WO2007057724A1

WO2007057724A1 - Hollow pin for the creation of frozen zones

Info

Publication number: WO2007057724A1
Application number: PCT/IB2005/003526
Authority: WO
Inventors: Dieter Steinfatt; Helga Steinfatt
Original assignee: Dieter Steinfatt; Helga Steinfatt
Priority date: 2005-11-17
Filing date: 2005-11-17
Publication date: 2007-05-24

Abstract

The invention relates to a hollow pin which is optionally connected to a thermally insulated exhaust gas pipe or tube and is impinged upon by cryogenic gas in order to create frozen zones in tissue. The aim of the invention is to be able to obtain frozen zones of less than -40 °C which are located deep down in the tissue. Said aim is achieved by introducing a hollow pin that is closed on one side and comprises an insulated exhaust gas pipe/tube into the tissue and impinging said hollow pin with liquid cryogenic gas, e.g. N2O, with the aid of a separate mobile feed line. Impinging the hollow pin with liquid N2O having a latent heat of -89 °C creates frozen zones of less than -40 °C in the tissue.

Description

HOLLOW PENCIL FOR THE PRODUCTION OF FREEZING ZONES

description

Conventionally, there are a variety of dosing devices that apply cryogenic gas to tissue in the medical field. This has the consequence that due to the cryogenic gases cryogenic distribution zones are generated in the tissue in that heat is removed from the surrounding tissue, thus this iced. The icing causes when temperatures of more than -40 ⁰ C tissue is present that cells are killed. This is desirable, for example, when cancer cells in the derma are to be eliminated. There is already a great deal of experience with cryogenic gas, for example, to heal skin lesions favorably.

Depending on the given criteria, the technique used can vary between so-called spray freezing, contact freezing or liquid freezing.

In these principles, the tissue zone is acted upon from the outside with cryogenic gas. The efficient technology is certainly the liquid freezing, since the refrigerant consumption is directly close to the theoretically required refrigerant demand. Furthermore, by applying the pure liquid phase, the specific evaporation temperature is constantly available during the therapy. This is necessary in order to achieve reproducible healing results. Practice has now shown that the externally applied effective freezing zone with -40 ⁰ C in the tissue with the application of N ₂ O to max. 3mm depth is enough. When N _{2 is used} , the freezing temperature of -1 96 ° C results in a freezing depth of max. 5mm at -40 ⁰ C. This limits for certain lesions that are far deeper in the tissue, which then did not get the necessary destruction temperature. In order to achieve useful destructions in deeper tissue zones, is in a known Performing similar to an injection cannula deeper into the tissue at the corresponding lesion, the liquid cryogenic gas placed. In the subsequent gas relaxation can lead to straying gas outbreaks, which are not desirable in certain indications and can also cause tissue damage. The object of the invention is therefore to provide a device which can produce destructions on the one hand with liquid cryogenic gas in deep-lying tissue zones, but on the other hand tissue damage is reliably excluded by the expanding gas.

According to the invention the object is achieved in that in the region of the indication zone a one-side open hollow pin (or more) is introduced into the tissue, while the open side is used for filling liquid cryogenic gas. The liquid gas relaxation takes place in the interior of the hollow pin, thereby removing the heat from the adjacent tissue.

Thus the destruction process begins. After the freezing is completed, the hollow pin can be easily removed from the tissue. Thus, the typical freezing effect has failed its effect. The hollow pin is provided on the closed side with a patient-compatible tip. The hollow pin consists of good conductive material and should have a gold coating for reasons of biocompatibility. The hollow pin is sterilizable and reusable. The hollow pin shape is selected according to the requirements made. In nest-like lesions in tissue a hollow pin is connected BEZW with a heat-insulated exhaust pipe. Exhaust hose used to effectively prevent a freezing zone at the Gewebeinstechkanal and sure the relaxed gas is discharged. The loading of the hollow pin via a hand-guided supply line. This may be, for example, a stainless steel capillary which places the cryogenic gas within the hollow pin and then immediately withdrawn. The gas release takes place via the insulated exhaust pipe BEZW. via the insulated hose line into the atmosphere. In the drawing No. 1, the position of the hollow pin is shown so that its open side is in contact with the surrounding atmosphere and protrudes slightly out of the tissue. Via the gas source 3, the liquid cryogenic gas is introduced through the opening of the valve 4 through the microcapillary into the hollow pin. After reaching the desired freezing result, the valve is closed and the microcapillary pulled out. During the application of liquid cryogenic gas, the gas relaxation and this takes place in the atmosphere, between the free space of the hollow pin and the microcapillary derived. The drawing no. 2 shows the possibility to produce freezer in low-lying tissue. Here, with the help of the heat-insulating Abgasrohres- or exhaust hose Pos. 8 prevents a possible freezing effect on the fabric by the derived expanded gas and this controlled in the atmosphere derived. In order to be able to monitor this destruction process, the hollow pin can be connected with an insulating tube or tube to an endoscopy and temperature control device to be brought to the lesion.

Claims

claims

1 . Concerns the claim of a hollow pin for the freezing of tissue in the medical field, which is implanted in the tissue for a short time during the freezing phase, characterized in that it unilaterally has a closed tip and can be acted upon from its open side with liquid cryogenic gas.

2. Claim 1 characterized in that the hollow pin consists of a good heat conducting material, preferably of copper and a very thin lateral surface thickness not more than 0, 1 mm.

3. claim according to 1 and 2, characterized in that the hollow pin is connected to an insulated Abgasrohr- or exhaust hose to produce low in tissue Gefriernester, by this a freezing effect of the same on the tissue is prevented, but effectively controls the gas relaxation back into the Atmosphere secures.

4. Claim according to 1, 2 and 3, characterized in that the hollow pin is designed according to the application of certain lesions in appropriate form and unhindered over the isolated exhaust pipe or insulated exhaust hose from a source via a e.g. Flexible stainless steel micro capillary can be acted upon with liquid cryogenic gas.

5. Claim 1, 2, 3 and 4, characterized in that the hollow pin is preferably made of copper, has a gold coating in order to meet the Bikompatibilität.

6. Claim according to 1, characterized in that the hollow pin is connected together with an endoscopy device and a Temperaturmeßeinheit to monitor the destruction process in the zone to be treated can.