WO2007050671A3 - Fermentive production of four carbon alcohols - Google Patents
Fermentive production of four carbon alcohols Download PDFInfo
- Publication number
- WO2007050671A3 WO2007050671A3 PCT/US2006/041602 US2006041602W WO2007050671A3 WO 2007050671 A3 WO2007050671 A3 WO 2007050671A3 US 2006041602 W US2006041602 W US 2006041602W WO 2007050671 A3 WO2007050671 A3 WO 2007050671A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- carbon alcohols
- fermentive production
- production
- fermentive
- isobutanol
- Prior art date
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
- C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
- C12P7/16—Butanols
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/70—Vectors or expression systems specially adapted for E. coli
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
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- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
- C12N15/746—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for lactic acid bacteria (Streptococcus; Lactococcus; Lactobacillus; Pediococcus; Enterococcus; Leuconostoc; Propionibacterium; Bifidobacterium; Sporolactobacillus)
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- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
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- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
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- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
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- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0012—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7)
- C12N9/0014—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on the CH-NH2 group of donors (1.4)
- C12N9/0016—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on the CH-NH2 group of donors (1.4) with NAD or NADP as acceptor (1.4.1)
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- C12N9/1022—Transferases (2.) transferring aldehyde or ketonic groups (2.2)
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- C12Y101/00—Oxidoreductases acting on the CH-OH group of donors (1.1)
- C12Y101/01—Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
- C12Y101/01001—Alcohol dehydrogenase (1.1.1.1)
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- C12Y101/00—Oxidoreductases acting on the CH-OH group of donors (1.1)
- C12Y101/01—Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
- C12Y101/01002—Alcohol dehydrogenase (NADP+) (1.1.1.2), i.e. aldehyde reductase
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- C12Y101/00—Oxidoreductases acting on the CH-OH group of donors (1.1)
- C12Y101/01—Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
- C12Y101/01086—Ketol-acid reductoisomerase (1.1.1.86)
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- C12Y102/00—Oxidoreductases acting on the aldehyde or oxo group of donors (1.2)
- C12Y102/04—Oxidoreductases acting on the aldehyde or oxo group of donors (1.2) with a disulfide as acceptor (1.2.4)
- C12Y102/04004—3-Methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) (1.2.4.4), i.e. branched-chain-alpha-ketoacid dehydrogenase
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- C12Y202/00—Transferases transferring aldehyde or ketonic groups (2.2)
- C12Y202/01—Transketolases and transaldolases (2.2.1)
- C12Y202/01006—Acetolactate synthase (2.2.1.6)
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- C12Y—ENZYMES
- C12Y401/00—Carbon-carbon lyases (4.1)
- C12Y401/01—Carboxy-lyases (4.1.1)
- C12Y401/01072—Branched-chain-2-oxoacid decarboxylase (4.1.1.72)
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- C12Y402/00—Carbon-oxygen lyases (4.2)
- C12Y402/01—Hydro-lyases (4.2.1)
- C12Y402/01009—Dihydroxy-acid dehydratase (4.2.1.9), i.e. acetohydroxyacid dehydratase
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- C12Y102/00—Oxidoreductases acting on the aldehyde or oxo group of donors (1.2)
- C12Y102/01—Oxidoreductases acting on the aldehyde or oxo group of donors (1.2) with NAD+ or NADP+ as acceptor (1.2.1)
- C12Y102/01003—Aldehyde dehydrogenase (NAD+) (1.2.1.3)
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
- Y02E50/00—Technologies for the production of fuel of non-fossil origin
- Y02E50/10—Biofuels, e.g. bio-diesel
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
- Y02E50/00—Technologies for the production of fuel of non-fossil origin
- Y02E50/30—Fuel from waste, e.g. synthetic alcohol or diesel
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/52—Improvements relating to the production of bulk chemicals using catalysts, e.g. selective catalysts
Abstract
Priority Applications (8)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CA2622026A CA2622026C (en) | 2005-10-26 | 2006-10-25 | Fermentive production of four carbon alcohols |
NZ566406A NZ566406A (en) | 2005-10-26 | 2006-10-25 | Fermentive production of four carbon alcohols |
NZ593809A NZ593809A (en) | 2005-10-26 | 2006-10-25 | Fermentive production of four carbon alcohols |
MX2016010845A MX359740B (en) | 2005-10-26 | 2006-10-25 | Fermentive production of four carbon alcohols. |
JP2008537902A JP5276986B2 (en) | 2005-10-26 | 2006-10-25 | Fermentative production of four-carbon alcohol |
EP06836518.8A EP1948814B1 (en) | 2005-10-26 | 2006-10-25 | Fermentive production of four carbon alcohols |
BRPI0619325A BRPI0619325B8 (en) | 2005-10-26 | 2006-10-25 | recombinant microbial host cell and method for isobutanol production |
EP11154734.5A EP3301182B1 (en) | 2005-10-26 | 2006-10-25 | Fermentative production of four carbon alcohols |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US73029005P | 2005-10-26 | 2005-10-26 | |
US60/730,290 | 2005-10-26 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2007050671A2 WO2007050671A2 (en) | 2007-05-03 |
WO2007050671A3 true WO2007050671A3 (en) | 2007-06-21 |
Family
ID=37835200
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2006/041602 WO2007050671A2 (en) | 2005-10-26 | 2006-10-25 | Fermentive production of four carbon alcohols |
Country Status (12)
Country | Link |
---|---|
US (14) | US7851188B2 (en) |
EP (2) | EP3301182B1 (en) |
JP (1) | JP5276986B2 (en) |
CN (1) | CN101297042A (en) |
BR (1) | BRPI0619325B8 (en) |
CA (1) | CA2622026C (en) |
MX (2) | MX359740B (en) |
NZ (2) | NZ566406A (en) |
RU (1) | RU2394913C2 (en) |
UA (3) | UA96928C2 (en) |
WO (1) | WO2007050671A2 (en) |
ZA (1) | ZA200803755B (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9410166B2 (en) | 2009-12-29 | 2016-08-09 | Butamax Advanced Biofuels Llc | Alcohol dehydrogenases (ADH) useful for fermentive production of lower alkyl alcohols |
US9512435B2 (en) | 2010-02-17 | 2016-12-06 | Butamax Advanced Biofuels Llc | Activity of Fe—S cluster requiring proteins |
Families Citing this family (252)
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US7781191B2 (en) | 2005-04-12 | 2010-08-24 | E. I. Du Pont De Nemours And Company | Treatment of biomass to obtain a target chemical |
US20070029252A1 (en) | 2005-04-12 | 2007-02-08 | Dunson James B Jr | System and process for biomass treatment |
CA2604100C (en) | 2005-04-12 | 2013-04-02 | E. I. Du Pont De Nemours And Company | Integration of alternative feedstreams in biomass treatment and utilization |
US20080274526A1 (en) * | 2007-05-02 | 2008-11-06 | Bramucci Michael G | Method for the production of isobutanol |
US8273558B2 (en) | 2005-10-26 | 2012-09-25 | Butamax(Tm) Advanced Biofuels Llc | Fermentive production of four carbon alcohols |
US9303225B2 (en) * | 2005-10-26 | 2016-04-05 | Butamax Advanced Biofuels Llc | Method for the production of isobutanol by recombinant yeast |
NZ566406A (en) * | 2005-10-26 | 2012-04-27 | Butamax Advanced Biofuels Llc | Fermentive production of four carbon alcohols |
US8945899B2 (en) | 2007-12-20 | 2015-02-03 | Butamax Advanced Biofuels Llc | Ketol-acid reductoisomerase using NADH |
US7309602B2 (en) * | 2006-04-13 | 2007-12-18 | Ambrozea, Inc. | Compositions and methods for producing fermentation products and residuals |
US20090099401A1 (en) | 2006-06-16 | 2009-04-16 | D Amore Michael B | Process for making isooctenes from aqueous isobutanol |
WO2008091627A2 (en) * | 2007-01-22 | 2008-07-31 | Genomatica, Inc. | Methods and organisms for growth-coupled production of 3-hydroxypropionic acid |
MY147186A (en) * | 2007-02-09 | 2012-11-14 | Univ California | Biofuel production by recombinant microorganisms |
US20090111154A1 (en) * | 2007-04-04 | 2009-04-30 | The Regents Of The University Of California | Butanol production by recombinant microorganisms |
EP2134849B1 (en) | 2007-04-18 | 2013-07-10 | Butamax (TM) Advanced Biofuels LLC | Fermentive production of isobutanol using highly active ketol-acid reductoisomerase enzymes |
US8026386B2 (en) * | 2007-08-10 | 2011-09-27 | Genomatica, Inc. | Methods for the synthesis of olefins and derivatives |
US7807419B2 (en) | 2007-08-22 | 2010-10-05 | E. I. Du Pont De Nemours And Company | Process for concentrated biomass saccharification |
US7819976B2 (en) | 2007-08-22 | 2010-10-26 | E. I. Du Pont De Nemours And Company | Biomass treatment method |
US8445236B2 (en) | 2007-08-22 | 2013-05-21 | Alliance For Sustainable Energy Llc | Biomass pretreatment |
MX2010003501A (en) * | 2007-10-04 | 2010-06-09 | Bio Architecture Lab Inc | Biofuel production. |
CN101903530A (en) * | 2007-10-12 | 2010-12-01 | 加利福尼亚大学董事会 | Microorganism engineered to produce isopropanol |
WO2009059254A2 (en) | 2007-10-31 | 2009-05-07 | Gevo, Inc | Methods for the economical production of biofuel precursor that is also a biofuel from biomass |
EP2225351A4 (en) | 2007-12-03 | 2016-11-09 | Gevo Inc | Renewable compositions |
US8193402B2 (en) * | 2007-12-03 | 2012-06-05 | Gevo, Inc. | Renewable compositions |
US8114641B2 (en) | 2007-12-10 | 2012-02-14 | Synthetic Genomics, Inc. | Methylbutanol as an advanced biofuel |
DE102007060705A1 (en) | 2007-12-17 | 2009-06-18 | Evonik Degussa Gmbh | ω-aminocarboxylic acids or their lactams, producing, recombinant cells |
ES2575413T3 (en) | 2007-12-20 | 2016-06-28 | Butamax (Tm) Advanced Biofuels Llc | Cetol-acid reductoisomerase using NADH |
US8518678B2 (en) * | 2007-12-21 | 2013-08-27 | Butamax(Tm) Advanced Biofuels Llc | Strain comprising increased expression of a CFA coding region for butanol production |
US8372612B2 (en) * | 2007-12-21 | 2013-02-12 | Butamax(Tm) Advanced Biofuels Llc | Production of four carbon alcohols using improved strain |
US20090162911A1 (en) * | 2007-12-21 | 2009-06-25 | E.I. Du Pont De Nemours And Company | Strain for butanol production |
US8455239B2 (en) | 2007-12-23 | 2013-06-04 | Gevo, Inc. | Yeast organism producing isobutanol at a high yield |
DK2235193T3 (en) * | 2007-12-23 | 2016-02-29 | Gevo Inc | Yeast organism PRODUCING ISO BUTANOL HIGH DIVIDEND |
KR20100107480A (en) | 2007-12-27 | 2010-10-05 | 게보 인코포레이티드 | Recovery of higher alcohols from dilute aqueous solutions |
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