WO2007075378A2

WO2007075378A2 - Control systems for individualized pharmaceutical and nutraceutical selection and packaging

Info

Publication number: WO2007075378A2
Application number: PCT/US2006/047835
Authority: WO
Inventors: Edward K. Y. Jung; Royce A. Levien; Robert W. Lord; Mark A. Malamud; John D. Rinaldo, Jr.; Lowell L. Wood, Jr.
Original assignee: Searete Llc
Priority date: 2005-12-20
Filing date: 2006-12-13
Publication date: 2007-07-05
Also published as: WO2007075378A3; EP1964040A2

Abstract

The present disclosure relates to computational and/or control systems related to individualized pharmaceutical and nutraceutical selection and packaging.

Description

COMPUTATIONAL AND/OR CONTROL SYSTEMS

RELATED TO INDIVIDUALIZED PHARMACEUTICAL AND

NUTRACEUTICAL SELECTION AND PACKAGING

CROSS-REFERENCE TO RELATED APPLICATIONS

The present application is related to and claims the benefit of the earliest available effective filing date(s) from the following listed application(s) (the "Related Applications") (e.g., claims earliest available priority dates for other than provisional patent applications or claims benefits under 35 USC § 119(e) for provisional patent applications, for any and all parent, grandparent, great-grandparent, etc. applications of the Related Apρlication(s)).

RELATED APPLICATIONS:

For purposes of the USPTO extra-statutory requirements, the present application constitutes a continuation-in-part of United States Patent Application No. 11/453,57I₃ entitled INDIVIDUALIZED PHARMACEUTICAL SELECTION AND PACKAGING, naming Edward K. Y. Jung, Royce A. Levien, Robert W. Lord, Mark A. Malamud, John D. Rinaldo, Jr., and Lowell L. Wood, Jr. as inventors, filed 14 June 2006.

For purposes of the USPTO extra-statutory requirements, the present application constitutes a continuation-in-part of United States Patent Application No. 11/478,341, entitled COMPUTATIONAL AND/OR CONTROL SYSTEMS RELATED TO INDIVIDUALIZED NUTRACEUTICAL SELECTION AND PACKAGING, naming Edward K. Y. Jung, Royce A. Levien, Robert W. Lord, Mark A. Malamud, John D. Rinaldo, Jr., and Lowell L. Wood Jr. as inventors, filed 28 June 2006.

For purposes of the USPTO extra-statutory requirements, the present application constitutes a continuation-in-part of United States Patent Application No. 11/478,296, entitled COMPUTATIONAL AND/OR CONTROL SYSTEMS RELATED TO INDIVIDUALIZED NUTRACEUTICAL SELECTION AND PACKAGING, naming Edward K.Y. Jung, Royce A. Levien, Robert W. Lord, Mark A. Malamud, John D. Rinaldo, Jr., and Lowell L. Wood Jr. as inventors, filed 28 June 2006.

For purposes of the USPTO extra-statutory requirements, the present application is related to United States Patent Application No. Not Yet Assigned, Attorney Docket Number 1105-022-032A, entitled COMPUTATIONAL AND/OR CONTROL SYSTEMS RELATED TO INDIVIDUALIZED PHARMACEUTICAL AND NUTRACEUTICAL SELECTION AND PACKAGING, naming Edward K. Y. Jung, Royce A. Levien, Robert W. Lord, Mark A. Malamud, John D. Rinaldo., Jr., and Lowell L. Wood Jr. as inventors, filed 14 July 2006, herein incorporated by reference to the extent such, subject matter is not inconsistent herewith.

For purposes of the USPTO extra-statutory requirements, the present application is related to United States Patent Application No. 11/474,109, entitled CUSTOMIZED VISUAL MARKING FOR MEDICATION LABELING₅ naming Edward K. Y. Jung, Royce A. Levien, Robert W. Lord, Mark A. Malamud, John D. Rinaldo, Jr., and Lowell L. Wood Jr. as inventors, filed 23 June 2006, herein incorporated by reference to the extent such subject matter is not inconsistent herewith.

For purposes of the USPTO extra-statutory requirements, the present application is related to United States Patent Application No. 11/314,945, entitled GENERATING A REQUEST FROM A NUTRACEUTICAL INVENTORY₅ naming Edward K. Y. Jung, Royce A. Levien, Robert W. Lord, Mark A. Malamud, John D. Rinaldo, -Jr., Clarence T. Tegreene, and Lowell L. Wood Jr. as inventors, filed 20 December 2005, herein incorporated by reference to the extent such subject matter is not inconsistent herewith.

For purposes of the USPTO extra-statutory requirements, the present application is related to United States Patent Application No. 11/291,482, entitled GENERATING A NUTRACEUTICAL REQUEST FROM AN INVENTORY, naming Edward K. Y. Jung, Royce A. Levien, Robert W. Lord, Mark A. Malamud, John D. Rinaldo, Jr., Clarence T. Tegreene, and Lowell L. Wood Jr. as inventors, filed 30 November 2005, herein incorporated by reference to the extent such subject matter is not inconsistent herewith.

The United States Patent Office (USPTO) has published a notice to the effect that the USPTO's computer programs require that patent applicants reference both a serial number and indicate whether an application is a continuation or continuation-in-part. Stephen G. Kunin, Benefit of Prior-Filed Application, USPTO Official Gazette March 18, 2003, available at http://www.uspto.gov/web/offices/com/sol/og/2003/weekl l/ patbene.htm. The present applicant entity has provided above a specific reference to the application^) j^-øm which priority is being claimed as recited by statute. Applicant entity understands that the statute is -unambiguous in its specific reference language and does not require either a serial number or any characterization, such as "continuation" or "continuation-in-part," for claiming priority to U.S. patent applications. Notwithstanding the foregoing, applicant entity understands that the USPTO 's computer programs have certain data entry requirements, and hence applicant entity is designating the present application as a continuation-in-part of its parent applications as set forth above, but expressly points out that such designations are not to be construed in any way as any type of commentary and/or admission as to whether or not the present application contains any new matter in addition to the matter of its parent applications) .

All subject matter of the Related Applications and of any and all parent, grandparent, great-grandparent, etc. applications of the Related Applications is incorporated herein by reference to the extent such subject matter is not inconsistent herewith.

TECHNICAL FIELD

The present disclosure relates to computational and/or control systems related to individualized selection and packaging of pharmaceutical agents and nutraceutical agents.

SUMMARY

In some embodiments a method is provided that includes accepting input of one or more parameters specifically associated with an individual, selecting one or more pharmaceutical agents in response to at least one of the one or more parameters specifically associated with the individual, selecting one or more nutraceutical agents in response to at least one of the one or more parameters specifically associated with the individual, and packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents in administration form in response to at least one of the one or more parameters specifically associated with the individual. In addition to the foregoing, other method aspects are described in the claims, drawings, and/or text forming a part of the present disclosure.

In some embodiments a system is provided that includes circuitry for accepting input of one or more parameters specifically associated with an individual, circuitry for selecting one or more pharmaceutical agents in response to at least one of the one or more parameters specifically associated with the individual, circuitry for selecting one or more nutraceutical agents in response to at least one of the one or more parameters specifically associated with the individual. In addition to the foregoing, other system aspects are described in the claims, drawings, and/or text forming a part of the present disclosure.

In some embodiments a system is provided that includes means for accepting input of one or more parameters specifically associated with an individual, means for selecting one or more pharmaceutical agents in response to at least one of the one or more parameters specifically associated with the individual, means for selecting one or more nutraceutical agents in response to at least one of the one or more parameters specifically associated with the individual, and means for packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents in administration form in response to at least one of the one or more parameters specifically associated with the individual. In some embodiments, such means include but are not limited to circuitry and/or programming for effecting the herein-referenced functional aspects; the circuitry and/or programming can be virtually any combination of hardware, software, and/or firmware configured to effect the herein-referenced functional aspects depending upon the design choices of the system designer. In addition to the foregoing, other system aspects means are described in the claims, drawings, and/or text forming a part of the present disclosure.

In some embodiments a system is provided that includes a signal-bearing medium bearing at least one of: one or more instructions for accepting input of one or more parameters specifically associated with an individual; one or more instructions for selecting one or more pharmaceutical agents in response to at least one of the one or more parameters specifically associated with the individual; one or more instructions for selecting one or more nutraceutical agents in response to at least one of the one or more parameters specifically associated with the individual; and one or more instructions for packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents in administration foπii in response to at least one of the one or more parameters specifically associated with the individual. In addition to the foregoing, other system aspects are described in the claims, drawings, and/or text forming a part of the present disclosure.

In some embodiments a method is provided that includes accepting input of one or more parameters associated with an individual, selecting one or more pharmaceutical agents in response to at least one of the one or more parameters associated with the individual, selecting one or more nutraceutical agents in response to at least one of the one or more parameters associated with the individual, and packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents in administration form in response to at least one of the one or more parameters associated with the individual. In addition to the foregoing, other method aspects are described in the claims, drawings, and/or text forming a part of the present disclosure. In some embodiments a system is provided that includes circuitry for accepting input of one or more parameters associated with an individual, circuitry for selecting one or more pharmaceutical agents in response to at least one of the one or more parameters associated with the individual, circuitry for selecting one or more nutraceutical agents in response to at least one of the one or more parameters associated with the individual, and circuitry for packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents in administration form in response to at least one of the one or more parameters associated with the individual. In addition to the foregoing, other system aspects are described in the claims, drawings, and/or text forming a part of the present disclosure.

In some embodiments a system is provided that includes means for accepting input of one or more parameters associated with an individual, means for selecting one or more pharmaceutical agents in response to at least one of the one or more parameters associated with the individual, means for selecting one or more nutraceutical agents in response to at least one of the one or more parameters associated with the individual, and means for packaging at least one of the one or more pharmaceutical agents and at least one of the one or more' nutraceutical agents in administration form in response to at least one of the one or more parameters associated with the individual. In some embodiments, such means include but are not limited to circuitry and/or programming for effecting the herein-referenced functional aspects; the circuitry and/or programming can be virtually any combination of hardware, software, and/or firmware configured to effect the herein-referenced functional aspects depending upon the design choices of the system designer. In addition to the foregoing, other system aspects means are described in the claims, drawings, and/or text forming a part of the present disclosure. In some embodiments a system is provided that includes a signal -bearing medium bearing at least one of: one or more instructions for accepting input of one or more pai-ameters associated with an individual, one or more instructions for selecting one or more pharmaceutical agents in response to at least one of the one or more parameters associated with the individual, one or more instructions for selecting one or more nutraceutical agents in response to at least one of the one or more parameters associated with the individual, and one or more instructions for packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents in administration form in response to at least one of the one or more parameters associated with the individual. In addition to the foregoing, other system aspects are described in the claims, drawings, and/or text forming a part of the present disclosure.

In some embodiments, related systems include but are not limited to circuitry and/or programming for effecting the herein-referenced method aspects; the circuitry and/or programming can be virtually any combination of hardware, software, and/or firmware configured to effect the herein-referenced method aspects depending upon the design choices of the system designer. In addition to the foregoing, other system aspects are described in the claims, drawings, and/or text forming a part of the present application.

The foregoing summary is illustrative only and is not intended to be in any way limiting. In addition to the illustrative aspects, embodiments, and features described above, further aspects, embodiments, and features will become apparent by reference to the drawings, claims, and the following detailed description.

BRIEF DESCRIPTION OF THE FIGURES

FIG. 1 illustrates an example system 100 in which embodiments may be implemented.

FIG. 2 illustrates an operational flow representing example operations related to methods for individualized pharmaceutical selection and packaging.

FIG. 3 illustrates alternative embodiments of the example operation flow of FIG. 2. FIG. 4 illustrates alternative embodiments of the example operation flow of FIG.

2.

FIG. 5 illustrates alternative embodiments of the example operation flow of FIG.

2.

FIG. 6 illustrates alternative embodiments of the example operation flow of FIG.

2.

FIG. 7 illustrates alternative embodiments of the example operation flow of FIG.

2.

FIG. 8 illustrates alternative embodiments of the example operation flow of FIG.

2.

FIG. 9 illustrates alternative embodiments of the example operation flow of FIG.

2.

FIG. IO illustrates alternative embodiments of the example operation flow of FIG.

2.

FIG. 11 illustrates alternative embodiments of the example operation flow of FIG.

2.

FIG. 12 illustrates alternative embodiments of the example operation flow of FIG.

2.

FIG. 13 illustrates alternative embodiments of the example operation flow of FIG.

2.

FIG. 14 illustrates alternative embodiments of the example operation flow of FIG.

2.

FIG. 15 illustrates alternative embodiments of the example operation flow of FIG.

2.

FIG. 16 illustrates alternative embodiments of the example operation flow of FIG.

2.

FIG. 17 illustrates alternative embodiments of the example operation flow of FIG.

2.

FIG. 18 illustrates alternative embodiments of the example operation flow of FIG.

2. FIG. 19 illustrates alternative embodiments of the example operation flow of FIG. 2.

FIG. 20 illustrates alternative embodiments of the example operation flow of FIG. 2.

FIG. 21 illustrates alternative embodiments of the example operation flow of FIG. 2.

FIG. 22 illustrates alternative embodiments of the example operation flow of FIG. 2.

FIG. 23 illustrates alternative embodiments of the example operation flow of FIG. 2.

FIG. 24 illustrates an example system 2400 in which embodiments may be implemented.

FIG. 25 illustrates an example system 2500 in which embodiments may be implemented.

DETAILED DESCRIPTION

In the following detailed descziption, reference is made to the accompanying drawings, which form a part hereof. In the drawings, similar symbols typically identify similar components, unless context dictates otherwise. The illustrative embodiments described in the detailed description, drawings, and claims are not meant to be limiting. Other embodiments may be utilized, and other changes may be made, without departing from the spirit or scope of the subject matter presented here.

While various aspects and embodiments have been disclosed herein, other aspects and embodiments will be apparent to those skilled in the art. The various aspects and embodiments disclosed herein are for purposes of illustration and are not intended to be limiting, with the true scope and spirit being indicated by the following claims.

Fig. 1 illustrates an example system 100 in which embodiments may be implemented. In some embodiments, the system 100 is operable to provide a method and system for individualized pharmaceutical and nutraceutical selection and packaging. In some embodiments, one or more accepting units 102 accept input 104 of one or more parameters 106 associated with an individual 108, one or more selecting units 110 may then select one or more pharmaceutical agents 1 12 and one or more nutraceutical agents 122 in response to at least one of the one or more parameters 106 associated with the individual 108, and one or more packaging units 1 14 may then package the one or more pharmaceutical agents 1 12 and the one or more nutraceutical agents 122 in response to at least one of the one or more parameters 106 associated with the individual 108. In some embodiments, the one or more pharmaceutical agents 112 and the one or more nutraceutical agents 122 may be packaged and output 116 in an administration form that may be administered to an individual 108. In some embodiments, the system provides for user interaction 1 18 with a user 120. In some embodiments, one or more users 120 may provide input 104 to one or more accepting units 102. In some embodiments, one or more users 120 may interact with one or more accepting units 102. In some embodiments, one or more users 120 may interact with one or more selecting units 110. In some embodiments, one or more users 120 may interact with one or more packaging units 114. In some embodiments, one or more users 120 may interact with one or more accepting units 102, one or more selecting units 110, one or more packaging units 114, and/or substantially any combination thereof. In some embodiments, the individual units may be combined together into a single system 100. For example, in some embodiments, the accepting unit 102, selecting unit 110, and packaging unit 114 may all be combined into a single system 100. In some embodiments, the individual units maybe located in separate locations. For example, an accepting unit 102 may be located in one area, a selecting unit 1 10 may be located in another area, and a packaging unit 114 may be located in yet another area. For example, in some embodiments, an accepting unit 102 may be in the form of a personal digital assistant into which an individual 108 can input 104 parameters 106 associated with the individual 108. One or more separately located selecting units 1 10 may receive information from one or more accepting units 102 and select one or more pharmaceutical agents 112 and/or one or more nutraceutical agents 122 in response to the one or more parameters 106 associated with the individual 108. A separately located packaging unit 114 may receive information from the one or more selecting units 1 10 and package one or more pharmaceutical agents 112 and one or more nutraceutical agents 122 in response to the one or more parameters 106 associated with the individual 108. Accordingly, the individual units of the system 100 described in Figure I may be oriented in substantially any physical combination. Such systems 100 may be located in numerous areas. Examples of such areas include, but are not limited to, hospitals, clinics, physician's offices, dentist's offices, pharmacies, homes, nutraceutical companies, pharmaceutical companies, veterinary clinics, stores (i.e., health-food stores, food supplement stores, sporting goods stores, grocery stores, and the like), pet-owners homes, gyms, and the like.

FIG. 2 illustrates an operational flow 200 representing examples of operations that are related to the performance of a method for individualized pharmaceutical and nutraceutical selection and packaging. In FIG. 2 and in following figures that include various examples of operations used during performance of the method, discussion and explanation may be provided with respect to the above-described example of FIG. 1, and/or with respect to other examples and contexts. However, it should be understood that the operations may be executed in a number of other environments and contexts, and/or modified versions of FIG. 1. Also, although the various operations are presented in the sequence(s) illustrated, it should be understood that the various operations may be performed in other orders than those which are illustrated, or may be performed concurrently.

After a start operation, the operational flow 200 includes an accepting operation 210 involving accepting input of one or more parameters specifically associated with an individual. In some embodiments, one or more accepting units 102 may accept input 104 of one or more parameters 106 associated with an individual 108.

In some embodiments, an individual 108 may be a human. In some embodiments, an individual 108 may be a non-human animal. Examples of such non-human animals include, but are not limited to, domestic pets such as dogs, cats, horses, potbelly pigs, ferrets, rodents, reptiles, amphibians, and the like. Non-human animals also include animals that include, but are not limited to, ca.tt.le, sheep, goats, chickens, pigs, and the like. Accordingly, the systems and methods described herein may be used in association with substantially any human and/or non-human animal.

Numerous parameters 106 may be associated with an individual 108. Such parameters 106 may include, but are not limited to, physical characteristics, metabolic characteristics, financial characteristics, and the like. Examples of parameters 106 include, an individual's height, weight, gender, kidney function, liver function, level of physical fitness, age, allergic response, metabolic level (i.e., resting metabolic rate and/or activity-related metabolic rate), disease state, body fat percentage, personal health habits (i.e., smoking, alcohol consumption, diet, illegal drug use, and the like), family health history, insurance coverage, food supplement usage, nurraceutical usage, non-prescription drug use, prescription drug use, pregnancy status, and the like. In some embodiments, the one or more parameters 106 may be specifically associated with an individual 108. As such, in some embodiments, the one or more parameters 106 may be unique to the individual 108 as opposed to being common to a group. For example, in some embodiments, an individual 108 may be a member of a group of persons who are diabetic while exhibiting one or more parameters 106, such as metabolic characteristics, that are unique to the individual 108. Accordingly, in some embodiments, one or more parameters 106 may be input that provide for selection of pharmaceutical agents 112 and for selection of nutraceutical agents 122 in accordance with one or more parameters 106 that are specifically associated with an individual 108. In some embodiments, one or more parameters 106 are not specifically associated with an individual 108.

Numerous technologies may be used to provide input 104 that include one or more parameters 106 associated with an individual 108. Examples of such technologies include, but are not limited to, hardwired input 104, wireless input 104, computer input 104, telephonic input 104, internet based input 104, intranet based input 104, digital input 104, analog input 104, input 104 from a human, input 104 from a palm held organizer, input 104 from a personal digital assistant, input 104 from a web enabled cellular telephone, and the like. In some embodiments, one or more accepting units 102 accept input 104 from one source. In some embodiments, one or more accepting units 102 accept input 104 from more than one source. For example, in some embodiments, an accepting unit 102 may accept input 104 from an insurance company, a physician, a pharmacist, a clinical laboratory, a pharmaceutical company, and a nutraceutical company. In some embodiments, input 104 may be associated with a physician input 104, a pharmacist input 104, a patient input 104, a machine input 104 and/or substantially any combination thereof. In some embodiments, an accepting unit 102 may include an input device. For example, in some embodiments, an accepting unit 102 may include an interface, such as a keyboard, touch-screen and/or the like, where parameters 106 associated with an individual 108 may be input 104 directly into the accepting unit 102. In some embodiments, an accepting unit 102 may lack an interface where parameters 106 associated with an individual 108 may be directly input 104 into the accepting unit 102. In some embodiments, an accepting unit 102 may accept input 104 of one or more parameters 106 associated with an individual 108 from one or more locations that are remote from the accepting unit 102. For example, in some embodiments, an accepting unit 102 may accept input 104 from a wireless device, the internet, an intranet, a telephone, a palm held organizer, input 104 from a personal digital assistant, input 104 from a web enabled cellular telephone, and the like.

After a start operation, the operational flow 200 includes a selecting operation 220 involving selecting one or more pharmaceutical agents in response to at least one of the one or more parameters specifically associated with the individual. In some embodiments, one or more selecting units 110 may select one or more pharmaceutical agents 112 in response to at least one of the one or more parameters 106 associated with the individual 108.

In some embodiments, one or more selecting units 110 act to select one or more pharmaceutical agents 112 in response to at least one of the one or more parameters 106 associated with an individual 108. In some embodiments, one or more selecting units 110 may select one or more first pharmaceutical agents 112 in response to at least one of the one or more parameters 106 associated with an individual 108 and select one or more second pharmaceutical agents 112 based on the identity of the one or more first pharmaceutical agents 112 selected. For example, in some embodiments, one or more selecting units 110 may select the first and second pharmaceutical agents 112 to act synergistically with each other when administered to an individual 108. In some embodiments, one or more selecting units 110 may select the first and second pharmaceutical agents 1 12 so that they do not contraindicate each other when administered to an individual 108. In some embodiments, one or more selecting units 1 10 may select one or more pharmaceutical agents 112 in response to at least one of the one or more parameters 106 associated with an individual 108 and select one or more nutraceutical agents 122 based on the identity of the one or more pharmaceutical agents 112 selected. For example, in some embodiments, one or more selecting units 1 10 may select one or more pharmaceutical agents 1 12 that act synergistically with one or more nutraceutical agents 122 when administered to an individual 108. For example, selective serotonin reuptake inhibitors (SSRI) may cause sexual dysfunction and decreased sex drive. Giπlco Biloba was found to relieve many of these adverse side effects when coadministered with selective serotonin reuptake inhibitors (SSRI). In some embodiments, one or more selecting units 110 may select one or more pharmaceutical agents 1 12 that do not contraindicate one or more nutraceutical agents 122 when administered to an individual 108. For example, administration of St. John's Wort and/or 5-hydroxytryptophan in combination with pharmaceutical agents 112 that are selective serotonin reuptake inhibitors (SSRI) may cause hallucinations, fluctuating blood pressure, seizure, high temperatures, and irregular heart beat. Pharmaceutical agents 112 may be selected in response to numerous parameters 106. Numerous pharmaceutical agents 112 are known (i.e., The Merck Index, 13^th Edition, An Encyclopedia of Chemicals, Drugs, and Biologicals, Merck & Co. Inc., Whitehouse Station, NJ 2001; Mosby's Drug Guide, Mosby, Inc., St. Louis, MO 2004; Remington: The Science and Practice of Pharmacy, 20^th Edition, Lippincott Williams & Wilkins, Philadelphia, PA 2000; Physicians' Desk Reference, 58^lh Edition, Thompson, PDR, Montvale, NJ 2004; U.S. Patent No. 6,773,721, herein incorporated by reference). In some embodiments, one or more pharmaceutical agents 112 may be available by prescription. In some embodiments, one or more pharmaceutical agents 112 may be available without a prescription. In some embodiments, one or more pharmaceutical agents 112 may be selected in response to at least one parameter 106 that is not specific to an individual 108. After a start operation, the operational flow 200 includes a selecting operation 230 involving selecting one or more nutraceutical agents in response to at least one of the one or more parameters specifically associated with the individual. In some embodiments, one or more selecting units 110 may select one or more nutraceutical agents 122 in response to at least one of the one or more parameters 106 specifically associated with the individual 108. In some embodiments, one or more selecting units 110 act to select one or more nutraceutical agents 122 in response to at least one of the one or more parameters 106 associated with an individual 108. In some embodiments, one or more selecting units 1 10 may select one or more first nutraceutical agents 122 in response to at least one of the one or more parameters 106 associated with an individual 108 and select one or more second nutraceutical agents 122 based on the identity of the one or more first nutraceutical agents 122 selected. For example, in some embodiments, one or more selecting units 1 10 may select the first and second nutraceutical agents 122 to act synergistically with each other when administered to an individual 108. In some embodiments, one or more selecting units 110 may select the first and second nutraceutical agents 122 so that they do not contraindicate each other when administered to an individual 108. In some embodiments, one or more selecting units 110 may select one or more nutraceutical agents 122 in response to at least one of the one or more parameters 106 associated with an individual 108 and select one or more pharmaceutical agents 112 based on the identity of the one or more nutraceutical agents 122 selected. For example, in some embodiments, one or more selecting units 110 may select one or more nutraceutical agents 122 that act synergistically with one or more pharmaceutical agents 1 12 when administered to an individual 108. In some embodiments, one or more selecting units 110 may select one or more nutraceutical agents 122 that do not contraindicate one or more pharmaceutical agents 112 when administered to an individual 108. Nutraceutical agents 122 may be selected in response to numerous parameters 106. In some embodiments, one or more nutraceutical agents 122 may be selected in response to at least one parameter 106 that is not specific to an individual 108. Nutraceutical agents 122 typically include natural, bioactive chemical compounds or any substance that is a plant, food, an extracted part of a food, that provides medical or health benefits but which generally fall outside regulations controlling pharmaceuticals. Included in this category of substances may be foods, isolated nutrients, supplements and herbs. Nutraceuticals are often referred to as phytochemicals or functional foods and include dietary supplements. Numerous nutraceuticals have been described (i.e., Roberts et aL, Nutraceuticals: The Complete Encyclopedia of Supplements, Herbs, Vitamins, and Healing Foods, l^sl Edition, Perigee Trade (2001) and Susan G. Wynn, Emerging Therapies: Using Herbs and Nutraceuticals for Small Animals, American Animal Hospital Assn Press (1999)). Examples of nutraceutical agents 122 include, but are not limited to, Amino Acids, Terpenoids, Carotenoid Terpenoids (Lycopene, Beta-Carotene, Alpha-Carotene, Lutein, Zeaxanthin, Astaxanthin), Non-Carotenoid Terpeniods (Perillyl Alcohol, Saponins, Terpeneol, Terpene Limonoids), Polyphenolics, Flavonoid Polyphenolics (Anthocyanins, Catechins, Isoflavones, Hesperetin, Naringin, Rutin, Quercetin, Silymarin, Tangeretin, Tannins), Phenolic Acids (Ellagic Acid, Chlorogenic Acid, Para-Coumaric Acid, Phytic Acid, Cinnamic Acid), Other Non-Flavonoid Polyphenolics (Curcumin, Resveratrol, Lignans), Glucosinolates, Isothiocyanates (Phenethyl Isothiocyanate, Benzyl Isothiocyanate, Sulforaphane), Indoles (Indole-3- Carbinol (I3C), Thiosulfonates, Phytosterols (Beta-Sitosterol), Anthraquinones (Senna, Barbaloin, Hypericin), Capsaicin, Piperine, Chlorophyll, Betaine, Pectin, Oxalic Acid, Acetyl-L-Carnitine, Allantoin, Androsterondiol, Androsterondione, Betaine (Trimethylglycine), Caffeine, Calcium pyvurate (Pyruvic Acid), Carnitine, Caraosine, Carotene (alpha & beta), Carotenoid (Total for beadlets), Choline, Chlorogenic Acid, Cholic Acid (Ox Bile), Chondroitin Sulfate, Chondroitin Sulfate (Total Mucopolysaccharides), Cholestin, Chrysin, Coenzyme QlO (Co-QlO), Conjugated Linoleic Acid (CLA), Corosolic Acid, Creatine, Dehydroepiaπdrosterone (DHEA), Dichlorophen, Diindolymethane (DIM), Dimethyglycine (DMG)₅ Dimercapto Succinic Acid (DMSA), Ebselen, Ellagic Acid, Fisetin, Forrnonetin, Glucaric Acid (Glucarate), Glucosamine (HCl or Sulfate), Glucosamine (N-Acetyl), Glutathione (Reduced), Hesperidine, Hydroxy-3-Methylbutyric Acid (HMB), 5-Hydroxytryptophan (L-5-HTP), Indole-3-CarbinoI, Inositol, Isothiocyanates, Linolenic Acid-Gamma (GLA), Lipoic Acid (alpha), Lutein, Lycopene, Melatonin, Methylsulfonylmethane (MSM), Naringin, Pancreatin, Para-aminobenzoic Acid (PABA), Paraben (methyl or propyl), Phenolics, Phosphatidylcholine (Lecithin), Phosphatidylserine, Phospholipids, Phytosterols, Pregersterone, Pregnenolone, Quercetin, Resveratrol, D-Ribose, Rutin, S- adenosylmethionine (SAM-e), Salicylic Acid, Sulforaphane, Tartaric Acid, Taxifolin, Tetrahydropalmatine, Thephyline, Theobromine, Tigogenin, Troxerutin, Tryptophan, Tocotrieπol (alph, beta Sc gamma), Zeaxanthin, Gingo Biloba, Ginger, Cat'a Claw, Hypericum, Aloe Vera, Evening Primrose, Garlic, Capsicum, Dong Quai, Ginseng, Feverview, Fenugreek, Echinacea, Green Tea, Marshmallow, Saw Palmetto, Tea Tree Oil, Payllium, Kava-Kava, Licorice Root, Manonia Aquifolium, Hawthorne, Hohimbr, Tumeric, Witch Hazel, Valerian, Mistletoe, Bilberry, Bee Pollen, Peppermint Oil, Beta- Carotene, Genistein, Lutein, Lycopene, the Polyphenols (bioflavonoids), and the like.

In some embodiments, nutraceutical agents 122 may include microbes (i.e., probiotics). Examples of such microbes include, but are not limited to, Lactobacillus acidophilus, Lactobacillus plantarum, Lactobacillus casei, Bifidobacterium bifidum, Bifidobacterium Iongum, Saccharomyces boulardii, Saccharomyces cerevisiae, and the like (i.e., Samuel and Gordon, A humanized gnotobiotic mouse model of host-archaeal- bacterial mutualism, PNAS, 103:26 (pg. 10011-10016 (2006)). In some embodiments, nutraceutical agents 122 may include non-living microbes. For example, non-living Saccharomyces cerevisiae may be used as a source of vitamin B 12. In some embodiments, recombinant microbes may be utilized as nutraceutical agents 122. For example, in some embodiments, microbes may be genetically modified to produce, or overexpress, one or more nutraceutical agents 122.

After a start operation, the operational flow 200 includes a packaging operation 240 involving packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents in administration form in response to at least one of the one or more parameters specifically associated with the individual. In some embodiments, one or more packaging units 114 may package at least one of the one or more pharmaceutical agents 112 and at least one of the one or more nutraceutical agents 122 in administration form in response to at least one of the one or more parameters 106 specifically associated with the individual 108.

Numerous types of packaging units 114 may be used to package the one or more pharmaceutical agents 112 and the one or more nutraceutical agents 122. In some embodiments, one packaging unit 1 14 may be used to package one or more pharmaceutical agents 1 12 and one or more nutraceutical agents 122. In some embodiments, one or more packaging units 1 14 may be used to package one or more pharmaceutical agents 112 and one or more nutraceutical agents 122. In some embodiments, two or more packaging units 1 14 may be used to package one or more pharmaceutical agents 112 and one or more nutraceutical agents 122. In some embodiments, a first packaging unit 1 14 may package one or more first pharmaceutical agents 1 12 and/or one or more first nutraceutical agents 122, a second packaging unit 114 may package one or more second pharmaceutical agents 1 12 and/or one or more second nutraceutical agents 122, and a third packaging unit 1 14 may package one or more third pharmaceutical agents 112 and/or one or more third nutraceutical agents 122 together. In some embodiments, one packaging unit 1 14 may package the one or more nutraceutical agents 122. In some embodiments, one or more packaging units 114 may formulate one or more pharmaceutical agents 1 12 and one or more nutraceutical agents 122 for administration to an individual 108. In some embodiments, one or more packaging units 1 14 may package one or more preformulated pharmaceutical agents 112 and one or more preformulated nutraceutical agents 122 for administration to an individual 108. For example, in some embodiments, one or more packaging units 114 may package one or more commercially available pharmaceutical preparations and one or more commercially available nutraceutical preparations to provide for single administration to an individual 108. In some embodiments, one or more packaging units 114 may package one or more preformulated tablets containing one or more pharmaceutical agents 112 and one or more nutraceutical agents 122 into a single capsule for administration to an individual 108. In some embodiments, one or more packaging units 1 14 may wrap one or more second pharmaceutical agents 112 and/or one or more second nutraceutical agent 122 around one or more first pharmaceutical agents 112 and/or one or more first nutraceutical agents 122 through use of a biocompatible and dissolvable wrapper to produce an administration form having the first and second pharmaceutical agents 112 and/or first and second nutraceutical agents 122 in concentric orientation relative to each other. In some embodiments, one or more packaging units 114 may package one or more pharmaceutical agents 112 and one or more nutraceutical agents 122 into a compartmentalized capsule. In some embodiments, one or more packaging units 114 may package one or more pharmaceutical agents 1 12 and one or more nutraceutical agents 122 into a single administration form for administration to an individual 108. In some embodiments, one or more packaging units 1 14 may package at least one of the one or more pharmaceutical agents 112 and at least one of the one or more nutraceutical agents 122 in administration form in response to at least one of the one or more parameters 106 that are not specifically associated with an individual 108.

FJG. 3 illustrates alternative embodiments of the example operational flow 200 of FIG. 2. FIG. 3 illustrates example embodiments where the accepting operation 210 may include at least one additional operation. Additional operations may include an operation 302, operation 304, operation 306, operation 308, and/or operation 310.

At operation 302, the accepting operation 210 may include accepting the one or more parameters specifically associated with a human individual. In some embodiments, one or more accepting units 102 may accept the one or more parameters 106 specifically associated with a human individual 108.

In some embodiments, the one or more parameters 106 may include physical characteristics, metabolic characteristics, financial characteristics, and substantially any combination thereof. In some embodiments, such parameters 106 may include, alone or in combination and not limited to, an individual's height, weight, gender, kidney function, liver function, level of physical fitness, age, allergic response, metabolic level (i.e., resting metabolic rate and/or activity-related metabolic rate), disease state, body fat percentage, personal habits (i.e., smoking, alcohol consumption, diet, illegal drug use, and the like), family health history, insurance coverage, food supplement usage, physical activities, sleep schedule, activity level, occupation, nutraceutical usage, non-prescription drug use, prescription drug use, pregnancy status, predisposition toward the development of a malady, genotype, phenotype, genetic predisposition, administration form of a nutraceutical agent 122, administration form of a pharmaceutical agent 112, mode of administration, time of administration, administration schedule, exposure to pathogens, potential exposure to pathogens, exposure to toxins, potential exposure to toxins, and the like. For example, in some embodiments, one or more parameters 106 associated with a human child may be input 104. Accordingly, such parameters 106 may provide for selection of one or more pharmaceutical agents 1 12 and/or one or more nutraceutical agents 122 that may be administered to a human child. In other embodiments, such parameters 106 may provide for selection against one or more pharmaceutical agents 112 and/or one or more nutraceutical agents 122 that should not be administered to a human child. Accordingly, in some embodiments, an input 104 may provide for the selection of one or more pharmaceutical agents 1 12 and/or one or more nutraceutical agents 122. However, in other embodiments, an input 104 may provide for selection against one or more pharmaceutical agents 1 12 and/or one or more nutraceutical agents 122. In some embodiments, parameters 106 may be input 304 that relate to environmental factors such as, time, temperature, elevation, humidity, events, activities and the like. For example, an input 104 may include parameters 106 related to an individual 108 who is a mountain climber. Accordingly, one or more pharmaceutical agents 112 and/or one or more nutraceutical agents 122 may be selected that will not vaporize under lessened atmospheric pressure, that will not freeze, and/or that will not break. In some embodiments, one or more parameters 106 may be input 104 that relate to administration form and mode of administration of the one or more pharmaceutical agents 112 and/or one or more nutraceutical agents 122 to the individual 108. For example, in some embodiments, one or more parameters 106 may be input 104 that indicate that the individual 108 prefers to orally ingest pharmaceutical agents 112 and/or nutraceutical agents 122. In some embodiments, one or more parameters 106 may be input 104 that indicate that the individual 108 is to ingest one or more pharmaceutical agents 112 and/or one or more nutraceutical agents 122 within a given time period. Accordingly, in some embodiments, an input 104 may be associated with the selection of one or more pharmaceutical agents 1 12 and/or one or more nutraceutical agents 122 that are compatible with each other and/or that do not contraindicate each other. In some embodiments, an input 104 may be associated with the selection of one or more pharmaceutical agents 112 and/or one or more nutra.ceutical agents 122 that act in a synergistic manner when administered to an individual 108.

At operation 304, the accepting operation 210 may include accepting the one or more parameters specifically associated with a non-human individual. In some embodiments, one or more accepting units 102 may accept the one or more parameters 106 specifically associated with a non-human individual 108.

Examples of such non-human animals include, but are not limited to, domestic pets such as dogs, cats, horses, potbelly pigs, ferrets, rodents, reptiles, amphibians, and the like. Non-human animals may also be animals that include, but are not limited to, cattle, sheep, goats, chickens, pigs, and the like. Accordingly, in some embodiments, the methods and/or systems described herein may be used for veterinary purposes. In some embodiments, the one or more parameters 106 may include physical characteristics, metabolic characteristics, financial characteristics (such as valuation of the non-human animal), and substantially any combination thereof. In some embodiments, such parameters 106 may include, alone or in combination and not limited to, a non-human individual's height, weight, gender, kidney function, liver function, level of physical fitness, age, allergic response, metabolic level (i.e., resting metabolic rate and/or activity- related metabolic rate), disease state, body fat percentage, health history, insurance coverage, food supplement usage, physical activities, sleep schedule, activity level, nutraceutical usage, non-prescription drug use, prescription drug use, pregnancy status, predisposition toward the development of a malady, genotype, phenotype, genetic predisposition, administration form, mode of administration, exposure to pathogens, potential exposure to pathogens, exposure to toxins, potential exposure to toxins, and the like. For example, in some embodiments, parameters 106 associated with an infant non- human individual 108 may be input 104. Accordingly, such parameters 106 may provide for selection of one or more pharmaceutical agents 112 and/or one or more nutraceutical agents 122 that may be administered to an infant non-human individual 108. In other embodiments, such parameters 106 may provide for selection against one or more pharmaceutical agents 112 and/or one or more nutraceutical agents 122 that should not be administered to an infant non-human individual 108. Accordingly, in some embodiments, an input 104 may provide for the selection of one or more pharmaceutical agents 112 and/or one or more nutraceutical agents 122. However, in other embodiments, an input 104 may provide for selection against one or more pharmaceutical agents 1 12 and/or one or more nutraceutical agents 122. In some embodiments, parameters 106 may be input 104 that relate to environmental factors surrounding the non-human individual 108 that include time, temperature, elevation, humidity, events, activities and the like. In some embodiments, one or more parameters 106 may be input 104 that relate to administration form and mode of administration of the one or more pharmaceutical agents 1 12 and/or one or more nutraceutical agents 122 to the non-human individual 108. For example, in some embodiments, one or more parameters 106 may be input 104 that indicate that one or more pharmaceutical agents 1 12 and/or one or more πutraceutical agents 122 should be administered to the non-human individual 108 orally. In some embodiments, one or more parameters 106 may be¹ input 104 that indicate that the non-human individual 108 is to ingest one or more pharmaceutical agents ] 12 and/or one or more nutraceuticaJ agents 122 within a given time period. Accordingly, in some embodiments, an input 104 may be associated with the selection of one or more pharmaceutical agents 1 12 and/or one or more nutraceutical agents 122 that are compatible with each other and/or that do not contraindicate each other. In some embodiments, an input 104 may be associated with the selection of one or more pharmaceutical agents 1 12 and/or one or more nutraceutical agents 122 that act in a synergistic manner when administered to a non-human individual 108.

At operation 306, the accepting operation 210 may include accepting the one or more parameters specifically associated with a physician input. In some embodiments, one or more accepting units 102 may accept the one or more parameters 106 specifically associated with a physician input 104.

In some embodiments, one or more physicians may input 104. one or more parameters 106 associated with an individual 108. In some embodiments, one or more parameters 106 may be input 104 by one or more physicians and one or more other sources. Other sources of input 104 include, but are not limited to, veterinarian input 104, pharmacist input 104, patient input 104, machine input 104, nutritionist inptit 104, and the like. In some embodiments, one or more physicians may examine the individual 108 and input 104 one or more parameters 106 associated with the individual 108 that are related to the examination. For example, one or more physicians may input 104 one or more parameters 106 associated with an individual's heart rate, skin condition, allergy status, sleep status, and the like. In some embodiments, one or more physicians may input 104 one or more parameters 106 associated with an individual 108 without ever seeing the individual 108. For example, in some embodiments, one or more physicians may review a medical chart associated with the individual 108 and input 104 parameters 106 based on the information contained in the medical chart. In some embodiments, one or more physicians may input 104 parameters 106 associated with an individual 108 from the physician's memory. In some embodiments, one or more physicians may input 104 parameters 106 associated with an individual 108 following consultation with a database and/or other source of information. In some embodiments, one or more physicians may input 104 parameters 106 associated with an individual 108 directly through use of a keyboard, a touch-screen, and the like. In some embodiments, one or more physicians may input 104 parameters 106 associated with an individual 108 remotely through use of numerous technologies that include, input 104 from a wireless device, the internet, an intranet, a telephone, a palm held organizer, input 104 from a personal digital assistant, input 104 from a web enabled cellular telephone, and the like.

At operation 308, the accepting operation 210 may include accepting the one or more parameters specifically associated with a veterinarian input. In some embodiments, one or more accepting units 102 may accept the one or more parameters 106 specifically associated with a veterinarian input 104.

In some embodiments, one or more veterinarians may input 104 one or more parameters 106 associated with a non-human individual 108. In some embodiments, one or more parameters 106 may be input 104 by one or more veterinarians and one or more other sources. Other sources of input 104 include, but are not limited to, physician input 104, pharmacist input 104, patient input 104, machine input 104, nutritionist input 104, and the like. In some embodiments, one or more veterinarians may examine a non- human individual 108 and input 104 one or more parameters 106 associated with the non- human individual 108 that are related to the examination. For example, one or more veterinarians may input 104 one or more parameters 106 associated with a non-human individual's heart rate, skin condition, allergy status, sleep status, and the like. In some embodiments, one or more veterinarians may input 104 one or more parameters 106 associated with a non-human individual 108 without ever seeing the non-human individual 108. For example, in some embodiments, one or more veterinarians may review a medical chart associated with the non-human individual 108 and input 104 parameters 106 based on the information contained in the medical chart. In some embodiments, one or more veterinarians may input 104 parameters 106 associated with a non-human individual 108 from the veterinarian's memory. In some embodiments, one or more veterinarians may input 104 parameters 106 associated with a non-human individual 108 following consultation with a database and/or other source of information. In some embodiments, one or more veterinarians may input 104 parameters 106 associated with a non-human individual 108 directly through use of a keyboard, a touchscreen, and the like. In some embodiments, one or more veterinarians may input 104 parameters 106 associated with a non-human individual 108 remotely through use of numerous technologies that include, input 104 from a wireless device, the internet, an intranet, a telephone, a palm held organizer, input 104 from a personal digital assistant, input 104 from a web enabled cellular telephone, and the like.

At operation 310, the accepting operation 210 may include accepting the one or more parameters specifically associated with a pharmacist input. In some embodiments, one or more accepting units 102 may accept the one or more parameters 106 specifically associated with a pharmacist input 104.

In some embodiments, one or more pharmacists may input 104 one or more parameters 106 associated with an individual 108. In some embodiments, one or more parameters 106 may be input 104 by one or more pharmacists and one or more other sources. Other sources of input 104 include, but are not limited to, physician input 104, veterinarian input 104, patient input 104, machine input 104, nutritionist input 104, and the like. In some embodiments, one or more pharmacists may consult with an individual 108 and input 104 one or more parameters 106 associated with the individual 108 that are related to the consultation. For example, one or more pharmacists may input 104 one or more parameters 106 associated with an individual's heart rate, skin condition, allergy status, sleep status, and the like. In some embodiments, one or more pharmacists may input 104 one or more parameters 106 associated with an individual 108 without ever seeing the individual 108. For example, in some embodiments, one or more pharmacists may receive information associated with the individual 108 and input 104 parameters 106 based on the received information. In some embodiments, one or more pharmacists may input 104 parameters 106 associated with an individual 108 from the pharmacist's memory. In some embodiments, one or more pharmacists may input 104 parameters 106 associated with an individual 108 following consultation with a database and/or other source of information. In some embodiments, one or more pharmacists may input 104 parameters 106 associated with an individual 108 directly through use of a keyboard, a touch-screen, and the like. In some embodiments, one or more pharmacists may input 104 parameters 106 associated with an individual 308 remotely through use of numerous technologies that include, input 104 from a wireless device, the internet, an intranet, a telephone, a palm held organizer, input 104 from a personal digital assistant, input 104 from a web enabled cellular telephone, and the like.

FIG. 4 illustrates alternative embodiments of the example operational flow 200 of FIG. 2. FIG. 4 illustrates example embodiments where the accepting operation 210 may include at least one additional operation. Additional operations may include an operation 402, operation 404, and/or operation 406.

At operation 402, the accepting operation 210 may include accepting the one or more parameters specifically associated with a patient input. In some embodiments, one or more accepting units 102 may accept the one or more parameters 106 specifically associated with a patient input 104.

In some embodiments, a patient may input 104 one or more parameters 106 associated with the patient. In some embodiments, one or more parameters 106 may be input 104 by the patient and one or more other sources. Other sources of input 104 include, but are not limited to, physician input 104, pharmacist input 104, patient input 104, machine input 104, nutritionist input 104, and the like. In some embodiments, a patient may input 104 one or more parameters 106 associated with the patient's heart rate, skin condition, allergy status, sleep status, and the like. In some embodiments, a patient may input 104 parameters 106 associated with the patient following consultation with a database and/or other source of information. In some embodiments, a patient may input 104 parameters 106 associated with the patient directly through use of a keyboard, a touch-screen, and the like. In some embodiments, a patient may input 104 parameters 106 associated with the patient remotely through use of numerous technologies that include, input 104 from a wireless device, the internet, an intranet, a telephone, a palm held organizer, input 104 from a personal digital assistant, input 104 from a web enabled cellular telephone, and the like. In some embodiments, a patient may input 104 parameters 106 associated with nutraceutica] agents 122 that are being administered to the patient. In some embodiments, a patient may input 104 parameters 106 associated with one or more times of administration of one or more nutraceutical agents 122.

At operation 404, the accepting operation 210 may include accepting the one or more parameters specifically associated with a machine input. In some embodiments, one or more accepting units 102 may accept the one or more parameters 106 specifically associated with a machine input 104.

In some embodiments, the one or more parameters 106 may include physical characteristics, metabolic characteristics, financial characteristics, and substantially any combination thereof. In some embodiments, such parameters 106 may include, alone or in combination and not limited to, an individual's height, weight, gender, kidney function, liver function, .level of physical fitness, age, allergic response, metabolic level (i.e., resting metabolic rate and/or activity-related metabolic rate), disease state, body fat percentage, personal habits (i.e., smoking, alcohol consumption, diet, illegal drug use, and the like), family health history, insurance coverage, food supplement usage, physical activities, sleep schedule, activity level, occupation, nutraceutical usage, non-prescription drug use, prescription drug use, pregnancy status, predisposition toward the development of a malady, genotype, phenotype, genetic predisposition, administration form of a nutraceutical agent 122, administration form of a pharmaceutical agent 112, mode of administration, time of administration, administration schedule, exposure to pathogens, potential exposure to pathogens, exposure to toxins, potential exposure to toxins, and the like. For example, in some embodiments, one or more parameters 106 associated with a human child may be input 104. Accordingly, such parameters 106 may provide for selection of one or more pharmaceutical agents 1 12 and/or one or more nutraceutical agents 122 that may be administered to a human child. In other embodiments, such parameters 106 may provide for selection against one or more pharmaceutical agents 112 and/or one or more nutraceutical agents 122 that should not be administered to a human child. Accordingly, in some embodiments, an input 104 may provide for the selection of one or more pharmaceutical agents 112 and/or one or more nutraceutical agents 122. However, in other embodiments, an input 104 may provide for selection against one or more pharmaceutical agents 112 and/or one or more nutraceutical agents 122. In some embodiments, parameters 106 may be input 104 that z^{^}elate to environmental factors such as, time, temperature, elevation, humidity, events, activities and the like. For example, an input 104 may include parameters 106 related to an individual 108 who is a mountain climber. Accordingly, one or more pharmaceutical agents 112 and/or one or more nutraceutical agents 122 may be selected that will not vaporize under lessened atmospheric pressure, that will not freeze, and/or that will not break. In some embodiments, one or more parameters 106 may be input 104 that relate to administration form and mode of administration of the one or more pharmaceutical agents 1 12 and/or one or more nutraceutical agents 122 to the individual 108. For example, in some embodiments, one or more parameters 106 may be input 104 that indicate that the individual 108 prefers to orally ingest pharmaceutical agents 1 12 and/or nutraceutical agents 122. In some embodiments, one or more parameters 106 may be input 104 that indicate that the individual 108 is to ingest one or more pharmaceutical agents 1 12 and/or one or more nutraceutical agents 122 within a given time period. Accordingly, in some embodiments, an input 104 may be associated with the selection of one or more pharmaceutical agents 112 and/or one or more nutraceutical agents 122 that are compatible with each other and/or that do not contraindicate each other. In some embodiments, an input 104 may be associated with the selection of one or more pharmaceutical agents 112 and/or one or more nutraceutical agents 122 that act in a synergistic manner when administered to an individual 108. In some embodiments, the machine is a diagnostic machine that has been utilized during examination of the individual 108.

At operation 406, the accepting operation 210 may include accepting the one or more parameters specifically associated with at least one of a nutritionist input, a regimen subscription input, a regimen specification input, a recommending party input, a recommending entity input, an advising party input, or an advising entity input. In some embodiments, one or more accepting units 102 may accept the one or more parameters associated with at least one of a nutritionist input 104, a regimen subscription input 104, a regimen specification input 104, a recommending party input 104, a recommending entity input 104, an advising party input 104, or an advising entity input 104.

In some embodiments, input 104 may include one or more parameters 106 associated with an individual 108. In some embodiments, input 104 may include one or more parameters associated with an individual 108 that are input 104 by one or more sources. Other sources of input 104 include, but are not limited to, physician input 104, veterinarian input 104, patient input 104, machine input 104, pharmacist input 104, regimen subscription input 104, regimen specification input 104, recommending parry input 104, recommending entity input 104, advising party input 104, advising entity input 104, and the like. In some embodiments, one or more sources of input 104 may consult with an individual 108 and input 104 one or more parameters 106 associated with the individual 108 that are related to the consultation. For example, one or more nutritionists may input 104 one or more parameters 106 associated with an individual's heart rate, skin condition, allergy status, sleep status, and the like. In some embodiments, one or more nutritionists may input 104 one or more parameters 106 associated with an individual 108 without ever seeing the individual 108. For example, in some embodiments, one or moi-e nutritionists may receive information associated with the individual 108 and input 104 parameters 106 based on the received information. In some embodiments, one or more nutritionists may input 104 parameters 106 associated with an individual 108 from the nutritionist's memory. In some embodiments, one or more nutritionists may input 104 parameters 106 associated with an individual 108 following consultation with a database and/or other source of information. In some embodiments, one or more nutritionists may input 104 parameters 106 associated with an individual 108 directly through use of a keyboard, a touch-screen, and the like. In some embodiments, one or more nutritionists may input 104 parameters 106 associated with an individual 108 remotely through use of numerous technologies that include, input 104 from a wireless device, the internet, an intranet, a telephone, a palm held organizer, input 104 from a personal digital assistant, input 104 from a web enabled cellular telephone, and the like. Input 104 may be associated with grocery stores, food supplement stores, personal trainers, coaches, clinics, hospitals, dental offices, veterinary offices, and the like.

FIG. 5 illustrates alternative embodiments of the example operational flow 200 of FIG. 2. FIG. 5 illustrates an example embodiment where the selecting operation 220 may include at least one additional operation. An additional operation may include an operation 502.

At operation 502, the selecting operation 220 may include selecting at least one of the one or more pharmaceutical agents in response to the selecting one or more nutraceutical agents in response to at least one of the one or more parameters specifically associated with the individual. In some embodiments, one or more selecting units 110 may select at least one of the one or more pharmaceutical agents 1 12 in response to the selecting one or more nutraceutical agents 122 in response to at least one of the one or more parameters 106 specifically associated with the individual 108.

In some embodiments, one or more pharmaceutical agents 112 may be selected based on the identity of the one or more nutraceutical agents 122 that were selected in response to at least one of the one or more parameters 106 specifically associated with an individual 108. For example, in some embodiments, one or more selecting units 1 10 may select one or more pharmaceutical agents 112 that act synergistically with one or more nutraceutical agents 122 when administered to an individual 108. For example, selective serotonin reuptake inhibitors (SSRI) may cause sexual dysfunction and decreased sex drive. Ginko Biloba was found to relieve many of these adverse side effects when coadministered with selective serotonin reuptake inhibitors (SSRI). In some embodiments, one or more selecting units 110 may select one or more pharmaceutical agents 1 12 that do not contraindicate one or more nutraceutical agents 122 when administered to an individual 108. For example, administration of St. John's Wort and/or 5 -hydroxy tryptophan in combination with pharmaceutical agents 112 that are selective serotonin reuptake inhibitors (SSRI) may cause hallucinations, fluctuating blood pressure, seizure, high temperatures, and irregular heart beat.

FIG. 6 illustrates alternative embodiments of the example operational flow 200 of FIG. 2. FIG. 6 illustrates example embodiments where the selecting operation 220 may include at least one additional operation. Additional operations may include an operation 602, and/or operation 604.

At operation 602, the selecting operation 220 may include selecting at least one of the one or more pharmaceutical agents in response to at least one condition specifically associated with the individual. In some embodiments, one or more selecting units 110 may select at least one of the one or more pharmaceutical agents 112 in response to at least one condition specifically associated with the individual 108.

In some embodiments, a condition specifically associated with an individual 108 may be an existing condition. In some embodiments, an existing condition is a medical condition. Examples of such medical conditions include, but are not limited to, viral infection, bacterial infection, fungal infection, diabetes, arthritis, gastrointestinal maladies, cancer, allergic responses, psychological disorders, osteoporosis, Alzheimer's disease, asthma, chronic fatigue syndrome, epilepsy, heart disease, hemochromatosis, hepatitis, stroke, food intolerance, and the like in substantially any combination. Accordingly, one or more pharmaceutical agents 1 12 may be selected to reduce or ameliorate the symptoms of a condition and/or to treat the condition directly. Numerous pharmaceutical agents 1 12 that may be selected in response to a condition are known (i.e., The Merck Index, 13^th Edition, An Encyclopedia of Chemicals, Drugs, and Biologicals, Merck & Co. Inc., Whitehouse Station, NJ 2001; Mosby's Drug Guide, Mosby, Inc., St. Louis, MO 2004; Remington: The Science and Practice of Pharmacy, 20^ll> Edition, Lippincott Williams & Wilkins, Philadelphia, PA 2000; Physicians' Desk Reference, 58^th Edition, Thompson, PDR, Montvale, NJ 2004; U.S. Patent No. 6,773,721, herein incorporated by reference).

In some embodiments, a condition specifically associated with an individual 108 may be a past condition. For example, one or more pharmaceutical agents 112 may be selected such that a condition, such as a medical condition, that an individual 108 was treated for in the past will be disallowed from reoccurring or the condition, or symptoms of the condition, may be reduced or minimized if the condition were to reoccur in the individual 108. For example, in some embodiments, one or more pharmaceutical agents 112 may be selected to prevent or reduce the consequences of a heart attack that may reoccur in an individual 108. In some embodiments, one or more pharmaceutical agents 112 may be selected to prevent or reduce the consequences of an epileptic seizure in an individual 108. Accordingly, one or more pharmaceutical agents 112 may be selected in response to numerous past conditions associated with the individual 108.

In some embodiments, a condition specifically associated with an individual 108 may be a future condition. For example, one or more pharmaceutical agents 112 may be selected such that a condition, such as a medical condition, that an individual 108 is predisposed to developing in the future may be disallowed from occurring or the condition, or symptoms of the condition, may be reduced or minimized if the condition were to occur in the individual 108. For example, bisphosphonates (alendronate, ibandronate and risedronate), calcitonin, estrogens, parathyroid hormone and raloxifene may be used for the prevention and/or treatment of osteoporosis. Accordingly, one or more pharmaceutical agents 1 12 may be selected in response to numerous future conditions associated with the individual 108. In some embodiments, one or more pharmaceutical agents 1 12 may be selected to prevent the occurrence of a future condition. For example, in some embodiments, the one or more pharmaceutical agents 1 12 may be vaccines that prevent or reduce infection by one or more infectious agents. In some embodiments, one or more pharmaceutical agents 112 may be selected in response to conditions that are cyclic. For example, in some embodiments, one or more pharmaceutical agents 1 12 may be selected in response to a woman's menstrual cycle. In other embodiments, one or more pharmaceutical agents 1 12 may be selected in response to a psychological malady, such as depression, that occurs in a cyclic manner. In other embodiments, one or more pharmaceutical agents 1 12 may be selected in response to hormonal changes that are expected to occur in the future, such as menopause.

In some embodiments, a condition specifically associated with an individual 108 may be an event or activity associated with an individual 108. For example, in some embodiments, one or more pharmaceutical agents 112 may be selected in response to a condition that is an event associated with an individual 108. For example, in some embodiments, an individual 108 may be expecting to participate in a sporting event. Accordingly, one or more pharmaceutical agents 1 12 may be selected in response to the event such that the one or more agents will not interfere with the performance of the individual 108. In other examples, the one or more pharmaceutical agents 112 may be selected to improve performance of the individual 108 in the event. In some embodiments, an individual 108 may expect to give a presentation. Accordingly, one or more pharmaceutical agents 112 may be selected that will not interfere with the performance of the individual 108 or that will improve performance of the individual 108 giving the presentation.

In some embodiments, a condition specifically associated with an individual 108 may be related to the environment in which the individual 108 resides or expects to reside. For example, if an individual 108 expects to travel on a boat, one or more pharmaceutical agents 112 may be selected that will not contribute to, or that will reduce or ameliorate, motion sickness. In some embodiments, the one or more pharmaceutical agents 112 may be selected based on the climactic environment in which an individual 108 resides or expects to reside. For example, one or more pharmaceutical agents 112 may be selected based on temperature, humidity, atmospheric pressure, and the like in substantially any combination. In some embodiments, the one or more pharmaceutical agents 1 12 may be selected based on the biological environment in which an individual 108 resides or expects to reside. For example, one or more pharmaceutical agents 1 12 may be selected based on the presence of allergens, pathogens, infectious agents, toxins, organisms and the like in substantially any combination.

In some embodiments, a condition specifically associated with an individual 108 may be a condition known to be associated with the individual 108 or a condition thought to be associated with an individual 108. For example, in some embodiments, one or more pharmaceutical agents 1 12 may be selected that can be used to treat an individual 108 with a diagnosed condition. In other embodiments, one or more pharmaceutical agents 112 may be selected that can be administered to an individual 108 with an undiagnosed condition with which the individual 108 was believed to be affected in the in the past, present or future.

At operation 604, the selecting operation 220 may include selecting at least one of the one or more pharmaceutical agents in response to at least one condition specifically associated with the individual wherein the at least one condition includes at least one of attentiveness, alertness, test performance, relaxation, pain, fever, anxiety, fall, injury, accident, bite, bleeding, inflammation, infection, drowsiness, insomnia, discomfort, stress, grooming, appearance, capability, performance, improvement, enhancement, curtailment, wellbeing, vitality, vigor, disability, phobia, malady, psychosis, environmental extremes, environmental exposure, dysfunction, disease symptom, chronic condition, mental acuity, emotional behavior, physical prowess, addiction, obsession, therapy, remedy, behavior, nutrition, diet, exercise, immunization, prevention, diagnosis, subscription, regimen, goal to be achieved, or treatment. In some embodiments, one or more selecting units 1 10 may select at least one of the one or more pharmaceutical agents 1 12 in response to at least one condition specifically associated with the individual wherein the at least one condition includes at least one of attentiveness, alertness, test performance, relaxation, pain, fever, anxiety, fall, injury, accident, bite, bleeding, inflammation, infection, drowsiness, insomnia, discomfort, stress, grooming, appearance, capability, performance, improvement, enhancement, curtailment, wellbeing, vitality, vigor, disability, phobia, malady, psychosis, environmental extremes, environmental exposure, dysfunction, disease symptom, chronic condition, mental acuity, emotional behavior, physical prowess, addiction, obsession, therapy, remedy, behavior, nutrition, diet, exercise, immunization, prevention, diagnosis, subscription, regimen, goal to be achieved, or treatment.

FlG. 7 illustrates alternative embodiments of the example operational flow 200 of FIG. 2. FIG. 7 illustrates example embodiments where the selecting operation 220 may include at least one additional operation. Additional operations may include an operation 702, operation 704, operation 706, operation 708, and/or operation 710.

At operation 702, the selecting operation 220 may include selecting at least one of the one or more pharmaceutical agents in response to at least one dosage specifically associated with the individual. In some embodiments, one or more selecting units 110 may select at least one of the one or more pharmaceutical agents 112 in response to at least one dosage specifically associated with the individual 108.

In some embodiments, one or more selecting units 110 may select one or more pharmaceutical agents 112 with regard to a volume of one or more of the pharmaceutical agents 1 12. For example, one or more selecting units 110 may select a first pharmaceutical agent 112 preferentially over a second pharmaceutical agent 112 if the first pharmaceutical agent 112 occupies less volume than the second pharmaceutical agent 112. In other examples, one or more selecting units 110 may select a first pharmaceutical agent 112 preferentially over a second pharmaceutical agent 112 if the first pharmaceutical agent 112 occupies more volume than the second pharmaceutical agent 1 12. Accordingly, one or more pharmaceutical agents 1 12 may be selected to increase or decrease the volume of the administration form of the one or more pharmaceutical agents 112 to promote administration to an individual 108.

In some embodiments, one or more selecting units 110 may select one or more pharmaceutical agents 112 with regard to the compatibility of the pharmaceutical agents 112 with each other or with the individual 108 at the dosage associated with the individual 108. For example, in some embodiments, one or more pharmaceutical agents 1 12 may be selected that are compatible with each other in response to dosage of at least one of the pharmaceutical agents 1 12 (i.e., see Mosby's Drug Guide, Mosby, Inc., St. Louis, MO, 2004). In some embodiments, one or more pharmaceutical agents 112 may be selected that are compatible with one or more nutraceutical agents 122 in response to dosage of at least one of the pharmaceutical agents 1 12. In some embodiments, one or more pharmaceutical agents 1 12 may be selected that are compatible with one or more nutraceutical agents 122 and one or more pharmaceutical agents 112 in response to dosage of at least one of the pharmaceutical agents 112. In some embodiments, one or more pharmaceutical agents 1 12 may be selected to act synergistically with another pharmaceutical agent 1 12 when administered to an individual 108 at a given dosage. In some embodiments, one or more pharmaceutical agents 112 may be selected to act synergistically with one or more nutraceutical agents 122 when administered to an individual 108 at a given dosage. In some embodiments, one or more pharmaceutical agents 1 12 may be selected to avoid synergistic interactions with one or more pharmaceutical agents 112 and/or one or more nutraceutical agents 122 when administered to an individual 108 at a given dosage. In some embodiments, one or more pharmaceutical agents 112 may be selected to counteract or reduce any negative side- effects of the one or more pharmaceutical agents 112 and/or one or more nutraceutical agents 122 when they are administered to an individual 108 at a given dosage. In some embodiments, one or more pharmaceutical agents 112 may be selected with regard to dosage so that they do not contraindicate additional components, such as food supplements, ingested by an individual 108. In some embodiments, one or more pharmaceutical agents 112 may be selected with regard to the price of the one or more pharmaceutical agents 112 with regard to one or more dosages associated with an individual 108. For example, in some embodiments, a pharmaceutical agent 112 may be commercially available at two or more dosages that are priced differently. Accordingly, in some embodiments, the one or more pharmaceutical agents 1 12 may be selected to achieve a desired dosage when administered to an individual 108 while reducing or minimizing the price associated with the one or more pharmaceutical agents 112.

At operation 704, the selecting operation 220 may include selecting at least one of the one or more pharmaceutical agents in response to dosage of at least one of the one or more pharmaceutical agents. In some embodiments, one or more selecting units 110 may select at least one of the one or more pharmaceutical agents 1 12 in response to dosage of at least one of the one or more pharmaceutical agents 1 12.

In some embodiments, one or more pharmaceutical agents 112 may be commercially available in preformulated administration forms. Accordingly, in some embodiments, one or more pharmaceutical agents 112 may be selected in response to administration forms that are commercially available. For example, in some embodiments, a pharmaceutical agent 112 may be commercially available in 100 milligram, 250 milligram, 500 milligram, 750 milligram, and 1000 milligram preformulated administration forms. In some instances, an individual 108 may be prescribed to ingest 750 milligram of a pharmaceutical agent 112. Accordingly, in some embodiments, a 750 milligram administration foπn of the pharmaceutical agent 112 may be selected. In other embodiments, a 250 milligram and a 500 milligram administration form of the pharmaceutical agent 112 may be selected. In other embodiments, a 250 milligram and five 100 milligram administration forms of the pharmaceutical agent 112 may be selected. Numerous combinations of administration forms may be selected. In some embodiments, administration forms may be selected with regard to price associated with the administration form. For example, in some embodiments, it may be less expensive to achieve a 750 milligram dosage of a pharmaceutical agent 112 by combining one 250 milligram administration form with five 100 milligram administration forms than selecting a single 750 milligram administration form.

In some embodiments, one or more pharmaceutical agents 112 may be selected with regard to administration forms for administration to an individual 108 over one or more periods of time. For example, it may be desirable to administer 1000 milligrams of a pharmaceutical agent 112 to an individual 108 over a ten hour time period. Accordingly, in some embodiments, a single 1000 milligram controlled release administration form may be selected. In other embodiments, ten 100 milligram administration forms may be selected and then packaged to be released at a rate of one 100 milligram administration form per hour over the ten hour period. Accordingly, numerous combinations of administration forms and timed release may be selected.

In some embodiments, one or more selecting units 110 may select one or more pharmaceutical agents 1 12 with regard to one or more volumes of one or more of the pharmaceutical agents 1 12 in the available administration forms. For example, one or more selecting units 1 10 may select a first pharmaceutical agent 1 12 preferentially over a second pharmaceutical agent 1 12 if the first pharmaceutical agent 1 12 occupies less volume than the second pharmaceutical agent 1 12 with regard to available administration forms. In other examples, one or more selecting units 1 10 may select a first pharmaceutical agent 1 12 preferentially over a second pharmaceutical agent 1 12 if the first pharmaceutical agent 1 12 occupies more volume than the second pharmaceutical agent 1 12 with regard to available administration forms. Accordingly, one or more pharmaceutical agents 1 12 may be selected to increase or decrease the volume of the one or more pharmaceutical agents 112 to promote administration to an individual 108. In some embodiments, one or more selecting units 110 may select one or more pharmaceutical agents 112 with regard to compatibility of the pharmaceutical agents 112 with each other and/or with the individual 108 when administered to the individual 108 at dosages corresponding to available administration forms of the pharmaceutical agents 112. For example, in some embodiments, one or more pharmaceutical agents 112 may be selected in response to administration forms available for the two or more pharmaceutical agents 112 (i.e., see Mosby's Drug Guide, Mosby, Inc., St. Louis, MO, 2004). In some embodiments, two or more pharmaceutical agents 1 12 may be selected to act synergistically with each other when administered to an individual 108 at available administration forms. In some embodiments, one or more pharmaceutical agents 112 may be selected to act synergistically with one or more pharmaceutical agents 1 12 and/or one or more nutraceutical agents 122 when administered to an individual 108 in available administration forms. In some embodiments, two or more pharmaceutical agents 112 may be selected to avoid synergistic interactions with each other when administered to an individual 108 in available administration forms. In some embodiments, one or more pharmaceutical agents 112 may be selected to avoid synergistic interactions with one or more pharmaceutical agents 3 12 and/or one or more nutraceutical agents 122 when administered to an individual 108 in available administration forms. In some embodiments, one or more pharmaceutical agents 112 may be selected to counteract or reduce any negative side-effects of the one or more pharmaceutical agents 1 12 and/or the one or more nutraceutical agents 122 when they are administered to an individual 108 at an available dosage. In some embodiments, one or more pharmaceutical agents 112 may be selected with regard to available dosage so that they do not contraindicate additional components, such as food supplements, ingested by an individual 108. In some embodiments, one or more pharmaceutical agents 1 12 may be selected with regard to the price of the one or more pharmaceutical agents 112 with regard to one or more available dosages associated with the one or more pharmaceutical agents 1 12. For example, in some embodiments, a pharmaceutical agent 1 12 may be commercially available at two or more dosages that are priced differently. Accordingly, in some embodiments, the one or more pharmaceutical agents 112 may be selected to achieve a desired dosage when administered to an individual 108 while reducing or minimizing the price associated with the one or more pharmaceutical agents 112.

At operation 706, the selecting operation 220 may include selecting at least one of the one or more pharmaceutical agents in response to at least one time of administration. In some embodiments, one or more selecting units 110 may select at least one of the one or more pharmaceutical agents 112 in response to at least one time of administration.

In some embodiments, the at least one time of administration is a time when the one or more pharmaceutical agents 112 are to be administered to an individual 108 to provide for release of the one or more pharmaceutical agents 1 12 from the administration form at a specified time following administration. For example, in some embodiments, at least one of the one or more pharmaceutical agents 112 may be selected such that it is released from an administration form about one hour after being administered to an individual 108. In other embodiments, a first pharmaceutical agent 1 12 may be selected such that it is released from an administration form about one hour after being administered to an individual 108 and a second pharmaceutical agent 1 12 may be selected such that it is released from an administration form about two hours after being administered to the individual 108. Accordingly, one or more pharmaceutical agents 1 12 may be selected that are released from an administration form at a specified time following administration to an individual 108 and thereupon become functionally available to the individual 108. In some embodiments, two or more incompatible pharmaceutical agents 112 and/or niitraceutical agents 122 may be administered to an individual 108 at the same time without adverse consequences by providing for release of the incompatible pharmaceutical agents 1 12 and/or nutraceiitical agents 122 at different times such that they do not contraindicate each other. In some embodiments, two or more pharmaceutical agents 1 12 that act synergistically may be coadministered to an individual 108 such that they are released at substantially the same time to provide for synergistic action of the two or more pharmaceutical agents 112 with regard to the individual 108. In some embodiments, one or more pharmaceutical agents 1 12 and one or more nutraceutical agents 122 that act synergistically may be coadministered to an individual 108 such that they are released at substantially the same time to provide for synergistic action with regard to the individual 108. Substantially any combination of pharmaceutical agents 112, nutraceutical agents 122, dosages, and release times may be selected.

In some embodiments, the at least one time of administration is relative to a time or event preceding or following administration of one or more pharmaceutical agents 112 to an individual 108. Accordingly, one or more pharmaceutical agents 112 may be selected that are released from an administration form at a relative time following administration to an individual 108 and thereupon become functionally available to the individual 108. For example, in some embodiments, two or more pharmaceutical agents 112 may be coadministered to an individual 108 such that a first pharmaceutical agent 112 is released from the administration form and a second pharmaceutical agent 112 is released from the administration form at a second time that is relative to the time of release of the first pharmaceutical agent 112. Accordingly, in some -embodiments, two or more incompatible pharmaceutical agents 112 may be administered to an individual 108 at the same time without adverse consequences by providing for release of the incompatible pharmaceutical agents 112 at different times such that they do not contraindicate each other. In some embodiments, two or more pharmaceutical agents 112 that act synergistically may be coadministered to an individual 108 such that they are released at substantially the same time to provide for synergistic action of the two or more pharmaceutical agents 112 with regard to the individual 108. In some embodiments, dosages of the two or more pharmaceutical agents 112 may be altered in a relative manner. For example, in some embodiments, the dosage of two or more pharmaceutical agents 1 12 may be calibrated relative to time of day. In other embodiments, the dosage of two or more pharmaceutical agents 1 12 may be calibrated relative to hormonal cycles. In other embodiments, the dosage of two or more pharmaceutical agents 1 12 may be calibrated relative to circadian rhythms. Such methods may also be used with regard to one or more nutraceutical agents 122. Accordingly, substantially any combination of pharmaceutical agents 1 12, nutraceutical agents 122, dosages, and release times may be selected relative to a time, event and/or the like.

At operation 708, the selecting operation 220 may include selecting at least one of the one or more pharmaceutical agents in response to two or more times of administration within a time period. In some embodiments, one or more selecting units 1 10 may select at least one of the one or more pharmaceutical agents 112 in response to two or more times of administration within a time period.

In some embodiments, a time period is defined as being a discrete amount of time. For example, in some embodiments, a time period may be defined in seconds, minutes, hours, days, months, years and substantially any combination thereof. In some embodiments, a time period may be defined as being an amount of time that is relative to a measurable quantity and/or event. For example, in some embodiments, a time period may be determined based on the concentration of a pharmaceutical agent 112 that was previously administered to an individual 108. Accordingly, in some embodiments, a first pharmaceutical agent 112 may be administered to an individual 108 and a second pharmaceutical agent 1 12 may be administered to the same individual 108 when the concentration of the first pharmaceutical agent 112 associated with the individual 108 either reaches a certain level or decreases to a certain level. Numerous combinations of discrete and/or relative amounts of time may be used during the selection of at least one of two or more pharmaceutical agents 112. In some embodiments, at least one of the two or more pharmaceutical agents 112 may be selected based on the identity of a second pharmaceutical agent 1 12 that is to be administered to an individual 108 within a time period in which the first pharmaceutical agent 1 12 is still present and/or functionally active in association with an individual 108. For example, in some embodiments, a first pharmaceutical agent 1 12 is selected such that it does not contraindicate a second pharmaceutical agent 1 12 that is to be administered to the individual 108 within a time period when the first and second pharmaceutical agents 1 12 are both present and/or functionally active in association with the individual 108. In some embodiments, the second pharmaceutical agent 1 12 is selected such that it does not contraindicate a first pharmaceutical agent 1 12 that is present and/or functionally active in association with the individual 108. In some embodiments, a first pharmaceutical agent 112 is selected such that it will act in a synergistic manner with a second pharmaceutical agent 1 12 that is to be administered to the individual 108 within a time period when the first and second pharmaceutical agents 1 12 are both present and/or functionally active in association with the individual 108. In some embodiments, the second pharmaceutical agent 112 is selected such that it will act in a synergistic manner with a first pharmaceutical agent 112 that is present and/or functionally active in association with the individual 108. In addition, in some embodiments, such methods may be used with regard to one or more nutraceutical agents 122 and/or combinations of one or more pharmaceutical agents 112 with one or more nutraceutical agents 122.

At operation 71O₃ the selecting operation 220 may include selecting at least one of the one or more pharmaceutical agents in response to one or more sites of administration specifically associated with the individual. In some embodiments, one or more selecting units 110 may select at least one of the one or more pharmaceutical agents 112 in response to one or more sites of administration specifically associated with the individual 108.

One or more pharmaceutical agents 112 may be administered at numerous sites associated with an individual 108. Examples of such sites include, but are not limited to, the eyes, ears, nose, skin, mouth, stomach, intestine, rectum, vagina, vascular system, pulmonary system, gastrointestinal system, urinary system and lymphatic system. In some embodiments, one or more pharmaceutical agents 112 may be administered at a first site associated with an individual 108 in preference to a second site associated with an individual ]08. For example, in some embodiments, it may be desirable to administer a pharmaceutical agent 112 that is acid labile by injection into the vascular system in preference to oral administration which may expose the pharmaceutical agent 112 to acidic conditions. Accordingly, in some embodiments, one or more pharmaceutical agents 1 12 may be selected based on the physical and chemical characteristics of the one or more pharmaceutical agents 1 12 and where the one or more pharmaceutical agents 112 will be administered to an individual 108. In some embodiments, one or more pharmaceutical agents J 12 may be selected in response to the site of action of the one or more pharmaceutical agents 1 12 on an individual 1OS. For example, in some embodiments, an adhesive patch may be used to administer one or more pharmaceutical agents 1 12 for the treatment of a malady associated with the skin. In some embodiments, one or more first pharmaceutical agents 1 12 may be selected for administration to a first site associated with an individual 108 and one or more second pharmaceutical agents 1 12 may be selected such that the second pharmaceutical agents 112 facilitate administration of the first pharmaceutical agents 112, do not contraindicate the first pharmaceutical agents 3 12, act synergistically with the first pharmaceutical agents 112, are administered to a second site associated with the individual 108, and/or substantially any combination thereof. In addition, in some embodiments, such methods may be used with regard to one or more nutraceutical agents 122 and/or combinations of one or more pharmaceutical agents 1 12 with one or more nutraceutical agents 122.

FIG. 8 illustrates alternative embodiments of the example operational flow 200 of FIG. 2. FIG. 8 illustrates example embodiments where the selecting operation 220 may include at least one additional operation. Additional operations may include an operation 802, operation 804, operation 806, and/or operation 808.

At operation 802, the selecting operation 220 may include selecting at least one of the one or more pharmaceutical agents in response to one or more sites of release specifically associated with the individual. In some embodiments, one or more selecting units 3 10 may select at least one of the one or more pharmaceutical agents 112 in response to one or more sites of release specifically associated with the individual 108.

In some embodiments, one or more pharmaceutical agents 1 12 may be administered to an individual 108 at a first site and then released from the administration form in which the pharmaceutical agents 1 12 were administered at a second site associated with the individual 108. For example, in some embodiments, one or more pharmaceutical agents 1 12 may be administered to an individual 108 in an oral administration form which can be released in the small intestine of the individual 108. In examples of other embodiments, one or more pharmaceutical agents 1 12 may be released into the vascular system of an individual 108 following transdermal administration of the one or more pharmaceutical agents 1 12 to the individual 108. In some embodiments, two or more pharmaceutical agents 112 may be coadministered to an individual 108 such that they are released from their administration forms at two or more separate sites associated with the individual 108. For example, in some embodiments, a first and second pharmaceutical agent 112 may be coadministered to an individual 108 such that the first pharmaceutical agent 1 12 is substantially released from the administration form in the upper gastrointestinal tract and the second pharmaceutical agent 112 is substantially released from the administration form in the lower gastrointestinal tract. Accordingly, in some embodiments, two or more pharmaceutical agents 112 that are incompatible or that would contraindicate each may be coadministered to an individual 108 for release at different sites associated with the individual 108 and/or at different times. In addition, in some embodiments, such methods may be used with regard to one or more nutraceutical agents 122 and/or combinations of one or more pharmaceutical agents 112 with one or more nutraceutical agents 122.

At operation 804, the selecting operation 220 may include selecting at least one of the one or more pharmaceutical agents in response to one or more physiological characteristics specifically associated with the individual. In some embodiments, one or more selecting units 110 may select at least one of the one or more pharmaceutical agents 112 in response to one or more physiological characteristics specifically associated with the individual 108.

Numerous physiological characteristics may be associated with an individual 108. Examples of such characteristics include, but are not limited to, age, gender, disease state, allergic responses, activity-related metabolic rate, resting metabolic rate, liver function, kidney function, weight, body fat percentage, epithelial cell function, lung function, skin function, gastrointestinal tract function, and substantially any combination thereof. Methods to predict drug response and to assess and correlate metabolism to drug dosage are known (i.e., International Publication Numbers: WO 03/084395 and WO 2005/041 105; U.S. Patent Nos. 6,317,719 and 6,087,090, herein incorporated by reference). Numerous assays may be used to assess the ability of an individual 108 to metabolize one or more pharmaceutical agents 1 12. In some embodiments, enzyme activities may be assessed to determine the ability of an individual 108 to metabolize one or more pharmaceutical agents 1 12. Examples of such enzyme systems and activities that may be assessed include, but are not limited to, the cytochrome P450 monooxygenase system, the flavin-containing monooxygenase system, alcohol dehydrogenase, aldehyde dehydrogenase, monoamine oxidase, cooxidation by peroxidases, NADPH-cytochrome P450 reductase, the presence of reduced (ferrous) cytochrome P450, esterases, amidases, epoxide hydrolase, glutathione S-transferases, mercapturic acid biosynthesis, UDP- Glucoron(os)yltransferases, N-Acetyltransferases, amino acid N-acyl transferases and sulfotransferases. In some embodiments, first and second pharmaceutical agents 112 may be effective to treat the same condition associated with an individual 108. However, an individual 108 may be able to metabolize the first pharmaceutical agent 112 very quickly but metabolize a second pharmaceutical agent 112 more slowly. Accordingly, in some embodiments, the second pharmaceutical agent 112 may be selected for administration to the individual 108 to avoid higher relative metabolism of the first pharmaceutical agent 1 Yl by the individual 108. In some embodiments, an individual 108 may mount an adverse allergic response to one or more pharmaceutical agents 112. Accordingly, one or more pharmaceutical agents 112 may be selected to avoid or minimize allergic response to administration of the one or more pharmaceutical agents 112 to the individual 108. One or more pharmaceutical agents 112, and combinations of one or more pharmaceutical agents 112, may be selected in response to numerous physiological characteristics associated with an individual 108. In addition, in some embodiments, such methods may be used with regard to one or more nutraceutical agents 122 and/or combinations of one or more pharmaceutical agents 1 12 with one or more nutraceutical agents 122.^"

At operation 806, the selecting operation 220 may include selecting at least one of the one or more pharmaceutical agents in response to cost associated with at least one of the one or more pharmaceutical agents. In some embodiments, one or more selecting units 110 may select at least one of the one or more pharmaceutical agents 112 in response to cost associated with at least one of the one or more pharmaceutical agents 112. In some embodiments, two or more different pharmaceutical agents 112 may be used to treat the same or a similar condition associated with an individual 108. In some embodiments, it may preferable to select a first pharmaceutical agent 1 12 having a lower associated cost over a second pharmaceutical agent 1 12 having a higher associated cost for administration to an individual 108. In other embodiments, it may be preferable to select a first pharmaceutical agent 1 12 having a higher associated cost over a second pharmaceutical agent 1 12 having a lower associated cost for administration to an individual 108. In some embodiments, one or more pharmaceutical agents 1 12 may be selected in response to cost associated with the one or more pharmaceutical agents 112 and numerous additional considerations. Such additional considerations include, but are not limited to, allergic response, dosage, effectiveness, interaction with other pharmaceutical agents 1 12, interaction with other nutraceutical agents 122, and substantially any combination thereof.

At operation 808, the selecting operation 220 may include selecting at least one of the one or more pharmaceutical agents in response to compatibility of at least one of the pharmaceutical agents with another of the one or more pharmaceutical agents. In some embodiments, one or more selecting units 110 may select at least one of the one or more pharmaceutical agents 1 12 in response to compatibility of at least one of the pharmaceutical agents 1 12 with another of the one or more pharmaceutical agents 112.

In some embodiments, at least one of the pharmaceutical agents 1 12 is selected that does not interact with another of the one or more pharmaceutical agents 1 12. In some embodiments, at least one of the pharmaceutical agents 112 is selected to act in a synergistic manner with another of the one or more pharmaceutical agents 1 12. In some embodiments, at least one of the pharmaceutical agents 112 is selected to not coπtraindicate at least one of the one or more pharmaceutical agents 1 12.

FIG. 9 illustrates alternative embodiments of the example operational flow 200 of FIG. 2. FIG. 9 illustrates an example embodiment where the selecting operation 220 may include at least one additional operation. An additional operation may include operation 902.

At operation 902, the selecting operation 230 may include selecting at least one of the one or more nutraceutical agents in response to the selecting one or more pharmaceutical agents in response to at least one of the one or more. parameters specifically associated with the individual. In some embodiments, one or more selecting units 1 10 may select at least one of the one or more nutraceutical agents 122 in response to the selecting one or more pharmaceutical agents 1 12 in response to at least one of the one or more parameters 106 specifically associated with the individual 108.

In some embodiments, one or more nutraceutical agents 122 may be selected based on the identity of the one or more pharmaceutical agents 112 that were selected in response to at least one of the one or more parameters 106 specifically associated with an individual 108. For example, in some embodiments, one or more selecting units 110 may select one or more nutraceutical agents 122 that act synergistically with one or more pharmaceutical agents 112 when administered to an individual 108. For example, selective serotonin reuptake inhibitors (SSRI) may cause sexual dysfunction and decreased sex drive. Ginko Biloba was found to relieve many of these adverse side effects when coadministered with selective serotonin reuptake inhibitors (SSRI). In some embodiments, one or more selecting units 110 may select one or more nutraceutical agents 122 that do not contraindicate one or more pharmaceutical agents 112 when administered to an individual 108. For example, administration of St. John's Wort and/or 5-hydroxytryptophan in combination with pharmaceutical agents 1 12 that are selective serotonin reuptake inhibitors (SSRI) may cause hallucinations, fluctuating blood pressure, seizure, high temperatures, and irregular heart beat.

FIG. 10 illustrates alternative embodiments of the example operational flow 200 of FIG. 2. FIG. 10 illustrates example embodiments where the selecting operation 230 may include at least one additional operation. Additional operations may include an operation 1002, and/or operation 1004.

At operation 1002, the selecting operation 230 may include selecting at least one of the one or more nutraceutical agents in response to at least one condition specifically associated with the individual. In some embodiments, one or more selecting units 1 10 may select at least one of the one or more nutraceutical agents 122 in response to at least one condition specifically associated with the individual 108.

In some embodiments, a condition specifically associated with an individual 108 may be an existing condition. In some embodiments, an existing condition is a medical condition. Examples of such medical conditions include, but are not limited to, viral infection, bacterial infection, fungal infection, diabetes, arthritis, gastrointestinal maladies, cancer, allergic responses, psychological disorders, osteoporosis, Alzheimer's disease, asthma, chronic fatigue syndrome, epilepsy, heart disease, hemochromatosis, hepatitis, stroke, food intolerance, and the like in substantially any combination. Accordingly, one or more πutraceutical agents 122 may be selected to reduce or ameliorate the symptoms of a condition and/or to treat the condition directly. Numerous nutraceutical agents 122 that may be selected in response to a condition are known (i.e., Roberts et al., Nutraceuticals: The Complete Encyclopedia of Supplements, Herbs, Vitamins, and Healing Foods, l^s! Edition, Perigee Trade (2001); Rapport and Lockwood, Nutraceuticals, Pharmaceutical Press (2001); Wildman, Handbook of Nutraceuticals and Functional Foods, CRC Press, 1^st Edition, (2000); Eskin, Dictionary of Nutraceuticals and Functional Foods (Functional Foods and Nutraceuticals), CRC Press, (2005); The^' PDR Family Guide to Nutritional Supplements : An Authoritative A-to-Z Resource on the 100 Most Popular Nutritional Therapies and Nutraceuticals; Ballantine Books, 1^st Edition, (2001); Susan G. Wynn, Emerging Therapies: Using Herbs and Nutraceuticals for Small Animals, American Animal Hospital Assn Press (1999); U.S. Patent Nos. 7,045,159; 7,049,433; 7,041,840; 6,979,679; 6,962,720; 6,881 ,425; The Merck Index, 13^th Edition, An Encyclopedia of Chemicals, Drugs, and Biologicals, Merck & Co. Inc., Whitehouse Station, NJ (2001); Mosby's Drug Guide, Mosby, Inc., St. Louis, MO (2004); Remington: The Science and Practice of Pharmacy, 20^th Edition, Lippincott Williams & Wilkins, Philadelphia, PA (2000); Physicians' Desk Reference, 58^th Edition, Thompson, PDR, Montvale, NJ (2004); U.S. Patent No. 6,773,721 ; herein incorporated by reference).

In some embodiments, a condition specifically associated with an individual 108 may be a past condition. For example, one or more nutraceutical agents 122 may be selected such that a condition, such as a medical condition, that an individual 108 was treated for in the past will be disallowed from reoccurring or the condition, or symptoms of the condition, may be reduced or minimized if the condition were to reoccur in the individual 108. For example, in some embodiments, one or more nutraceutical agents 122 may be selected to prevent or reduce the consequences of a heart attack that may reoccur in an individual 108. In some embodiments, one or more nutraceutical agents 122 may be selected to prevent or reduce the consequences of an epileptic seizure in an individual 108. Accordingly, one or more nutraceutical agents 122 may be selected in response to numerous past conditions associated with the individual 108.

In some embodiments, a condition specifically associated with an individual 108 may be a future condition. For example, one or more nutraceutical agents 122 may be selected such that a condition, such as a medical condition, that an individual 108 is predisposed to developing in the future may be disallowed from occurring or the condition, or symptoms of the condition, may be reduced or minimized if the condition were to occur in the individual 108. Accordingly, one or more nutraceutical agents 122 may be selected in response to numerous future conditions associated with the individual 108. In some embodiments, one or more nutraceutical agents 122 may be selected to prevent the occurrence of a future condition. In some embodiments, one or more nutraceutical agents 122 may be selected in response to conditions that are cyclic. For example, in some embodiments, one or more nutraceutical agents 122 may be selected in response to a woman's menstrual cycle. In other embodiments, one or more nutraceutical agents 122 may be selected in response to a psychological malady, such as depression, that occurs in a cyclic manner. In other embodiments, one or more nutraceutical agents 122 may be selected in response to hormonal changes that are expected to occur in the future, such as menopause.

In some embodiments, a condition specifically associated with an individual 108 may be an event or activity associated with an individual 108. For example, in some embodiments, one or more nutraceutical agents 122 may be selected in response to a condition that is an event associated with an individual 108. For example, in some embodiments, an individual 108 may be expecting to participate in a sporting event. Accordingly, one or more nutraceutical agents 122 may be selected in response to the event such that the one or more agents will not interfere with the performance of the individual 108. In other examples, the one or more nutraceutical agents 122 may be selected to improve performance of the individual 108 in the event. In some embodiments, an individual 108 may expect to give a presentation. Accordingly, one or more irutraceutical agents 122 may be selected that will not interfere with the performance of the individual 108 or that will improve performance of the individual 108 giving the presentation.

In some embodiments, a condition specifically associated with an individual 108 may be related to the environment in which the individual 108 resides or expects to reside. For example, if an individual 108 expects to travel on a boat, one or more nutraceutical agents 122 may be selected that will not contribute to, or that will reduce or ameliorate, motion sickness. In some embodiments, the one or more nutraceutical agents 122 may be selected based on the climactic environment in which an individual 108 resides or expects to reside. For example, one or more nutraceutical agents 122 may be selected based on temperature, humidity, atmospheric pressure, and the like in substantially any combination. In some embodiments, the one or more nutraceutical agents 122 may be selected based on the biological environment in which an individual 108 resides or expects to reside. For example, one or more nutraceutical agents 122 may be selected based on the presence of allergens, pathogens, infectious agents, toxins, organisms and the like in substantially any combination.

In some embodiments, a condition specifically associated with an individual 108 may be a condition known to be associated with the individual 108 or a condition thought to be associated with an individual 108. For example, in some embodiments, one or more nutraceutical agents 122 may be selected that can be used to treat an individual 108 with a diagnosed condition. In other embodiments, one or more nutraceutical agents 122 may be selected that can be administered to an individual 108 with an undiagnosed condition with which the individual 108 was believed to be affected in the in the past, present or future. For example, in some embodiments, 5 -hydroxy tryptophan, s-adenosylmethionine, St. John's wort, Kava kava, Ginko biloba, melatonin, and/or substantially any combination thereof may be a selected for administration to an individual 108 to reduce or eliminate symptoms associated with depression. In other embodiments, glucosamine and/or chondroitan may be selected for administration to an individual 108 to rebuild cartilage that cushions and protects joints. In some embodiments, small quantitites of lithium may be used to reduce or eliminate symptoms associated with manic/depressive (bipolar) and depressive disorders associated with an individual 108. In other embodiments, small amounts of lithium or choline in combination with vitamin supplements may be used to reduce or eliminate symptoms associated with . manic/depressive (bipolar) and depressive disorders associated with an individual 108.

At operation 1004, the selecting operation 230 may include selecting at least one of the one or more πutraceutical agents in response to at least one condition specifically associated with the individual wherein the at least one condition includes at least one of attentiveness, alertness, test performance, relaxation, pain, fever, anxiety, fall, injury, accident, bite, bleeding, inflammation, infection, drowsiness, insomnia, discomfort, stress, grooming, appearance, capability, performance, improvement, enhancement, curtailment, wellbeing, vitality, vigor, disability, phobia, malady, psychosis, environmental extremes, environmental exposure, dysfunction, disease symptom, chronic condition, mental acuity, emotional behavior, physical prowess, addiction, obsession, therapy, remedy, behavior, nutrition, diet, exercise, immunization, prevention, diagnosis, subscription, regimen, goal to be achieved, or treatment. In some embodiments, one or more selecting units 1 10 may include selecting at least one of the one or more nutraceutical agents 122 in response to at least one condition specifically associated with the individual 108 wherein the at least one condition includes at least one of attentiveness, alertness, test performance, relaxation, pain, fever, anxiety, fall, injury, accident, bite, bleeding, inflammation, infection, drowsiness, insomnia, discomfort, stress, grooming, appearance, capability, performance, improvement, enhancement, curtailment, wellbeing, vitality, vigor, disability, phobia, malady, psychosis, environmental extremes, environmental exposure, dysfunction, disease symptom, chronic condition, mental acuity, emotional behavior, physical prowess, addiction, obsession, therapy, remedy, behavior, nutrition, diet, exercise, immunization, prevention, diagnosis, subscription, regimen, goal to be achieved, or treatment. Accordingly, in some embodiments, at least one of the one or more nutraceutical agents 122 may be selected in response to an existing condition. In some embodiments, at least one of the one or more nutraceutical agents 122 may be selected in reponse to a goal that is to be achieved in the future. Examples of such goals include, but are not limited to, attentiveness, alertness, increased test performance, relaxation, and the like.

FIG. 11 illustrates alternative embodiments of the example operational flow 200 of FIG. 2. FIG. 1 1 illustrates example embodiments where the selecting operation 230 may include at least one additional operation. Additional operations may include an operation 1 102, operation 1 104, operation 1 106, operation 1 108, and/or operation 1 1 10. At operation 1 102, the selecting operation 230 may include selecting at least one of the one or more nutraceutical agents in response to at least one dosage specifically associated with the individual. In some embodiments, one or more selecting units 110 may select at least one of the one or more nutraceutical agents 122 in response to at least one dosage specifically associated with the individual 108.

In some embodiments, one or more selecting units 1 10 may select one or more nutraceutical agents 122 with regard to a volume of one or more of the nutraceutical agents 122. For example, one or more selecting units 110 may select a first nutraceutical agent 122 preferentially over a second nutraceutical agent 122 if the first nutraceutical agent 122 occupies less volume than the second nutraceutical agent 122. In other examples, one or more selecting units 110 may select a first nutraceutical agent 122 preferentially over a second nutraceutical agent 122 if the first nutraceutical agent 122 occupies more volume than the second nutraceutical agent 122. Accordingly, one or more nutraceutical agents 122 may be selected to increase or decrease the volume of the administration form of the one or more nutraceutical agents 122 to promote administration to an individual 108.

In some embodiments, one or more selecting units 110 may select one or more nutraceutical agents 122 with regard to the compatibility of the nutraceutical agents 122 with each other or with the individual 108 at the dosage associated with the individual 108. For example, in some embodiments, two or more nutraceutical agents 122 may be ^• selected that are compatible with each other in response to dosage of at least one of the nutraceutical agents 122. In some embodiments, one or more nutraceutical agents 122 may be selected to act synergistically with each other when administered to an individual 108 at a given dosage. In some embodiments, one or more nutraceutical agents 122 may be selected to avoid synergistic interactions with each other when administered to an individual 108 at a given dosage. In some embodiments, one or more nutraceutical agents 122 may be selected to counteract or reduce any negative side-effects of the one or more nutraceutical agents 122 when they are administered to an individual 108 at a given dosage. In some embodiments, one or more nutraceutical agents 122 may be selected with regard to dosage so that they do not contraiπdicate additional components, such as pharmaceuticals and/or food supplements, ingested by an individual 108. In some embodiments, one or more nutraceutical agents 122 may be selected with regard to the price of the one or more nutraceutical agents 122 with regard to one or more dosages associated with an individual 108. For example, in some embodiments, a nutraceutical agent 122 may be commercially available at two or more dosages that are priced differently. Accordingly, in some embodiments, the one or more nutraceutical agents 122 may be selected to achieve a desired dosage when administered to an individual 108 while reducing or minimizing the price associated with the one or more nutraceutical agents 122. In addition, in some embodiments, such methods may be used with regard to one or more pharmaceutical agents 112 and/or combinations of one or more pharmaceutical agents 1 12 with one or more nutraceutical agents 122.

At operation 1104, the selecting operation 230 may include selecting at least one of the one or more nutraceutical agents in response to dosage of at least one of the one or more nutraceutical agents. In some embodiments, one or more selecting units 110 may select the one or more nutraceutical agents 122 in response to dosage of at least one of the one or more nutraceutical agents 122.

In some embodiments, one or more nutraceutical agents 122 may be commercially available in preformulated administration forms. Accordingly, in some embodiments, one or more nutraceutical agents 122 may be selected in response to administration forms that are commercially available. For example, in some embodiments, a nutraceutical agent 122 may be commercially available in 100 milligram, 250 milligram, 500 milligram, 750 milligram, and 1000 milligram preformulated administration forms. In some instances, an individual 108 may be instructed to ingest 750 milligram of a nutraceutical agent 122. Accordingly, in some embodiments, a 750 milligram administration form of the nutraceutical agent 122 may be selected. In other embodiments, a 250 milligram and a 500 milligram administration form of the nutraceutical agent 122 may be selected. In other embodiments, a 250 milligram and five 100 milligram administration forms of the nutraceutical agent 122 may be selected. Numerous combinations of administration forms may be selected. In some embodiments, administration forms may be selected with regard to price associated with the administration form. For example, in some embodiments, it may be less expensive to achieve a 750 milligram dosage of a nutraceutical agent 122 by combining one 250 milligram administration form with five 100 milligram administration forms than selecting a single 750 milligram administration form.

In some embodiments, one or more nutraceutical agents 122 may be selected for administration to an individual 108 over one or more periods of time. For example, it may be desirable to administer 1000 milligrams of a nutraceutical agent 122 to an individual 108 over a ten hour time period. Accordingly, in some embodiments, a single 1000 milligram controlled release administration form may be selected. In other embodiments, ten 100 milligram dosages may be selected and then packaged into a single administration form to be released at a rate of one 100 milligram dosage per hour over the ten hour period. Accordingly, numerous combinations of administration forms and timed release may be selected.

In some embodiments, one or more selecting units 1 10 may select one or more nutraceutical agents 122 with regard to one or more volumes of one or more of the nutraceutical agents 122 in the available administration forms. For example, one or more selecting units 110 may select a first nutraceutical agent 122 preferentially over a second nutraceutical agent 122 if the first nutraceutical agent 122 occupies less volume than the second nutraceutica] agent 122 with regard to available administration forms. In other examples, one or more selecting units 110 may select a first nutraceutical agent 122 preferentially over a second nutraceutical agent 122 if the first nutraceutical agent 122 occupies more volume than the second nutraceutical agent 122 with regard to available administration forms. Accordingly, one or more nutraceutical agents 122 may be selected to increase or decrease the volume of the one or more nutraceutical agents 122 to promote administration to an individual 108.

In some embodiments, one or more selecting units 110 may select at least one of one or more nutraceutical agents 122 with regard to compatibility of the nutraceutical agents 122 with each other, with one or more pharmaceutical agents 112, and/or with the individual 108 when administered to the individual 108 at dosages corresponding to available administration forms of the nutraceutical agents 122. For example, in some embodiments, one or more nutraceutical agents 122 may be selected in response to administration forms available for the one or more nutraceutical agents 122. In some embodiments, two or more nutraceutical agents 122 may be selected to act synergistically with each other when administered to an individual 108 at available administration forms. In some embodiments, two or more nutraceutical agents 122 may be selected to avoid synergistic interactions with each other when administered to an individual 108 as available administration forms. In some embodiments, at least one of one or more nutraceutical agents 122 may be selected to counteract or reduce any negative side-effects of the one or more nutraceutical agents 122 when they are administered to an individual ^' 108 at an available dosage. In some embodiments, one or more nutraceutical agents 122 may be selected with regard to available dosage so that they do not contraindicate additional components, such as pharmaceutical agents 112 and/or food supplements, ingested by an individual 108. In some embodiments, one or more nutraceutical agents 122 may be selected with regard to the price of the one or more nutraceutical agents 122 with regard to one or more available dosages associated with the one or more nutraceutical agents 122. For example, in some embodiments, a nutraceutical agent 122 may be commercially available at two or more dosages that are priced differently. Accordingly, in some embodiments, the one or more nutraceutical agents 122 may be selected to achieve a desired dosage when administered to an individual 108 while reducing or minimizing the price associated with the one or more nutraceutical agents 122. In addition, in some embodiments, such methods may be used with regard to one or more pharmaceutical agents 112 and/or combinations of one or more pharmaceutical agents 112 with one or more nutraceutical agents 122.

At operation 1 106, the selecting operation 230 may include selecting at least one of the one or more nutraceutical agents in response to at least one time of administration. In some embodiments, one or more selecting units 1 10 may select at least one of the one or more nutraceutical agents 122 in response to at least one time of administration

In some embodiments, the at least one time of administration is a time when the one or more nutraceutical agents 122 are to be administered to an individual 108 to provide for release of the one or more nutraceutical agents 122 from the administration form at a specified time following administration. For example, in some embodiments, at least one of the one or more nutraceutical agents 122 may be selected such that it is released from an administration form about one hour after being administered to an individual 108. In other embodiments, a first nutraceutical agent 122 may be selected such that it is released from an administration form about one hour after being administered to an individual 108 and a second nutraceutical agent 122 may be selected such that it is released from an administration form about two hours after being administered to the individual 108. Accordingly, one or more nutraceutical agents 122 may be selected that are released from an administration form at a specified time following administration to an individual 108 and thereupon become functionally available to the individual 108. In some embodiments, two or more incompatible nutraceutical agents 122 may be administered to an individual 108 at the same time without adverse consequences by providing for release of the incompatible nutraceutical agents 122 at different times such that they do not contraindicate each other. In some embodiments, two or more nutraceutical agents 122 that act synergisticalϊy may be coadministered to an individual 108 such that they are released at substantially the same time to provide for synergistic action of the two or more nutraceutical agents 122 with regard to the individual 108. Substantially any combination of nutraceutical agents 122, dosages and release times may be selected.

In some embodiments, the at least one time of administration is relative to a time or event preceding or following administration of one or more nutraceutical agents 122 to an individual 108. Accordingly, one or more nutraceutical agents 122 may be selected that are released from an administration form at a relative time following administration to an individual 108 and thereupon become functionally available to the individual 108. For example, in some embodiments, two or more nutraceutical agents 122 may be coadministered to an individual 108 such that a first nutraceutical agent 122 is released from the administration form and a second nutraceutical agent 122 is released from the administration form at a second time that is relative to the time of release of the first nutraceutical agent 122. Accordingly, in some embodiments, two or more incompatible nutraceutical agents 122 may be administered to an individual 108 at the same time without adverse consequences by providing for release of the incompatible nutraceutical agents 122 at different times such that they do not contraindicate each other. In some embodiments, two or more nutraceutical agents 122 that act synergistically may be coadministered to an individual 108 such that they are released at substantially the same time to provide for synergistic action of the two or more nutraceutical agents 122 with regard to the individual 108. In some embodiments, dosages of the two or more nutraceutical agents 122 may be altered in a relative manner. For example, in some embodiments, the dosage of two or more nutraceutical agents 122 may be calibrated relative to time of day. In other embodiments, the dosage of two or more nutraceutical agents 122 may be calibrated relative to hormonal cycles. In other embodiments, the dosage of two or more nutraceutical agents 122 may be calibrated relative to circadian rhythms. In addition, in some embodiments, such methods may be used with regard to one or more pharmaceutical agents 112 and/or combinations of one or more pharmaceutical agents 112 with one or more nutraceutical agents 122. Accordingly, substantially any combination of nutraceutical agents 122, pharmaceutical agents 1 12, dosages, and release times may be selected relative to a time, event and/or the like. In addition, in some embodiments, such methods may be used with regard to one or more pharmaceutical agents 1 12 and/or combinations of one or more pharmaceutical agents 112 with one or more nutraceutical agents 122.

At operation 1108, the selecting operation 230 may include selecting at least one of the one or more nutraceutical agents in response to two or more times of administration within a time period. In some embodiments, one or more selecting units 110 may select at least one of the one or more nutraceutical agents 122 in response to two or more times of administration within a time period.

In some embodiments, a time period is defined as being a discrete amount of time. For example, in some embodiments, a time period may be defined in seconds, minutes, hours, days, months, years and substantially any combination thereof. In some embodiments, a time period may be defined as being an amount of time that is relative to a measurable quantity and/or event. For example, in some embodiments, a time period may be determined based on the concentration of a nutraceutical agent 122 that was previously administered to an individual 108. Accordingly, in some embodiments, a first nutraceutical agent 122 may be administered to an individual 108 and a second, nutraceutical agent 122 may be administered to the same individual 108 when the concentration of the first nutraceutical agent 122 associated with the individual 108 either reaches a certain level or decreases to a certain level. Numerous combinations of discrete and/or relative amounts of time may be used during the selection of at least one of the one or more nutraceutical agents 122. In some embodiments, at least one of the one or more nutraceutical agents 122 may be selected based on the identity of a second nutraceutical agent 122 that is to be administered to an individual 108 within a time period in which the first nutraceutical agent 122 is still present and/or functionally active in association with an individual 108. For example, in some embodiments, a first nutraceutical agent 122 is selected such that it does not contraindicate a second nutraceutical agent 122 that is to be administered to the individual 108 within a time period when the first and second nutraceutical agents 122 are both present and/or functionally active in association with the individual 108. In some embodiments, the second nutraceutical agent 122 is selected such that it does not contraindicate a first nutraceutical agent 122 that is present and/or functionally active in association with the individual 108. In some embodiments, a first nutraceutical agent 122 is selected such that it will act in a synergistic manner with a second nutraceutical agent 122 that is to be administered to the individual 108 within a time period when the first and second nutraceutical agents 122 are both present and/or functionally active in association with the individual 108. In some embodiments, the second nutraceutical agent 122 is selected such that it will act in a synergistic manner with a first nutraceutical agent 122 that is present and/or functionally active in association with the individual 108. In addition, in some embodiments, such methods may he used with regard to one or more pharmaceutical agents 112 and/or combinations of one or more pharmaceutical agents 112 with one or more nutraceutical agents 122. In some embodiments, such methods may be used with regard to one or more pharmaceutical agents 1 12 and/or combinations of one or more pharmaceutical agents 1 12 with one or more nutraceutical agents 122.

At operation 1110, the selecting operation 230 may include selecting at least one of the one or more nutraceutical agents in response to one or more sites of administration specifically associated with the individual. In some embodiments, one or more selecting units 1 10 may select at least one of the one or more ^"nutraceutical agents 122 in response to one or more sites of administration specifically associated with the individual 108. One or more nutraceutical agents 122 may be administered at numerous sites associated with an individual 108. Examples of such sites include, but are not limited to, the eyes, ears, nose, skin, mouth, stomach, intestine, rectum, vagina, vascular system, pulmonary system, gastrointestinal system, urinary system and lymphatic system. In some embodiments, one or more nutraceutical agents 122 may be administered at a first site associated with an individual 108 in preference to a second site associated with an individual 108. For example, in some embodiments, it may be desirable to administer a nutraceutical agent 122 that is acid labile by injection into the vascular system in preference to oral administration which may expose the nutraceutical agent 122 to acidic conditions. Accordingly, in some embodiments, one or more nutraceutical agents 122 may be selected based on the physical and chemical characteristics of the one or more nutraceutical agents 122 and where the one or more nutraceutical agents 122 will be administered to an individual 108. In some embodiments, one or more nutraceutical agents 122 may be selected in response to the site of action of the one or more nutraceutical agents 122 on an individual 108. For example, in some embodiments, an adhesive patch may be used to administer one or more nutraceutical agents 122 for the treatment of a malady associated with the skin. In some embodiments, one or more first nutraceutical agents 122 may be selected for administration to a first site associated with an individual 108 and one or more second nutraceutical agents 122 may be selected such that the second nutraceutical agents 122 facilitate administration of the first nutraceutical agents 122, do not contraindicate the first nutraceutical agents 122, act synergistically with the first nutraceutical agents 122, are administered to a second site associated with the individual 108, and/or substantially any combination thereof. In some embodiments, such methods may be used with regard to one or more pharmaceutical agents 112 and/or combinations of one or more pharmaceutical agents 112 with one or more nutraceutical agents 122.

FIG. 12 illustrates alternative embodiments of the example operational flow 200 of FIG. 2. FIG. 12 illustrates example embodiments where the selecting operation 230 may include at least one additional operation. Additional operations may include an operation 1202, operation 1204, operation 1206, and/or operation 1208. At operation 1202, the selecting operation 230 may include selecting at least one of the one or more nutraceutical agents in response to one or more sites of release specifically associated with the individual. In some embodiments, one or more selecting units 1 10 may select at least one of the one or more nutraceutical agents 122 in response to one or more sites of release specifically associated with the individual 108.

In some embodiments, one or more nutraceutical agents 122 may be administered to an individual 108 at a first site and then released from the administration form in which the nutraceutical agents 122 were administered at a second site associated with the individual 108. For example, in some embodiments, one or more nutraceutical agents 122 may be administered to an individual 108 in an oral administration form which can be released in the small intestine of the individual 108. In examples of other embodiments, one or more nutraceutical agents 122 may be released into the vascular system of an individual 108 following transdermal administration of the one or more nutraceutical agents 122 to the individual 108. In some embodiments, two or more nutraceutical agents 122 may be coadministered to an individual 108 such that they are released from their administration forms at two or more separate sites associated with the individual 108. For example, in some embodiments, a first and second nutraceutical agent 122 may be coadministered to an individual 108 such that the first nutraceutical agent 122 is substantially released from the administration form in the vipper gastrointestinal tract and the second nutraceutical agent 122 is substantially released from the administration form in the lower gastrointestinal tract. Accordingly, in some embodiments, two or more nutraceutical agents 122 that are incompatible or that would contraindicate each may be coadministered to an individual 108 for release at different sites associated with the individual 108 and/or at different times. In some embodiments, such methods may be used with regard to one or more pharmaceutical agents 112 and/or combinations of one or more pharmaceutical agents 1 12 with one or more nutraceutical agents 122.

At operation 1204., the selecting operation 230 may include selecting at least one ^' of the one or more nutraceutical agents in response to one or more physiological characteristics specifically associated with the individual. In some embodiments, one or more selecting units 1 10 may select at least one of the one or more nutraceutical agents 122 in response to one or more physiological characteristics specifically associated witli the individual 108.

Numerous physiological characteristics may be associated with an individual 108. Examples of such characteristics include, but are not limited to, age, gender, disease state, allergic responses, activity-related metabolic rate, resting metabolic rate, liver function, kidney function, weight, body fat percentage, epithelial cell function, lung function, skin function, gastrointestinal tract function, and substantially any combination thereof. Methods to predict drug response and to assess and correlate metabolism to drug dosage are known (i.e., International Publication Numbers: WO 03/084395 and WO 2005/041 105; U.S. Patent Nos. 6,317,719 and 6,087,090, herein incorporated by reference). Such methods may also be used to predict and to assess and correlate metabolism of a nutraceutical agent 122 by an individual 108. Accordingly, numerous assays may be used to assess the ability-of an individual 108 to metabolize one or more nutraceutical agents 122. In some embodiments, enzyme activities may be assessed to determine the ability of an individual 108 to metabolize one or more nutraceutical agents 122. Examples of such enzyme systems and activities that may be assessed include, but are not limited to, the cytochrome P450 monooxygenase system, the flavin-containing monooxygenase system, alcohol dehydrogenase, aldehyde dehydrogenase, monoamine oxidase, cooxidation by peroxidases, NADPH-cy to chrome P450 reductase, the presence of reduced (ferrous) cytochrome P450, esterases, amidases, epoxide hydrolase, glutathione S-transferases, mercapturic acid biosynthesis, UDP- glucoron(os)yltransferases, N-Acetyltransferases, amino acid N-acyl transferases and sulfotransferases. In some embodiments, first and second nutraceutical agents 122 may be effective to treat the same condition associated with an individual 108. However, an individual 108 may be able to metabolize the first nutraceutical agent 122 very quickly but metabolize a second nutraceutical agent 122 more slowly. Accordingly, in some embodiments, the second nutraceutical agent 122 may be selected for administration to the individual 108 to avoid higher relative metabolism of the first nutraceutical agent 122 by the individual 108. In some embodiments, an individual 108 may mount an adverse allergic response to one or more nutraceutical agents 122. Accordingly, one or more nutraceutical agents 122 may be selected to avoid or minimize allergic response to administration of the one or more nutraceutical agents 122 to the individual 108. One or more nutraceutical agents 122, and combinations of one or more nutraceutical agents 122, may be selected in response to numerous physiological characteristics associated with an individual 108. In some embodiments, such methods may be used with regard to one or more pharmaceutical- agents 1 12 and/or combinations of one or more pharmaceutical agents 1 12 with one or more nutraceutical agents 122.

At operation 1206, the selecting operation 230 may include selecting at least one of the one or more nutraceutical agents in response to cost associated with at least one of the one or more nutraceutical agents. In some embodiments, one or more selecting units 1 10 may select at least one of the one or more nutraceutical agents 122 in response to cost associated with at least one of the one or more nutraceutical agents 122.

In some embodiments, two or more different nutraceutical agents 122 may be administered to an individual 108 in association with the same or a similar condition associated with an individual 108. In some embodiments, it may preferable to select a first nutraceutical agent 122 having a lower associated cost over a second nutraceutical agent 122 having a higher associated cost for administration to an individual 108. In other embodiments, it may be preferable to select a first nutraceutical agent 122 having a higher associated cost over a second nutraceutical agent 122 having a lower associated cost for administration to an individual 108. In some embodiments, one or more nutraceutical agents 122 may be selected in response to cost associated with the one or more nutraceutical agents 122 and numerous additional considerations. Such additional considerations include, but are not limited to, allergic response, dosage, effectiveness, interaction with other nutraceutical agents 122 and substantially any combination thereof. In some embodiments, such methods may be used with regard to one or more pharmaceutical agents 1 12 and/or combinations of one or more pharmaceutical agents 112 with one or more nutraceutical agents 122.

At operation 1208, the selecting operation 230 may include selecting at least one of the one or more nutraceutical agents in response to compatibility of at least one of the nutraceutical agents with another of the one or more nutraceutical agents. In some embodiments, one or more selecting units 110 may select at least one of the one or more. nutraceutical agents 122 in response to compatibility of at least one of the nutraceutical agents 122 with another of the one or more nutraceutical agents 122.

In some embodiments, at least one of the nutraceutical agents 122 is selected that does not interact with another of the one or more nutraceutical agents 122. In some embodiments, at least one of the nutraceutical agents 122 is selected to act in a synergistic manner with another of the one or more nutraceutical agents 122. In some embodiments, at least one of the nutraceutical agents 122 is selected to not contraindicate at least one of the one or more nutraceutical agents 122. In some embodiments, such methods may be used with regard to one or more pharmaceutical agents 112 and/or combinations of one or more pharmaceutical agents 112 with one or more nutraceutical agents 122.

FIG. 13 illustrates alternative embodiments of the example operational flow 200 of FIG. 2. FIG. 13 illustrates example embodiments where the packaging operation 240 may include at least one additional operation. Additional operations may include an operation 1302, operation 1304, operation 1306, operation 1308 and/or operation 1310. At operation 1302, the packaging operation 240 may include packaging at least one of the one or more pharmaceutical agents with one or more pharmaceutically acceptable carriers or excipients. In some embodiments, one or more packaging units 114 may package at least one of the one or more pharmaceutical agents with one or more pharmaceutically acceptable carriers or excipients.

Pharmaceutical agents 1 12 may be packaged through use of numerous known methods, such as conventional mixing, dissolving, granulating, dragee-making, levigating, emulsifying, encapsulating, entrapping or lyophilizing processes. In some embodiments, one or more pharmaceutical agents 112 may be packaged in a manner that depends on the route that the one or more pharmaceutical agents 112 are to be administered to an individual 108.

In some embodiments, one or more pharmaceutical agents 1 12 may be packaged with one or more solid or ge] phase carriers or excipients. Examples of such carriers or excipients include, but are not limited to, croscarmellose sodium, povidone, microcrystalline cellulose, calcium carbonate, calcium phosphate, various sugars, starches, cellulose derivatives, gelatin, p^'regelatinized starch, polymers such as polyethylene glycols, lactose, lactose monohydrate, sucrose, talc, gelatin, agai", pectin, acacia, magnesium, stearate, stearic acid and substantially any combination thereof. If a solid carrier is used, the one or more pharmaceutical agents 112 may be tableted, placed in a hard gelatin capsule in powder or pellet form, packaged in the form of a troche or lozenge, and the like.

In some embodiments, one or more pharmaceutical agents 1 12 may be packaged with a liquid carrier or excipient. Examples of such liquid carriers include syrup, peanut oil, olive oil, water, physiologically compatible buffers (i.e., Hanks solution and Ringers solution), physiological saline buffer, and the like. If a liquid carrier is used, the administration form may be in the form of a syrup, emulsion, drop, soft gelatin capsule, sterile injectable solution, suspension in an ampoule or vial, non-aqueous liquid suspension, and the like.

One or more pharmaceutical agents 112 may be packaged in stable water-soluble administration forms. For example, in some embodiments, a pharmaceutically acceptable salt of one or more pharmaceutical agents 112 may be dissolved in an aqueous solution of an organic or inorganic acid, such as 0.3M solution of succinic acid or citric acid. If a soluble^' salt form is not available, a pharmaceutical agent 112 may be dissolved in a suitable cosolvent or combination of cosolvents. Examples of suitable cosolvents include, but are not limited to, alcohol, propylene glycol, polyethylene glycol 300, polysorbate 80, glycerin and the like in concentrations ranging from 0-60% of the total volume. In some embodiments, one or more pharmaceutical agents 112 may be dissolved in DMSO and diluted with water. The administration form may also be in the form of a solution of a salt form of one or more pharmaceutical agents 112 in an appropriate aqueous vehicle such as water or isotonic saline or dextrose solution.

In some embodiments, pharmaceutical agents 1 12 that are hydrophobic may be packaged through use of a cosolvent system comprising benzyl alcohol, a nonpolar surfactant, a water-miscible organic polymer, and an aqueous phase. The cosolvent system may be the VPD co-solvent system. VPD is a solution of 3 percent weight/volume benzyl alcohol, 8 percent weight/volume of the nonpolar surfactant polysorbate 80, and 65 percent weigh t/volumen polyethylene glycol 300, made up to volume in absolute ethanol. The VPD co-solvent system (VPD:5W) consists of VPD diluted 1 : 1 with a 5 percent dextrose in water solution. This co-solvent system dissolves hydrophobic pharmaceutical agents 1 12 well, and itself produces low toxicity upon systemic administration. The proportions of a co-solvent system may be varied considerably without destroying its solubility and toxicity characteristics. Furthermore, the identity of the co-solvent components may be varied: for example, other low-toxicity nonpolar surfactants may be used instead of polysorbate 80; the fraction size of polyethylene glycol may be varied; other biocompatible polymers may replace polyethylene glycol (i.e., polyvinyl pyrrolidone; and other sugars or polysaccharides may substitute for dextrose). Many other delivery systems may be used to administer hydrophobic pharmaceutical agents 1 12 as well. For example, liposomes and emulsions are well known examples of delivery vehicles or carriers for hydrophobic drugs. Certain organic solvents such as dimethysulfoxide also may be employed, although usually at the cost of greater toxicity.

Some pharmaceutical agents 112 may be packaged as salts with pharmaceutically compatible counter ions. Pharmaceutically compatible salts may be formed with many acids, including hydrochloric, sulfuric, acetic, lactic, tartaric, malic, succinic, etc. Salts of pharmaceutical agents 112 tend to be more soluble in aqueous or other protonic solvents than are the corresponding free-base forms.

Numerous carriers and excipients are known and are commercially available (i.e., The Merck Index, 13^lh Edition, An Encyclopedia of Chemicals, Drugs, and Biologicals, Merck & Co. Inc., Whitehouse Station, NJ 2001 ; Mosby's Drug Guide, Mosby, Inc., St. Louis, MO 2004; Remington: The Science and Practice of Pharmacy, 20^th Edition, Lippincott Williams & Wilkins, Philadelphia, PA 2000; Physicians' Desk Reference, 58^th Edition, Thompson, PDR, Montvale, NJ 2004; U.S. Patent Nos. 6,773,721; 7,053,107; 7,049,312 and Published U.S. Patent Application No. 20040224916; herein incorporated by reference). In some embodiments, such methods may be used with regard to one or more nutraceutical agents 122 and/or combinations of one or more pharmaceutical agents 112 with one or more nutraceutical agents 122.

At operation 1304, the packaging operation 240 may include packaging at least one of the one or more pharmaceutical agents with one or more wrappers in administration form in response to at least one of the one or more parameters specifically associated with the individual. In some embodiments, one or more packaging units 114 may package at least one of the one or more pharmaceutical agents with one or more wrappers in administration form in response to at least one of the one or more parameters specifically associated with the individual 108.

In some embodiments, one or more pharmaceutical agents 1 12 may be packaged by wrapping the one or more pharmaceutical agents 1 12 into a single administration form for administration to an individual 108. In some embodiments, the one or more pharmaceutical agents 1 12 may be preformulated prior to being wrapped in one or more wrappers. For example, one or more pharmaceutical agents 1 12 that are in prescription form may be wrapped into a single administration form. In other embodiments, the one or more pharmaceutical agents 112 may be combined together and then wrapped in one or more wrappers. In other embodiments, one or more pharmaceutical agents 1 12 may be combined together with a suitable carrier and then wrapped in one or more wrappers. Numerous materials may be used to wrap the one or more pharmaceutical agents 112. Examples of such materials include, but are not limited to, polymers that include esters of cellulose and its derivatives (cellulose acetate phthalate, hydroxypropyl methylcellulose phthalate, hydroxypropyl methylcellulose acetate succinate), polyvinyl acetate phthalate, pH-sensitive methacrylic acid-methamethacrylate copolymers, shellac, and the like. Numerous water insoluble polymers may be used that include cellulose derivatives (i.e., ethylcelkilose), polyvinyl acetate, neutral copolymers based on ethyl acrylate and methylmethacrylate, copolymers of acrylic and methacrylic acid esters with quaternary ammonium groups, and the like. In some embodiments, polymers used in forming the wrappers may be plasticized. Examples of plasticizers that may be used to plasticize the wrappers include, but are not limited to, triacetin, tributyl citrate, triethyl citrate, acetyl tri-n-butyl citrate diethyl phthalate, castor oil, dibutyl sebacate, acetylated monoglycerides, and the like and/or substantially any combination thereof. In some embodiments, the plasticizer may be present at about 3 to 30 weight percent and more typically about 10 to 25 weight percent based on the polymer to which the plasticizer is added. The type of plasticizer and its content depends on the polymer or polymers, nature of the coating system. In some embodiments, water-soluble nonionic polysaccharide derivatives may be used to wrap one or more pharmaceutical agents 112. For example, hydroxypropylmethylcellulose, hydroxypropylcellulose, and/or sodium carboxymethylcellulose may be used. Such polymers form coatings that quickly dissolve in water and have a high permeability. Accordingly, in some embodiments, such polymers may be used for rapid release of one or more pharmaceutical agents 1 12 that are wrapped in such a wrapper following administration to an individual 108. In some embodiments, one or more pharmaceutical agents 1 12 may be wrapped in a wrapper that provides for sustained release of the one or more pharmaceutical agents 112. For example, one or more pharmaceutical agents 1 12 may be released continuously over twelve hours through use of wrappers constructed from ethyl cellulose and an ethyl acrylate-methyl methacrylate-ethyl trimethylammoniumchloride methacrylate copolymer as the release controlling wrapper. Methods and materials that may be used to prepare wrappers are known in the art and are commercially available (i.e., Rohm Pharma, Piscataway, NJ; U.S. Patent Nos. 6,656,507; 7,048,945; 7,056,951; hereby incorporated by reference).

In some embodiments, one wrapper may be used to wrap one or more pharmaceutical agents 112 and/or one or more nutraceutical agents 122 into an administration form. For example, the one or more pharmaceutical agents 112 and/or one or more nutraceutical agents 122 may be combined together and then wrapped into an administration form in one wrapper for release at the same time following administration to an individual 108. In other embodiments, one continuous wrapper may be used to wrap the one or more pharmaceutical agents 1 12 and/or one or more nutraceutical agents 122 into an administration form in which the one or more pharmaceutical agents 112 and/or one or more nutraceutical agents 122 are separated from each other. For example, in some embodiments, one of the one or more pharmaceutical agents 112 may be covered with a continuous wrapper to form a core and then a second pharmaceutical agent 1 12 and/or nutraceutical agent 122 may be wrapped around the core with the continuous wrapper to produce an administration form. This process may be repeated with multiple pharmaceutical agents 1 12 and/or nutraceutical agents 122 to produce a multilayered administration form in which the multiple pharmaceutical agents 1 12 and/or the multiple nutraceutical agents 122 are separated from each other. In some embodiments, such a configuration provides for the release of pharmaceutical agents 1 12 and/or nutraceutical agents 122 from the administration form at different times and/or at different sites associated with an individual 108 to which the administration form is administered. In some embodiments, one or more pharmaceutical agents 112 are wrapped into an administration form together and additional pharmaceutical agents 1 12 and/or nutraceutical agents 122 are wrapped into the administration form in separate layers. Accordingly, pharmaceutical agents 1 12 and/or nutraceutical agents 122 may be oriented in the administration form to be released from the administration form at the same time and/or site or such that they are released at different times and/or sites. Examples of such sites include, but are not limited to, the mouth, esophagus, stomach, duodenum, small intestine, large intestine, and the rectum. In some embodiments, such methods may be used with regard to one or more nutraceutical agents 122 and/or combinations of one or more pharmaceutical agents 1 12 with one or more nutraceutical agents 122.

At operation 1306, the packaging operation 240 may include packaging at least one of the one or more pharmaceutical agents within two or more concentric wrappers in administration form in response to at least one of the one or more parameters specifically associated with the individual. In some embodiments, one or more packaging units 114 may package at least one of the one or more pharmaceutical agents within two or more concentric wrappers for administration to the individual 108.

In some embodiments, one or more packaging units 1 14 may package the one or more pharmaceutical agents 1 12 within two or more concentric wrappers for administration to the individual 108. In some embodiments, one or more pharmaceutical agents 112 may be packaged by wrapping the one or more pharmaceutical agents 112 within two or more wrappers to produce an administration form. In some embodiments, the same type of material is used to produce the two or more wrappers in the administration form. In some embodiments, different types of material are used as wrappers to produce the administration form. For example, an outer wrapper may be selected to dissolve rapidly and release one or more pharmaceutical agents 1 12 soon after administration of the administration form to the individual 108 while an inner wrapper may be selected to release one or more pharmaceutical agents 1 12 at a later time and/or at a different site associated with an individual 108. Accordingly, in some embodiments, multiple pharmaceutical agents 1 12 may be packaged into the same administration form for release at different times and at different sites following administration of the administration form to an individual 108. In some embodiments, the pharmaceutical agents 1 12 may be the same to provide for continuous dosing of an individual 108. In some embodiments, the phaπnaceutical agents 1 12 may be different to provide for dosing of an individual 108 with different pharmaceutical agents 1 12. In some embodiments, some of the pharmaceutical agents 1 12 may be the same to provide for continuous dosing of an individual 108 and others may be different to provide for dosing of an individual 108 with different pharmaceutical agents 1 12. Accordingly, numerous combinations of pharmaceutical agents 112 and wrappers may be assembled into an administration form. In some embodiments, such methods may be used with regard to one or more nutraceutical agents 122 and/or combinations of one or more phaπnaceutical agents 112 with one or more nutraceutical agents 122.

At operation 1308, the packaging operation 240 may include packaging at least one of the one or more pharmaceutical agents within two or more nested capsules and/or two or more non-nested capsules in administration form in response to at least one of the one or more parameters specifically associated with the individual. In some embodiments, one or more packaging units 114 may package at least one of the one or more pharmaceutical agents 1 12 within two or more nested capsules for administration to the individual 108.

In some embodiments, one or more phaπnaceutical agents 112 may be packaged into an administration form through use of nested capsules. In some embodiments, a first pharmaceutical agent 112 may be packaged in a first capsule and a second pharmaceutical agent 112 may be packaged in a second capsule in which the first capsule is included to create an administration form having nested capsules. Accordingly, administration forms may be constructed that include two or more nested capsules. In some embodiments, such administration forms may include two or more pharmaceutical agents 1 12. In some embodiments, such administration forms may include one or more pharmaceutical agents 112 and one or more nutraceutical agents 122. In other embodiments, such administration forms may include one type of pharmaceutical agent 112 that is contained within multiple capsules of the administration form and one or more types of different pharmaceutical agents 112 that are also contained within the capsules included within the administration form. In other embodiments, such administration forms may include one or more types of pharmaceutical agents 1 12 that are contained within multiple capsules of the administration form and one or more types of nutraceutical agents 122 that are also contained within the capsules included within the administration form. In some embodiments, the materia] used to construct the individual capsules of a single administration form is the same. In some embodiments, the material used to construct the individual capsules of a single administration form is different. In some embodiments, the material used to construct some of the individual capsules of a single administration form may be the same while the material used to construct other individual capsules of the single administration form may be different. Accordingly, through selection of materials used to construct the individual capsules contained in an administration form, one or more pharmaceutical agents 112 and/or one or more nutraceutical agents 122 may be released from one administration form at one or more times and/or at one or more sites associated with the individual 108. For example, as with wrapping materials described herein, materials may be selected for constructing capsules that release one or more pharmaceutical agents 112 and/or one or more nutraceutical agents 122 at a site associated with an individual 108. Examples of such sites include, but are not limited to, the mouth, esophagus, stomach, duodenum, small intestine, large intestine, and the rectum. In some embodiments, such methods may be used with regard to one or more nutraceutical agents 122 and/or combinations of one or more pharmaceutical agents 1 12 with one or more nutraceutical agents 122.

At operation 1310, the packaging operation 240 may include packaging at least one of the one or more pharmaceutical agents within at least one tablet in administration form in response to at least one of the one or more parameters specifically associated with the individual. In some embodiments, one or more packaging units 114 may package at least one of the one or more pharmaceutical agents 112 within at least one tablet in administration form in response to at least one of the one or more parameters 106 specifically associated with the individual 108.

In some embodiments, one or more pharmaceutical agents 1 12 may be selected in response to one or more parameters 106 associated with an individual 108 and packaged into at least one table. In some embodiments, one or more pharmaceutical agents 112 and one or more nutraceutical agents 122 may be selected in response to one or more parameters 106 associated with an individual 108 and packaged into at least one table. Methods that may be used to package one or more pharmaceutical agents 1 12 into at least one tablet for administration to an individual 108 are known (i.e., Published U.S. Patent Application Nos. 20040224916 and 20050013863; and U.S. Patent Nos. 5,490,962; 6,280,771 ; herein incorporated by reference). Such methods may be used to package one or more pharmaceutical agents 1 12 and one or more nutraceutical agents 122 into at least one tablet for administration to an individual 108. Accordingly, in some embodiments, two or more pharmaceutical agents 1 12 may be packaged into a tablet such that the two or more pharmaceutical agents 1 12 are released at the same or different times following administration of the tablet to an individual 108. In other embodiments, two or more pharmaceutical agents 1 12 may be packaged into a tablet such that the two or more pharmaceutical agents 1 12 are released at the same or different sites associated with an individual 108 following administration of the tablet to an individual 108. In other embodiments, two or more pharmaceutical agents 112 may be packaged into a tablet such that the two or more pharmaceutical agents 1 12 are released at the same or different times and at the same or different sites associated with an individual 108 following administration of the tablet to the individual 108. In some embodiments, such methods may be used with regard to one or more nutraceutical agents 122 and/or combinations of one or more pharmaceutical agents 112 with one or more nutraceutical agents 122.

FIG. 14 illustrates alternative embodiments of the example operational flow 200 of FIG. 2. FIG. 14 illustrates example embodiments where the packaging operation 240 may include at least one additional operation. Additional operations may include an operation 1402, operation 1404, operation 1406, and/or operation 1408.

At operation 1402, the packaging operation 240 may include packaging at least one of the one or more pharmaceutical agents with one or more pharmaceutically acceptable poloxamers, humectants, binders, disintegrants, fillers, diluents, lubricants, glidants, flow enhancers, compression aids, coloring agents, sweeteners, preservatives, suspensing agents, dispersing agents, film formers, coatings, flavoring agents or printing inks. In some embodiments, one or more packaging units 114 may package at least one of the one or more pharmaceutical agents with one or more pharmaceutically acceptable poloxamers, humectants, binders, disintegrants, fillers, diluents, lubricants, glidants, flow enhancers, compression aids, coloring agents, sweeteners, preservatives, suspensing agents, dispersing agents, film formers, coatings, flavoring agents or printing. inks.

At operation 1404, the packaging operation 240 may include packaging at least one of the one or more pharmaceutical agents in unit dosage form. In some embodiments, one or more packaging units 1 14 may package at least one of the one or more pharmaceutical agents 112 in unit dosage form.

The term "unit dosage form" refers to one or more amounts of one or more pharmaceutical agents 1 12 that are suitable as unitary dosages for individuals 108, such as human and non-human individuals 108, with each unit containing a predetermined quantity of at least one pharmaceutical agent 112 calculated to produce a desired effect, such as a therapeutic effect, in association with one or more suitable pharmaceutical carriers. Siich unit dosage forms may be packaged in numerous configurations that include, but are not limited to, tablets, capsules, ampoules, and other administration forms known in the art and described herein. In some embodiments, two or more unit dosage forms of one or more pharmaceutical agents 112 may be packaged into an administration form. For example, in some embodiments, two unit dosage forms may be wrapped into an administration form through use of a continuous wrapper such that they are released at different times following administration to an individual 108. In such an example, two unit dosage forms are included within one administration form. Accordingly, numerous combinations of pharmaceutical agents 112 and unit dosage forms may be included within an administration form. In some embodiments, such methods may be used with regard to one or more nutraceutical agents 122 and/or combinations of one or more pharmaceutical agents 1 12 with one or more nutraceutical agents 122.

At operation 1406, the packaging operation 240 may include packaging at least one of the one or more pharmaceutical agents in oral administration form. In some embodiments, one or more packaging units 1 14 may package at least one of the one or more pharmaceutical agents in oral administration form.

For oral administration, one or more pharmaceutical agents 112 may be packaged into an oral administration form by combining the one or more pharmaceutical agents 1 12 with pharmaceutically acceptable carriers that are well known in the art. In some embodiments, one or more pharmaceutical agents 1 12 and one or more nutraceutical agents 122 may be packaged into an oral administration form by combining the one or more pharmaceutical agents 1 12 and one or more nutraceutical agents 122 with pharmaceutically acceptable carriers that are well known in the art. Such earners allow the one or more pharmaceutical agents 1 12 to be formulated as tablets, pills, dragees, capsules, liquids, gels, syrups, slurries, suspensions and the like, for oral ingestion by an individual 108. Oral administration forms can be obtained by combining the one or more pharmaceutical agents 1 12 with a solid excipient, optionally grinding the resulting mixture, and processing the mixture of granules, after adding suitable auxiliaries, if desired, to obtain tablets or dragee cores. Suitable excipieπts are, in particular, fillers such as sugars, including lactose, sucrose, mannitol, or sorbitol; cellulose preparations such as, for example, maize starch, wheat starch, rice starch, potato stai^{^}ch, gelatin, gum tragacanth, methyl cellulose, hydroxypropylmethyl-cellulose, sodium carboxymethylcellulose, and/or polyvinylpyrrolidone. If desired, disintegrating agents may be added, such as the cross-linked polyvinyl pyrrolidone, agar, or alginic acid or a salt thereof such as sodium alginate.

Dragee cores are provided with suitable coatings. For this purpose, concentrated sugar solutions may be used, which may optionally contain gum arabic, talc, polyvinyl pyiTolidone, carbopol gel, polyethylene glycol, and/or titanium dioxide, lacquer solutions, and suitable organic solvents or solvent mixtures. Dyestuffs or pigments may be added to the tablets or dragee coatings for identification or to characterize different combinations of pharmaceutical agents 1 12.

Oral administration forms may include push-fit capsules made of gelatin, as well as soft, sealed capsules made of gelatin and a plasticizer, such as glycerol or sorbitol. The push-fit capsules can contain one or more pharmaceutical agents 1 12 in admixture with a filler such as lactose, binders such as starches, and/or lubricants such as talc or magnesium stearate and, optionally, stabilizers. In soft capsules, the pharmaceutical agents 1 12 may be dissolved or suspended in suitable liquids, such as fatty oils, liquid paraffin, or liquid polyethylene glycols. In addition, stabilizers may be added. All oral dosage forms may be prepared in dosages suitable for such administration. For buccal administration, the pharmaceutical agents 1 12 may take the form of tablets or lozenges formulated in a conventional manner. In some embodiments, such methods may be used with regard to one or more nutraceutical agents 122 and/or combinations of one or more pharmaceutical agents 1 12 with one or more nutraceutical agents 122.

At operation 1408, the packaging operation 240 may include packaging at least one of the one or more pharmaceutical agents in parenteral administration form. In some embodiments, one or more packaging units 1 14 may package at least one of the one or more pharmaceutical agents in parenteral administration form.

The one or more pharmaceutical agents 1 12 may be formulated for parenteral administration by injection (i.e., bolus injection or continuous infusion). In some embodimens, one or more pharmaceutical agents 112 and one or more nutraceutical agents 122 may be formulated for parenteral administration by injection. Formulations for injection may be presented in unit dosage form (i.e., in ampoules or in multi-dose containers) with an added preservative. The administration forms may take such forms as suspensions, solutions or emulsions in oily or aqueous vehicles, and may contain formulatory agents such as suspending, stabilizing and/or dispersing agents.

Administration forms for parenteral administration may include aqueous solutions of the one or more pharmaceutical agents 112 in water-soluble form. In some embodiments, the one or more pharmaceutical agents 112 may be formulated in physiologically compatible buffers that include Hanks solution, Ringers solution, physiological saline buffer, and the like. Additionally, suspensions of the one or more pharmaceutical agents 112 may be prepared as appropriate oily injection suspensions. Suitable lipophilic solvents include fatty oils such as sesame oil, or synthetic fatty acid esters, such as ethyl oleate or triglycerides, or liposomes. Aqueous injection suspensions may include substances which increase the viscosity of the suspension, such as sodium carboxymethyl cellulose, sorbitol, or dextran. Optionally, the suspension may also contain suitable stabilizers or agents which increase the solubility of the one or more pharmaceutical agents 112 to allow for the preparation of highly concentrated solutions. In some embodiments, such methods may be used with regard to one or more nutraceutical agents 122 and/or combinations of one or more pharmaceutical agents 112 with one or more nutraceutical agents 122. FlG. 15 illustrates alternative embodiments of the example operational flow 200 of FlG. 2. FlG. 15 illustrates example embodiments where the packaging operation 240 may include at least one additional operation. Additional operations may include an operation 1502, operation 1504, operation 1506, operation 1508 and/or operation 1510.

At operation 1502, the packaging operation 240 may include packaging at least one of the one or more pharmaceutical agents in transdermal administration form. In some embodiments, one or more packaging units 1 14 may package at least one of the one or more pharmaceutical agents 1 12 in transdermal administration form.

For transdermal, including transmucosal, administration of the one or more pharmaceutical agents 1 12, penetrants appropriate to the barrier or barriers to be permeated may be used in the formulation. Briefly, in some embodiments, a transdermal administration form may include an ethoxylated lipid, an alcohol mixed with the ethoxylated lipid to form a penetration enhancer, an aqueous adjuvant mixed with the penetration enhancer, and a delivered pharmaceutical agent 112 mixed with the aqueous adjuvant and the penetration enhancer. In some embodiments, the aqueous adjuvant is a plant extract from the family of Liliaceae Liliaceae. In some embodiments, the ethoxylated lipid is a vegetable oil or animal oil having at least 20 ethoxylations per molecule. In other embodiments, about 0.1 percent to 40.0 percent by weight or volume is ethoxylated lipid. Other embodiments may include a transdermal delivery system that includes about 0.1 percent to 15 percent by weight or volume of alcohol or where about 0.1 percent to 85 percent by weight or volume is Aloe Vera. Numerous transdermal administration forms are known and have been described (i.e., U.S. Patent Nos. 5,820,876; 7,045,145; 6,946,144; incorporated herein by reference). In some embodiments, such methods may be used with regard to one or more nutraceutical agents 122 and/or combinations of one or more pharmaceutical agents 1 12 with one or more nutraceutical agents 122.

At operation 1504, the packaging operation 240 may include packaging at least one of the one or more pharmaceutical agents in pulmonary administration form. In some embodiments, one or more packaging units 1 14 may package at least one of the one or more pharmaceutical agents 112 in pulmonary administration form. For pulmonary administration, the one or more pharmaceutical agents 112 may be delivered in the form of an aerosol spray from pressurized packs or a nebuliser, with the use of a suitable propellant (i.e., dichlorodifluoromethane, trichlorofluoromethane, dichlorotetrafluoroethane, carbon dioxide or other suitable gas). In some embodiments, one or more pharmaceutical agents 1 12 and one or more nutraceutical agents 122 may be delivered in the form of an aerosol spray from pressurized packs or a nebuliser, with the use of a suitable propellant. In the case of a pressurized aerosol, the dosage unit may be determined by providing a valve to deliver a metered amount of the one or more pharmaceutical agents 1 12. Capsules and cartridges for use in an inhaler or insufflator may be formulated to contain a powder mix of the one or more pharmaceutical agents 1 12 and a suitable powder base such as lactose or starch. Methods and materials that may be used to package one or more pharmaceutical agents 112 in pulmonary administration form are known and have been described (i.e., U.S. Patent Nos. 6,921,527; 6,838,0763; 6,565,841 ; 6,451,286; 6,169,068; 5,993,783; 5,780,014; 5,719,123; 5,354,934; 5,284,656; 5,006,343; hereby incorporated by reference). In some embodiments, such methods may be used with regard to one or more nutraceutical agents 122 and/or combinations of one or more pharmaceutical agents 1 12 with one or more nutraceutical agents 122.

At operation 1506, the packaging operation 240 may include packaging at least one of the one or more pharmaceutical agents in depot administration form. In some embodiments, one or more packaging units 1 14 may package at least one of the one or more pharmaceutical agents 112 in depot administration form.

In some embodiments, depot administration forms may be administered by implantation (i.e., subcutaneously, intramuscularly, intramuscular injection, subtenon, intravitreal injection). Accordingly, for example, the one or more pharmaceutical agents 112 may be packaged with suitable polymeric or hydrophobic materials, ion exchange resins, and the like. Methods and materials that may be used to package pharmaceutical agents 1 12 in depot administration form are known and are commercially available (i.e., U.S. Patent Nos. 6,773,714; 6,630,155; 6,565,874; 5,945,1 15; herein incorporated by reference). In some embodiments, such methods may be used with regard to one or more nutraceutical agents 122 and/or combinations of one or more pharmaceutical agents 112 with one or more nutraceutical agents 122.

At operation 1508, the packaging operation 240 may include packaging at least one of the one or more pharmaceutical agents in response to a rapid release profile. In some embodiments, one or more packaging units 1 14 may package at least one of the one or more pharmaceutical agents 1 12 in response to a rapid release profile.

In some embodiments, water-soluble nonionic polysaccharide derivatives may be used to package one or more pharmaceutical agents 1 12. For example, hydroxypropylmethylcellulose, hydroxypropylcellulose, and/or sodium carboxymethylcellulose may be used. Such polymers form coatings that quickly dissolve in water and have a high permeability. Accordingly, in some embodiments, such polymers may be used for rapid release of one or more pharmaceutical agents 112 that are packaged in such materials following administration to an individual 108. Numerous rapid release formulations are known and have been described (i.e., U.S. Patent No. 6,979,463; herein incorporated by reference). In some embodiments, such methods may be used with regard to one or more nutraceutical agents 122 and/or combinations of one or more pharmaceutical agents 112 with one or more nutraceutical agents 122.

At operation 1510, the packaging operation 240 may include packaging at least one of the one or more pharmaceutical agents in response to specified release at one or more times. In some embodiments, one or more packaging units 114 may package at least one of the one or more pharmaceutical agents 1 12 in response to specified release at one or more times.

In some embodiments, one or more pharmaceutical agents 112 may be packaged so that they are released from an administration form at one or more times following administration to an individual 108. In some embodiments, one or more pharmaceutical agents 1 12 and one or more nutraceutical agents 122 may be packaged so that they are released from an administration form at one or more times following administration to an individual 108. In some embodiments, one or more pharmaceutical agents 1 12 may be released at one or more times following administration to maintain the dosage of the one or more pharmaceutical agents 1 12 at or above a certain concentration. Accordingly, in some embodiments, the concentration of one pharmaceutical agent 112 may be maintained over a period of time in association with an individual 108. In other embodiments, the concentration of more than one pharmaceutical agent 1 12 may be maintained over a period of time in association with an individual 108. In some embodiments, one or more pharmaceutical agents 1 12 may be packaged to be released in anticipation of an event, such as a long airplane flight. For example, in some embodiments, one or more pharmaceutical agents 1 12 that induce sleep may be packaged into an administration form so that an individual 108 to whom the administration form is administered will fall asleep at a precalculated time on an airplane during a long flight. In other embodiments, one or more pharmaceuticals may be packaged into an administration form such that an individual 108 to whom the administration form is administered will not fall asleep during a long meeting or presentation. For example, an administration form may be prepared with non-drowsy versions of one or more pharmaceutical agents 1 12. Numerous methods may be used to package one or more pharmaceutical agents 112 for release at one or more times. For example, in some embodiments, one or more pharmaceutical agents 112 may be wrapped into an administration form through methods described herein. In such examples, the time of release of the one or more pharmaceutical agents 112 from the administration form may be controlled through selection of wrappers used to formulate the administration form. For example, a thick wrapper may be used to delay release while a thin wrapper may be used to expedite release of the one or more pharmaceutical agents 1 12 from the administration form. In other embodiments, one or more wrappers may be selected that are made of material that is more or less resistant to degradation when administered to an individual 108. Accordingly, materials having various chemical and physical properties may be selected to produce administration forms that release one or more pharmaceutical agents 1 12 at one or more times. In some embodiments, such methods may be used with regard to one or more nutraceutical agents 122 and/or combinations of one or more pharmaceutical agents 1 12 with one or more nutraceutical agents 122.

FIG. 16 illustrates alternative embodiments of the example operational flow 200 of FlG. 2. FIG. 16 illustrates example embodiments where the packaging operation 240 may include at least one additional operation. Additional operations may include an operation 1602, operation 1604, operation 1606, operation 1608 and/or operation 1610.

16 At operation 1602, the packaging operation 240 may include packaging at least one of the one or more pharmaceutical agents in response to release over one or more time intervals. In some embodiments, one or more packaging units 1 14 may package at least one of the one or more pharmaceutical agents 1 12 in response to release over one or more time intervals.

In some embodiments, one or more pharmaceutical agents 1 12 may be packaged so that they are released from an administration form over one or more time intervals following administration to an individual 108. In some embodiments, one or more pharmaceutical agents 1 12 and one or more nutraceutical agents 122 may be packaged so that they are released from an administration form over one or moi-e time intervals following administration to an individual 108. In some embodiments, one or more pharmaceutical agents 1 12 may be released over one or more times following administration to maintain the dosage of the one or more pharmaceutical agents 112 at or above a certain concentration. Accordingly, in some embodiments, the concentration of one pharmaceutical agent 112 may be maintained over a period of time in association with an individual 108. In other embodiments, the concentration of more than one pharmaceutical agent 1 12 may be maintained over a period of time in association with an individual 108. In some embodiments, one or more pharmaceutical agents 112 may be packaged to be released over one or more time intervals in anticipation of an event, such as a long airplane flight, that may occur during the one or more time intervals. For example, in some embodiments, one or more pharmaceutical agents 1 12 that induce sleep may be packaged into an administration form so that they are released during the time interval in which an individual 108 to whom the administration form is administered is on an airplane. Numerous methods may be used to package one or more pharmaceutical agents 1 12 for release over one or more time intervals. For example, in some embodiments, one or more pharmaceutical agents 1 12 may be wrapped into an administration form through methods described herein. In such examples, the time of release of the one or more pharmaceutical agents 1 12 from the administration form may be controlled through selection of wrappers used to prepare the administration form. For example, a thick wrapper may be used to delay release while a thin wrapper may be used to expedite release of the one or more pharmaceutical agents 1 12 from the administration form. In other embodiments, one or more wrappers may be selected that are made of materia! that is more or less resistant to degradation when administered to an individual 108. In other embodiments, controlled-release formulations may be acquired and then packaged for release over one or more time intervals. In some embodiments, such methods may be used with regard to one or more nutraceutical agents 122 and/or combinations of one or more pharmaceutical agents 1 12 with one or more nutraceutical agents 122.

At operation 1604, the packaging operation 240 may include packaging at least one of the one or more pharmaceutical agents in response to release at one or more sites specifically associated with the individual. In some embodiments, one or more packaging units 114 may package at least one of the one or more pharmaceutical agents in response to release at one or more sites specifically associated with the individual 108.

One or more pharmaceutical agents 112 may be packaged for administration to numerous sites that are associated with an individual 108. One or more pharmaceutical agents 112 and one or more nutraceutical agents 122 may be packaged for administration to numerous sites that are associated with an individual 108. Examples of such sites include, but are not limited to, the eyes, ears, nose, skin, mouth, stomach, intestine, rectum, vagina, vascular system, pulmonary system, gastrointestinal system, urinary system and lymphatic system. Accordingly, in some embodiments, release of one or more pharmaceutical agents 1 12 from an administration form at one or more sites associated with an individual 108 may be controlled through selection of materials that degrade under conditions present at the desired site of release. For example, for release in the stomach, one or more pharmaceutical agents 1 12 may be packaged into an administration form that degrades when exposed to acidic conditions. In other examples, one or more pharmaceutical agents 1 12 may be released in the gastrointestinal tract by preparing an administration form that is acid resistant but that degrades under basic conditions. Numerous methods are known that may be used to release one or more pharmaceutical agents 112 at one or more sites associated with an individual 108. In some embodiments, such methods may be used with regard to one or more nutraceutical agents 122 and/or combinations of one or more pharmaceutical agents 1 12 with one or more nutraceutical agents 122. At operation 1606, the packaging operation 240 may include packaging at least one of the one or more pharmaceutical agents in response to a sustained release profile. In some embodiments, one or more packaging units 1 14 may package at least one of the one or more pharmaceutical agents in response to a sustained release profile.

In some embodiments, one or more pharmaceutical agents 1 12 may be packaged with a carrier that may include a time-delay or time-release material known in the art, such as glyceryl monostearate or glyceryl distearate alone or with a wax, ethylcellulose, hydroxypropylmethylcellulose, methylmethaciylate and the like. Additionally, in some embodiments, one or more pharmaceutical agents 112 may be administered using a sustained-release system, such as semipermeable matrices of solid hydrophobic polymers containing the one or more pharmaceutical agents 112. Various sustained-release materials are known and have been described. For example, sustained-release capsules may, depending on their chemical composition, release one or more pharmaceutical agents 1 12 for a few weeks up to over 100 days. Numerous additional sustained-release formulations are known and have been described (i.e., U.S. Patent Nos. 7,041,670; 7,041 ,317; 6,709,676; herein incorporated by reference). In some embodiments, such methods may be used with regard to one or more nutraceutical agents 122 and/or combinations of one or more pharmaceutical agents 112 with one or more nutraceutical agents 122.

At operation 1608, the packaging operation 240 may include packaging at least one of the one or more pharmaceutical agents in storage material. In some embodiments, one or more packaging units 114 may package at least one of the one or more pharmaceutical agents 1 12 in storage material.

One or more pharmaceutical agents 1 12 may be packaged in numerous types of storage material. Examples of storage material include, but are not limited to, containers, boxes, ampoules, vials, syringes, and the like. In some embodiments, storage material includes advertising. In some embodiments, storage material includes instructions for administration. Such instructions may include time for administration, route of administration, the name of the individual 108 to whom the one or more pharmaceutical agents 112 are to be administered, the identity of the one or more pharmaceutical agents 1 12, the dosage of the one or more pharmaceutical agents 112, appropriate buffers for suspension of the one or more pharmaceutical agents 1 12, the source of the one or more pharmaceutical agents 1 12, the name of a physician or physicians who prescribed the one or more pharmaceutical agents 112, the date when the one or more pharmaceutical agents 112 were prescribed, the date when the one or more pharmaceutical agents 112 were packaged, the date when the one or more pharmaceutical agents 112 were manufactured, the expiration date of the one or more pharmaceutical agents 1 12, and the like. In some embodiments, such methods may be used with regard to one or more nutraceutical agents 122 and/or combinations of one or more pharmaceutical agents 1 12 with one or more nutraceutical agents 122.

At operation 1610, the packaging operation 240 may include labeling at least one of the one or more pharmaceutical agents. In some embodiments, one or more packaging units 1 14 may label at least one of the one or more pharmaceutical agents 112.

In some embodiments, one or more packaging units 114 may place a label directly on at least one of the one or more pharmaceutical agents 112. Numerous methods may be used to label at least one of the one or more pharmaceutical agents 112. For example, in some embodiments, one or more labeling units may stamp an indented label into at least one of the one or more pharmaceutical agents 112. In some embodiments, one or more packaging units 114 may stamp a label onto at least one of the one or more pharmaceutical agents 112 through use of one or more edible dyes. Such labels may include numerous types of information. For example, such labels may indicate the manufacturer of at least one of the one or more pharmaceutical agents 1 12, the date of manufacture, the date of packaging, the dosage, the route of administration, and the like. Such labels may be in substantially any language. In some embodiments, at least one label may be a bar code. In some embodiments, such methods may be used with regard to one or more nutraceutical agents 122 and/or combinations of one or more pharmaceutical agents 112 with one or more nutraceutical agents 122.

FIG. 17 illustrates alternative embodiments of the example operational flow 200 of FIG. 2. FIG. 17 illustrates example embodiments where the packaging operation 240 may include at least one additional operation. Additional operations may include an operation 1702, operation 1704, operation 1706, operation 1708 and/or operation 1710. At operation 1702, the packaging operation 240 may include labeling storage material containing at least one of the one or more pharmaceutical agents. In some embodiments, one or more packaging units 1 14 may label storage material containing at least one of the one or more pharmaceutical agents 1 12. .

In some embodiments, storage material may be labeled with advertising. In some embodiments, storage material may be labeled with instructions for administration. Such instructions may include time for administration, route of administration, the name of the individual 108 to whom the one or more pharmaceutical agents 1 12 are to be administered, the identity of the one or more pharmaceutical agents 112, the dosage of the one or more pharmaceutical agents 1 12, appropriate buffers for suspension of the one or more pharmaceutical agents 112, the source of the one or more pharmaceutical agents 112, the name of a physician or physicians who prescribed the one or more pharmaceutical agents 112, the date when the one or more pharmaceutical agents 112 were prescribed, the date when the one or more pharmaceutical agents 112 were packaged, the date when the one or more pharmaceutical agents 112 were manufactured, the expiration date of the one or more pharmaceutical agents 112, and the like. In some embodiments, such methods may be used with regard to one or more nutraceutical agents 122 and/or combinations of one or more pharmaceutical agents 112 with one or more nutraceutical agents 122.

At operation 1704, the packaging operation 240 may include packaging at least one of the one or more irutraceutical agents with one or more pharmaceutically acceptable carriers or excipients. In some embodiments, one or more packaging units 1 14 may package at least one of the one or more nutraceutical agents 122 with one or more pharmaceutically acceptable carriers or excipients.

Nutraceutical agents 122 may be packaged through use of numerous known methods, such as conventional mixing, dissolving, granulating, dragee-making, levigating, emulsifying, encapsulating, entrapping or lyophilizing processes. In some embodiments, the nutraceutical agents 122 may be packaged in a manner that depends on the route that the nutraceutical agents 122 are to be administered to an individual 108.

In some embodiments, one or more nutraceutical agents 122 may be packaged with one or more solid or gel phase carriers or excipients. In some embodiments, one or more nutraceutical agents 122 and one or more pharmaceutical agents 1 12 may be packaged with one or more solid or gel phase carriers or excipients. Examples of such carriers or excipients include, but are not limited to, croscarmellose sodium, povidone, microcrystalline cellulose, calcium carbonate, calcium phosphate, various sugars, starches, cellulose derivatives, gelatin, pregelatinized starch, polymers such as polyethylene glycols, lactose, lactose monohydrate, sucrose, talc, gelatin, agar, pectin, acacia, magnesium stearate, stearic acid and substantially any combination thereof. If a solid carrier is used, the one or more nutraceutical agents 122 may be tableted,^' placed in a hard gelatin capsule in powder or pellet form, packaged in the form of a troche or lozenge, and the like.

In some embodiments, one or more nutraceutical agents 122 may be packaged with a liquid earner or excipient. In some embodiments, one or more nutraceutical agents 122 and one or more pharmaceutical agents 112 may be packaged with a liquid carrier or excipient. Examples of such liquid carriers include syrup, peanut oil, olive oil, water, physiologically compatible buffers (i.e., Hanks solution and Ringers solution), physiological saline buffer, and the like. If a liquid earner is used, the administration form may be in the form of a syrup, emulsion, drop, soft gelatin capsule, sterile injectable solution, suspension in an ampoule or vial, non-aqueous liquid suspension, and the like.

One or more nutraceutical agents 122 may be packaged in stable water-soluble administration forms. In some embodiments, one or more nutraceutical agents 122 and one or more pharmaceutical agents 112 may be packaged in stable water-soluble administration forms. For example, in some embodiments, a pharmaceutically acceptable salt of one or more nutraceutical agents 122 may be dissolved in an aqueous solution of an organic or inorganic acid, such as 0.3M solution of succinic acid or citric acid. If a soluble salt form is not available, a nutraceutical agent 122 may be dissolved in a suitable cosolvent or combination of cosolvents. Examples of suitable cosolvents include, but are not limited to, alcohol, propylene glycol, polyethylene glycol 300, polysorbate 80, glycerin and the like in concentrations ranging from 0-60% of the total volume. In some embodiments, one or more nutraceutical agents 122 may be dissolved in DMSO and diluted with water. The administration form may also be in the form of a solution of a salt form of one or more nutraceutical agents 122 in an appropriate aqueous vehicle sucli as water or isotonic saline or dextrose solution.

In some embodiments, nutraceutical agents 122 that are hydrophobic may be packaged through use of a cosolvent system comprising benzyl alcohol, a nonpolar surfactant, a water-miscible organic polymer, and an aqueous phase. The cosolvent system may be the VPD co-solvent system. VPD is a solution of 3 percent weight/volume benzyl alcohol, .8 percent weight/volume of the nonpolar surfactant polysorbate 80, and 65 percent weight/volumen polyethylene glycol 300, made up to volume in absolute ethanol. The VPD co-solvent system (VPD:5W) consists of VPD diluted 1 : 1 with a 5 percent dextrose in water solution. This co-solvent system dissolves hydrophobic pharmaceutical agents well, and itself produces low toxicity upon systemic administration. Accordingly, the co-solvent system may also be used to dissolve hydrophobic nutraceutical agents 122. The proportions of a co-solvent system may be varied considerably without destroying its solubility and toxicity characteristics. Furthermore, the identity of the co-solvent components may be varied: for example, other low-toxicity nonpolar surfactants may be used instead of polysorbate 80; the fraction size of polyethylene glycol may be varied; other biocompatible polymers may replace polyethylene glycol (i.e., polyvinyl pyrrolϊdone; and other sugars or polysaccharides may substitute for dextrose). Many other delivery systems may be used to administer hydrophobic nutraceutical agents 122 as well. For example, liposomes, and emulsions are well known examples of delivery vehicles or carriers for hydrophobic drugs that may also be used to deliver nutraceuticals.- Certain organic solvents such as dimethysulfoxide also may be employed, although usually at the cost of greater toxicity.

Some nutraceutical agents 122 may be packaged as salts with compatible counter ions. Compatible salts may be formed with many acids, including hydrochloric, sulfuric, acetic, lactic, tartaric, malic, succinic, etc. Salts of nutraceutical agents 122 may be more soluble in aqueous or other protonic solvents than are the corresponding free-base forms.

Numerous carriers and excipients are known and are commercially available (i.e., The Merck Index, 13^lh Edition, An Encyclopedia of Chemicals, Drugs, and Biologicals, Merck & Co. Inc., Whitehouse Station, NJ 2001; Mosby's Drug Guide, Mosby, Inc., St. Louis, MO 2004; Remington: The Science and Practice of Pharmacy, 20^Ul Edition, Lippincott Williams & Wilkins, Philadelphia, PA 2000; Physicians' Desk Reference, 58^th Edition, Thompson, PDR, Montvale, NJ 2004; U.S. Patent Nos. 6,773,721; 7,053,107; 7,049,312 and Published U.S. Patent Application No. 20040224916; herein incorporated by reference). In some embodiments, such methods may be used with regard to one or more pharmaceutical agents 112 and/or combinations of one or more nutraceutical agents 122 with one or more pharmaceutical agents 1 12.

At operation 1706, the packaging operation 240 may include packaging at least one of the one or more nutraceutical agents with one or more wrappers in administration form in response to at least one of the one or more parameters specifically associated with the individual. In some embodiments, one or more packaging units 1 14 may package the one or more nutraceutical agents 122 with one or more wrappers in response to at least one of the one or more parameters 106 associated with the individual 108.

In some embodiments, one or more nutraceutical agents 122 may be packaged by wrapping the one or more nutraceutical agents 122 into a single administration form for administration to an individual 108. In some embodiments, one or more nutraceutical agents 122 and one or more pharmaceutical agents 112 may be packaged by wrapping the one or more nutraceutical agents 122 and one or more pharmaceutical agents 112 into a single administration form for administration to an individual 108. In some embodiments, the one or more nutraceutical agents 122 and/or one or more pharmaceutical agents 112 may be preformulated prior to being wrapped in one or more wrappers. For example, one or more nutraceutical agents- 122 that are each in tablet form may be wrapped into a single administration form. In other embodiments, one or more nutraceutical agents 122 and/or one or more pharmaceutical agents 112 may be combined together and then wrapped in one or more wrappers. In other embodiments, two or more nutraceutical agents 122 may be combined together with a suitable carrier and then wrapped in one or more wrappers. Numerous materials may be used to wrap the one or more nutraceutical agents 122. Examples of such materials include, but are not limited to, polymers that include esters of cellulose and its derivatives (cellulose acetate phthalate, hydroxypropyl methylcellulose phthalate, hydroxypropyl methylcelhilose acetate succinate), polyvinyl acetate phthalate, pH-sensitive methacrylic acid- methamethacrylate copolymers, shellac, and the like. Numerous water insoluble polymers may be used that include cellulose derivatives (i.e., ethylcellulose), polyvinyl acetate, neutral copolymers based on ethyl acrylate and methylmethacrylate, copolymers of acrylic and methacrylic acid esters with quaternary ammonium groups, and the like. In some embodiments, polymers used in forming the wrappers may be plasticized. Examples of plasricizers that may be used to plasticize the wrappers include, but are not limited to, triacetin, tributyl citrate, triethyl citrate, acetyl tri-n-butyl citrate diethyl phthalate, castor oil, dibutyl sebacate, acetylated monoglycerides, and the like and/or substantially any combination thereof. In some embodiments, the plasticizer may be present at about 3 to 30 weight percent and more typically about 10 to 25 weight percent based on the polymer to which the plasticizer is added. The type of plasticizer and its content depends on the polymer or polymers, nature of the coating system. In some embodiments, water-soluble nonionic polysaccharide derivatives may be used to wrap one or more nutraceutical agents 122. For example, hydroxypropylmethylcellulose, hydroxypropylcellulose, and/or sodium carboxymethylcellulose may be used. Such polymers form coatings that quickly dissolve in water and have a high permeability. Accordingly, in some embodiments, such polymers may be used for rapid release of one or more nutraceutical agents 122 that are wrapped in such a wrapper following administration to an individual 108. In some embodiments, one or more nutraceutical agents 122 may be wrapped in a wrapper that provides for sustained release of the one or more nutraceutical agents 122. For example, one or more nutraceutical agents 122 may be released continuously over twelve hours through use of wrappers constructed from ethyl cellulose and an ethyl acrylate-methyl methacrylate-ethyl trimethylamrnoniumchlorϊde methacrylate copolymer as the release controlling wrapper. Methods and materials that may be used to prepare wrappers are known in the art and are commercially available (i.e., Rohm Pharma, Piscataway, NJ; U.S. Patent Nos. 6,656,507; 7,048,945; 7,056,951; hereby incorporated by reference).

In some embodiments, one wrapper may be used to wrap one or more nutraceutical agents 122 into an administration form. For example, the one or more nutraceutical agents 122 may be combined together and then wrapped into an administration form in one wrapper for release at the same time following administration to an individual 108. In other embodiments, one continuous wrapper may be used to wrap the one or more nutraceutical agents 122 into an administration form in which the nutraceutical agents 122 are separated from each other. For example, in some embodiments, a first nutraceutical agent 122 may be covered with a continuous wrapper to form a core and then a second nutraceutical agent 122 may be wrapped around the core with the continuous wrapper to produce an administration form. This process may be repeated with multiple nutraceutical agents 122 to form a imtltilayered administration form in which the multiple nutraceutical agents 122 are separated from each other. In some embodiments, such a configuration provides for the release of nutraceutical agents 122 from the administration form at different times and/or at different sites associated with an individual 108 to which the administration form is administered. In some embodiments, two or more nutraceutical agents 122 are wrapped into an administration form together and additional nutraceutical agents 122 are wrapped into the administration form in separate layers. Accordingly, nutraceutical agents 122 may be oriented in the administration form to be released from the administration form at the same time and/or site or such that they are released at different times and/or sites. Examples of such sites include, but are not limited to, the mouth, esophagus, stomach, duodenum, small intestine, large intestine, and the rectum. In some embodiments, such methods may be used with regard to one or more pharmaceutical agents 112 and/or combinations of one or more nutraceutical agents 122 with one or more pharmaceutical agents 112.

At operation 1708, the packaging operation 240 may include packaging at least one of the one or more nutraceutical agents within two or more concentric wrappers in administration form in response to at least one of the one or more parameters specifically associated with the individual. In some embodiments, one or more packaging units 114 may package at least one of the one or more nutraceutical agents 122 within two or more concentric wrappers in administration form in response to at least one of the one or more parameters 106 specifically associated with the individual 108.

In some embodiments, one or more nutraceutical agents 122 may be packaged by wrapping the one or more nutraceutical agents 122 within two or more wrappers to produce an administration form. In some embodiments, the same type of material is used to produce the two or more wrappers in the administration form. In some embodiments, different types of material are used as wrappers to produce the administration form. For example, an outer wrapper may.be selected to dissolve rapidly and release one or more nutraceutical agents 122 soon after administration of the administration form to the individual 108 while an inner wrapper may be selected to release one or more nutraceutical agents 122 at a later time and/or at a different site associated with an individual 108. Accordingly, in some embodiments, multiple nutraceutical agents 122 may be packaged into the same administration form for release at different times and at different sites following administration of the administration form to an individual 108. ^■ In some embodiments, one or more nutraceutical agents 122 and one or more pharmaceutical agents 1 12 may be packaged into the same administration form for release at different times and at different sites following administration of the administration form to an individual 108. In some embodiments, the nutraceutical agents 122 and/Or pharmaceutical agents 112 may be the same to provide for continuous dosing of an individual 108. In some embodiments, the nutraceutical agents 122 and/or pharmaceutical agents 112 may be different to provide for dosing of an individual 108 with different nutraceutical agents 122 and/or pharmaceutical agents 112. In some embodiments, some of the nutraceutical agents 122 may be the same to provide for continuous dosing of an individual 108 and others may be different to provide for dosing of an individual 108 with different nutraceutical agents 122. Accordingly, numerous combinations of nutraceutical agents 122 and wrappers may be assembled into an administration form. In some embodiments, such methods may be used with regard to one or more pharmaceutical agents 1 12 and/or combinations of one or more nutraceutical agents 122 with one or more pharmaceutical agents 112.

At operation 1710, the packaging operation 240 may include packaging at least one of the one or more nutraceutical agents within two or more nested capsules and/or two or more non-nested capsules in administration form in response to at least one of the one or more parameters specifically associated with the individual. In some embodiments, one or more packaging units 1 14 may package at least one of the one or more nutraceutical agents 122 within two or more nested capsules and/or two or more non-nested capsules in administration form in response to at least one of the one or more parameters specifically associated with the individual 108. In some embodiments, one or more nutraceutical agents 122 may be packaged into an administration form through use of nested capsules. In some embodiments, one or more nutraceutical agents 122 and one or more pharmaceutical agents 112 may be packaged into an administration form through use of nested capsules. In some embodiments, a first nutraceutical agent 122 may be packaged in a first capsule and a second nutraceutical agent 122 may be packaged in a second capsule in which the first capsule is included to create an administration form having nested capsules. Accordingly, administration forms may be constructed that include two or more nested capsules. In some embodiments, such administration forms may include two or more nutraceutical agents 122. In other embodiments, such administration forms may include one type of nutraceutical agent 122 that is contained within multiple capsules of the administration form and one or more types of different nutraceutical agents 122 that are also contained within the capsules included within the administration form. In some embodiments, the material used to construct the individual capsules of a single administration form is the same. In some embodiments, the material used to construct the individual capsules of a single administration form is different. In some embodiments, the material used to construct some of the individual capsules of a single administration form may be the same while the material used to construct other individual capsules of the single administration form may be different. Accordingly, through selection of materials used to construct the individual capsules contained in an administration form, one or more nutraceutical agents 122 may be released from one administration form at one or more times and/or at one or more sites associated with the individual 108. For example, as with wrapping materials described herein, materials may be selected for constructing capsules that release one or more nutraceutical agents 122 at a site associated with an individual 108. Examples of such sites include, but are not limited to, the mouth, esophagus, stomach, duodenum, small intestine, large intestine, and the rectum. In some embodiments, such methods may be used with regard to one or more pharmaceutical agents 1 12 and/or combinations of one or more nutraceutical agents 122 with one or more pharmaceutical agents 1 12.

FIG. 18 illustrates alternative embodiments of the example operational flow 200 of FIG. 2. FIG. 18 illustrates example embodiments where the packaging operation 240 may include at least one additional operation. Additional operations may include an operation 1802, operation 1804, operation 1806, and/or operation 1808.

At operation 1802, the packaging operation 240 may include packaging at least one of the one or more nutraceutical agents within at least one tablet in administration form in response to at least one of the one or more parameters specifically associated with the individual. In some embodiments, one or more packaging units 114 may package at least one of the one or more nutraceutical agents 122 within at least one tablet in administration form in response to at least one of the one or more parameters 106 specifically associated with the individual 108.

In some embodiments, one or more nutraceutical agents 122 may be selected in response to one or more parameters 106 associated with an individual 108 and packaged into at least one table. Accordingly, in some embodiments, two or more nutraceutical agents 122 may be packaged into a tablet such that the two or more nutraceutical agents 122 are released at the same or different times following administration of the tablet to an individual 108. In other embodiments, two or more nutraceutical agents 122 may be packaged into a tablet such that the two or more nutraceutical agents 122 are released at the same or different sites associated with an individual 108 following administration of the tablet to an individual 108. In other embodiments, two or more nutraceutical agents 122 may be packaged into a tablet such that the two or more nutraceutical agents 122 are released at the same or different times and at the same or different sites associated with an individual 108 following administration of the tablet to the individual 108. In some embodiments, such methods may be used with regard to one or more pharmaceutical agents 1 12 and/or combinations of one or more nutraceutical agents 122 with one or more pharmaceutical agents 112.

At operation 1804, the packaging operation 240 may include packaging at least one of the one or more nutraceutical agents with one or more pharmaceutically acceptable poloxamers, humectants, binders, disintegrants, fillers, diluents, lubricants, glidants, flow enhancers, compression aids, coloring agents, sweeteners, preservatives, suspensing agents, dispersing agents, film formers, coatings, flavoring agents or printing inks. In some embodiments, one or more packaging units 114 may package at least one of the one or more nutraceutical agents with one or more pharmaceutically acceptable poloxamers, humectants, binders, disintegraπts, fillers, diluents, lubricants, glidants, flow enhancers, compression aids, coloring agents, sweeteners, preservatives, suspensing agents, dispersing agents, film formers, coatings, flavoring agents or printing inks. In some embodiments, such methods may be used with regard to one or more pharmaceutical agents 112 and/or combinations of one or more nutraceutical agents 122 with one or more pharmaceutical agents 1 12.

At operation 1806, the packaging operation 240 may include packaging at least one of the one or more nutraceutical agents in unit dosage form. In some embodiments, one or more packaging units 1 14 may package at least one of the one or more nutraceutical agents 122 in unit dosage form.

The term "unit dosage form" refers to one or more amounts of one or more nutraceutical agents 122 that are suitable as unitary dosages for individuals, such as human and non-human individuals, with each unit containing a predetermined quantity of at least one nutraceutical agent 122 calculated to produce a desired effect, such as a therapeutic effect, in association with one or more suitable pharmaceutical carriers. Such unit dosage forms may be packaged in numerous configurations that include, but are not limited to, tablets, capsules, ampoules, and other administration forms known in the art and described herein. In some embodiments, two or more unit dosage forms of one or more nutraceutical agents 122 may be packaged into an administration form. For example, in some embodiments, two unit dosage forms may be wrapped into an administration form through use of a continuous wrapper such that they are released at different times following administration to an individual 108. In such an example, two unit dosage forms are included within one administration form. Accordingly, numerous combinations of nutraceutical agents 122 and unit dosage forms may be included within an administration form. In some embodiments, such methods may be used with regard to one or more pharmaceutical agents 112 and/or combinations of one or more nutraceutical agents 122 with one or more pharmaceutical agents 1 12.

At operation 1808, the packaging operation 240 may include packaging at least one of the one or more nutraceutical agents in oral administration form. In some embodiments, one or more packaging units 114 may package at least one of the one or more nutraceutical agents 122 in oral administration form. For oral administration, one or more nutraceutical agents 122 may be packaged into an oral administration form by combining the one or more nutraceutical agents 122 with pharmaceutically acceptable carriers that are well known in the art. In some embodiments, one or more nutraceutical agents 122 and one or more pharmaceutical agents 1 12 may be packaged into an oral administration form by combining the one or more nutraceutical agents 122 and one or more pharmaceutical agents 1 12 with pharmaceutically acceptable carriers. Such earners allow the one or more nutraceutical agents 122 to be formulated as tablets, pills, dragees, capsules, liquids, gels, syrups, slurries, suspensions and the like, for oral ingestion by an individual 108. Oral administration forms can be obtained by combining the one or more nutraceutical agents 122 with a solid excipient, optionally grinding the resulting mixture, and processing the mixture of granules, after adding suitable auxiliaries, if desired, to obtain tablets or dragee cores. Suitable excipients are, in particular, fillers such as sugars, including lactose, sucrose, mannitol, or sorbitol; cellulose preparations such as, for example, maize starch, wheat starch, rice starch, potato starch, gelatin, gum tragacanth, methyl cellulose, hydroxypropylmethyl-cellulose, sodium carboxymethylcellulose, and/or polyvinylpyrrolidone. If desired, disintegrating agents may be added, such as the cross- linked polyvinyl pyrrolidone, agar, or alginic acid or a salt thereof such as sodium alginate.

Dragee cores are provided with suitable coatings. For this purpose, concentrated sugar solutions may be used, which may optionally contain gum arabic, talc, polyvinyl pyiTolidone, carbopol gel, polyethylene glycol, and/or titanium dioxide, lacquer solutions, and suitable organic solvents or solvent mixtures. Dyestuffs or pigments may be added to the tablets or dragee coatings for identification or to characterize different combinations of nutraceutical agents 122.

Oral administration forms may include push-fit capsules made of gelatin, as well as soft, sealed capsules made of gelatin and a plasticizer, such as glycerol or sorbitol. The push-fit capsules can contain one or more nutraceutical agents 122 in admixture with a filler such as lactose, binders such as starches, and/or lubricants such as talc or magnesium stearate and, optionally, stabilizers. In soft capsules, the nutraceutical agents 122 may be dissolved or suspended in suitable liquids, such as fatty oils, liquid paraffin, or liquid polyethylene glycols. In addition, stabilizers may be added. All oral dosage forms may be prepared in dosages suitable for such administration. For buccal administration, the nutraceutical agents 122 may take the form of tablets or lozenges formulated in a conventional manner. In some embodiments, such methods may be used with regard to one or more pharmaceutical agents 1 12 and/or combinations of one or more nutraceutical agents 122 with one or more pharmaceutical agents 112.

FIG. 19 illustrates alternative embodiments of the example operational flow 200 of FIG. 2. FIG. 19 illustrates example embodiments where the packaging operation 240 may include at least one additional operation. Additional operations may include an operation 1902, operation 1904, operation 1906, operation 1908 and/or operation 1910. At operation 1902, the packaging operation 240 may include packaging at least one of the one or more nutraceutical agents in parenteral administration form. In some embodiments, one or more packaging units 1 14 may package the one or more nutraceutical agents 122 in parenteral administration form.

The one or more nutraceutical agents 122 may be formulated for parenteral administration by injection (i.e., bolus injection or continuous infusion). In some embodiments, one or more nutraceutical agents 122 and one or more pharmaceutical agents 112 may be formulated for parenteral administration by injection. Formulations for injection may be presented in unit dosage form (i.e., in ampoules or in multi-dose containers) with an added preservative. The administration forms may take such forms as suspensions, solutions or emulsions in oily or aqueous vehicles, and may contain formulatory agents such as suspending, stabilizing and/or dispersing agents.

Administration forms for parenteral administration may include aqueous solutions of the one or more nutraceutical agents 122 in water-soluble form. In some embodiments, the one or more nutraceutical agents 122 may be formulated in physiologically compatible buffers that include Hanks solution, Ringers solution, physiological saline buffer, and the like. Additionally, suspensions of the one or more nutraceutical agents 122 may be prepared as appropriate oily injection suspensions. Suitable lipophilic solvents include fatty oils such as sesame oil, or synthetic fatty acid esters, such as ethyl oleate or triglycerides, or liposomes. Aqueous injection suspensions may include substances which increase the viscosity of the suspension, such as sodium carboxymethyl cellulose, sorbitol, or.dextran. Optionally, the suspension may also contain suitable stabilizers or agents which increase the solubility of the one or more nutraceutical agents 122 to allow for the preparation of highly concentrated solutions. In some embodiments, such methods may be used with regard to one or more pharmaceutical agents 1 12 and/or combinations of one or more nutraceutical agents 122 with one or more pharmaceutical agents 1 12,

At operation 1904, the packaging operation 240 may include packaging at least one of the one or more nutraceutical agents in transdermal administration form. In some embodiments, one or more packaging units 1 14 may package the one or more nutraceutical agents 122 in transdermal administration form.

For transdermal, including transmucosal, administration of the one or more nutraceutical agents 122, penetrants appropriate to the barrier or barriers to be permeated may be used in the formulation. Briefly, in some embodiments, a transdermal administration form may include an ethoxylated lipid, an alcohol mixed with the ethoxylated lipid to form a penetration enhancer, an aqueous adjuvant mixed with the penetration enhancer, and a delivered nutraceutical agent 122 mixed with the aqueous adjuvant and the penetration enhancer. In some embodiments, the aqueous adjuvant is a plant extract from the family of Liliaceae Liliaceae. In some embodiments, the ethoxylated lipid is a vegetable oil or animal oil having at least 20 ethoxylations per molecule. In other embodiments, about 0.1 percent to 40.0 percent by weight or volume is ethoxylated lipid. Other embodiments may include a transdermal delivery system that includes about 0.1 percent to 15 percent by weight or volume of alcohol or where about 0.1 percent to 85 percent by weight or volume is Aloe Vera. Numerous transdermal administration forms are known and have been described (i.e., U.S. Patent Nos. 5,820,876; 7,045,145; 6,946,144; incorporated herein by reference). In some embodiments, such methods may be used with regard to one or more pharmaceutical agents 1 12 and/or combinations of one or more nutraceutical agents 122 with one or more pharmaceutical agents 112.

At operation 1906, the packaging operation 240 may include packaging at least one of the one or more nutraceutical agents in pulmonary administration form. In some embodiments, one or more packaging units 114 may package the one or more nutraceutical agents 122 in pulmonary administration form.

For pulmonary administration, the one or more nutraceutical agents 122 may be delivered in the form of an aerosol spray from pressurized packs or a nebuliser, with the use of a suitable propellant (i.e., dichlorodifluoromethane, trichlorofluoromethane, dichlorotetrafluoroethane, carbon dioxide or other suitable gas). In some embodiments, one or more nutraceutical agents 122 and one or more pharmaceutical agents 1 12 may be delivered in the form of an aerosol spray from pressurized packs or a nebuliser, with the use of a suitable propellant. In the case of a pressurized aerosol, the dosage unit may be determined by providing a valve to deliver a metered amount of the one or more nutraceutical agents 122. Capsules and cartridges for use in an inhaler or insufflator may be formulated to contain a powder mix of the one or more nutraceutical agents 122 and a suitable powder base such as lactose or starch. Methods and materials that may be used to package one or more nutraceutical agents 122 in pulmonary administration form are known and have been described (i.e., U.S. Patent Nos. 6,921,527; 6,838,076; 6,565,841; 6,451 ,286; 6,169,068; 5,993,783; 5,780,014; 5,719,123; 5,354,934; 5,284,656; 5,006,343; hereby incorporated by reference). In some embodiments, such methods may be used with regard to one or more pharmaceutical agents 112 and/or combinations of one or more nutraceutical agents 122 with one or more pharmaceutical agents 1 12.

At operation 1908, the packaging operation 240 may include packaging at least one of the one or more nutraceutical agents in depot administration form. In some embodiments, one or more packaging units 1 14 may package the one or more nutraceutical agents 122 in depot administration form.

In some embodiments, depot administration forms may be administered by implantation (i.e., subcutaneously, intramuscularly, intramuscular injection, subtenon, intravitreal injection). Accordingly, for example, the one or more nutraceutical agents 122 may be packaged with suitable polymeric or hydrophobic materials, ion exchange resins, and the like. Methods and materials that may be used to package nutraceutical agents 122 in depot administration form are known and are commercially available (i.e., U.S. Patent Nos. 6,773,714; 6,630,155; 6,565,874; 5,945,115; herein incorporated by reference). In some embodiments, such methods may be used with regard to one or more pharmaceutical agents 1 12 and/or combinations of one or more nutraceutical agents 122 with one or more pharmaceutical agents 1 12.

At operation 1910, the packaging operation 240 may include packaging at least one of the one or more nutraceutical agents in response to a rapid release profile. In some embodiments, one or more packaging units 1 14 may package at least one of the one or more nutraceutical agents 122 in response to a rapid release profile.

In some embodiments, water-soluble nonionic polysaccharide derivatives may be used to package one or more nutraceutical agents 122. For example, hydroxypropylmethylcellulose, hydroxypropylcellulose, and/or sodium carboxymethylcellulose may be used. Such polymers form coatings that quickly dissolve in water and have a high permeability. Accordingly, in some embodiments, such polymers may be used for rapid release of one or more nutraceutical agents 122 that are packaged in such materials following administration to an individual 108. Numerous rapid release formulations are known and have been described (i.e., U.S. Patent No. 6,979,463; herein incorporated by reference). In some embodiments, such methods may be used with regard to one or more pharmaceutical agents 112 and/or combinations of one or more nutraceutical agents 122 with one or more pharmaceutical agents 1 12.

FIG. 20 illustrates alternative embodiments of the example operational flow 200 of FIG. 2. FIG. 20 illustrates example embodiments where the packaging operation 240 may include at least one additional operation. Additional operations may include an operation 2002, operation 2004, operation 2006, operation 2008 and/or operation 2010.

At operation 2002, the packaging operation 240 may include packaging at least one of the one or more nutraceutical agents in response to specified release at one or more times. In some embodiments, one or more packaging units 1 14 may package at least one of the one or more nutraceutical agents 122 in response to specified release at one or more times.

In some embodiments, one or more nutraceutical agents 122 may be packaged so that they are released from an administration form at one or more times following administration to an individual 108. In some embodiments, one or more nutraceutical agents 122 and one or more pharmaceutical agents 1 12 may be packaged so that they are released from an administration form at one or more times following administration to an individual 108. In some embodiments, one or more nutraceutical agents 122 may be released at one or more times following administration to maintain the dosage of the one or more nutraceutical agents 122 at or above a certain concentration. Accordingly, in some embodiments, the concentration of one nutraceutical agent 122 may be maintained over a period of time in association with an individual 108. In other embodiments, the concentration of more than one nutraceutical agent 122 may be maintained over a period of time in association with an individual 108. In some embodiments, one or more nutraceutical agents 122 may be packaged to be released in anticipation of an event, such as a long airplane flight. For example, in some embodiments, one or more nutraceutical agents 122 that induce sleep may be packaged into an administration form so that an individual 108 to whom the administration form is administered will fall asleep at a precalculated time on an airplane during a long flight. In other embodiments, one or more nutraceuticals may be packaged into an administration form such that an individual 108 to whom the administration form is administered will not fall asleep during a long meeting or presentation. Numerous methods may be used to package one or more nutraceutical agents 122 for release at one or more times. For example, in some embodiments, one or more nutraceutical agents 122 may be wrapped into an administration form through methods described herein. In such examples, the time of release of the one or more nutraceutical agents 122 from the administration form may be controlled through selection of wrappers used to formulate the administration form. For example, a thick wrapper may be used to delay release while a thin wrapper may be used to expedite release of the one or more nutraeeutical agents 122 from the administration form. In other embodiments, one or more wrappers may be selected that are made of material that is more or less resistant to degradation when administered to an individual 108. Accordingly, materials having various chemical and physical properties may be selected to produce administration forms that release one or more nutraceutical agents 122 at one or more times. In some embodiments, such methods may be used with regard to one or more pharmaceutical agents 112 and/or combinations of one or more nutraceutical agents 122 with one or more pharmaceutical agents 1 12.

At operation 2004, the packaging operation 240 may include packaging at least one of the one or more nutraceutical agents in response to release over one or more time intervals. In some embodiments, one or more packaging units 1 14 may package at least one of the one or more nutraceutical agents 122 in response to release over one or more time intervals.

In some embodiments, one or more nutraceutical agents 122 may be packaged so that they are released from an administration form over one or more time intervals following administration to an individual 108. In some embodiments, one or more nutraceutical agents 122 and one or more pharmaceutical agents 112 may be packaged so that they are released from an administration form over one or more time intervals following administration to an individual 108. In some embodiments, one or more nutraceutical agents 122 may be released over one or more times following administration to maintain the dosage of the one or more nutraceutical agents 122 at or above a certain concentration. Accordingly, in some embodiments, the concentration of one nutraceutical agent 122 may be maintained over a period of time in association with an individual 108. In other embodiments, the concentration of more than one nutraceutical agent 122 may be maintained over a period of time in association with an individual 108. In some embodiments, one or more nutraceutical agents 122 may be packaged to be released over one or more time intervals in anticipation of an event, such as a long airplane flight, that may occur during the one or more time intervals. For example, in some embodiments, one or more nutraceutical agents 122 that induce sleep may be packaged into an administration form so that they are released during the time interval in which an individual 108 to whom the administration form is administered is on an airplane. Numerous methods may be used to package one or more nutraceutical agents 122 for release over one or more time intervals. For example, in some embodiments, one or more nutraceutical agents 122 may be wrapped into an administration form through methods described herein. In such examples, the time of release of the one or more nutraceutical agents 122 from the administration form may be controlled through selection of wrappers used to prepare the administration form. For example, a thick wrapper may be used to delay release while a thin wrapper may be used to expedite release of the one or more nutraceutical agents 122 from the administration form. In other embodiments, one or more wrappers may be selected that are made of material that is more or less resistant to degradation when administered to an individual 108. In other embodiments, controlled-release formulations may be acquired and then packaged for release over one or more time intervals. In some embodiments, such methods may be used with regard to one or more pharmaceutical agents 112 and/or combinations of one or more nutraceutical agents 122 with one or more pharmaceutical agents 1 12.

At operation 2006, the packaging operation 240 may include packaging at least one of the one or more nutraceutical agents in response to release at one or more sites specifically associated with the individual. In some embodiments, one or more packaging units 114 may package at least one of the one or more nutraceutical agents 122 in response to release at one or more sites specifically associated with the individual 108.

One or more nutraceutical agents 122 may be packaged for administration to numerous sites that are associated with an individual 108. Examples of such sites include, but are not limited to, the eyes, ears, nose, skin, mouth, stomach, intestine, rectum, vagina, vascular system, pulmonary system, gastrointestinal system, urinary system and lymphatic system. Accordingly, in some embodiments, release of one or more nutraceutical agents 122 from an administration form at one or more sites associated with an individual 108 may be controlled through selection of materials that degrade under conditions present at the desired site of release. For example, for release in the stomach, one or more nutraceutical agents 122 may be packaged into an administration form that degrades when exposed to acidic conditions. In other examples, one or more nutraceutical agents 122 may be released in the gastrointestinal tract by preparing an administration form that is acid resistant but that degrades under basic conditions. Numerous methods are known that may be used to release one or more nutraceutical agents 122 at one or more sites associated with an individual 108. In some embodiments, such methods may be used with regard to one or more pharmaceutical agents 1 12 and/or combinations of one or more nutraceutical agents 122 with one or more pharmaceutical agents 1 12.

At operation 2008, the packaging operation 240 may include packaging at least one of the one or more nutraceutical agents in response to a sustained release profile. In some embodiments, one or more packaging units 114 may package at least one of the one or more nutraceutical agents 122 in response to a sustained release profile. In some embodiments, one or more nutraceutical agents 122 may be packaged with a carrier that may include a time-delay or time-release materia] known in the art, such as glyceryl monostearate or glyceryl distearate alone or with a wax, ethylcellulose, hydroxypropylmethylcellulose, rπethylmethacrylate and the like. Additionally, in some embodiments, one or more nutraceutical agents 122 may be administered using a sustained-release system, such as semipermeable matrices of solid hydrophobic polymers containing the one or more nutraceutical agents 122. Various sustained-release materials are known and have been described. For example, sustained-release capsules may, depending on their chemical composition, release one or more nutraceutical agents 122 for a few weeks up to over 100 days. Numerous additional sustained-release formulations are known and have been described (i.e., U.S. Patent Nos. 7,041,670; 7,041,317; 6,709,676; herein incorporated by reference). In some embodiments, such methods may be used with regard to one or more pharmaceutical agents 112 and/ or combinations of one or more nutraceutical agents 122 with one or more pharmaceutical agents 112.

At operation 2010, the packaging operation 240 may include packaging at least one of the one or more nutraceutical agents in storage material. In some embodiments, one or more packaging units 1 14 may package the one or more nutraceutical agents 122 in storage material.

One or more nutraceutical agents 122 may be packaged in numerous types of storage material. Examples of storage material include, but are not limited to, containers, boxes, ampoules, vials, syringes, and the like. In some embodiments, storage material includes advertising. In some embodiments, storage material includes instructions for administration. Such instructions may include time for administration, route of administration, the name of the individual 108 to whom the one or more nutraceutical agents 122 are to be administered, the identity of the one or more nutraceutical agents 122, the dosage of the one or more nutraceutical agents 122, appropriate buffers for suspension of the one or more nutraceutical agents 122, the source of the one or more nutraceutical agents 122, the date when the one or more nutraceutical agents 122 were packaged, the date when the one or more nutraceutical agents 122 were manufactured, the expiration date of the one or more nutraceutical agents 122, and the like. In some embodiments, such methods may be used with regard to one or more pharmaceutical agents 1 12 and/or combinations of one or more nutraceutical agents 122 with one or more pharmaceutical agents 1 12.

FJG. 21 illustrates alternative embodiments of the example operational flow 200 of FlG. 2. FJG. 21 illustrates example embodiments where the packaging operation 240 may include at least one additional operation. Additional operations may include an operation 2102, operation 2104, operation 2106, operation 2108 and/or operation 2110.

At operation 2102, the packaging operation 240 may include labeling at least one of the one or more nutraceutical agents. In some embodiments, one or more packaging units 1 14 may label at least one of the one or more nutraceutical agents 122.

In some embodiments, one or more packaging units 1 14 may place a label directly on at least one of the one or more nutraceutical agents 122. Numerous methods may be used to label at least one of the one or more nutraceutical agents 122. For example, in some embodiments, one or more labeling units may stamp an indented label into at least one of the one or more nutraceutical agents 122. In some embodiments, one or more packaging units 1 14 may stamp a label onto at least one of the one or more nutraceutical agents 122 through use of one or more edible dyes. Such labels may include numerous types of information. For example, such labels may indicate the manufacturer of at least one of the one or more nutraceutical agents 122, the date of manufacture, the date of packaging, the dosage, the route of administration, and the like. Such labels may be in substantially any language. In some embodiments, at least one label may be a bar code. In some embodiments, such methods may be used with regard to one or more pharmaceutical agents 112 and/or combinations of one or more nutraceutical agents 122 with one or more pharmaceutical agents 112.

At operation 2104, the packaging operation 240 may include labeling storage material containing at least one of the one or more nutraceutical agents. In some embodiments, one or more packaging units 1 14 may label storage material containing at least one of the one or more nutraceutical agents 122.

In some embodiments, storage material may be labeled with advertising. In some embodiments, storage material may be labeled with instructions for administration. Such instructions may include time for administration, route of administration, the name of the

300 individual 108 to whom the one or more nutraceutical agents 122 are to be administered, the identity of the one or more nutraceutical agents 122, the dosage of the one or more nutraceutical agents 122, appropriate buffers for suspension of the one or more nutraceutical agents 122, the source of the one or more nutraceutical agents 122, the date when the one or more nutraceutical agents 122 were packaged, the date when the one or more nutraceutical agents 122 were manufactured, the expiration date of the one or more nutraceutical agents 122, and the like. In some embodiments, such methods may be used with regard to one or more pharmaceutical agents 1 12 and/or combinations of one or more nutraceurical agents 122 with one or more pharmaceutical agents 1 12.

At operation 2106, the packaging operation 240 may include packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents with one or more pharmaceutically acceptable carriers or excipients. In some embodiments, one or more packaging units 114 may package at least one of the one or more pharmaceutical agents 1 12 and at least one of the one or more nutraceutical agents 122 with one or more pharmaceutically acceptable earners or excipients.

Pharmaceutical agents 112 and nutraceutical agents 122 may be packaged through use of numerous known methods, such as conventional mixing, dissolving, granulating, dragee-making, levigating, emulsifying, encapsulating, entrapping or lyophilizing processes. In some embodiments, pharmaceutical agents 112 and nutraceutical agents 122 may be packaged in a manner that depends on the route that the pharmaceutical agents 1 12 and/or and nutraceutical agents 122 are to be administered to an individual 108.

In some embodiments, one or more pharmaceutical agents 112 and one or more nutraceutical agents 122 may be packaged with one or more solid or gel phase carriers or excipients. Examples of such carriers or excipients include, but are not limited to, croscarmellose sodium, povidone, raicrocrystalline cellulose, calcium carbonate, calcium phosphate, various sugars, starches, cellulose derivatives, gelatin, pregelatinized starch, polymers such as polyethylene glycols, lactose, lactose monohydrate, sucrose, talc, gelatin, agar, pectin, acacia, magnesium stearate, stearic acid and substantially any combination thereof. If a solid carrier is used, the one or more pharmaceutical agents 112 and one or more nutraceutical agents 122 may be tableted, placed in a hard gelatin capsule in powder or pellet form, packaged in the form of a troche or lozenge, and the like.

In some embodiments, one or more pharmaceutical agents 112 and one or more nutraceutical agents 122 may be packaged with a liquid carrier or excipient. Examples of such liquid earners include syrup, peanut oil, olive oil, water, physiologically compatible buffers (i.e., Hanks solution and Ringers solution), physiological saline buffer, and the like. If a liquid carrier is used, the administration form may be in the form of a syrup, emulsion, drop, soft gelatin capsule, sterile injectable solution, suspension in an ampoule or vial, non-aqueous liquid suspension, and the like.

One or more pharmaceutical agents 1 12 and one or more nutraceutical agents 122 may be packaged in stable water-soluble administration forms. For example, in some embodiments, a pharmaceutically acceptable salt of one or more pharmaceutical agents 112 and/or one or more nutraceutical agents 122 may be dissolved in an aqueous solution of an organic or inorganic acid, such as 0.3M solution of succinic acid or citric acid. If a soluble salt form is not available, one or more pharmaceutical agents 112 and/or one or more nutraceutical agents 122 may be dissolved in a suitable cosolvent or combination of cosolvents. Examples of suitable cosolvents include, but are not limited to, alcohol, propylene glycol, polyethylene glycol 300, polysorbate 80, glycerin and the like in concentrations ranging from 0-60% of the total volume. In some embodiments, one or more pharmaceutical agents 1 12 and one or more nutraceutical agents 122 may be dissolved in DMSO and diluted with water. The administration form may also be in the form of a solution of a salt form of one or more pharmaceutical agents 1 12 in an appropriate aqueous vehicle such as water or isotonic saline or dextrose solution.

In some embodiments, pharmaceutical agents 112 and nutraceutical agents 122 that are hydrophobic may be packaged through use of a cosolvent system comprising benzyl alcohol, a nonpolar surfactant, a water-miscible organic polymer, and an aqueous phase. The cosolvent system may be the VPD co-solvent system. VPD is a solution of 3 percent weight/volume benzyl alcohol, 8 percent weight/volume of the nonpolar surfactant polysorbate 80, and 65 percent weight/volumen polyethylene glycol 300, made up to volume in absolute ethanol. The VPD co-solvent system (VPD:5W) consists of VPD diluted 1 : 1 with a 5 percent dextrose in water solution. This co-solvent system - dissolves hydrophobic pharmaceutical agents 1 12 well, and itself produces low toxicity upon systemic administration. Accordingly, such a co-solvent system may also be used to dissolve hydrophobic nutraceutical agents 122. The proportions of a co-solvent system may be varied considerably without destroying its solubility and toxicity characteristics. Furthermore, the identity of the co-solvent components may be varied: for example, other low-toxicity πonpolar surfactants may be used instead of polysorbate 80; the fraction size of polyethylene glycol may be varied; other biocompatible polymers may replace polyethylene glycol (i.e., polyvinyl pyrrolidone; and other sugars or polysaccharides may substitute for dextrose). Many other delivery systems may be used to administer hydrophobic pharmaceutical agents 1 12 and nutraceutical agents 122 as well. For example, liposomes and emulsions are well known examples of delivery vehicles or carriers for hydrophobic drugs. Certain organic solvents such as dimethysulfoxide also may be employed, although usually at the cost of greater toxicity.

Some pharmaceutical agents 1 12 and nutraceutical agents 122 may be packaged as salts with pharmaceutically compatible counter ions. Pharmaceutically compatible salts may be formed with many acids, including hydrochloric, sulfuric, acetic, lactic, tartaric, malic, succinic, etc. Salts of pharmaceutical agents 112 tend to be more soluble in aqueous or other protonic solvents than are the corresponding free-base forms. Accordingly, salts of nutraceutical agents 122 may be more soluble in aqueous or other protonic solvents than are the corresponding free-base forms as well. Numerous carriers and excipients are known and are commercially available (i.e., The Merck Index, 13^th Edition, An Encyclopedia of Chemicals, Drugs, and Biologicals, Merck & Co. Inc., Whitehouse Station, NJ 2001 ; Mosby's Drug Guide, Mosby, Inc., St. Louis, MO 2004; Remington: The Science and Practice of Pharmacy, 20^th Edition, Lippincott Williams & Wilkins, Philadelphia, PA 2000; Physicians' Desk Reference, 58^th Edition, Thompson, PDR, Montvale, NJ 2004; U.S. Patent Nos. 6,773,721; 7,053,107; 7,049,312 and Published U.S. Patent Application No. 20040224916; herein incorporated by reference).

At operation 2108, the packaging operation 240 may include packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents with one or more wrappers in administration form in response to at least one of the one or more parameters specifically associated with the individual. In some embodiments, one or more packaging units 1 14 may package at least one of the one or more pharmaceutical agents 1 12 and at least one of the one or more nutracentical agents 122 with one or more wrappers in administration form in response to at least one of the one or more parameters specifically associated with the individual 108.

In some embodiments, one or more pharmaceutical agents 1 12 and one or more nutraceutical agents 122 may be packaged by wrapping the one or more pharmaceutical agents 1 12 and one or more nutraceutical agents 122 into a single administration form for administration to an individual 108. In some embodiments, the one or more pharmaceutical agents 1 12 and one or more nutraceutical agents 122 may be preformulated prior to being wrapped in one or more wrappers. For example, one or more pharmaceutical agents 1 12 and/or one or more nutraceutical agents 122 that are each in tablet form may be wrapped into a single administration form. In other embodiments, the one or more pharmaceutical agents 112 and one or more nutraceutical agents 122 may be combined together and then wrapped in one or more wrappers. In other embodiments, one or more pharmaceutical agents 112 and one or more nutraceutical agents 122 may be combined together with a suitable carrier and then wrapped in one or more wrappers. Numerous materials may be used to wrap the one or more pharmaceutical agents 1 12 and one or more nutraceutical agents 122. Examples of such materials include, but are not limited to, polymers that include esters of cellulose and its derivatives (cellulose acetate phthalate, hydroxypropyl methylcellulose phthalate, hydroxypropyl methylcellulose acetate succinate), polyvinyl acetate phthalate, pH- sensitive methacrylic acid-methamethacrylate copolymers, shellac, and the like. Numerous water insoluble polymers may be used that include cellulose derivatives (i.e., ethylcellulose), polyvinyl acetate, neutral copolymers based on ethyl acrylate and methylmethacrylate, copolymers of acrylic and methacrylic acid esters with quaternary ammonium groups, and the like. In some embodiments, polymers used in forming the wrappers may be plasticized. Examples of plasticizers that may be used to plasticize the wrappers include, but are not limited to, triacetin, tributyl citrate, triethyl citrate, acetyl tri-n-butyl citrate diethyl phthalate, castor oil, dibutyl sebacate, acetylated monoglycerides, and the like and/or substantially any combination thereof. In some embodiments, the plasticizer may be present at about 3 to 30 weight percent and more typically about 10 to 25 weight percent based on the polymer to which the plasticizer is added. The type of plasticizer and its content depends on the polymer or polymers, nature of the coating system. In some embodiments, water-soluble nonipnic polysaccharide derivatives may be used to wrap the one or more pharmaceutical agents 112 and one or more nutraceutical agents 122. For example, hydroxypropylmethylcellulose, hydroxypropylcellulose, and/or sodium carboxymethylcellulose may be used. Such polymers form coatings that quickly dissolve in water and have a high permeability. Accordingly, in some embodiments, such polymers may be used for rapid release of one or more pharmaceutical agents 112 and/or one or more nutraceutical agents 122 that are wrapped in such a wrapper following administration to an individual 108. In some embodiments, one or more pharmaceutical agents 1 12 and/or one or more nutraceutical agents 122 may be wrapped in a wrapper that provides for sustained release of the one or more pharmaceutical agents 112 and/or one or more nutraceutical agents 122. For example, one or more pharmaceutical agents 112 and/or one or more nutraceutical agents 122 may be released continuously over twelve hours through use of wrappers constructed from ethyl cellulose and an ethyl acrylate-methyl methacrylate-ethyl trimethylammoniumchloride methacrylate copolymer as the release controlling wrapper. Methods and materials that may be used to prepare wrappers are known in the ait and are commercially available (i.e., Rohm Pharma, Piscataway, NJ; U.S. Patent Nos. 6,656,507; 7,048,945; 7,056,951; hereby incorporated by reference).

In some embodiments, one wrapper may be used to wrap one or more pharmaceutical agents 112 and one or more nutraceutical agents 122 into an administration form. For example, the one or more pharmaceutical agents 112 and one or more nutraceutical agents 122 may be combined together and then wrapped into an administration form in one wrapper for release at the same time following administration to an individual 108. In other embodiments, one continuous wrapper may be used to ^■ wrap one or more pharmaceutical agents 112 and one or more nutraceutical agents 122 into an administration form in which the one or more pharmaceutical agents 112 and one or more nutraceutical agents 122 are separated from each other. For example, in some embodiments, one of the one or more nutraceutical agents 122 may be covered with a continuous wrapper to form a core and then one of the one or more pharmaceutical agents 1 12 may be wrapped around the core with the continuous wrapper to produce an administration form. This process may be repeated with multiple pharmaceutical agents 1 12 and multiple nutraceutical agents 122 to form a miiltilayered administration form in which the multiple pharmaceutical agents 1 12 and multiple nutraceutical agents 122 are separated from each other. In some embodiments, one of the one or more pharmaceutical agents 112 may be covered with a continuous wrapper to form a core and then one of the one or more nutraceutical agents 122 may be wrapped around the core with the continuous wrapper to produce an administration form. This process may be repeated with multiple pharmaceutical agents 1 12 and multiple nutraceutical agents 122 to form a multilayered administration form in which the multiple pharmaceutical agents 1 12 and multiple nutraceutical agents 122 are separated from each other. In some embodiments, such a configuration provides for the release of pharmaceutical agents 112 and nutraceutical agents 122 from the administration form at different times and/or at different sites associated with an individual 108 to which the administration form is administered. In some embodiments, two or more pharmaceutical agents 112 are wrapped into an administration form together and additional nutraceutical agents 122 are wrapped into the administration form in separate layers. In some embodiments, two or more nutraceutical agents 122 are wrapped into an administration form together and additional pharmaceutical agents 112 are wrapped into the administration form in separate layers. In some embodiments, one or more pharmaceutical agents 112 and one or more nutraceutical agents 122 are wrapped into an administration form together and additional pharmaceutical agents 112 and/or nutraceutical agents 122 are wrapped into the administration form in separate layers. Accordingly, pharmaceutical agents 112 and nutraceutical agents 122 may be oriented in the administration form to be released from the administration form at the same time and/or site or such that they are released at different times and/or sites. Examples of such sites include, but are not limited to, the mouth, esophagus, stomach, duodenum, small intestine, large intestine, and the rectum. At operation 2110, the packaging operation 240 may include packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents within two or more concentric wrappers in administration form in response to at least one of the one or more parameters specifically associated with the individual. In some embodiments, one or more packaging units 1 14 may package at least one of the one or more pharmaceutical agents 1 12 and at least one of the one or more nutraceutical agents 122 within two or more concentric wrappers in administration form in response to at least one of the one or more parameters 106 specifically associated with the individual 108.

In some embodiments, one or more packaging units 1 14 may package the one or more pharmaceutical agents 112 and one or more nutraceutical agents 122 within two or more concentric wrappers for administration to an individual 108. In some embodiments, one or more pharmaceutical agents 1 12 and one or more nutraceutical agents 122 may be packaged by wrapping the one or more pharmaceutical agents 112 and one or more nutraceutical agents 122 within two or more wrappers to produce an administration form. In some embodiments, the same type of material is used to produce the two or more wrappers in the administration form. In some embodiments, different types of material are used as wrappers to produce the administration form. For example, an outer wrapper may be selected to dissolve rapidly and release one or more pharmaceutical agents 112 and/or one or more nutraceutical agents 122 soon after administration of the administration form to the individual 108 while an inner wrapper may be selected to release one or more pharmaceutical agents 1 12 and/or one or more nutraceutical agents 122 at a later time and/or at a different site associated with an individual 108. Accordingly, in some embodiments, multiple pharmaceutical agents 112 and multiple nutraceutical agents 122 may be packaged into the same administration form for release at different times and at different sites following administration of the administration form to an individual 108. In some embodiments, the pharmaceutical agents 112 may be the same to provide for continuous dosing of an individual 108. In some embodiments, the nutraceutical agents 122 may be the same to provide for continuous dosing of an individual 108. In some embodiments, the pharmaceutical agents 1 12 may be different to provide for dosing of an individual 108 with different pharmaceutical agents 112. In some embodiments, the nutraceutical agents 322 may be different to provide for dosing of an individual 108 with different nutraceutical agents 122. In some embodiments, some of the pharmaceutical agents 112 may be the same to provide for continuous dosing of an individual 108 and others may be different to provide for dosing of an individual 108 with different pharmaceutical agents 1 12. In some embodiments, some of the nutraceutical agents 122 may be the same to provide for continuous dosing of an individual 108 and others may be different to provide for dosing of an individual 108 with different nutraceutical agents 122. Accordingly, numerous combinations of pharmaceutical agents 1 12, nutraceutical agents 122, and wrappers may be assembled into an administration form.

FIG. 22 illustrates alternative embodiments of the example operational flow 200 of FIG. 2. FIG. 22 illustrates example embodiments where the packaging operation 240 may include at least one additional operation. Additional operations may include an operation 2202, operation 2204, operation 2206, and/or operation 2208.

At operation 2202, the packaging operation 240 may include packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents within two or more nested capsules and/or two or more non-nested capsules in administration form in response to at least one of the one or more parameters specifically associated with the individual. In some embodiments, one or more packaging units 114 may package at least one of the one or more pharmaceutical agents 1 12 and at least one of the one or more nutraceutical agents 122 within two or more nested capsules and/or two or more non-nested capsules in administration form in response to at least one of the one or more parameters 106 specifically associated with the individual 108.

In some embodiments, one or more pharmaceutical agents 112 and one or more nutraceutical agents 122 may be packaged into an administration form through use of nested capsules. In some embodiments, one or more pharmaceutical agents 112 and one or more nutraceutical agents 122 may be packaged into an administration form through use of non-nested capsules. In some embodiments, one or more first pharmaceutical agents 1 12 may be packaged in a first capsule and one or more second pharmaceutical agents 1 12 may be packaged in a second capsule in which the first capsule is included to create an administration form having nested capsules. In some embodiments, one or more first nutraceutical agents 122 may be packaged in a first capsule and one or more second nutraceutical agents 122 may be packaged in a second capsule in which the first capsule is included to create an administration form having nested- capsules. In some embodiments, one or more first pharmaceutical agents 1 12 may be packaged in a first capsule and one or more second nutraceutical agents 122 may be packaged in a second capsule in which the first capsule is included to create an administration form having nested capsules. In some embodiments, one or more first nutraceutical agents 122 may be packaged in a first capsule and one or more second pharmaceutical agents 1 12 may be packaged in a second capsule in which the first capsule is included to create an administration form having nested capsules. Accordingly, administration forms may be constructed that include two or more nested capsules. In some embodiments, the material used to construct the individual capsules of a single administration form is the same. In some embodiments, the material used to construct the individual capsules of a single administration form is different. In some embodiments, the material used to construct some of the individual capsules of a single administration form may be the same while the material used to construct other individual capsules of the single administration form may be different. Accordingly, through selection of materials used to construct the individual capsules contained in an administration form, one or more pharmaceutical agents 1 12 and/or one or more nutraceutical agents 122 may be released from one administration form at one or more times and/or at one or more sites associated with an individual 108. Examples of such sites include, but are not limited to, the mouth, esophagus, stomach, duodenum, small intestine, large intestine, and the rectum.

At operation 2204, the packaging operation 240 may include packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents within at least one tablet in administration form in response to at least one of the one or more parameters specifically associated with the individual. In some embodiments, one or more packaging units 114 may package at least one of the one or more pharmaceutical agents 112 and at least one of the one or more nutraceutical agents 122 within at least one tablet in administration form in response to at least one of the one or more parameters 106 specifically associated with the individual 108.

In some embodiments, one or more pharmaceutical agents 1 12 and one or more nutraceutical agents 122 may be selected in response to one or more parameters 106 specifically associated with an individual 108 and packaged into at least one table. Methods to package one or more pharmaceutical agents 1 12 into at least one tablet for administration to an individual 108 are known (i.e., Published U.S. Patent Application Nos. 20040224916 and 20050013863; and U.S. Patent Nos. 5,490,962; 6,280,771; herein incorporated by reference). Such methods may be used to package one or more pharmaceutical agents 112 and one or more nutraceutical agents^' 122 into at least one tablet for administration to an individual 108. Accordingly, in some embodiments, one or more pharmaceutical agents 112 and one or more nutraceutical agents 122 may be packaged into a tablet such that the one or more pharmaceutical agents 1 12 and one or more nutraceutical agents 122 are released at the same or different times following administration of the tablet to an individual 108. In other embodiments, one or more pharmaceutical agents 112 and one or more nutraceutical agents 122 may be packaged into a tablet such that the one or more pharmaceutical agents 112 and one or moi-e nutraceutical agents 122 are released at the same or different sites associated with an individual 108 following administration of the tablet to an individual 108. In other embodiments, one or more pharmaceutical agents 112 and one or more nutraceutical agents 122 may be packaged into a tablet such that the one or more pharmaceutical agents 112 and one or more nutraceutical agents 122 are released at the same or different times and at the same or different sites associated with an individual 108 following administration of the tablet to the individual 108.

At operation 2206, the packaging operation 240 may include packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents in unit dosage form. In some embodiments, one or more packaging ^' units 114 may package at least one of the one or more pharmaceutical agents 112 and at least one of the one or more nutraceutical agents 122 in unit dosage form.

The term "unit dosage form" refers to one or more amounts of one or more pharmaceutical agents 112 and/or one or more nutraceutical agents 122 that are suitable as unitary dosages for individuals, such as human and non-human individuals, with each unit containing a predetermined quantity of at least one pharmaceutical agent 112 and at least one nutraceutical agent 122 calculated to produce a desired effect, such as a therapeutic effect, in association with one or more suitable pharmaceutical carriers. Such unit dosage forms may be packaged in numerous configurations that include, but are not limited to, tablets, capsules, ampoules, and other administration forms known in the art and described herein. In some embodiments, two or more unit dosage forms of one or more pharmaceutical agents 1 12 and/or one or more nutraceutical agents 122 may be packaged into an administration form. For example, in some embodiments, two unit dosage forms may be wrapped into an administration form through use of a continuous wrapper such that they are released at different times following administration to an individual 108. In such an example, two unit dosage forms are included within one administration form. Accordingly, numerous combinations of pharmaceutical agents 1 12 and nutraceutical agents 122 may be packaged in unit dosage forms that may be included within an administration form.

At operation 2208, the packaging operation 240 may include packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents in oral administration form. In some embodiments, one or more packaging units 1 14 may package at least one of the one or more pharmaceutical agents 112 and at least one of the one or more nutraceutical agents 122 in oral administration form.

For oral administration, one or more pharmaceutical agents 112 and one or more nutraceutical agents 122 may be packaged into an oral administration form by combining the one or more pharmaceutical agents 1 12 and one or more nutraceutical agents 122 with pharmaceutically acceptable carriers that are well known in the art. Such earners allow the one or more pharmaceutical agents 1 12 and one or more nutraceutical agents 122 to be formulated as tablets, pills, dragees, capsules, liquids, gels, syrups, slurries, suspensions and the like, for oral ingestion by an individual 108. Oral administration forms can be obtained by combining the one or more pharmaceutical agents 112 and one or more nutraceutical agents 122 with a solid excipient, optionally grinding the resulting mixture, and processing the mixture of granules, after adding suitable auxiliaries, if desired, to obtain tablets or dragee cores. Suitable excipients are, in particular, fillers such as sugars, including lactose, sucrose, mannitol, or sorbitol; cellulose preparations such as, for example, maize starch, wheat starch, rice starch, potato starch, gelatin, gum tragacanth, methyl cellulose, hydroxypropylmethyl-celhilose, sodium carboxymethylcellulose, and/or polyvinylpyrrolidone. If desired, disintegrating agents may be added, such as the cross-linked polyvinyl pyrrolidone, agar, or alginic acid or a salt thereof such as sodium alginate.

Dragee cores are provided with suitable coatings. For this puipose, concentrated sugar solutions may be used, which may optionally contain gum arabic, talc, polyvinyl pyrrolidone, carbopol gel, polyethylene glycol, and/or titanium dioxide, lacquer solutions, and suitable organic solvents or solvent mixtures. Dyestuffs or pigments may be added to the tablets or dragee coatings for identification or to characterize different combinations of pharmaceutical agents 1 12 and nutraceutical agents 122.

Oral administration forms may include push-fit capsules made of gelatin, as well as soft, sealed capsules made of gelatin and a plasticizer, such as glycerol or sorbitol. The push-fit capsules can contain one or more pharmaceutical agents 112 and one or more nutraceutical agents 122 in admixture with a filler such as lactose, binders such as starches, and/or lubricants such as talc or magnesium stearate and, optionally, stabilizers. In soft capsules, the pharmaceutical agents 1 12 and nutraceutical agents 122 may be dissolved or suspended in suitable liquids, such as fatty oils, liquid paraffin, or liquid polyethylene glycols. In addition; stabilizers may be added. AU oral dosage forms may be prepared in dosages suitable for such administration. For buccal administration, the pharmaceutical agents 112 and nutraceutical agents 122 may take the form of tablets or lozenges formulated in a conventional manner.

FIG. 23 illustrates alternative embodiments of the example operational flow 200 of FIG. 2. FIG. 23 illustrates example embodiments where the packaging operation 240 may include at least one additional operation. Additional operations may include an operation 2302, operation 2304, operation 2306, and/or operation 2308.

At operation 2302, the packaging operation 240 may include packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents in response to a sustained release profile. In some embodiments, one or more packaging units 1 14 may package at least one of the one or more pharmaceutical agents 1 12 and at least one of the one or more nutraceutical agents 122 in response to a sustained release profile.

In some embodiments, one or more pharmaceutical agents 112 and one or more nutraceutical agents 122 may be packaged with a carrier that may include a time-delay or time-release material known in the art, such as glyceryl monostearate or glyceryl distearate alone or with a wax, ethylcellulose, hydroxypropylmethylcellulose, methylmethacrylate and the like. Additionally, in some embodiments, one or more pharmaceutical agents 1 12 and one or more nutraceutical agents 122 may be administered using a sustained-release system, such as semipermeable matrices of solid hydrophobic polymers containing the one or more pharmaceutical agents 1 12 and one or more nutraceutical agents 122. Various sustained-release materials are known and have been described. For example, sustained-release capsules may, depending on their chemical composition, release one or more pharmaceutical agents 1 12 and one or more nutraceutical agents 122 for a few weeks up to over 100 days. Numerous additional sustained-release formulations are known and have been described (i.e., U.S. Patent Nos. 7,041,670; 7,041 ,317; 6,709,676; herein incorporated by reference).

At operation 2304, the packaging operation 240 may include packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents in storage material. In some embodiments, one or more packaging units 1 14 may package at least one of the one or more pharmaceutical agents 112 and at least one of the one or more nutraceutical agents 122 in storage material.

One or more pharmaceutical agents 112 and one or more nutraceutical agents 122 may be packaged in numerous types of storage material. Examples of storage material include, but are not limited to, containers, boxes, ampoules, vials, syringes, and the like. In some embodiments, storage material includes advertising. In some embodiments, storage material includes instructions for administration. Such instructions may include, but are not limited to, time for administration, route of administration, the name of the individual 108 to whom the one or more pharmaceutical agents 112 and/or one or more nutraceutical agents 122 are to be administered, the identity of the one or more pharmaceutical agents 112 and/or the one or more nutraceutical agents 122, the dosage of the one or more pharmaceutical agents 112 and/or one or more nutraceutical agents 122, appropriate buffers for suspension of the one or more pharmaceutical agents 112 and/or one or more nutraceutical agents 122, the source of the one or more pharmaceutical agents 1 12 and/or one or more nutraceutical agents 122, the name of a physician or physicians who prescribed the one or more pharmaceutical agents 1 12, the date when the one or more pharmaceutical agents ] 12 were prescribed, the date when the one or more pharmaceutical agents 1 12 and/or one or more nutraceutical agents 122 were packaged, the date when the one or more pharmaceutical agents 1 12 and/or one or more nutraceutical agents 122 were manufactured, the expiration date of the one or more pharmaceutical agents 112 and/or one or more nutraceutical agents 122, and substantially any combination thereof.

At operation 2306, the packaging operation 240 may include labeling at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents. In some embodiments, one or more packaging units 114 may label at least one of the one or more pharmaceutical agents 1 12 and at least one of the one or more nutraceutical agents 122.

In some embodiments, one or more packaging units 1 14 may place a label directly on one or more of the pharmaceutical agents 112 and/or one or more nutraceutical agents 122. Numerous methods may be used to label one or more pharmaceutical agents 1 12 and/or one or more nutraceutical agents 122. For example, in some embodiments, one or more labeling units may stamp an indented label into one or more pharmaceutical agents 1 12 and/or one or more nutraceutical agents 122. In some embodiments, one or more packaging units 114 may stamp a label onto one or more pharmaceutical agents 112 and/or one or more nutraceutical agents 122 through use of one or more edible dyes. Such labels may include numerous types of information. For example, such labels may indicate the manufacturer of one or more pharmaceutical agents 112 and/or one or more nutraceutical agents 122, the date of manufacture, the date of packaging, the dosage, the route of administration, and the like. Such labels may be in substantially any language. In some embodiments, at least one label may be a bar code.

At operation 2308, the packaging operation 240 may include labeling storage material containing at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents. In some embodiments, one or more packaging units 114 may label storage material containing at least one of the one or more pharmaceutical agents 1 12 and at least one of the one or more nutraceiitical agents 122.

In some embodiments, storage material may be labeled with advertising. In some embodiments, storage material may be labeled with instructions for administration. Such instructions may include, but are not limited to, time for administration, route of administration, the name of the individual 108 to whom the one or more pharmaceutical agents 1 12 and/or one or more nutraceutical agents 122 are to be administered, the identity of the one or more pharmaceutical agents 1 12 and/or one or more nutraceutical agents 122, the dosage of the one or more pharmaceutical agents 1 12 and/or one or more nutraceutical agents 122, appropriate buffers for suspension of the one or more pharmaceutical agents 1 12 and/or one or more nutraceutical agents 122, the source of the one or more pharmaceutical agents 112 and/or one or more nutraceutical agents 122, the name of a physician or physicians who prescribed the one or more pharmaceutical agents 1 12, the date when the one or more pharmaceutical agents 112 were prescribed, the date when the one or more pharmaceutical agents 112 and/or one or more nutraceutical agents 122 were packaged, the date when the one or more pharmaceutical agents 112 and/or one or more nutraceutical agents 122 were manufactured, the expiration date of the one or more pharmaceutical agents 1 12 and/or one or more nutraceutical agents 122, and substantially any combination thereof.

FIG. 24 illustrates a system 2400 representing examples of circuitry that is related to systems for individualized pharmaceutical and nutraceutical selection and packaging. In FIG. 24 discussion and explanation may be provided with respect to the above- described example of FIG. 1, and/or with respect to other examples and contexts. However, it should be understood that the circuitry may be assembled in a number of other environments and contexts, and/or modified versions of FIG. 1. Also, although various circuitry is presented in the sequence(s) illustrated, it should be understood that circuitry may be assembled in other configurations than those which are illustrated. After a start operation, the system 2400 includes a circuitry block 2410 that includes circuitry for accepting input of one or more parameters specifically associated with an individual. In some embodiments, the circuitry may be used to accept input 104 of one or more parameters 106 associated with an individual 108. In some embodiments, the circuitry may be included within one or more accepting units 102 that accept input 104 of one or more parameters 106 associated with an individual 108.

In some embodiments, an individual 108 may be a human. In some embodiments, an individual 108 may be a non-human animal. Examples of such non-human animals include, but are not limited to, domestic pets such as dogs, cats, horses, potbelly pigs, ferrets, rodents, reptiles, amphibians, and the like. Non-human animals also include animals that include, but are not limited to, cattle, sheep, goats, chickens, pigs, and the like. Accordingly, the systems and methods described herein may be used in association with substantially any human and/or non-human animal.

Numerous parameters 106 may be associated with an individual 108. Such parameters 106 may include, but are not limited to, physical characteristics, metabolic characteristics, financial characteristics, and the like. Examples of parameters 106 include, an individual's height, weight, gender, kidney function, liver function, level of physical fitness, age, allergic response, metabolic level (i.e., resting metabolic rate and/or activity -related metabolic rate), disease state, body fat percentage, personal health habits (i.e., smoking, alcohol consumption, diet, illegal drug use, and the like), family health history, insurance coverage, food supplement usage, pharmaceutical agent 112 usage, nutraceutical agent 122 usage, non-prescription drug use, pregnancy status, and the like.

Numerous technologies may be used to provide input 104 that include one or more parameters 106 associated with an individual 108. Examples of such technologies include, but are not limited to, hardwired input 104, wireless input 104, computer input 104, telephonic input 104, internet based input 104, intranet based input 104, digital input 104, analog input 104, input 104 from a human, input 104 from a paltn held organizer, input 104 from a personal digital assistant, input 104 from a web enabled cellular telephone, and the like. In some embodiments, one or more accepting units 102 accept input 104 from one source. In some embodiments, one or more accepting units 102 accept input 104 from more than one source. For example, in some embodiments, an accepting unit 102 may accept input 104 from an insurance company, a physician, a pharmacist, a clinical laboratory and a nutraceutical company. In some embodiments, input 104 may be associated with, but not limited to, a physician input 104, a pharmacist input 104, a patient input 104, a machine input 104 and/or substantially any combination thereof.

In some embodiments, an accepting unit 102 may include an input device. For example, in some embodiments, an accepting unit 102 may include an interface, such as a keyboard, touch-screen and/or the like, where parameters 106 associated with an individual 108 may be input 104 directly into the accepting unit 102. In some embodiments, an accepting unit 102 may lack an interface where parameters 106 associated with an individual 108 may be directly input 104 into the accepting unit 102. In some embodiments, an accepting unit 102 may accept input 104 of one or more parameters 106 associated with an individual 108 from one or more locations that are remote from the accepting unit 102. For example, in some embodiments, an accepting unit 102 may accept input 104 from a wireless device, the internet, an intranet, a telephone, a palrn held organizer, input 104 from a personal digital assistant, input 104 from a web enabled cellular telephone, and the like.

After a start operation, the system 2400 includes a circuitry block 2420 that includes circuitry for selecting one or more pharmaceutical agents in response to at least one of the one or more parameters specifically associated with the individual. In some embodiments, the circuitry may be used to select one or more pharmaceutical agents 112 in response to at least one of the one or more parameters 106 specifically associated with the individual 108. In some embodiments, the circuitry may be included within one or more selecting units 1 10 that can be used to select one or more pharmaceutical agents 112 in response to at least one of the one or more parameters 106 specifically associated with the individual 108. In some embodiments, one or more selecting units 110 may select one or more first pharmaceutical agents 1 12 in response to at least one of the one or more parameters 106 specifically associated with an individual 108 and select one or more second pharmaceutical agents 112 based on the identity of the one or more first nutraceutical agents 112 selected. For example, in some embodiments, one or more selecting units 1 10 may select the first and second nutraceutical agents 112 to act synergistically with each other when administered to an individual 108. In some embodiments, one or more selecting units 1 10 may select one or more first nutraceutical agents 1 12 and one or more second nutraceutical agents 112 so that they do not contraindicate each other when administered to an individual 108. One or more nutraceutical agents 112 may be selected in response to numerous parameters 106. After a start operation, the system 2400 includes a circuitry block 2430 that includes circuitry for selecting one or more nutraceutical agents in response to at least one of the one or more parameters specifically associated with the individual. In some embodiments, the circuitry may be used to select one or more nutraceutical agents 122 in response to at least one of the one or more parameters 106 specifically associated with the individual 108. In some embodiments, the circuitry may be included within one or more selecting units 1 10 that can be used to select one or more nutraceutical agents 122 in response to at least one of the one or more parameters 106 specifically associated with the individual 108. In some embodiments, one or more selecting units 1 10 may select one or more first nutraceutical agents 122 in response to at least one of the one or more parameters 106 specifically associated with an individual 108 and select one or more second nutraceutical agents 122 based on the identity of the one or more first nutraceutical agents 122 selected. For example, in some embodiments, one or more selecting units 1 10 may select one or more first nutraceutical agents 122 and one or more second nutraceutical agents 122 to act synergistically with each other when administered to an individual 108. In some embodiments, one or more selecting units 110 may select one or more first nutraceutical agents 122 and one or more second nutraceutical agents 122 so that they do not contraindicate each other when administered to an individual 108. One or more nutraceutical agents 122 may be selected in response to numerous parameters 106.

After a start operation, the system 2400 includes a circuitry block 2440 that includes circuitry for packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents in administration form in response to at least one of the one or more parameters specifically associated with the individual. In some embodiments, the circuitry may be used to package at least one of the one or more pharmaceutical agents 1 12 and at least one of the one or more nutraceutical agents 122 in administration form in response to at least one of the one or more parameters 106 specifically associated with the individual 108. In some embodiments, the circuitry may be included within one or more packaging units 114.

Numerous types of packaging units 1 14 may be used to package at least one of the one or more pharmaceutical agents 1 12 and at least one of the one or more nutraceutical agents 122. In some embodiments, one packaging unit 114 may be used to package one or more pharmaceutical agents 1 12 and one or more nutraceutical agents 122. In some embodiments, one or more packaging.itnits 1 14 may be used to package one or more pharmaceutical agents 1 12 and one or more nutraceutical agents 122. In some embodiments, a first packaging unit 1 14 may package one or more pharmaceutical agents 1 12, a second packaging unit 1 14 may package one or more nutraceutical agents 122, and a third packaging unit 1 14 may package the one or more pharmaceutical agents 1 12 and the one or more nutraceutical agents 1 12 into an admistration form.

FlG. 25 illustrates a partial view of a system 2500 that includes a computer program 2504 for executing a computer process on a computing device. An embodiment of the system 2500 is provided using a signal-bearing medium 2502 bearing at least one of one or more instructions for accepting input of one or more parameters specifically associated with an individual, one or more instructions for selecting one or more pharmaceutical agents in response to at least one of the one or more parameters specifically associated with the individual, one or more instructions for selecting one or more nutraceutical agents in response to at least one of the one or more parameters specifically associated with the individual, and one or more instructions for packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents in administration form in response to at least one of the one or more parameters specifically associated with the individual. The one or more instructions may be, for example, computer executable and/or logic-implemented instructions. In some embodiments, the signal-bearing medium 2502 may include a computer-readable medium 2506. In some embodiments, the signal bearing medium 2502 may include a recordable medium 25208. In some embodiments, the signal bearing medium 2502 may include a communications medium 2510.

With respect to the use of substantially any plural and/or singular terms herein, those having skill in the art can translate from the plural to the singular and/or from the singular to the plural as is appropriate to the context and/or application. The various singular/plural permutations are not expressly set forth herein for sake of clarity.

While particular aspects of the present subject matter described hez'ein have been shown and described, it will be apparent to those skilled in the art that, based upon the teachings herein, changes and modifications may be made without departing from the subject matter described herein and its broader aspects and, therefore, the appended claims are to encompass within their scope all such changes and modifications as are within the true spirit and scope of the subject matter described herein. Furthermore, it is to be understood that the invention is defined by the appended claims. It will be understood by those within the art that, in general, terms used herein, and especially in the appended claims (e.g., bodies of the appended claims) are generally intended as "open" terms (e.g., the term "including" should be interpreted as "including but not limited to," the term "having" should be interpreted as "having at least," the term "includes" should be interpreted as "includes but is not limited to," etc.). It will be further understood by those within the art that if a specific number of an introduced claim recitation is intended, such an intent will be explicitly recited in the claim, and in the absence of such recitation no such intent is present. For example, as an aid to understanding, the following appended claims may contain usage of the introductory phrases "at least one" and "one or more" to introduce claim recitations. However, the use of such phrases should not be construed to imply that the introduction of a claim recitation by the indefinite articles "a" or "an" limits any particular claim containing such introduced claim recitation to inventions containing only one such recitation, even when the same claim includes the introductory phrases "one or more" or "at least one" and indefinite articles such as "a" or "an" (e.g., "a" and/or "an" should typically be interpreted to mean "at least one" or "one or more"); the same holds true for the use of definite articles used to introduce claim recitations. In addition, even if a specific number of an introduced claim recitation is explicitly recited, those skilled in the art will recognize that such recitation should typically be interpreted to mean at least the recited number (e.g., the bare recitation of "two recitations," without other modifiers, typically means at least two recitations, or two or more recitations). Furthermore, in those instances where a convention analogous to "at least one of A, B, and C, etc." is used, in general such a construction is intended in the sense one having skill in the art would understand the convention (e.g., " a system having at least one of A, B, and C" would include but not be limited to systems that have A alone, B alone, C alone, A and B together, A and C together, B and C together, and/or A, B, and C together, etc.). In those instances where a convention analogous to "at least one of A, B, or C, etc." is used, in general such a construction is intended in the sense one having skill in the art would understand the convention (e.g., " a system having at least one of A, B, or C" would include but not be limited to systems that have A alone, B alone, C alone, A and B together, A and C together, B and C together, and/or A, B, and C together, etc.). It will be further understood by those within the art that virtually any disjunctive word and/or phrase presenting two or more alternative terms, whether in the description, claims, or drawings, should be understood to contemplate the possibilities of including one of the terms, either of the terms, or both terms. For example, the phrase "A or B" will be understood to include the possibilities of "A" or "B" or "A and B."

Those having skill in the art will recognize that the state of the art has progressed to the point where there is little distinction left between hardware and software implementations of aspects of systems; the use of hardware or software is generally (but not always, in that in certain contexts the choice between hardware and software can become significant) a design choice representing cost vs. efficiency tradeoffs. Those having skill in the art will appreciate that there are various vehicles by which processes and/or systems and/or other technologies described herein can be effected (e.g., hardware, software, and/or firmware), and that the preferred vehicle will vary with the context in which the processes and/or systems and/or other technologies are deployed. For example, if an implementer determines that speed and accuracy are paramount, the implementer may opt for a mainly hardware and/or firmware vehicle; alternatively, if flexibility is paramount, the implementer may opt for a mainly software implementation; or, yet again alternatively, the implementer may opt for some combination of hardware, software, and/or firmware. Hence, there are several possible vehicles by which the processes and/or devices and/or other technologies described herein may be effected, none of which is inherently superior to the other in that any vehicle to be utilized is a choice dependent upon the context in which the vehicle will be deployed and the specific concerns (e.g., speed, flexibility, or predictability) of the implementer, any of which may vary. Those skilled in the art will recognize that optical aspects of implementations will typically employ optically-oriented hardware, software, and or firmware.

The foregoing detailed description has set forth various embodiments of the devices and/or processes via the use of block diagrams, flowcharts, and/or examples. Insofar as such block diagrams, flowcharts, and/or examples contain one or more functions and/or operations, it will be understood by those within the art that each function and/or operation within such block diagrams, flowcharts, or examples can be implemented, individually and/or collectively, by a wide range of hardware, software, firmware, or virtually any combination thereof. In one embodiment, several portions of the subject matter described herein may be implemented via Application Specific Integrated Circuits (ASICs), Field Programmable Gate Arrays (FPGAs), digital signal processors (DSPs), or other integrated formats. However, those skilled in the art will recognize that some aspects of the embodiments disclosed herein, in whole or in part, can be equivalently implemented in integrated circuits, as one or more computer programs running on one or more computers (e.g., as one or more programs running on one or more computer systems), as one or more programs running on one or more processors (e.g., as one or more programs running on one or more microprocessors), as firmware, or as virtually any combination thereof, and that designing the circuitry and/or writing the code for the software and or firmware would be well within the skill of one of skill in the art in light of this disclosure. In addition, those skilled in the art will appreciate that the mechanisms of the subject matter described herein are capable of being distributed as a program product in a variety of forms, and that an-illustrative embodiment of the subject matter described herein applies regardless of the particular type of signal bearing medium used to actually carry out the distribution. Examples of a signal bearing medium include, but are not limited to, the following: a recordable type medium such as a floppy disk, a hard disk drive, a Compact Disc (CD), a Digital Video Disk (DVD), a digital tape, a computer memory, etc.; and a transmission type medium such as a digital anαVor an analog communication medium (e.g., a fiber optic cable, a waveguide, a wired communications link, a wireless communication link, etc.).

In a general sense, those skilled in the ait will recognize that the various embodiments described herein can be implemented, individually and/or collectively, by various types of electro-mechanical systems having a wide range of electrical components such as hardware, software, firmware, or virtually any combination thereof; and a wide range of components that may impart mechanical force or motion such as rigid bodies, spring or torsional bodies, hydraulics, and electro-magnetically actuated devices, or virtually any combination thereof. Consequently, as used herein "electromechanical system" includes, but is not limited to, electrical circuitry operably coupled with a transducer (e.g., an actuator, a motor, a piezoelectric crystal, etc.), electrical circuitry having at least one discrete electrical circuit, electrical circuitry having at least one integrated circuit, electrical circuitry having at least one application specific integrated circuit, electrical circuitry forming a general purpose computing device configured by a computer program (e.g., a general purpose computer configured by a computer program which at least partially carries out processes and/or devices described herein, or a microprocessor configured by a computer program which at least partially carries out processes and/or devices described herein), electrical circuitry forming a memory device (e.g., forms of random access memory), electrical circuitry forming a communications device (e.g., a modem, communications switch, or optical-electrical equipment), and any non-electrical analog thereto, such as optical or other analogs. Those skilled in the art will also appreciate that examples of electro-mechanical systems include but are not limited to a variety of consumer electronics systems, as well as other systems such as motorized transport systems, factory automation systems, security systems, and communication/computing systems. Those skilled in the art will recognize that electro-mechanical as used herein is not necessarily limited to a system that has both electrical and mechanical actuation except as context may dictate otherwise.

In a general sense, those skilled in the art will recognize that the various aspects described herein which can be implemented, individually and/or collectively, by a wide range of hardware, software, firmware, or any combination thereof can be viewed as being composed of various types of "electrical circuitry." Consequently, as used herein "electrical circuitry" includes, but is not limited to, electrical circuitry having at least one discrete electrical circuit, electrical circuitry having at least one integrated circuit, electrical circuitry having at least one application specific integrated circuit, electrical circuitry forming a general purpose computing device configured by a computer program (e.g., a general puipose computer configured by a computer program which at least partially carries out processes and/or devices described herein, or a microprocessor configured by a computer program which at least partially carries out processes and/or devices described herein), electrical circuitry forming a memory device (e.g., forms of random access memory), and/or electrical circuitry forming a communications device (e.g., a modem, communications switch, or optical-electrical equipment). Those having skill in the art will recognize that the subject matter described herein may be implemented in an analog or digital fashion or some combination thereof.

Those skilled in the art will recognize that it is common within the art to implement devices and/or processes and/or systems in the fashion(s) set forth herein, and thereafter use engineering and/or business practices to integrate such implemented devices and/or processes and/or systems into more comprehensive devices and/or processes and/or systems. That is, at least a portion of the devices and/or processes and/or systems described herein can be integrated into other devices and/or processes and/or systems via a reasonable amount of experimentation. Those having skill in the art will recognize that examples of such other devices and/or processes and/or systems might include - as appropriate to context and application — all or part of devices and/or processes and/or systems of (a) an air conveyance (e.g., an airplane, rocket, hovercraft, helicopter, etc.), (b) a ground conveyance (e.g., a car, truck, locomotive, tank, armored personnel carrier, etc.), (c) a building (e.g., a home, warehouse, office, etc.), (d) an appliance (e.g., a refrigerator, a washing machine, a dryer, etc.), (e) a communications system (e.g., a networked system, a telephone system, a voice-over IP system, etc.), (f) a business entity (e.g., an Internet Service Provider (ISP) entity such as Comcast Cable, Quest, Southwestern Bell, etc), or (g) a wired/wireless services entity such as Sprint, Cingular, Nextel, etc.), etc.

Although user 120 is shown/described herein as a single illustrated figure, those skilled in the art will appreciate that a user 120 may be representative of a human user, a robotic user 120 (e.g., computational entity), and/or substantially any combination thereof (e.g., a user 120 may be assisted by one or more robotic agents). In addition, a user 120 as set forth herein, although shown as a single entity may in fact be composed of two or more entities. Those skilled in the art will appreciate that, in general, the same may be said of "sender" and/or other entity-oriented terms as such terms are used herein.

The herein described subject matter sometimes illustrates different components contained within, or connected with, different other components. It is to be understood that such depicted architectures are merely exemplary, and that in fact many otlier architectures can be implemented which achieve the same functionality. In a conceptual sense, any arrangement of components to achieve the same functionality is effectively "associated" such that the desired functionality is achieved. Hence, any two components herein combined to achieve a particular functionality can be seen as "associated with" each other such that the desired functionality is achieved, irrespective of architectures or intermedial components. Likewise, any two components so associated can also be viewed as being "operably connected", or "operably coupled", to each other to achieve the desired functionality, and any two components capable of being so associated can also be viewed as being "operably couplable", to each other to achieve the desired functionality. Specific examples of operably couplable include but are not limited to physically mateable and/or physically interacting components and/or wirelessly interactable and/or wirelessly interacting components and/or logically interacting and/or logically interactable components.

All publications, patents and patent applications cited herein are incorporated herein by reference. The foregoing specification has been described in relation to certain embodiments thereof, and many details have been set forth for purposes of illustration, however, it will be apparent to those skilled in the ait that the invention is susceptible to additional embodiments and that certain of the details described herein may be varied considerably without departing from the basic principles of the invention.

Claims

What is claimed is:

I. A method comprising: accepting input of one or more parameters specifically associated with an individual; selecting one or more pharmaceutical agents in response to at least one of the one or more parameters specifically associated with the individual; selecting one or more nutraceutical agents in response to at least one of the one or more parameters specifically associated with the individual; and packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents in administration form in response to at least one of the one or more parameters specifically associated with the individual.

2. The method of claim 1, wherein the accepting input of one or more parameters specifically associated with an individual comprises: accepting the one or more parameters specifically associated with a human individual.

3. The method of claim 1, wherein the accepting input of one or more parameters specifically associated with an individual comprises: accepting the one or more parameters specifically associated with a non-human individual.

4. The method of claim 1, wherein the accepting input of one or more parameters specifically associated with an individual comprises: accepting the one or more parameters specifically associated with a physician input.

5. The method of claim 1, wherein the accepting input of one or more parameters specifically associated with an individual comprises: accepting the one or more parameters specifically associated with a veterinarian input.

6. The method of claim 1, wherein the accepting input of one or more parameters specifically associated with an individual comprises: accepting the one or more parameters specifically associated with a pharmacist input.

7. The method of claim 1 , wherein the accepting input of one or more parameters specifically associated with an individual comprises: accepting the one or more parameters specifically associated with a patient input.

8. The method of claim I₅ wherein the accepting input of one or more parameters specifically associated with an individual comprises: accepting the one or more parameters specifically associated with a machine input.

9. The method of claim 1, wherein the accepting input of one or more parameters specifically associated with an individual comprises: accepting the one or more parameters specifically associated with at least one of a nutritionist input, a regimen subscription input, a regimen specification input, a recommending party input, a recommending entity input, an advising party input, or an advising entity input.

10. The method of claim 1, wherein the selecting one or more pharmaceutical agents in response to at least one of the one or more parameters specifically associated with the individual comprises: seiecting at least one of the one or more pharmaceutical agents in response to the selecting one or more nutraceutica] agents in response to at least one of the one or more parameters specifically associated with the individual.

11 , The method of claim 1 , wherein the selecting one or more pharmaceutical agents in response to at least one of the one or more parameters specifically associated with the individual comprises: selecting at least one of the one or more pharmaceutical agents in response to at least one condition specifically associated with the individual.

12. The method of claim 1 1, wherein the selecting one or more pharmaceutical agents in response to at least one of the one or more parameters specifically associated with the individual comprises: seiecting at least one of the one or more pharmaceutical agents in response to at least one condition specifically associated with the individual wherein the at least one condition includes at least one of attentiveness, alertness, test performance, relaxation, pain, fever, anxiety, fall, injury, accident, bite, bleeding, inflammation, infection, drowsiness, insomnia, discomfort, stress, grooming, appearance, capability, performance, improvement, enhancement, curtailment, wellbeing, vitality, vigor, disability, phobia, malady, psychosis, environmental extremes, environmental exposure, dysfunction, disease symptom, chronic condition, mental acuity, emotional behavior, physical prowess, addiction, obsession, therapy, remedy, behavior, nutrition, diet, exercise, immunization, prevention, diagnosis, subscription, regimen, goal to be achieved, or treatment.

13. The method of claim 1, wherein the selecting one of more pharmaceutical agents in response to at least one of the one or more parameters specifically associated with the individual comprises: selecting at least one of the one or more pharmaceutical agents in response to at least one dosage specifically associated with the individual.

14. The method of claim 1, wherein the selecting one or more pharmaceutical agents in response to at least one of the one or more parameters specifically associated with the individual comprises: selecting at least one of the one or more pharmaceutical agents in response to dosage of at least one of the one or more pharmaceutical agents.

15. The method of claim 1, wherein the selecting one or more pharmaceutical agents in response to at least one of the one or more parameters specifically associated with the individual comprises: selecting at least one of the one or more pharmaceutical agents in response to at least one time of administration.

16. The method of claim 1, wherein the selecting one or more pharmaceutical agents in response to at least one of the one or more parameters specifically associated with the individual comprises: selecting at least one of the one or more pharmaceutical agents in response to two or more times of administration within a time period.

17. The method of claim I, wherein the selecting one or more pharmaceutical agents in response to at least one of the one or more parameters specifically associated with the individual comprises: selecting at least one of the one or more pharmaceutical agents in response to one or more sites of administration specifically associated with the individual.

18. The method of claim 1, wherein the selecting one or more pharmaceutical agents in response to at least one of the one or more parameters specifically associated with the individual comprises: selecting at least one of the one or more pharmaceutical agents in response to one or more sites of release specifically associated with the individual.

19. The method of claim 1, wherein the selecting one or more pharmaceutical agents in response to at least one of the one or more parameters specifically associated with the individual comprises: selecting at least one of the one or more pharmaceutical agents in response to one or more physiological characteristics specifically associated with the individual.

20. The method of claim 1, wherein the selecting one or more pharmaceutical agents in response to at least one of the one or more parameters specifically associated with the individual comprises: selecting at least one of the one or more pharmaceutical agents in response to cost associated with at least one of the one or more pharmaceutical agents.

21. The method of claim 1, wherein the selecting one or more pharmaceutical agents in response to at least one of the one or more parameters specifically associated with the individual comprises: selecting at least one of the one or more pharmaceutical agents in response to compatibility of at least one of the pharmaceutical agents with another of the one or more pharmaceutical agents.

22. The method of claim 1 , wherein the selecting one or more nutraceutical agents in response to at least one of the one or more parameters specifically associated with the individual comprises: selecting at least one of the one or more nutraceutical agents in response to the selecting one or more pharmaceutical agents in response to at least one of the one or more parameters specifically associated with the individual.

23. The method of claim 1, wherein the selecting one or more nutraceutical agents in response to at least one of the one or more parameters specifically associated with the individual comprises: selecting at least one of the one or more nutraceutical agents in response to at least one condition specifically associated with the individual.

24. The method of claim 23, wherein the selecting one or more nutraceutical agents in response to at least one of the one or more parameters specifically associated with the individual comprises: selecting at least one of the one or more nutraceutical agents in response to at least one condition specifically associated with the individual wherein the at least one condition includes at least one of attentiveness, alertness, test performance, relaxation, pain, fever, anxiety, fall, injury, accident, bite, bleeding, inflammation, infection, drowsiness, insomnia, discomfort, stress, grooming, appearance, capability, performance, improvement, enhancement, curtailment, wellbeing, vitality, vigor, disability, phobia, malady, psychosis, environmental extremes, environmental exposure, dysfunction, disease symptom, chronic condition, mental acuity, emotional behavior, physical prowess, addiction, obsession, therapy, remedy, behavior, nutrition, diet, exercise, immunization, prevention, diagnosis, subscription, regimen, goal to be achieved, or treatment.

25. The method of claim 1 , wherein the selecting one or more nutraceutical agents in response to at least one of the one or more parameters specifically associated with the individual comprises: selecting at least one of the one or more nutraceutical agents in response to at least one dosage specifically associated with the individual.

26. The method of claim 1, wherein the selecting one or more nutraceutical agents in response to at least one of the one or more parameters specifically associated with the individual comprises: selecting at least one of the one or more nutraceutical agents in response to dosage of at least one of the one or more nutraceutical agents.

27. The method of claim 1, wherein the selecting one or more nutraceutical agents in response to at least one of the one or more parameters specifically associated with the individual comprises: selecting at least one of the one or more nutraceutical agents in response to at least one time of administration.

28. The method of claim 1, wherein the selecting one or more nutraceutical agents in response to at least one of the one or more parameters specifically associated with the individual comprises: selecting at least one of the one or more nutraceutical agents in response to two or more times of administration within a time period.

29. The method of claim 1, wherein the selecting one or more nutraceutical agents in response to at least one of the one or more parameters specifically associated with the individual comprises: selecting at least one of the one or more mitraceutical agents in response to one or more sites of administration specifically associated with the individual.

30. The method of claim 1 , wherein the selecting one or more nutraceutical agents in response to at least one of the one or more parameters specifically associated with the individual comprises: selecting at least one of the one or more nutraceutical agents in response to one or more sites of release specifically associated with the individual.

31. The method of claim 1, wherein the selecting one or more nutraceutical agents in response to at least one of the one or more parameters specifically associated with the individual comprises: selecting at least one of the one or more nutraceutical agents in response to one or more physiological characteristics specifically associated with the individual.

32. The method of claim 1, wherein the selecting one or more nutraceutical agents in response to at least one of the one or more parameters specifically associated with the individual comprises: selecting at least one of the one or more nutraceutical agents in response to cost associated with at least one of the one or more nutraceutical agents.

33. The method of claim 1, wherein the selecting one or more nutraceutical agents in response to at least one of the one or more parameters specifically associated with the individual comprises: selecting at least one of the one or more nutraceutical agents in response to compatibility of at least one of the nutraceutical agents with another of the one or more nutraceutical agents.

34. The method of claim 1 , wherein the packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents in administration form in response to at least one of the one or more parameters specifically associated with the individual comprises: packaging at least one of the one or more pharmaceutical agents with one or more pharmaceutically acceptable carriers or excipients.

35. The method of claim 1, wherein the packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents in administration form in response to at least one of the one or more parameters specifically associated with the individual comprises: packaging at least one of the one or more pharmaceutical agents with one or more wrappers in administration form in response to at least one of the one or more parameters specifically associated with the individual.

36. The method of claim 1, wherein the packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents in administration form in response to at least one of the one or more parameters specifically associated with the individual comprises: packaging at least one of the one or more pharmaceutical agents within two or more concentric wrappers in administration form in response to at least one of the one or more parameters specifically associated with the individual.

37. The method of claim 1, wherein the packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents in administration form in response to at least one of the one or more parameters specifically associated with the individual comprises: packaging at least one of the one or more pharmaceutical agents within two or more nested capsules and/or two or moi'e non-nested capsules in administration form in response to at least one of the one or more parameters specifically associated with the individual.

38. The method of claim 1, wherein the packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents in administration form in response to at least one of the one or more parameters specifically associated with the individual comprises: packaging at least one of the one or more pharmaceutical agents within at least one tablet in administration form in response to at least one of the one or more parameters specifically associated with the individual.

39. The method of claim 1, wherein the packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents in administration form in response to at least one of the one or more parameters specifically associated with the individual comprises: packaging at least one of the one or more pharmaceutical agents with one or more pharmaceutically acceptable poloxamers, humectants, binders, disintegrants, fillers, diluents, lubricants, glidants, flow enhancers, compression aids, coloring agents, sweeteners, preservatives, suspensing agents, dispersing agents, film formers, coatings, flavoring agents or printing inks.

40. The method of claim 1, wherein the packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents in administration form in response to at least one of the one or more parameters specifically associated with the individual comprises: packaging at least one of the one or more pharmaceutical agents in unit dosage form.

41. The method of claim 1, wherein the packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents in administration form in response to at least one of the one or more parameters specifically associated with the individual comprises: packaging at least one of the one or more pharmaceutical agents in oral administration form.

42. The method of claim 1, wherein the packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents in administration form in response to at least one of the one or more parameters specifically associated with the individual comprises: packaging at least one of the one or more pharmaceutical agents in parenteral administration form.

43. The method of claim 1, wherein the packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents in administration form in response to at least one of the one or more parameters specifically associated with the individual comprises: packaging at least one of the one or more pharmaceutical agents in transdermal administration form.

44. The method of claim 1 , wherein the packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents in administration form in response to at least one of the one or more parameters specifically associated with the individual comprises: packaging at least one of the one or more pharmaceutical agents in pulmonary administration form.

45. The method of claim 1, wherein the packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents in administration form in response to at least one of the one or more parameters specifically associated with the individual comprises: packaging at least one of the one or more pharmaceutical agents in depot administration form.

46. The method of claim 1, wherein the packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents in administration form in response to at least one of the one or more parameters specifically associated with the individual comprises: packaging at least one of the one or more pharmaceutical agents in response to a rapid release profile.

47. The method of claim 1, wherein the packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents in administration form in response to at least one of the one or more parameters specifically associated with the individual comprises: packaging at least one of the one or more pharmaceutical agents in response to specified release at one or more times.

48. The method of claim 1, wherein the packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents in administration form in response to at least one of the one or more parameters specifically associated with the individual comprises: packaging at least one of the one or more pharmaceutical agents in response to release over one or more time intervals.

49. The method of claim 1, wherein the packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents in administration form in response to at least one of the one or more parameters specifically associated with the individual comprises: packaging at least one of the one or more pharmaceutical agents in response to release at one or more sites specifically associated with the individual.

50. The method of claim 1, wherein the packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents in administration form in response to at least one of the one or more parameters specifically associated with the individual comprises: packaging at least one of the one or more pharmaceutical agents in response to a sustained release profile.

51. The method of claim 1, wherein the packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents in administration form in response to at least one of the one or more parameters specifically associated with the individual comprises: packaging at least one of the one or more pharmaceutical agents in storage material.

52. The method of claim 1, wherein the packaging at least one of the one or more pharmaceutical agents and at least one of the one or more niitraceutical agents in administration form in response to at least one of the one or more parameters specifically associated with the individual comprises: labeling at least one of the one or more pharmaceutical agents.

53. The method of claim 1, wherein the packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents in administration form in response to at least one of the one or more parameters specifically associated with the individual comprises: labeling storage material containing at least one of the one or more pharmaceutical agents'.

54. The method of claim 1, wherein the packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents in administration form in response to at least one of the one or more parameters specifically associated with the individual comprises: packaging at least one of the one or more nutraceutical agents with one or more pharmaceutically acceptable carriers or excipients.

55. The method of claim 1, wherein the packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents in administration form in response to at least one of the one or more parameters specifically associated with the individual comprises: packaging at least one of the one or more nutraceutical agents with one or more wrappers in administration form in response to at least one of the one or more parameters specifically associated with the individual.

56. The method of claim 1, wherein the packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents in administration form in response to at least one of the one or more parameters specifically associated with the individual comprises: packaging at least one of the one or more nutraceutical agents within two or more concentric wrappers in administration form in response to at least one of the one or more parameters specifically associated with the individual.

57. The method of claim 1, wherein the packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents in administration form in response to at least one of the one or more parameters specifically associated with the individual comprises: packaging at least one of the one or more nutraceutical agents within two or more nested capsules and/or two or more non-nested capsules in administration form in response to at least one of the one or more parameters specifically associated with the individual.

58. The method of claim 1, wherein the packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents in administration form in response to at least one of the one or more parameters specifically associated with the individual comprises: packaging at least one of the one or more nutraceutical agents within at least one tablet in administration form in response to at least one of the one or more parameters specifically associated with the individual.

59. The method of claim ] , wherein the packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents in administration form in response to at least one of the one or more parameters specifically associated with the individual comprises: packaging at least one of the one or more nutraceutical agents with one or more pharmaceutically acceptable poloxamers, humectants, binders, disintegrants, fillers, diluents, lubricants, glidants, flow enhancers, compression aids, coloring agents, sweeteners, preservatives, suspensing agents, dispersing agents, film formers, coatings, flavoring agents or printing inks.

60. The method of claim 1, wherein the packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents in administration form in response to at ieast one of the one or more parameters specifically associated with the individual comprises: packaging at least one of the one or more nutraceutical agents in unit dosage form.

61. The method of claim 1, wherein the packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents in administration form in response to at least one of the one or more parameters specifically associated with the individual comprises: packaging at least one of the one or more nutraceutical agents in- oral administration form.

62. The method of claim 1, wherein the packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents in administration form in response to at least one of the one or more parameters specifically associated with the individual comprises: packaging at least one of the one or more nittraceiitical agents in parenteral administration form.

63. The method of claim 1 , wherein the packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents in administration form in response to at least one of the one or more parameters specifically associated with the individual comprises: packaging at least one of the one or more nutraceutical agents in transdermal administration form.

64. The method of claim 1 , wherein the packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents in administration form in response to at least one of the one or more parameters specifically associated with the individual comprises: packaging at least one of the one or more nutraceutical agents in pulmonary administration form.

65. The method of claim 1 , wherein the packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents in administration form in response to at least one of the one or more parameters specifically associated with the individual comprises: packaging at least one of the one or more nutraceutical agents in depot administration form.

66. The method of claim 1 , wherein the packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents in administration form in response to at least one of the one or more parameters specifically associated with the individual comprises: packaging at least one of the one or more nutraceutical agents in response to a rapid release profile.

67. The method of claim 1 , wherein the packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents in administration foπii in response to at least one of the one or more parameters specifically associated with the individual comprises: packaging at least one of the one or more nutraceutical agents in response to specified release at one or more times.

68. The method of claim I, wherein the packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents in administration form in response to at least one of the one or more parameters specifically associated with the individual comprises: packaging at least one of the one or more nutraceutical agents in response to release over one or more time intervals,

69. The method of claim 1 , wherein the packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents in administration form in response to at least one of the one or more parameters specifically associated with the individual comprises: packaging at least one of the one or more nutraceutical agents in response to release at one or more sites specifically associated with the individual.

70. The method of claim 1 , wherein the packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents in administration form in response to at least one of the one or more parameters specifically associated with the individual comprises: packaging at least one of the one or more nutraceutical agents in response to a sustained release profile.

71. The method of claim 1, wherein the packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents in administration form in response to at least one of the one or more parameters specifically associated with the individual comprises: packaging at least one of the one or more nutraceutical agents in storage material.

72. The method of claim 1, wherein the packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents in administration form in response to at least one of the one or more parameters specifically associated with the individual comprises: labeling at least one of the one or more nutraceutical agents.

73. The method of claim 1, wherein the packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents in administration form in response to at least one of the one or more parameters specifically associated with the individual comprises: labeling storage material containing at least one of the one or more nutraceutical agents.

74. The method of claim I, wherein the packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nυtraceutical agents in administration form in response to at least one of the one or more parameters specifically associated with the individual comprises: packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents with one or more pharmaceutically acceptable carriers or excipients.

75. The method of claim 1, wherein the packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents in administration form in response to at least one of the one or more parameters specifically associated with the individual comprises: packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents with one or more wrappers in administration fbrm in response to at least one of the one or more parameters specifically associated with the individual.

76. The method of claim 1, wherein the packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents in administration form in response to at least one of the one or more parameters specifically associated with the individual comprises: packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents within two or more concentric wrappers in administration form in response to at least one of the one or more parameters specifically associated with the individual.

77. The method of claim I₃ wherein the packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents in administration form in response to at least one of the one or more parameters specifically associated with the individual comprises: packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents within two or more nested capsules and/or two or more non-nested capsules in administration form in response to at least one of the one or more parameters specifically associated with the individual.

78. The method of claim 1, wherein the packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents in administration form in response to at least one of the one or more parameters specifically associated with the individual comprises: packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents within at least one tablet in administration form in τesponse to at least one of the one or more parameters specifically associated with the individual.

79. The method of claim I, wherein the packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents in administration form in response to at least one of the one or more parameters specifically associated with the individual comprises: packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents in unit dosage form.

80. The method of claim 1 , wherein the packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents in administration form in response to at least one of the one or more parameters specifically associated with the individual comprises: packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents in ora! administration form.

81. The method of claim 1, wherein the packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents in administration foπn in response to at least one of the one or more parameters specifically associated with the individual comprises: packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents in response to a sustained release profile.

82. The method of claim 1, wherein the packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents in administration form in response to at least one of the one or more parameters specifically associated with the individual comprises: packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents in storage material.

83. The method of claim 1, wherein the packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents in administration form in response to at least one of the one or more parameters specifically associated with the individual comprises: labeling at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents.

84. The method of claim 1 , wherein the packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents in administration form in response to at least one of the one or more parameters specifically associated with the individual comprises: labeling storage material containing at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents.

85. A system comprising: circuitry for accepting input of one or more parameters specifically associated • with an individual,- circuitry for selecting one or more pharmaceutical agents in response to at least one of the one or more parameters specifically associated with the individual; circuitry for selecting one or more nutraceutical agents in response to at least one of the one or more parameters specifically associated with the individual; and circuitry for packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents in administration form in response to at least one of the one or more parameters specifically associated with the individual.

86. The system of claim 85, wherein the circuitry for accepting input of one or more parameters specifically associated with an individual comprises: circuitry for accepting the one or more parameters specifically associated with a human individual.

87. The system of claim 85, wherein the circuitry for accepting input of one or more parameters specifically associated with an individual comprises: circuitry for accepting the one or more parameters specifically associated with non-human individual.

88. The system of claim 85, wherein the circuitry for accepting input of one or more parameters specifically associated with an individual comprises: circuitry for accepting the one or more parameters specifically associated with a physician input.

89. The system of claim 85, wherein the circuitry for accepting input of one or more parameters specifically associated with an individual comprises: circuitry for accepting the one or more parameters specifically associated with a veterinarian input.

90. The system of claim 85, wherein the circuitry for accepting input of one or more parameters specifically associated with an individual comprises: circuitry for accepting the one or more parameters specifically associated with a pharmacist input.

91. The system of claim 85, wherein the circuitry for accepting input of one or more parameters specifically associated with an individual comprises: circuitry for accepting the one or more parameters specifically associated with a patient input.

92. The system of claim 85, wherein the circuitry for accepting input of one or more parameters specifically associated with an individual comprises: circuitry for accepting the one or more parameters specifically associated with a machine input.

93. The system of claim 85, wherein the circuitry for accepting input of one or more parameters specifically associated with an individual comprises: circuitry for accepting the one or more parameters associated with at least one of a nutritionist input, a regimen subscription input, a regimen specification input, a recommending party input, a recommending entity input, an advising party input, or an advising entity input.

94. The system of claim 85, wherein the circuitry for selecting one or more pharmaceutical agents in response to at least one of the one or more parameters specifically associated with the individual comprises: circuitry for selecting at least one of the one or more pharmaceutical agents in response to the selecting one or more nutraceutical agents in response to at least one of the one or more parameters specifically associated with the individual.

95. The system of claim 85, wherein the circuitry for selecting one or more pharmaceutical agents in response to at least one of the one or more parameters specifically associated with the individual comprises: circuitry for selecting at least one of the one or more pharmaceutical agents in response to at least one condition specifically associated with the individual.

96. The system of claim 95, wherein the circuitry for selecting one or more pharmaceutical agents in response to at least one of the one or more parameters specifically associated with the individual comprises: circuitry for selecting at least one of the two or more pharmaceutical agents in response to at least one condition specifically associated with the individual wherein the at least one condition includes at least one of attentiveness, alertness, test performance, relaxation, pain, fever, anxiety, fall, injury, accident, bite, bleeding, inflammation, infection, drowsiness, insomnia, discomfort, stress, grooming, appearance, capability, performance, improvement, enhancement, curtailment, wellbeing, vitality, vigor, disability, phobia, malady, psychosis, environmental extremes, environmental exposure, dysfunction, disease symptom, chronic condition, mental acuity, emotional behavior, physical prowess, addiction, obsession, therapy, remedy, behavior, nutrition, diet, exercise, immunization, prevention, diagnosis, or treatment.

97. The system of claim 85, wherein the circuitry for selecting one or more pharmaceutical agents in response to at least one of the one or more parameters specifically associated with the individual comprises: circuitry for selecting at least one of the one or more pharmaceutical agents in response to at least one dosage specifically associated with the individual.

98. The system of claim 85, wherein the circuitry for selecting one or more pharmaceutical agents in response to at least one of the one or more parameters specifically associated with the individual comprises: circuitry for selecting at least one of the one or more pharmaceutical agents in response to dosage of at least one of the one or more pharmaceutical agents.

99. The system of claim 85, wherein the circuitry for selecting one or more pharmaceutical agents in response to at least one of the one or more parameters specifically associated with the individual comprises: circuitry for selecting at least one of the one or more pharmaceutical agents in response to at least one time of administration.

100. The system of claim 85, wherein the circuitry for selecting one or more pharmaceutical agents in response to at least one of the one or more parameters specifically associated with the individual comprises: circuitry for selecting at least one of the one or more pharmaceutical agents in response to two or more times of administration within a time period.

101. The system of claim 85, wherein the circuitry for selecting one or more pharmaceutical agents in response to at least one of the one or more parameters specifically associated with the individual comprises: circuitry for selecting at least one of the one or more pharmaceutical agents in response to one or more sites of administration specifically associated with the individual.

102. The system of claim 85, wherein the circuitry for selecting one or more pharmaceutical agents in response to at least one of the one or more pai-ameters specifically associated with the individual comprises: circuitry for selecting at least one of the one or more pharmaceutical agents in response to one or more sites of release specifically associated with the individual.

103. The system of claim 85, wherein the circuitry for selecting one or more pharmaceutical agents in response to at least one of the one or more parameters specifically associated with the individual comprises: circuitry for selecting at least one of the one or more pharmaceutical agents in response to one or more physiological characteristics specifically associated with the individual.

104. The system of claim 85, wherein the circuitry for selecting one or more pharmaceutical agents in response to at least one of the one or more parameters specifically associated with the individual comprises: circuitry for selecting at least one of the one or more pharmaceutical agents in response to cost associated with at least one of the one or more pharmaceutical agents.

105. The system of claim 85, wherein the circuitry for selecting one or more pharmaceutical agents in response to at least one of the one or more parameters specifically associated with the individual comprises: circuitry for selecting at least one of the one or more pharmaceutical agents in response to compatibility of at least one of the pharmaceutical agents with another of the one or more pharmaceutical agents.

106. The system of claim 85, wherein the circuitry for selecting one or more nutraceutical agents in response to at least one of the one or mo_-e parameters specifically associated with the individual comprises: circuitry for selecting at least one of the one or more nutraceutical agents in response to the selecting one or more pharmaceutical agents in response to at least one of the one or more parameters specifically associated with the individual.

107. The system of claim 85, wherein the circuitry for selecting one or more nutraceutical agents in response to at least one of the one or more parameters specifically associated with the individual comprises: circuitry for selecting at least one of the one or more nutraceutical agents in response to at least one condition specifically associated with the individual.

108. The system of claim 85, wherein the circuitry for selecting one or more nutraceutical agents in response to at least one of the one or more parameters specifically associated with the individual comprises: circuitry for selecting at least one of the two or more nutraceυtical agents in response to at least one condition specifically associated with the individual wherein the at least one condition includes at least one of attentiveness, alertness, test performance, relaxation, pain, fever, anxiety, fall, injury, accident, bite, bleeding, inflammation, infection, drowsiness, insomnia, discomfort, stress, grooming, appearance, capability, performance, improvement, enhancement, curtailment, wellbeing, vitality, vigor, disability, phobia, malady, psychosis, environmental extremes, environmental exposure, dysfunction, disease symptom, chronic condition, mental acuity, emotional behavior, physical prowess, addiction, obsession, therapy, remedy, behavior, nutrition, diet, exercise, immunization, prevention, diagnosis, subscription, regimen, goal to be achieved, or treatment.

109. The system of claim 85, wherein the circuitry for selecting one or more nutraceutical agents in response to at least one of the one or more parameters specifically associated with the individual comprises: circuitry for selecting at least one of the one or more nutraceutical agents in response to at least one dosage specifically associated with the individual.

1 10. The system of claim 85, wherein the circuitry for selecting one or more nutraceutical agents in response to at least one of the one or more parameters specifically associated with the individual comprises: circuitry for selecting at least one of the one or more nutraceutical agents in response to dosage of at least one of the one or more nutraceutical agents.

1 1 1. The system of claim 85, wherein the circuitry for selecting one or more nutraceutical agents in response to at least one of the one or more parameters specifically associated with the individual comprises: circuitry for selecting at least one of the one or more nutraceutica] agents in response to at least one time of administration.

1 12. The system of claim 85, wherein the circuitry for selecting one or more nutraceutical agents in response to at least one of the one or more parameters specifically associated with the individual comprises: circuitry for selecting at least one of the one or more nutraceutical agents in response to two or more times of administration within a time period.

1 13. The system of claim 85, wherein the circuitry for selecting one or more nutraceutical agents in response to at least one of the one or more parameters specifically associated with the individual comprises: circuitry for selecting at least one of the one or more nutraceutical agents in response to one or more sites of administration specifically associated with the individual.

1 14. The system of claim 85, wherein the circuitry for selecting one or more nutraceutical agents in response to at least one of the one or more parameters specifically associated with the individual comprises: selecting at least one of the one or more nutraceutical agents in response to one or more sites of release specifically associated with the individual.

1 15. The system of claim 85, wherein the circuitry for selecting one or more nutraceutical agents in response to at least one of the one or more parameters specifically associated with the individual comprises: circuitry for selecting at least one of the one or more nutraceutical agents in response to one or more physiological characteristics specifically associated with the individual.

1 16. The system of claim 85, wherein the circuitry for selecting one or more nutraceutical agents in response to at least one of the one or more parameters specifically associated with the individual comprises: circuitry for selecting at least one of the one or more nutraceutical agents in response to cost associated with at least one of the one or more nutraceutical agents.

117. The system of claim 85, wherein the circuitry for selecting one or more nutraceutical agents in response to at least one of the one or more parameters specifically associated with the individual comprises: circuitry for selecting at least one of the one or more nutraceutical agents in response to compatibility of at least one of the nutraceutical agents with another of the one or more nutraceutical agents.

118. The system of claim 85, wherein the circuitry for packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents in administration form in response to at least one of the one or more parameters specifically associated with the individual comprises: circuitry for packaging at least one of the one or more pharmaceutical agents with one or more pharmaceutically acceptable carriers or excipients.

1 19. The system of claim 85, wherein the circuitry for packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents in administration form in response to at least one of the one or more parameters specifically associated with the individual comprises: circuitry for packaging at least one of the one or more pharmaceutical agents with one or more wrappers in administration form in response to at least one of the one or more parameters specifically associated with the individual.

120. The system of claim 85, wherein the circuitry for packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents in administration form in response to at least one of the one or more parameters specifically associated with the individual comprises: circuitry for packaging at least one of the one or more pharmaceutical agents within two or more concentric wrappers in administration form in response to at least one of the one or more parameters specifically associated with the individual.

121. The system of claim 85, wherein the circuitry for packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents in administration form in response to at least one of the one or more parameters specifically associated with the individual comprises: circuitry for packaging at least one of the one or more pharmaceutical agents within two or more nested capsules and/or two or more non-nested capsules in administration form in response to at least one of the one or more parameters specifically associated with the individual.

122. The system of claim 85, wherein the circuitry for packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents in administration form in response to at least one of the one or more parameters specifically associated with the individual comprises: circuitry for packaging at least one of the one or more pharmaceutical agents within at least one tablet in administration form in response to at least one of the one or more parameters specifically associated with the individual.

123. The system of claim 85, wherein the circuitry for packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceuticaJ agents in administration form in response to at least one of the one or more parameters specifically associated with the individual comprises: circuitry for packaging at least one of the one or more pharmaceutical agents with one or more pharmaceutically acceptable poloxamers, humectants, binders, disintegrants, fillers, diluents, lubricants, glidants, flow enhancers, compression aids, coloring agents, sweeteners, preservatives, suspensiπg agents, dispersing agents, film formers, coatings, flavoring agents or printing inks.

124. The system of claim 85, wherein the circuitry for packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents in administration form in response to at least one of the one or more parameters specifically associated with the individual comprises: circuitry for packaging at least one of the one or more pharmaceutical agents in unit dosage form.

125. The system of claim 85, wherein the circuitry for packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents in administration form in response to at least one of the one or more parameters specifically associated with the individual comprises: circuitry for packaging at least one of the one or more pharmaceutical agents in oral administration form.

126. The system of claim 85, wherein the circuitry for packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents in administration form in response to at least one of the one or more parameters specifically associated with the individual comprises: circuitry for packaging at least one of the one or more pharmaceutical agents in parenteral administration form.

127. The system of claim 85, wherein the circuitry for packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents in administration form in response to at least one of the one or more parameters specifically associated with the individual comprises: circuitry for packaging at least one of the one or more pharmaceutical agents in transdermal administration form.

128. The system of claim 85, wherein the circuitry for packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents in administration form in response to at least one of the one^' or more parameters specifically associated with the individual comprises: circuitry for packaging at least one of the one or more pharmaceutical agents in pulmonary administration form.

129. The system of claim 85, wherein the circuitry for packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents in administration form in response to at least one of the one or more parameters specifically associated with the individual comprises: circuitry for packaging at least one of the one or more pharmaceutical agents in depot administration form.

130. The system of claim 85, wherein the circuitry for packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents in administration form in response to at least one of the one or more parameters specifically associated with the individual comprises: circuitry for packaging at least one of the one or more pharmaceutical agents in response to a rapid release profile.

131. The system of claim 85, wherein the circuitry for packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents in administration form in response to at least one of the one or more parameters specifically associated with the individual comprises: circuitry for packaging at least one of the one or more pharmaceutical agents in response to specified release at one or more times.

132. The system of claim 85, wherein the circuitry for packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents in administration form in response to at least one of the one or more parameters specifically associated with the individual comprises: circuitry for packaging at least one of the one or more pharmaceutical agents in response to release over one or more time intervals.

133. The system of claim 85, wherein the circuitry for packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents in administration form in response to at [east one of the one or more parameters specifically associated with the individual comprises: circuitry for packaging at least one of the one or more pharmaceutical agents in response to release at one or more sites specifically associated with the individual.

134. The system of claim 85, wherein the circuitry for packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents in administration form in response to at least one of the one or more parameters specifically associated with the individual comprises: circuitry for packaging at least one of the one or more pharmaceutical agents in response to a sustained release profile.

135. The system of claim 85, wherein the circuitry for packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents in administration form in response to at least one of the one or more parameters specifically associated with the individual comprises: circuitry for packaging at least one of the one or more pharmaceutical agents in storage material.

136. The system of claim 85, wherein the circuitry for packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents in administration form in response to at least one of the one or more parameters specifically associated with the individual comprises: circuitry for labeling at least one of the one or more pharmaceutical agents.

137. The system of claim 85, wherein the circuitry for packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents in administration form in response to at least one of the one or more parameters specifically associated with the individual comprises: circuitry for labeling storage material containing at least one of the one or more pharmaceutical agents.

138. The system of claim 85, wherein the circuitry for packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents in administration form in response to at least one of the one or more parameters specifically associated with the individual comprises: circuitry for packaging at least one of the one or more nutraceutical agents with one or more pharmaceutically acceptable earners or excipients.

139. The system of claim 85, wherein the circuitry for packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents in administration form in response to at least one of the one or more parameters specifically associated with the individual comprises: circuitry for packaging at least one of the one or more nutraceutical agents with one or more wrappers in administration form in response to at least one of the one or more parameters specifically associated with the individual.

140. The system of claim 85, wherein the circuitry for packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents in administration form in response to at least one of the one or more parameters specifically associated with the individual comprises: circuitry for packaging at least one of the one or more nutraceutical agents within two or more concentric wrappers in administration form in response to at least one of the one or more parameters specifically associated with the individual.

141. The system of claim 85, wherein the circuitry for packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents in administration form in response to at least one of the one or more parameters specifically associated with the individual comprises: circuitry for packaging at least one of the one or more nutraceutical agents within two or more nested capsules and/or two or more non-nested capsules in administration form in response to at least one of the one or more parameters specifically associated with the individual.

142. The system of claim 85, wherein the circuitry for packaging at least one of the one or more pharmaceutical agents and at Least one of the one or more nutraceutical agents in administration form in response to at least one of the one or more parameters specifically associated with the individual comprises: circuitry for packaging at least one of the .one or more nutraceutical agents within at least one tablet in administration form in response to at least one of the one or more parameters specifically associated with the individual.

143. The system of claim 85, wherein the circuitry for packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents in administration form in response to at least one of the one or more parameters specifically associated with the individual comprises: circuitry for packaging at least one of the one or more nutraceutical agents with one or more pharmaceutically acceptable poloxamers, humectants, binders, disintegrants, fillers, diluents, lubricants, glidants, flow enhancers, compression aids, coloring agents, sweeteners, preservatives, suspensing agents, dispersing agents, film formers, coatings, flavoring agents, or printing inks.

144. The system of claim 85, wherein the circuitry for packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents in administration form in response to at least one of the one or more parameters specifically associated with the individual comprises: circuitry for packaging at least one of the one or more nutraceutical agents in unit dosage form.

145. The system of claim 85, wherein the circuitry for packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents in administration form in response to at least one of the one or more parameters specifically associated with the individual comprises: circuitry for packaging at least one of the one or more nutraceutical agents in oral administration form.

146. The system of claim 85, wherein the circuitry for packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents in administration form in response to at least one of the one or more parameters specifically associated with the individual comprises: circuitry for packaging at least one of the one or more nutraceutical agents in parenteral administration form.

147. The system of claim 85, wherein the circuitry for packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents in administration form in response to at least one of the one or more parameters specifically associated with the individual comprises: circuitry for packaging at least one of the one or more nutraceutical agents in transdermal administration form.

148. The system of claim 85, wherein the circuitry for packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents in administration form in response to at least one of the one or moi^{^}e parameters specifically associated with the individual comprises: circuitry for packaging at least one of the one or more nutraceutical agents in pulmonary administration form.

149. The system of claim 85, wherein the circuitry for packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceυtical agents in administration form in response to at least one of the one or more parameters specifically associated with the individual comprises: ciz'cuitry for packaging at least one of the one or more nutraceutical agents in depot administration form.

150. The system of claim 85, wherein the circuitry for packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents in administration form in response to at least one of the one or more parameters specifically associated with the individual comprises: circuitry for packaging at least one of the one or more nutraceutical agents in response to a rapid release profile.

151. The system of claim 85, wherein the circuitry for packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents in administration form in response to at least one of the one or more parameters specifically associated with the individual comprises: circuitry for packaging at least one of the one or more nutraceutical agents in response to specified release at one or more times.

152. The system of claim 85, wherein the circuitry for packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents in administration form in response to at least one of the one or more parameters specifically associated with the individual comprises: circuitry for packaging at least one of the one or more nutraceutical agents in response to release over one or more time intervals.

153. The system of claim 85, wherein the circuitry for packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents in administration form in response to at least one of the one or more parameters specifically associated with the individual comprises: circuitry for packaging at least one of the one or more nutraceutical agents in response to release at one or more sites specifically associated with the individual.

154. The system of claim 85, wherein the circuitry for packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents in administration form in response to at least one of the one or more parameters specifically associated with the individual comprises: circuitry for packaging at least one of the one or more nutraceutical agents in response to a sustained release profile.

155. The system of claim 85, wherein the circuitry for packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents in administration form in response to at least one of the one or more parameters specifically associated with the individual comprises: circuitry for packaging at least one of the one or more nutraceutical agents in storage material.

156. The system of claim 85, wherein the circuitry for packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents in administration form in response to at least one of the one or more parameters specifically associated with the individual comprises: circuitry for labeling at least one of the one or more nutraceutical agents.

157. The system of claim 85, wherein the circuitry for packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents in administration form in response to at least one of the one or more parameters specifically associated with the individual comprises: circuitry for labeling storage material containing at least one of the one or more nutraceutical agents.

158. The system of claim 85, wherein the circuitry for packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents in administration form in response to at least one of the one or more parameters specifically associated with the individual comprises: circuitry for packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents with one or more pharmaceutically acceptable carriers or excipients.

159. The system of claim 85, wherein the circuitry for packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents in administration form in response to at least one of the one or more parameters specifically associated with the individual comprises: circuitry for packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents with one or more wrappers in administration form in response to at least one of the one or more parameters specifically associated with the individual.

160. The system of claim 85, wherein the circuitry for packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents in administration form in response to at least one of the one or more parameters specifically associated with the individual comprises: circuitry for packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents within two or more concentric wrappers in administration form in response to at least one of the one or more parameters specifically associated with the individual.

161. The system of claim 85, wherein the circuitry for packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents in administration form in response to at least one of the one or more parameters specifically associated with the individual comprises: circuitry for packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents within two or more nested capsules and/or two or more non-nested capsules in administration form in response to at least one of the one or more parameters specifically associated with the individual.

162. The system of claim 85, wherein the circuitry for packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents in administration form in response to at least one of the one or more parameters specifically associated with the individual comprises: circuitry for packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents within at least one tablet in administration form in response to at least one of the one or more parameters specifically associated with the individual.

163. The system of claim 85, wherein the circuitry for packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents in administration form in response to at least one of the one or more parameters specifically associated with the individual comprises: circuitry for packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents in unit dosage form.

164. The system of claim 85, wherein the circuitry for packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents in administration form in response to at least one of the one or more parameters specifically associated with the individual comprises: circuitry for packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents in oral administration form.

165. The system of claim 85, wherein the circuitry for packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents in administration form in response to at least one of the one or more parameters specifically associated with the individual comprises: circuitry for packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents in response to a sustained release profile.

166. The system of claim 85, wherein the circuitry for packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents in administration form in response to at least one of the one or more parameters specifically associated with the individual comprises: circuitry for packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents in storage material.

167. The system of claim 85, wherein the circuitry for packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents in administration form in response to at least one of the one or more parameters specifically associated with the individual comprises: circuitry for labeling at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents.

168. The system of claim 85, wherein the circuitry for packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents in administration form in response to at least one of the one or more parameters specifically associated with the individual comprises: circuitry for labeling storage material containing at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents.

169. A system comprising: means for accepting input of one or more parameters specifically associated with an individual; means for selecting one or more pharmaceutical agents in response to at least one of the one or more paz-ameters specifically associated with the individual; means for selecting one or more nutraceutical agents in response to at least one of the one or more parameters specifically associated with the individual; and means for packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents in administration form in response to at least one of the one or more parameters specifically associated with the individual.

170. A system comprising: a signal-bearing medium bearing at least one of: one or more instructions for accepting input of one or more parameters specifically associated with an individual; one or more instructions for selecting one or more pharmaceutical agents in response to at least one of the one or more parameters specifically associated with the individual; one or more instructions for selecting one or more nutraceutical agents in response to at least one of the one or more parameters specifically associated with the individual; and one or more instructions for packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents in administration form in response to at least one of the one .or more parameters specifically associated with the individual.

171. The system of claim 170, wherein the signal-bearing medium includes a computer- readable medium.

172. The system of claim 170, wherein the signal-bearing medium includes a recordable medium.

173. The system of claim 170, wherein the signal-bearing medium includes a communications medium.

174. A method comprising: accepting input of one or more parameters associated with an individual; selecting one or more pharmaceutical agents in response to at least one of the one or more parameters associated with the individual; selecting one or more nutraceutical agents in response to at least one of the one or more parameters associated with the individual; and packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents in administration form in response to at least one of the one or more parameters associated with the individual.

175. A system comprising: circuitry for accepting input of one or more parameters associated with an individual; circuitry for selecting one or more pharmaceutical agents in response to at least one of the one or more parameters associated with the individual; circuitry for selecting one or more nutraceutical agents in response to at least one of the one or more parameters associated with the individual; and circuitry for packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents in administration form in response to at least one of the one or more parameters associated with the individual.

176. A system comprising: means for accepting input of one or more parameters associated with an individual; means for selecting one or more pharmaceutical agents in response to at least one of the one or more parameters associated with the individual; means for selecting one or more nutraceutical agents in response to at least one of the one or more parameters associated with the individual; and means for packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents in administration form in response to at least one of the one or more parameters associated with the individual.

177. A system comprising: a signal-bearing medium bearing at least one of: one or more instructions for accepting input of one or more parameters associated with an individual; one or more instructions for selecting one or more pharmaceutical agents in response to at least one of the one or more parameters associated with the individual; one or more instructions for selecting one or more nutraceutical agents in response to at least one of the one or more parameters associated with the individual; and one or more instructions for packaging at least one of the one or more pharmaceutical agents and at least one of the one or more nutraceutical agents in administration form in response to at least one of the one or more parameters associated with the individual.