WO2007076524A3 - Human anti-il-23 antibodies, compositions, methods and uses - Google Patents
Human anti-il-23 antibodies, compositions, methods and uses Download PDFInfo
- Publication number
- WO2007076524A3 WO2007076524A3 PCT/US2006/062674 US2006062674W WO2007076524A3 WO 2007076524 A3 WO2007076524 A3 WO 2007076524A3 US 2006062674 W US2006062674 W US 2006062674W WO 2007076524 A3 WO2007076524 A3 WO 2007076524A3
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/244—Interleukins [IL]
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K9/08—Solutions
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/42—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/10—Cells modified by introduction of foreign genetic material
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/566—Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds
- G01N33/567—Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds utilising isolate of tissue or organ as binding agent
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/52—Constant or Fc region; Isotype
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/55—Fab or Fab'
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
Abstract
Priority Applications (33)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN2006800535467A CN101389351B (en) | 2005-12-29 | 2006-12-28 | Human anti-il-23 antibodies, compositions, methods and uses |
PL17156111T PL3219328T3 (en) | 2005-12-29 | 2006-12-28 | Human anti-il-23 antibodies, compositions, method and uses |
BRPI0620946A BRPI0620946B8 (en) | 2005-12-29 | 2006-12-28 | isolated il-23p19 antibody, composition, in vitro method, article of manufacture, nucleic acid molecule and vector, prokaryotic host cell |
SI200631828T SI1971366T1 (en) | 2005-12-29 | 2006-12-28 | Human anti-il-23 antibodies, compositions, methods and uses |
AU2006330411A AU2006330411B2 (en) | 2005-12-29 | 2006-12-28 | Human anti-IL-23 antibodies, compositions, methods and uses |
NZ569546A NZ569546A (en) | 2005-12-29 | 2006-12-28 | Human anti-IL-23 antibodies, compositions, methods and uses |
EP06846836.2A EP1971366B1 (en) | 2005-12-29 | 2006-12-28 | Human anti-il-23 antibodies, compositions, methods and uses |
PL06846836T PL1971366T3 (en) | 2005-12-29 | 2006-12-28 | Human anti-il-23 antibodies, compositions, methods and uses |
JP2008548853A JP5193881B2 (en) | 2005-12-29 | 2006-12-28 | Human anti-IL-23 antibodies, compositions, methods and uses |
MX2008008621A MX2008008621A (en) | 2005-12-29 | 2006-12-28 | Human anti-il-23 antibodies, compositions, methods and uses. |
CA2635692A CA2635692C (en) | 2005-12-29 | 2006-12-28 | Human anti-il-23 antibodies, compositions, methods and uses |
RS20140565A RS53685B1 (en) | 2005-12-29 | 2006-12-28 | Human anti-il-23 antibodies, compositions, methods and uses |
EP17156111.1A EP3219328B1 (en) | 2005-12-29 | 2006-12-28 | Human anti-il-23 antibodies, compositions, method and uses |
DK06846836.2T DK1971366T3 (en) | 2005-12-29 | 2006-12-28 | Human anti-IL-23 antibodies, compositions, methods and applications |
EA200870129A EA019476B9 (en) | 2005-12-29 | 2006-12-28 | ANTI-IL-23p19 ANTIBODIES AND USE THEREOF |
ES06846836.2T ES2517420T3 (en) | 2005-12-29 | 2006-12-28 | Human anti-IL-23 antibodies, compositions, procedures and uses |
EP20180279.0A EP3760230A1 (en) | 2005-12-29 | 2006-12-28 | Human anti-il-23 antibodies, compositions, methods and uses |
UAA200809846A UA101301C2 (en) | 2005-12-29 | 2006-12-28 | Isolated il-23pl9 antibody and use thereof |
IL192458A IL192458A (en) | 2005-12-29 | 2008-06-26 | Iil-23p19 antibodies, compositions and articles comprising them and uses thereof |
NO20083266A NO343345B1 (en) | 2005-12-29 | 2008-07-23 | Human anti-IL-23 antibodies, compositions, methods and uses thereof |
HK09102604.5A HK1124548A1 (en) | 2005-12-29 | 2009-03-18 | Human anti-il-23 antibodies, compositions, methods and uses il-23 |
IL219890A IL219890A (en) | 2005-12-29 | 2012-05-20 | Anti-idiotype antibodies binding to il-23p19 antibodies |
HRP20140982TT HRP20140982T1 (en) | 2005-12-29 | 2014-10-14 | Human anti-il-23 antibodies, compositions, methods and uses |
IL236427A IL236427A (en) | 2005-12-29 | 2014-12-24 | Isolated nucleic acids, vectors, host cells and methods of producing il-23p19 antibodies |
IL248917A IL248917A0 (en) | 2005-12-29 | 2016-11-13 | Human anti-il-23 antibodies,compositions, methods and uses |
IL258718A IL258718A (en) | 2005-12-29 | 2018-04-16 | Human anti-il-23 antibodies,compositions, methods and uses |
NL300935C NL300935I2 (en) | 2005-12-29 | 2018-04-26 | guselkumab. |
CY2018013C CY2018013I1 (en) | 2005-12-29 | 2018-05-07 | HUMAN ANTI-IL-23 ANTIBODIES, COMPOSITIONS, METHODS AND USES |
LTPA2018010C LTC1971366I2 (en) | 2005-12-29 | 2018-05-08 | Human anti-IL-23 antibodies, compositions, methods, and uses |
NO20190011A NO344118B1 (en) | 2005-12-29 | 2019-01-04 | Human anti-IL-23 antibodies, compositions, in vitro methods and uses thereof, as well as nucleic acid molecules, vectors and host cells, and medical device and article. |
NO2019029C NO2019029I1 (en) | 2005-12-29 | 2019-07-10 | Guselkumab, see cover letter for further explanation |
NO20190992A NO20190992A1 (en) | 2005-12-29 | 2019-08-16 | Human anti-IL-23 antibodies, compositions, methods and uses |
CY20201100813T CY1123400T1 (en) | 2005-12-29 | 2020-08-31 | HUMAN ANTI-IL-23 ANTIBODIES, COMPOSITIONS, METHODS AND USES |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US75488905P | 2005-12-29 | 2005-12-29 | |
US60/754,889 | 2005-12-29 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2007076524A2 WO2007076524A2 (en) | 2007-07-05 |
WO2007076524A3 true WO2007076524A3 (en) | 2008-03-27 |
Family
ID=38218878
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2006/062674 WO2007076524A2 (en) | 2005-12-29 | 2006-12-28 | Human anti-il-23 antibodies, compositions, methods and uses |
Country Status (37)
Country | Link |
---|---|
US (9) | US7935344B2 (en) |
EP (4) | EP3760230A1 (en) |
JP (1) | JP5193881B2 (en) |
KR (1) | KR101210395B1 (en) |
CN (2) | CN102887954B (en) |
AU (1) | AU2006330411B2 (en) |
BR (1) | BRPI0620946B8 (en) |
CA (1) | CA2635692C (en) |
CR (1) | CR10181A (en) |
CY (4) | CY1115935T1 (en) |
DK (3) | DK2548577T3 (en) |
EA (2) | EA035459B1 (en) |
EC (1) | ECSP088591A (en) |
ES (3) | ES2517420T3 (en) |
GT (1) | GT200800132A (en) |
HK (1) | HK1124548A1 (en) |
HN (1) | HN2008000988A (en) |
HR (3) | HRP20140982T1 (en) |
HU (3) | HUE034269T2 (en) |
IL (5) | IL192458A (en) |
LT (3) | LT3219328T (en) |
LU (1) | LUC00071I2 (en) |
MX (2) | MX2008008621A (en) |
MY (2) | MY162559A (en) |
NI (1) | NI200800193A (en) |
NL (1) | NL300935I2 (en) |
NO (4) | NO343345B1 (en) |
NZ (1) | NZ569546A (en) |
PL (3) | PL2548577T3 (en) |
PT (3) | PT3219328T (en) |
RS (3) | RS53685B1 (en) |
SG (1) | SG10201505755YA (en) |
SI (3) | SI3219328T1 (en) |
SV (1) | SV2008002972A (en) |
UA (1) | UA101301C2 (en) |
WO (1) | WO2007076524A2 (en) |
ZA (1) | ZA200806556B (en) |
Families Citing this family (105)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7090847B1 (en) | 1999-09-09 | 2006-08-15 | Schering Corporation | Mammalian cytokines; related reagents and methods |
AU2006265002B2 (en) | 2005-06-30 | 2012-09-20 | Centocor, Inc. | Anti-IL-23 antibodies, compositions, methods and uses |
ATE475672T1 (en) * | 2005-08-25 | 2010-08-15 | Lilly Co Eli | ANTI-IL-23 ANTIBODIES |
RS55788B1 (en) | 2005-08-31 | 2017-08-31 | Merck Sharp & Dohme | Engineered anti-il-23 antibodies |
CA2621086A1 (en) | 2005-09-01 | 2007-03-08 | Schering Corporation | Use of il-23 and il-17 antagonists to treat autoimmune ocular inflammatory disease |
EA035459B1 (en) | 2005-12-29 | 2020-06-19 | Сентокор, Инк. | ANTI-IL-23p19 ANTIBODY |
US7910703B2 (en) | 2006-03-10 | 2011-03-22 | Zymogenetics, Inc. | Antagonists to IL-17A, IL-17F, and IL-23P19 and methods of use |
CA2655372A1 (en) | 2006-06-13 | 2007-12-21 | Zymogenetics, Inc. | Il-17 and il-23 antagonists and methods of using the same |
TWI426918B (en) | 2007-02-12 | 2014-02-21 | Merck Sharp & Dohme | Use of il-23 antagonists for treatment of infection |
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