WO2007052296A3 - A process of preparing amorphous atorvastatin calcium - Google Patents

A process of preparing amorphous atorvastatin calcium Download PDF

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Publication number
WO2007052296A3
WO2007052296A3 PCT/IN2006/000306 IN2006000306W WO2007052296A3 WO 2007052296 A3 WO2007052296 A3 WO 2007052296A3 IN 2006000306 W IN2006000306 W IN 2006000306W WO 2007052296 A3 WO2007052296 A3 WO 2007052296A3
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WO
WIPO (PCT)
Prior art keywords
atorvastatin calcium
amorphous atorvastatin
preparing amorphous
calcium
preparing
Prior art date
Application number
PCT/IN2006/000306
Other languages
French (fr)
Other versions
WO2007052296A2 (en
Inventor
Gupte Rajan Vitthal
Hire Chandrabhan Madhav
Amol Haridas Bhendkar
Original Assignee
Kopran Res Lab Ltd
Gupte Rajan Vitthal
Hire Chandrabhan Madhav
Amol Haridas Bhendkar
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kopran Res Lab Ltd, Gupte Rajan Vitthal, Hire Chandrabhan Madhav, Amol Haridas Bhendkar filed Critical Kopran Res Lab Ltd
Publication of WO2007052296A2 publication Critical patent/WO2007052296A2/en
Publication of WO2007052296A3 publication Critical patent/WO2007052296A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pyrrole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

A simple and economical process for the preparation of amorphous atorvastatin calcium in high purity and good yield from crystalline atorvastatin sodium without forming crystalline atorvastatin calcium is disclosed.
PCT/IN2006/000306 2005-08-23 2006-08-22 A process of preparing amorphous atorvastatin calcium WO2007052296A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN996/MUM/2005 2005-08-23
IN996MU2005 2005-08-23

Publications (2)

Publication Number Publication Date
WO2007052296A2 WO2007052296A2 (en) 2007-05-10
WO2007052296A3 true WO2007052296A3 (en) 2007-11-15

Family

ID=38006307

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IN2006/000306 WO2007052296A2 (en) 2005-08-23 2006-08-22 A process of preparing amorphous atorvastatin calcium

Country Status (1)

Country Link
WO (1) WO2007052296A2 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI22255A (en) * 2006-04-14 2007-10-31 Krka, Tovarna Zdravil, D.D., Novo Mesto New polymorphs of statine salts and their application in pharmaceutical formulations
WO2008053495A1 (en) * 2006-10-30 2008-05-08 Lupin Limited A novel crystalline form of atorvastatin sodium
CN102935076A (en) * 2012-11-29 2013-02-20 康普药业股份有限公司 Capsule containing atorvastatin sodium and preparation method thereof
CN113321607A (en) * 2020-02-28 2021-08-31 北京福元医药股份有限公司沧州分公司 Purification method of atorvastatin calcium intermediate

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000071116A1 (en) * 1999-05-25 2000-11-30 Ranbaxy Laboratories Limited Process for the production of amorphous atorvastatin calcium
WO2002083638A1 (en) * 2001-04-11 2002-10-24 Cadila Healthcare Limited Process for the production of atorvastatin calcium in amorphous form

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000071116A1 (en) * 1999-05-25 2000-11-30 Ranbaxy Laboratories Limited Process for the production of amorphous atorvastatin calcium
WO2002083638A1 (en) * 2001-04-11 2002-10-24 Cadila Healthcare Limited Process for the production of atorvastatin calcium in amorphous form

Also Published As

Publication number Publication date
WO2007052296A2 (en) 2007-05-10

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