WO2008057266A3 - Dry granulation binders, products, and use thereof - Google Patents
Dry granulation binders, products, and use thereof Download PDFInfo
- Publication number
- WO2008057266A3 WO2008057266A3 PCT/US2007/022684 US2007022684W WO2008057266A3 WO 2008057266 A3 WO2008057266 A3 WO 2008057266A3 US 2007022684 W US2007022684 W US 2007022684W WO 2008057266 A3 WO2008057266 A3 WO 2008057266A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- mpa
- microcrystalline cellulose
- cellulose containing
- products
- dry granulate
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
- A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
Abstract
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2009534666A JP2010507676A (en) | 2006-10-27 | 2007-10-26 | Dry granulating binder, product and use thereof |
EP07852967A EP2076249A2 (en) | 2006-10-27 | 2007-10-26 | Dry granulation binders, products, and use thereof |
Applications Claiming Priority (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US85510606P | 2006-10-27 | 2006-10-27 | |
US85506606P | 2006-10-27 | 2006-10-27 | |
US60/855,106 | 2006-10-27 | ||
US60/855,066 | 2006-10-27 | ||
US92816607P | 2007-05-08 | 2007-05-08 | |
US60/928,166 | 2007-05-08 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2008057266A2 WO2008057266A2 (en) | 2008-05-15 |
WO2008057266A3 true WO2008057266A3 (en) | 2008-11-13 |
Family
ID=39317157
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2007/022684 WO2008057266A2 (en) | 2006-10-27 | 2007-10-26 | Dry granulation binders, products, and use thereof |
PCT/US2007/022685 WO2008057267A2 (en) | 2006-10-27 | 2007-10-26 | Co-processed microcrystalline cellulose and sugar alcohol as an excipient for tablet formulations |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2007/022685 WO2008057267A2 (en) | 2006-10-27 | 2007-10-26 | Co-processed microcrystalline cellulose and sugar alcohol as an excipient for tablet formulations |
Country Status (7)
Country | Link |
---|---|
US (3) | US8932629B2 (en) |
EP (2) | EP2076249A2 (en) |
JP (2) | JP5410290B2 (en) |
AT (1) | ATE493972T1 (en) |
DE (1) | DE602007011792D1 (en) |
TW (2) | TW200826976A (en) |
WO (2) | WO2008057266A2 (en) |
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US8632819B2 (en) * | 2009-12-22 | 2014-01-21 | Fmc Corporation | Microcrystalline cellulose and calcium carbonate compositions useful as recompactible pharmaceutical excipients |
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AT509515B1 (en) | 2010-06-23 | 2012-10-15 | Chemiefaser Lenzing Ag | USE OF CELLULOSE IN TABLETS |
CA2821799C (en) | 2010-12-16 | 2020-01-14 | Merck Patent Gmbh | Dry granulated cell culture media |
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WO2013052118A1 (en) | 2011-10-05 | 2013-04-11 | Fmc Corporation | Stabilizer composition of co-attrited microcrystalline cellulose and carboxymethylcellulose, method for making, and uses |
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BR112014013792B8 (en) | 2011-12-09 | 2020-11-10 | Dupont Nutrition Usa Inc | co-rubbed stabilizing composition comprising high-substitution, low-viscosity carboxymethyl cellulose, food, industrial composition, and method for making the stabilizing composition |
WO2014087422A1 (en) * | 2012-12-03 | 2014-06-12 | Zim Laboratories Limited | Chewable milk compositions and fortified powder formulations thereof |
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JP6104038B2 (en) * | 2013-05-02 | 2017-03-29 | 旭化成株式会社 | Composite composition of crystalline cellulose |
CN105616418A (en) * | 2014-11-07 | 2016-06-01 | 江苏豪森药业集团有限公司 | Pharmaceutical preparation containing cyclin inhibitor, and preparation method thereof |
US11059756B1 (en) | 2015-09-29 | 2021-07-13 | Intrepid Potash, Inc. | Pelletized fertilizer and methods of preparing pelletized fertilizer |
RU2019110362A (en) * | 2016-10-24 | 2020-11-24 | Пауль ГЕРТАЙС | METHODS AND DEVICES FOR CONTROL OF THE DRY GRANULATION PROCESS |
CN107063906B (en) * | 2016-12-16 | 2020-01-07 | 中国农业科学院农产品加工研究所 | Quantitative characterization method for moisture absorption and caking degree of powder |
CN107960663A (en) * | 2017-11-24 | 2018-04-27 | 南通励成生物工程有限公司 | Carbonic acid calcium-nutrition intensifying agent and preparation method |
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KR20200043618A (en) * | 2018-10-18 | 2020-04-28 | 주식회사유한양행 | Pharmaceutical composition for oral administration comprising an aminopyrimidine derivative or its salt |
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2007
- 2007-10-26 WO PCT/US2007/022684 patent/WO2008057266A2/en active Application Filing
- 2007-10-26 US US11/925,235 patent/US8932629B2/en active Active
- 2007-10-26 DE DE602007011792T patent/DE602007011792D1/en active Active
- 2007-10-26 EP EP07852967A patent/EP2076249A2/en not_active Withdrawn
- 2007-10-26 JP JP2009534667A patent/JP5410290B2/en active Active
- 2007-10-26 WO PCT/US2007/022685 patent/WO2008057267A2/en active Application Filing
- 2007-10-26 EP EP07852968A patent/EP2076250B1/en active Active
- 2007-10-26 JP JP2009534666A patent/JP2010507676A/en active Pending
- 2007-10-26 AT AT07852968T patent/ATE493972T1/en not_active IP Right Cessation
- 2007-10-26 US US11/925,375 patent/US7998505B2/en not_active Expired - Fee Related
- 2007-10-29 TW TW096140653A patent/TW200826976A/en unknown
- 2007-10-29 TW TW096140652A patent/TW200824721A/en unknown
-
2011
- 2011-08-10 US US13/207,022 patent/US20110294904A1/en not_active Abandoned
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5789004A (en) * | 1995-12-15 | 1998-08-04 | Fmc Corporation | Coprocessed microcrystalline cellulose stabilizer compositions, foods containing the same and stabilization method |
WO2001019348A1 (en) * | 1999-09-17 | 2001-03-22 | Mylan Pharmaceuticals Inc. | Stabilization of enalapril maleate with maleic acid |
EP1226818A1 (en) * | 2001-01-26 | 2002-07-31 | Pfizer Products Inc. | Pharmaceutical dosage forms with enhanced cohesive and compressibility properties |
WO2005030177A2 (en) * | 2003-09-29 | 2005-04-07 | Cipla Limited | Pharmaceutical formulation with improved stability |
Non-Patent Citations (1)
Title |
---|
R.C. ROWE, P.J. SHESKEY, P.J. WELLER: "Handbook of pharmaceutical excipients, fourth edition", 2003, PHARMACEUTICAL PRESS, LONDON, XP002481910 * |
Also Published As
Publication number | Publication date |
---|---|
JP5410290B2 (en) | 2014-02-05 |
JP2010507676A (en) | 2010-03-11 |
WO2008057267A3 (en) | 2008-07-24 |
US20110294904A1 (en) | 2011-12-01 |
US7998505B2 (en) | 2011-08-16 |
WO2008057267A2 (en) | 2008-05-15 |
WO2008057266A2 (en) | 2008-05-15 |
JP2010507677A (en) | 2010-03-11 |
US20080213360A1 (en) | 2008-09-04 |
EP2076249A2 (en) | 2009-07-08 |
ATE493972T1 (en) | 2011-01-15 |
US20080131505A1 (en) | 2008-06-05 |
EP2076250B1 (en) | 2011-01-05 |
TW200824721A (en) | 2008-06-16 |
TW200826976A (en) | 2008-07-01 |
EP2076250A2 (en) | 2009-07-08 |
DE602007011792D1 (en) | 2011-02-17 |
US8932629B2 (en) | 2015-01-13 |
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