WO2008089270A3 - Flow chamber device for neutralization of cancer cells - Google Patents
Flow chamber device for neutralization of cancer cells Download PDFInfo
- Publication number
- WO2008089270A3 WO2008089270A3 PCT/US2008/051211 US2008051211W WO2008089270A3 WO 2008089270 A3 WO2008089270 A3 WO 2008089270A3 US 2008051211 W US2008051211 W US 2008051211W WO 2008089270 A3 WO2008089270 A3 WO 2008089270A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- neutralization
- cancer cells
- flow chamber
- chamber device
- cancer cell
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3679—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits by absorption
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/0081—Purging biological preparations of unwanted cells
- C12N5/0093—Purging against cancer cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0693—Tumour cells; Cancer cells
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- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Vascular Medicine (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Hematology (AREA)
- Animal Behavior & Ethology (AREA)
- Cell Biology (AREA)
- Oncology (AREA)
- Veterinary Medicine (AREA)
- Microbiology (AREA)
- Public Health (AREA)
- Cardiology (AREA)
- Anesthesiology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Abstract
The present invention relates to methods and apparatuses for neutralizing cancer cells. In particular, the invention relates to separating of cancer cell type from a mixture of different cell types based on the differential rolling property of cancer cell on a substrate coated with a first molecules that exhibits adhesive property with the particular cell type and neutralizing the cancer cell by a second molecule that is also coated on the substrate. This technology is adaptable for use in vivo, in vitro, or ex vivo tumor neutralization.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US88037907P | 2007-01-16 | 2007-01-16 | |
US60/880,379 | 2007-01-16 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2008089270A2 WO2008089270A2 (en) | 2008-07-24 |
WO2008089270A3 true WO2008089270A3 (en) | 2011-07-21 |
Family
ID=39636687
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2008/051211 WO2008089270A2 (en) | 2007-01-16 | 2008-01-16 | Flow chamber device for neutralization of cancer cells |
Country Status (1)
Country | Link |
---|---|
WO (1) | WO2008089270A2 (en) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2148696A4 (en) * | 2007-04-18 | 2010-12-08 | Massachusetts Inst Technology | Surfaces, methods and devices employing cell rolling |
CA2701034A1 (en) | 2007-09-27 | 2009-04-02 | Massachusetts Institute Of Technology | Cell rolling separation |
CN115254208A (en) * | 2014-03-07 | 2022-11-01 | 伊利诺伊大学评议会 | Biomimetic microfluidic device for capturing circulating tumor cells |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6365362B1 (en) * | 1998-02-12 | 2002-04-02 | Immunivest Corporation | Methods and reagents for the rapid and efficient isolation of circulating cancer cells |
US6433147B1 (en) * | 1997-01-28 | 2002-08-13 | Human Genome Sciences, Inc. | Death domain containing receptor-4 |
US20040191246A1 (en) * | 2003-02-26 | 2004-09-30 | Connelly Patrick R. | Process for in vivo treatment of specific biological targets in bodily fluid |
WO2006078994A2 (en) * | 2005-01-21 | 2006-07-27 | University Of Rochester | Continuous flow chamber device for separation, concentration, and/or purification of cells |
-
2008
- 2008-01-16 WO PCT/US2008/051211 patent/WO2008089270A2/en active Application Filing
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6433147B1 (en) * | 1997-01-28 | 2002-08-13 | Human Genome Sciences, Inc. | Death domain containing receptor-4 |
US6365362B1 (en) * | 1998-02-12 | 2002-04-02 | Immunivest Corporation | Methods and reagents for the rapid and efficient isolation of circulating cancer cells |
US20040191246A1 (en) * | 2003-02-26 | 2004-09-30 | Connelly Patrick R. | Process for in vivo treatment of specific biological targets in bodily fluid |
WO2006078994A2 (en) * | 2005-01-21 | 2006-07-27 | University Of Rochester | Continuous flow chamber device for separation, concentration, and/or purification of cells |
Also Published As
Publication number | Publication date |
---|---|
WO2008089270A2 (en) | 2008-07-24 |
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