmond Rambod
Original Assignee
Nat Quality Care Inc
Victor Gura
Edmond Rambod
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nat Quality Care Inc, Victor Gura, Edmond Rambod filed Critical Nat Quality Care Inc
Priority to MX2008001771A priority Critical patent/MX2008001771A/en
Priority to JP2008525282A priority patent/JP2009502446A/en
Priority to BRPI0614083-1A priority patent/BRPI0614083A2/en
Priority to CN2006800359573A priority patent/CN101291704B/en
Priority to EP06800983.6A priority patent/EP1919550B1/en
Publication of WO2007019519A2 publication Critical patent/WO2007019519A2/en
Publication of WO2007019519A3 publication Critical patent/WO2007019519A3/en
Publication of WO2007019519B1 publication Critical patent/WO2007019519B1/en
Priority to HK09103722.0A priority patent/HK1125322A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
    • A61M1/1694—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes with recirculating dialysing liquid
    • A61M1/1696—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes with recirculating dialysing liquid with dialysate regeneration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
    • A61M1/1621—Constructional aspects thereof
    • A61M1/1645—Constructional aspects thereof with mechanically linked peristaltic dialysis fluid pumps one upstream, the other one downstream of the dialyser
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/34—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
    • A61M1/3472—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration with treatment of the filtrate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3672—Means preventing coagulation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/10—Location thereof with respect to the patient's body
    • A61M60/104—Extracorporeal pumps, i.e. the blood being pumped outside the patient's body
    • A61M60/109—Extracorporeal pumps, i.e. the blood being pumped outside the patient's body incorporated within extracorporeal blood circuits or systems
    • A61M60/113—Extracorporeal pumps, i.e. the blood being pumped outside the patient's body incorporated within extracorporeal blood circuits or systems in other functional devices, e.g. dialysers or heart-lung machines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/20—Type thereof
    • A61M60/247—Positive displacement blood pumps
    • A61M60/253—Positive displacement blood pumps including a displacement member directly acting on the blood
    • A61M60/268—Positive displacement blood pumps including a displacement member directly acting on the blood the displacement member being flexible, e.g. membranes, diaphragms or bladders
    • A61M60/279—Peristaltic pumps, e.g. roller pumps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/30—Medical purposes thereof other than the enhancement of the cardiac output
    • A61M60/36—Medical purposes thereof other than the enhancement of the cardiac output for specific blood treatment; for specific therapy
    • A61M60/38—Blood oxygenation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/40—Details relating to driving
    • A61M60/424—Details relating to driving for positive displacement blood pumps
    • A61M60/438—Details relating to driving for positive displacement blood pumps the force acting on the blood contacting member being mechanical
    • A61M60/441—Details relating to driving for positive displacement blood pumps the force acting on the blood contacting member being mechanical generated by an electromotor
    • A61M60/443—Details relating to driving for positive displacement blood pumps the force acting on the blood contacting member being mechanical generated by an electromotor with means converting the rotation into a translational movement of the displacement member
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/80—Constructional details other than related to driving
    • A61M60/845—Constructional details other than related to driving of extracorporeal blood pumps
    • A61M60/849—Disposable parts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/80—Constructional details other than related to driving
    • A61M60/845—Constructional details other than related to driving of extracorporeal blood pumps
    • A61M60/851—Valves
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
    • F04B43/00—Machines, pumps, or pumping installations having flexible working members
    • F04B43/08—Machines, pumps, or pumping installations having flexible working members having tubular flexible members
    • F04B43/082—Machines, pumps, or pumping installations having flexible working members having tubular flexible members the tubular flexible member being pressed against a wall by a number of elements, each having an alternating movement in a direction perpendicular to the axes of the tubular member and each having its own driving mechanism
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
    • F04B43/00—Machines, pumps, or pumping installations having flexible working members
    • F04B43/08—Machines, pumps, or pumping installations having flexible working members having tubular flexible members
    • F04B43/086—Machines, pumps, or pumping installations having flexible working members having tubular flexible members with two or more tubular flexible members in parallel
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
    • F04B43/00—Machines, pumps, or pumping installations having flexible working members
    • F04B43/08—Machines, pumps, or pumping installations having flexible working members having tubular flexible members
    • F04B43/09—Pumps having electric drive
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/33—Controlling, regulating or measuring
    • A61M2205/3379—Masses, volumes, levels of fluids in reservoirs, flow rates
    • A61M2205/3389—Continuous level detection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/82—Internal energy supply devices
    • A61M2205/8206—Internal energy supply devices battery-operated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/82—Internal energy supply devices
    • A61M2205/8206—Internal energy supply devices battery-operated
    • A61M2205/8212—Internal energy supply devices battery-operated with means or measures taken for minimising energy consumption
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/82—Internal energy supply devices
    • A61M2205/8237—Charging means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2209/00—Ancillary equipment
    • A61M2209/08—Supports for equipment
    • A61M2209/088—Supports for equipment on the body

Abstract

A dual channel pulsatile pump for use with a completely wearable renal replacement device is provided.

Claims

AMENDED CLAIMS received by the International Bureau on 21 May 2007 (21.05.07)What is claimed Is;
1. A dual channel pulsatile pump comprising: a dual channel pump cartridge having a first channel and a second channel, each channel of said dual channel pump cartridge comprising: a peristaltic tube that is compressible, said peristaltic tube having an input end and an output end;
an input valve at the input end, said input valve comprising an input o-ring, an input ball thai seats against said input o-ring to stop fluid back flowihrough said input valve and an input spring member that positions said input ball against said input o-ring when the peristaltic tube is being compressed, said input spring member allows said input ball Io move away from said input o-ring and allow forward fluid flow through said input valve when said peristaltic tube is being allowed to decompress , said input spring member comprises: an outer .ring naving a first diameter; an inner ring having a second diameter that is smaller than said first diameter; and a least two and not more than three spokes extending radially from said inner ring to said outer ring; said inner ring being able to move laterally with respect to aplane extending perpendicular to an axis of said outer ring; an output valve at said output end, said output valve comprising an output o-ring, an output ball that seats against said output .o-τing to stop fluid back flow through said output valve and an output spring member that positions said output ball against said output o-ring when -the peristaltic tube is being decompressed, said output spring member allows said output tall 1o move away from said output o-ring and allow forward fluid flow through said output valve when said peristaltic tube is being compressed; and a pump motor portion comprising -Gist oscillating pushing member for compressing and decompressing said peristaltic tube in. a first channel and a second oscillating pushing member for compressing and decompressing said peristaltic tube in a second channel, said dual channel pump cartridge being removably attachable to said pump motor portion,
2. (Cancelled)
3. The dual channel pulsatile pump of cMm 1, wherein said a dual channel pump cartridge dimensions are less than .72 inches high, 3.82 inches long, and 1.7 inches wide wherein each measurement is plus or minus 50 percent.
4. The dual channel pulsatile .pump of claim 1, wherein 1he dual channel pulsatile pump has dimensions of 9.7 x 7.1 x 4.6 cm and & weight of less than 400 grams plus or minus 50%.
5. The dual channel pulsatile pump of claim 1» wherein said inner ring is a stabilizer of said ball when fluid is flowing through said input -valve.
6. A completely wearable artificial kidney (WAK) device comprising: a blood circuit; a dialysate circuit; a dual channel pulsatile pump comprising; a first channel for pumping the blood through said blood circuit and a second channel for pumping dialysate through said dialysate circuit; each of said first channel and said second .channel comprising: aperistaltic tube that is compressible, said peristaltic tube having an input end and an. output end;
an input valve at the input end, said input valve comprising an input o-ring, an input ball 1hat seats against said input o«rmg to stop fluid back flow through said input valve and an input spring member that positions said input ball against said input o-ring when ihe peristaltic .tube is being compressed, said input spring member allows said input ball to move away from said input o-ring and allow forward fluid flowthrough said input valve -when said peristaltic tube is being allowed to decompress, said input spring member comprises: an outer ring having a first diameter; an inner ring having a second diameter raatis smaller than said first diameter; and a least two and not more than three spokes extending radially from said inner ting to said outer ring; said inner ring being able to move laterally withxespectto a plane extending perpendicular to an axis of said outer ring; and an output valve at said output end, said output valve comprising an output o-ring9 an output ball that seats against said output o-τing to stop fluid back flow through said output valve and an output spring member that positions said output ball against said output o-dng when the peristaltic tube is being decompressed, said output spring member allows said output ball to move away from said output o-ring and allow forward fluid flow through said output valve when said peristaltic tube is being compressed; and a single electric motor and transmission that alternately compresses and decompress the peristaltic tube in said -first channel and said peristaltic tube in said second channel; said dialysate circuit, said blood circuit, and said a dual channel pulsatile pump all being completely worn by said user.
7- The completely wearable artificial Mdney (WAK) device of claim 6, wherein said dual channel pulsatile pump provides a blood flow rate through said blood circuit of between 15 and 100 ml/min pulsatile.
S. The completely wearable artificial kidney (WAK) device of claim 6, wherein said dual channel pulsatile pump provides alternating pulses in the first and the second channels that are 180 degrees out of phase.
9, The completelywearable artificial Mdney (WAK) device of claim 6, wherein said dual channel pulsatile pump can pump from 0 to 350 ml/min of blood in said blood circuit.
10. The completely wearable artificial Jάdney (WAK) device of claim 6, wherein said dual channel pulsatile pump can pump tx>m 0 to 350 nd/min of and dialysate in the dialysate circuit.
11. A completely wearable artificial Jkidney (WAK) device comprising: a blood circuit; a dialysate circuit; and a dual channel pulsatile pump comprising; a first channel for pumping blood through said blood circuit and a second channel for pumping dialysate through said dialysate circuit, said first channel and said second ^channel providing pump cycles that are out of phase; said first channel comprises: a peristaltic tube mat is compressible, said peristaltic tube having an input end and an output end;
an input valve at the input end, said input valve comprising an input ball seat, an input ball that seats against said input ball seat 1o stop ftuid back flow through said input valve and an input spring member that positions said input ball against said input ball seat when the peristaltic tube is being compressed, said input spring member comprises:
an outer ring tiaving & first diameter; an inner ring having a second diameter that is smaller than said first diameter; and a least two and not more than three spokes extending radially from said inner ring 1o said outer ring; said inner ring being able to amove laterally "with respect toa plane extejidingpeipendicular to an axis of said outer ring; said input spring member allows said input ball to move away jBrom said ϊnputball seat and allows forward fluid flow through said input valve when said peristaltic tube is being allowed to decompress; and an output valve at said output end.
12. The completely wearable .artificial Mdney (WAK) device of claim 11, wherein the first and second pump cycles are 180 degrees out of phase.
13. The completely wearable artificial kidney (WAK) device of claim 11, further comprising a dialyzer, said dialyzer being in said blood circuit and in said dialysate circuit such that .the blood and dialysate pass through the dialyzer in opposing directions.
14. (Canceled)
15. The completely wearable artificial Mdney ,(WAK) device of claim. 11, further comprising a pH control system that keeps ihe pH of the dialysate Bt Ά predetermined pH.
16. The completely wearable artificial Sidney (WAK) device of claim 11, wherein said WAK provides hemodialGltratioii and not purely hemodialysis.
AMENDED 77HEET (ARTICLE 19)
PCT/US2006/030923 2005-08-05 2006-08-07 Dual-channel pump cartridge and pump for dialysis use WO2007019519A2 (en)

Priority Applications (6)

Application Number Priority Date Filing Date Title
MX2008001771A MX2008001771A (en) 2005-08-05 2006-08-07 Dual-channel pump cartridge and pump for dialysis use.
JP2008525282A JP2009502446A (en) 2005-08-05 2006-08-07 Dual channel pump cartridge and dialysis pump
BRPI0614083-1A BRPI0614083A2 (en) 2005-08-05 2006-08-07 dual channel pulsating pump and fully portable artificial kidney device (rap)
CN2006800359573A CN101291704B (en) 2005-08-05 2006-08-07 Dual-channel pump cartridge and pump, use method in wearable continuous kidney replacement therapy device
EP06800983.6A EP1919550B1 (en) 2005-08-05 2006-08-07 Dual-channel pump for dialysis use
HK09103722.0A HK1125322A1 (en) 2005-08-05 2009-04-22 Dual-channel pump cartridge and pump for dialysis use

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US70616705P 2005-08-05 2005-08-05
US60/706,167 2005-08-05

Publications (3)

Publication Number Publication Date
WO2007019519A2 WO2007019519A2 (en) 2007-02-15
WO2007019519A3 WO2007019519A3 (en) 2007-06-07
WO2007019519B1 true WO2007019519B1 (en) 2007-07-19

Family

ID=37728004

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2006/030923 WO2007019519A2 (en) 2005-08-05 2006-08-07 Dual-channel pump cartridge and pump for dialysis use

Country Status (8)

Country Link
US (2) US7854718B2 (en)
EP (1) EP1919550B1 (en)
JP (1) JP2009502446A (en)
CN (1) CN101291704B (en)
BR (1) BRPI0614083A2 (en)
HK (1) HK1125322A1 (en)
MX (1) MX2008001771A (en)
WO (1) WO2007019519A2 (en)

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