WO2008083767A1 - Gewebte aortensinusprothese mit bulbus - Google Patents
Gewebte aortensinusprothese mit bulbus Download PDFInfo
- Publication number
- WO2008083767A1 WO2008083767A1 PCT/EP2007/009080 EP2007009080W WO2008083767A1 WO 2008083767 A1 WO2008083767 A1 WO 2008083767A1 EP 2007009080 W EP2007009080 W EP 2007009080W WO 2008083767 A1 WO2008083767 A1 WO 2008083767A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- prosthesis
- aortic sinus
- section
- woven
- threads
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/04—Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
- A61F2/06—Blood vessels
-
- D—TEXTILES; PAPER
- D03—WEAVING
- D03D—WOVEN FABRICS; METHODS OF WEAVING; LOOMS
- D03D13/00—Woven fabrics characterised by the special disposition of the warp or weft threads, e.g. with curved weft threads, with discontinuous warp threads, with diagonal warp or weft
- D03D13/004—Woven fabrics characterised by the special disposition of the warp or weft threads, e.g. with curved weft threads, with discontinuous warp threads, with diagonal warp or weft with weave pattern being non-standard or providing special effects
-
- D—TEXTILES; PAPER
- D03—WEAVING
- D03D—WOVEN FABRICS; METHODS OF WEAVING; LOOMS
- D03D13/00—Woven fabrics characterised by the special disposition of the warp or weft threads, e.g. with curved weft threads, with discontinuous warp threads, with diagonal warp or weft
- D03D13/008—Woven fabrics characterised by the special disposition of the warp or weft threads, e.g. with curved weft threads, with discontinuous warp threads, with diagonal warp or weft characterised by weave density or surface weight
-
- D—TEXTILES; PAPER
- D03—WEAVING
- D03D—WOVEN FABRICS; METHODS OF WEAVING; LOOMS
- D03D15/00—Woven fabrics characterised by the material, structure or properties of the fibres, filaments, yarns, threads or other warp or weft elements used
- D03D15/40—Woven fabrics characterised by the material, structure or properties of the fibres, filaments, yarns, threads or other warp or weft elements used characterised by the structure of the yarns or threads
- D03D15/49—Woven fabrics characterised by the material, structure or properties of the fibres, filaments, yarns, threads or other warp or weft elements used characterised by the structure of the yarns or threads textured; curled; crimped
-
- D—TEXTILES; PAPER
- D03—WEAVING
- D03D—WOVEN FABRICS; METHODS OF WEAVING; LOOMS
- D03D3/00—Woven fabrics characterised by their shape
- D03D3/02—Tubular fabrics
-
- D—TEXTILES; PAPER
- D03—WEAVING
- D03D—WOVEN FABRICS; METHODS OF WEAVING; LOOMS
- D03D3/00—Woven fabrics characterised by their shape
- D03D3/06—Fabrics of varying width
-
- D—TEXTILES; PAPER
- D06—TREATMENT OF TEXTILES OR THE LIKE; LAUNDERING; FLEXIBLE MATERIALS NOT OTHERWISE PROVIDED FOR
- D06M—TREATMENT, NOT PROVIDED FOR ELSEWHERE IN CLASS D06, OF FIBRES, THREADS, YARNS, FABRICS, FEATHERS OR FIBROUS GOODS MADE FROM SUCH MATERIALS
- D06M10/00—Physical treatment of fibres, threads, yarns, fabrics, or fibrous goods made from such materials, e.g. ultrasonic, corona discharge, irradiation, electric currents, or magnetic fields; Physical treatment combined with treatment with chemical compounds or elements
- D06M10/008—Treatment with radioactive elements or with neutrons, alpha, beta or gamma rays
-
- D—TEXTILES; PAPER
- D06—TREATMENT OF TEXTILES OR THE LIKE; LAUNDERING; FLEXIBLE MATERIALS NOT OTHERWISE PROVIDED FOR
- D06M—TREATMENT, NOT PROVIDED FOR ELSEWHERE IN CLASS D06, OF FIBRES, THREADS, YARNS, FABRICS, FEATHERS OR FIBROUS GOODS MADE FROM SUCH MATERIALS
- D06M15/00—Treating fibres, threads, yarns, fabrics, or fibrous goods made from such materials, with macromolecular compounds; Such treatment combined with mechanical treatment
- D06M15/01—Treating fibres, threads, yarns, fabrics, or fibrous goods made from such materials, with macromolecular compounds; Such treatment combined with mechanical treatment with natural macromolecular compounds or derivatives thereof
- D06M15/15—Proteins or derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2250/0014—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof having different values of a given property or geometrical feature, e.g. mechanical property or material property, at different locations within the same prosthesis
- A61F2250/0015—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof having different values of a given property or geometrical feature, e.g. mechanical property or material property, at different locations within the same prosthesis differing in density or specific weight
- A61F2250/0017—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof having different values of a given property or geometrical feature, e.g. mechanical property or material property, at different locations within the same prosthesis differing in density or specific weight differing in yarn density
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2250/0014—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof having different values of a given property or geometrical feature, e.g. mechanical property or material property, at different locations within the same prosthesis
- A61F2250/0039—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof having different values of a given property or geometrical feature, e.g. mechanical property or material property, at different locations within the same prosthesis differing in diameter
-
- D—TEXTILES; PAPER
- D10—INDEXING SCHEME ASSOCIATED WITH SUBLASSES OF SECTION D, RELATING TO TEXTILES
- D10B—INDEXING SCHEME ASSOCIATED WITH SUBLASSES OF SECTION D, RELATING TO TEXTILES
- D10B2509/00—Medical; Hygiene
- D10B2509/06—Vascular grafts; stents
Definitions
- the present invention relates to a woven aortic sinus prosthesis.
- vascular prostheses are usually implanted after removal of aneurysmal parts of the ascending aorta and, in particular, after removal of the aortic sinus (natural sinus) to obtain the aortic valves and parts of the arterial wall.
- vascular prostheses produced first were straight and homogeneous tube prostheses.
- a disadvantage of such vascular prostheses is that they lack additional structures, which could in particular replace the function of surgically removed aortic sinus. Thus, they reflect the actual anatomical conditions of the aorta ascendens only insufficient.
- US Pat. No. 6,544,285 B1 and WO 01/52776 A1 disclose tube-shaped vascular prostheses for the replacement of the aorta ascendens, which have artificial sinuses in the vicinity of the heart to replace the aortic sinus.
- the artificial sinuses are sewn to the prosthesis.
- Sutured sutures produce arched bulges at the proximal end of the vascular prosthesis.
- EP 0 955 019 A2 relates to tubular vascular prostheses which have a general circumferential bulge in the region of the aortic bulb. Also, this prosthesis configuration does not correspond to the actual anatomy of the ascending aorta.
- a significantly improved tubular vascular prosthesis in this respect is described in WO 2004/021925 A2, according to which the tube in the region of the ascending aorta has at least two artificial sinuses, which have a greater extent to the outside than the tube itself.
- US Pat. No. 5,139,515 described an aortic prosthesis with sinusoidal bulges, but without disclosing details of the formation of the bulges.
- WO 2005/099624 A1 describes a woven aortic sinus prosthesis with a substantially spherical bulb section. To manufacture a complicated weaving technique is required.
- a woven aortic sinus prosthesis with a first, heart-distant, substantially cylindrical portion, which optionally merges into an aortic arch, a second, compared to the first section in diameter-expanded, a bulge (bulge) forming section, the connects the first section, and optionally a third, substantially cylindrical, near-the-heart section, which adjoins the buil- bus connects.
- the aortic sinus prosthesis according to the invention is woven throughout and has over its axial length a constant number of warp threads, wherein the warp threads in the region of the bulbar section have a greater distance from one another than in cylindrical regions of the prosthesis.
- the invention provides an aortic sinus prosthesis which is particularly suitable for the replacement of the ascending aorta. Due to the bulbus-shaped second section, the prosthesis particularly corresponds to the anatomical conditions of the natural aorta, in particular with regard to the natural sinuses.
- the globe can fill with blood during systole, which is carried on during diastole because of the preferably elastic properties of the prosthesis.
- the bulbous section has a maximum diameter which is 1 to 45%, preferably 10 to 40%, in particular 15 to 35%, greater than the diameter of cylindrical sections of the aortic sinus prosthesis according to the invention.
- the bulbus diameter may be up to 50% larger than the diameter of the cylindrical section.
- the diameter of the aortic sinus prosthesis in the cylindrical regions is 24 to 40 mm, as a rule 28 to 32 mm, and in the bulbous region a maximum of 30 to 50 mm, generally a maximum of 32 to 48 mm, in particular a maximum of 34 to 38 mm.
- the first, heart-distant cylindrical section preferably has a length of 20 to 150 mm, in particular 50 to 100 mm and in special cases up to 200 mm.
- the bulb preferably has an axial length of 20 to 50 mm, in particular 25 to 30 mm, in special cases up to 60 mm.
- a third, substantially cylindrical, heart-proximal prosthesis section has an axial length of 5 to 30 mm, in particular 10 to 20 mm.
- the vascular prosthesis according to the invention is in addition to the replacement of the ascending aorta also for remodeling the aortic root (annulus).
- the Bulbusabites has in the axial direction preferably three longitudinal subsections, of which a first, herzferner subsection has a continuous, in particular continuous increase in distance of the warp threads, a second, middle subsection substantially constant distances of the warp threads and a third, near the heart subsection a steady taper of the distances the warp threads are up to the diameter of the cylindrical portion of the prosthesis.
- the bulbus section has two longitudinal subsections in the axial direction, with a second, heart-like subsection directly adjoining a first, heart-distant subsection having a continuous, in particular continuous increase in spacing of the warp threads, with a continuous tapering of the spacing of the warp threads. According to the invention, provision is made in particular for the three or two bulb subsections to have different lengths in the axial direction.
- the first Bulbusunter- section is at least as long as a third subsection.
- the first bulbus subsection is longer than a third section.
- the diameter increase of the first section is correspondingly more gradual. The same applies to conicity of the first section in this case.
- the warp threads in the Bulbusabites are uniformly expanded seen in the circumferential direction, so that A uniform bulge extending over the whole circumference results.
- the warp threads in the bus section can have different distances from one another in cross section.
- the bulbous section may comprise three single bulbs formed by three circumferential regions with increased pitches of warp threads.
- the warp threads between the Einzelbulbi can either have unchanged warp pitches compared to the cylindrical prosthesis sections or enlarged distances, but which are smaller than in the bellies of Einzelbulbi.
- the distance enlargement can be designed such that the bulb section or the individual bulbs are subdivided into individual subsections or have a uniform balloon-shaped transition.
- the threads may be single filaments or multifilaments.
- the threads are preferably yarns.
- the threads are expediently formed from a biocompatible material.
- polyester especially polyethylene terephthalate may be mentioned.
- the aortic sinus prosthesis according to the invention may have a water permeability in the range from 0 to 500 ml / cm 2 min, in particular in the range from 200 to 250 ml / cm 2 min. These water permeability values were measured according to Wesolowski's method of determination at 120 mmHg. In this way, the aortic sinus prosthesis is blood-tight after a short time and the risk of oozing bleeding is low.
- the tissue of the aortic sinus prosthesis according to the invention is in particular in a thickness of 0.1 to 0.35 mm, preferably from 0.15 to 0.25 mm formed. The thickness is determined according to DIN 863.
- the fabric is formed with threads of yarn thickness 10 to 200 dtex.
- the yarn may for example have a twist of 50 to 500 revolutions / m.
- the threads of the woven aortic sinus prosthesis may furthermore have in particular 10 to 200 filaments, in particular 20 to 150 filaments, preferably about 80 filaments per thread.
- the fabric may be formed with a repeat of 8 x 8.
- the thread density of the warp threads in the cylindrical prosthesis section is 30 to 120 threads per cm of prosthesis circumference, in particular 40 to 80 threads per cm of the circumference of the prosthesis.
- the thread density of the weft threads in the cylindrical prosthesis section is preferably between 10 and 70 threads per cm of prosthesis length, in particular with 20 to 50 threads per cm of prosthesis length.
- the first off-center portion and the third near-heart portion have different inner diameters associated with a correspondingly different Kettfadenabstand.
- the near-hearted third section preferably has a larger inner diameter.
- the inner diameters of vascular prostheses are usually even in the ascending row of the prosthesis size by 2 mm larger.
- the diameter difference between the third and the first section is also 2 mm.
- the near-the heart third section may also have a smaller inner diameter than the first section away from the heart, so that the conditions are reversed. It is also possible to form the first and / or third section slightly conical.
- the aortic sinus prosthesis according to the invention is designed substantially in plain weave.
- the aortic sinus prosthesis according to the invention may in particular have a framework with plain weave.
- the warp threads are preferably only smooth threads.
- the warp threads are only textured threads.
- the fabric may be formed from a combination of smooth and textured threads.
- the overall ratio of smooth to textured yarns may be 1: 1 to 6: 1, especially 3: 1.
- the tissue of the aortic sinus prosthesis according to the invention contains at least 50% of smooth, that is to say non-textured, threads.
- smooth and textured threads may be used, in particular in an alternating sequence, the ratio of smooth to textured threads being in the ratio between 2: 1 and 1: 2, in particular approx. 1: 1.
- the weft threads may be smooth or textured.
- the weft threads are smooth threads.
- smooth and textured threads may be used as weft threads, in particular in alternating sequence, wherein the ratio of smooth to textured threads in the ratio between 5: 1 and 1: 5.
- the weft threads can be closer to one another in the area of the globe than in the cylindrical prosthesis area. This means that the weft threads are preferably compacted in this area.
- shrinkage yarns can be used. These preferably have an absolute shrinkability of at least 20%, preferably a shrinkage which is at least 30%, preferably at least 40%, higher than any shrinkability of the weft threads of the eyeball, the shrinkability being based on non-shrinkable threads (0%) ,
- the difference in diameter between the substantially cylindrical portions and the bulbous portion may be formed at least in part by the differential shrinkage of the weft threads. Also, diameter differences between the substantially cylindrical sections, within these sections and within the bulb can be obtained in this way.
- the aortic sinus prosthesis according to the invention preferably has a pleating at least in the first, cylindrical prosthesis section. Also in the third cylindrical prosthesis section pleating is possible.
- the pleating is preferably a transverse pleating.
- the aortic sinus prosthesis according to the invention is extensible in the circumferential direction in the region of the bulbous portion.
- the aortic sinus prosthesis preferably has a longitudinal pleating in the bulbous region.
- Pleating folds of the longitudinal pleating may be thermally (fixed), in particular to the outside.
- floats, in particular warp threads running in the warp direction can be introduced.
- Such a floating thread is preferably present in addition to and in particular parallel beside a warp thread in the plain weave. The additional floating thread runs where it is in plain weave, preferably together with the parallel warp thread and meets again after flooding with the warp thread.
- the floats can be flat in the tissue surface and in particular do not form loops.
- the floating threads can be textured.
- a floated textured thread is adjacent to two smooth strands of the fabric in the fabric weave running in the same direction.
- tissue of the aortic sinus prosthesis according to the invention can be formed only from smooth threads with a floatation of textured threads.
- the fabric of alternately smooth and textured threads may be formed with a float of textured threads, in particular, only every second textured thread has a float.
- the floats preferably run only in the warp direction. In another embodiment, the floats may be in both the warp and weft directions.
- the float threads can be introduced in particular in the warp direction and in the weft direction in different numbers.
- the floats extend over more than 2 threads, in particular over 3 to 10 threads, preferably over 4 to 6 threads.
- the float can be 4 to 6 over 1, preferably 4 over 2 or 5 over 1.
- a floatation above 5 under 1 above 1 below 1 may be introduced.
- an odd number is preferred because otherwise the float thread is no longer parallel to an adjacent fabric thread of a plain weave.
- the ratio of float threads to warp threads can be between 1:20 and 1: 1, in particular between 1:10 and 1: 2, preferably 1: 3.
- floats can be present in a proportion of about 5 to 50%, in particular 9 to 33%, preferably 25%, with respect to the warp threads in the fabric.
- floats of adjacent floats can be offset in the warp direction, preferably at least a portion of the floats overlaps.
- the distance between the float threads in the weft direction may be the same in each case.
- at least three threads of the base fabric can be in between.
- the floats can float only on one surface.
- the binding of the fabric on the outside of the aortic sinus prosthesis on floats which consist in particular of textuherten threads. This allows fibroblasts from the surrounding tissue to grow into the outside of the aortic sinus prosthesis and form the collagen for external encapsulation of the prosthesis.
- the prosthesis inside is preferably free of floats.
- the inside of the aortic sinus prosthesis according to the invention has a smoother surface than the outside. This can in particular favor the ingrowth of a neointima.
- sothel cells form a new thin and smooth neointima starting from vascular stumps.
- a smooth inner surface is created.
- an outside is produced which has a voluminous structure compared to the inside.
- a porosity gradient is obtained towards the inner surface of the aortic sinus prosthesis according to the invention, whereby an improved ingrowth of blood vessels is achieved with simultaneous favorable formation of the neointima.
- the aortic sinus prosthesis according to the invention is sealingly impregnated.
- resorbable materials are preferably used.
- Suitable impregnating materials are, for example, gelatin and other suitable natural or synthetic materials.
- the impregnation materials are crosslinked after coating the aortic sinus prosthesis.
- the aortic sinus prosthesis is preferably free of connective sutures.
- the bulb has a plurality of, in particular three, longitudinally extending in the wall of the globe, reinforcements.
- the reinforcements may in particular be denture material, plastics or metals.
- the reinforcements may be gathered prosthetic material.
- the reinforcements may be formed by additional prosthesis material which is sewn onto the aortic sinus prosthesis, for example.
- the reinforcements are preferred web-shaped or strip-shaped.
- the aortic sinus prosthesis according to the invention can be equipped with medically active substances.
- active substances in particular antibiotics, antiseptics, coagulation factors, growth factors and the like come into consideration.
- the aortic sinus prosthesis may be shrunk in particular by thermal fixation.
- textured threads can be opened by the shrinkage.
- the aortic sinus prosthesis according to the invention is furthermore preferably present in sterilized and in particular ready-made form.
- FIG. 1 shows a side view of an embodiment of the aortic sinus prosthesis according to the invention
- FIG. 2 a top view of the rightmost warp thread of an alternative to the embodiment according to FIG. 1
- FIG. 5 shows a cross section of an unevenly enlarged bulb section
- Figure 6 a side view of another embodiment
- Figure 7 a cross section of another embodiment.
- a woven aortic sinus prosthesis 1 has a portion 2 remote from the heart, which is cylindrical apart from a transverse pleating 3.
- the off-center portion 2 can merge seamlessly at its upper end 4 or by means of a transverse seam in an aortic arch, not shown in the drawing.
- the non-cardiac section 2 of the aortic sinus prosthesis passes axially and seamlessly into a bulbar section 6.
- the bulbus section 6 can be expanded evenly (FIGS. 1 and 4) or unevenly (FIG. 5) viewed in the circumferential direction.
- the Bulbusabites 6 has a Querplisstechnik 3.
- the Bulbusabiteses 6 connects axially and seamlessly a substantially cylindrical near-the heart section 8, which in turn is cylindrical apart from the Querplisstechnik 3.
- the transverse pleating 3 thus extends over the entire length of the aortic sinus prosthesis 1.
- the warp threads 9 in Bulbusabites 6 a gradually increasing and again decreasing greater distance from each other than in the cylindrical sections 2 and 8. This results in a balloon-like eyeball 6.
- the weft threads 10 in Bulbusabrough 6 closer together than in the cylindrical areas of the aortic sinus prosthesis 1.
- a globe 6 has three peripheral sections 11 in which the pitches of the warp threads are greatly widened, and three peripheral sections 12 therebetween in which the pitches of the warp threads are widened less, thereby forming three individual sheets 11 or at least hinted.
- the bulb section 6 can accommodate a natural or an artificial heart valve.
- the lower cylindrical portion 8 may also be shortened or cut off as needed, depending on how much of the natural aortic neck (annulus) stops at implantation.
- the three sections are substantially the same as in the embodiment of Figure 1. Therefore, corresponding reference numerals are used.
- the difference to the embodiment of Figure 1 is that the near-heart section 8 'has a larger inner diameter than the first non-cardiac section 2.
- the diameter difference is preferably 2 mm.
- the first off-center portion has an inner diameter of, for example, 28 mm
- the inner diameter is the near-the heart third section 8 '30 mm.
- the number of warp threads remains unchanged. Only the warp spacing is greater in the heart near third section than in the first section away from the heart.
- the diameter difference is also approx. 2 mm, in each case for larger or smaller anterior sinus prostheses with larger or smaller inner diameters.
- a tubular prosthesis with a diameter of 28 mm is woven in plain weave.
- the prosthesis produced in this way has an axial length of about 30 mm, a Bulbus (Aussackung) with a diameter of about 32 mm. Above and below the bulb, the prosthesis produced has a diameter of about 28 mm.
- the prosthesis can be woven as an arbitrarily long tube, in which the Bulbusabête repeat at predetermined intervals. By cutting between the Bulbusab mustarden the prosthesis blanks are obtained. For the production of the prosthesis, weft threads with different degrees of shrinkability can be used.
- weft threads used for the eyeball are not or only slightly shrinkable, can be used for the substantially cylindrical sections shrinking yarns, which have a shrinkability of at least 30%.
- shrink yarns are known and can have a shrinkage of up to 70%. By appropriate selection of such shrinking yarns can be gradual or abrupt
- Differences in diameter are formed or reinforced in the prosthesis.
- the shrinkage is generated in particular by a thermal treatment of the woven prosthesis.
- the prosthesis blanks are pleated after their preparation above the globe and optionally below the globe.
- the pleated areas are then added to approx. 10 cm and approx. 3 cm in length. right cut.
- three webs 13 (FIG. 7) are sewn into the unpleated bulb by tightening the prosthesis material in the longitudinal direction of the prosthesis as reinforcements equidistant from one another with a width of approximately 3 mm.
- the prosthesis is coated with gelatin.
- the gelatin is crosslinked.
- the prosthesis is subjected to ⁇ sterilization.
- the prosthesis can be provided with a longitudinal plication in the area of the globe.
- three longitudinal pleats 14 are provided.
Abstract
Description
Claims
Priority Applications (8)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US12/520,284 US8728152B2 (en) | 2006-12-22 | 2007-10-19 | Woven aortic sinus prosthesis having a bulb |
JP2009541789A JP5216778B2 (ja) | 2006-12-22 | 2007-10-19 | 球状部を有する織布大動脈洞プロテーゼ |
CN2007800475032A CN101610738B (zh) | 2006-12-22 | 2007-10-19 | 具有球状部分的织造主动脉窦假体 |
DE502007003072T DE502007003072D1 (de) | 2006-12-22 | 2007-12-20 | Gewebte Aortensinusprothese mit Bulbus |
DE202007018508U DE202007018508U1 (de) | 2006-12-22 | 2007-12-20 | Gewebte Aortensinusprothese mit Bulbus |
AT07024710T ATE460136T1 (de) | 2006-12-22 | 2007-12-20 | Gewebte aortensinusprothese mit bulbus |
EP07024710.1A EP1935375B2 (de) | 2006-12-22 | 2007-12-20 | Gewebte Aortensinusprothese mit Bulbus |
ES07024710.1T ES2342431T5 (es) | 2006-12-22 | 2007-12-20 | Prótesis tejida del seno aórtico con bulbos |
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE102006062360.6 | 2006-12-22 | ||
DE102006062360A DE102006062360A1 (de) | 2006-12-22 | 2006-12-22 | Gewebte Aortensinusprothese mit Bulbus |
DE102007013428A DE102007013428A1 (de) | 2006-12-22 | 2007-03-13 | Gewebte Aortensinusprothese mit Bulbus |
DE102007013428.4 | 2007-03-13 |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2008083767A1 true WO2008083767A1 (de) | 2008-07-17 |
Family
ID=38961255
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/EP2007/009080 WO2008083767A1 (de) | 2006-12-22 | 2007-10-19 | Gewebte aortensinusprothese mit bulbus |
Country Status (8)
Country | Link |
---|---|
US (1) | US8728152B2 (de) |
EP (1) | EP1935375B2 (de) |
JP (1) | JP5216778B2 (de) |
CN (1) | CN101610738B (de) |
AT (1) | ATE460136T1 (de) |
DE (4) | DE102006062360A1 (de) |
ES (1) | ES2342431T5 (de) |
WO (1) | WO2008083767A1 (de) |
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WO2010127040A1 (en) * | 2009-04-28 | 2010-11-04 | Endologix, Inc. | Apparatus and method of placement of a graft or graft system |
WO2012088475A1 (en) * | 2010-12-23 | 2012-06-28 | Maquet Cardiovascular Llc | Woven prosthesis and method for manufacturing the same |
US20120253452A1 (en) * | 2009-12-28 | 2012-10-04 | Cook Medical Technologies Llc | Thoracic graft having yarn modifications |
US8388679B2 (en) | 2007-01-19 | 2013-03-05 | Maquet Cardiovascular Llc | Single continuous piece prosthetic tubular aortic conduit and method for manufacturing the same |
WO2017186706A1 (en) * | 2016-04-27 | 2017-11-02 | Hector Daniel Barone | Prosthesis for treating abdominal aortic aneurysm and method |
US10245166B2 (en) | 2008-02-22 | 2019-04-02 | Endologix, Inc. | Apparatus and method of placement of a graft or graft system |
EP3552577A1 (de) * | 2018-04-13 | 2019-10-16 | Heart Biotech Nano Limited | Synthetische wurzel |
US11129737B2 (en) | 2015-06-30 | 2021-09-28 | Endologix Llc | Locking assembly for coupling guidewire to delivery system |
US11213412B2 (en) | 2012-08-10 | 2022-01-04 | Abiomed, Inc. | Graft anchor devices, systems and methods |
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DE102021134525A1 (de) | 2021-12-23 | 2023-06-29 | Rheinisch-Westfälische Technische Hochschule (RWTH) Aachen, Körperschaft des öffentlichen Rechts | Implantierbare Klappenprothesen mit gewebten Klappensegeln |
CN114959989B (zh) * | 2022-06-29 | 2023-11-28 | 山东黄河三角洲纺织科技研究院有限公司 | 一种人造血管及其立体编织方法 |
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US8388679B2 (en) | 2007-01-19 | 2013-03-05 | Maquet Cardiovascular Llc | Single continuous piece prosthetic tubular aortic conduit and method for manufacturing the same |
US10245166B2 (en) | 2008-02-22 | 2019-04-02 | Endologix, Inc. | Apparatus and method of placement of a graft or graft system |
JP2012525227A (ja) * | 2009-04-28 | 2012-10-22 | エンドロジックス、インク | 移植片あるいは移植片システムを配置する装置および方法 |
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US8945202B2 (en) | 2009-04-28 | 2015-02-03 | Endologix, Inc. | Fenestrated prosthesis |
US10603196B2 (en) | 2009-04-28 | 2020-03-31 | Endologix, Inc. | Fenestrated prosthesis |
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US10292809B2 (en) * | 2009-12-28 | 2019-05-21 | Cook Medical Technologies Llc | Thoracic graft having yarn modifications |
US11406518B2 (en) | 2010-11-02 | 2022-08-09 | Endologix Llc | Apparatus and method of placement of a graft or graft system |
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US10010401B2 (en) | 2010-12-23 | 2018-07-03 | Maquet Cardiovascular Llc | Woven prosthesis and method for manufacturing the same |
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US10682221B2 (en) | 2010-12-23 | 2020-06-16 | Maquet Cardiovascular Llc | Woven prosthesis and method for manufacturing the same |
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US11517417B2 (en) | 2010-12-23 | 2022-12-06 | Maquet Cardiovascular Llc | Woven prosthesis and method for manufacturing the same |
US11213412B2 (en) | 2012-08-10 | 2022-01-04 | Abiomed, Inc. | Graft anchor devices, systems and methods |
US11129737B2 (en) | 2015-06-30 | 2021-09-28 | Endologix Llc | Locking assembly for coupling guidewire to delivery system |
WO2017186706A1 (en) * | 2016-04-27 | 2017-11-02 | Hector Daniel Barone | Prosthesis for treating abdominal aortic aneurysm and method |
US10849732B2 (en) | 2016-04-27 | 2020-12-01 | Hector Daniel Barone | Prosthesis for treating abdominal aortic aneurysm and method |
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US11291541B2 (en) | 2018-04-13 | 2022-04-05 | Heart Biotech Nano Limited | Expandable aortic or pulmonary root |
Also Published As
Publication number | Publication date |
---|---|
DE102006062360A1 (de) | 2008-06-26 |
US8728152B2 (en) | 2014-05-20 |
CN101610738A (zh) | 2009-12-23 |
JP5216778B2 (ja) | 2013-06-19 |
US20100094390A1 (en) | 2010-04-15 |
EP1935375A1 (de) | 2008-06-25 |
ES2342431T3 (es) | 2010-07-06 |
ATE460136T1 (de) | 2010-03-15 |
DE502007003072D1 (de) | 2010-04-22 |
ES2342431T5 (es) | 2016-03-02 |
CN101610738B (zh) | 2013-09-18 |
DE202007018508U1 (de) | 2008-09-11 |
EP1935375B2 (de) | 2015-12-23 |
JP2010512867A (ja) | 2010-04-30 |
DE102007013428A1 (de) | 2008-09-18 |
EP1935375B1 (de) | 2010-03-10 |
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