WO2008129465A3 - Stable pharmaceutical compositions of bupropion - Google Patents
Stable pharmaceutical compositions of bupropion Download PDFInfo
- Publication number
- WO2008129465A3 WO2008129465A3 PCT/IB2008/051453 IB2008051453W WO2008129465A3 WO 2008129465 A3 WO2008129465 A3 WO 2008129465A3 IB 2008051453 W IB2008051453 W IB 2008051453W WO 2008129465 A3 WO2008129465 A3 WO 2008129465A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- bupropion
- pharmaceutical compositions
- stable pharmaceutical
- relates
- stabilizing agent
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2009—Inorganic compounds
Abstract
The present invention relates to stable pharmaceutical compositions comprising bupropion or salts thereof and a basic stabilizing agent, wherein the stabilizing agent is capable of maintaining a pH of less than 6 around bupropion particles. The invention also relates to processes for the preparation of such compositions.
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IN771/MUM/2007 | 2007-04-20 | ||
IN769MU2007 | 2007-04-20 | ||
IN771MU2007 | 2007-04-20 | ||
IN769/MUM/2007 | 2007-04-20 |
Publications (3)
Publication Number | Publication Date |
---|---|
WO2008129465A2 WO2008129465A2 (en) | 2008-10-30 |
WO2008129465A3 true WO2008129465A3 (en) | 2009-08-20 |
WO2008129465A9 WO2008129465A9 (en) | 2009-10-15 |
Family
ID=39876034
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/IB2008/051453 WO2008129465A2 (en) | 2007-04-20 | 2008-04-16 | Stable pharmaceutical compositions of bupropion |
Country Status (1)
Country | Link |
---|---|
WO (1) | WO2008129465A2 (en) |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5358970A (en) * | 1993-08-12 | 1994-10-25 | Burroughs Wellcome Co. | Pharmaceutical composition containing bupropion hydrochloride and a stabilizer |
US6238697B1 (en) * | 1998-12-21 | 2001-05-29 | Pharmalogix, Inc. | Methods and formulations for making bupropion hydrochloride tablets using direct compression |
US6333332B1 (en) * | 2000-08-25 | 2001-12-25 | Impax Laboratories, Inc. | Stabilized pharmaceutical compositions containing bupropion hydrochloride |
US20050112198A1 (en) * | 2003-10-27 | 2005-05-26 | Challapalli Prasad V. | Bupropion formulation for sustained delivery |
-
2008
- 2008-04-16 WO PCT/IB2008/051453 patent/WO2008129465A2/en active Application Filing
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5358970A (en) * | 1993-08-12 | 1994-10-25 | Burroughs Wellcome Co. | Pharmaceutical composition containing bupropion hydrochloride and a stabilizer |
US6238697B1 (en) * | 1998-12-21 | 2001-05-29 | Pharmalogix, Inc. | Methods and formulations for making bupropion hydrochloride tablets using direct compression |
US6333332B1 (en) * | 2000-08-25 | 2001-12-25 | Impax Laboratories, Inc. | Stabilized pharmaceutical compositions containing bupropion hydrochloride |
US20050112198A1 (en) * | 2003-10-27 | 2005-05-26 | Challapalli Prasad V. | Bupropion formulation for sustained delivery |
Also Published As
Publication number | Publication date |
---|---|
WO2008129465A2 (en) | 2008-10-30 |
WO2008129465A9 (en) | 2009-10-15 |
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