WO2007099396A3 - Antibiotic kit and composition and uses thereof - Google Patents

Antibiotic kit and composition and uses thereof Download PDF

Info

Publication number
WO2007099396A3
WO2007099396A3 PCT/IB2006/003975 IB2006003975W WO2007099396A3 WO 2007099396 A3 WO2007099396 A3 WO 2007099396A3 IB 2006003975 W IB2006003975 W IB 2006003975W WO 2007099396 A3 WO2007099396 A3 WO 2007099396A3
Authority
WO
WIPO (PCT)
Prior art keywords
agent
weight
pressurized product
concentration
antibiotic
Prior art date
Application number
PCT/IB2006/003975
Other languages
French (fr)
Other versions
WO2007099396A2 (en
Inventor
Doron Friedman
Alex Besonov
Dov Tamarkin
Meir Eini
Original Assignee
Foamix Ltd
Doron Friedman
Alex Besonov
Dov Tamarkin
Meir Eini
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Foamix Ltd, Doron Friedman, Alex Besonov, Dov Tamarkin, Meir Eini filed Critical Foamix Ltd
Priority to EP06847249A priority Critical patent/EP1919449A2/en
Priority to AU2006339311A priority patent/AU2006339311A1/en
Priority to CA002611577A priority patent/CA2611577A1/en
Publication of WO2007099396A2 publication Critical patent/WO2007099396A2/en
Publication of WO2007099396A3 publication Critical patent/WO2007099396A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/12—Aerosols; Foams
    • A61K9/122—Foams; Dry foams
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles

Abstract

The present invention relates to a therapeutic kit to provide a safe and effective dosage of an antibiotic agent, including an aerosol packaging assembly including: a container accommodating a pressurized product; and an outlet capable of releasing the pressurized product as a foam, wherein the pressurized product comprises a foamable composition including: an antibiotic agent; at least one organic carrier selected from the group consisting of a hydrophobic organic carrier, an organic polar solvent, an emollient and mixtures thereof, at a concentration of about 2 % to about 50 % by weight, a surface- active agent, about 0.01 % to about 5 % by weight of at least one polymeric additive selected from the group consisting of a bioadhesive agent, a gelling agent, a film forming agent and a phase change agent, water; and liquefied or compressed gas propellant at a concentration of about 3 % to about 25 % by weight of the total composition.
PCT/IB2006/003975 2005-06-07 2006-06-07 Antibiotic kit and composition and uses thereof WO2007099396A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
EP06847249A EP1919449A2 (en) 2005-06-07 2006-06-07 Antibiotic kit and composition and uses thereof
AU2006339311A AU2006339311A1 (en) 2005-06-07 2006-06-07 Antibiotic kit and composition and uses thereof
CA002611577A CA2611577A1 (en) 2005-06-07 2006-06-07 Antibiotic kit and composition and uses thereof

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US68824405P 2005-06-07 2005-06-07
US60/688244 2005-06-07

Publications (2)

Publication Number Publication Date
WO2007099396A2 WO2007099396A2 (en) 2007-09-07
WO2007099396A3 true WO2007099396A3 (en) 2008-03-13

Family

ID=38459394

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2006/003975 WO2007099396A2 (en) 2005-06-07 2006-06-07 Antibiotic kit and composition and uses thereof

Country Status (4)

Country Link
EP (1) EP1919449A2 (en)
AU (1) AU2006339311A1 (en)
CA (1) CA2611577A1 (en)
WO (1) WO2007099396A2 (en)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8809314B1 (en) 2012-09-07 2014-08-19 Cubist Pharmacueticals, Inc. Cephalosporin compound
US8945516B2 (en) 2009-10-02 2015-02-03 Foamix Pharmaceuticals Ltd. Surfactant-free water-free foamable compositions, breakable foams and gels and their uses
US9050253B2 (en) 2003-08-04 2015-06-09 Foamix Pharmaceuticals Ltd. Oleaginous pharmaceutical and cosmetic foam
US9161916B2 (en) 2007-12-07 2015-10-20 Foamix Pharmaceuticals Ltd. Carriers, formulations, methods for formulating unstable active agents for external application and uses thereof
US9492412B2 (en) 2002-10-25 2016-11-15 Foamix Pharmaceuticals Ltd. Penetrating pharmaceutical foam

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US8512718B2 (en) 2000-07-03 2013-08-20 Foamix Ltd. Pharmaceutical composition for topical application
IL152486A0 (en) 2002-10-25 2003-05-29 Meir Eini Alcohol-free cosmetic and pharmaceutical foam carrier
US7704518B2 (en) 2003-08-04 2010-04-27 Foamix, Ltd. Foamable vehicle and pharmaceutical compositions thereof
US8900554B2 (en) 2002-10-25 2014-12-02 Foamix Pharmaceuticals Ltd. Foamable composition and uses thereof
US9265725B2 (en) 2002-10-25 2016-02-23 Foamix Pharmaceuticals Ltd. Dicarboxylic acid foamable vehicle and pharmaceutical compositions thereof
US9211259B2 (en) 2002-11-29 2015-12-15 Foamix Pharmaceuticals Ltd. Antibiotic kit and composition and uses thereof
MXPA05004278A (en) 2002-10-25 2005-10-05 Foamix Ltd Cosmetic and pharmaceutical foam.
US20080138296A1 (en) 2002-10-25 2008-06-12 Foamix Ltd. Foam prepared from nanoemulsions and uses
US10117812B2 (en) 2002-10-25 2018-11-06 Foamix Pharmaceuticals Ltd. Foamable composition combining a polar solvent and a hydrophobic carrier
US8119150B2 (en) 2002-10-25 2012-02-21 Foamix Ltd. Non-flammable insecticide composition and uses thereof
US9668972B2 (en) 2002-10-25 2017-06-06 Foamix Pharmaceuticals Ltd. Nonsteroidal immunomodulating kit and composition and uses thereof
US7575739B2 (en) 2003-04-28 2009-08-18 Foamix Ltd. Foamable iodine composition
US8795693B2 (en) 2003-08-04 2014-08-05 Foamix Ltd. Compositions with modulating agents
WO2008075207A2 (en) * 2006-04-04 2008-06-26 Foamix Ltd. Anti-infection augmentation foamable compositions and kit and uses thereof
WO2008038140A2 (en) * 2006-06-07 2008-04-03 Foamix Ltd. Foamable vehicle comprising polypropylene glycol alkyl ether and pharmaceutical compositions thereof
US20080260655A1 (en) 2006-11-14 2008-10-23 Dov Tamarkin Substantially non-aqueous foamable petrolatum based pharmaceutical and cosmetic compositions and their uses
BRPI0811071A2 (en) * 2007-05-04 2014-09-23 Procter & Gamble PRODUCTS, MICROBICIDE COMPOSITIONS, AND METHODS OF USE
US8636982B2 (en) 2007-08-07 2014-01-28 Foamix Ltd. Wax foamable vehicle and pharmaceutical compositions thereof
WO2009069006A2 (en) 2007-11-30 2009-06-04 Foamix Ltd. Foam containing benzoyl peroxide
WO2010041141A2 (en) 2008-10-07 2010-04-15 Foamix Ltd. Oil-based foamable carriers and formulations
EP2242476A2 (en) 2008-01-14 2010-10-27 Foamix Ltd. Poloxamer foamable pharmaceutical compositions with active agents and/or therapeutic cells and uses
WO2009103069A1 (en) 2008-02-15 2009-08-20 Osborne David W Skin penetration enhancing systems for polar drugs
WO2009124386A1 (en) * 2008-04-07 2009-10-15 Interface Biologics Inc. Combination therapy for the treatment of bacterial infections
EP2174650A1 (en) * 2008-10-08 2010-04-14 Polichem SA Modified release emulsions for application to skin or vaginal mucosa
FR2943914A1 (en) * 2009-04-06 2010-10-08 Fabre Pierre Dermo Cosmetique MOISTURE BOTTLE COMPRISING A PHARMACEUTICAL COMPOSITION
US20120087872A1 (en) 2009-04-28 2012-04-12 Foamix Ltd. Foamable Vehicles and Pharmaceutical Compositions Comprising Aprotic Polar Solvents and Uses Thereof
WO2011013009A2 (en) 2009-07-29 2011-02-03 Foamix Ltd. Non surfactant hydro-alcoholic foamable compositions, breakable foams and their uses
WO2011013008A2 (en) 2009-07-29 2011-02-03 Foamix Ltd. Non surface active agent non polymeric agent hydro-alcoholic foamable compositions, breakable foams and their uses
US9849142B2 (en) 2009-10-02 2017-12-26 Foamix Pharmaceuticals Ltd. Methods for accelerated return of skin integrity and for the treatment of impetigo
WO2011061155A1 (en) * 2009-11-17 2011-05-26 Bayer Consumer Care Ag Antifungal formulations and their use
JP6041673B2 (en) 2009-11-23 2016-12-14 キュービスト ファーマシューティカルズ リミテッド ライアビリティ カンパニー Lipopeptide composition and related methods
US8946276B2 (en) 2011-06-28 2015-02-03 Watson Laboratories, Inc. High dosage mucoadhesive metronidazole aqueous-based gel formulations and their use to treat bacterial vaginosis
EP3616695A1 (en) 2011-09-09 2020-03-04 Merck Sharp & Dohme Corp. Methods for treating intrapulmonary infections
CN104023721A (en) 2011-09-21 2014-09-03 干细胞医药有限公司 Beta-lactam compounds for treating diabetes
WO2013042122A1 (en) 2011-09-21 2013-03-28 Cohen Irun R Beta-lactam compounds for enhancing t cell -mediated immune responses
SG190466A1 (en) * 2011-11-18 2013-06-28 Agency Science Tech & Res Methods for diagnosis and/or prognosis of ovarian cancer
CN102526398A (en) * 2012-01-17 2012-07-04 肖文辉 Externally-used traditional Chinese medicinal preparation for treating chronic pelvic inflammation
US8476425B1 (en) 2012-09-27 2013-07-02 Cubist Pharmaceuticals, Inc. Tazobactam arginine compositions
US20140274989A1 (en) 2013-03-15 2014-09-18 Cubist Pharmaceuticals, Inc. Manufacturing beta-lactam combination products
US20140274996A1 (en) 2013-03-15 2014-09-18 Cubist Pharmaceuticals, Inc. Tazobactam and ceftolozane antibiotic compositions
US9872906B2 (en) 2013-03-15 2018-01-23 Merck Sharp & Dohme Corp. Ceftolozane antibiotic compositions
ES2800603T3 (en) 2013-09-09 2021-01-04 Merck Sharp & Dohme Treatment of infections with ceftolozane / tazobactam in patients with renal impairment
US8906898B1 (en) 2013-09-27 2014-12-09 Calixa Therapeutics, Inc. Solid forms of ceftolozane
GB201415776D0 (en) 2014-09-05 2014-10-22 Singh Ishwar And Taylor Edward New antibacterial products
ES2846882T3 (en) 2015-03-23 2021-07-30 Biopharmx Inc Pharmaceutical composition of tetracycline for dermatological use
WO2017009870A1 (en) * 2015-07-13 2017-01-19 Ahir Pramodbhai N A topical formulation for chronic skin and hair disease
CN105726545A (en) * 2016-03-22 2016-07-06 史飞 Cephradine for prevention and/or treatment of TOPK (T-LAK cell-originated protein kinase) activity abnormally increased skin inflammations by inhibition of TOPK
CN106045875A (en) * 2016-06-25 2016-10-26 仇颖超 Preparation method of occrycetin
US10398641B2 (en) 2016-09-08 2019-09-03 Foamix Pharmaceuticals Ltd. Compositions and methods for treating rosacea and acne
PE20200600A1 (en) 2017-02-24 2020-03-10 Univ California COMPOSITIONS AND METHODS TO PROMOTE HAIR GROWTH WITH MPC INHIBITORS
CN110944634A (en) 2017-06-30 2020-03-31 加利福尼亚大学董事会 Compositions and methods for regulating hair growth
AU2018339064A1 (en) * 2017-09-29 2020-02-27 The Regents Of The University Of California Compositions and methods for modulating hair growth
CN111920812B (en) * 2020-07-10 2022-09-20 深圳市臻质医疗科技有限公司 Application of calcium channel inhibitor oxylipine in osteoarthritis
CN114632075B (en) * 2022-05-19 2022-07-15 奥信阳光(北京)药业科技有限公司 Voriconazole aerosol inhalation and application
CN115463091B (en) * 2022-10-27 2023-04-07 新基元(北京)医药科技有限公司 Minocycline foaming agent with improved stability
CN115739051A (en) * 2022-11-30 2023-03-07 浙江工业大学 Hydrophobic membrane and preparation method and application thereof

Citations (5)

* Cited by examiner, † Cited by third party
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WO2004037225A2 (en) * 2002-10-25 2004-05-06 Foamix Ltd. Cosmetic and pharmaceutical foam
WO2004064833A1 (en) * 2003-01-24 2004-08-05 Connetics Australia Pty Ltd. Clindamycin phosphate foam
US20040241099A1 (en) * 2003-05-28 2004-12-02 Popp Karl F. Foamable pharmaceutical compositions and methods for treating a disorder
WO2005011567A2 (en) * 2003-08-04 2005-02-10 Foamix Ltd. Foam carrier containing amphiphilic copolymeric gelling agent
WO2005018530A2 (en) * 2003-08-25 2005-03-03 Foamix Ltd. Penetrating pharmaceutical foam

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004037225A2 (en) * 2002-10-25 2004-05-06 Foamix Ltd. Cosmetic and pharmaceutical foam
WO2004064833A1 (en) * 2003-01-24 2004-08-05 Connetics Australia Pty Ltd. Clindamycin phosphate foam
US20040241099A1 (en) * 2003-05-28 2004-12-02 Popp Karl F. Foamable pharmaceutical compositions and methods for treating a disorder
WO2005011567A2 (en) * 2003-08-04 2005-02-10 Foamix Ltd. Foam carrier containing amphiphilic copolymeric gelling agent
WO2005018530A2 (en) * 2003-08-25 2005-03-03 Foamix Ltd. Penetrating pharmaceutical foam

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9492412B2 (en) 2002-10-25 2016-11-15 Foamix Pharmaceuticals Ltd. Penetrating pharmaceutical foam
US9050253B2 (en) 2003-08-04 2015-06-09 Foamix Pharmaceuticals Ltd. Oleaginous pharmaceutical and cosmetic foam
US9161916B2 (en) 2007-12-07 2015-10-20 Foamix Pharmaceuticals Ltd. Carriers, formulations, methods for formulating unstable active agents for external application and uses thereof
US8945516B2 (en) 2009-10-02 2015-02-03 Foamix Pharmaceuticals Ltd. Surfactant-free water-free foamable compositions, breakable foams and gels and their uses
US8809314B1 (en) 2012-09-07 2014-08-19 Cubist Pharmacueticals, Inc. Cephalosporin compound

Also Published As

Publication number Publication date
AU2006339311A1 (en) 2007-09-07
AU2006339311A2 (en) 2007-09-07
EP1919449A2 (en) 2008-05-14
CA2611577A1 (en) 2007-09-07
WO2007099396A2 (en) 2007-09-07

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