WO2008027402A3 - Brachytherapy devices and related methods and computer program products - Google Patents
Brachytherapy devices and related methods and computer program products Download PDFInfo
- Publication number
- WO2008027402A3 WO2008027402A3 PCT/US2007/018951 US2007018951W WO2008027402A3 WO 2008027402 A3 WO2008027402 A3 WO 2008027402A3 US 2007018951 W US2007018951 W US 2007018951W WO 2008027402 A3 WO2008027402 A3 WO 2008027402A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- radiation profile
- computer program
- program products
- related methods
- spatial
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0069—Devices for implanting pellets, e.g. markers or solid medicaments
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
- A61N5/1001—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy using radiation sources introduced into or applied onto the body; brachytherapy
- A61N5/1027—Interstitial radiation therapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
- A61N5/1001—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy using radiation sources introduced into or applied onto the body; brachytherapy
- A61N2005/1019—Sources therefor
- A61N2005/1023—Means for creating a row of seeds, e.g. spacers
Abstract
A low-dose-rate (LDR) brachytherapy device having a spatiotemporal radiation profile includes an elongated body having a radioactive material in a spatial pattern to provide a spatial radiation profile with a radiation intensity that varies along a length of the elongated body. The radioactive material includes at least first and second radioisotopes having at least first and second respective decay profiles that together provide a temporal radiation profile that is different from the first and second decay profiles. The spatial radiation profile and the temporal radiation profile form a net spatiotemporal radiation profile configured to provide a radiotherapy plan for a patient.
Applications Claiming Priority (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US82381406P | 2006-08-29 | 2006-08-29 | |
US60/823,814 | 2006-08-29 | ||
US84745806P | 2006-09-27 | 2006-09-27 | |
US60/847,458 | 2006-09-27 | ||
US92634907P | 2007-04-26 | 2007-04-26 | |
US60/926,349 | 2007-04-26 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2008027402A2 WO2008027402A2 (en) | 2008-03-06 |
WO2008027402A3 true WO2008027402A3 (en) | 2008-10-30 |
Family
ID=39136548
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2007/018951 WO2008027402A2 (en) | 2006-08-29 | 2007-08-28 | Brachytherapy devices and related methods and computer program products |
Country Status (2)
Country | Link |
---|---|
US (2) | US7686756B2 (en) |
WO (1) | WO2008027402A2 (en) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2293842B1 (en) * | 2008-05-02 | 2020-08-12 | Civatech Oncology | Brachytherapy devices and related methods |
WO2011018792A1 (en) * | 2009-08-12 | 2011-02-17 | Soreq NRC | Brachytherapy radioactive seeds compositions and methods for producing them |
US10350431B2 (en) | 2011-04-28 | 2019-07-16 | Gt Medical Technologies, Inc. | Customizable radioactive carriers and loading system |
DE102011101339A1 (en) | 2011-05-12 | 2012-11-15 | Walter Assmann | Radiation source useful for brachytherapy for cancer treatment comprises carrier material and activatable substance transferable by neutron activation in radioactive isotopes and embedded in carrier material without using chemical compound |
US9492683B2 (en) | 2013-03-15 | 2016-11-15 | Gammatile Llc | Dosimetrically customizable brachytherapy carriers and methods thereof in the treatment of tumors |
US9821174B1 (en) | 2015-02-06 | 2017-11-21 | Gammatile Llc | Radioactive implant planning system and placement guide system |
AU2016293866A1 (en) * | 2015-07-16 | 2017-12-14 | Sonavex, Inc. | Microcavity-containing polymeric medical devices for enhanced ultrasonic echogenicity |
JP7370860B2 (en) * | 2016-10-25 | 2023-10-30 | コーニンクレッカ フィリップス エヌ ヴェ | Radiation therapy system that accurately localizes 3D objects from magnetic resonance images |
US10888710B1 (en) | 2016-11-29 | 2021-01-12 | Gt Medical Technologies, Inc. | Transparent loading apparatus |
US10981018B2 (en) | 2019-02-14 | 2021-04-20 | Gt Medical Technologies, Inc. | Radioactive seed loading apparatus |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20030092957A1 (en) * | 1998-11-18 | 2003-05-15 | Scott Neal A. | Brachytherapy device and method of use |
US6659933B2 (en) * | 1999-12-07 | 2003-12-09 | Asano & Associates Corporation | Radiation source wire member for treating cancer and its delivery apparatus |
WO2004009253A1 (en) * | 2002-07-19 | 2004-01-29 | University Of North Carolina At Chapel Hill | Surface-localized release of an anti-biofouling agent via micropatterning |
US7223282B1 (en) * | 2001-09-27 | 2007-05-29 | Advanced Cardiovascular Systems, Inc. | Remote activation of an implantable device |
Family Cites Families (69)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2475155A (en) * | 1945-12-27 | 1949-07-05 | Baker & Co Inc | Process of producing a supported platinum metal catalyst |
US3351049A (en) | 1965-04-12 | 1967-11-07 | Hazleton Nuclear Science Corp | Therapeutic metal seed containing within a radioactive isotope disposed on a carrier and method of manufacture |
PH12898A (en) | 1973-05-23 | 1979-10-04 | Procter & Gamble | A composition for the treatment of calcific tumors |
US4323055A (en) | 1980-04-08 | 1982-04-06 | Minnesota Mining And Manufacturing Company | Radioactive iodine seed |
US4510924A (en) * | 1980-07-10 | 1985-04-16 | Yale-New Haven Hospital, Inc. | Brachytherapy devices and methods employing americium-241 |
US4754745A (en) | 1984-11-21 | 1988-07-05 | Horowitz Bruce S | Conformable sheet material for use in brachytherapy |
US4702228A (en) | 1985-01-24 | 1987-10-27 | Theragenics Corporation | X-ray-emitting interstitial implants |
US4763642A (en) | 1986-04-07 | 1988-08-16 | Horowitz Bruce S | Intracavitational brachytherapy |
US4891165A (en) | 1988-07-28 | 1990-01-02 | Best Industries, Inc. | Device and method for encapsulating radioactive materials |
US4994013A (en) | 1988-07-28 | 1991-02-19 | Best Industries, Inc. | Pellet for a radioactive seed |
US5134207A (en) | 1989-08-14 | 1992-07-28 | Virginia Tech Intellectual Properties, Inc. | Polyarylene ethers and polyarylene sulfides containing phosphine oxide group and modified by reaction with organoamine |
US5199939B1 (en) | 1990-02-23 | 1998-08-18 | Michael D Dake | Radioactive catheter |
CA2016492A1 (en) * | 1990-05-10 | 1991-11-10 | Farouk Tawfik Awadalla | Recovery of platinum group metals (pgm) from acidic solutions by reduction precipitation with sodium borohydride |
US5079333A (en) | 1990-07-13 | 1992-01-07 | Virginia Tech Intellectual Properties, Inc. | Novel mine-terminated poly(arylene ether phosphine oxide) oligomer |
US5342283A (en) | 1990-08-13 | 1994-08-30 | Good Roger R | Endocurietherapy |
US6099457A (en) * | 1990-08-13 | 2000-08-08 | Endotech, Inc. | Endocurietherapy |
US5354257A (en) | 1991-01-29 | 1994-10-11 | Med Institute, Inc. | Minimally invasive medical device for providing a radiation treatment |
US5407528A (en) | 1992-07-28 | 1995-04-18 | The Center For Innovative Technology | Oxygen plasma resistant polymeric film and fiber forming macromolecules containing the phosphine oxide moiety |
US5405309A (en) | 1993-04-28 | 1995-04-11 | Theragenics Corporation | X-ray emitting interstitial implants |
US5683345A (en) | 1994-10-27 | 1997-11-04 | Novoste Corporation | Method and apparatus for treating a desired area in the vascular system of a patient |
US5899882A (en) | 1994-10-27 | 1999-05-04 | Novoste Corporation | Catheter apparatus for radiation treatment of a desired area in the vascular system of a patient |
US5840008A (en) | 1995-11-13 | 1998-11-24 | Localmed, Inc. | Radiation emitting sleeve catheter and methods |
US5713828A (en) | 1995-11-27 | 1998-02-03 | International Brachytherapy S.A | Hollow-tube brachytherapy device |
US6589502B1 (en) | 1995-11-27 | 2003-07-08 | International Brachytherapy S.A. | Radioisotope dispersed in a matrix for brachytherapy |
US5840009A (en) | 1995-12-05 | 1998-11-24 | Isostent, Inc. | Radioisotope stent with increased radiation field strength at the ends of the stent |
US5916143A (en) | 1996-04-30 | 1999-06-29 | Apple; Marc G. | Brachytherapy catheter system |
US5871436A (en) | 1996-07-19 | 1999-02-16 | Advanced Cardiovascular Systems, Inc. | Radiation therapy method and device |
US5782740A (en) | 1996-08-29 | 1998-07-21 | Advanced Cardiovascular Systems, Inc. | Radiation dose delivery catheter with reinforcing mandrel |
US5691442A (en) | 1996-09-17 | 1997-11-25 | The United States Of America As Represented By The Secretary Of The Air Force | Transparent poly(arylene ether) compositions |
US5869141A (en) | 1996-11-04 | 1999-02-09 | The Boeing Company | Surface pretreatment for sol coating of metals |
US5871437A (en) | 1996-12-10 | 1999-02-16 | Inflow Dynamics, Inc. | Radioactive stent for treating blood vessels to prevent restenosis |
US5894133A (en) | 1996-12-18 | 1999-04-13 | Implant Science Corporation | Sputter cathode for application of radioactive material |
US5873811A (en) | 1997-01-10 | 1999-02-23 | Sci-Med Life Systems | Composition containing a radioactive component for treatment of vessel wall |
US5993374A (en) | 1997-06-17 | 1999-11-30 | Radiance Medical Systems, Inc. | Microcapsules for site-specific delivery |
US5851315A (en) * | 1997-07-16 | 1998-12-22 | Iso-Science Laboratories, Inc. | Process for producing radioisotope source |
KR100228188B1 (en) | 1997-12-24 | 1999-11-01 | 김성년 | A radioactive stent and process for preparation thereof |
WO1999039765A2 (en) | 1998-02-10 | 1999-08-12 | Implant Sciences Corporation | Soft x-ray emitting medical devices |
TW496741B (en) | 1998-03-12 | 2002-08-01 | Dept Of Health R O C | Radioactive particles and method for producing the same |
US6293899B1 (en) | 1998-03-24 | 2001-09-25 | Radiomed Corporation | Transmutable radiotherapy device |
US6143431A (en) * | 1998-05-04 | 2000-11-07 | Webster; Brian A. | Production of Palladium-103 |
US6086942A (en) | 1998-05-27 | 2000-07-11 | International Brachytherapy S.A. | Fluid-jet deposition of radioactive material for brachytherapy devices |
JP2002524108A (en) | 1998-07-28 | 2002-08-06 | インナーダイン, インコーポレイテッド | Absorbable brachytherapy and chemotherapy delivery devices and methods |
AU1064800A (en) | 1998-11-12 | 2000-06-05 | Nycomed Amersham Plc | Products and methods |
WO2000029501A1 (en) * | 1998-11-18 | 2000-05-25 | Emory University | Radioactive coating solutions, methods, and substrates |
EP1008995A1 (en) | 1998-12-12 | 2000-06-14 | Eurotope Entwicklungsgesellschaft für Isotopentechnologien mbH | Medical radioactive palladium-103 miniature radiation sources and methods of producing same |
US6358531B1 (en) | 1999-02-01 | 2002-03-19 | The Curators Of The University Of Missouri | Method for preparing porous shells or gels from glass particles |
AU2815400A (en) | 1999-02-25 | 2000-09-14 | Nycomed Amersham Plc | Medical tools and devices with improved ultrasound visibility |
US20030022383A1 (en) | 1999-04-06 | 2003-01-30 | Uab Research Foundation | Method for screening crystallization conditions in solution crystal growth |
US6679824B1 (en) | 1999-04-28 | 2004-01-20 | Medi-Physics, Inc. | Products and methods for brachytherapy |
SE523926C2 (en) | 1999-06-15 | 2004-06-01 | Hans Lundqvist | stent Events |
US6547816B1 (en) | 1999-07-12 | 2003-04-15 | Civatech Corporation | Formable integral source material for medical devices |
US6264599B1 (en) * | 1999-08-10 | 2001-07-24 | Syntheon, Llc | Radioactive therapeutic seeds having fixation structure |
DE19953637A1 (en) | 1999-11-09 | 2001-05-23 | Karlsruhe Forschzent | Neutron-activated radioactive material comprising rare earth compound, preferably thulium oxide, in matrix, e.g. of polymer, useful in medicine, e.g. for producing restenosis-preventing stents |
US6575888B2 (en) * | 2000-01-25 | 2003-06-10 | Biosurface Engineering Technologies, Inc. | Bioabsorbable brachytherapy device |
US6572525B1 (en) * | 2000-05-26 | 2003-06-03 | Lisa Yoshizumi | Needle having an aperture for detecting seeds or spacers loaded therein and colored seeds or spacers |
US20020055851A1 (en) | 2000-07-28 | 2002-05-09 | Donald L. Jacobs | Military installment loan and educational services system |
US6949064B2 (en) * | 2000-10-20 | 2005-09-27 | Bard Brachytherapy, Inc. | Brachytherapy seed deployment system |
EP1545705A4 (en) | 2000-11-16 | 2010-04-28 | Microspherix Llc | Flexible and/or elastic brachytherapy seed or strand |
US6638205B1 (en) * | 2000-11-17 | 2003-10-28 | Mds (Canada) Inc. | Radioactive medical device for radiation therapy |
AU2002323130A1 (en) * | 2001-08-13 | 2003-03-03 | Schering Aktiengesellschaft | Radioactive implantable devices and their production methods |
US7074291B2 (en) * | 2001-11-02 | 2006-07-11 | Worldwide Medical Technologies, L.L.C. | Delivery system and method for interstitial radiation therapy using strands constructed with extruded strand housings |
US7322928B2 (en) * | 2003-03-17 | 2008-01-29 | Medi-Physics, Inc. | Products and methods for brachytherapy |
AU2003903387A0 (en) | 2003-07-02 | 2003-07-17 | Sirtex Medical Limited | Combination therapy for treatment of neoplasia |
WO2005115543A1 (en) * | 2004-05-20 | 2005-12-08 | Wisconsin Alumni Research Foundation | Directionally emitting radioactive sources for brachytherapy |
WO2006110197A2 (en) * | 2005-03-03 | 2006-10-19 | Icon Medical Corp. | Polymer biodegradable medical device |
US7736293B2 (en) * | 2005-07-22 | 2010-06-15 | Biocompatibles Uk Limited | Implants for use in brachytherapy and other radiation therapy that resist migration and rotation |
WO2007021776A2 (en) * | 2005-08-09 | 2007-02-22 | Board Of Regents, The University Of Texas System | Methods and devices for breast reconstruction |
BRPI0616514A2 (en) | 2005-08-11 | 2011-06-21 | Navotek Medical Ltd | medical treatment system and method using position sensor based radioactivity |
WO2011015958A2 (en) * | 2009-08-06 | 2011-02-10 | Koninklijke Philips Electronics N.V. | Oncology therapies employing radioactive seeds |
-
2007
- 2007-08-28 US US11/846,075 patent/US7686756B2/en active Active
- 2007-08-28 WO PCT/US2007/018951 patent/WO2008027402A2/en active Application Filing
-
2010
- 2010-03-22 US US12/728,584 patent/US9358377B2/en active Active
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20030092957A1 (en) * | 1998-11-18 | 2003-05-15 | Scott Neal A. | Brachytherapy device and method of use |
US6659933B2 (en) * | 1999-12-07 | 2003-12-09 | Asano & Associates Corporation | Radiation source wire member for treating cancer and its delivery apparatus |
US7223282B1 (en) * | 2001-09-27 | 2007-05-29 | Advanced Cardiovascular Systems, Inc. | Remote activation of an implantable device |
WO2004009253A1 (en) * | 2002-07-19 | 2004-01-29 | University Of North Carolina At Chapel Hill | Surface-localized release of an anti-biofouling agent via micropatterning |
Also Published As
Publication number | Publication date |
---|---|
WO2008027402A2 (en) | 2008-03-06 |
US7686756B2 (en) | 2010-03-30 |
US20100233352A1 (en) | 2010-09-16 |
US9358377B2 (en) | 2016-06-07 |
US20080058580A1 (en) | 2008-03-06 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
WO2008027402A3 (en) | Brachytherapy devices and related methods and computer program products | |
EP2077457A4 (en) | Radiation dosimeter and radiation dose computing program | |
IL175387A0 (en) | Implantable radiotherapy/brachytherapy radiation detecting apparatus and methods | |
Yan et al. | Measurement of neutron dose equivalent to proton therapy patients outside of the proton radiation field | |
EP2223720A4 (en) | Radiation therapy planning device and radiation therapy planning method | |
GB2427479B (en) | Particle Radiation Therapy Equipment and method for performing particle radiation therapy | |
EP2252368A4 (en) | Radiation therapy plan dose perturbation system and method | |
EP1909904A4 (en) | Methods and apparatus for the planning and delivery of radiation treatments | |
HK1129332A1 (en) | Apparatus for irradiation of fluid with electromagnetic radiation and method for the same | |
EP1820171A4 (en) | Inverse ratio of gamma-ray and neutron emissions in the detection of radiation shielding in containers | |
EP2231276A4 (en) | Methods and devices for orthovoltage ocular radiotherapy and treatment planning | |
SE0202106D0 (en) | Radiation therapy device | |
EP2175795A4 (en) | Implantable devices and methods for external beam radiation treatments | |
Williamson | The sievert integral revisited: evaluation and extension to125I, 169Yb, and 192Ir brachytherapy sources | |
WO2008150511A3 (en) | Method and system for the calculation of dose responses for radiotherapy treatment planning | |
FR2870005B1 (en) | DOSE DETECTOR AND DOSIMETER | |
Wang et al. | Spot scanning proton therapy minimizes neutron dose in the setting of radiation therapy administered during pregnancy | |
Pozzi et al. | Dosimetry and radiobiology at the new RA-3 reactor boron neutron capture therapy (BNCT) facility: application to the treatment of experimental oral cancer | |
Najem et al. | The physical characteristics of the 15 MV Varian Clinac 2100C unflattened beam | |
Pashazadeh et al. | Calculation of beta radiation dose of a circular Y-90 skin patch: Analytical and simulation methods | |
Jahangiri et al. | The effect of field size and distance from the field center on neutron contamination in medical linear accelerator | |
Higueret et al. | Real-time detection of fast and thermal neutrons in radiotherapy with CMOS sensors | |
Gueulette et al. | Fast neutrons: Inexpensive and reliable tool to investigate high-LET particle radiobiology | |
Wang et al. | Induced radioactivity in stereotactic body radiation therapy with a flattening‐filter‐free 10 MV beam model | |
Rowshanfarzad et al. | Improvement of Varian a-Si EPID dosimetry measurements using a lead-shielded support-arm |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
121 | Ep: the epo has been informed by wipo that ep was designated in this application |
Ref document number: 07811578 Country of ref document: EP Kind code of ref document: A2 |
|
NENP | Non-entry into the national phase |
Ref country code: DE |
|
NENP | Non-entry into the national phase |
Ref country code: RU |
|
122 | Ep: pct application non-entry in european phase |
Ref document number: 07811578 Country of ref document: EP Kind code of ref document: A2 |