WO2007112305A3 - Methods of preparing hydrogel coatings - Google Patents

Methods of preparing hydrogel coatings Download PDF

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Publication number
WO2007112305A3
WO2007112305A3 PCT/US2007/064782 US2007064782W WO2007112305A3 WO 2007112305 A3 WO2007112305 A3 WO 2007112305A3 US 2007064782 W US2007064782 W US 2007064782W WO 2007112305 A3 WO2007112305 A3 WO 2007112305A3
Authority
WO
WIPO (PCT)
Prior art keywords
hydrogel
methods
coating
medical device
medical devices
Prior art date
Application number
PCT/US2007/064782
Other languages
French (fr)
Other versions
WO2007112305A2 (en
Inventor
Michael E Hawkins
Dirk L Pletcher
Brian Thomas
Kai Zhang
Hallie E Brinkerhuff
Original Assignee
Zimmer Inc
Michael E Hawkins
Dirk L Pletcher
Brian Thomas
Kai Zhang
Hallie E Brinkerhuff
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zimmer Inc, Michael E Hawkins, Dirk L Pletcher, Brian Thomas, Kai Zhang, Hallie E Brinkerhuff filed Critical Zimmer Inc
Priority to AU2007230657A priority Critical patent/AU2007230657B2/en
Priority to EP07759243A priority patent/EP1998823A2/en
Priority to JP2009501749A priority patent/JP2009531083A/en
Priority to CA 2646286 priority patent/CA2646286A1/en
Publication of WO2007112305A2 publication Critical patent/WO2007112305A2/en
Publication of WO2007112305A3 publication Critical patent/WO2007112305A3/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/52Hydrogels or hydrocolloids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28Materials for coating prostheses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2420/00Materials or methods for coatings medical devices
    • A61L2420/02Methods for coating medical devices
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00Materials or treatment for tissue regeneration
    • A61L2430/24Materials or treatment for tissue regeneration for joint reconstruction
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00Stock material or miscellaneous articles
    • Y10T428/31504Composite [nonstructural laminate]
    • Y10T428/31536Including interfacial reaction product of adjacent layers
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00Stock material or miscellaneous articles
    • Y10T428/31504Composite [nonstructural laminate]
    • Y10T428/31678Of metal

Abstract

The present invention provides hydrogel coated, implantable medical devices and 10 methods of coating hydrogels onto implantable medical devices. In one embodiment, a hydrogel coated medical device is formed by 12 physically treating a surface of the medical device, 14 chemically treating the surface, 16 applying a hydrogel precursor and then 18 crosslmking the hydrogel precursor to form a hydrogel coating on the surface of the medical device. The present invention may be particularly applicable for coating articulating surfaces on implantable medical devices such as artificial joints.
PCT/US2007/064782 2006-03-24 2007-03-23 Methods of preparing hydrogel coatings WO2007112305A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
AU2007230657A AU2007230657B2 (en) 2006-03-24 2007-03-23 Methods of preparing hydrogel coatings
EP07759243A EP1998823A2 (en) 2006-03-24 2007-03-23 Methods of preparing hydrogel coatings
JP2009501749A JP2009531083A (en) 2006-03-24 2007-03-23 Method for preparing hydrogel coating
CA 2646286 CA2646286A1 (en) 2006-03-24 2007-03-23 Methods of preparing hydrogel coatings

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US78590606P 2006-03-24 2006-03-24
US60/785,906 2006-03-24
US11/689,754 US8110242B2 (en) 2006-03-24 2007-03-22 Methods of preparing hydrogel coatings
US11/689,754 2007-03-22

Publications (2)

Publication Number Publication Date
WO2007112305A2 WO2007112305A2 (en) 2007-10-04
WO2007112305A3 true WO2007112305A3 (en) 2008-07-17

Family

ID=38477396

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2007/064782 WO2007112305A2 (en) 2006-03-24 2007-03-23 Methods of preparing hydrogel coatings

Country Status (6)

Country Link
US (1) US8110242B2 (en)
EP (1) EP1998823A2 (en)
JP (1) JP2009531083A (en)
AU (1) AU2007230657B2 (en)
CA (1) CA2646286A1 (en)
WO (1) WO2007112305A2 (en)

Families Citing this family (75)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8632583B2 (en) 2011-05-09 2014-01-21 Palmaz Scientific, Inc. Implantable medical device having enhanced endothelial migration features and methods of making the same
US8268340B2 (en) 2002-09-26 2012-09-18 Advanced Bio Prosthetic Surfaces, Ltd. Implantable materials having engineered surfaces and method of making same
EP1551569B1 (en) 2002-09-26 2017-05-10 Advanced Bio Prosthetic Surfaces, Ltd. Implantable materials having engineered surfaces and method of making same
US8679517B2 (en) 2002-09-26 2014-03-25 Palmaz Scientific, Inc. Implantable materials having engineered surfaces made by vacuum deposition and method of making same
WO2005077013A2 (en) 2004-02-06 2005-08-25 Georgia Tech Research Corporation Surface directed cellular attachment
US7910124B2 (en) 2004-02-06 2011-03-22 Georgia Tech Research Corporation Load bearing biocompatible device
US20090088846A1 (en) 2007-04-17 2009-04-02 David Myung Hydrogel arthroplasty device
US8246973B2 (en) 2006-06-21 2012-08-21 Advanced Cardiovascular Systems, Inc. Freeze-thaw method for modifying stent coating
EP2111338A4 (en) * 2007-02-06 2011-08-10 Univ Leland Stanford Junior Hydrogel-metal assembly
US8093039B2 (en) * 2007-04-10 2012-01-10 The Trustees Of The Stevens Institute Of Technology Surfaces differentially adhesive to eukaryotic cells and non-eukaryotic cells
KR20100130178A (en) * 2008-01-09 2010-12-10 이노베이티브 헬스 테크놀로지스, 엘엘씨 Implant pellets and methods for performing bone augmentation and preservation
WO2009108760A2 (en) 2008-02-26 2009-09-03 Board Of Regents, The University Of Texas System Dendritic macroporous hydrogels prepared by crystal templating
WO2009117737A2 (en) * 2008-03-21 2009-09-24 Biomimedica, Inc Methods, devices and compositions for adhering hydrated polymer implants to bone
US20120209396A1 (en) 2008-07-07 2012-08-16 David Myung Orthopedic implants having gradient polymer alloys
AU2009279716A1 (en) 2008-08-05 2010-02-11 Biomimedica, Inc Polyurethane-grafted hydrogels
US8079737B2 (en) * 2009-04-20 2011-12-20 Harvatek Corporation Reflection-type light-emitting module with high heat-dissipating and high light-generating efficiency
EP2609154B1 (en) 2010-08-27 2020-04-22 Hyalex Orthopaedics, Inc. Hydrophobic and hydrophilic interpenetrating polymer networks derived from hydrophobic polymers and methods of preparing the same
US8946194B2 (en) 2010-10-08 2015-02-03 Board Of Regents, University Of Texas System One-step processing of hydrogels for mechanically robust and chemically desired features
JP6042815B2 (en) 2010-10-08 2016-12-14 ザ ボード オブ リージェンツ オブ ザ ユニバーシティ オブ テキサス システム Anti-adhesion barrier membranes using alginate and hyaluronic acid for biomedical applications
US8668743B2 (en) 2010-11-02 2014-03-11 Adam D. Perler Prosthetic device with multi-axis dual bearing assembly and methods for resection
US8728563B2 (en) 2011-05-03 2014-05-20 Palmaz Scientific, Inc. Endoluminal implantable surfaces, stents, and grafts and method of making same
EP2757964B1 (en) 2011-05-26 2016-05-04 Cartiva, Inc. Tapered joint implant and related tools
AU2012319183A1 (en) 2011-10-03 2014-05-22 Biomimedica, Inc. Polymeric adhesive for anchoring compliant materials to another surface
US8556968B2 (en) * 2011-11-09 2013-10-15 Ideal Implant Incorporated Breast implant with low coefficient of friction between internal shells in an aqueous fluid environment
EP2782524B1 (en) 2011-11-21 2017-12-20 Biomimedica, Inc Systems for anchoring orthopaedic implants to bone
BRPI1105297B1 (en) * 2011-12-22 2021-05-11 Universidade Estadual De Campinas - Unicamp process of obtaining polymeric biomaterials via infrared laser
CN104271346B (en) 2012-02-28 2017-10-13 康宁股份有限公司 Glassware with low-friction coating
US10737973B2 (en) 2012-02-28 2020-08-11 Corning Incorporated Pharmaceutical glass coating for achieving particle reduction
US11497681B2 (en) 2012-02-28 2022-11-15 Corning Incorporated Glass articles with low-friction coatings
WO2013148957A1 (en) * 2012-03-28 2013-10-03 Becton, Dickinson And Company Hydrogel adhesion to molded polymers
US10273048B2 (en) 2012-06-07 2019-04-30 Corning Incorporated Delamination resistant glass containers with heat-tolerant coatings
US9034442B2 (en) 2012-11-30 2015-05-19 Corning Incorporated Strengthened borosilicate glass containers with improved damage tolerance
US10117806B2 (en) 2012-11-30 2018-11-06 Corning Incorporated Strengthened glass containers resistant to delamination and damage
US11565027B2 (en) 2012-12-11 2023-01-31 Board Of Regents, The University Of Texas System Hydrogel membrane for adhesion prevention
US9362133B2 (en) * 2012-12-14 2016-06-07 Lam Research Corporation Method for forming a mask by etching conformal film on patterned ashable hardmask
JP6434497B2 (en) * 2013-04-26 2018-12-05 ニューヨーク・ソサイエティ・フォー・ザ・ラプチャード・アンド・クリップルド・メインテイニング・ザ・ホスピタル・フォー・スペシャル・サージェリー Multi-element non-biodegradable implant, method of preparation, and method of implantation
CA2925797A1 (en) * 2013-09-30 2015-04-02 University Of Manitoba Non-adherent hydrogel coating for wound dressings and methods for making the same
GB2521621A (en) * 2013-12-23 2015-07-01 Straumann Holding Ag Process for providing a defined surface topography to at least a portion of a ceramic body
CN105979978A (en) * 2013-12-30 2016-09-28 波士顿科学国际有限公司 Functionalized Lubricious Medical Device Coatings
US10314364B2 (en) 2014-08-27 2019-06-11 Nike, Inc. Soil-shedding article of footwear, and method of using the same
CN107148226B (en) 2014-08-27 2020-05-22 耐克创新有限合伙公司 Article of footwear, article of clothing and article of sports equipment with water-absorbing properties
US10076158B2 (en) 2014-08-27 2018-09-18 Nike, Inc. Article of footwear with soil-shedding performance
US10070686B2 (en) 2014-08-27 2018-09-11 Nike, Inc. Soil-shedding article of footwear, components thereof, and methods of making the article
GB2532837B (en) 2014-08-27 2017-10-25 Nike Innovate Cv Article of footwear with soil-shedding performance
US10899659B2 (en) 2014-09-05 2021-01-26 Corning Incorporated Glass articles and methods for improving the reliability of glass articles
US9997405B2 (en) 2014-09-30 2018-06-12 Lam Research Corporation Feature fill with nucleation inhibition
WO2016085867A1 (en) 2014-11-26 2016-06-02 Corning Incorporated Methods for producing strengthened and durable glass containers
EP3034033A1 (en) 2014-12-16 2016-06-22 Nobel Biocare Services AG Dental implant
WO2016148648A1 (en) 2015-03-19 2016-09-22 Nanyang Technological University A stent assembly and method of preparing the stent assembly
EP3892241A1 (en) 2015-03-31 2021-10-13 Cartiva, Inc. Drill bit for carpometacarpal implant
CA2981061A1 (en) 2015-03-31 2016-10-06 Cartiva, Inc. Hydrogel implants with porous materials and methods
CA2981074C (en) 2015-04-14 2023-03-28 Cartiva, Inc. Tooling for creating tapered opening in tissue and related methods
EP3878484A1 (en) 2015-04-16 2021-09-15 Hollister Incorporated Hydrophilic coatings and methods of forming the same
US20160314964A1 (en) 2015-04-21 2016-10-27 Lam Research Corporation Gap fill using carbon-based films
US11077228B2 (en) 2015-08-10 2021-08-03 Hyalex Orthopaedics, Inc. Interpenetrating polymer networks
EP3150564B1 (en) 2015-09-30 2018-12-05 Corning Incorporated Halogenated polyimide siloxane chemical compositions and glass articles with halogenated polylmide siloxane low-friction coatings
WO2017075435A1 (en) 2015-10-30 2017-05-04 Corning Incorporated Glass articles with mixed polymer and metal oxide coatings
AU2016380252B2 (en) * 2015-12-30 2021-03-11 Cytec Industries Inc. Surface-treated polymeric particles, slurry containing the same and use thereof
GB2546319B (en) 2016-01-15 2019-07-03 Cook Medical Technologies Llc Coated medical device and method of coating such a device
US10531705B2 (en) 2016-03-02 2020-01-14 Nike, Inc. Hydrogel tie layer
US10362834B2 (en) 2016-03-02 2019-07-30 Nike, Inc. Hydrogel connection
US10455893B2 (en) 2016-03-02 2019-10-29 Nike, Inc. Hydrogel with mesh for soil deflection
US10675609B2 (en) 2016-03-02 2020-06-09 Nike, Inc. Articles with soil-shedding performance
TWI700175B (en) 2017-08-01 2020-08-01 荷蘭商耐基創新公司 Method of manufacturing a component of an outsole for use in an article of footwear
KR101960952B1 (en) * 2017-08-11 2019-03-26 원광대학교산학협력단 Biodegradable/biocompatible kagome cage with enhanced a mechanical property for spinal fusion
CN107595445B (en) * 2017-09-13 2023-07-11 北京安颂科技有限公司 Low-abrasion knee joint femoral condyle prosthesis
KR102608646B1 (en) 2017-10-19 2023-12-01 나이키 이노베이트 씨.브이. Outsole and outsole manufacturing method
JP7155579B2 (en) * 2018-03-30 2022-10-19 株式会社リコー Hydrogel structure, manufacturing method thereof, and organ model
CN108498875A (en) * 2018-04-24 2018-09-07 苏州脉悦医疗科技有限公司 A kind of Bioabsorbable medical instrument and preparation method thereof
US10869950B2 (en) 2018-07-17 2020-12-22 Hyalex Orthopaedics, Inc. Ionic polymer compositions
RU2684178C1 (en) * 2018-07-25 2019-04-04 Анна Владимировна Алабут Method of rehabilitation after total knee endoprosthesis replacementin patients with sarcopenia
US11912894B2 (en) 2018-11-26 2024-02-27 Cornell University Antimicrobial and antifouling conformal hydrogel coatings
WO2020120805A2 (en) 2018-12-14 2020-06-18 Institut Químic De Sarrià Cets Fundació Privada Heterogeneous scaffolds and methods of functionalising surfaces
CN112480452B (en) * 2020-11-27 2021-08-24 中国科学院兰州化学物理研究所 Method for modifying polymer surface by anisotropic texture/metal ion implantation
US11801143B2 (en) 2021-07-01 2023-10-31 Hyalex Orthopaedics, Inc. Multi-layered biomimetic osteochondral implants and methods of using thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6372283B1 (en) * 1999-04-02 2002-04-16 Medtronic, Inc. Plasma process for surface modification of pyrolitic carbon
FR2865939A1 (en) * 2004-02-06 2005-08-12 Biomatlante Forming calcium phosphate-based coating or fixing active agent(s) on surface of biocompatible substrate, e.g. implant or prosthesis, using matrix of silanated organic polymer in hydrogel form

Family Cites Families (196)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB919390A (en) 1960-12-14 1963-02-27 Kurashiki Rayon Kk Polyvinyl alcohol fibres having excellent dyeability and whiteness
US3875302A (en) 1970-09-16 1975-04-01 Kuraray Co Gelled vinyl alcohol polymers and articles therefrom
US3862265A (en) 1971-04-09 1975-01-21 Exxon Research Engineering Co Polymers with improved properties and process therefor
DE2364675C2 (en) 1972-12-29 1983-06-23 Kuraray Co., Ltd., Kurashiki, Okayama Copolymer consisting of a polymer main chain and polymer side chains and its use for the manufacture of articles for biomedical purposes
US4058491A (en) 1975-02-11 1977-11-15 Plastomedical Sciences, Inc. Cationic hydrogels based on heterocyclic N-vinyl monomers
US4071508A (en) 1975-02-11 1978-01-31 Plastomedical Sciences, Inc. Anionic hydrogels based on hydroxyalkyl acrylates and methacrylates
US4036788A (en) 1975-02-11 1977-07-19 Plastomedical Sciences, Inc. Anionic hydrogels based on heterocyclic N-vinyl monomers
US4060678A (en) 1975-02-11 1977-11-29 Plastomedical Sciences, Inc. Cationic hydrogels based on hydroxyalkyl acrylates and methacrylates
SU1243627A3 (en) 1979-12-05 1986-07-07 Дзе Кендалл Компани (Фирма) Jelly-forming composition
US4379874A (en) 1980-07-07 1983-04-12 Stoy Vladimir A Polymer composition comprising polyacrylonitrile polymer and multi-block copolymer
CA1181915A (en) 1981-02-05 1985-02-05 Nippon Oil Co., Ltd. Process for preparing a hydrogel
US4451599A (en) 1981-04-01 1984-05-29 American Can Company Plasticized EVOH and process and products utilizing same
US4734097A (en) 1981-09-25 1988-03-29 Nippon Oil Company, Ltd. Medical material of polyvinyl alcohol and process of making
US4699146A (en) 1982-02-25 1987-10-13 Valleylab, Inc. Hydrophilic, elastomeric, pressure-sensitive adhesive
JPS5930881A (en) 1982-08-13 1984-02-18 Nippon Oil Co Ltd Manufacture of low-temperature insulating gel
JPS5956446A (en) 1982-09-24 1984-03-31 Nippon Oil Co Ltd Method for lowering flexibility of frozen polyvinyl alcohol gel
GB8311788D0 (en) 1983-04-29 1983-06-02 Coopervision Uk Hydrogel contact lenses
US4464438A (en) 1983-05-02 1984-08-07 Mobil Oil Corporation Blends of polyvinyl alcohol and ethylene-vinyl alcohol copolymer as grease resistant melt extrudable films
US4859719A (en) 1983-09-08 1989-08-22 Minnesota Mining And Manufacturing Company Polymer blends with high water absorption
US4771089A (en) 1983-09-08 1988-09-13 Minnesota Mining And Manufacturing Co. Polymer blends with high water absorption
DE3410241A1 (en) 1984-03-21 1985-10-03 Hoechst Ag, 6230 Frankfurt THERMOPLASTICALLY PROCESSABLE POLYVINYL ALCOHOL COMPOSITIONS, METHOD FOR THEIR PRODUCTION AND FILMS AND MOLDED PARTS MADE THEREOF
JPH0678460B2 (en) 1985-05-01 1994-10-05 株式会社バイオマテリアル・ユニバース Porous transparent polyvinyl alcohol gel
US4640941A (en) 1985-11-25 1987-02-03 Alcon Laboratories Hydrogels containing siloxane comonomers
JPS6323126A (en) 1986-02-13 1988-01-30 Bio Material Yunibaasu:Kk Soft contact lens and its production
GB8611838D0 (en) 1986-05-15 1986-06-25 Yarsley Technical Centre Ltd Hydrophilic copolymers
JPS6317904A (en) 1986-07-09 1988-01-25 Mitsubishi Chem Ind Ltd Production of crosslinked porous polyvinyl alcohol particle
JPH0611290B2 (en) 1986-11-05 1994-02-16 住友ベークライト株式会社 Γ-ray sterilization method for polyvinyl alcohol gel
PL151581B1 (en) 1986-12-30 1990-09-28 Method of manufacturing of hydrogel dressing
US5244799A (en) 1987-05-20 1993-09-14 Anderson David M Preparation of a polymeric hydrogel containing micropores and macropores for use as a cell culture substrate
US5306311A (en) 1987-07-20 1994-04-26 Regen Corporation Prosthetic articular cartilage
US4772287A (en) 1987-08-20 1988-09-20 Cedar Surgical, Inc. Prosthetic disc and method of implanting
JP2746387B2 (en) 1988-09-22 1998-05-06 株式会社ビーエムジー Method for producing polyvinyl alcohol hydrogel
JPH0286838A (en) 1988-09-22 1990-03-27 Terumo Corp Water insoluble hydrogel and production thereof
DE3835840A1 (en) 1988-10-21 1990-05-31 Hoechst Ag GRAY POLYMERISATES CONTAINING POLYVINYL ACETAL GROUPS ON POLYURETHANE GRAIN BASES, METHOD FOR THEIR PRODUCTION AND THEIR USE
US4851168A (en) 1988-12-28 1989-07-25 Dow Corning Corporation Novel polyvinyl alcohol compositions and products prepared therefrom
US4915974A (en) 1989-02-17 1990-04-10 Nabisco Brands, Inc. Polyvinyl oleate as a fat replacement
IT1233599B (en) 1989-05-30 1992-04-06 Butterfly Srl POLYMERIC COMPOSITIONS FOR THE PRODUCTION OF BIODEGRADABLE PLASTIC ITEMS AND PROCEDURES FOR THEIR PREPARATION
US5364547A (en) 1989-06-09 1994-11-15 The Dow Chemical Company Lubricants containing perfluorocyclobutane rings
JP3116958B2 (en) 1989-06-30 2000-12-11 ポケット・コンピュータ・コーポレーション Memory card holding structure
US5288765A (en) 1989-08-03 1994-02-22 Spherilene S.R.L. Expanded articles of biodegradable plastics materials and a method for their production
US5118779A (en) 1989-10-10 1992-06-02 Polymedica Industries, Inc. Hydrophilic polyurethane elastomers
US5157093A (en) 1990-05-10 1992-10-20 Ciba-Geigy Corporation Hydroxyethyl cellulose derivatives containing pendant (meth)acryloyl units bound through urethane groups and hydrogel contact lenses made therefrom
US5028648A (en) 1990-07-12 1991-07-02 Air Products And Chemicals, Inc. Extrudable polyvinyl alcohol compositions containing thermoplastic polyurethane
US5122565A (en) 1990-10-26 1992-06-16 Shell Oil Company Stabilized polyketone polymers containing a mixture of a hydroxyapatite and an alumina hydrogel
US5410016A (en) 1990-10-15 1995-04-25 Board Of Regents, The University Of Texas System Photopolymerizable biodegradable hydrogels as tissue contacting materials and controlled-release carriers
TW203065B (en) 1990-10-24 1993-04-01 Hoechst Ag
US5189097A (en) 1990-12-07 1993-02-23 Rohm And Haas Company Polymeric blends
US5362803A (en) 1990-12-07 1994-11-08 Rohm And Haas Company Polymeric blends of polyvinyl alcohol copolymers with copolymers of unsaturated monomers
US5192326A (en) 1990-12-21 1993-03-09 Pfizer Hospital Products Group, Inc. Hydrogel bead intervertebral disc nucleus
US5047055A (en) 1990-12-21 1991-09-10 Pfizer Hospital Products Group, Inc. Hydrogel intervertebral disc nucleus
JP3007903B2 (en) 1991-03-29 2000-02-14 京セラ株式会社 Artificial disc
US5276079A (en) 1991-11-15 1994-01-04 Minnesota Mining And Manufacturing Company Pressure-sensitive poly(n-vinyl lactam) adhesive composition and method for producing and using same
US5552096A (en) 1991-12-13 1996-09-03 Exxon Chemical Patents Inc. Multiple reaction process in melt processing equipment
US5681300A (en) 1991-12-17 1997-10-28 The Procter & Gamble Company Absorbent article having blended absorbent core
US5260066A (en) 1992-01-16 1993-11-09 Srchem Incorporated Cryogel bandage containing therapeutic agent
CA2096386A1 (en) 1992-05-18 1993-11-19 Masahiro Kamauchi Lithium secondary battery
US6162456A (en) 1992-09-24 2000-12-19 Ortho-Mcneil Pharmaceutical, Inc. Adhesive transdermal drug delivery matrix of a physical blend of hydrophilic and hydrophobic polymers
US5407055A (en) 1992-11-19 1995-04-18 Kao Corporation Conveyor apparatus and method having flexible goods receptacle members
US5336551A (en) 1992-12-14 1994-08-09 Mizu Systems, Inc. Reinforced polyvinyl alcohol hydrogels containing uniformly dispersed crystalline fibrils and method for preparing same
US5358525A (en) 1992-12-28 1994-10-25 Fox John E Bearing surface for prosthesis and replacement of meniscal cartilage
US5256751A (en) 1993-02-08 1993-10-26 Vistakon, Inc. Ophthalmic lens polymer incorporating acyclic monomer
US5709854A (en) 1993-04-30 1998-01-20 Massachusetts Institute Of Technology Tissue formation by injecting a cell-polymeric solution that gels in vivo
FR2704431B1 (en) 1993-04-30 1995-07-21 Sebbin Laboratoires Use of hydrogels based on hyaluronic acid and / or polydeoxyribonucleotides as filling materials for prostheses and prostheses resulting therefrom.
CA2149900C (en) 1993-09-24 2003-06-24 Yasuo Shikinami Implant material
US5540033A (en) 1994-01-10 1996-07-30 Cambrex Hydrogels Integrated Manufacturing process for hydrogels
US5527271A (en) 1994-03-30 1996-06-18 Bristol-Myers Squibb Co. Thermoplastic hydrogel impregnated composite material
US5723331A (en) 1994-05-05 1998-03-03 Genzyme Corporation Methods and compositions for the repair of articular cartilage defects in mammals
AU2621295A (en) 1994-05-24 1995-12-18 Smith & Nephew Plc Intervertebral disc implant
US5834029A (en) 1994-07-20 1998-11-10 Cytotherapeutics, Inc. Nerve guidance channel containing bioartificial three-dimensional hydrogel extracellular matrix derivatized with cell adhesive peptide fragment
EP0700671B1 (en) 1994-09-08 2001-08-08 Stryker Technologies Corporation Hydrogel intervertebral disc nucleus
US6180606B1 (en) 1994-09-28 2001-01-30 Gensci Orthobiologics, Inc. Compositions with enhanced osteogenic potential, methods for making the same and uses thereof
EP0785774B1 (en) 1994-10-12 2001-01-31 Focal, Inc. Targeted delivery via biodegradable polymers
DE69532856T2 (en) 1994-10-17 2005-04-21 Raymedica Inc Spinal disc-GRAFT
US5716404A (en) 1994-12-16 1998-02-10 Massachusetts Institute Of Technology Breast tissue engineering
US5632774A (en) 1995-01-17 1997-05-27 Babian; Hamik In-the-shell hydration to make implant filler material and prosthesis employing same
US5919570A (en) 1995-02-01 1999-07-06 Schneider Inc. Slippery, tenaciously adhering hydrogel coatings containing a polyurethane-urea polymer hydrogel commingled with a poly(N-vinylpyrrolidone) polymer hydrogel, coated polymer and metal substrate materials, and coated medical devices
US6017577A (en) 1995-02-01 2000-01-25 Schneider (Usa) Inc. Slippery, tenaciously adhering hydrophilic polyurethane hydrogel coatings, coated polymer substrate materials, and coated medical devices
US5576072A (en) * 1995-02-01 1996-11-19 Schneider (Usa), Inc. Process for producing slippery, tenaciously adhering hydrogel coatings containing a polyurethane-urea polymer hydrogel commingled with at least one other, dissimilar polymer hydrogel
US5941909A (en) 1995-02-14 1999-08-24 Mentor Corporation Filling material for soft tissue implant prostheses and implants made therewith
US6962979B1 (en) 1995-03-14 2005-11-08 Cohesion Technologies, Inc. Crosslinkable biomaterial compositions containing hydrophobic and hydrophilic crosslinking agents
US5900245A (en) 1996-03-22 1999-05-04 Focal, Inc. Compliant tissue sealants
ATE369402T1 (en) 1995-03-23 2007-08-15 Genzyme Corp REDOX AND PHOTOINITIATOR SYSTEM FOR PRIMERING IMPROVED ADHESION OF GELS TO SUBSTRATES
JPH08283570A (en) 1995-04-17 1996-10-29 Sumitomo Chem Co Ltd Resin composition
US6129761A (en) 1995-06-07 2000-10-10 Reprogenesis, Inc. Injectable hydrogel compositions
US6509098B1 (en) 1995-11-17 2003-01-21 Massachusetts Institute Of Technology Poly(ethylene oxide) coated surfaces
PT876165E (en) 1995-12-18 2006-10-31 Angiotech Biomaterials Corp COMPOSITIONS OF RETICULATED POLYMERS AND PROCESSES FOR THEIR USE
EP0784987B1 (en) 1996-01-16 2003-10-01 Mentor Corporation Method of making in situ filler material for mammary, penile and testicular prosthesis and tissue expanders
US6015576A (en) 1997-08-29 2000-01-18 Bio-Sphere Technology, Inc. Method for inducing a systemic immune response to an antigen
US6207185B1 (en) 1996-03-22 2001-03-27 Bio-Sphere Technology Method for inducing a systemic immune response to an HIV antigen
US6117449A (en) 1996-03-22 2000-09-12 Bio-Sphere Technology, Inc. Method for inducing a systemic immune response to a hepatitis antigen
US6069295A (en) * 1996-05-10 2000-05-30 Isotis B.V. Implant material
PT910412E (en) 1996-07-01 2003-09-30 Univ Utrecht HYDROLOGICAL HYDROGEES FOR CONTROLLED LIBERATION
US6706690B2 (en) 1999-06-10 2004-03-16 Baxter Healthcare Corporation Hemoactive compositions and methods for their manufacture and use
US6063061A (en) 1996-08-27 2000-05-16 Fusion Medical Technologies, Inc. Fragmented polymeric compositions and methods for their use
US6184197B1 (en) 1996-09-19 2001-02-06 The Procter & Gamble Company Polymeric compound comprising one or more active alcohols
EP0934041B1 (en) 1996-10-24 2011-06-15 Covidien AG Hydrogel wound dressing and the method of making and using the same
EP1230902A1 (en) 1996-11-15 2002-08-14 Advanced Bio Surfaces, Inc. Biomaterial system for in situ tissue repair
US6139963A (en) 1996-11-28 2000-10-31 Kuraray Co., Ltd. Polyvinyl alcohol hydrogel and process for producing the same
US6224893B1 (en) 1997-04-11 2001-05-01 Massachusetts Institute Of Technology Semi-interpenetrating or interpenetrating polymer networks for drug delivery and tissue engineering
US20030008396A1 (en) 1999-03-17 2003-01-09 Ku David N. Poly(vinyl alcohol) hydrogel
US5981826A (en) 1997-05-05 1999-11-09 Georgia Tech Research Corporation Poly(vinyl alcohol) cryogel
US6271278B1 (en) 1997-05-13 2001-08-07 Purdue Research Foundation Hydrogel composites and superporous hydrogel composites having fast swelling, high mechanical strength, and superabsorbent properties
US6060701A (en) 1997-05-27 2000-05-09 Turbochef Technologies, Inc. Compact quick-cooking convectional oven
GB9714580D0 (en) 1997-07-10 1997-09-17 Wardlaw Douglas Prosthetic intervertebral disc nucleus
AU1664099A (en) 1997-09-18 1999-04-05 Tyco Group S.A.R.L. Hydrogel wound dressing and the method of making and using the same
US6375634B1 (en) 1997-11-19 2002-04-23 Oncology Innovations, Inc. Apparatus and method to encapsulate, kill and remove malignancies, including selectively increasing absorption of x-rays and increasing free-radical damage to residual tumors targeted by ionizing and non-ionizing radiation therapy
US5891826A (en) 1997-11-26 1999-04-06 Eastman Kodak Company Affixing thermal dye transfer image on magnet
US6428811B1 (en) 1998-03-11 2002-08-06 Wm. Marsh Rice University Temperature-sensitive polymer/nanoshell composites for photothermally modulated drug delivery
US6007833A (en) 1998-03-19 1999-12-28 Surmodics, Inc. Crosslinkable macromers bearing initiator groups
US6040493A (en) 1998-04-24 2000-03-21 Replication Medical, Inc. Bioreactor wound dressing
US6132468A (en) 1998-09-10 2000-10-17 Mansmann; Kevin A. Arthroscopic replacement of cartilage using flexible inflatable envelopes
US6861067B2 (en) 1998-09-17 2005-03-01 Sherwood Services Ag Hydrogel wound dressing and the method of making and using the same
US6630457B1 (en) 1998-09-18 2003-10-07 Orthogene Llc Functionalized derivatives of hyaluronic acid, formation of hydrogels in situ using same, and methods for making and using same
US6211296B1 (en) 1998-11-05 2001-04-03 The B. F. Goodrich Company Hydrogels containing substances
FR2786400B1 (en) 1998-11-30 2002-05-10 Imedex Biomateriaux PROCESS FOR THE PREPARATION OF A COLLAGENIC MATERIAL HAVING IN VIVO CONTROLLED BIODEGRADATION SPEED AND MATERIALS OBTAINED
US6451346B1 (en) 1998-12-23 2002-09-17 Amgen Inc Biodegradable pH/thermosensitive hydrogels for sustained delivery of biologically active agents
CA2371833C (en) 1999-02-19 2009-09-15 Denki Kagaku Kogyo Kabushiki Kaisha Hyaluronic acid gel composition, process for its production and medical material containing it
DE60038010T2 (en) 1999-04-12 2009-03-05 Cornell Research Foundation, Inc. HYDROGEL-FORMING SYSTEM WITH HYDROPHOBIC AND HYDROPHILIC COMPONENTS
US6268405B1 (en) 1999-05-04 2001-07-31 Porex Surgical, Inc. Hydrogels and methods of making and using same
US7491235B2 (en) * 1999-05-10 2009-02-17 Fell Barry M Surgically implantable knee prosthesis
KR100698559B1 (en) 1999-06-11 2007-03-21 넥타르 테라퓨틱스 에이엘, 코포레이션 Hydrogels derived from chitosan and polyethylene glycol or related polymers
US6333029B1 (en) 1999-06-30 2001-12-25 Ethicon, Inc. Porous tissue scaffoldings for the repair of regeneration of tissue
US6306424B1 (en) 1999-06-30 2001-10-23 Ethicon, Inc. Foam composite for the repair or regeneration of tissue
JP4247519B2 (en) 1999-08-18 2009-04-02 イントリンジック セラピューティックス インコーポレイテッド Apparatus and method for nucleus augmentation and retention
US6287870B1 (en) 1999-08-20 2001-09-11 Robert A. Levine Method and assembly for separating formed constituents from a liquid constituent in a complex biologic fluid sample
US6783546B2 (en) 1999-09-13 2004-08-31 Keraplast Technologies, Ltd. Implantable prosthetic or tissue expanding device
US6371984B1 (en) 1999-09-13 2002-04-16 Keraplast Technologies, Ltd. Implantable prosthetic or tissue expanding device
US6232406B1 (en) 1999-09-30 2001-05-15 Replication Medical Inc. Hydrogel and method of making
US6387325B1 (en) 1999-10-08 2002-05-14 Becton Dickinson & Company Assembly for separating formed constituents from a liquid constituent in a complex biologic fluid sample
US6710126B1 (en) 1999-11-15 2004-03-23 Bio Cure, Inc. Degradable poly(vinyl alcohol) hydrogels
WO2001055212A2 (en) 2000-01-27 2001-08-02 The General Hospital Corporation Delivery of therapeutic biological from implantable tissue matrices
US6632246B1 (en) 2000-03-14 2003-10-14 Chondrosite, Llc Cartilage repair plug
US6626945B2 (en) 2000-03-14 2003-09-30 Chondrosite, Llc Cartilage repair plug
US6629997B2 (en) 2000-03-27 2003-10-07 Kevin A. Mansmann Meniscus-type implant with hydrogel surface reinforced by three-dimensional mesh
US6969480B2 (en) 2000-05-12 2005-11-29 Matregen Corp. Method of producing structures using centrifugal forces
US6710104B2 (en) 2000-05-29 2004-03-23 Kawamura Institute Of Chemical Research Organic/inorganic hybrid hydrogel and manufacturing method therefor
US6533817B1 (en) 2000-06-05 2003-03-18 Raymedica, Inc. Packaged, partially hydrated prosthetic disc nucleus
US7186419B2 (en) 2000-08-25 2007-03-06 Contura Sa Polyacrylamide hydrogel for arthritis
US20020026244A1 (en) 2000-08-30 2002-02-28 Trieu Hai H. Intervertebral disc nucleus implants and methods
US6620196B1 (en) 2000-08-30 2003-09-16 Sdgi Holdings, Inc. Intervertebral disc nucleus implants and methods
WO2002034111A2 (en) 2000-10-24 2002-05-02 Cryolife, Inc. In situ bioprosthetic filler and methods, particularly for the in situ formation of vertebral disc bioprosthetics
US6783793B1 (en) * 2000-10-26 2004-08-31 Advanced Cardiovascular Systems, Inc. Selective coating of medical devices
US9050192B2 (en) 2001-02-05 2015-06-09 Formae, Inc. Cartilage repair implant with soft bearing surface and flexible anchoring device
JP4116447B2 (en) 2001-05-01 2008-07-09 エイ.ブイ.トップチーブ インスティテュート オブ ペトロケミカル シンセシス Hydrogel composition
ES2587187T3 (en) 2001-05-01 2016-10-21 A. V. Topchiev Institute Of Petrochemical Synthesis Biphasic water absorbent bioadhesive composition
US8840918B2 (en) 2001-05-01 2014-09-23 A. V. Topchiev Institute of Petrochemical Synthesis, Russian Academy of Sciences Hydrogel compositions for tooth whitening
US6608117B1 (en) 2001-05-11 2003-08-19 Nanosystems Research Inc. Methods for the preparation of cellular hydrogels
CA2449433A1 (en) * 2001-06-20 2003-01-03 Microvention, Inc. Medical devices having full or partial polymer coatings and their methods of manufacture
US6780840B1 (en) 2001-10-09 2004-08-24 Tissue Adhesive Technologies, Inc. Method for making a light energized tissue adhesive
US6855743B1 (en) 2001-10-29 2005-02-15 Nanosystems Research, Inc. Reinforced, laminated, impregnated, and composite-like materials as crosslinked polyvinyl alcohol hydrogel structures
US6783721B2 (en) 2001-10-30 2004-08-31 Howmedica Osteonics Corp. Method of making an ion treated hydrogel
WO2003059200A1 (en) 2002-01-04 2003-07-24 Massachusetts General Hospital A high modulus crosslinked polyethylene with reduced residual free radical concentration prepared below the melt
US6949590B2 (en) 2002-01-10 2005-09-27 University Of Washington Hydrogels formed by non-covalent linkages
US20040131582A1 (en) 2002-02-26 2004-07-08 Grinstaff Mark W. Novel dendritic polymers and their biomedical uses
WO2003089506A1 (en) 2002-04-22 2003-10-30 Purdue Research Foundation Hydrogels having enhanced elasticity and mechanical strength properties
US7015262B2 (en) * 2002-05-01 2006-03-21 Lifescan, Inc. Hydrophilic coatings for medical implements
US7122602B2 (en) 2002-06-21 2006-10-17 Isp Investments Inc. Process of making polymeric hydrogels by reactive extrusion
US7033393B2 (en) 2002-06-27 2006-04-25 Raymedica, Inc. Self-transitioning spinal disc anulus occulsion device and method of use
US7485670B2 (en) 2002-08-02 2009-02-03 Cambridge Polymer Group, Inc. Systems and methods for controlling and forming polymer gels
US7745532B2 (en) 2002-08-02 2010-06-29 Cambridge Polymer Group, Inc. Systems and methods for controlling and forming polymer gels
EP1549689B1 (en) 2002-10-02 2010-05-26 Coloplast A/S A hydrogel
US20050069572A1 (en) 2002-10-09 2005-03-31 Jennifer Elisseeff Multi-layered polymerizing hydrogels for tissue regeneration
DE60336158D1 (en) 2002-10-11 2011-04-07 Univ Connecticut ON SEMICRISTALLINE THERMOPLASTIC POLYURETHANES BASED FOR NANOSTRUCTURED HARD SEGMENTS BASED FORM MEMORY PILARMERS
US6844067B2 (en) 2002-10-24 2005-01-18 Toda Kogyo Corporation Black iron-based particles and black toner containing the same
US8110222B2 (en) 2002-11-15 2012-02-07 Ut-Battelle, Llc. Composite material
US6733533B1 (en) 2002-11-19 2004-05-11 Zimmer Technology, Inc. Artificial spinal disc
WO2004047691A1 (en) 2002-11-21 2004-06-10 Sdgi Holdings, Inc. Systems and techniques for interbody spinal stablization with expandable devices
WO2004050715A2 (en) 2002-11-27 2004-06-17 Isp Investments Inc. Tough polymers
JP4890764B2 (en) 2002-12-18 2012-03-07 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア Biocompatible hydrogel bone-like complex
US7004971B2 (en) 2002-12-31 2006-02-28 Depuy Acromed, Inc. Annular nucleus pulposus replacement
US6982298B2 (en) 2003-01-10 2006-01-03 The Cleveland Clinic Foundation Hydroxyphenyl cross-linked macromolecular network and applications thereof
ATE416730T1 (en) 2003-01-16 2008-12-15 Replication Medical Inc HYDROGEL-BASED PROSTHESIS FOR AT LEAST PARTIAL REPLACEMENT OF THE NUCLEUS OF A DISC
US20070003525A1 (en) 2003-01-31 2007-01-04 Moehlenbruck Jeffrey W Hydrogel compositions comprising nucleus pulposus tissue
US6994730B2 (en) 2003-01-31 2006-02-07 Howmedica Osteonics Corp. Meniscal and tibial implants
EP1595899B1 (en) 2003-02-17 2009-11-25 Kawamura Institute Of Chemical Research Polymer gel containing biocompatible material, dry gel, and process for producing polymer gel
US20040242770A1 (en) 2003-04-16 2004-12-02 Feldstein Mikhail M. Covalent and non-covalent crosslinking of hydrophilic polymers and adhesive compositions prepared therewith
EP1626799B1 (en) 2003-04-30 2010-04-14 Drexel University Thermogelling polymer blends for biomaterial applications
US7067169B2 (en) * 2003-06-04 2006-06-27 Chemat Technology Inc. Coated implants and methods of coating
WO2004109053A2 (en) 2003-06-04 2004-12-16 Sun Drilling Products Corporation Lost circulation material blend offering high fluid loss with minimum solids
NL1023924C2 (en) 2003-07-15 2005-01-18 Stichting Tech Wetenschapp Tissue replacement material.
US7736619B2 (en) 2003-11-05 2010-06-15 Ust Inc. Hydrogel compositions and manufacturing process for ultrasound couplants
KR100553327B1 (en) 2003-11-18 2006-02-20 광주과학기술원 Siloxane monomers containing trifluorovinylether group, sol-gel hybrid polymers prepared by using the siloxane monomers
FR2866571B1 (en) 2004-02-20 2007-09-21 Philippe Zanchetta USE OF A MIXTURE OF SPECIFIC POLYSACCHARIDES AS INDICATED BY THE EZBONE INVENTOR COMPRISING HYALURONIC ACID, CHONDROID SULFATE, DERMATANE SULFATE AND HEPARIN IN BONE HEALING.
CN100412097C (en) 2004-03-05 2008-08-20 日本合成化学工业株式会社 Aqueous emulsion and uses thereof
EP1593400A1 (en) 2004-05-04 2005-11-09 Depuy Products, Inc. Hybrid biologic-synthetic bioabsorbable scaffolds
CN100575368C (en) 2004-08-04 2009-12-30 积水化学工业株式会社 The manufacture method of the manufacture method of polyvinyl acetal resin, polyvinyl butyral resin and esterified polyvinyl alcohol resin
EP1796747B1 (en) 2004-08-27 2017-07-05 Antonio Lauto Bioadhesve film for tissue repair
US7235592B2 (en) 2004-10-12 2007-06-26 Zimmer Gmbh PVA hydrogel
WO2006075392A1 (en) 2005-01-14 2006-07-20 Mitsui Chemicals, Inc. Polyvinyl acetal resin varnish, gelling agent, nonaqueous electrolyte and electrochemical element
CA2591921A1 (en) 2005-02-23 2006-08-31 Zimmer Technology, Inc. Blend hydrogels and methods of making
US7291169B2 (en) 2005-04-15 2007-11-06 Zimmer Technology, Inc. Cartilage implant
US20070004861A1 (en) 2005-07-01 2007-01-04 Kevin Cai High melt strength polypropylene resins and method for making same
ITTO20050549A1 (en) 2005-08-03 2007-02-04 Consiglio Nazionale Ricerche COMPOSITE MATERIAL INJECTABLE TO BE USED AS A BONUS SUBSTITUTE
US7601383B2 (en) 2006-02-28 2009-10-13 Advanced Cardiovascular Systems, Inc. Coating construct containing poly (vinyl alcohol)
WO2009038922A1 (en) 2007-08-21 2009-03-26 Boston Scientific Limited Forming embolic particles
JP5297742B2 (en) 2008-09-26 2013-09-25 株式会社青木科学研究所 Powder-containing oil-based lubricant for molds, electrostatic coating method using the same, and electrostatic coating apparatus

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6372283B1 (en) * 1999-04-02 2002-04-16 Medtronic, Inc. Plasma process for surface modification of pyrolitic carbon
FR2865939A1 (en) * 2004-02-06 2005-08-12 Biomatlante Forming calcium phosphate-based coating or fixing active agent(s) on surface of biocompatible substrate, e.g. implant or prosthesis, using matrix of silanated organic polymer in hydrogel form

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