WO2008070356A3 - Block biodegradable copolymers for medical devices - Google Patents

Block biodegradable copolymers for medical devices Download PDF

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Publication number
WO2008070356A3
WO2008070356A3 PCT/US2007/082954 US2007082954W WO2008070356A3 WO 2008070356 A3 WO2008070356 A3 WO 2008070356A3 US 2007082954 W US2007082954 W US 2007082954W WO 2008070356 A3 WO2008070356 A3 WO 2008070356A3
Authority
WO
WIPO (PCT)
Prior art keywords
medical devices
biodegradable copolymers
controlled release
block copolymers
block biodegradable
Prior art date
Application number
PCT/US2007/082954
Other languages
French (fr)
Other versions
WO2008070356A2 (en
Inventor
Ya Guo
Peiwen Cheng
Original Assignee
Medtronic Vascular Inc
Ya Guo
Peiwen Cheng
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medtronic Vascular Inc, Ya Guo, Peiwen Cheng filed Critical Medtronic Vascular Inc
Priority to EP07871282A priority Critical patent/EP2104522A2/en
Publication of WO2008070356A2 publication Critical patent/WO2008070356A2/en
Publication of WO2008070356A3 publication Critical patent/WO2008070356A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/04—Macromolecular materials
    • A61L31/06—Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/08—Materials for coatings
    • A61L31/10—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/16—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/416—Anti-neoplastic or anti-proliferative or anti-restenosis or anti-angiogenic agents, e.g. paclitaxel, sirolimus

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Surgery (AREA)
  • Vascular Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Transplantation (AREA)
  • Materials For Medical Uses (AREA)
  • Polymers & Plastics (AREA)

Abstract

Disclosed herein are implantable medical devices comprising controlled release biodegradable block copolymers or coated with controlled release block copolymers and at least one drug releasable from the block copolymer. The controlled release block copolymers comprise least two blocks selected from the group consisting of polyesters, polyethers, and polyurethanes.
PCT/US2007/082954 2006-11-06 2007-10-30 Block biodegradable copolymers for medical devices WO2008070356A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP07871282A EP2104522A2 (en) 2006-11-06 2007-10-30 Block biodegradable copolymers for medical devices

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11/556,865 US7691402B2 (en) 2006-11-06 2006-11-06 Block biodegradable copolymers for medical devices
US11/556,865 2006-11-06

Publications (2)

Publication Number Publication Date
WO2008070356A2 WO2008070356A2 (en) 2008-06-12
WO2008070356A3 true WO2008070356A3 (en) 2009-08-06

Family

ID=39359970

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2007/082954 WO2008070356A2 (en) 2006-11-06 2007-10-30 Block biodegradable copolymers for medical devices

Country Status (3)

Country Link
US (2) US7691402B2 (en)
EP (1) EP2104522A2 (en)
WO (1) WO2008070356A2 (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090004243A1 (en) 2007-06-29 2009-01-01 Pacetti Stephen D Biodegradable triblock copolymers for implantable devices
US8852620B2 (en) * 2007-07-20 2014-10-07 Medtronic Vascular, Inc. Medical devices comprising polymeric drug delivery systems with drug solubility gradients
US7956100B2 (en) * 2007-09-28 2011-06-07 Abbott Cardiovascular Systems Inc. Implantable medical devices fabricated from block copolymers
US8642062B2 (en) 2007-10-31 2014-02-04 Abbott Cardiovascular Systems Inc. Implantable device having a slow dissolving polymer
US8501290B2 (en) 2008-01-15 2013-08-06 Abbott Cardiovascular Systems Inc. Implantable medical devices fabricated from polyurethanes with biodegradable hard and soft blocks and blends thereof
US20090285873A1 (en) * 2008-04-18 2009-11-19 Abbott Cardiovascular Systems Inc. Implantable medical devices and coatings therefor comprising block copolymers of poly(ethylene glycol) and a poly(lactide-glycolide)
US8916188B2 (en) * 2008-04-18 2014-12-23 Abbott Cardiovascular Systems Inc. Block copolymer comprising at least one polyester block and a poly (ethylene glycol) block
US20110111170A1 (en) * 2008-05-30 2011-05-12 Canon Kabushiki Kaisha Block copolymer film and method of producing the same
KR101236198B1 (en) * 2011-02-08 2013-02-22 아주대학교산학협력단 Polyethyleneglycol/polyester block copolymers with side functional group as biocompatible thermo-sensitive materials and manufacturing method thereof
US8952126B2 (en) * 2013-07-10 2015-02-10 Xerox Corporation Purification of functionalized triblock copolymers via methanol trituration

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003090807A1 (en) * 2002-04-24 2003-11-06 Poly-Med, Inc. Multifaceted endovascular stent coating for preventing restenosis
US20050112170A1 (en) * 2003-11-20 2005-05-26 Hossainy Syed F. Coatings for implantable devices comprising polymers of lactic acid and methods for fabricating the same
US20050147647A1 (en) * 2003-12-24 2005-07-07 Thierry Glauser Coatings for implantable medical devices comprising hydrophilic substances and methods for fabricating the same

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4057537A (en) * 1975-01-28 1977-11-08 Gulf Oil Corporation Copolymers of L-(-)-lactide and epsilon caprolactone
CA2066876C (en) * 1991-06-06 1999-12-14 Matthew B. Hoyt Acid-dye resistant polyamide products and process for preparation
US5994341A (en) * 1993-07-19 1999-11-30 Angiogenesis Technologies, Inc. Anti-angiogenic Compositions and methods for the treatment of arthritis
US5362718A (en) * 1994-04-18 1994-11-08 American Home Products Corporation Rapamycin hydroxyesters
JP2001514278A (en) * 1997-08-25 2001-09-11 ユニオン・カーバイド・ケミカルズ・アンド・プラスティックス・テクノロジー・コーポレイション Condensation copolymers with suppressed crystallinity
US6015815A (en) * 1997-09-26 2000-01-18 Abbott Laboratories Tetrazole-containing rapamycin analogs with shortened half-lives
US6153252A (en) * 1998-06-30 2000-11-28 Ethicon, Inc. Process for coating stents
US6338739B1 (en) 1999-12-22 2002-01-15 Ethicon, Inc. Biodegradable stent
US6545097B2 (en) * 2000-12-12 2003-04-08 Scimed Life Systems, Inc. Drug delivery compositions and medical devices containing block copolymer
KR100453130B1 (en) * 2001-11-21 2004-10-15 한국과학기술연구원 Sequentially Ordered Biodegradable Lactide(Glycolide or Lactide/Glycolide)/ε-Caprolactone Multi-Block Copolymer and Process for the Preparation Thereof

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003090807A1 (en) * 2002-04-24 2003-11-06 Poly-Med, Inc. Multifaceted endovascular stent coating for preventing restenosis
US20050112170A1 (en) * 2003-11-20 2005-05-26 Hossainy Syed F. Coatings for implantable devices comprising polymers of lactic acid and methods for fabricating the same
US20050147647A1 (en) * 2003-12-24 2005-07-07 Thierry Glauser Coatings for implantable medical devices comprising hydrophilic substances and methods for fabricating the same

Also Published As

Publication number Publication date
US20080107704A1 (en) 2008-05-08
WO2008070356A2 (en) 2008-06-12
US8968763B2 (en) 2015-03-03
US20100158981A1 (en) 2010-06-24
EP2104522A2 (en) 2009-09-30
US7691402B2 (en) 2010-04-06

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