WO2007092929A3 - Apparatus and methods for delivering fluid and material to a subject - Google Patents

Apparatus and methods for delivering fluid and material to a subject Download PDF

Info

Publication number
WO2007092929A3
WO2007092929A3 PCT/US2007/061856 US2007061856W WO2007092929A3 WO 2007092929 A3 WO2007092929 A3 WO 2007092929A3 US 2007061856 W US2007061856 W US 2007061856W WO 2007092929 A3 WO2007092929 A3 WO 2007092929A3
Authority
WO
WIPO (PCT)
Prior art keywords
subject
cellular material
methods
needle
injected
Prior art date
Application number
PCT/US2007/061856
Other languages
French (fr)
Other versions
WO2007092929A2 (en
Inventor
Terrell Pruitt
Stephen A Cochran
Bryan Marshall
Yandong Su
Kurt Stricker Stenn
Kenneth Justin Washenik
John Depiano
Gary F Prokop
Martin Rathgeber
Original Assignee
Aderans Res Inst Inc
Terrell Pruitt
Stephen A Cochran
Bryan Marshall
Yandong Su
Kurt Stricker Stenn
Kenneth Justin Washenik
John Depiano
Gary F Prokop
Martin Rathgeber
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aderans Res Inst Inc, Terrell Pruitt, Stephen A Cochran, Bryan Marshall, Yandong Su, Kurt Stricker Stenn, Kenneth Justin Washenik, John Depiano, Gary F Prokop, Martin Rathgeber filed Critical Aderans Res Inst Inc
Priority to CA2642129A priority Critical patent/CA2642129C/en
Priority to CA2779561A priority patent/CA2779561A1/en
Priority to MX2008010258A priority patent/MX2008010258A/en
Priority to EP07763663A priority patent/EP1986731A4/en
Priority to JP2008554503A priority patent/JP4910002B2/en
Priority to CN2007800109676A priority patent/CN101421002B/en
Priority to AU2007213706A priority patent/AU2007213706B2/en
Publication of WO2007092929A2 publication Critical patent/WO2007092929A2/en
Publication of WO2007092929A3 publication Critical patent/WO2007092929A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31576—Constructional features or modes of drive mechanisms for piston rods
    • A61M5/31583—Constructional features or modes of drive mechanisms for piston rods based on rotational translation, i.e. movement of piston rod is caused by relative rotation between the user activated actuator and the piston rod
    • A61M5/31586—Constructional features or modes of drive mechanisms for piston rods based on rotational translation, i.e. movement of piston rod is caused by relative rotation between the user activated actuator and the piston rod performed by rotationally moving or pivoted actuator, e.g. an injection lever or handle
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • A61M2005/2403—Ampoule inserted into the ampoule holder
    • A61M2005/2411—Ampoule inserted into the ampoule holder from the front
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • A61M2005/2403—Ampoule inserted into the ampoule holder
    • A61M2005/2414—Ampoule inserted into the ampoule holder from the side
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/34—Constructions for connecting the needle, e.g. to syringe nozzle or needle hub
    • A61M2005/341—Constructions for connecting the needle, e.g. to syringe nozzle or needle hub angularly adjustable or angled away from the axis of the injector
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/34—Constructions for connecting the needle, e.g. to syringe nozzle or needle hub
    • A61M2005/342—Off-center needles, i.e. needle connections not being coaxial with the longitudinal symmetry axis of syringe barrel
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/3148—Means for causing or aiding aspiration or plunger retraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533—Dosing mechanisms, i.e. setting a dose
    • A61M5/31545—Setting modes for dosing
    • A61M5/31548—Mechanically operated dose setting member
    • A61M5/3155—Mechanically operated dose setting member by rotational movement of dose setting member, e.g. during setting or filling of a syringe
    • A61M5/31551—Mechanically operated dose setting member by rotational movement of dose setting member, e.g. during setting or filling of a syringe including axial movement of dose setting member
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31566—Means improving security or handling thereof
    • A61M5/31573—Accuracy improving means

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medical Informatics (AREA)
  • Dermatology (AREA)
  • Vascular Medicine (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Materials For Medical Uses (AREA)

Abstract

The present invention provides fluid and material delivery methods and devices for practicing the methods. The invention provides a method of delivering cellular material comprising injecting the cellular material into a subject such that the injected cells retain their inherent morphologic characteristics upon injection. The method comprises the steps of aspirating the cellular material into a fluid delivery device which incorporates a syringe arrangement. The cellular material is aspirated into the main body of the syringe until the desired amount of a material has filled the syringe body. The needle of the fluid delivery device is then inserted into the skin of a subject at an angle about parallel to the skin until a desired depth has been reached. The cellular material is then injected in the subject until the desired volume of material has been injected. The needle of the device is then rotated approximately 45 to 90 degrees and the needle is removed from the injection site.
PCT/US2007/061856 2006-02-09 2007-02-08 Apparatus and methods for delivering fluid and material to a subject WO2007092929A2 (en)

Priority Applications (7)

Application Number Priority Date Filing Date Title
CA2642129A CA2642129C (en) 2006-02-09 2007-02-08 Apparatus and methods for delivering fluid and material to a subject
CA2779561A CA2779561A1 (en) 2006-02-09 2007-02-08 Apparatus and methods for delivering fluid and material to a subject
MX2008010258A MX2008010258A (en) 2006-02-09 2007-02-08 Apparatus and methods for delivering fluid and material to a subject.
EP07763663A EP1986731A4 (en) 2006-02-09 2007-02-08 Apparatus and methods for delivering fluid and material to a subject
JP2008554503A JP4910002B2 (en) 2006-02-09 2007-02-08 Apparatus and methods for delivering fluids and materials to a subject
CN2007800109676A CN101421002B (en) 2006-02-09 2007-02-08 Apparatus and methods for delivering fluid and material to a subject
AU2007213706A AU2007213706B2 (en) 2006-02-09 2007-02-08 Apparatus and methods for delivering fluid and material to a subject

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US77191506P 2006-02-09 2006-02-09
US60/771,915 2006-02-09
US79148906P 2006-04-12 2006-04-12
US60/791,489 2006-04-12
US80324806P 2006-05-26 2006-05-26
US60/803,248 2006-05-26

Publications (2)

Publication Number Publication Date
WO2007092929A2 WO2007092929A2 (en) 2007-08-16
WO2007092929A3 true WO2007092929A3 (en) 2008-11-27

Family

ID=38345956

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2007/061856 WO2007092929A2 (en) 2006-02-09 2007-02-08 Apparatus and methods for delivering fluid and material to a subject

Country Status (10)

Country Link
US (3) US7780635B2 (en)
EP (3) EP2210635A3 (en)
JP (1) JP4910002B2 (en)
CN (2) CN102600548A (en)
AR (1) AR059424A1 (en)
AU (1) AU2007213706B2 (en)
CA (1) CA2642129C (en)
MX (1) MX2008010258A (en)
TW (2) TWI377074B (en)
WO (1) WO2007092929A2 (en)

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US7780635B2 (en) 2010-08-24
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US20100280488A1 (en) 2010-11-04
TWI573603B (en) 2017-03-11

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