WO2007033353A3 - Chemical target-binding compositions - Google Patents

Chemical target-binding compositions Download PDF

Info

Publication number
WO2007033353A3
WO2007033353A3 PCT/US2006/035968 US2006035968W WO2007033353A3 WO 2007033353 A3 WO2007033353 A3 WO 2007033353A3 US 2006035968 W US2006035968 W US 2006035968W WO 2007033353 A3 WO2007033353 A3 WO 2007033353A3
Authority
WO
WIPO (PCT)
Prior art keywords
chemical target
concentration
ecosystem
chemical
target
Prior art date
Application number
PCT/US2006/035968
Other languages
French (fr)
Other versions
WO2007033353A2 (en
Inventor
George Y Daniloff
Original Assignee
Therabit Inc
George Y Daniloff
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Therabit Inc, George Y Daniloff filed Critical Therabit Inc
Publication of WO2007033353A2 publication Critical patent/WO2007033353A2/en
Publication of WO2007033353A3 publication Critical patent/WO2007033353A3/en
Priority to US12/047,076 priority Critical patent/US20080200434A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings

Abstract

Herein in described compositions and methods for modulating and regulating the concentration of a chemical target in an organism or in an ecosystem. In one embodiment, the concentration is regulated such that it is maintained below or above a certain threshold, thus avoiding toxic or harmful effects of the chemical target. The described compositions may, for example, be implanted in a human body or placed in the ecosystem. The compositions comprise binding moieties that reversibly bind to a chemical target in the organism or ecosystem. The binding capacity and the binding constants for a chemical target are designed such that the composition maintains the concentration of the chemical target substantially within a beneficial range of concentration.
PCT/US2006/035968 2005-09-14 2006-09-14 Chemical target-binding compositions WO2007033353A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
US12/047,076 US20080200434A1 (en) 2006-09-14 2008-03-12 Chemical Target-Binding Compositions

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US59630005P 2005-09-14 2005-09-14
US60/596,300 2005-09-14

Publications (2)

Publication Number Publication Date
WO2007033353A2 WO2007033353A2 (en) 2007-03-22
WO2007033353A3 true WO2007033353A3 (en) 2007-10-11

Family

ID=37865594

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2006/035968 WO2007033353A2 (en) 2005-09-14 2006-09-14 Chemical target-binding compositions

Country Status (1)

Country Link
WO (1) WO2007033353A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20230044696A1 (en) * 2021-07-20 2023-02-09 Ut-Battelle, Llc Dynamically crosslinked tough adhesive with recyclability

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6485703B1 (en) * 1998-07-31 2002-11-26 The Texas A&M University System Compositions and methods for analyte detection
US6627177B2 (en) * 2000-12-05 2003-09-30 The Regents Of The University Of California Polyhydroxyl-substituted organic molecule sensing optical in vivo method utilizing a boronic acid adduct and the device thereof
US20050095636A1 (en) * 2003-07-16 2005-05-05 Warner Benjamin P. Method and apparatus for detecting chemical binding

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6485703B1 (en) * 1998-07-31 2002-11-26 The Texas A&M University System Compositions and methods for analyte detection
US6627177B2 (en) * 2000-12-05 2003-09-30 The Regents Of The University Of California Polyhydroxyl-substituted organic molecule sensing optical in vivo method utilizing a boronic acid adduct and the device thereof
US20050095636A1 (en) * 2003-07-16 2005-05-05 Warner Benjamin P. Method and apparatus for detecting chemical binding

Also Published As

Publication number Publication date
WO2007033353A2 (en) 2007-03-22

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