WO2007131255A8 - Elektronische biosensoranordnung - Google Patents

Elektronische biosensoranordnung

Info

Publication number
WO2007131255A8
WO2007131255A8 PCT/AT2007/000233 AT2007000233W WO2007131255A8 WO 2007131255 A8 WO2007131255 A8 WO 2007131255A8 AT 2007000233 W AT2007000233 W AT 2007000233W WO 2007131255 A8 WO2007131255 A8 WO 2007131255A8
Authority
WO
WIPO (PCT)
Prior art keywords
csensor
earth
capacitors
driven
control logic
Prior art date
Application number
PCT/AT2007/000233
Other languages
English (en)
French (fr)
Other versions
WO2007131255A1 (de
Inventor
Christa Noehammer
Meneses Rocha Daniel Pau Wiese
Vroonhoven Caspar Van
Michael Johannes Vellekoop
Original Assignee
Arc Austrian Res Centers Gmbh
Christa Noehammer
Meneses Rocha Daniel Pau Wiese
Vroonhoven Caspar Van
Michael Johannes Vellekoop
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Arc Austrian Res Centers Gmbh, Christa Noehammer, Meneses Rocha Daniel Pau Wiese, Vroonhoven Caspar Van, Michael Johannes Vellekoop filed Critical Arc Austrian Res Centers Gmbh
Priority to EP07718445A priority Critical patent/EP2018438A1/de
Priority to US12/300,978 priority patent/US8043563B2/en
Priority to CA002652407A priority patent/CA2652407A1/en
Publication of WO2007131255A1 publication Critical patent/WO2007131255A1/de
Publication of WO2007131255A8 publication Critical patent/WO2007131255A8/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28—Electrolytic cell components
    • G01N27/30—Electrodes, e.g. test electrodes; Half-cells
    • G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
    • G01N27/3275—Sensing specific biomolecules, e.g. nucleic acid strands, based on an electrode surface reaction
    • G01N27/3276—Sensing specific biomolecules, e.g. nucleic acid strands, based on an electrode surface reaction being a hybridisation with immobilised receptors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means

Abstract

Elektronische Biosensoranordnung (1) mit einem Aufnahmebereich (2) für biologisches Material, dem eine Sensorelektrodenanordnung (3) mit kammartig ineinandergreifenden Sensorelektroden (3a, 3b) zugeordnet ist, an die ein Messkreis (5) zur Messung einer von biologischem Material beeinf lussten elektrischen Messgröße an den Sensorelektroden (3a, 3b) anschaltbar ist, wobei die Sensorelektroden (3a, 3b) eine Vielzahl von Sensorkondensatoren (Csensor,1 bis Csensor,N) bilden, denen von einer Steuerlogik (8) angesteuerte elektronische Schaltmittel (S2, 1 bis S2,N) zum Verbinden mit Masse oder mit einer eine Messspannung (Vdrive) führenden Spannungsquelle zugeordnet sind, mit einem Referenzkondensator (Cref), dem ebenfalls ein von der Steuerlogik (8) angesteuertes Schaltmittel (S1) zum wahlweisen Verbinden mit Masse oder mit der Messspannung (Vdrive) zugeordnet ist, wobei die Kondensatoren (Cref, Csensor,1 - Csensor,N) andererseits in einem Knoten (A) zusammengeführt sind, der mit einem Eingang (-) eines Differenzverstärkers (10) verbunden ist, und mit dem weiters Messkondensatoren (C0 bis C5) mit binär gewichteten Kapazitäten (Cmin bis 32Cmin) zur Bildung einer SAR-Vergleichseinheit verbunden sind, welche andererseits über von der Steuerlogik (8) angesteuerte Schaltmittel (S3,0 bis S3, 5) zwecks Ladungsdifferenzbildung für die SAR-Wandlung selektiv mit einer Spannungsquelle (Varray) oder mit Masse verbindbar sind.
PCT/AT2007/000233 2006-05-15 2007-05-15 Elektronische biosensoranordnung WO2007131255A1 (de)

Priority Applications (3)

Application Number Priority Date Filing Date Title
EP07718445A EP2018438A1 (de) 2006-05-15 2007-05-15 Elektronische biosensoranordnunq
US12/300,978 US8043563B2 (en) 2006-05-15 2007-05-15 Electronic biosensor arrangement
CA002652407A CA2652407A1 (en) 2006-05-15 2007-05-15 Electronic biosensor arrangement

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AT0083006A AT503742B8 (de) 2006-05-15 2006-05-15 Elektronische biosensoranordnung
ATA830/2006 2006-05-15

Publications (2)

Publication Number Publication Date
WO2007131255A1 WO2007131255A1 (de) 2007-11-22
WO2007131255A8 true WO2007131255A8 (de) 2008-02-28

Family

ID=38268834

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/AT2007/000233 WO2007131255A1 (de) 2006-05-15 2007-05-15 Elektronische biosensoranordnung

Country Status (7)

Country Link
US (1) US8043563B2 (de)
EP (1) EP2018438A1 (de)
KR (1) KR20090056932A (de)
CN (1) CN101512015A (de)
AT (1) AT503742B8 (de)
CA (1) CA2652407A1 (de)
WO (1) WO2007131255A1 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3074169A1 (en) * 2017-09-29 2019-04-04 Boehringer Ingelheim Vetmedica Gmbh Testing and calibration of a circuit arrangement

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4860232A (en) * 1987-04-22 1989-08-22 Massachusetts Institute Of Technology Digital technique for precise measurement of variable capacitance
US5027814A (en) * 1989-05-19 1991-07-02 Ventritex, Inc. Implantable medical device employing an improved waveform digitization network
US5235333A (en) * 1992-03-05 1993-08-10 Burr-Brown Corporation Hysteresis-insensitive single-comparator successive approximation analog-to-digital converter
US5920275A (en) * 1996-09-09 1999-07-06 Iowa State University Research Foundation, Inc. Analog-to-digital converter using weighted capacitor array and interpolating comparator
US6225678B1 (en) * 1998-12-23 2001-05-01 Microchip Technology Incorporated Layout technique for a matching capacitor array using a continuous top electrode
US20030226768A1 (en) * 2000-03-30 2003-12-11 Franz Hoffman Method for detecting macromolecular biopolymers by means of an electrode arrangement
US7413859B2 (en) * 2001-11-14 2008-08-19 Siemens Aktiengesellschaft Method and biosensors for detecting macromolecular biopolymers
DE10204652B4 (de) * 2002-02-05 2004-07-22 Infineon Technologies Ag Schaltkreis-Anordnung, elektrochemischer Sensor, Sensor-Anordnung und Verfahren zum Verarbeiten eines über eine Sensor-Elektrode bereitgestellten Stromsignals
JP2003258639A (ja) * 2002-02-27 2003-09-12 Nec Microsystems Ltd アナログ−ディジタル変換器
US6600437B1 (en) * 2002-04-01 2003-07-29 Stmicroelectronics S.R.L. High resolution, high speed, low power switched capacitor digital to analog converter
DE10224567B4 (de) * 2002-06-03 2014-10-23 Boehringer Ingelheim Vetmedica Gmbh Sensor-Anordnung und Verfahren zum Betreiben einer Sensor-Anordnung
US6714151B2 (en) * 2002-06-21 2004-03-30 Fujitsu Limited A/D converter
DE10259819B4 (de) 2002-12-19 2006-07-13 Siemens Ag Verfahren zur PCR-Amplifikation und Detektion von Nucleotidsequenzen
DE10328136A1 (de) * 2003-06-23 2005-01-27 Infineon Technologies Ag Sensor-Element, Sensor-Array und Verfahren zum Erfassen von in einem Analyten möglicherweise enthaltenen Partikeln
DE102004045210A1 (de) 2004-09-17 2006-04-06 Infineon Technologies Ag Sensor-Anordnung und Verfahren zum Ermitteln eines Sensorereignisses

Also Published As

Publication number Publication date
KR20090056932A (ko) 2009-06-03
US20090206847A1 (en) 2009-08-20
AT503742B8 (de) 2011-08-15
WO2007131255A1 (de) 2007-11-22
AT503742A1 (de) 2007-12-15
CA2652407A1 (en) 2007-11-22
AT503742B1 (de) 2011-06-15
US8043563B2 (en) 2011-10-25
EP2018438A1 (de) 2009-01-28
CN101512015A (zh) 2009-08-19

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