WO2007122581A3 - Compositions and kits of phenylephrine - Google Patents

Compositions and kits of phenylephrine Download PDF

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Publication number
WO2007122581A3
WO2007122581A3 PCT/IB2007/051470 IB2007051470W WO2007122581A3 WO 2007122581 A3 WO2007122581 A3 WO 2007122581A3 IB 2007051470 W IB2007051470 W IB 2007051470W WO 2007122581 A3 WO2007122581 A3 WO 2007122581A3
Authority
WO
WIPO (PCT)
Prior art keywords
phenylephrine
kits
compositions
composition
mixtures
Prior art date
Application number
PCT/IB2007/051470
Other languages
French (fr)
Other versions
WO2007122581A2 (en
Inventor
Kelly Lee Martin
Jayant Eknath Khanolkar
Douglas William Gledhill
Susan Elaine Criss
Niranjan Ramji
Elaine Rose Costeines
Thomas Edward Huetter
Radhika R Iyer
Daren K Anness
Original Assignee
Procter & Gamble
Kelly Lee Martin
Jayant Eknath Khanolkar
Douglas William Gledhill
Susan Elaine Criss
Niranjan Ramji
Elaine Rose Costeines
Thomas Edward Huetter
Radhika R Iyer
Daren K Anness
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=48805455&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=WO2007122581(A3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from US11/408,299 external-priority patent/US10022339B2/en
Priority to EP07735602.0A priority Critical patent/EP2046289B1/en
Priority to ES07735602.0T priority patent/ES2454967T3/en
Priority to JP2009506029A priority patent/JP5362549B2/en
Priority to AU2007242419A priority patent/AU2007242419B2/en
Application filed by Procter & Gamble, Kelly Lee Martin, Jayant Eknath Khanolkar, Douglas William Gledhill, Susan Elaine Criss, Niranjan Ramji, Elaine Rose Costeines, Thomas Edward Huetter, Radhika R Iyer, Daren K Anness filed Critical Procter & Gamble
Priority to MX2008013257A priority patent/MX2008013257A/en
Priority to PL07735602T priority patent/PL2046289T3/en
Priority to CA2650036A priority patent/CA2650036C/en
Priority to BRPI0710483A priority patent/BRPI0710483B8/en
Publication of WO2007122581A2 publication Critical patent/WO2007122581A2/en
Publication of WO2007122581A3 publication Critical patent/WO2007122581A3/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/05—Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/473—Quinolines; Isoquinolines ortho- or peri-condensed with carbocyclic ring systems, e.g. acridines, phenanthridines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A61K31/522—Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/60—Salicylic acid; Derivatives thereof
    • A61K31/612—Salicylic acid; Derivatives thereof having the hydroxy group in position 2 esterified, e.g. salicylsulfuric acid
    • A61K31/616—Salicylic acid; Derivatives thereof having the hydroxy group in position 2 esterified, e.g. salicylsulfuric acid by carboxylic acids, e.g. acetylsalicylic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/04—Drugs for disorders of the respiratory system for throat disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/14—Antitussive agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents

Abstract

The invention relates to a clear device: comprising a composition contained in a device; wherein said composition comprising a pharmaceutical active selected from the group consisting of phenylephrine, its free and addition salt forms, and mixtures thereof. Also disclosed are kits comprising: a composition contained in a device; wherein said composition comprising a pharmaceutical active selected from the group consisting of phenylephrine, its free and addition salt forms, and mixtures thereof.
PCT/IB2007/051470 2006-04-21 2007-04-20 Compositions and kits of phenylephrine WO2007122581A2 (en)

Priority Applications (8)

Application Number Priority Date Filing Date Title
BRPI0710483A BRPI0710483B8 (en) 2006-04-21 2007-04-20 device comprising compositions with phenylephrine, phenylephrine hydrochloride, phenylephrine hydrobromide, and mixtures thereof and kits useful for the treatment of respiratory diseases
CA2650036A CA2650036C (en) 2006-04-21 2007-04-20 Compositions and kits useful for treatment of respiratory illness
ES07735602.0T ES2454967T3 (en) 2006-04-21 2007-04-20 Phenylephrine compositions and kits
JP2009506029A JP5362549B2 (en) 2006-04-21 2007-04-20 Compositions and kits useful for the treatment of respiratory diseases
AU2007242419A AU2007242419B2 (en) 2006-04-21 2007-04-20 Compositions and kits useful for treatment of respiratory illness
EP07735602.0A EP2046289B1 (en) 2006-04-21 2007-04-20 Compositions and kits of phenylephrine
MX2008013257A MX2008013257A (en) 2006-04-21 2007-04-20 Compositions and kits useful for treatment of respiratory illness.
PL07735602T PL2046289T3 (en) 2006-04-21 2007-04-20 Compositions and kits of phenylephrine

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US11/408,299 US10022339B2 (en) 2006-04-21 2006-04-21 Compositions and methods useful for treatment of respiratory illness
US11/408,299 2006-04-21
US11/657,860 US20070249727A1 (en) 2006-04-21 2007-01-25 Compositions and kits useful for treatment of respiratory illness
US11/657,860 2007-01-25

Publications (2)

Publication Number Publication Date
WO2007122581A2 WO2007122581A2 (en) 2007-11-01
WO2007122581A3 true WO2007122581A3 (en) 2009-07-02

Family

ID=48805455

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2007/051470 WO2007122581A2 (en) 2006-04-21 2007-04-20 Compositions and kits of phenylephrine

Country Status (11)

Country Link
US (6) US20070249727A1 (en)
EP (1) EP2046289B1 (en)
JP (1) JP5362549B2 (en)
CN (1) CN101631539A (en)
AU (1) AU2007242419B2 (en)
BR (1) BRPI0710483B8 (en)
CA (1) CA2650036C (en)
ES (1) ES2454967T3 (en)
MX (1) MX2008013257A (en)
PL (1) PL2046289T3 (en)
WO (1) WO2007122581A2 (en)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8992980B2 (en) 2002-10-25 2015-03-31 Boehringer Ingelheim Vetmedica Gmbh Water-soluble meloxicam granules
EP1568369A1 (en) 2004-02-23 2005-08-31 Boehringer Ingelheim Vetmedica Gmbh Use of meloxicam for the treatment of respiratory diseases in pigs
US20070249727A1 (en) 2006-04-21 2007-10-25 The Proctor & Gamble Company Compositions and kits useful for treatment of respiratory illness
US10022339B2 (en) 2006-04-21 2018-07-17 The Procter & Gamble Company Compositions and methods useful for treatment of respiratory illness
US20070254027A1 (en) * 2006-04-28 2007-11-01 The Procter & Gamble Company Compositions and methods useful for treatment of respiratory illness
CN106109397A (en) * 2009-06-04 2016-11-16 爱尔开-阿贝优公司 Comprise the stabilized composition of at least one adrenergic compounds
US9101529B2 (en) * 2009-10-12 2015-08-11 Boehringer Ingelheim Vetmedica Gmbh Containers for compositions comprising meloxicam
KR20130037237A (en) 2010-03-03 2013-04-15 베링거잉겔하임베트메디카게엠베하 Use of meloxicam for the long-term treatment of musculoskeletal disorders in cats
US9795568B2 (en) 2010-05-05 2017-10-24 Boehringer Ingelheim Vetmedica Gmbh Low concentration meloxicam tablets
US9457085B2 (en) 2013-02-13 2016-10-04 The Procter & Gamble Company Anise flavored medication
WO2016024928A1 (en) * 2014-08-14 2016-02-18 Bi̇ofarma İlaç Sanayi̇ Ve Ti̇caret A.Ş. Taste masked paracetamol formulations
US11213480B1 (en) 2015-08-06 2022-01-04 Hikma Pharmaceuticals International Limited Phenylephrine hydrochloride ready-to-use solution
CN110809465B (en) * 2017-03-27 2022-10-25 帕拉卡普制药有限公司 Preparation containing expectorant or decongestant
GR1009541B (en) * 2018-02-26 2019-06-07 Λαμδα Φαρμακευτικα Εργαστηρια Εφαρμοσμενης Ερευνας & Αναπτυξης Α.Ε. Oral pharmaceutical solutions comprising melatonin
EP3793535A1 (en) 2018-05-16 2021-03-24 Bayer Healthcare LLC High concentration suspension formulation for cold and flu soft gel capsule medications
US20230201140A1 (en) * 2021-12-29 2023-06-29 Baxter International, Inc. Phenylephrine premix formulations and uses thereof

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0473159A1 (en) * 1990-08-30 1992-03-04 Senju Pharmaceutical Co., Ltd. Stable aqueous preparation
JPH0780760B2 (en) * 1986-07-28 1995-08-30 ライオン株式会社 Stabilized phenylephrine liquid agent
US6218428B1 (en) * 2000-04-28 2001-04-17 Emil Chynn Ophthalmic composition
WO2005023236A1 (en) * 2003-08-22 2005-03-17 Pediamed Pharmaceuticals, Inc. Phenylephrine tannate, pyrilamine tannate, and dextromethorphan tannate salts in pharmaceutical compositions

Family Cites Families (72)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB836747A (en) 1957-07-31 1960-06-09 Upjohn Co Improvements in or relating to steroidal compounds and compositions and the preparation thereof
GB895495A (en) 1960-01-20 1962-05-02 Boots Pure Drug Co Ltd Amino-acetamidoximes and their preparation
US3169092A (en) 1963-09-26 1965-02-09 Richardson Merrell Inc Stabilization of amines by tartrazine and bisulfite
US3293045A (en) 1963-10-18 1966-12-20 Pfizer & Co C Increasing the flavor strength of anethole, cinnamaldehyde and methyl salicylate with maltol
GB1121358A (en) 1965-10-21 1968-07-24 Bristol Myers Co Aerosol manufacture
US3480185A (en) 1966-06-20 1969-11-25 Johnson & Johnson Charged effervescing agent and medicament dispensing metering valve-actuated aerosol container producing a dose of medicament and carbonation in water
US3710795A (en) * 1970-09-29 1973-01-16 Alza Corp Drug-delivery device with stretched, rate-controlling membrane
US4049803A (en) 1976-04-26 1977-09-20 Bristol-Myers Company Augmentation of blood levels of aspirin
ATE72944T1 (en) 1987-09-04 1992-03-15 Procter & Gamble FILLING COMPOSITIONS CONTAINING PSYLLIUM.
DK0387933T3 (en) 1989-03-16 1993-12-06 Procter & Gamble Psyllium-containing, baked cookie compositions
US5178025A (en) 1990-08-31 1993-01-12 Innovative Medical Engineering, Inc. Tiltable lift seat devices
US5196436A (en) 1990-10-31 1993-03-23 The Procter & Gamble Company Dextromethorphan antitussive compositions
US5296209A (en) 1992-01-17 1994-03-22 Colgate Palmolive Company Pet chew product having oral care properties
CA2146637C (en) * 1992-10-09 2001-02-13 James Grigg Upson Pharmaceutical compositions and methods for treating cold symptoms
US5480674A (en) 1993-06-25 1996-01-02 Firmenich Incorporated Flavor composition for an oral electrolyte rehydration solution
JP3643604B2 (en) 1993-09-17 2005-04-27 セイコーインスツル株式会社 Grinding method in internal grinding machine
JP3021312B2 (en) * 1994-03-15 2000-03-15 千寿製薬株式会社 Method for stabilizing pranoprofen and stable aqueous solution of pranoprofen
GB9422571D0 (en) 1994-11-09 1995-01-04 Whitehall Lab Ltd Haemorrihoidal compositions and method of use
JPH09286726A (en) 1996-04-18 1997-11-04 Takeda Chem Ind Ltd Oral solution
JPH09286724A (en) 1996-04-19 1997-11-04 Takeda Chem Ind Ltd Liquid stablizer for oral administration
JPH09286723A (en) 1996-04-19 1997-11-04 Takeda Chem Ind Ltd Improved oral solution
US5660833A (en) 1996-06-05 1997-08-26 Medenica; Rajko D. Anti-tussive composition
FR2751875B1 (en) 1996-08-05 1998-12-24 Scr Newpharm NOVEL STABLE LIQUID FORMULATIONS BASED ON PARACETAMOL AND THEIR METHOD OF PREPARATION
JPH10167988A (en) 1996-10-09 1998-06-23 Takeda Chem Ind Ltd Oral liquid preparation
US5759579A (en) * 1996-12-05 1998-06-02 American Home Products Corporation Pharmaceutical suspension systems
ATE241341T1 (en) * 1997-09-10 2003-06-15 Takeda Chemical Industries Ltd STABILIZED PHARMACEUTICAL COMPOSITION
ES2180274T3 (en) 1998-01-30 2003-02-01 Novartis Consumer Health Sa NASAL DISSOLUTIONS.
JP3262091B2 (en) * 1998-12-25 2002-03-04 ライオン株式会社 Eyewash composition, method for eliminating stickiness of eyewash composition, and eyewash set
US20020082307A1 (en) 1999-01-11 2002-06-27 Dobrozsi Douglas Joseph Compositions having improved stability
US6287597B1 (en) * 1999-03-12 2001-09-11 Carter-Wallace, Inc. Antihistaminic/decongestant compositions
CN1270707C (en) 2000-05-17 2006-08-23 千寿制药株式会社 Ophthalmic solution
FR2809619B1 (en) 2000-06-06 2004-09-24 Pharmatop NOVEL AQUEOUS FORMULATIONS OF OXIDATION-SENSITIVE ACTIVE INGREDIENTS AND PROCESS FOR OBTAINING THEM
US6572849B2 (en) * 2000-09-20 2003-06-03 Lee Shahinian, Jr. Self-preserved antibacterial nasal, inhalable, and topical ophthalmic preparations and medications
JP2002212107A (en) 2001-01-22 2002-07-31 Taisho Pharmaceut Co Ltd Topical application composition
US20030026826A1 (en) 2001-07-31 2003-02-06 Cherukuri Subraman Rao Sugar-free chewy products and protein-based chewy products and methods for making the same
WO2003011306A1 (en) 2001-07-31 2003-02-13 Wyeth Sucralose formulations to mask unpleasant tastes
JP2003063962A (en) * 2001-08-29 2003-03-05 Taisho Pharmaceut Co Ltd Composition for rhinostenosis
US20030083354A1 (en) 2001-10-26 2003-05-01 Pediamed Pharmaceuticals, Inc. Phenylephrine tannate and pyrilamine tannate salts in pharmaceutical compositions
EP1461031B1 (en) * 2001-11-29 2016-06-29 Emisphere Technologies, Inc. Formulations for oral administration of cromolyn sodium
US7101572B2 (en) * 2001-12-07 2006-09-05 Unilab Pharmatech, Ltd. Taste masked aqueous liquid pharmaceutical composition
US20030170371A1 (en) 2002-01-10 2003-09-11 Cargill, Inc. High fat/fiber composition
AU2003208967A1 (en) * 2002-02-04 2003-09-02 Pharmacia Corporation A combination for treating cold and cough
CA2502825A1 (en) 2002-10-22 2004-05-06 Dainippon Pharmaceutical Co., Ltd. Stabilized composition
US20050214349A1 (en) 2002-10-30 2005-09-29 Li Nie Extruded gluten based pet chew bodies
US20060193959A1 (en) 2002-10-30 2006-08-31 Li Nie Low calorie injection molded starch-based pet chew bodies
US20040259955A1 (en) * 2002-11-08 2004-12-23 Boehringer Ingelheim International Gmbh New pharmaceutical compositions containing ambroxol and isopropamide iodide
DE10261061A1 (en) 2002-12-24 2004-07-15 Nutrinova Nutrition Specialties & Food Ingredients Gmbh Dietary food to positively influence cardiovascular health
JP2004217596A (en) 2003-01-17 2004-08-05 Taisho Pharmaceut Co Ltd Eye drop agent composition
US20040162273A1 (en) * 2003-01-23 2004-08-19 The Procter & Gamble Company Powder pharmaceutical compositions
JP2004300138A (en) 2003-03-18 2004-10-28 Takeda Chem Ind Ltd Stabilized oral solid preparation
WO2004084637A1 (en) 2003-03-24 2004-10-07 Council Of Scientific And Industrial Research A high fibre biscuit composition and a process for preparing the same
JP4473539B2 (en) 2003-08-12 2010-06-02 エスエス製薬株式会社 Pharmaceutical composition
US7118772B2 (en) 2003-09-18 2006-10-10 General Mills, Inc. Inulin infused fruit and method of preparation
DE10358213A1 (en) 2003-12-12 2005-07-28 Clariant Gmbh Polyethylene glycol and its preparation
US20050266032A1 (en) 2003-12-17 2005-12-01 Sovereign Pharmaceuticals, Ltd. Dosage form containing multiple drugs
JP2005247802A (en) * 2004-03-08 2005-09-15 Zeria Pharmaceut Co Ltd Eye drops
US20050266031A1 (en) 2004-05-25 2005-12-01 Jay Dickerson Pharmaceutical suspension composition
WO2006022996A2 (en) 2004-08-04 2006-03-02 Sovereign Pharmaceuticals, Ltd. Dosage form containing multiple drugs
US20060039973A1 (en) 2004-08-19 2006-02-23 Mary Aldritt Effervescent composition including water soluble dietary fiber
US20060148837A1 (en) * 2005-01-04 2006-07-06 Everett Laboratories, Inc. Compositions and methods for treatment of coughing, sneezing, rhinorrhea, and/or nasal obstruction
US20060188450A1 (en) * 2005-02-24 2006-08-24 Tim Clarot System and method for suppressing a cough
DE102006030757A1 (en) 2005-07-18 2007-02-01 Carl Zeiss Smt Ag Illumination system for microlithography-projection illumination installation, has mirror arrangement that includes mirrors, and is so arranged that common-polarization degree change by arrangement is smaller than degree change by mirrors
US20070098785A1 (en) * 2005-11-02 2007-05-03 Tim Clarot Medicant delivery system and device
CA2636061C (en) 2006-01-27 2015-06-02 Cadbury Adams Usa Llc Flavor-enhancing compositions, methods of manufacture, and methods of use
US8940796B2 (en) * 2006-02-21 2015-01-27 Wyeth Llc Phenylephrine liquid formulations
US10022339B2 (en) 2006-04-21 2018-07-17 The Procter & Gamble Company Compositions and methods useful for treatment of respiratory illness
US20070249727A1 (en) 2006-04-21 2007-10-25 The Proctor & Gamble Company Compositions and kits useful for treatment of respiratory illness
US20070254027A1 (en) 2006-04-28 2007-11-01 The Procter & Gamble Company Compositions and methods useful for treatment of respiratory illness
US20080014275A1 (en) 2006-07-13 2008-01-17 Buehler Gail K Pharmaceutical suspensions and related methods
US20080014274A1 (en) 2006-07-14 2008-01-17 Wyeth Enhanced stability phenylephrine liquid compositions
US20080069874A1 (en) * 2006-09-15 2008-03-20 Auriga Laboratories, Inc. Kits for Prevention and Treatment of Rhinitis
AP2015008704A0 (en) 2013-02-04 2015-09-30 Aft Pharmaceuticals Ltd A combination medicament comprising phenylephrine and paracetamol

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0780760B2 (en) * 1986-07-28 1995-08-30 ライオン株式会社 Stabilized phenylephrine liquid agent
EP0473159A1 (en) * 1990-08-30 1992-03-04 Senju Pharmaceutical Co., Ltd. Stable aqueous preparation
US6218428B1 (en) * 2000-04-28 2001-04-17 Emil Chynn Ophthalmic composition
WO2005023236A1 (en) * 2003-08-22 2005-03-17 Pediamed Pharmaceuticals, Inc. Phenylephrine tannate, pyrilamine tannate, and dextromethorphan tannate salts in pharmaceutical compositions

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
ANONYMOUS: "New technologies unveiled by Magplastic at dringTEC-PETpoint 2005", MAGPLASTIC, BLAW-MOULDING TECHNOLOGY, 12 September 2005 (2005-09-12), Voury, Switzerland, XP002520888, Retrieved from the Internet <URL:http://www.magplastic.com/PressReviews/2005%20PR%20-%20New%20technologies.pdf> [retrieved on 20090525] *
DATABASE WPI Week 199539, Derwent World Patents Index; AN 1988-080731, XP002520889 *

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