WO2008008330A3 - Deuterated ocular solutions for ltk and other surgical eye procedures - Google Patents

Deuterated ocular solutions for ltk and other surgical eye procedures Download PDF

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Publication number
WO2008008330A3
WO2008008330A3 PCT/US2007/015718 US2007015718W WO2008008330A3 WO 2008008330 A3 WO2008008330 A3 WO 2008008330A3 US 2007015718 W US2007015718 W US 2007015718W WO 2008008330 A3 WO2008008330 A3 WO 2008008330A3
Authority
WO
WIPO (PCT)
Prior art keywords
cornea
deuterated
window
ocular
eye
Prior art date
Application number
PCT/US2007/015718
Other languages
French (fr)
Other versions
WO2008008330B1 (en
WO2008008330A2 (en
Inventor
Michael J Berry
Original Assignee
Ntk Entpr Inc
Michael J Berry
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ntk Entpr Inc, Michael J Berry filed Critical Ntk Entpr Inc
Publication of WO2008008330A2 publication Critical patent/WO2008008330A2/en
Publication of WO2008008330A3 publication Critical patent/WO2008008330A3/en
Publication of WO2008008330B1 publication Critical patent/WO2008008330B1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/007—Methods or devices for eye surgery
    • A61F9/008—Methods or devices for eye surgery using laser
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/007—Methods or devices for eye surgery
    • A61F9/008—Methods or devices for eye surgery using laser
    • A61F2009/00853—Laser thermal keratoplasty or radial keratotomy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/007—Methods or devices for eye surgery
    • A61F9/008—Methods or devices for eye surgery using laser
    • A61F2009/00861—Methods or devices for eye surgery using laser adapted for treatment at a particular location
    • A61F2009/00872—Cornea
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/007—Methods or devices for eye surgery
    • A61F9/008—Methods or devices for eye surgery using laser
    • A61F9/009—Auxiliary devices making contact with the eyeball and coupling in laser light, e.g. goniolenses

Abstract

A deuterated ocular solution is applied (1204) to an eye. The deuterated ocular solution includes deuterated water and one or more ocular drugs (such as proparacaine). A protective corneal device (102) is applied (1206) to a cornea of the eye. The device (102) includes a window (210) configured to contact at least a portion of the cornea. At least part of the cornea is irradiated (1208) using light energy that passes through the window (210) during a cornea reshaping procedure, where the window (210) is substantially transparent to the light energy. The window (210) of the protective corneal device (102) and the deuterated ocular solution may prevent clinically significant damage to a corneal epithelium of the cornea during the cornea reshaping procedure, such as by preventing a temperature of the corneal epithelium from exceeding approximately 70°C during the cornea reshaping procedure. This may help to avoid a wound healing response in the eye and an associated regression of refractive correction.
PCT/US2007/015718 2006-07-12 2007-07-10 Deuterated ocular solutions for ltk and other surgical eye procedures WO2008008330A2 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US83029206P 2006-07-12 2006-07-12
US60/830,292 2006-07-12
US11/825,816 US7691099B2 (en) 2006-07-12 2007-07-09 Deuterated ocular solutions for LTK and other surgical eye procedures
US11/825,816 2007-07-09

Publications (3)

Publication Number Publication Date
WO2008008330A2 WO2008008330A2 (en) 2008-01-17
WO2008008330A3 true WO2008008330A3 (en) 2008-10-23
WO2008008330B1 WO2008008330B1 (en) 2008-12-18

Family

ID=38923829

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2007/015718 WO2008008330A2 (en) 2006-07-12 2007-07-10 Deuterated ocular solutions for ltk and other surgical eye procedures

Country Status (2)

Country Link
US (1) US7691099B2 (en)
WO (1) WO2008008330A2 (en)

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WO2010039117A1 (en) * 2008-09-11 2010-04-08 Avedro, Inc. Eye therapy system
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US20120203161A1 (en) * 2009-08-12 2012-08-09 Seros Medical, Llc Deuterated water and riboflavin solution for extending singlet oxygen lifetimes in treatment of ocular tissue and method of use
JP5506504B2 (en) * 2010-03-31 2014-05-28 キヤノン株式会社 Imaging apparatus and imaging method
US9211214B2 (en) * 2012-03-21 2015-12-15 Valeant Pharmaceuticals International, Inc Photodynamic therapy laser
US9214043B2 (en) * 2013-03-04 2015-12-15 Here Global B.V. Gesture based map annotation
WO2014145517A1 (en) * 2013-03-15 2014-09-18 Michael Berry Systems and devices for shaping human cornea and methods of use thereof
US10231872B2 (en) 2014-02-28 2019-03-19 Excel-Lens, Inc. Laser assisted cataract surgery
US10206817B2 (en) 2014-02-28 2019-02-19 Excel-Lens, Inc. Laser assisted cataract surgery
US10327951B2 (en) 2014-02-28 2019-06-25 Excel-Lens, Inc. Laser assisted cataract surgery
US9820886B2 (en) 2014-02-28 2017-11-21 Excel-Lens, Inc. Laser assisted cataract surgery
WO2016172712A2 (en) 2015-04-23 2016-10-27 Sydnexis, Inc. Ophthalmic composition
US9421199B2 (en) 2014-06-24 2016-08-23 Sydnexis, Inc. Ophthalmic composition
US11382909B2 (en) 2014-09-05 2022-07-12 Sydnexis, Inc. Ophthalmic composition
CN107847432A (en) * 2015-05-29 2018-03-27 西德奈克西斯公司 D2The stabilized pharmaceutical preparations of O
US10219948B2 (en) 2016-02-24 2019-03-05 Perfect Ip, Llc Ophthalmic laser treatment system and method
MX2020005217A (en) * 2017-11-21 2020-11-24 Sydnexis Inc Ophthalmic composition and delivery device thereof.
WO2019116283A1 (en) * 2017-12-12 2019-06-20 Novartis Ag Surgical probe with shape-memory material
CN111787879B (en) * 2018-03-01 2023-09-15 巴伊兰大学 System, method and material composition for correcting eye condition
ES2935513T3 (en) 2018-07-19 2023-03-07 Alcon Inc Ophthalmic surgical system with radial repulsion magnetic bearing for self-alignment of optical elements
US20200107953A1 (en) * 2018-10-09 2020-04-09 Avedro, Inc. Photoactivation systems and methods for corneal cross-linking treatments

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Also Published As

Publication number Publication date
US20080027418A1 (en) 2008-01-31
WO2008008330B1 (en) 2008-12-18
US7691099B2 (en) 2010-04-06
WO2008008330A2 (en) 2008-01-17

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