WO2007124270A3 - Method and apparatus for detection of nervous system disorders - Google Patents

Method and apparatus for detection of nervous system disorders Download PDF

Info

Publication number
WO2007124270A3
WO2007124270A3 PCT/US2007/066334 US2007066334W WO2007124270A3 WO 2007124270 A3 WO2007124270 A3 WO 2007124270A3 US 2007066334 W US2007066334 W US 2007066334W WO 2007124270 A3 WO2007124270 A3 WO 2007124270A3
Authority
WO
WIPO (PCT)
Prior art keywords
nervous system
system disorders
therapy
detection
certain embodiments
Prior art date
Application number
PCT/US2007/066334
Other languages
French (fr)
Other versions
WO2007124270A2 (en
Inventor
Touby A Drew
Eric J Panken
Jonathan C Werder
David L Carlson
Original Assignee
Medtronic Inc
Touby A Drew
Eric J Panken
Jonathan C Werder
David L Carlson
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medtronic Inc, Touby A Drew, Eric J Panken, Jonathan C Werder, David L Carlson filed Critical Medtronic Inc
Priority to EP07760403A priority Critical patent/EP2012662A2/en
Publication of WO2007124270A2 publication Critical patent/WO2007124270A2/en
Publication of WO2007124270A3 publication Critical patent/WO2007124270A3/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/02Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
    • A61B5/024Detecting, measuring or recording pulse rate or heart rate
    • A61B5/02405Determining heart rate variability
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/24Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/316Modalities, i.e. specific diagnostic methods
    • A61B5/318Heart-related electrical modalities, e.g. electrocardiography [ECG]
    • A61B5/346Analysis of electrocardiograms
    • A61B5/349Detecting specific parameters of the electrocardiograph cycle
    • A61B5/352Detecting R peaks, e.g. for synchronising diagnostic apparatus; Estimating R-R interval
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/24Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/316Modalities, i.e. specific diagnostic methods
    • A61B5/369Electroencephalography [EEG]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/24Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/316Modalities, i.e. specific diagnostic methods
    • A61B5/369Electroencephalography [EEG]
    • A61B5/372Analysis of electroencephalograms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/24Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/316Modalities, i.e. specific diagnostic methods
    • A61B5/369Electroencephalography [EEG]
    • A61B5/375Electroencephalography [EEG] using biofeedback
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/24Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/316Modalities, i.e. specific diagnostic methods
    • A61B5/369Electroencephalography [EEG]
    • A61B5/386Accessories or supplementary instruments therefor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/40Detecting, measuring or recording for evaluating the nervous system
    • A61B5/4076Diagnosing or monitoring particular conditions of the nervous system
    • A61B5/4094Diagnosing or monitoring seizure diseases, e.g. epilepsy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/72Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7271Specific aspects of physiological measurement analysis
    • A61B5/7275Determining trends in physiological measurement data; Predicting development of a medical condition based on physiological measurements, e.g. determining a risk factor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/3606Implantable neurostimulators for stimulating central or peripheral nerve system adapted for a particular treatment
    • A61N1/36082Cognitive or psychiatric applications, e.g. dementia or Alzheimer's disease
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N2/00Magnetotherapy
    • A61N2/004Magnetotherapy specially adapted for a specific therapy
    • A61N2/006Magnetotherapy specially adapted for a specific therapy for magnetic stimulation of nerve tissue
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16HHEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H20/00ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance
    • G16H20/30ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to physical therapies or activities, e.g. physiotherapy, acupressure or exercising
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16HHEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H40/00ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices
    • G16H40/60ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices
    • G16H40/67ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for remote operation
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16HHEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/20ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/72Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7221Determining signal validity, reliability or quality
    • GPHYSICS
    • G06COMPUTING; CALCULATING OR COUNTING
    • G06FELECTRIC DIGITAL DATA PROCESSING
    • G06F2218/00Aspects of pattern recognition specially adapted for signal processing
    • G06F2218/12Classification; Matching
    • G06F2218/14Classification; Matching by matching peak patterns

Abstract

Systems and methods for detecting and/or treating nervous system disorders, such as seizures, are disclosed. Certain embodiments of the invention relate generally to implantable medical devices (IMDs) adapted to detect and treat nervous system disorders in patients with an IMD. Certain embodiments of the invention include detection of seizures based upon comparisons of long-term and short-term representations of physiological signals. Further embodiments of the invention include preparing for the delivery of therapy by warming up therapy delviery components prior to the expected delivery of therapy.
PCT/US2007/066334 2006-04-21 2007-04-10 Method and apparatus for detection of nervous system disorders WO2007124270A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP07760403A EP2012662A2 (en) 2006-04-21 2007-04-10 Method and apparatus for detection of nervous system disorders

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US79401706P 2006-04-21 2006-04-21
US60/794,017 2006-04-21
US11/609,465 US8165683B2 (en) 2006-04-21 2006-12-12 Method and apparatus for detection of nervous system disorders
US11/609,465 2006-12-12
US11/677,360 2007-02-21
US11/677,360 US7979130B2 (en) 2006-04-21 2007-02-21 Method and apparatus for detection of nervous system disorders

Publications (2)

Publication Number Publication Date
WO2007124270A2 WO2007124270A2 (en) 2007-11-01
WO2007124270A3 true WO2007124270A3 (en) 2008-05-08

Family

ID=38620468

Family Applications (2)

Application Number Title Priority Date Filing Date
PCT/US2007/061141 WO2007124190A2 (en) 2006-04-21 2007-01-26 Method and apparatus for detection of nervous system disorders
PCT/US2007/066334 WO2007124270A2 (en) 2006-04-21 2007-04-10 Method and apparatus for detection of nervous system disorders

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PCT/US2007/061141 WO2007124190A2 (en) 2006-04-21 2007-01-26 Method and apparatus for detection of nervous system disorders

Country Status (3)

Country Link
US (3) US8165683B2 (en)
EP (2) EP2010051A2 (en)
WO (2) WO2007124190A2 (en)

Families Citing this family (70)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9050469B1 (en) 2003-11-26 2015-06-09 Flint Hills Scientific, Llc Method and system for logging quantitative seizure information and assessing efficacy of therapy using cardiac signals
US9314633B2 (en) 2008-01-25 2016-04-19 Cyberonics, Inc. Contingent cardio-protection for epilepsy patients
US8260426B2 (en) 2008-01-25 2012-09-04 Cyberonics, Inc. Method, apparatus and system for bipolar charge utilization during stimulation by an implantable medical device
US8565867B2 (en) 2005-01-28 2013-10-22 Cyberonics, Inc. Changeable electrode polarity stimulation by an implantable medical device
WO2007075477A2 (en) * 2005-12-19 2007-07-05 University Of Florida Closed-loop state-dependent seizure prevention systems
US7996079B2 (en) 2006-01-24 2011-08-09 Cyberonics, Inc. Input response override for an implantable medical device
US7974697B2 (en) 2006-01-26 2011-07-05 Cyberonics, Inc. Medical imaging feedback for an implantable medical device
EP2026874B1 (en) 2006-03-29 2015-05-20 Dignity Health Vagus nerve stimulation system
US20070249956A1 (en) * 2006-04-21 2007-10-25 Medtronic, Inc. Method and apparatus for detection of nervous system disorders
US7761146B2 (en) * 2006-04-21 2010-07-20 Medtronic, Inc. Method and apparatus for detection of nervous system disorders
US8165683B2 (en) 2006-04-21 2012-04-24 Medtronic, Inc. Method and apparatus for detection of nervous system disorders
US7962220B2 (en) 2006-04-28 2011-06-14 Cyberonics, Inc. Compensation reduction in tissue stimulation therapy
US7869885B2 (en) 2006-04-28 2011-01-11 Cyberonics, Inc Threshold optimization for tissue stimulation therapy
US7869867B2 (en) 2006-10-27 2011-01-11 Cyberonics, Inc. Implantable neurostimulator with refractory stimulation
US7974701B2 (en) 2007-04-27 2011-07-05 Cyberonics, Inc. Dosing limitation for an implantable medical device
AU2008283852A1 (en) * 2007-08-06 2009-02-12 Great Lakes Biosciences, Llc Apparatus and method for remote assessment and therapy management in medical devices via interface systems
EP2211708A1 (en) * 2007-10-23 2010-08-04 Optima Neuroscience, Inc. System for seizure monitoring and detection
US8382667B2 (en) 2010-10-01 2013-02-26 Flint Hills Scientific, Llc Detecting, quantifying, and/or classifying seizures using multimodal data
US8571643B2 (en) 2010-09-16 2013-10-29 Flint Hills Scientific, Llc Detecting or validating a detection of a state change from a template of heart rate derivative shape or heart beat wave complex
US8337404B2 (en) 2010-10-01 2012-12-25 Flint Hills Scientific, Llc Detecting, quantifying, and/or classifying seizures using multimodal data
US8204603B2 (en) 2008-04-25 2012-06-19 Cyberonics, Inc. Blocking exogenous action potentials by an implantable medical device
JP2011528933A (en) * 2008-07-22 2011-12-01 カーディアック ペースメイカーズ, インコーポレイテッド Morphological feature evaluation in implantable medical devices
EP2313148B1 (en) 2008-07-30 2013-08-21 Ecole Polytechnique Fédérale de Lausanne Apparatus for optimized stimulation of a neurological target
US8457747B2 (en) 2008-10-20 2013-06-04 Cyberonics, Inc. Neurostimulation with signal duration determined by a cardiac cycle
US8417344B2 (en) 2008-10-24 2013-04-09 Cyberonics, Inc. Dynamic cranial nerve stimulation based on brain state determination from cardiac data
CA2743575C (en) 2008-11-12 2017-01-31 Ecole Polytechnique Federale De Lausanne Microfabricated neurostimulation device
EP2375974A2 (en) * 2009-01-13 2011-10-19 Purdue Research Foundation, Inc. Low-power real-time seizure detection system
US20100191304A1 (en) 2009-01-23 2010-07-29 Scott Timothy L Implantable Medical Device for Providing Chronic Condition Therapy and Acute Condition Therapy Using Vagus Nerve Stimulation
US8827912B2 (en) 2009-04-24 2014-09-09 Cyberonics, Inc. Methods and systems for detecting epileptic events using NNXX, optionally with nonlinear analysis parameters
US8239028B2 (en) 2009-04-24 2012-08-07 Cyberonics, Inc. Use of cardiac parameters in methods and systems for treating a chronic medical condition
CA2771204C (en) 2009-04-30 2017-09-19 Chemaphor Inc. Methods and compositions for improving the health of animals
US20110015537A1 (en) * 2009-07-15 2011-01-20 General Electric Company Method, apparatus and computer program for monitoring specific cerebral activity
DE102009043728A1 (en) * 2009-10-01 2011-04-07 Albert Hesse Method of treating obesity
CA2782710C (en) 2009-12-01 2019-01-22 Ecole Polytechnique Federale De Lausanne Microfabricated neurostimulation device and methods of making and using the same
EP2552536B1 (en) 2010-04-01 2016-06-08 Ecole Polytechnique Fédérale de Lausanne (EPFL) Device for interacting with neurological tissue
US8831732B2 (en) 2010-04-29 2014-09-09 Cyberonics, Inc. Method, apparatus and system for validating and quantifying cardiac beat data quality
US8562536B2 (en) 2010-04-29 2013-10-22 Flint Hills Scientific, Llc Algorithm for detecting a seizure from cardiac data
US8649871B2 (en) 2010-04-29 2014-02-11 Cyberonics, Inc. Validity test adaptive constraint modification for cardiac data used for detection of state changes
US8456295B2 (en) 2010-05-26 2013-06-04 General Electric Company Alarm generation method for patient monitoring, physiological monitoring apparatus and computer program product for a physiological monitoring apparatus
US8679009B2 (en) 2010-06-15 2014-03-25 Flint Hills Scientific, Llc Systems approach to comorbidity assessment
US8641646B2 (en) 2010-07-30 2014-02-04 Cyberonics, Inc. Seizure detection using coordinate data
EP2621333B1 (en) 2010-09-28 2015-07-29 Masimo Corporation Depth of consciousness monitor including oximeter
US8684921B2 (en) 2010-10-01 2014-04-01 Flint Hills Scientific Llc Detecting, assessing and managing epilepsy using a multi-variate, metric-based classification analysis
US8665096B2 (en) 2010-12-21 2014-03-04 General Electric Company Alarm control method, physiological monitoring apparatus, and computer program product for a physiological monitoring apparatus
US9504390B2 (en) 2011-03-04 2016-11-29 Globalfoundries Inc. Detecting, assessing and managing a risk of death in epilepsy
US9498162B2 (en) 2011-04-25 2016-11-22 Cyberonics, Inc. Identifying seizures using heart data from two or more windows
US9402550B2 (en) 2011-04-29 2016-08-02 Cybertronics, Inc. Dynamic heart rate threshold for neurological event detection
US9888861B2 (en) 2011-08-25 2018-02-13 Medtronic, Inc. Method and apparatus for detecting a biomarker in the presence of electrical stimulation
US10448839B2 (en) 2012-04-23 2019-10-22 Livanova Usa, Inc. Methods, systems and apparatuses for detecting increased risk of sudden death
US8977909B2 (en) * 2012-07-19 2015-03-10 Dell Products L.P. Large log file diagnostics system
US8985057B2 (en) 2012-08-24 2015-03-24 Donald J. Woodward System for development of therapeutic drugs and procedures
US9849025B2 (en) 2012-09-07 2017-12-26 Yale University Brain cooling system
US10220211B2 (en) 2013-01-22 2019-03-05 Livanova Usa, Inc. Methods and systems to diagnose depression
US10706732B1 (en) * 2013-02-28 2020-07-07 Nervanix, LLC Attention variability feedback based on changes in instructional attribute values
US11311718B2 (en) 2014-05-16 2022-04-26 Aleva Neurotherapeutics Sa Device for interacting with neurological tissue and methods of making and using the same
CN106455985B (en) 2014-05-16 2019-09-17 阿莱瓦神经治疗股份有限公司 With the device and production and preparation method thereof of nerve fiber interaction
US9403011B2 (en) 2014-08-27 2016-08-02 Aleva Neurotherapeutics Leadless neurostimulator
US9474894B2 (en) 2014-08-27 2016-10-25 Aleva Neurotherapeutics Deep brain stimulation lead
WO2016057553A1 (en) 2014-10-07 2016-04-14 Masimo Corporation Modular physiological sensors
ES2903443T3 (en) 2015-04-28 2022-04-01 Avivagen Inc Oxidized carotenoids and components thereof to prevent necrotic enteritis
US20160331973A1 (en) * 2015-05-15 2016-11-17 The Charles Stark Draper Laboratory, Inc. Implantable hub and satellite system for neural recording and stimulation
EP3313270B1 (en) 2015-06-24 2023-07-26 Cardiac Pacemakers, Inc. Event detection using a variable threshold
WO2017134587A1 (en) 2016-02-02 2017-08-10 Aleva Neurotherapeutics, Sa Treatment of autoimmune diseases with deep brain stimulation
JP2019510534A (en) * 2016-02-09 2019-04-18 ホーランド ブルーアヴュー キッズ リハビリテーション ホスピタル Signal trimming and false positive reduction of post-division swallowing acceleration measurement data
US10702692B2 (en) 2018-03-02 2020-07-07 Aleva Neurotherapeutics Neurostimulation device
TWI669709B (en) * 2018-07-17 2019-08-21 宏碁股份有限公司 Electronic system and audio processing method
EP3745411A1 (en) * 2019-05-27 2020-12-02 Universitat Pompeu Fabra A computer implemented method and computer program products for identifying time-frequency features of physiological events
CN115670398A (en) * 2021-07-27 2023-02-03 华为技术有限公司 Physiological parameter detection method and device
CN114642440B (en) * 2022-05-23 2022-08-12 博睿康科技(常州)股份有限公司 Method for acquiring preset duration of stimulation system, stimulation system and regulation and control method thereof
GB2620384A (en) * 2022-07-01 2024-01-10 Neuronostics Ltd Method and system for estimating dynamic seizure likelihood

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5707334A (en) * 1995-08-21 1998-01-13 Young; Robert B. Method of treating amygdala related transitory disorders
US20030004428A1 (en) * 2001-06-28 2003-01-02 Pless Benjamin D. Seizure sensing and detection using an implantable device
US20040133390A1 (en) * 2002-10-15 2004-07-08 Medtronic, Inc. Synchronization and calibration of clocks for a medical device and calibrated clock
WO2004064918A1 (en) * 2003-01-14 2004-08-05 Department Of Veterans Affairs, Office Of General Counsel Cervical wagal stimulation induced weight loss
US20040230105A1 (en) * 2003-05-15 2004-11-18 Widemed Ltd. Adaptive prediction of changes of physiological/pathological states using processing of biomedical signals
US20060015153A1 (en) * 2004-07-15 2006-01-19 Gliner Bradford E Systems and methods for enhancing or affecting neural stimulation efficiency and/or efficacy
US20060079936A1 (en) * 2003-05-11 2006-04-13 Boveja Birinder R Method and system for altering regional cerebral blood flow (rCBF) by providing complex and/or rectangular electrical pulses to vagus nerve(s), to provide therapy for depression and other medical disorders

Family Cites Families (78)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3498287A (en) 1966-04-28 1970-03-03 Neural Models Ltd Intelligence testing and signal analyzing means and method employing zero crossing detection
US3841309A (en) 1970-12-21 1974-10-15 A Salter Method of analyzing cerebral electrical activity
US4060716A (en) 1975-05-19 1977-11-29 Rockwell International Corporation Method and apparatus for automatic abnormal events monitor in operating plants
US4556063A (en) 1980-10-07 1985-12-03 Medtronic, Inc. Telemetry system for a medical device
US4868773A (en) 1985-03-15 1989-09-19 Purdue Research Foundation Digital filtering by threshold decomposition
JPS61243505A (en) 1985-04-19 1986-10-29 Omron Tateisi Electronics Co Discrete time controller
US5331969A (en) 1985-07-30 1994-07-26 Swinburne Limited Equipment for testing or measuring brain activity
US4663703A (en) 1985-10-02 1987-05-05 Westinghouse Electric Corp. Predictive model reference adaptive controller
US5092343A (en) 1988-02-17 1992-03-03 Wayne State University Waveform analysis apparatus and method using neural network techniques
EP0355506B1 (en) 1988-08-16 1994-12-14 Siemens Aktiengesellschaft Arrangement for measuring local bioelectric currents in biological tissue
US4998051A (en) 1989-03-23 1991-03-05 Matsushita Electric Industrial Co., Ltd. Adaptive control system
US5345535A (en) 1990-04-04 1994-09-06 Doddington George R Speech analysis method and apparatus
EP0524317A4 (en) 1991-02-08 1995-02-15 Tokyo Shibaura Electric Co Model forecasting controller
US5304206A (en) 1991-11-18 1994-04-19 Cyberonics, Inc. Activation techniques for implantable medical device
JP3027047B2 (en) 1992-01-29 2000-03-27 キヤノン株式会社 DTMF signal detection apparatus and method
US5311876A (en) 1992-11-18 1994-05-17 The Johns Hopkins University Automatic detection of seizures using electroencephalographic signals
FR2700632B1 (en) 1993-01-21 1995-03-24 France Telecom Predictive coding-decoding system for a digital speech signal by adaptive transform with nested codes.
GB2279777B (en) 1993-06-30 1997-07-16 West Instr Limited Apparatus for and method of controlling a process
US5349962A (en) 1993-11-30 1994-09-27 University Of Washington Method and apparatus for detecting epileptic seizures
US5519605A (en) 1994-10-24 1996-05-21 Olin Corporation Model predictive control apparatus and method
US6480743B1 (en) 2000-04-05 2002-11-12 Neuropace, Inc. System and method for adaptive brain stimulation
US6473732B1 (en) 1995-10-18 2002-10-29 Motorola, Inc. Signal analyzer and method thereof
US5995868A (en) 1996-01-23 1999-11-30 University Of Kansas System for the prediction, rapid detection, warning, prevention, or control of changes in activity states in the brain of a subject
US6463328B1 (en) 1996-02-02 2002-10-08 Michael Sasha John Adaptive brain stimulation method and system
US6066163A (en) 1996-02-02 2000-05-23 John; Michael Sasha Adaptive brain stimulation method and system
US5857978A (en) 1996-03-20 1999-01-12 Lockheed Martin Energy Systems, Inc. Epileptic seizure prediction by non-linear methods
US5711316A (en) 1996-04-30 1998-01-27 Medtronic, Inc. Method of treating movement disorders by brain infusion
US5694342A (en) 1996-10-24 1997-12-02 The United States Of America As Represented By The Secretary Of The Navy Method for detecting signals in non-Gaussian background clutter
US7630757B2 (en) 1997-01-06 2009-12-08 Flint Hills Scientific Llc System for the prediction, rapid detection, warning, prevention, or control of changes in activity states in the brain of a subject
US6098463A (en) 1997-02-18 2000-08-08 Etymotic Research, Inc. Method and apparatus for measurement of wide dynamic range signals
JP3903588B2 (en) 1997-07-31 2007-04-11 ソニー株式会社 Signal change detection circuit
US6647296B2 (en) 1997-10-27 2003-11-11 Neuropace, Inc. Implantable apparatus for treating neurological disorders
WO1999034865A1 (en) 1998-01-08 1999-07-15 Levin Richard B Eeg based consciousness-alert monitoring system
US6227203B1 (en) 1998-02-12 2001-05-08 Medtronic, Inc. Techniques for controlling abnormal involuntary movements by brain stimulation and drug infusion
US5928272A (en) 1998-05-02 1999-07-27 Cyberonics, Inc. Automatic activation of a neurostimulator device using a detection algorithm based on cardiac activity
AU5900299A (en) 1998-08-24 2000-03-14 Emory University Method and apparatus for predicting the onset of seizures based on features derived from signals indicative of brain activity
US6121817A (en) 1999-01-11 2000-09-19 Omnivision Technologies, Inc. Analog median filter circuit for image processing
US6341236B1 (en) 1999-04-30 2002-01-22 Ivan Osorio Vagal nerve stimulation techniques for treatment of epileptic seizures
US6442506B1 (en) 1999-11-08 2002-08-27 TREVIñO GEORGE Spectrum analysis method and apparatus
US6473639B1 (en) 2000-03-02 2002-10-29 Neuropace, Inc. Neurological event detection procedure using processed display channel based algorithms and devices incorporating these procedures
WO2001075660A1 (en) 2000-04-03 2001-10-11 Flint Hills Scientific, L.L.C. Method, computer program, and system for automated real-time signal analysis for detection, quantification, and prediction of signal changes
US6768969B1 (en) 2000-04-03 2004-07-27 Flint Hills Scientific, L.L.C. Method, computer program, and system for automated real-time signal analysis for detection, quantification, and prediction of signal changes
US6442421B1 (en) 2000-04-27 2002-08-27 Centre National De La Recherche Scientifique Method for the medical monitoring in real time of a patient from the analysis of electroencephalograms to characterize and differentiate between physiological or pathological conditions, and a method for anticipating epileptic seizures
US20020077557A1 (en) 2000-10-31 2002-06-20 Trustmed. Com Corp. Method of periodically or constantly watching a person's blood pressure and system thereof
US7089059B1 (en) 2000-11-03 2006-08-08 Pless Benjamin D Predicting susceptibility to neurological dysfunction based on measured neural electrophysiology
US6594524B2 (en) 2000-12-12 2003-07-15 The Trustees Of The University Of Pennsylvania Adaptive method and apparatus for forecasting and controlling neurological disturbances under a multi-level control
US7299096B2 (en) 2001-03-08 2007-11-20 Northstar Neuroscience, Inc. System and method for treating Parkinson's Disease and other movement disorders
GB0111267D0 (en) 2001-05-05 2001-06-27 Toumaz Technology Ltd Electronic circuit
US20040006264A1 (en) 2001-11-20 2004-01-08 Mojarradi Mohammad M. Neural prosthetic micro system
US20030149456A1 (en) 2002-02-01 2003-08-07 Rottenberg William B. Multi-electrode cardiac lead adapter with multiplexer
WO2004034879A2 (en) 2002-10-15 2004-04-29 Medtronic Inc. Screening techniques for management of a nervous system disorder
EP1558330A4 (en) 2002-10-15 2008-10-01 Medtronic Inc Cycle mode providing redundant back-up to ensure termination of treatment therapy in a medical device system
EP1558121A4 (en) 2002-10-15 2008-10-15 Medtronic Inc Signal quality monitoring and control for a medical device system
EP1558129B1 (en) 2002-10-15 2009-11-25 Medtronic, Inc. Phase shifting of neurological signals in a medical device system
WO2004036372A2 (en) 2002-10-15 2004-04-29 Medtronic Inc. Scoring of sensed neurological signals for use with a medical device system
AU2003301481A1 (en) 2002-10-15 2004-05-04 Medtronic Inc. Channel-selective blanking for a medical device system
AU2003287162A1 (en) 2002-10-15 2004-05-04 Medtronic Inc. Configuring and testing treatment therapy parameters for a medical device system
EP1562674A4 (en) 2002-10-15 2008-10-08 Medtronic Inc Control of treatment therapy during start-up and during operation of a medical device system
AU2003301370A1 (en) 2002-10-15 2004-05-04 Medtronic Inc. Multi-modal operation of a medical device system
US20040138518A1 (en) 2002-10-15 2004-07-15 Medtronic, Inc. Medical device system with relaying module for treatment of nervous system disorders
WO2004034880A2 (en) 2002-10-15 2004-04-29 Medtronic Inc. Timed delay for redelivery of treatment therapy for a medical device system
WO2004034885A2 (en) 2002-10-15 2004-04-29 Medtronic Inc. Signal quality monitoring and control for a medical device system
TWI231673B (en) 2002-11-07 2005-04-21 Realtek Semiconductor Corp A modulator used for network transceiver and method thereof
WO2004043536A1 (en) 2002-11-12 2004-05-27 Neuropace, Inc. System for adaptive brain stimulation
WO2004087256A1 (en) 2003-04-02 2004-10-14 Neurostream Technologies Inc. Implantable nerve signal sensing and stimulation device for treating foot drop and other neurological disorders
NZ527751A (en) 2003-08-22 2006-09-29 Brainz Instr Ltd EEG seizure analysis
CA2454184A1 (en) 2003-12-23 2005-06-23 Andres M. Lozano Method and apparatus for treating neurological disorders by electrical stimulation of the brain
US7215994B2 (en) 2004-02-17 2007-05-08 Instrumentarium Corporation Monitoring the neurological state of a patient
EP1768555A2 (en) * 2004-06-10 2007-04-04 Science Medicus, Inc. Method and system for processing neuro-electrical waveform signals
US7664551B2 (en) 2004-07-07 2010-02-16 Medtronic Transneuronix, Inc. Treatment of the autonomic nervous system
US7890159B2 (en) 2004-09-30 2011-02-15 Cardiac Pacemakers, Inc. Cardiac activation sequence monitoring and tracking
US7526340B2 (en) 2004-10-29 2009-04-28 Medtronic, Inc. Division approximation for implantable medical devices
US8024029B2 (en) 2004-11-02 2011-09-20 Medtronic, Inc. Techniques for user-activated data retention in an implantable medical device
US8958883B2 (en) 2005-04-19 2015-02-17 Pierre-Yves Mueller Electrical stimulation device and method for therapeutic treatment and pain management
US7761146B2 (en) 2006-04-21 2010-07-20 Medtronic, Inc. Method and apparatus for detection of nervous system disorders
US8165683B2 (en) 2006-04-21 2012-04-24 Medtronic, Inc. Method and apparatus for detection of nervous system disorders
US7764989B2 (en) 2006-04-21 2010-07-27 Medtronic, Inc. Method and apparatus for detection of nervous system disorders
US7761145B2 (en) 2006-04-21 2010-07-20 Medtronic, Inc. Method and apparatus for detection of nervous system disorders

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5707334A (en) * 1995-08-21 1998-01-13 Young; Robert B. Method of treating amygdala related transitory disorders
US20030004428A1 (en) * 2001-06-28 2003-01-02 Pless Benjamin D. Seizure sensing and detection using an implantable device
US20040133390A1 (en) * 2002-10-15 2004-07-08 Medtronic, Inc. Synchronization and calibration of clocks for a medical device and calibrated clock
WO2004064918A1 (en) * 2003-01-14 2004-08-05 Department Of Veterans Affairs, Office Of General Counsel Cervical wagal stimulation induced weight loss
US20060079936A1 (en) * 2003-05-11 2006-04-13 Boveja Birinder R Method and system for altering regional cerebral blood flow (rCBF) by providing complex and/or rectangular electrical pulses to vagus nerve(s), to provide therapy for depression and other medical disorders
US20040230105A1 (en) * 2003-05-15 2004-11-18 Widemed Ltd. Adaptive prediction of changes of physiological/pathological states using processing of biomedical signals
US20060015153A1 (en) * 2004-07-15 2006-01-19 Gliner Bradford E Systems and methods for enhancing or affecting neural stimulation efficiency and/or efficacy

Also Published As

Publication number Publication date
US20080046024A1 (en) 2008-02-21
WO2007124190A3 (en) 2008-05-08
US7979130B2 (en) 2011-07-12
US20070250133A1 (en) 2007-10-25
US8527039B2 (en) 2013-09-03
EP2012662A2 (en) 2009-01-14
EP2010051A2 (en) 2009-01-07
US20110263999A1 (en) 2011-10-27
WO2007124270A2 (en) 2007-11-01
WO2007124190A2 (en) 2007-11-01
US8165683B2 (en) 2012-04-24

Similar Documents

Publication Publication Date Title
WO2007124270A3 (en) Method and apparatus for detection of nervous system disorders
WO2007124194A3 (en) Method and apparatus for detection of nervous system disorders
WO2007143234A3 (en) Method and apparatus for detection of nervous system disorders
ATE525954T1 (en) METHOD AND DEVICE FOR DETECTING DISORDERS OF THE NERVOUS SYSTEM
WO2010002936A3 (en) Systems, methods and devices for paired plasticity
WO2008039921A3 (en) Apparatus and method for treating obstructive sleep apnea
WO2008030344A3 (en) Implantable apparatus for endolymphatic drug delivery
WO2006094015A3 (en) Method of treating depression, mood disorders and anxiety disorders using neuromodulation
WO2006094072A3 (en) Method of treating cognitive disorders using neuromodulation
WO2010062622A3 (en) Selective stimulation systems and signal parameters for medical conditions
WO2008048471A3 (en) Obstructive sleep apnea treatment devices, systems and methods
MX2019005130A (en) Treatment of genotyped diabetic patients with dpp-iv inhibitors such as linagliptin.
WO2010132816A3 (en) Methods, systems and devices for neuromodulating spinal anatomy
WO2007048000A3 (en) Neural stimulation system and optical monitoring systems and methods
WO2007146517A3 (en) System for neural stimulation via lymphatic vessel
WO2010075319A3 (en) Method and apparatus for limiting growth of eye length
WO2011008749A3 (en) Physiological vibration detection in an implanted medical device
MX2015007714A (en) Gpc3-targeted therapeutic agent for administration to patients for whom gpc3-targeted therapeutic agent therapy is effective.
WO2009059371A3 (en) Systems, methods and devices for circulatory access
WO2006127007A3 (en) Methods of using adipose tissue-derived cells in the treatment of cardiovascular conditions
WO2009140636A3 (en) Method and apparatus for sensing respiratory pressure in an implantable stimulation system
WO2006138359A3 (en) Method for detecting the disconnection of an extracorporeal device using a patient's endogenous electrical voltages
WO2007002927A3 (en) Imaging geometry
WO2007089394A3 (en) Controlling neuromodulation using stimulus modalities
WO2009105473A3 (en) Methods and devices for follow-up care and treatment of a pneumostoma

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 07760403

Country of ref document: EP

Kind code of ref document: A2

NENP Non-entry into the national phase

Ref country code: DE

WWE Wipo information: entry into national phase

Ref document number: 2007760403

Country of ref document: EP