WO2008094984A3 - Automatic injection and retraction devices for use with pre-filled syringe cartridges - Google Patents

Automatic injection and retraction devices for use with pre-filled syringe cartridges Download PDF

Info

Publication number
WO2008094984A3
WO2008094984A3 PCT/US2008/052427 US2008052427W WO2008094984A3 WO 2008094984 A3 WO2008094984 A3 WO 2008094984A3 US 2008052427 W US2008052427 W US 2008052427W WO 2008094984 A3 WO2008094984 A3 WO 2008094984A3
Authority
WO
WIPO (PCT)
Prior art keywords
retraction
injection
filled syringe
assembly
needle
Prior art date
Application number
PCT/US2008/052427
Other languages
French (fr)
Other versions
WO2008094984A2 (en
Inventor
Richard D Gillespie
Doug Owen Crow
Original Assignee
West Pharm Serv Inc
Richard D Gillespie
Doug Owen Crow
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by West Pharm Serv Inc, Richard D Gillespie, Doug Owen Crow filed Critical West Pharm Serv Inc
Publication of WO2008094984A2 publication Critical patent/WO2008094984A2/en
Publication of WO2008094984A3 publication Critical patent/WO2008094984A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M5/2033—Spring-loaded one-shot injectors with or without automatic needle insertion
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M2005/206—With automatic needle insertion
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M2005/2073—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically preventing premature release, e.g. by making use of a safety lock
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M2005/2086—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically having piston damping means, e.g. axially or rotationally acting retarders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • A61M2005/2418—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic comprising means for damping shocks on ampoule
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/3202—Devices for protection of the needle before use, e.g. caps
    • A61M5/3204—Needle cap remover, i.e. devices to dislodge protection cover from needle or needle hub, e.g. deshielding devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/46—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for controlling depth of insertion

Abstract

An automatic injection and retraction device having a longitudinal axis is provided that includes an injection assembly, a retraction assembly, and a pre- filled syringe cartridge. The injection assembly has an activation-prevention feature moveable between an on position and an off position. The retraction assembly has a needle guard that is removable in a direction along the longitudinal axis upon application of a removal force. The pre-filled syringe cartridge has a hypodermic needle with a needle sheath thereon. The retraction and injection assemblies are secured to one another so that the pre-filled syringe cartridge is in the retraction assembly with the needle sheath secured to the needle guard. The retraction and injection assemblies are configured so that, upon application of a twisting torque to the injection and retraction assemblies, the activation-prevention feature moves from the on position to the off position simultaneous with applying the removal force to the needle guard.
PCT/US2008/052427 2007-01-31 2008-01-30 Automatic injection and retraction devices for use with pre-filled syringe cartridges WO2008094984A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11/669,452 2007-01-31
US11/669,452 US7988675B2 (en) 2005-12-08 2007-01-31 Automatic injection and retraction devices for use with pre-filled syringe cartridges

Publications (2)

Publication Number Publication Date
WO2008094984A2 WO2008094984A2 (en) 2008-08-07
WO2008094984A3 true WO2008094984A3 (en) 2008-11-06

Family

ID=38140380

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2008/052427 WO2008094984A2 (en) 2007-01-31 2008-01-30 Automatic injection and retraction devices for use with pre-filled syringe cartridges

Country Status (2)

Country Link
US (1) US7988675B2 (en)
WO (1) WO2008094984A2 (en)

Families Citing this family (133)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1476210B1 (en) 2002-02-11 2008-09-24 Antares Pharma, Inc. Intradermal injector
US9486581B2 (en) * 2002-09-11 2016-11-08 Becton, Dickinson And Company Injector device with force lock-out and injection rate limiting mechanisms
JP4960252B2 (en) 2004-11-22 2012-06-27 インテリジェクト，インコーポレイテッド Device, system and method for drug delivery
US7648482B2 (en) 2004-11-22 2010-01-19 Intelliject, Inc. Devices, systems, and methods for medicament delivery
US7648483B2 (en) 2004-11-22 2010-01-19 Intelliject, Inc. Devices, systems and methods for medicament delivery
US7947017B2 (en) 2004-11-22 2011-05-24 Intelliject, Inc. Devices, systems and methods for medicament delivery
US11590286B2 (en) 2004-11-22 2023-02-28 Kaleo, Inc. Devices, systems and methods for medicament delivery
US10737028B2 (en) 2004-11-22 2020-08-11 Kaleo, Inc. Devices, systems and methods for medicament delivery
JP5216328B2 (en) 2005-01-24 2013-06-19 アンタレス ファーマ インコーポレイテッド Pre-filled needle assist syringe jet injector
ES2396745T3 (en) 2005-02-01 2013-02-25 Intelliject, Inc. Devices for medication administration
US8361026B2 (en) 2005-02-01 2013-01-29 Intelliject, Inc. Apparatus and methods for self-administration of vaccines and other medicaments
FR2899482A1 (en) * 2006-04-11 2007-10-12 Becton Dickinson France Soc Pa Automatic medicament/product injection device for patient, has safety shield coupled to housing, and provided in active state at end of needle insertion step before which product/medicament injection step is not started
US8251947B2 (en) 2006-05-03 2012-08-28 Antares Pharma, Inc. Two-stage reconstituting injector
WO2007131025A1 (en) 2006-05-03 2007-11-15 Antares Pharma, Inc. Injector with adjustable dosing
JP5211167B2 (en) * 2007-09-25 2013-06-12 ベクトン・ディキンソン・フランス・エス．エー．エス． Automatic syringe
RU2552306C2 (en) * 2008-01-23 2015-06-10 Ново Нордикс А/С Injection device for fixed dose of liquid medicinal product
US8992484B2 (en) * 2008-01-23 2015-03-31 Novo Nordisk A/S Device for injecting apportioned doses of liquid drug
CN101998869B (en) 2008-02-11 2013-04-17 特克法马许可公司 Administering apparatus comprising a blockable actuation element
US9241596B2 (en) * 2008-02-19 2016-01-26 Medela Holding Ag Breastmilk handling apparatus
EP2268342B1 (en) 2008-03-10 2015-09-16 Antares Pharma, Inc. Injector safety device
GB0806814D0 (en) * 2008-04-15 2008-05-14 Medical House Plc The Improved autoinjector
MX2010012691A (en) 2008-05-20 2011-03-30 Avant Medical Corp Star Autoinjector system.
US8177749B2 (en) 2008-05-20 2012-05-15 Avant Medical Corp. Cassette for a hidden injection needle
US8052645B2 (en) 2008-07-23 2011-11-08 Avant Medical Corp. System and method for an injection using a syringe needle
CN102065938B (en) * 2008-06-20 2014-09-03 西部制药服务公司 Automatic injection mechanism with frontal buttress
US8048029B2 (en) * 2008-06-20 2011-11-01 West Pharmaceutical Services, Inc. Injector apparatus
ES2738539T3 (en) 2008-08-05 2020-01-23 Antares Pharma Inc Multi dose injector
US8788211B2 (en) 2008-10-31 2014-07-22 The Invention Science Fund I, Llc Method and system for comparing tissue ablation or abrasion data to data related to administration of a frozen particle composition
US8725420B2 (en) 2008-10-31 2014-05-13 The Invention Science Fund I, Llc Compositions and methods for surface abrasion with frozen particles
US8603494B2 (en) * 2008-10-31 2013-12-10 The Invention Science Fund I, Llc Compositions and methods for administering compartmentalized frozen particles
US20100111857A1 (en) 2008-10-31 2010-05-06 Boyden Edward S Compositions and methods for surface abrasion with frozen particles
US8485861B2 (en) * 2008-10-31 2013-07-16 The Invention Science Fund I, Llc Systems, devices, and methods for making or administering frozen particles
US8221480B2 (en) 2008-10-31 2012-07-17 The Invention Science Fund I, Llc Compositions and methods for biological remodeling with frozen particle compositions
US8731840B2 (en) * 2008-10-31 2014-05-20 The Invention Science Fund I, Llc Compositions and methods for therapeutic delivery with frozen particles
US9072799B2 (en) 2008-10-31 2015-07-07 The Invention Science Fund I, Llc Compositions and methods for surface abrasion with frozen particles
US9050070B2 (en) 2008-10-31 2015-06-09 The Invention Science Fund I, Llc Compositions and methods for surface abrasion with frozen particles
US9072688B2 (en) * 2008-10-31 2015-07-07 The Invention Science Fund I, Llc Compositions and methods for therapeutic delivery with frozen particles
US8798932B2 (en) 2008-10-31 2014-08-05 The Invention Science Fund I, Llc Frozen compositions and methods for piercing a substrate
US8603495B2 (en) 2008-10-31 2013-12-10 The Invention Science Fund I, Llc Compositions and methods for biological remodeling with frozen particle compositions
US8721583B2 (en) * 2008-10-31 2014-05-13 The Invention Science Fund I, Llc Compositions and methods for surface abrasion with frozen particles
US9060926B2 (en) 2008-10-31 2015-06-23 The Invention Science Fund I, Llc Compositions and methods for therapeutic delivery with frozen particles
US8731841B2 (en) 2008-10-31 2014-05-20 The Invention Science Fund I, Llc Compositions and methods for therapeutic delivery with frozen particles
US8545856B2 (en) 2008-10-31 2013-10-01 The Invention Science Fund I, Llc Compositions and methods for delivery of frozen particle adhesives
US9060931B2 (en) 2008-10-31 2015-06-23 The Invention Science Fund I, Llc Compositions and methods for delivery of frozen particle adhesives
US9050317B2 (en) 2008-10-31 2015-06-09 The Invention Science Fund I, Llc Compositions and methods for therapeutic delivery with frozen particles
US9060934B2 (en) 2008-10-31 2015-06-23 The Invention Science Fund I, Llc Compositions and methods for surface abrasion with frozen particles
US8762067B2 (en) 2008-10-31 2014-06-24 The Invention Science Fund I, Llc Methods and systems for ablation or abrasion with frozen particles and comparing tissue surface ablation or abrasion data to clinical outcome data
US8793075B2 (en) 2008-10-31 2014-07-29 The Invention Science Fund I, Llc Compositions and methods for therapeutic delivery with frozen particles
EP2362968B1 (en) * 2008-11-05 2016-01-27 West Pharmaceutical Services, Inc. Barrier isolator port assembly
ES2719496T3 (en) 2008-11-12 2019-07-10 Medimmune Llc Antibody formulation
GB0901801D0 (en) * 2009-02-05 2009-03-11 Medical House Plc The Improved autoinjector
WO2010108116A1 (en) 2009-03-20 2010-09-23 Antares Pharma, Inc. Hazardous agent injection system
EP2255842B2 (en) 2009-05-26 2023-05-24 SHL Medical AG Needle cover assembly
US9233213B2 (en) 2009-10-16 2016-01-12 Janssen Biotech, Inc. Palm activated drug delivery device
NZ714959A (en) 2009-10-16 2016-09-30 Janssen Biotech Inc Palm activated drug delivery device
US9795744B2 (en) * 2009-12-15 2017-10-24 Shl Group Ab Medicament delivery device
WO2011101379A1 (en) 2010-02-18 2011-08-25 Sanofi-Aventis Deutschland Gmbh Auto-injector
FI2575935T4 (en) 2010-06-07 2023-11-23 Amgen Inc Drug delivery device
WO2012022734A2 (en) 2010-08-16 2012-02-23 Medimmune Limited Anti-icam-1 antibodies and methods of use
EP2468337A1 (en) * 2010-12-21 2012-06-27 Sanofi-Aventis Deutschland GmbH Back-end device for an auto-injector and auto-injector
US8939943B2 (en) 2011-01-26 2015-01-27 Kaleo, Inc. Medicament delivery device for administration of opioid antagonists including formulations for naloxone
US9084849B2 (en) 2011-01-26 2015-07-21 Kaleo, Inc. Medicament delivery devices for administration of a medicament within a prefilled syringe
US8627816B2 (en) 2011-02-28 2014-01-14 Intelliject, Inc. Medicament delivery device for administration of opioid antagonists including formulations for naloxone
US10092706B2 (en) * 2011-04-20 2018-10-09 Amgen Inc. Autoinjector apparatus
US8672883B2 (en) 2011-07-11 2014-03-18 C. Garyen Denning Fluid delivery device and methods
CA2840943A1 (en) * 2011-07-14 2013-01-17 Sanofi-Aventis Deutschland Gmbh Drive mechanism of a drug delivery device
US9220660B2 (en) 2011-07-15 2015-12-29 Antares Pharma, Inc. Liquid-transfer adapter beveled spike
US8496619B2 (en) 2011-07-15 2013-07-30 Antares Pharma, Inc. Injection device with cammed ram assembly
EP2606925A1 (en) * 2011-12-21 2013-06-26 Sanofi-Aventis Deutschland GmbH Autoinjector
JP6165786B2 (en) 2012-03-06 2017-07-19 アンタレス・ファーマ・インコーポレーテッド Filling syringe with release force feature
AU2013231466B2 (en) 2012-03-14 2016-04-21 Shl Medical Ag Medicament delivery device
KR20150011346A (en) 2012-04-06 2015-01-30 안타레스 팔마, 인코퍼레이티드 Needle assisted jet injection administration of testosterone compositions
USD808010S1 (en) 2012-04-20 2018-01-16 Amgen Inc. Injection device
USD898908S1 (en) 2012-04-20 2020-10-13 Amgen Inc. Pharmaceutical product cassette for an injection device
US9181572B2 (en) 2012-04-20 2015-11-10 Abbvie, Inc. Methods to modulate lysine variant distribution
WO2013169800A1 (en) 2012-05-07 2013-11-14 Antares Pharma, Inc. Injection device with cammed ram assembly
WO2013176754A1 (en) 2012-05-24 2013-11-28 Abbvie Inc. Novel purification of antibodies using hydrophobic interaction chromatography
DK2911724T3 (en) 2012-10-25 2017-11-06 Novo Nordisk As Pre-filled disposable injection apparatus
EP3916004B1 (en) 2012-12-03 2024-03-27 Novobiotic Pharmaceuticals, LLC Novel depsipeptide and uses thereof
CA2900672C (en) 2013-02-11 2018-03-27 Antares Pharma, Inc. Needle assisted jet injection device having reduced trigger force
US8652100B1 (en) 2013-03-08 2014-02-18 Teva Pharmaceutical Industries, Ltd. Re-useable injector device for syringe
US8591463B1 (en) * 2013-03-08 2013-11-26 Teva Pharmaceutical Industries Ltd. Re-useable injector device for syringe
JP6030803B2 (en) 2013-03-11 2016-11-24 アンタレス・ファーマ・インコーポレーテッド Dose syringe with pinion system
WO2014165136A1 (en) 2013-03-12 2014-10-09 Antares Pharma, Inc. Constant volume prefilled syringes and kits thereof
CA2926301A1 (en) 2013-03-14 2014-10-02 Abbvie Inc. Low acidic species compositions and methods for producing and using the same
EP2970375A1 (en) 2013-03-14 2016-01-20 AbbVie Inc. Low acidic species compositions and methods for producing the same using displacement chromatography
US10092703B2 (en) 2013-03-15 2018-10-09 Amgen Inc. Drug cassette, autoinjector, and autoinjector system
EP3593839A1 (en) 2013-03-15 2020-01-15 Amgen Inc. Drug cassette
CA3207252A1 (en) * 2013-03-15 2014-09-25 Janssen Biotech, Inc. Palm activated drug delivery device
GB2515032A (en) 2013-06-11 2014-12-17 Cilag Gmbh Int Guide for an injection device
GB2515038A (en) 2013-06-11 2014-12-17 Cilag Gmbh Int Injection device
GB2515039B (en) 2013-06-11 2015-05-27 Cilag Gmbh Int Injection Device
GB2517896B (en) * 2013-06-11 2015-07-08 Cilag Gmbh Int Injection device
US9492474B2 (en) 2013-07-10 2016-11-15 Matrix Biology Institute Compositions of hyaluronan with high elasticity and uses thereof
WO2015050959A1 (en) 2013-10-01 2015-04-09 Yale University Anti-kit antibodies and methods of use thereof
USD745664S1 (en) 2013-11-25 2015-12-15 Teva Pharmaceutical Industries, Ltd. Injector device for a syringe
KR102143632B1 (en) * 2013-12-30 2020-08-11 삼성메디슨 주식회사 Photoacoustic probe and photoacoustic diagnostic apparatus
PL2745866T3 (en) 2014-01-30 2017-04-28 Tecpharma Licensing Ag Release safety device for an auto-injector
US10751470B2 (en) 2014-02-10 2020-08-25 E3D A.C.A.L Ltd Semi disposable auto injector
EP3145561A1 (en) 2014-05-20 2017-03-29 Cequr SA Medicine delivery device with restricted access filling port
US20170226552A1 (en) 2014-07-03 2017-08-10 Abbvie Inc. Methods for modulating protein glycosylation profiles of recombinant protein therapeutics using cobalt
US20160185848A1 (en) 2014-07-09 2016-06-30 Abbvie Inc. Methods for modulating the glycosylation profile of recombinant proteins using sugars
US9517307B2 (en) 2014-07-18 2016-12-13 Kaleo, Inc. Devices and methods for delivering opioid antagonists including formulations for naloxone
CA3009221A1 (en) 2014-12-23 2016-06-30 Automed Pty Ltd Delivery apparatus, system and associated methods
US9415176B1 (en) 2015-01-22 2016-08-16 West Pharmaceutical Services, Inc. Autoinjector having an end-of-dose visual indicator
WO2016144773A1 (en) 2015-03-06 2016-09-15 Abbvie Inc. Arabinosylated glycoproteins
IL295010A (en) 2015-03-10 2022-09-01 Regeneron Pharma Aseptic piercing system and method
WO2017004345A1 (en) 2015-06-30 2017-01-05 Kaleo, Inc. Auto-injectors for administration of a medicament within a prefilled syringe
EP3834865A3 (en) 2015-08-27 2021-12-29 E3D Agricultural Cooperative Association Ltd. Reusable automatic injection device
CN108135926A (en) 2015-09-24 2018-06-08 基质生物研究所 High resiliency hyaluronic acid compositions and its application method
TW201729859A (en) 2015-11-27 2017-09-01 賽諾菲阿凡提斯德意志有限公司 A cap for an injection device
CN108367125B (en) * 2015-12-08 2022-01-25 贝克顿迪金森法国公司 Cap for medical syringe
WO2017147003A1 (en) 2016-02-26 2017-08-31 Novobiotic Pharmaceuticals, Llc Novel macrocyclic antibiotics and uses thereof
US10265476B2 (en) * 2016-03-11 2019-04-23 Shl Medical Ag Two body syringe carrier assembly with dampener
USD819198S1 (en) 2016-04-28 2018-05-29 Amgen Inc. Autoinjector with removable cap
GB201607491D0 (en) * 2016-04-29 2016-06-15 Owen Mumford Ltd Injection devices
JP6895462B2 (en) * 2016-06-22 2021-06-30 アンタレス・ファーマ・インコーポレーテッド Needle shield remover
USD824023S1 (en) * 2016-08-30 2018-07-24 Owen Mumford Limited Injection device
JP7014797B2 (en) 2016-12-23 2022-02-01 カレオ，インコーポレイテッド Drug delivery devices and methods for delivering drugs to babies and children
EP3606941A1 (en) 2017-04-04 2020-02-12 Novobiotic Pharmaceuticals, LLC Novel depsipeptides and uses thereof
BR112019020705A2 (en) 2017-05-05 2020-05-12 Regeneron Pharmaceuticals, Inc. AUTOINJECTOR
US11583633B2 (en) 2018-04-03 2023-02-21 Amgen Inc. Systems and methods for delayed drug delivery
EP4009936A4 (en) 2019-08-09 2023-08-09 Kaleo, Inc. Devices and methods for delivery of substances within a prefilled syringe
USD1010811S1 (en) 2019-09-30 2024-01-09 Amgen Inc. Handheld drug delivery device
CN112124611B (en) * 2020-08-22 2023-11-28 西安科为实业发展有限责任公司 Shelling separation system and method for cylindrical jet type folding wing aircraft
USD974547S1 (en) 2020-11-05 2023-01-03 Amgen Inc. Handheld drug delivery device
USD962423S1 (en) 2020-11-05 2022-08-30 Amgen Inc. Handheld drug delivery device
USD973866S1 (en) 2020-11-05 2022-12-27 Amgen Inc. Handheld drug delivery device
USD985117S1 (en) 2021-03-10 2023-05-02 Amgen Inc. Handheld drug delivery device
USD985118S1 (en) 2021-03-10 2023-05-02 Amgen Inc. Handheld drug delivery device
USD985116S1 (en) 2021-03-10 2023-05-02 Amgen Inc. Handheld drug delivery device
USD985119S1 (en) 2021-03-30 2023-05-02 Amgen Inc. Handheld drug delivery device
USD1007676S1 (en) 2021-11-16 2023-12-12 Regeneron Pharmaceuticals, Inc. Wearable autoinjector

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6183445B1 (en) * 1995-03-17 2001-02-06 Radiometer Medical A/S Syringe with retractable needle guard
US20040111064A1 (en) * 2002-12-10 2004-06-10 Asbaghi Hooman A. Position guide for a needle guard
US20050049551A1 (en) * 2003-09-03 2005-03-03 Fritz Kirchhofer Administering device with multiple-chamber ampoule and mixing block
US20060178631A1 (en) * 2004-12-09 2006-08-10 Pharma-Pen Holdings, Inc. Automatic injection and retraction syringe

Family Cites Families (123)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2561233A (en) * 1949-03-19 1951-07-17 Abbott Lab Hypodermic syringe
US3306290A (en) * 1964-02-14 1967-02-28 Harold S Weltman Automatically retractable needle syringe
US3572336A (en) * 1968-04-30 1971-03-23 Daniel R Hershberg Syringe
BE756550A (en) * 1969-09-23 1971-03-01 Sherwood Medical Ind Inc REAR LOADING SYRINGE AND PROCEDURE FOR ITS FILLING
US3707968A (en) * 1970-10-07 1973-01-02 Sherwood Medical Ind Inc Arming cap for breech loaded syringe
US3708089A (en) * 1971-01-11 1973-01-02 North American Rockwell Gas generator for liquid sprayers
US3834387A (en) * 1972-08-10 1974-09-10 Sherwood Medical Ind Inc Breech loaded syringe with deformable piston
US3901402A (en) * 1973-03-14 1975-08-26 Becton Dickinson Co Stopper-piston
US4059109A (en) * 1976-07-27 1977-11-22 Tischlinger Edward A Mixing and dispensing disposable medicament injector
US4445895A (en) * 1981-07-16 1984-05-01 Sterling Drug Inc. Prepackaged, disposable hypodermic syringes
IT1206220B (en) * 1981-09-30 1989-04-14 Caselgrandi Ivo Palmieri Benia SYRINGE PARTICULARLY SUITABLE FOR NEEDLE BIOPSIES WITH A DEVICE THAT ALLOWS THE SUCTION PHASE, GENERATED BY THE RETROSE STROKE STROKE AUTOMATICALLY
USD287603S (en) * 1983-12-19 1987-01-06 Koh-I-Noor Rapidograph, Inc. Writing pen
USD286164S (en) * 1983-12-19 1986-10-14 Koh-I-Noor Rapidograph, Inc. Writing pen
US4581016A (en) * 1984-02-29 1986-04-08 Gettig Pharmaceutical Instrument Co. Dual cartridge wet/dry syringe
FR2573310B1 (en) * 1984-11-20 1988-12-30 Poutrait Morin BULB FOR HYPODERMIC SYRINGE, IN PARTICULAR SELF-INJECTING SYRINGE
US4689042A (en) * 1985-05-20 1987-08-25 Survival Technology, Inc. Automatic medicament ingredient mixing and injecting apparatus
US4861335A (en) * 1985-07-26 1989-08-29 Duoject Medical Systems Inc. Syringe
ES2017924B3 (en) 1985-10-11 1991-03-16 Duphar Int Res B V AUTOMATIC INJECTOR.
US4795444A (en) * 1986-05-02 1989-01-03 Sunstar Kabushiki Kaisha Syringe
DE3773048D1 (en) * 1986-05-15 1991-10-24 Duphar Int Res AUTOMATIC INJECTION SYRINGE.
GB8702069D0 (en) * 1987-01-30 1987-03-04 High Trees Agriculture Ltd Cleaning agricultural sprayers
US4886495A (en) * 1987-07-08 1989-12-12 Duoject Medical Systems Inc. Vial-based prefilled syringe system for one or two component medicaments
US4767413A (en) * 1987-04-20 1988-08-30 Habley Medical Technology Corporation Dental syringe having an automatically retractable needle
GB8723454D0 (en) * 1987-10-06 1987-11-11 Beecham Group Plc Device
USRE35986E (en) * 1988-08-23 1998-12-08 Meridian Medical Technologies, Inc. Multiple chamber automatic injector
US4969877A (en) * 1988-10-19 1990-11-13 The Pascall Medical Corporation Syringe
ES2009709A6 (en) * 1989-01-24 1989-10-01 Villar Pascual Jose Antonio Single-use safety syringe
US5169385A (en) * 1989-01-26 1992-12-08 Turnbull Christopher J Safety I. V. drug introducer set
US5085642A (en) * 1989-07-17 1992-02-04 Survival Technology, Inc. Conveniently carried frequent use autoinjector
US5085641A (en) * 1989-07-17 1992-02-04 Survival Technology, Inc. Conveniently carried frequent use auto-injector with improved cap structure
US5102393A (en) * 1989-07-17 1992-04-07 Survival Technology, Inc. Autoinjector converted from intramuscular to subcutaneous mode of injection
US4998922A (en) * 1990-02-23 1991-03-12 Kuracina Thomas C Safety syringe cap minimizing needle-stick probability
US5092843A (en) * 1990-04-12 1992-03-03 Survival Technology, Inc. Dispersion multichamber auto-injector
GB9100819D0 (en) * 1991-01-15 1991-02-27 Medimech Int Ltd Subcutaneous injector
US5120310A (en) * 1991-04-03 1992-06-09 Shaw Thomas J Nonreusable syringe
US5267961A (en) * 1991-04-03 1993-12-07 Shaw Thomas J Nonreusable syringe with safety indicator
US5188613A (en) * 1991-04-03 1993-02-23 Shaw Thomas J Nonreusable syringe with safety indicator
GB9111600D0 (en) * 1991-05-30 1991-07-24 Owen Mumford Ltd Improvements relating to injection devices
USD339606S (en) * 1991-11-08 1993-09-21 Rotring-Werke Riepe, KG Fountain pen
GB9200219D0 (en) * 1992-01-07 1992-02-26 Medimech Int Ltd Automatic injectors
US5176657A (en) * 1992-01-15 1993-01-05 Shields Jack W Shot gun syringe with cartridge and scabbards
US5324273A (en) * 1992-09-30 1994-06-28 Centrix, Inc. Disposable barrel dental impression material syringe
US5411487A (en) * 1992-12-07 1995-05-02 Castagna; John F. Hypodermic syringe with automatic needle cover
US5373684A (en) * 1992-12-14 1994-12-20 Mallinckrodt Medical, Inc. Process and apparatus used in producing prefilled, sterile delivery devices
US5383865A (en) * 1993-03-15 1995-01-24 Eli Lilly And Company Medication dispensing device
DE69427226T2 (en) * 1993-03-24 2001-08-30 Owen Mumford Ltd DEVICE FOR INJECTION
GB9310163D0 (en) * 1993-05-18 1993-06-30 Owen Mumford Ltd Improvements relating to injection devices
US5695472A (en) * 1993-05-27 1997-12-09 Washington Biotech Corporation Modular automatic or manual emergency medicine injection system
US5358489A (en) * 1993-05-27 1994-10-25 Washington Biotech Corporation Reloadable automatic or manual emergency injection system
US5540664A (en) * 1993-05-27 1996-07-30 Washington Biotech Corporation Reloadable automatic or manual emergency injection system
US5364363A (en) * 1993-07-08 1994-11-15 Survival Technology, Inc. Rectal administrator
US5425715A (en) * 1993-08-05 1995-06-20 Survival Technology, Inc. Reloadable injector
US5385551A (en) * 1993-09-22 1995-01-31 Shaw; Thomas J. Nonreusable medical device with front retraction
US5620421A (en) * 1993-12-09 1997-04-15 Schmitz; William L. Syringe injector system
US5423758A (en) * 1993-12-16 1995-06-13 Shaw; Thomas J. Retractable fluid collection device
FR2715071B1 (en) * 1994-01-17 1996-03-01 Aguettant Lab Automatic drug injector.
US5413564A (en) * 1994-03-02 1995-05-09 Silver; Jules Predetermined dosage hypodermic syringe system
US5389076A (en) * 1994-04-05 1995-02-14 Shaw; Thomas J. Single use medical device with retraction mechanism
US5411489A (en) * 1994-05-06 1995-05-02 Sterling Winthrop Inc. Pre-filled syringe and pre-filled cartridge having actuating cylinder/plunger rod combination for reducing syringing force
GB9412301D0 (en) * 1994-06-17 1994-08-10 Safe T Ltd Hollow-needle drugs etc applicators
US5466223A (en) * 1994-06-20 1995-11-14 Becton, Dickinson And Company Needle assembly having single-handedly activatable needle barrier
US5545145A (en) * 1994-08-16 1996-08-13 Becton Dickinson And Company Pen needle despenser
US5637092A (en) * 1995-01-30 1997-06-10 Shaw; Thomas J. Syringe plunger locking assembly
US5685846A (en) * 1995-02-27 1997-11-11 Schott Parenta Systems, Inc. Dual chamber internal by-pass syringe assembly
AU696439B2 (en) 1995-03-07 1998-09-10 Eli Lilly And Company Recyclable medication dispensing device
FR2733155B1 (en) * 1995-04-18 1997-09-19 Tebro RECHARGEABLE SELF-INJECTOR
US5578011A (en) * 1995-05-11 1996-11-26 Shaw; Thomas J. Tamperproof retractable syringe
US5632733A (en) * 1995-05-11 1997-05-27 Shaw; Thomas J. Tamperproof retractable syringe
US5674204A (en) * 1995-09-19 1997-10-07 Becton Dickinson And Company Medication delivery pen cap actuated dose delivery clutch
US5688251A (en) * 1995-09-19 1997-11-18 Becton Dickinson And Company Cartridge loading and priming mechanism for a pen injector
PT928182E (en) * 1996-01-11 2002-10-31 Duoject Inc DISTRIBUTION SYSTEM FOR PHARMACEUTICAL PRODUCTS PACKED IN PHARMACEUTICAL BOTTLES
FR2749169B1 (en) 1996-06-04 1998-08-21 Delab PROCESS FOR CONSTITUTING AN INJECTABLE PREPARATION AND DEVICE FOR CARRYING OUT SAID METHOD
US5718690A (en) * 1996-06-10 1998-02-17 Gettig Technologies, Incorporated Hypodermic injector system and method for maintaining the sterility thereof prior to use
JPH1057483A (en) 1996-08-23 1998-03-03 Material Eng Tech Lab Inc Syringe and manufacture thereof
US5817058A (en) * 1996-12-23 1998-10-06 Shaw; Thomas J. Retractable catheter introducer structure
US5779679A (en) * 1997-04-18 1998-07-14 Shaw; Thomas J. Winged IV set with retractable needle
US5810775A (en) * 1997-05-23 1998-09-22 Shaw; Thomas J. Cap operated retractable medical device
USD423577S (en) * 1997-07-03 2000-04-25 Sanford, L.P. Writing implement having a grooved grip
US5957896A (en) * 1997-08-11 1999-09-28 Becton, Dickinson And Company Medication delivery pen
US5873462A (en) * 1997-09-12 1999-02-23 Becton Dickinson And Company Pen needle dispenser
US5931817A (en) * 1997-09-12 1999-08-03 Becton Dickinson And Company Pen needle assembly
US5941857A (en) * 1997-09-12 1999-08-24 Becton Dickinson And Company Disposable pen needle
US5944700A (en) * 1997-09-26 1999-08-31 Becton, Dickinson And Company Adjustable injection length pen needle
US6015438A (en) * 1997-11-14 2000-01-18 Retractable Technologies Inc. Full displacement retractable syringe
JP2002508225A (en) 1997-12-16 2002-03-19 メリディアン メディカル テクノロジーズ，インコーポレイテッド Automatic syringe
US6096010A (en) * 1998-02-20 2000-08-01 Becton, Dickinson And Company Repeat-dose medication delivery pen
US6001082A (en) * 1998-02-20 1999-12-14 Becton Dickinson And Company Medication delivery pen with an integral magnifying pocket clip
US6221053B1 (en) 1998-02-20 2001-04-24 Becton, Dickinson And Company Multi-featured medication delivery pen
US6248095B1 (en) 1998-02-23 2001-06-19 Becton, Dickinson And Company Low-cost medication delivery pen
US5997512A (en) * 1998-03-04 1999-12-07 Shaw; Thomas J. Retractable dental syringe
US6221055B1 (en) 1998-03-04 2001-04-24 Retractable Technologies, Inc. Retractable dental syringe
US6200627B1 (en) 1998-03-17 2001-03-13 Becton, Dickinson And Company Low silicone glass prefillable syringe
US6243938B1 (en) 1998-03-17 2001-06-12 Becton, Dickinson And Company Low silicone plastic prefillable syringe
US5989220A (en) * 1998-05-26 1999-11-23 Retractable Technologies Inc. Self-retracting IV catheter introducer
USD414807S (en) * 1998-05-29 1999-10-05 Sanford Corporation Writing instrument grip
WO2000004953A2 (en) 1998-07-20 2000-02-03 Cook Urological Inc. Brachytherapy device including an anti-static handle
US6346094B2 (en) 1998-09-28 2002-02-12 Becton, Dickinson And Company Pen needle magazine
USD414201S (en) * 1998-09-29 1999-09-21 Sanford Corporation Double-ended marking pen
US6086563A (en) * 1999-01-13 2000-07-11 Becton, Dickinson And Company Needle retraction mechanism with push start retraction
USD425120S (en) * 1999-01-20 2000-05-16 Sanford roting Holding GmbH Writing instrument
US6095814A (en) * 1999-01-29 2000-08-01 3M Innovative Properties Company Dispensing cartridge with stepped chamber
US6210371B1 (en) 1999-03-30 2001-04-03 Retractable Technologies, Inc. Winged I.V. set
DE60023677T2 (en) 1999-04-16 2006-08-24 Becton Dickinson And Co. PENCIL INJECTOR WITH CHARACTERISTICS FOR AUTOMATIC SUBSTANCE COMBINATION
US6277099B1 (en) 1999-08-06 2001-08-21 Becton, Dickinson And Company Medication delivery pen
US6328715B1 (en) 1999-09-21 2001-12-11 William B. Dragan Unit dose low viscosity material dispensing system
US20020193740A1 (en) 1999-10-14 2002-12-19 Alchas Paul G. Method of intradermally injecting substances
US6241710B1 (en) 1999-12-20 2001-06-05 Tricardia Llc Hypodermic needle with weeping tip and method of use
DE10006474A1 (en) * 2000-02-14 2001-08-16 Transcoject Gmbh Filling syringe for medical and other purposes, comprises removal of gas (mixture) from the syringe cylinder through hole in the piston face and subsequent plugging of this hole
USD446242S1 (en) 2000-02-22 2001-08-07 Sanford Gmbh Writing instrument
US6213597B1 (en) 2000-02-29 2001-04-10 Win-Yin Liu Apparatus for ink cartridge of a jet printer
US6572584B1 (en) 2000-08-07 2003-06-03 Retractable Technologies, Inc. Retractable syringe with reduced retraction force
USD452271S1 (en) 2000-08-24 2001-12-18 Sanford Writing instrument
USD441398S1 (en) 2000-08-24 2001-05-01 Sanford Writing instrument
US6387078B1 (en) 2000-12-21 2002-05-14 Gillespie, Iii Richard D. Automatic mixing and injecting apparatus
MXPA03007940A (en) 2001-03-13 2004-10-15 Mdc Invest Holdings Inc Pre-filled safety vial injector.
US20020164265A1 (en) 2001-05-04 2002-11-07 Hetzler Kevin G. Method of removing refractive defects in cyclic olefin medical devices
US7186241B2 (en) 2001-10-03 2007-03-06 Medical Instill Technologies, Inc. Syringe with needle penetrable and laser resealable stopper
US6494863B1 (en) 2001-10-15 2002-12-17 Retractable Technologies, Inc. One-use retracting syringe with positive needle retention
US6796967B2 (en) 2001-10-22 2004-09-28 Nps Pharmaceuticals, Inc. Injection needle assembly
US6872193B2 (en) 2001-10-26 2005-03-29 Retractable Technologies, Inc. IV catheter introducer with retractable needle
US6802828B2 (en) 2001-11-23 2004-10-12 Duoject Medical Systems, Inc. System for filling and assembling pharmaceutical delivery devices
US6743194B2 (en) 2002-03-28 2004-06-01 Igal Sharon Multi-compartment syringe
AU2003257994A1 (en) 2002-07-31 2004-02-16 Alza Corporation Injection device providing automatic needle retraction

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6183445B1 (en) * 1995-03-17 2001-02-06 Radiometer Medical A/S Syringe with retractable needle guard
US20040111064A1 (en) * 2002-12-10 2004-06-10 Asbaghi Hooman A. Position guide for a needle guard
US20050049551A1 (en) * 2003-09-03 2005-03-03 Fritz Kirchhofer Administering device with multiple-chamber ampoule and mixing block
US20060178631A1 (en) * 2004-12-09 2006-08-10 Pharma-Pen Holdings, Inc. Automatic injection and retraction syringe

Also Published As

Publication number Publication date
US7988675B2 (en) 2011-08-02
US20070135767A1 (en) 2007-06-14
WO2008094984A2 (en) 2008-08-07

Similar Documents

Publication Publication Date Title
WO2008094984A3 (en) Automatic injection and retraction devices for use with pre-filled syringe cartridges
JP5000489B2 (en) Injection device
WO2010084306A3 (en) Injection device
WO2006007556A3 (en) Passively shielding needle device
WO2014096957A3 (en) Fluid delivery device and method
WO2015014363A3 (en) Device for injecting a hypodermic syringe into a patient
ZA200909165B (en) Prefilled retractable syringe,plunger and needle assembly therefor
MX2011011541A (en) Automatic injection device.
WO2011117867A3 (en) Devices for injecting a substance and methods therefor
UA110026C2 (en) DEVICE FOR AUTOMATIC IMMEDIATE INJECTION WITH DELAY MECHANISM, INCLUDING DUAL DESTINATION
MY160282A (en) Protective device for an injection needle
CO6241134A2 (en) AN INJECTION DEVICE FOR ACCOMMODATION AND ACTIVATION OF A HYPODERMAL CRAPULA OR SYRINGE
NZ582512A (en) Syringe infusion pump for accomodating syringes with different barrel diameters with force sensor aligned with barrel axis
WO2006105006A3 (en) Safety syringe
WO2007024274A8 (en) Syringe guard for pre-filled medicament vial
WO2007028190A8 (en) Single use safety syringe having a retractable needle
WO2017033193A3 (en) Reusable automatic injection device
WO2015112536A8 (en) Force actuated injection device
MX2015017064A (en) Sliding sleeve attachment for an injection device.
WO2009013011A3 (en) Injection device for injection into biological tissue, and injection depot
GB201021735D0 (en) Autoinjectors
WO2011039230A3 (en) Drug delivery system, drug delivery device, needle assembly and method for priming
AP2011005539A0 (en) Hypodermic syringe with retractable needle.
PL1977777T3 (en) An improved barrel type plunger for use with a needle-retractable safety syringe and the syringe using the same
HRP20040679A2 (en) Improvements in and relating to a medicament delivery device

Legal Events

Date Code Title Description
NENP Non-entry into the national phase

Ref country code: DE

122 Ep: pct application non-entry in european phase

Ref document number: 08728541

Country of ref document: EP

Kind code of ref document: A2