WO2007149868A3 - Controlled release encapsulated anti-bacterial and anti-inflammatory nanoparticles - Google Patents

Controlled release encapsulated anti-bacterial and anti-inflammatory nanoparticles Download PDF

Info

Publication number
WO2007149868A3
WO2007149868A3 PCT/US2007/071580 US2007071580W WO2007149868A3 WO 2007149868 A3 WO2007149868 A3 WO 2007149868A3 US 2007071580 W US2007071580 W US 2007071580W WO 2007149868 A3 WO2007149868 A3 WO 2007149868A3
Authority
WO
WIPO (PCT)
Prior art keywords
nanoparticles
inflammatory
bacterial
controlled release
release encapsulated
Prior art date
Application number
PCT/US2007/071580
Other languages
French (fr)
Other versions
WO2007149868A2 (en
Inventor
Jenny Kim
Adam Friedman
Robert Modlin
Original Assignee
Univ California
Jenny Kim
Adam Friedman
Robert Modlin
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ California, Jenny Kim, Adam Friedman, Robert Modlin filed Critical Univ California
Priority to US12/303,166 priority Critical patent/US20110135742A1/en
Publication of WO2007149868A2 publication Critical patent/WO2007149868A2/en
Publication of WO2007149868A3 publication Critical patent/WO2007149868A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/513—Organic macromolecular compounds; Dendrimers
    • A61K9/5161—Polysaccharides, e.g. alginate, chitosan, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Abstract

This invention pertains to the formulation of nanoparticles that have intrinsic antimicrobial and anti-inflammatory activity. The nanoparticles can be impregnated with one or more therapeutic agents and thereby enhance the antimicrobial and/or anti-inflammatory activity of such agents, and also other properties that the therapeutic agents provide.
PCT/US2007/071580 2006-06-20 2007-06-19 Controlled release encapsulated anti-bacterial and anti-inflammatory nanoparticles WO2007149868A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
US12/303,166 US20110135742A1 (en) 2006-06-20 2007-06-19 Controlled release encapsulated anti-bacterial and anti-inflammatory nanoparticles

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US81528606P 2006-06-20 2006-06-20
US60/815,286 2006-06-20

Publications (2)

Publication Number Publication Date
WO2007149868A2 WO2007149868A2 (en) 2007-12-27
WO2007149868A3 true WO2007149868A3 (en) 2008-07-03

Family

ID=38834319

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2007/071580 WO2007149868A2 (en) 2006-06-20 2007-06-19 Controlled release encapsulated anti-bacterial and anti-inflammatory nanoparticles

Country Status (2)

Country Link
US (1) US20110135742A1 (en)
WO (1) WO2007149868A2 (en)

Families Citing this family (61)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9486408B2 (en) 2005-12-01 2016-11-08 University Of Massachusetts Lowell Botulinum nanoemulsions
JP5292304B2 (en) 2006-12-01 2013-09-18 アンテリオス， インコーポレイテッド Peptide nanoparticles and uses thereof
BRPI0719756A2 (en) 2006-12-01 2014-01-21 Anterios Inc Amphiphilic Nanoparticles
US10016451B2 (en) 2007-05-31 2018-07-10 Anterios, Inc. Nucleic acid nanoparticles and uses therefor
US9044477B2 (en) * 2007-12-12 2015-06-02 Allergan, Inc. Botulinum toxin formulation
ES2448572T3 (en) * 2008-05-29 2014-03-14 Basf Se Antimicrobial composition containing antimicrobials covalently bound with an interpenetrating polyurethane-silicon network
EP2303026B1 (en) 2008-06-17 2020-09-09 Brigham Young University Cationic steroid antimicrobial diagnostic, detection, screening and imaging methods
EP2116237A1 (en) 2008-08-05 2009-11-11 Polichem SA Compositions for treating rosacea comprising chitosan and a dicarboxylic acid
US20100111857A1 (en) 2008-10-31 2010-05-06 Boyden Edward S Compositions and methods for surface abrasion with frozen particles
US8545856B2 (en) 2008-10-31 2013-10-01 The Invention Science Fund I, Llc Compositions and methods for delivery of frozen particle adhesives
US9050070B2 (en) 2008-10-31 2015-06-09 The Invention Science Fund I, Llc Compositions and methods for surface abrasion with frozen particles
US8731840B2 (en) 2008-10-31 2014-05-20 The Invention Science Fund I, Llc Compositions and methods for therapeutic delivery with frozen particles
US8221480B2 (en) 2008-10-31 2012-07-17 The Invention Science Fund I, Llc Compositions and methods for biological remodeling with frozen particle compositions
US9060934B2 (en) 2008-10-31 2015-06-23 The Invention Science Fund I, Llc Compositions and methods for surface abrasion with frozen particles
US8788211B2 (en) 2008-10-31 2014-07-22 The Invention Science Fund I, Llc Method and system for comparing tissue ablation or abrasion data to data related to administration of a frozen particle composition
US8409376B2 (en) 2008-10-31 2013-04-02 The Invention Science Fund I, Llc Compositions and methods for surface abrasion with frozen particles
US8798932B2 (en) 2008-10-31 2014-08-05 The Invention Science Fund I, Llc Frozen compositions and methods for piercing a substrate
US8721583B2 (en) 2008-10-31 2014-05-13 The Invention Science Fund I, Llc Compositions and methods for surface abrasion with frozen particles
US8545855B2 (en) 2008-10-31 2013-10-01 The Invention Science Fund I, Llc Compositions and methods for surface abrasion with frozen particles
US8762067B2 (en) 2008-10-31 2014-06-24 The Invention Science Fund I, Llc Methods and systems for ablation or abrasion with frozen particles and comparing tissue surface ablation or abrasion data to clinical outcome data
US9060931B2 (en) 2008-10-31 2015-06-23 The Invention Science Fund I, Llc Compositions and methods for delivery of frozen particle adhesives
US8731841B2 (en) 2008-10-31 2014-05-20 The Invention Science Fund I, Llc Compositions and methods for therapeutic delivery with frozen particles
US8603495B2 (en) 2008-10-31 2013-12-10 The Invention Science Fund I, Llc Compositions and methods for biological remodeling with frozen particle compositions
US9072688B2 (en) 2008-10-31 2015-07-07 The Invention Science Fund I, Llc Compositions and methods for therapeutic delivery with frozen particles
US8545857B2 (en) 2008-10-31 2013-10-01 The Invention Science Fund I, Llc Compositions and methods for administering compartmentalized frozen particles
US9072799B2 (en) 2008-10-31 2015-07-07 The Invention Science Fund I, Llc Compositions and methods for surface abrasion with frozen particles
US9050317B2 (en) 2008-10-31 2015-06-09 The Invention Science Fund I, Llc Compositions and methods for therapeutic delivery with frozen particles
US8603494B2 (en) 2008-10-31 2013-12-10 The Invention Science Fund I, Llc Compositions and methods for administering compartmentalized frozen particles
US9060926B2 (en) 2008-10-31 2015-06-23 The Invention Science Fund I, Llc Compositions and methods for therapeutic delivery with frozen particles
US20100111845A1 (en) * 2008-10-31 2010-05-06 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Compositions and methods for therapeutic delivery with frozen particles
US8551505B2 (en) 2008-10-31 2013-10-08 The Invention Science Fund I, Llc Compositions and methods for therapeutic delivery with frozen particles
US8793075B2 (en) 2008-10-31 2014-07-29 The Invention Science Fund I, Llc Compositions and methods for therapeutic delivery with frozen particles
US8725420B2 (en) 2008-10-31 2014-05-13 The Invention Science Fund I, Llc Compositions and methods for surface abrasion with frozen particles
US8485861B2 (en) 2008-10-31 2013-07-16 The Invention Science Fund I, Llc Systems, devices, and methods for making or administering frozen particles
US20150079160A1 (en) * 2009-06-02 2015-03-19 Concept Medical Research Private Limited Non-implantable medical device coated with nano-carriers for delivering one or more drugs to a body site
JP6131194B2 (en) * 2011-01-24 2017-05-17 アンテリオス， インコーポレイテッド Empty nanoparticle composition and use thereof for treating dermatological symptoms
KR20140063616A (en) 2011-07-20 2014-05-27 브라이엄 영 유니버시티 Hydrophobic ceragenin compounds and devices incorporating same
WO2013078252A1 (en) 2011-11-22 2013-05-30 Qd Vision, Inc. Quantum dot-containing compositions including an emission stabilizer, products including same, and method
EP3225113B1 (en) 2012-05-02 2020-09-02 Brigham Young University Methods for making ceragenin particulate materials
TWI455725B (en) * 2012-05-31 2014-10-11 Univ Chia Nan Pharm & Sciency Chitosan microcapsules and method of making the same
CN105451742B (en) 2013-01-07 2021-04-06 布莱阿姆青年大学 Methods for reducing cell proliferation and treating certain diseases
WO2014164418A1 (en) 2013-03-11 2014-10-09 North Carolina State University Functionalized environmentally benign nanoparticles
US10568893B2 (en) 2013-03-15 2020-02-25 Brigham Young University Methods for treating inflammation, autoimmune disorders and pain
CA2907082C (en) 2013-03-15 2021-05-04 Brigham Young University Methods for treating inflammation, autoimmune disorders and pain
US11524015B2 (en) 2013-03-15 2022-12-13 Brigham Young University Methods for treating inflammation, autoimmune disorders and pain
US11690855B2 (en) 2013-10-17 2023-07-04 Brigham Young University Methods for treating lung infections and inflammation
US20150203527A1 (en) 2014-01-23 2015-07-23 Brigham Young University Cationic steroidal antimicrobials
CA2844321C (en) 2014-02-27 2021-03-16 Brigham Young University Cationic steroidal antimicrobial compounds
US10220045B2 (en) 2014-03-13 2019-03-05 Brigham Young University Compositions and methods for forming stabilized compositions with reduced CSA agglomeration
US9931350B2 (en) 2014-03-14 2018-04-03 Brigham Young University Anti-infective and osteogenic compositions and methods of use
US10238665B2 (en) 2014-06-26 2019-03-26 Brigham Young University Methods for treating fungal infections
US10441595B2 (en) 2014-06-26 2019-10-15 Brigham Young University Methods for treating fungal infections
US10227376B2 (en) 2014-08-22 2019-03-12 Brigham Young University Radiolabeled cationic steroid antimicrobials and diagnostic methods
US10155788B2 (en) 2014-10-07 2018-12-18 Brigham Young University Cationic steroidal antimicrobial prodrug compositions and uses thereof
US10370403B2 (en) 2015-04-22 2019-08-06 Brigham Young University Methods for the synthesis of ceragenins
US10226550B2 (en) * 2016-03-11 2019-03-12 Brigham Young University Cationic steroidal antimicrobial compositions for the treatment of dermal tissue
CN117731591A (en) 2016-11-21 2024-03-22 艾里奥治疗公司 Transdermal delivery of large agents
US10959433B2 (en) 2017-03-21 2021-03-30 Brigham Young University Use of cationic steroidal antimicrobials for sporicidal activity
WO2021076020A2 (en) * 2019-10-14 2021-04-22 Андрей Михайлович ГАПОНОВ Pharmaceutical composition for the treatment and prophylaxis of infectious inflammatory diseases
WO2023043813A1 (en) * 2021-09-14 2023-03-23 The American University In Cairo Nanoguard
CN115230264B (en) * 2022-07-11 2023-06-27 北京科技大学 Intelligent controlled release fresh-keeping composite film capable of preventing contact surface from changing color

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030099718A1 (en) * 2001-04-23 2003-05-29 Burrell Robert Edward Treatment of mucosal membranes
US20050281886A1 (en) * 2004-05-06 2005-12-22 Ivrea Pharmaceuticals, Inc. Particles for the delivery of active agents

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4895724A (en) * 1985-06-07 1990-01-23 Pfizer Inc. Chitosan compositions for controlled and prolonged release of macromolecules
US4946870A (en) * 1986-06-06 1990-08-07 Union Carbide Chemicals And Plastics Company Inc. Delivery systems for pharmaceutical or therapeutic actives
US6096344A (en) * 1995-07-28 2000-08-01 Advanced Polymer Systems, Inc. Bioerodible porous compositions
US6649192B2 (en) * 1996-07-29 2003-11-18 Universidade De Santiago De Compostela Application of nanoparticles based on hydrophilic polymers as pharmaceutical forms
US6197322B1 (en) * 1997-12-23 2001-03-06 Kimberly-Clark Worldwide, Inc. Antimicrobial structures
WO1999045784A1 (en) * 1998-03-12 1999-09-16 Oji Paper Co., Ltd. Bactericides
US6734210B2 (en) * 2000-02-24 2004-05-11 Rolland F. Hebert Therapeutically improved salts of azelaic acid
WO2001064164A2 (en) * 2000-02-28 2001-09-07 Genesegues, Inc. Nanocapsule encapsulation system and method
US6451773B1 (en) * 2000-03-31 2002-09-17 Cognis Corporation Chitosan formulation with azelaic acid and other actives for the treatment of acne
ES2221530B1 (en) * 2002-07-19 2006-02-16 Universidad De Santiago De Compostela NANOPARTICLES FOR THE ADMINISTRATION OF ACTIVE INGREDIENTS, PROCEDURE FOR THE ELABORATION OF SUCH PARTICLES AND COMPOSITION THAT CONTAIN THEM.
EP1562543A1 (en) * 2002-11-21 2005-08-17 J.P.M.E.D. Ltd. Compositions for treating infected skin and mucous membrane comprising an anti-microbial agent and an essential oil
US20040156873A1 (en) * 2003-02-10 2004-08-12 Gupta Shyam K. Topically Bioavailable Acne and Rosacea Treatment Compositions
JP2006525333A (en) * 2003-05-02 2006-11-09 ザ ボード オブ トラスティーズ オブ ザ ユニバーシティ オブ イリノイ Biodegradable nanoparticles incorporating highly hydrophilic and positively charged drugs
US8043632B2 (en) * 2003-08-18 2011-10-25 E. I. Du Pont De Nemours And Company Process for making antimicrobial articles by reacting chitosan with amino-reactive polymer surfaces
US20060141046A1 (en) * 2004-05-06 2006-06-29 Ivrea Pharmaceuticals, Inc. Particles for the delivery of active agents

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030099718A1 (en) * 2001-04-23 2003-05-29 Burrell Robert Edward Treatment of mucosal membranes
US20050281886A1 (en) * 2004-05-06 2005-12-22 Ivrea Pharmaceuticals, Inc. Particles for the delivery of active agents

Also Published As

Publication number Publication date
WO2007149868A2 (en) 2007-12-27
US20110135742A1 (en) 2011-06-09

Similar Documents

Publication Publication Date Title
WO2007149868A3 (en) Controlled release encapsulated anti-bacterial and anti-inflammatory nanoparticles
WO2011030158A3 (en) Antimicrobial composition
WO2009064767A3 (en) Bactericidal nanofibers, and methods of use thereof
HK1225961A1 (en) Compositions and methods for the treatment or prevention of staphylococcus aureus infections and for the eradication or reduction of staphylococcus aureus on surfaces
WO2008085578A3 (en) Anti-microbial compositions and devices and methods of using the same
WO2009121970A3 (en) Coating material
WO2008009379A3 (en) Active ingredient combinations having insecticide and acaricide properties
WO2010062396A3 (en) Virus like particle compositions and methods of use
EP2687287A3 (en) Delivery particles
EP2687590A3 (en) Delivery particles
EP2160152A4 (en) Combined fibrinolytic and antimicrobial catheter and uses thereof
WO2006099232A3 (en) Antimicrobial pet wipes
WO2010079468A3 (en) Delivery particle
WO2008131089A3 (en) Reduction of infection associated with medical device
WO2008084495A3 (en) Novel agricultural composition
WO2007109330A3 (en) S1p receptor modulating compounds
IL213489A0 (en) Compositions and methods for the treatment of the prevention of e. coli infections and for the eradication or reduction of e. coli surfaces
MX2012000827A (en) Particles incorporating antimicrobial agents.
WO2010059366A3 (en) Antimicrobial foamable soaps
WO2007126824A3 (en) Methods and systems for sterilization
WO2008104310A3 (en) Antimicrobial compositions
WO2011142858A3 (en) Chlorotoxin variants, conjugates, and methods for their use
WO2006089665A3 (en) Active ingredient combinations having insecticide and acaricide properties
PT3001905T (en) Active agent combinations with insecticides and acaricide properties
WO2009141633A3 (en) Polysaccharide nanofibres having antimicrobial properties

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 07798767

Country of ref document: EP

Kind code of ref document: A2

NENP Non-entry into the national phase

Ref country code: DE

NENP Non-entry into the national phase

Ref country code: RU

122 Ep: pct application non-entry in european phase

Ref document number: 07798767

Country of ref document: EP

Kind code of ref document: A2

WWE Wipo information: entry into national phase

Ref document number: 12303166

Country of ref document: US